High | Q16778 | Histone H2B type 2-E OS=Homo sapiens OX=9606 GN=H2BC21 PE=1 SV=3 | 0 | 19.796 | 47 | 6 | 37 | 1 | 126 | 13.9 | 10.32 | 4 | 4 | 6 | 3 | 8 | 8 | 14 | 7 | 23407851.31 | 56222953.69 | 143067680.5 | 29071918.5 | 5 | 5 | 7 | 4 | | cell organization and biogenesis;defense response;response to stimulus | chromosome;cytosol;nucleus | DNA binding;protein binding | "Pf00125, Pf00808" | 8349 | ENSG00000184678.10 | HIST2H2BE | 1 | SIRT1 negatively regulates rRNA expression; Nonhomologous End-Joining (NHEJ); Activation of anterior HOX genes in hindbrain development during early embryogenesis; NoRC negatively regulates rRNA expression; Meiotic synapsis; Transcriptional regulation by small RNAs; Meiotic recombination; PRC2 methylates histones and DNA; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; HDACs deacetylate histones; Formation of the beta-catenin:TCF transactivating complex; DNA methylation; G2/M DNA damage checkpoint; Packaging Of Telomere Ends; Ub-specific processing proteases; Amyloid fiber formation; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; RUNX1 regulates transcription of genes involved in differentiation of HSCs; RNA Polymerase I Chain Elongation; HATs acetylate histones; Deposition of new CENPA-containing nucleosomes at the centromere; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Condensation of Prophase Chromosomes; Processing of DNA double-strand break ends; DNA Damage/Telomere Stress Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); B-WICH complex positively regulates rRNA expression; RNA Polymerase I Promoter Opening; Oxidative Stress Induced Senescence | Viral carcinogenesis; Systemic lupus erythematosus; Alcoholism | 6 |