High | P12270 | Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 | 0 | 5.815 | 2 | 3 | 4 | 3 | 2363 | 267.1 | 5.02 | 3 | | 1 | | 3 | | 1 | | 413469.625 | | 172764.375 | 156802.8438 | 2 | | 1 | 1 | Met-loss+Acetyl [N-Term] | cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport | chromosome;cytoplasm;cytoskeleton;membrane;nucleus | catalytic activity;motor activity;protein binding;RNA binding;structural molecule activity;transporter activity | "Pf00038, Pf01496, Pf01576, Pf02463, Pf03961, Pf04111, Pf05911, Pf07888, Pf07926, Pf09726, Pf12128, Pf13166, Pf13514" | 7175 | ENSG00000047410.13 | TPR | 1 | Rev-mediated nuclear export of HIV RNA; ISG15 antiviral mechanism; NEP/NS2 Interacts with the Cellular Export Machinery; tRNA processing in the nucleus; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); Nuclear Pore Complex (NPC) Disassembly; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; Regulation of HSF1-mediated heat shock response; snRNP Assembly; SUMOylation of DNA replication proteins; Transport of the SLBP independent Mature mRNA; SUMOylation of RNA binding proteins; Viral Messenger RNA Synthesis; SUMOylation of chromatin organization proteins; Nuclear import of Rev protein; NS1 Mediated Effects on Host Pathways; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of the SLBP Dependant Mature mRNA; Transport of Ribonucleoproteins into the Host Nucleus; Transport of Mature mRNA derived from an Intron-Containing Transcript; SUMOylation of DNA damage response and repair proteins | Pathways in cancer; RNA transport; Thyroid cancer | 0 |