Protein FDR Confidence: CombinedAccessionDescriptionExp. q-value: CombinedSum PEP ScoreCoverage [%]# Peptides# PSMs# Unique Peptides# AAsMW [kDa]calc. pI# Peptides (by Search Engine): A2 Sequest HT (IgG 293)# Peptides (by Search Engine): B2 Sequest HT (Sel1L 293)# Peptides (by Search Engine): C2 Sequest HT (WT 293)# Peptides (by Search Engine): D2 Sequest HT (HKO 293)# PSMs (by Search Engine): A2 Sequest HT (IgG 293)# PSMs (by Search Engine): B2 Sequest HT (Sel1L 293)# PSMs (by Search Engine): C2 Sequest HT (WT 293)# PSMs (by Search Engine): D2 Sequest HT (HKO 293)Abundance: F1: Sample, IgG 293Abundance: F2: Sample, Sel1L 293Abundance: F3: Sample, WT 293Abundance: F4: Sample, HKO 293Abundances Count: F1: Sample, IgG 293Abundances Count: F2: Sample, Sel1L 293Abundances Count: F3: Sample, WT 293Abundances Count: F4: Sample, HKO 293ModificationsBiological ProcessCellular ComponentMolecular FunctionPfam IDsEntrez Gene IDEnsembl Gene IDGene SymbolChromosomeReactome PathwaysKEGG Pathways# Razor Peptides
HighP49841Glycogen synthase kinase-3 beta OS=Homo sapiens OX=9606 GN=GSK3B PE=1 SV=202.84722142046.78.781111179436.625768205.5625440697.2813111cell differentiation;cell organization and biogenesis;development;metabolic process;regulation of biological process;response to stimuluscytoplasm;cytosol;membrane;mitochondrion;nucleuscatalytic activity;nucleotide binding;protein binding"Pf00069, Pf01636, Pf07714, Pf14531"2932ENSG00000082701.14GSK3B3Regulation of RUNX2 expression and activity; AKT phosphorylates targets in the cytosol; S37 mutants of beta-catenin aren't phosphorylated; Beta-catenin phosphorylation cascade; AXIN missense mutants destabilize the destruction complex; S33 mutants of beta-catenin aren't phosphorylated; CRMPs in Sema3A signaling; Regulation of HSF1-mediated heat shock response; Disassembly of the destruction complex and recruitment of AXIN to the membrane; APC truncation mutants have impaired AXIN binding; S45 mutants of beta-catenin aren't phosphorylated; GLI3 is processed to GLI3R by the proteasome; Misspliced GSK3beta mutants stabilize beta-catenin; Constitutive Signaling by AKT1 E17K in Cancer; Degradation of GLI2 by the proteasome; T41 mutants of beta-catenin aren't phosphorylated; B-WICH complex positively regulates rRNA expression; Truncations of AMER1 destabilize the destruction complexDopaminergic synapse; T cell receptor signaling pathway; Insulin signaling pathway; Prolactin signaling pathway; Epstein-Barr virus infection; Neurotrophin signaling pathway; B cell receptor signaling pathway; Hippo signaling pathway; Endometrial cancer; Breast cancer; Colorectal cancer; ErbB signaling pathway; Pathways in cancer; Prostate cancer; Thyroid hormone signaling pathway; EGFR tyrosine kinase inhibitor resistance; HTLV-I infection; Melanogenesis; Wnt signaling pathway; Focal adhesion; Alzheimer's disease; mTOR signaling pathway; Non-alcoholic fatty liver disease (NAFLD); Hedgehog signaling pathway; Measles; Hepatitis C; Cell cycle; Chemokine signaling pathway; Axon guidance; Basal cell carcinoma; Signaling pathways regulating pluripotency of stem cells; Influenza A; Insulin resistance; PI3K-Akt signaling pathway0

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