Protein FDR Confidence: Combined	Accession	Description	Exp. q-value: Combined	Sum PEP Score	Coverage [%]	# Peptides	# PSMs	# Unique Peptides	# AAs	MW [kDa]	calc. pI	# Peptides (by Search Engine): A2 Sequest HT (IgG 293)	# Peptides (by Search Engine): B2 Sequest HT (Sel1L 293)	# Peptides (by Search Engine): C2 Sequest HT (WT 293)	# Peptides (by Search Engine): D2 Sequest HT (HKO 293)	# PSMs (by Search Engine): A2 Sequest HT (IgG 293)	# PSMs (by Search Engine): B2 Sequest HT (Sel1L 293)	# PSMs (by Search Engine): C2 Sequest HT (WT 293)	# PSMs (by Search Engine): D2 Sequest HT (HKO 293)	Abundance: F1: Sample, IgG 293	Abundance: F2: Sample, Sel1L 293	Abundance: F3: Sample, WT 293	Abundance: F4: Sample, HKO 293	Abundances Count: F1: Sample, IgG 293	Abundances Count: F2: Sample, Sel1L 293	Abundances Count: F3: Sample, WT 293	Abundances Count: F4: Sample, HKO 293	Modifications	Biological Process	Cellular Component	Molecular Function	Pfam IDs	Entrez Gene ID	Ensembl Gene ID	Gene Symbol	Chromosome	Reactome Pathways	KEGG Pathways	# Razor Peptides
High	Q92542	Nicastrin OS=Homo sapiens OX=9606 GN=NCSTN PE=1 SV=2	0	10.524	6	4	6	4	709	78.4	5.99			1	4			1	5		106602.6016	1541325.063	2640834.688		1	2	3		cell proliferation;metabolic process;regulation of biological process;response to stimulus;transport	endoplasmic reticulum;Golgi;membrane	catalytic activity;protein binding	Pf05450	23385	ENSG00000162736.15	NCSTN	1	Activated NOTCH1 Transmits Signal to the Nucleus; Signaling by NOTCH4; Regulated proteolysis of p75NTR; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NRIF signals cell death from the nucleus; Signaling by NOTCH3; EPH-ephrin mediated repulsion of cells; NOTCH2 Activation and Transmission of Signal to the Nucleus; Degradation of the extracellular matrix; Neutrophil degranulation; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Nuclear signaling by ERBB4; Signalling by NGF	Alzheimer's disease; Notch signaling pathway	0

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