This web portal hosts the Immunoprecipitation-Mass Spectrometry (IP-MS) datasets used in our discovery of Endoplasmic-Reticulum-associated protein Degradation (ERAD) substrate proteins. You may browser individual datasets or search proteins by gene name or UniProt accession.

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# Cell line and sample number Explanation Species and Taxon ID
1 293_1 Anti-Sel1L IP-MS in HEK293 cells, replicate 1 Homo sapiens [9606]
2 293_2 Anti-Sel1L IP-MS in HEK293 cells, replicate 2 Homo sapiens [9606]
3 293_3 Anti-Sel1L IP-MS in HEK293 cells, replicate 3 Homo sapiens [9606]
4 BAT_2 Anti-Sel1L IP-MS in brown adipose tissue (4 degree), replicate 2 Mus musculus [10090]
5 BAT_RT2 Anti-Sel1L IP-MS in brown adipose tissue (22 degree), replicate 2 Mus musculus [10090]
6 adipocyte Anti-Sel1L IP-MS in adipocytes Mus musculus [10090]
Citation:
Wei X, Lu Y, Lin LL, Zhang C, Chen X, Wang S, Wu SA, Li ZJ, Quan Y, Sun S, Qi L (2024) Proteomic screens of SEL1L-HRD1 ER-associated degradation substrates reveal its role in glycosylphosphatidylinositol-anchored protein biogenesis. Nature Communications, 15(1), p.659.

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