| Protein FDR Confidence: Combined | Accession | Description | Exp. q-value: Combined | Sum PEP Score | Coverage [%] | # Peptides | # PSMs | # Unique Peptides | # AAs | MW [kDa] | calc. pI | # Peptides (by Search Engine): A2 Sequest HT (IgG 293) | # Peptides (by Search Engine): B2 Sequest HT (Sel1L 293) | # Peptides (by Search Engine): C2 Sequest HT (WT 293) | # Peptides (by Search Engine): D2 Sequest HT (HKO 293) | # PSMs (by Search Engine): A2 Sequest HT (IgG 293) | # PSMs (by Search Engine): B2 Sequest HT (Sel1L 293) | # PSMs (by Search Engine): C2 Sequest HT (WT 293) | # PSMs (by Search Engine): D2 Sequest HT (HKO 293) | Abundance: F1: Sample, IgG 293 | Abundance: F2: Sample, Sel1L 293 | Abundance: F3: Sample, WT 293 | Abundance: F4: Sample, HKO 293 | Abundances Count: F1: Sample, IgG 293 | Abundances Count: F2: Sample, Sel1L 293 | Abundances Count: F3: Sample, WT 293 | Abundances Count: F4: Sample, HKO 293 | Modifications | Biological Process | Cellular Component | Molecular Function | Pfam IDs | Entrez Gene ID | Ensembl Gene ID | Gene Symbol | Chromosome | Reactome Pathways | KEGG Pathways | # Razor Peptides |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| High | P98170 | E3 ubiquitin-protein ligase XIAP OS=Homo sapiens OX=9606 GN=XIAP PE=1 SV=2 | 0 | 3.546 | 4 | 1 | 2 | 1 | 497 | 56.6 | 6.65 | 1 | 1 | 1 | 1 | 477340.0313 | 1168691.375 | 827319.9375 | 567394.5 | 1 | 1 | 1 | 1 | cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus | cytoplasm;cytosol;nucleus | catalytic activity;enzyme regulator activity;metal ion binding;protein binding | "Pf00653, Pf13920, Pf13923" | 331 | ENSG00000101966.12 | XIAP | X | Regulation of PTEN stability and activity; Deactivation of the beta-catenin transactivating complex; Regulation of necroptotic cell death; SMAC-mediated dissociation of IAP:caspase complexes ; SMAC binds to IAPs ; Regulation of TNFR1 signaling; TNFR1-induced NFkappaB signaling pathway; Regulation of PTEN localization | NOD-like receptor signaling pathway; Ubiquitin mediated proteolysis; Pathways in cancer; Apoptosis - multiple species; NF-kappa B signaling pathway; HTLV-I infection; Toxoplasmosis; Apoptosis; Focal adhesion; Small cell lung cancer; Platinum drug resistance | 0 |