High | P22681 | E3 ubiquitin-protein ligase CBL OS=Homo sapiens OX=9606 GN=CBL PE=1 SV=2 | 0 | 9.406 | 5 | 4 | 9 | 4 | 906 | 99.6 | 6.54 | | 3 | 1 | 2 | | 4 | 2 | 3 | 32222.37891 | 2126476.781 | 1206528.578 | 1268082.906 | 1 | 4 | 4 | 4 | | cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport | cytoplasm;cytosol;membrane;nucleus;vacuole | catalytic activity;metal ion binding;protein binding;signal transducer activity | "Pf00097, Pf00627, Pf02262, Pf02761, Pf02762, Pf13639, Pf13920, Pf13923, Pf14447, Pf14634, Pf15227" | 867 | ENSG00000110395.6 | CBL | 11 | Spry regulation of FGF signaling; Cargo recognition for clathrin-mediated endocytosis; TGF-beta receptor signaling activates SMADs; Constitutive Signaling by EGFRvIII; PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1; EGFR downregulation; Negative regulation of MET activity; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Regulation of signaling by CBL; Regulation of KIT signaling; Interleukin-6 family signaling; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; InlB-mediated entry of Listeria monocytogenes into host cell | Endocytosis; T cell receptor signaling pathway; Insulin signaling pathway; Ubiquitin mediated proteolysis; Chronic myeloid leukemia; ErbB signaling pathway; Pathways in cancer; Proteoglycans in cancer; Bacterial invasion of epithelial cells | 0 |