Protein FDR Confidence: Combined | Accession | Description | Exp. q-value: Combined | Sum PEP Score | Coverage [%] | # Peptides | # PSMs | # Unique Peptides | # AAs | MW [kDa] | calc. pI | # Peptides (by Search Engine): A2 Sequest HT (IgG) | # Peptides (by Search Engine): B2 Sequest HT (Sel1L) | # Peptides (by Search Engine): C2 Sequest HT (WT) | # Peptides (by Search Engine): D2 Sequest HT (HKO) | # PSMs (by Search Engine): A2 Sequest HT (IgG) | # PSMs (by Search Engine): B2 Sequest HT (Sel1L) | # PSMs (by Search Engine): C2 Sequest HT (WT) | # PSMs (by Search Engine): D2 Sequest HT (HKO) | Abundance: F1: Sample, IgG | Abundance: F2: Sample, Sel1L | Abundance: F3: Sample, WT | Abundance: F4: Sample, HKO | Abundances Count: F1: Sample, IgG | Abundances Count: F2: Sample, Sel1L | Abundances Count: F3: Sample, WT | Abundances Count: F4: Sample, HKO | Modifications | Biological Process | Cellular Component | Molecular Function | Pfam IDs | Entrez Gene ID | Ensembl Gene ID | Gene Symbol | Chromosome | Reactome Pathways | KEGG Pathways | # Razor Peptides |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
High | P09874 | Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 | 0 | 92.139 | 37 | 28 | 66 | 28 | 1014 | 113 | 8.88 | 1 | 25 | 14 | 9 | 1 | 38 | 17 | 10 | 607659.9961 | 45188940.81 | 14264696.16 | 9453122.352 | 7 | 25 | 22 | 18 | Met-loss+Acetyl [N-Term] | cell death;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus | membrane;mitochondrion;nucleus | catalytic activity;DNA binding;metal ion binding;nucleotide binding;protein binding;RNA binding | "Pf00533, Pf00644, Pf00645, Pf02877, Pf05406, Pf08063" | 142 | ENSG00000143799.12 | PARP1 | 1 | POLB-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Formation of Incision Complex in GG-NER; Downregulation of SMAD2/3:SMAD4 transcriptional activity; DNA Damage Recognition in GG-NER; HDR through MMEJ (alt-NHEJ); SUMOylation of DNA damage response and repair proteins | Base excision repair; NF-kappa B signaling pathway; Apoptosis | 0 |