Protein FDR Confidence: CombinedAccessionDescriptionExp. q-value: CombinedSum PEP ScoreCoverage [%]# Peptides# PSMs# Unique Peptides# AAsMW [kDa]calc. pI# Peptides (by Search Engine): A2 Sequest HT (IgG)# Peptides (by Search Engine): B2 Sequest HT (Sel1L)# Peptides (by Search Engine): C2 Sequest HT (WT)# Peptides (by Search Engine): D2 Sequest HT (HKO)# PSMs (by Search Engine): A2 Sequest HT (IgG)# PSMs (by Search Engine): B2 Sequest HT (Sel1L)# PSMs (by Search Engine): C2 Sequest HT (WT)# PSMs (by Search Engine): D2 Sequest HT (HKO)Abundance: F1: Sample, IgGAbundance: F2: Sample, Sel1LAbundance: F3: Sample, WTAbundance: F4: Sample, HKOAbundances Count: F1: Sample, IgGAbundances Count: F2: Sample, Sel1LAbundances Count: F3: Sample, WTAbundances Count: F4: Sample, HKOModificationsBiological ProcessCellular ComponentMolecular FunctionPfam IDsEntrez Gene IDEnsembl Gene IDGene SymbolChromosomeReactome PathwaysKEGG Pathways# Razor Peptides
HighP04637Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4010.23213611639343.66.79413241422823827.9063407042.1883171369.6252664242.4386666cell communication;cell death;cell differentiation;cell organization and biogenesis;cell proliferation;development;metabolic process;regulation of biological process;response to stimuluscytoplasm;cytosol;endoplasmic reticulum;mitochondrion;nucleus;organelle lumencatalytic activity;DNA binding;metal ion binding;nucleotide binding;protein binding;RNA binding"Pf00870, Pf07710, Pf08563"7157ENSG00000141510.16TP5317TP53 Regulates Transcription of Caspase Activators and Caspases; TP53 Regulates Transcription of Death Receptors and Ligands; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Ovarian tumor domain proteases; TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain; Factors involved in megakaryocyte development and platelet production; Activation of PUMA and translocation to mitochondria; TP53 Regulates Transcription of DNA Repair Genes; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; SUMOylation of transcription factors; Regulation of TP53 Expression; Regulation of TP53 Activity through Phosphorylation; Transcriptional activation of cell cycle inhibitor p21 ; Pre-NOTCH Transcription and Translation; The role of GTSE1 in G2/M progression after G2 checkpoint; G2/M DNA damage checkpoint; Ub-specific processing proteases; PI5P Regulates TP53 Acetylation; Regulation of TP53 Activity through Association with Co-factors; Regulation of TP53 Degradation; Regulation of TP53 Activity through Methylation; Activation of NOXA and translocation to mitochondria; Association of TriC/CCT with target proteins during biosynthesis; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of PTEN gene transcription; TP53 Regulates Metabolic Genes; Oncogene Induced Senescence; Interleukin-4 and 13 signaling; Formation of Senescence-Associated Heterochromatin Foci (SAHF); TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; Oxidative Stress Induced Senescence; RUNX3 regulates CDKN1A transcriptionViral carcinogenesis; Hepatitis B; Central carbon metabolism in cancer; Pancreatic cancer; MicroRNAs in cancer; Chronic myeloid leukemia; Epstein-Barr virus infection; Neurotrophin signaling pathway; Huntington's disease; Non-small cell lung cancer; MAPK signaling pathway; Endometrial cancer; Breast cancer; Colorectal cancer; Pathways in cancer; Prostate cancer; Thyroid hormone signaling pathway; Glioma; Melanoma; HTLV-I infection; Apoptosis; Wnt signaling pathway; Proteoglycans in cancer; Transcriptional misregulation in cancer; p53 signaling pathway; Sphingolipid signaling pathway; Measles; Small cell lung cancer; Bladder cancer; Herpes simplex infection; Amyotrophic lateral sclerosis (ALS); Thyroid cancer; Hepatitis C; Cell cycle; Endocrine resistance; Basal cell carcinoma; Longevity regulating pathway; PI3K-Akt signaling pathway; Platinum drug resistance0

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