High | P62877 | E3 ubiquitin-protein ligase RBX1 OS=Homo sapiens OX=9606 GN=RBX1 PE=1 SV=1 | 0 | 18.905 | 26 | 3 | 14 | 3 | 108 | 12.3 | 6.96 | | 3 | 2 | 3 | | 4 | 4 | 6 | 1290051.344 | 6894771 | 7735787.188 | 8460707.625 | 2 | 3 | 3 | 3 | Met-loss+Acetyl [N-Term] | cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus | cytoplasm;cytosol;nucleus | catalytic activity;metal ion binding;protein binding | "Pf00097, Pf12678, Pf12861, Pf13639" | 9978 | ENSG00000100387.8 | RBX1 | 22 | FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; NOTCH1 Intracellular Domain Regulates Transcription; Regulation of RAS by GAPs; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Antigen processing: Ubiquitination & Proteasome degradation; GLI3 is processed to GLI3R by the proteasome; Interleukin-1 family signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; Interleukin-20 family signaling; Regulation of RUNX2 expression and activity; Hedgehog 'on' state; Gap-filling DNA repair synthesis and ligation in TC-NER; Degradation of DVL; Formation of TC-NER Pre-Incision Complex; Dual Incision in GG-NER; Prolactin receptor signaling; Neddylation; Degradation of beta-catenin by the destruction complex; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling; Dual incision in TC-NER; Regulation of expression of SLITs and ROBOs | TGF-beta signaling pathway; HIF-1 signaling pathway; Ubiquitin mediated proteolysis; Pathways in cancer; Protein processing in endoplasmic reticulum; Renal cell carcinoma; Nucleotide excision repair; Wnt signaling pathway; Oocyte meiosis; Circadian rhythm; Cell cycle | 0 |