Protein FDR Confidence: Combined	Accession	Description	Exp. q-value: Combined	Sum PEP Score	Coverage [%]	# Peptides	# PSMs	# Unique Peptides	# AAs	MW [kDa]	calc. pI	# Peptides (by Search Engine): A2 Sequest HT (IgG 293)	# Peptides (by Search Engine): B2 Sequest HT (HKO 293)	# Peptides (by Search Engine): C2 Sequest HT (SKO 293)	# Peptides (by Search Engine): D2 Sequest HT (WT 293)	# PSMs (by Search Engine): A2 Sequest HT (IgG 293)	# PSMs (by Search Engine): B2 Sequest HT (HKO 293)	# PSMs (by Search Engine): C2 Sequest HT (SKO 293)	# PSMs (by Search Engine): D2 Sequest HT (WT 293)	Abundance: F5: Sample, IgG 293	Abundance: F6: Sample, HKO 293	Abundance: F7: Sample, SKO 293	Abundance: F8: Sample, WT 203	Abundances Count: F5: Sample, IgG 293	Abundances Count: F6: Sample, HKO 293	Abundances Count: F7: Sample, SKO 293	Abundances Count: F8: Sample, WT 203	Modifications	Biological Process	Cellular Component	Molecular Function	Pfam IDs	Entrez Gene ID	Ensembl Gene ID	Gene Symbol	Chromosome	Reactome Pathways	KEGG Pathways	# Razor Peptides
High	P60709	"Actin, cytoplasmic 1 OS=Homo sapiens OX=9606 GN=ACTB PE=1 SV=1"	0	51.905	50	13	62	1	375	41.7	5.48	10	10	9	13	17	13	13	19	18489776.8	13615752.54	14704053.88	23246780.15	12	11	11	12	Met-loss+Acetyl [N-Term]	cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus	cytoplasm;cytoskeleton;cytosol;membrane;nucleus	DNA binding;nucleotide binding;protein binding;structural molecule activity	Pf00022	60	ENSG00000075624.13	ACTB	7	Formation of annular gap junctions; Cell-extracellular matrix interactions; UCH proteinases; MAP2K and MAPK activation; Interaction between L1 and Ankyrins; Factors involved in megakaryocyte development and platelet production; Translocation of GLUT4 to the plasma membrane; EPH-ephrin mediated repulsion of cells; Prefoldin mediated transfer of substrate to CCT/TriC; EPHB-mediated forward signaling; Paradoxical activation of RAF signaling by kinase inactive BRAF; Folding of actin by CCT/TriC; DNA Damage Recognition in GG-NER; Regulation of actin dynamics for phagocytic cup formation; Interleukin-20 family signaling; Signaling by BRAF and RAF fusions; Clathrin-mediated endocytosis; VEGFA-VEGFR2 Pathway; HATs acetylate histones; RHO GTPases activate IQGAPs; Recycling pathway of L1; Signaling by RAS mutants; Signaling by high-kinase activity BRAF mutants; Signaling by moderate kinase activity BRAF mutants; Adherens junctions interactions; RHO GTPases Activate WASPs and WAVEs; RHO GTPases Activate Formins; B-WICH complex positively regulates rRNA expression	Arrhythmogenic right ventricular cardiomyopathy (ARVC); Tight junction; Pathogenic Escherichia coli infection; Dilated cardiomyopathy; Hippo signaling pathway; Rap1 signaling pathway; Oxytocin signaling pathway; Thyroid hormone signaling pathway; Phagosome; Apoptosis; Focal adhesion; Proteoglycans in cancer; Salmonella infection; Adherens junction; Regulation of actin cytoskeleton; Leukocyte transendothelial migration; Gastric acid secretion; Bacterial invasion of epithelial cells; Vibrio cholerae infection; Viral myocarditis; Influenza A; Hypertrophic cardiomyopathy (HCM); Platelet activation; Shigellosis	11

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