High | P62714 | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform OS=Homo sapiens OX=9606 GN=PPP2CB PE=1 SV=1 | 0 | 4.697 | 6 | 2 | 3 | 2 | 309 | 35.6 | 5.43 | | 2 | 1 | | | 2 | 1 | | | 988112.3125 | 1406653.063 | 2011595.313 | | 2 | 2 | 2 | | cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus | chromosome;cytoplasm;cytoskeleton;cytosol;nucleus | catalytic activity;metal ion binding;protein binding | Pf00149 | 5516 | ENSG00000104695.12 | PPP2CB | 8 | "Glycolysis; AXIN missense mutants destabilize the destruction complex; PP2A-mediated dephosphorylation of key metabolic factors; APC truncation mutants have impaired AXIN binding; CTLA4 inhibitory signaling; Activated TLR4 signalling; Separation of Sister Chromatids; MASTL Facilitates Mitotic Progression; S37 mutants of beta-catenin aren't phosphorylated; S33 mutants of beta-catenin aren't phosphorylated; S45 mutants of beta-catenin aren't phosphorylated; Misspliced GSK3beta mutants stabilize beta-catenin; Cyclin A/B1/B2 associated events during G2/M transition; T41 mutants of beta-catenin aren't phosphorylated; RAF activation; ERKs are inactivated; Beta-catenin phosphorylation cascade; Negative regulation of MAPK pathway; Platelet sensitization by LDL; Signaling by GPCR; Interleukin-20 family signaling; Spry regulation of FGF signaling; DARPP-32 events; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Regulation of TP53 Degradation; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Cyclin D associated events in G1; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; Truncations of AMER1 destabilize the destruction complex" | Dopaminergic synapse; Chagas disease (American trypanosomiasis); TGF-beta signaling pathway; Tight junction; Hippo signaling pathway; Adrenergic signaling in cardiomyocytes; AMPK signaling pathway; Long-term depression; mRNA surveillance pathway; Oocyte meiosis; Sphingolipid signaling pathway; Hepatitis C; PI3K-Akt signaling pathway | 0 |