Protein FDR Confidence: Combined	Accession	Description	Exp. q-value: Combined	Sum PEP Score	Coverage [%]	# Peptides	# PSMs	# Unique Peptides	# AAs	MW [kDa]	calc. pI	# Peptides (by Search Engine): A2 Sequest HT (IgG 293)	# Peptides (by Search Engine): B2 Sequest HT (Sel1L 293)	# Peptides (by Search Engine): C2 Sequest HT (WT 293)	# Peptides (by Search Engine): D2 Sequest HT (HKO 293)	# PSMs (by Search Engine): A2 Sequest HT (IgG 293)	# PSMs (by Search Engine): B2 Sequest HT (Sel1L 293)	# PSMs (by Search Engine): C2 Sequest HT (WT 293)	# PSMs (by Search Engine): D2 Sequest HT (HKO 293)	Abundance: F1: Sample, IgG 293	Abundance: F2: Sample, Sel1L 293	Abundance: F3: Sample, WT 293	Abundance: F4: Sample, HKO 293	Abundances Count: F1: Sample, IgG 293	Abundances Count: F2: Sample, Sel1L 293	Abundances Count: F3: Sample, WT 293	Abundances Count: F4: Sample, HKO 293	Modifications	Biological Process	Cellular Component	Molecular Function	Pfam IDs	Entrez Gene ID	Ensembl Gene ID	Gene Symbol	Chromosome	Reactome Pathways	KEGG Pathways	# Razor Peptides
High	P62993	Growth factor receptor-bound protein 2 OS=Homo sapiens OX=9606 GN=GRB2 PE=1 SV=1	0	15.671	33	5	14	5	217	25.2	6.32	1	4	4	4	1	4	4	5	754557.3125	4107131.438	5978074	4713633.844	2	4	4	5		cell communication;cell differentiation;cell organization and biogenesis;cellular component movement;defense response;metabolic process;regulation of biological process;response to stimulus;transport	cytoplasm;cytosol;endosome;Golgi;membrane;nucleus	catalytic activity;protein binding;RNA binding	"Pf00017, Pf00018, Pf07653, Pf14604"	2885	ENSG00000177885.13	GRB2	17	"PI3K Cascade; SHC-mediated cascade:FGFR4; Signaling by FGFR4 in disease; PI-3K cascade:FGFR3; FRS-mediated FGFR4 signaling; Signal regulatory protein family interactions; EGFR downregulation; SHC1 events in ERBB4 signaling; NCAM signaling for neurite out-growth; DAP12 signaling; PI-3K cascade:FGFR4; GRB2 events in EGFR signaling; Regulation of signaling by CBL; Regulation of actin dynamics for phagocytic cup formation; Signaling by cytosolic FGFR1 fusion mutants; MET activates PI3K/AKT signaling; Constitutive Signaling by EGFRvIII; GRB2:SOS provides linkage to MAPK signaling for Integrins ; Interleukin receptor SHC signaling; MET receptor recycling; FRS-mediated FGFR3 signaling; SHC-mediated cascade:FGFR3; Negative regulation of MET activity; FRS-mediated FGFR2 signaling; CD28 dependent Vav1 pathway; Signalling to RAS; GPVI-mediated activation cascade; FRS-mediated FGFR1 signaling; PI-3K cascade:FGFR2; RET signaling; SHC-mediated cascade:FGFR1; GRB2 events in ERBB2 signaling; PI-3K cascade:FGFR1; PI3K events in ERBB2 signaling; Role of LAT2/NTAL/LAB on calcium mobilization; RAF/MAP kinase cascade; Tie2 Signaling; FCERI mediated Ca+2 mobilization; SHC1 events in ERBB2 signaling; SHC-related events triggered by IGF1R; Signaling by FGFR2 in disease; FCERI mediated MAPK activation; Signaling by FGFR3 fusions in cancer; G beta:gamma signalling through PI3Kgamma; MET activates RAP1 and RAC1; Downstream signal transduction; Signaling by FGFR3 point mutants in cancer; MET activates RAS signaling; MET activates PTPN11; Signal attenuation; SHC-mediated cascade:FGFR2; EGFR Transactivation by Gastrin; Constitutive Signaling by Aberrant PI3K in Cancer; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; SOS-mediated signalling; Interleukin-20 family signaling; Interleukin-15 signaling; Spry regulation of FGF signaling; Cargo recognition for clathrin-mediated endocytosis; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; SHC1 events in EGFR signaling; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; RHO GTPases Activate WASPs and WAVEs; Regulation of KIT signaling; GAB1 signalosome; InlB-mediated entry of Listeria monocytogenes into host cell"	Viral carcinogenesis; T cell receptor signaling pathway; Dorso-ventral axis formation; Osteoclast differentiation; Hepatitis B; Insulin signaling pathway; FoxO signaling pathway; Prolactin signaling pathway; MicroRNAs in cancer; Phospholipase D signaling pathway; Chronic myeloid leukemia; Neurotrophin signaling pathway; B cell receptor signaling pathway; Acute myeloid leukemia; Non-small cell lung cancer; MAPK signaling pathway; Endometrial cancer; Breast cancer; Natural killer cell mediated cytotoxicity; ErbB signaling pathway; Pathways in cancer; Prostate cancer; Glioma; Gap junction; Renal cell carcinoma; EGFR tyrosine kinase inhibitor resistance; Focal adhesion; Jak-STAT signaling pathway; Proteoglycans in cancer; Choline metabolism in cancer; mTOR signaling pathway; Fc epsilon RI signaling pathway; Hepatitis C; Alcoholism; Ras signaling pathway; Endocrine resistance; GnRH signaling pathway; Chemokine signaling pathway; Signaling pathways regulating pluripotency of stem cells; Estrogen signaling pathway; PI3K-Akt signaling pathway	0

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