Protein FDR Confidence: CombinedAccessionDescriptionExp. q-value: CombinedSum PEP ScoreCoverage [%]# Peptides# PSMs# Unique Peptides# AAsMW [kDa]calc. pI# Peptides (by Search Engine): A2 Sequest HT (IgG 293)# Peptides (by Search Engine): B2 Sequest HT (Sel1L 293)# Peptides (by Search Engine): C2 Sequest HT (WT 293)# Peptides (by Search Engine): D2 Sequest HT (HKO 293)# PSMs (by Search Engine): A2 Sequest HT (IgG 293)# PSMs (by Search Engine): B2 Sequest HT (Sel1L 293)# PSMs (by Search Engine): C2 Sequest HT (WT 293)# PSMs (by Search Engine): D2 Sequest HT (HKO 293)Abundance: F1: Sample, IgG 293Abundance: F2: Sample, Sel1L 293Abundance: F3: Sample, WT 293Abundance: F4: Sample, HKO 293Abundances Count: F1: Sample, IgG 293Abundances Count: F2: Sample, Sel1L 293Abundances Count: F3: Sample, WT 293Abundances Count: F4: Sample, HKO 293ModificationsBiological ProcessCellular ComponentMolecular FunctionPfam IDsEntrez Gene IDEnsembl Gene IDGene SymbolChromosomeReactome PathwaysKEGG Pathways# Razor Peptides
HighP06493Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=305.1381136229734.18.41221232380524.1722490099.9062542616.3131907369.6252222cell death;cell differentiation;cell division;cell organization and biogenesis;cell proliferation;cellular component movement;metabolic process;regulation of biological process;response to stimuluscytoplasm;cytoskeleton;cytosol;membrane;mitochondrion;nucleus;organelle lumencatalytic activity;nucleotide binding;protein binding;receptor activity"Pf00069, Pf01636, Pf07714, Pf14531"983ENSG00000170312.15CDK110"Regulation of PLK1 Activity at G2/M Transition; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Recruitment of NuMA to mitotic centrosomes; Ovarian tumor domain proteases; Loss of Nlp from mitotic centrosomes; Activation of E2F1 target genes at G1/S; MASTL Facilitates Mitotic Progression; Golgi Cisternae Pericentriolar Stack Reorganization; Activation of NIMA Kinases NEK9, NEK6, NEK7; The role of GTSE1 in G2/M progression after G2 checkpoint; Nuclear Pore Complex (NPC) Disassembly; Transcriptional regulation by RUNX2; Interleukin-20 family signaling; APC/C:Cdc20 mediated degradation of Cyclin B; G2/M DNA replication checkpoint; Condensation of Prometaphase Chromosomes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; AURKA Activation by TPX2; Anchoring of the basal body to the plasma membrane; Regulation of TP53 Degradation; Phosphorylation of Emi1; MAPK3 (ERK1) activation; Recruitment of mitotic centrosome proteins and complexes; Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes; E2F-enabled inhibition of pre-replication complex formation; Phosphorylation of the APC/C; Depolymerisation of the Nuclear Lamina; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; Resolution of Sister Chromatid Cohesion; Condensation of Prophase Chromosomes; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling"Viral carcinogenesis; Epstein-Barr virus infection; Progesterone-mediated oocyte maturation; Gap junction; p53 signaling pathway; Oocyte meiosis; Herpes simplex infection; Cell cycle0

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