High | Q92878 | DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 | 0 | 19.881 | 7 | 9 | 12 | 9 | 1312 | 153.8 | 6.89 | | 9 | 1 | 1 | | 10 | 1 | 1 | 6431388.984 | 13079996.78 | 7620052.578 | 10886942.4 | 6 | 9 | 8 | 5 | | cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus | chromosome;membrane;nucleus | catalytic activity;DNA binding;metal ion binding;nucleotide binding;protein binding | "Pf02463, Pf04423, Pf13304, Pf13476, Pf13514, Pf13555, Pf13558" | 10111 | ENSG00000113522.13 | RAD50 | 5 | G2/M DNA damage checkpoint; Presynaptic phase of homologous DNA pairing and strand exchange; Nonhomologous End-Joining (NHEJ); Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Meiotic recombination; Sensing of DNA Double Strand Breaks; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; HDR through Single Strand Annealing (SSA); HDR through MMEJ (alt-NHEJ); DNA Damage/Telomere Stress Induced Senescence; Regulation of TP53 Activity through Phosphorylation; Resolution of D-loop Structures through Holliday Junction Intermediates | Homologous recombination; Non-homologous end-joining | 0 |