Protein FDR Confidence: CombinedAccessionDescriptionExp. q-value: CombinedSum PEP ScoreCoverage [%]# Peptides# PSMs# Unique Peptides# AAsMW [kDa]calc. pI# Peptides (by Search Engine): A2 Sequest HT (293 IgG)# Peptides (by Search Engine): B2 Sequest HT (293 Sel1L KO)# Peptides (by Search Engine): C2 Sequest HT (293 WT)# Peptides (by Search Engine): D2 Sequest HT (293 H KO)# PSMs (by Search Engine): A2 Sequest HT (293 IgG)# PSMs (by Search Engine): B2 Sequest HT (293 Sel1L KO)# PSMs (by Search Engine): C2 Sequest HT (293 WT)# PSMs (by Search Engine): D2 Sequest HT (293 H KO)Abundance: F1: Sample, 293 IgGAbundance: F2: Sample, 293 Sel1L KOAbundance: F3: Sample, 293 WTAbundance: F4: Sample, 293 H KOAbundances Count: F1: Sample, 293 IgGAbundances Count: F2: Sample, 293 Sel1L KOAbundances Count: F3: Sample, 293 WTAbundances Count: F4: Sample, 293 H KOModificationsBiological ProcessCellular ComponentMolecular FunctionPfam IDsEntrez Gene IDEnsembl Gene IDGene SymbolChromosomeReactome PathwaysKEGG Pathways# Razor Peptides
MediumP27986Phosphatidylinositol 3-kinase regulatory subunit alpha OS=Homo sapiens OX=9606 GN=PIK3R1 PE=1 SV=20.0481.131411172483.56.1611cell death;cell differentiation;cellular component movement;cellular homeostasis;defense response;metabolic process;regulation of biological process;response to stimulus;transportcytoplasm;cytosol;membrane;nucleuscatalytic activity;enzyme regulator activity;nucleotide binding;protein binding"Pf00017, Pf00018, Pf00620"5295ENSG00000145675.14PIK3R15"PI3K Cascade; Signaling by FGFR4 in disease; Downstream TCR signaling; PI-3K cascade:FGFR3; PI3K events in ERBB4 signaling; DAP12 signaling; PI-3K cascade:FGFR4; Regulation of signaling by CBL; Signaling by cytosolic FGFR1 fusion mutants; MET activates PI3K/AKT signaling; Role of phospholipids in phagocytosis; G alpha (12/13) signalling events; Constitutive Signaling by EGFRvIII; VEGFA-VEGFR2 Pathway; Interleukin receptor SHC signaling; GPVI-mediated activation cascade; CD28 dependent PI3K/Akt signaling; PI-3K cascade:FGFR2; RET signaling; Synthesis of PIPs at the plasma membrane; PI3K events in ERBB2 signaling; PI-3K cascade:FGFR1; Interleukin-4 and 13 signaling; Role of LAT2/NTAL/LAB on calcium mobilization; Tie2 Signaling; Signaling by FGFR2 in disease; Signaling by FGFR3 fusions in cancer; G beta:gamma signalling through PI3Kgamma; Interleukin-7 signaling; Downstream signal transduction; GP1b-IX-V activation signalling; Signaling by FGFR3 point mutants in cancer; PI3K/AKT activation; Nephrin family interactions; Constitutive Signaling by Aberrant PI3K in Cancer; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Gastrin-CREB signalling pathway via PKC and MAPK; Signaling by SCF-KIT; GAB1 signalosome"Viral carcinogenesis; Chagas disease (American trypanosomiasis); Longevity regulating pathway - multiple species; Amoebiasis; T cell receptor signaling pathway; TNF signaling pathway; Osteoclast differentiation; Hepatitis B; Insulin signaling pathway; HIF-1 signaling pathway; Central carbon metabolism in cancer; Pancreatic cancer; FoxO signaling pathway; Prolactin signaling pathway; Phospholipase D signaling pathway; cGMP-PKG signaling pathway; Chronic myeloid leukemia; Epstein-Barr virus infection; Neurotrophin signaling pathway; B cell receptor signaling pathway; VEGF signaling pathway; Acute myeloid leukemia; Rap1 signaling pathway; Non-small cell lung cancer; Progesterone-mediated oocyte maturation; Oxytocin signaling pathway; Endometrial cancer; Breast cancer; Colorectal cancer; Type II diabetes mellitus; Natural killer cell mediated cytotoxicity; ErbB signaling pathway; Pathways in cancer; Prostate cancer; Thyroid hormone signaling pathway; Glioma; Phosphatidylinositol signaling system; Adrenergic signaling in cardiomyocytes; AGE-RAGE signaling pathway in diabetic complications; Renal cell carcinoma; Melanoma; EGFR tyrosine kinase inhibitor resistance; HTLV-I infection; Toxoplasmosis; Apoptosis; Focal adhesion; Jak-STAT signaling pathway; Proteoglycans in cancer; Choline metabolism in cancer; AMPK signaling pathway; mTOR signaling pathway; Aldosterone-regulated sodium reabsorption; Carbohydrate digestion and absorption; Regulation of actin cytoskeleton; Leukocyte transendothelial migration; Non-alcoholic fatty liver disease (NAFLD); Sphingolipid signaling pathway; Bacterial invasion of epithelial cells; Measles; Small cell lung cancer; Toll-like receptor signaling pathway; Fc epsilon RI signaling pathway; Inflammatory mediator regulation of TRP channels; Hepatitis C; Ras signaling pathway; Fc gamma R-mediated phagocytosis; Endocrine resistance; Chemokine signaling pathway; Axon guidance; Signaling pathways regulating pluripotency of stem cells; cAMP signaling pathway; Influenza A; Estrogen signaling pathway; Regulation of lipolysis in adipocytes; Insulin resistance; Cholinergic synapse; Longevity regulating pathway; PI3K-Akt signaling pathway; Platelet activation; Platinum drug resistance0

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