Protein FDR Confidence: CombinedAccessionDescriptionExp. q-value: CombinedSum PEP ScoreCoverage [%]# Peptides# PSMs# Unique Peptides# AAsMW [kDa]calc. pI# Peptides (by Search Engine): A2 Sequest HT (IgG)# Peptides (by Search Engine): B2 Sequest HT (HKO)# Peptides (by Search Engine): C2 Sequest HT (SKO-1)# Peptides (by Search Engine): D2 Sequest HT (SKO-2)# Peptides (by Search Engine): E2 Sequest HT (WT-1)# Peptides (by Search Engine): F2 Sequest HT (WT-2)# PSMs (by Search Engine): A2 Sequest HT (IgG)# PSMs (by Search Engine): B2 Sequest HT (HKO)# PSMs (by Search Engine): C2 Sequest HT (SKO-1)# PSMs (by Search Engine): D2 Sequest HT (SKO-2)# PSMs (by Search Engine): E2 Sequest HT (WT-1)# PSMs (by Search Engine): F2 Sequest HT (WT-2)Abundance: F1: Sample, IgGAbundance: F2: Sample, HKOAbundance: F3: Sample, SKO-1Abundance: F4: Sample, SKO-2Abundance: F5: Sample, WT-1Abundance: F6: Sample, WT-2Abundances Count: F1: Sample, IgGAbundances Count: F2: Sample, HKOAbundances Count: F3: Sample, SKO-1Abundances Count: F4: Sample, SKO-2Abundances Count: F5: Sample, WT-1Abundances Count: F6: Sample, WT-2ModificationsBiological ProcessCellular ComponentMolecular FunctionPfam IDsEntrez Gene IDEnsembl Gene IDGene SymbolChromosomeReactome PathwaysKEGG Pathways# Razor Peptides
MediumP6233326S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=10.0241.527311138944.17.4911405658.5938404801.468811cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transportcytoplasm;cytosol;membrane;nucleus;proteasomecatalytic activity;nucleotide binding;protein binding;RNA binding"Pf00004, Pf00910, Pf01078, Pf05496, Pf07724, Pf07726, Pf07728, Pf13191, Pf13207, Pf13401"5706ENSG00000100519.11PSMC614Regulation of RAS by GAPs; CDT1 association with the CDC6:ORC:origin complex; Downstream TCR signaling; UCH proteinases; NIK-->noncanonical NF-kB signaling; Hh mutants that don't undergo autocatalytic processing are degraded by ERAD; SCF-beta-TrCP mediated degradation of Emi1; Cross-presentation of soluble exogenous antigens (endosomes); Separation of Sister Chromatids; Vpu mediated degradation of CD4; Hedgehog ligand biogenesis; Regulation of RUNX2 expression and activity; Ub-specific processing proteases; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; ER-Phagosome pathway; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; ABC-family proteins mediated transport; Regulation of activated PAK-2p34 by proteasome mediated degradation; CDK-mediated phosphorylation and removal of Cdc6; FCERI mediated NF-kB activation; Neddylation; Autodegradation of the E3 ubiquitin ligase COP1; G2/M Checkpoints; Regulation of RUNX3 expression and activity; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Regulation of expression of SLITs and ROBOs; Removal of licensing factors from origins; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of PTEN stability and activity; Regulation of DNA replication; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Antigen processing: Ubiquitination & Proteasome degradation; GLI3 is processed to GLI3R by the proteasome; SCF(Skp2)-mediated degradation of p27/p21; APC/C:Cdc20 mediated degradation of Securin; Interleukin-1 family signaling; AUF1 (hnRNP D0) binds and destabilizes mRNA; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of ornithine decarboxylase (ODC); Interleukin-20 family signaling; Hedgehog 'on' state; Ubiquitin-dependent degradation of Cyclin D1; Degradation of DVL; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Degradation of AXIN; Autodegradation of Cdh1 by Cdh1:APC/C; Asymmetric localization of PCP proteins; Orc1 removal from chromatin; M/G1 Transition; Activation of NF-kappaB in B cells; Degradation of beta-catenin by the destruction complex; MAPK6/MAPK4 signaling; Dectin-1 mediated noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosisEpstein-Barr virus infection; Proteasome0

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