Protein FDR Confidence: CombinedAccessionDescriptionExp. q-value: CombinedSum PEP ScoreCoverage [%]# Peptides# PSMs# Unique Peptides# AAsMW [kDa]calc. pI# Peptides (by Search Engine): A2 Sequest HT (IgG 293)# Peptides (by Search Engine): B2 Sequest HT (HKO 293)# Peptides (by Search Engine): C2 Sequest HT (SKO 293)# Peptides (by Search Engine): D2 Sequest HT (WT 293)# PSMs (by Search Engine): A2 Sequest HT (IgG 293)# PSMs (by Search Engine): B2 Sequest HT (HKO 293)# PSMs (by Search Engine): C2 Sequest HT (SKO 293)# PSMs (by Search Engine): D2 Sequest HT (WT 293)Abundance: F5: Sample, IgG 293Abundance: F6: Sample, HKO 293Abundance: F7: Sample, SKO 293Abundance: F8: Sample, WT 203Abundances Count: F5: Sample, IgG 293Abundances Count: F6: Sample, HKO 293Abundances Count: F7: Sample, SKO 293Abundances Count: F8: Sample, WT 203ModificationsBiological ProcessCellular ComponentMolecular FunctionPfam IDsEntrez Gene IDEnsembl Gene IDGene SymbolChromosomeReactome PathwaysKEGG Pathways# Razor Peptides
HighP22681E3 ubiquitin-protein ligase CBL OS=Homo sapiens OX=9606 GN=CBL PE=1 SV=209.406549490699.66.5431242332222.378912126476.7811206528.5781268082.9061444cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transportcytoplasm;cytosol;membrane;nucleus;vacuolecatalytic activity;metal ion binding;protein binding;signal transducer activity"Pf00097, Pf00627, Pf02262, Pf02761, Pf02762, Pf13639, Pf13920, Pf13923, Pf14447, Pf14634, Pf15227"867ENSG00000110395.6CBL11Spry regulation of FGF signaling; Cargo recognition for clathrin-mediated endocytosis; TGF-beta receptor signaling activates SMADs; Constitutive Signaling by EGFRvIII; PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1; EGFR downregulation; Negative regulation of MET activity; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Regulation of signaling by CBL; Regulation of KIT signaling; Interleukin-6 family signaling; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; InlB-mediated entry of Listeria monocytogenes into host cellEndocytosis; T cell receptor signaling pathway; Insulin signaling pathway; Ubiquitin mediated proteolysis; Chronic myeloid leukemia; ErbB signaling pathway; Pathways in cancer; Proteoglycans in cancer; Bacterial invasion of epithelial cells0

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