Protein FDR Confidence: Combined	Accession	Description	Exp. q-value: Combined	Sum PEP Score	Coverage [%]	# Peptides	# PSMs	# Unique Peptides	# AAs	MW [kDa]	calc. pI	# Peptides (by Search Engine): A2 Sequest HT (IgG)	# Peptides (by Search Engine): B2 Sequest HT (SKO)	# Peptides (by Search Engine): C2 Sequest HT (WT)	# Peptides (by Search Engine): D2 Sequest HT (HKO)	# PSMs (by Search Engine): A2 Sequest HT (IgG)	# PSMs (by Search Engine): B2 Sequest HT (SKO)	# PSMs (by Search Engine): C2 Sequest HT (WT)	# PSMs (by Search Engine): D2 Sequest HT (HKO)	Abundance: F1: Sample, IgG	Abundance: F2: Sample, SKO	Abundance: F3: Sample, WT	Abundance: F4: Sample, HKO	Abundances Count: F1: Sample, IgG	Abundances Count: F2: Sample, SKO	Abundances Count: F3: Sample, WT	Abundances Count: F4: Sample, HKO	Modifications	Biological Process	Cellular Component	Molecular Function	Pfam IDs	Entrez Gene ID	Ensembl Gene ID	Gene Symbol	Chromosome	Reactome Pathways	KEGG Pathways	# Razor Peptides
High	Q8C863	E3 ubiquitin-protein ligase Itchy OS=Mus musculus OX=10090 GN=Itch PE=1 SV=2	0.004	2.528	1	1	1	1	864	98.9	6.28	1				1				1443162.75		1309859.625		1		1			cell death;defense response;metabolic process;regulation of biological process;response to stimulus	cytoplasm;cytosol;endosome;membrane;nucleus	catalytic activity;protein binding	"Pf00168, Pf00397, Pf00632"	16396	ENSMUSG00000027598.16	Itch	2	Activated NOTCH1 Transmits Signal to the Nucleus; Hedgehog 'on' state; Downregulation of ERBB4 signaling; Degradation of GLI1 by the proteasome; NOD1/2 Signaling Pathway; RUNX1 regulates transcription of genes involved in differentiation of HSCs	Endocytosis; Ubiquitin mediated proteolysis; TNF signaling pathway; Non-alcoholic fatty liver disease (NAFLD)	0

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