Protein FDR Confidence: CombinedAccessionDescriptionExp. q-value: CombinedSum PEP ScoreCoverage [%]# Peptides# PSMs# Unique Peptides# AAsMW [kDa]calc. pI# Peptides (by Search Engine): A2 Sequest HT (IgG 293)# Peptides (by Search Engine): B2 Sequest HT (Sel1L 293)# Peptides (by Search Engine): C2 Sequest HT (WT 293)# Peptides (by Search Engine): D2 Sequest HT (HKO 293)# PSMs (by Search Engine): A2 Sequest HT (IgG 293)# PSMs (by Search Engine): B2 Sequest HT (Sel1L 293)# PSMs (by Search Engine): C2 Sequest HT (WT 293)# PSMs (by Search Engine): D2 Sequest HT (HKO 293)Abundance: F1: Sample, IgG 293Abundance: F2: Sample, Sel1L 293Abundance: F3: Sample, WT 293Abundance: F4: Sample, HKO 293Abundances Count: F1: Sample, IgG 293Abundances Count: F2: Sample, Sel1L 293Abundances Count: F3: Sample, WT 293Abundances Count: F4: Sample, HKO 293ModificationsBiological ProcessCellular ComponentMolecular FunctionPfam IDsEntrez Gene IDEnsembl Gene IDGene SymbolChromosomeReactome PathwaysKEGG Pathways# Razor Peptides
HighQ14191Werner syndrome ATP-dependent helicase OS=Homo sapiens OX=9606 GN=WRN PE=1 SV=2035.52291420141432162.46.3413416429422966.816894942.2191570474.46912104cell communication;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transportcytoplasm;nucleuscatalytic activity;DNA binding;metal ion binding;nucleotide binding;protein binding"Pf00270, Pf00271, Pf00570, Pf01612, Pf09382, Pf14493"7486ENSG00000165392.9WRN8G2/M DNA damage checkpoint; Presynaptic phase of homologous DNA pairing and strand exchange; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Processing of DNA double-strand break ends; HDR through Single Strand Annealing (SSA); Regulation of TP53 Activity through Phosphorylation; SUMOylation of DNA damage response and repair proteins; Resolution of D-loop Structures through Holliday Junction Intermediates0

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