Protein FDR Confidence: CombinedAccessionDescriptionExp. q-value: CombinedSum PEP ScoreCoverage [%]# Peptides# PSMs# Unique Peptides# AAsMW [kDa]calc. pI# Peptides (by Search Engine): A2 Sequest HT (IgG)# Peptides (by Search Engine): B2 Sequest HT (Sel1L)# Peptides (by Search Engine): C2 Sequest HT (WT)# Peptides (by Search Engine): D2 Sequest HT (HKO)# PSMs (by Search Engine): A2 Sequest HT (IgG)# PSMs (by Search Engine): B2 Sequest HT (Sel1L)# PSMs (by Search Engine): C2 Sequest HT (WT)# PSMs (by Search Engine): D2 Sequest HT (HKO)Abundance: F1: Sample, IgGAbundance: F2: Sample, Sel1LAbundance: F3: Sample, WTAbundance: F4: Sample, HKOAbundances Count: F1: Sample, IgGAbundances Count: F2: Sample, Sel1LAbundances Count: F3: Sample, WTAbundances Count: F4: Sample, HKOModificationsBiological ProcessCellular ComponentMolecular FunctionPfam IDsEntrez Gene IDEnsembl Gene IDGene SymbolChromosomeReactome PathwaysKEGG Pathways# Razor Peptides
HighQ92542Nicastrin OS=Homo sapiens OX=9606 GN=NCSTN PE=1 SV=204.215211170978.45.9911cell proliferation;metabolic process;regulation of biological process;response to stimulus;transportendoplasmic reticulum;Golgi;membranecatalytic activity;protein bindingPf0545023385ENSG00000162736.15NCSTN1Activated NOTCH1 Transmits Signal to the Nucleus; Signaling by NOTCH4; Regulated proteolysis of p75NTR; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NRIF signals cell death from the nucleus; Signaling by NOTCH3; EPH-ephrin mediated repulsion of cells; NOTCH2 Activation and Transmission of Signal to the Nucleus; Degradation of the extracellular matrix; Neutrophil degranulation; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Nuclear signaling by ERBB4; Signalling by NGFAlzheimer's disease; Notch signaling pathway0

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