Protein FDR Confidence: Combined	Accession	Description	Exp. q-value: Combined	Sum PEP Score	Coverage [%]	# Peptides	# PSMs	# Unique Peptides	# AAs	MW [kDa]	calc. pI	# Peptides (by Search Engine): A2 Sequest HT (IgG)	# Peptides (by Search Engine): B2 Sequest HT (Sel1L)	# Peptides (by Search Engine): C2 Sequest HT (WT)	# Peptides (by Search Engine): D2 Sequest HT (HKO)	# PSMs (by Search Engine): A2 Sequest HT (IgG)	# PSMs (by Search Engine): B2 Sequest HT (Sel1L)	# PSMs (by Search Engine): C2 Sequest HT (WT)	# PSMs (by Search Engine): D2 Sequest HT (HKO)	Abundance: F1: Sample, IgG	Abundance: F2: Sample, Sel1L	Abundance: F3: Sample, WT	Abundance: F4: Sample, HKO	Abundances Count: F1: Sample, IgG	Abundances Count: F2: Sample, Sel1L	Abundances Count: F3: Sample, WT	Abundances Count: F4: Sample, HKO	Modifications	Biological Process	Cellular Component	Molecular Function	Pfam IDs	Entrez Gene ID	Ensembl Gene ID	Gene Symbol	Chromosome	Reactome Pathways	KEGG Pathways	# Razor Peptides
High	P60900	Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6 PE=1 SV=1	0.003	2.411	5	1	1	1	246	27.4	6.76				1				1		277079.375	240876.1875	666767.6875		1	1	1		metabolic process;regulation of biological process;response to stimulus;transport	cytoplasm;cytosol;nucleus;proteasome	catalytic activity;nucleotide binding;protein binding;RNA binding	"Pf00227, Pf10584"	5687	ENSG00000100902.10	PSMA6	14	Regulation of RAS by GAPs; CDT1 association with the CDC6:ORC:origin complex; Downstream TCR signaling; UCH proteinases; NIK-->noncanonical NF-kB signaling; Hh mutants that don't undergo autocatalytic processing are degraded by ERAD; SCF-beta-TrCP mediated degradation of Emi1; Cross-presentation of soluble exogenous antigens (endosomes); Separation of Sister Chromatids; Vpu mediated degradation of CD4; Hedgehog ligand biogenesis; Regulation of RUNX2 expression and activity; Ub-specific processing proteases; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; ER-Phagosome pathway; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; ABC-family proteins mediated transport; Regulation of activated PAK-2p34 by proteasome mediated degradation; CDK-mediated phosphorylation and removal of Cdc6; FCERI mediated NF-kB activation; Neddylation; Autodegradation of the E3 ubiquitin ligase COP1; G2/M Checkpoints; Regulation of RUNX3 expression and activity; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Regulation of expression of SLITs and ROBOs; Removal of licensing factors from origins; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of PTEN stability and activity; Regulation of DNA replication; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Antigen processing: Ubiquitination & Proteasome degradation; GLI3 is processed to GLI3R by the proteasome; SCF(Skp2)-mediated degradation of p27/p21; APC/C:Cdc20 mediated degradation of Securin; Interleukin-1 family signaling; AUF1 (hnRNP D0) binds and destabilizes mRNA; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of ornithine decarboxylase (ODC); Interleukin-20 family signaling; Hedgehog 'on' state; Ubiquitin-dependent degradation of Cyclin D1; Degradation of DVL; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Degradation of AXIN; Autodegradation of Cdh1 by Cdh1:APC/C; Asymmetric localization of PCP proteins; Orc1 removal from chromatin; M/G1 Transition; Activation of NF-kappaB in B cells; Degradation of beta-catenin by the destruction complex; MAPK6/MAPK4 signaling; Dectin-1 mediated noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis	Proteasome	0

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