High | P24941 | Cyclin-dependent kinase 2 OS=Homo sapiens OX=9606 GN=CDK2 PE=1 SV=2 | 0 | 4.307 | 6 | 2 | 3 | 1 | 298 | 33.9 | 8.68 | 1 | | 1 | | 2 | | 1 | | 1052568.875 | 1084912.438 | 1306399.906 | 1139582.75 | 1 | 2 | 2 | 1 | | cell division;cell organization and biogenesis;development;metabolic process;regulation of biological process;response to stimulus;transport | chromosome;cytoplasm;cytoskeleton;cytosol;endosome;nucleus | catalytic activity;metal ion binding;nucleotide binding;protein binding | "Pf00069, Pf07714, Pf14531" | 1017 | ENSG00000123374.10 | CDK2 | 12 | p53-Dependent G1 DNA Damage Response; G0 and Early G1; Regulation of DNA replication; Activation of the pre-replicative complex; TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; SCF(Skp2)-mediated degradation of p27/p21; Factors involved in megakaryocyte development and platelet production; G2 Phase; Meiotic recombination; Regulation of APC/C activators between G1/S and early anaphase; PTK6 Regulates Cell Cycle; Regulation of TP53 Activity through Phosphorylation; Regulation of TP53 Degradation; CDK-mediated phosphorylation and removal of Cdc6; Orc1 removal from chromatin; Cyclin A/B1/B2 associated events during G2/M transition; M/G1 Transition; Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes; Activation of ATR in response to replication stress; Processing of DNA double-strand break ends; DNA Damage/Telomere Stress Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); Removal of licensing factors from origins | Viral carcinogenesis; Hepatitis B; FoxO signaling pathway; Epstein-Barr virus infection; Progesterone-mediated oocyte maturation; Pathways in cancer; Prostate cancer; p53 signaling pathway; Oocyte meiosis; Measles; Small cell lung cancer; Herpes simplex infection; Cell cycle; PI3K-Akt signaling pathway | 1 |