Protein FDR Confidence: Combined	Accession	Description	Exp. q-value: Combined	Sum PEP Score	Coverage [%]	# Peptides	# PSMs	# Unique Peptides	# AAs	MW [kDa]	calc. pI	# Peptides (by Search Engine): A2 Sequest HT (IgG 293)	# Peptides (by Search Engine): B2 Sequest HT (HKO 293)	# Peptides (by Search Engine): C2 Sequest HT (SKO 293)	# Peptides (by Search Engine): D2 Sequest HT (WT 293)	# PSMs (by Search Engine): A2 Sequest HT (IgG 293)	# PSMs (by Search Engine): B2 Sequest HT (HKO 293)	# PSMs (by Search Engine): C2 Sequest HT (SKO 293)	# PSMs (by Search Engine): D2 Sequest HT (WT 293)	Abundance: F5: Sample, IgG 293	Abundance: F6: Sample, HKO 293	Abundance: F7: Sample, SKO 293	Abundance: F8: Sample, WT 203	Abundances Count: F5: Sample, IgG 293	Abundances Count: F6: Sample, HKO 293	Abundances Count: F7: Sample, SKO 293	Abundances Count: F8: Sample, WT 203	Modifications	Biological Process	Cellular Component	Molecular Function	Pfam IDs	Entrez Gene ID	Ensembl Gene ID	Gene Symbol	Chromosome	Reactome Pathways	KEGG Pathways	# Razor Peptides
High	Q86TM6	E3 ubiquitin-protein ligase synoviolin OS=Homo sapiens OX=9606 GN=SYVN1 PE=1 SV=2	0	102.766	22	19	205	19	617	67.6	6.95		13	17	19		33	78	94	2525937.156	222807615.2	1105290197	1578334917	4	24	28	27		metabolic process;regulation of biological process;response to stimulus;transport	endoplasmic reticulum;membrane	catalytic activity;metal ion binding;protein binding	"Pf00097, Pf12678, Pf12861, Pf12906, Pf13445, Pf13639, Pf13920, Pf13923, Pf14634"	84447	ENSG00000162298.18	SYVN1	11	Hh mutants that don't undergo autocatalytic processing are degraded by ERAD; ER Quality Control Compartment (ERQC); XBP1(S) activates chaperone genes; Hedgehog ligand biogenesis	Ubiquitin mediated proteolysis; Protein processing in endoplasmic reticulum	0

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