Protein FDR Confidence: CombinedAccessionDescriptionExp. q-value: CombinedSum PEP ScoreCoverage [%]# Peptides# PSMs# Unique Peptides# AAsMW [kDa]calc. pI# Peptides (by Search Engine): A2 Sequest HT (IgG 293)# Peptides (by Search Engine): B2 Sequest HT (Sel1L 293)# Peptides (by Search Engine): C2 Sequest HT (WT 293)# Peptides (by Search Engine): D2 Sequest HT (HKO 293)# PSMs (by Search Engine): A2 Sequest HT (IgG 293)# PSMs (by Search Engine): B2 Sequest HT (Sel1L 293)# PSMs (by Search Engine): C2 Sequest HT (WT 293)# PSMs (by Search Engine): D2 Sequest HT (HKO 293)Abundance: F1: Sample, IgG 293Abundance: F2: Sample, Sel1L 293Abundance: F3: Sample, WT 293Abundance: F4: Sample, HKO 293Abundances Count: F1: Sample, IgG 293Abundances Count: F2: Sample, Sel1L 293Abundances Count: F3: Sample, WT 293Abundances Count: F4: Sample, HKO 293ModificationsBiological ProcessCellular ComponentMolecular FunctionPfam IDsEntrez Gene IDEnsembl Gene IDGene SymbolChromosomeReactome PathwaysKEGG Pathways# Razor Peptides
HighP30153Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4012.3291045458965.35.11212212759321.65631703574.9381993338.52257856.52222Met-loss+Acetyl [N-Term]cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimuluschromosome;cytoplasm;cytoskeleton;cytosol;membrane;mitochondrion;nucleuscatalytic activity;enzyme regulator activity;protein binding"Pf02985, Pf13513, Pf13646"5518ENSG00000105568.17PPP2R1A19"Glycolysis; Regulation of PLK1 Activity at G2/M Transition; AXIN missense mutants destabilize the destruction complex; PP2A-mediated dephosphorylation of key metabolic factors; APC truncation mutants have impaired AXIN binding; CTLA4 inhibitory signaling; Activated TLR4 signalling; Separation of Sister Chromatids; MASTL Facilitates Mitotic Progression; S37 mutants of beta-catenin aren't phosphorylated; AURKA Activation by TPX2; S33 mutants of beta-catenin aren't phosphorylated; Anchoring of the basal body to the plasma membrane; S45 mutants of beta-catenin aren't phosphorylated; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Recruitment of mitotic centrosome proteins and complexes; Misspliced GSK3beta mutants stabilize beta-catenin; Cyclin A/B1/B2 associated events during G2/M transition; T41 mutants of beta-catenin aren't phosphorylated; RAF activation; ERKs are inactivated; Beta-catenin phosphorylation cascade; Negative regulation of MAPK pathway; Recruitment of NuMA to mitotic centrosomes; Initiation of Nuclear Envelope Reformation; Loss of Nlp from mitotic centrosomes; Platelet sensitization by LDL; Signaling by GPCR; Interleukin-20 family signaling; Spry regulation of FGF signaling; DARPP-32 events; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Regulation of TP53 Degradation; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Cyclin D associated events in G1; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; Truncations of AMER1 destabilize the destruction complex"Dopaminergic synapse; Chagas disease (American trypanosomiasis); TGF-beta signaling pathway; Tight junction; Hippo signaling pathway; Adrenergic signaling in cardiomyocytes; AMPK signaling pathway; Long-term depression; mRNA surveillance pathway; Oocyte meiosis; Sphingolipid signaling pathway; Hepatitis C; PI3K-Akt signaling pathway0

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