Protein FDR Confidence: CombinedAccessionDescriptionExp. q-value: CombinedSum PEP ScoreCoverage [%]# Peptides# PSMs# Unique Peptides# AAsMW [kDa]calc. pI# Peptides (by Search Engine): A2 Sequest HT (IgG)# Peptides (by Search Engine): B2 Sequest HT (Sel1L)# Peptides (by Search Engine): C2 Sequest HT (WT)# Peptides (by Search Engine): D2 Sequest HT (HKO)# PSMs (by Search Engine): A2 Sequest HT (IgG)# PSMs (by Search Engine): B2 Sequest HT (Sel1L)# PSMs (by Search Engine): C2 Sequest HT (WT)# PSMs (by Search Engine): D2 Sequest HT (HKO)Abundance: F1: Sample, IgGAbundance: F2: Sample, Sel1LAbundance: F3: Sample, WTAbundance: F4: Sample, HKOAbundances Count: F1: Sample, IgGAbundances Count: F2: Sample, Sel1LAbundances Count: F3: Sample, WTAbundances Count: F4: Sample, HKOModificationsBiological ProcessCellular ComponentMolecular FunctionPfam IDsEntrez Gene IDEnsembl Gene IDGene SymbolChromosomeReactome PathwaysKEGG Pathways# Razor Peptides
HighQ86TM6E3 ubiquitin-protein ligase synoviolin OS=Homo sapiens OX=9606 GN=SYVN1 PE=1 SV=2034.6211411341161767.66.951162311904368.648485010284.2517889207.9721210metabolic process;regulation of biological process;response to stimulus;transportendoplasmic reticulum;membranecatalytic activity;metal ion binding;protein binding"Pf00097, Pf12678, Pf12861, Pf12906, Pf13445, Pf13639, Pf13920, Pf13923, Pf14634"84447ENSG00000162298.18SYVN111Hh mutants that don't undergo autocatalytic processing are degraded by ERAD; ER Quality Control Compartment (ERQC); XBP1(S) activates chaperone genes; Hedgehog ligand biogenesisUbiquitin mediated proteolysis; Protein processing in endoplasmic reticulum0

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