Protein FDR Confidence: Combined	Accession	Description	Exp. q-value: Combined	Sum PEP Score	Coverage [%]	# Peptides	# PSMs	# Unique Peptides	# AAs	MW [kDa]	calc. pI	# Peptides (by Search Engine): A2 Sequest HT (IgG 293)	# Peptides (by Search Engine): B2 Sequest HT (Sel1L 293)	# Peptides (by Search Engine): C2 Sequest HT (WT 293)	# Peptides (by Search Engine): D2 Sequest HT (HKO 293)	# PSMs (by Search Engine): A2 Sequest HT (IgG 293)	# PSMs (by Search Engine): B2 Sequest HT (Sel1L 293)	# PSMs (by Search Engine): C2 Sequest HT (WT 293)	# PSMs (by Search Engine): D2 Sequest HT (HKO 293)	Abundance: F1: Sample, IgG 293	Abundance: F2: Sample, Sel1L 293	Abundance: F3: Sample, WT 293	Abundance: F4: Sample, HKO 293	Abundances Count: F1: Sample, IgG 293	Abundances Count: F2: Sample, Sel1L 293	Abundances Count: F3: Sample, WT 293	Abundances Count: F4: Sample, HKO 293	Modifications	Biological Process	Cellular Component	Molecular Function	Pfam IDs	Entrez Gene ID	Ensembl Gene ID	Gene Symbol	Chromosome	Reactome Pathways	KEGG Pathways	# Razor Peptides
High	P63261	"Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1"	0	88.293	55	15	106	1	375	41.8	5.48	9	13	13	14	19	25	33	29	2223655.5	1697390.359	2800995.406	657568.7734	2	2	2	2	Met-loss+Acetyl [N-Term]	cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus	cytoplasm;cytoskeleton;cytosol;membrane;nucleus	nucleotide binding;protein binding;structural molecule activity	Pf00022	71	ENSG00000184009.9	ACTG1	17	Signaling by BRAF and RAF fusions; Formation of annular gap junctions; Cell-extracellular matrix interactions; MAP2K and MAPK activation; Clathrin-mediated endocytosis; Interaction between L1 and Ankyrins; VEGFA-VEGFR2 Pathway; RHO GTPases activate IQGAPs; Signaling by RAS mutants; Recycling pathway of L1; Signaling by high-kinase activity BRAF mutants; Signaling by moderate kinase activity BRAF mutants; Translocation of GLUT4 to the plasma membrane; Adherens junctions interactions; EPH-ephrin mediated repulsion of cells; Paradoxical activation of RAF signaling by kinase inactive BRAF; EPHB-mediated forward signaling; RHO GTPases Activate WASPs and WAVEs; Regulation of actin dynamics for phagocytic cup formation; RHO GTPases Activate Formins; Interleukin-20 family signaling	Arrhythmogenic right ventricular cardiomyopathy (ARVC); Tight junction; Pathogenic Escherichia coli infection; Dilated cardiomyopathy; Hippo signaling pathway; Rap1 signaling pathway; Oxytocin signaling pathway; Thyroid hormone signaling pathway; Phagosome; Apoptosis; Focal adhesion; Proteoglycans in cancer; Salmonella infection; Adherens junction; Regulation of actin cytoskeleton; Leukocyte transendothelial migration; Bacterial invasion of epithelial cells; Vibrio cholerae infection; Viral myocarditis; Influenza A; Hypertrophic cardiomyopathy (HCM); Platelet activation; Shigellosis	0

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