Protein FDR Confidence: Combined	Accession	Description	Exp. q-value: Combined	Sum PEP Score	Coverage [%]	# Peptides	# PSMs	# Unique Peptides	# AAs	MW [kDa]	calc. pI	# Peptides (by Search Engine): A2 Sequest HT (IgG 293)	# Peptides (by Search Engine): B2 Sequest HT (Sel1L 293)	# Peptides (by Search Engine): C2 Sequest HT (WT 293)	# Peptides (by Search Engine): D2 Sequest HT (HKO 293)	# PSMs (by Search Engine): A2 Sequest HT (IgG 293)	# PSMs (by Search Engine): B2 Sequest HT (Sel1L 293)	# PSMs (by Search Engine): C2 Sequest HT (WT 293)	# PSMs (by Search Engine): D2 Sequest HT (HKO 293)	Abundance: F1: Sample, IgG 293	Abundance: F2: Sample, Sel1L 293	Abundance: F3: Sample, WT 293	Abundance: F4: Sample, HKO 293	Abundances Count: F1: Sample, IgG 293	Abundances Count: F2: Sample, Sel1L 293	Abundances Count: F3: Sample, WT 293	Abundances Count: F4: Sample, HKO 293	Modifications	Biological Process	Cellular Component	Molecular Function	Pfam IDs	Entrez Gene ID	Ensembl Gene ID	Gene Symbol	Chromosome	Reactome Pathways	KEGG Pathways	# Razor Peptides
High	Q16777	Histone H2A type 2-C OS=Homo sapiens OX=9606 GN=H2AC20 PE=1 SV=4	0	27.698	41	7	38	2	129	14	10.9	3	5	7	4	7	9	14	8	20072852.84	56194920.94	101849030.4	28630400.22	6	6	8	5		regulation of biological process	chromosome;nucleus	DNA binding;protein binding	"Pf00125, Pf00808"	8338	ENSG00000184260.5	HIST2H2AC	1	SIRT1 negatively regulates rRNA expression; UCH proteinases; RMTs methylate histone arginines; Activation of anterior HOX genes in hindbrain development during early embryogenesis; NoRC negatively regulates rRNA expression; Meiotic synapsis; Transcriptional regulation by small RNAs; Meiotic recombination; PRC2 methylates histones and DNA; HDACs deacetylate histones; Formation of the beta-catenin:TCF transactivating complex; Metalloprotease DUBs; DNA methylation; Packaging Of Telomere Ends; Ub-specific processing proteases; Amyloid fiber formation; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; RUNX1 regulates transcription of genes involved in differentiation of HSCs; RNA Polymerase I Chain Elongation; HATs acetylate histones; Deposition of new CENPA-containing nucleosomes at the centromere; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); B-WICH complex positively regulates rRNA expression; RNA Polymerase I Promoter Opening; Oxidative Stress Induced Senescence	Systemic lupus erythematosus; Alcoholism	6

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