Protein FDR Confidence: Combined	Accession	Description	Exp. q-value: Combined	Sum PEP Score	Coverage [%]	# Peptides	# PSMs	# Unique Peptides	# AAs	MW [kDa]	calc. pI	# Peptides (by Search Engine): A2 Sequest HT (IgG)	# Peptides (by Search Engine): B2 Sequest HT (Sel1L)	# Peptides (by Search Engine): C2 Sequest HT (WT)	# Peptides (by Search Engine): D2 Sequest HT (HKO)	# PSMs (by Search Engine): A2 Sequest HT (IgG)	# PSMs (by Search Engine): B2 Sequest HT (Sel1L)	# PSMs (by Search Engine): C2 Sequest HT (WT)	# PSMs (by Search Engine): D2 Sequest HT (HKO)	Abundance: F1: Sample, IgG	Abundance: F2: Sample, Sel1L	Abundance: F3: Sample, WT	Abundance: F4: Sample, HKO	Abundances Count: F1: Sample, IgG	Abundances Count: F2: Sample, Sel1L	Abundances Count: F3: Sample, WT	Abundances Count: F4: Sample, HKO	Modifications	Biological Process	Cellular Component	Molecular Function	Pfam IDs	Entrez Gene ID	Ensembl Gene ID	Gene Symbol	Chromosome	Reactome Pathways	KEGG Pathways	# Razor Peptides
High	Q13547	Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1	0.004	2.274	4	1	1	1	482	55.1	5.48				1				1	400847.7188	223783.7969	443242.0313	594796.5625	1	1	1	1		cell differentiation;cell organization and biogenesis;coagulation;metabolic process;regulation of biological process	chromosome;cytoplasm;cytosol;nucleus	catalytic activity;DNA binding;metal ion binding;protein binding	Pf00850	3065	ENSG00000116478.11	HDAC1	1	NOTCH1 Intracellular Domain Regulates Transcription; NoRC negatively regulates rRNA expression; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Factors involved in megakaryocyte development and platelet production; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Downregulation of SMAD2/3:SMAD4 transcriptional activity; Activation of E2F1 target genes at G1/S; HDACs deacetylate histones; Formation of the beta-catenin:TCF transactivating complex; Transcription of E2F targets under negative control by DREAM complex; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Regulation of TP53 Activity through Acetylation; Repression of WNT target genes; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; SUMOylation of chromatin organization proteins; Deactivation of the beta-catenin transactivating complex; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of PTEN gene transcription; Constitutive Signaling by NOTCH1 PEST Domain Mutants; p75NTR negatively regulates cell cycle via SC1; Signalling by NGF; RNA Polymerase I Transcription Initiation	Viral carcinogenesis; Longevity regulating pathway - multiple species; MicroRNAs in cancer; Amphetamine addiction; Chronic myeloid leukemia; Epstein-Barr virus infection; Huntington's disease; Pathways in cancer; Thyroid hormone signaling pathway; Transcriptional misregulation in cancer; Notch signaling pathway; Alcoholism; Cell cycle	0

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