High | P09429 | High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1 PE=1 SV=3 | 0 | 4.027 | 13 | 2 | 4 | 2 | 215 | 24.9 | 5.74 | 1 | 1 | | 2 | 1 | 1 | | 2 | 237380.5938 | 232373.875 | 364519.7813 | 372980.5469 | 1 | 1 | 1 | 2 | | cell differentiation;cell organization and biogenesis;cell proliferation;cellular component movement;cellular homeostasis;defense response;metabolic process;regulation of biological process;response to stimulus;transport | cell surface;chromosome;cytoplasm;endosome;extracellular;membrane;nucleus;organelle lumen | catalytic activity;DNA binding;enzyme regulator activity;protein binding;RNA binding | "Pf00505, Pf09011" | 3146 | ENSG00000189403.14 | HMGB1 | 13 | TRAF6 mediated NF-kB activation; Advanced glycosylation endproduct receptor signaling; TAK1 activates NFkB by phosphorylation and activation of IKKs complex; RIP-mediated NFkB activation via ZBP1; Activated TLR4 signalling; Interleukin-1 family signaling; Neutrophil degranulation; Regulation of TLR by endogenous ligand; DEx/H-box helicases activate type I IFN and inflammatory cytokines production ; Activation of DNA fragmentation factor | Base excision repair | 0 |