High | Q13616 | Cullin-1 OS=Homo sapiens OX=9606 GN=CUL1 PE=1 SV=2 | 0 | 181.311 | 52 | 38 | 171 | 38 | 776 | 89.6 | 8 | | 31 | 31 | 36 | | 57 | 54 | 60 | 1031148.047 | 97406179.63 | 113560127.8 | 140748940.8 | 8 | 36 | 36 | 38 | | cell death;cell organization and biogenesis;cell proliferation;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus | cytosol | catalytic activity;protein binding | "Pf00888, Pf10557" | 8454 | ENSG00000055130.15 | CUL1 | 7 | FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; NOTCH1 Intracellular Domain Regulates Transcription; Downstream TCR signaling; Regulation of PLK1 Activity at G2/M Transition; NIK-->noncanonical NF-kB signaling; MAP3K8 (TPL2)-dependent MAPK1/3 activation; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Antigen processing: Ubiquitination & Proteasome degradation; Iron uptake and transport; GLI3 is processed to GLI3R by the proteasome; SCF(Skp2)-mediated degradation of p27/p21; Activated TLR4 signalling; Interleukin-1 family signaling; Degradation of GLI1 by the proteasome; SCF-beta-TrCP mediated degradation of Emi1; Degradation of GLI2 by the proteasome; Regulation of RUNX2 expression and activity; Cyclin D associated events in G1; Prolactin receptor signaling; FCERI mediated NF-kB activation; Neddylation; Circadian Clock; Activation of NF-kappaB in B cells; Degradation of beta-catenin by the destruction complex; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling; Dectin-1 mediated noncanonical NF-kB signaling | TGF-beta signaling pathway; Ubiquitin mediated proteolysis; Protein processing in endoplasmic reticulum; Wnt signaling pathway; Oocyte meiosis; Hedgehog signaling pathway; Circadian rhythm; Herpes simplex infection; Cell cycle | 0 |