| Protein FDR Confidence: Combined | Accession | Description | Exp. q-value: Combined | Sum PEP Score | Coverage [%] | # Peptides | # PSMs | # Unique Peptides | # AAs | MW [kDa] | calc. pI | # Peptides (by Search Engine): A2 Sequest HT (IgG 293) | # Peptides (by Search Engine): B2 Sequest HT (Sel1L 293) | # Peptides (by Search Engine): C2 Sequest HT (WT 293) | # Peptides (by Search Engine): D2 Sequest HT (HKO 293) | # PSMs (by Search Engine): A2 Sequest HT (IgG 293) | # PSMs (by Search Engine): B2 Sequest HT (Sel1L 293) | # PSMs (by Search Engine): C2 Sequest HT (WT 293) | # PSMs (by Search Engine): D2 Sequest HT (HKO 293) | Abundance: F1: Sample, IgG 293 | Abundance: F2: Sample, Sel1L 293 | Abundance: F3: Sample, WT 293 | Abundance: F4: Sample, HKO 293 | Abundances Count: F1: Sample, IgG 293 | Abundances Count: F2: Sample, Sel1L 293 | Abundances Count: F3: Sample, WT 293 | Abundances Count: F4: Sample, HKO 293 | Modifications | Biological Process | Cellular Component | Molecular Function | Pfam IDs | Entrez Gene ID | Ensembl Gene ID | Gene Symbol | Chromosome | Reactome Pathways | KEGG Pathways | # Razor Peptides |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| High | P02545 | Prelamin-A/C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 | 0 | 34.13 | 26 | 14 | 20 | 14 | 664 | 74.1 | 7.02 | 13 | 4 | 1 | 15 | 4 | 1 | 986716.4063 | 16943288.19 | 3411021.922 | 2226611.109 | 4 | 11 | 7 | 7 | cell organization and biogenesis;regulation of biological process;response to stimulus;transport | cytosol;membrane;nucleus | protein binding;structural molecule activity | "Pf00038, Pf00932" | 4000 | ENSG00000160789.19 | LMNA | 1 | Signaling by BRAF and RAF fusions; Breakdown of the nuclear lamina; XBP1(S) activates chaperone genes; Initiation of Nuclear Envelope Reformation; Clearance of Nuclear Envelope Membranes from Chromatin; Depolymerisation of the Nuclear Lamina; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | Arrhythmogenic right ventricular cardiomyopathy (ARVC); Dilated cardiomyopathy; Apoptosis; Hypertrophic cardiomyopathy (HCM) | 0 |