Protein FDR Confidence: Combined	Accession	Description	Exp. q-value: Combined	Sum PEP Score	Coverage [%]	# Peptides	# PSMs	# Unique Peptides	# AAs	MW [kDa]	calc. pI	# Peptides (by Search Engine): A2 Sequest HT (IgG 293)	# Peptides (by Search Engine): B2 Sequest HT (Sel1L 293)	# Peptides (by Search Engine): C2 Sequest HT (WT 293)	# Peptides (by Search Engine): D2 Sequest HT (HKO 293)	# PSMs (by Search Engine): A2 Sequest HT (IgG 293)	# PSMs (by Search Engine): B2 Sequest HT (Sel1L 293)	# PSMs (by Search Engine): C2 Sequest HT (WT 293)	# PSMs (by Search Engine): D2 Sequest HT (HKO 293)	Abundance: F1: Sample, IgG 293	Abundance: F2: Sample, Sel1L 293	Abundance: F3: Sample, WT 293	Abundance: F4: Sample, HKO 293	Abundances Count: F1: Sample, IgG 293	Abundances Count: F2: Sample, Sel1L 293	Abundances Count: F3: Sample, WT 293	Abundances Count: F4: Sample, HKO 293	Modifications	Biological Process	Cellular Component	Molecular Function	Pfam IDs	Entrez Gene ID	Ensembl Gene ID	Gene Symbol	Chromosome	Reactome Pathways	KEGG Pathways	# Razor Peptides
High	P49959	Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3	0	7.521	9	4	4	4	708	80.5	5.9		4				4			299263.3438	2766019.563	664727.125	476506.8281	1	3	2	2		cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process;response to stimulus	chromosome;cytoplasm;cytosol;nucleus	catalytic activity;DNA binding;metal ion binding;protein binding	"Pf00149, Pf04152"	4361	ENSG00000020922.12	MRE11A; MRE11	11	G2/M DNA damage checkpoint; IRF3-mediated induction of type I IFN; Presynaptic phase of homologous DNA pairing and strand exchange; Nonhomologous End-Joining (NHEJ); Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Meiotic recombination; Sensing of DNA Double Strand Breaks; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; HDR through Single Strand Annealing (SSA); HDR through MMEJ (alt-NHEJ); DNA Damage/Telomere Stress Induced Senescence; Regulation of TP53 Activity through Phosphorylation; Resolution of D-loop Structures through Holliday Junction Intermediates	Homologous recombination; Non-homologous end-joining	0

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