Protein FDR Confidence: CombinedAccessionDescriptionExp. q-value: CombinedSum PEP ScoreCoverage [%]# Peptides# PSMs# Unique Peptides# AAsMW [kDa]calc. pI# Peptides (by Search Engine): A2 Sequest HT (IgG 293)# Peptides (by Search Engine): B2 Sequest HT (HKO 293)# Peptides (by Search Engine): C2 Sequest HT (SKO 293)# Peptides (by Search Engine): D2 Sequest HT (WT 293)# PSMs (by Search Engine): A2 Sequest HT (IgG 293)# PSMs (by Search Engine): B2 Sequest HT (HKO 293)# PSMs (by Search Engine): C2 Sequest HT (SKO 293)# PSMs (by Search Engine): D2 Sequest HT (WT 293)Abundance: F5: Sample, IgG 293Abundance: F6: Sample, HKO 293Abundance: F7: Sample, SKO 293Abundance: F8: Sample, WT 203Abundances Count: F5: Sample, IgG 293Abundances Count: F6: Sample, HKO 293Abundances Count: F7: Sample, SKO 293Abundances Count: F8: Sample, WT 203ModificationsBiological ProcessCellular ComponentMolecular FunctionPfam IDsEntrez Gene IDEnsembl Gene IDGene SymbolChromosomeReactome PathwaysKEGG Pathways# Razor Peptides
HighP51668Ubiquitin-conjugating enzyme E2 D1 OS=Homo sapiens OX=9606 GN=UBE2D1 PE=1 SV=105.8122022114716.67.422250895.4726640198.16406292010.9063111metabolic process;regulation of biological process;response to stimuluscytoplasm;cytosolcatalytic activity;nucleotide binding;protein binding"Pf00179, Pf05773"7321ENSG00000072401.14UBE2D110"Inactivation of APC/C via direct inhibition of the APC/C complex; Downstream TCR signaling; TICAM1, RIP1-mediated IKK complex recruitment ; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; APC-Cdc20 mediated degradation of Nek2A; Ovarian tumor domain proteases; Antigen processing: Ubiquitination & Proteasome degradation; Activated TLR4 signalling; APC/C:Cdc20 mediated degradation of Securin; Separation of Sister Chromatids; Downregulation of SMAD2/3:SMAD4 transcriptional activity; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; APC/C:Cdc20 mediated degradation of Cyclin B; IKK complex recruitment mediated by RIP1; Autodegradation of Cdh1 by Cdh1:APC/C; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; FCERI mediated NF-kB activation; Neddylation; Phosphorylation of the APC/C; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Signaling by BMP; E3 ubiquitin ligases ubiquitinate target proteins; Negative regulators of DDX58/IFIH1 signaling; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Senescence-Associated Secretory Phenotype (SASP); CLEC7A (Dectin-1) signaling"Ubiquitin mediated proteolysis; Protein processing in endoplasmic reticulum0

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