Protein FDR Confidence: Combined	Accession	Description	Exp. q-value: Combined	Sum PEP Score	Coverage [%]	# Peptides	# PSMs	# Unique Peptides	# AAs	MW [kDa]	calc. pI	# Peptides (by Search Engine): A2 Sequest HT (1 IgG)	# Peptides (by Search Engine): B2 Sequest HT (3-1 sPL42)	# Peptides (by Search Engine): C2 Sequest HT (3-2 sPL42)	# Peptides (by Search Engine): D2 Sequest HT (2-1 sPL8)	# Peptides (by Search Engine): E2 Sequest HT (2-2 sPL8)	# Peptides (by Search Engine): F2 Sequest HT (4-1 sPL70)	# Peptides (by Search Engine): G2 Sequest HT (4-2 sPL70)	# PSMs (by Search Engine): A2 Sequest HT (1 IgG)	# PSMs (by Search Engine): B2 Sequest HT (3-1 sPL42)	# PSMs (by Search Engine): C2 Sequest HT (3-2 sPL42)	# PSMs (by Search Engine): D2 Sequest HT (2-1 sPL8)	# PSMs (by Search Engine): E2 Sequest HT (2-2 sPL8)	# PSMs (by Search Engine): F2 Sequest HT (4-1 sPL70)	# PSMs (by Search Engine): G2 Sequest HT (4-2 sPL70)	Abundance: F1: Sample, 1 IgG	Abundance: F4: Sample, 2-1 sPL8	Abundance: F5: Sample, 2-2 sPL8	Abundance: F2: Sample, 3-1 sPL42	Abundance: F3: Sample, 3-2 sPL42	Abundance: F6: Sample, 4-1 sPL70	Abundance: F7: Sample, 4-2 sPL70	Abundances Count: F1: Sample, 1 IgG	Abundances Count: F4: Sample, 2-1 sPL8	Abundances Count: F5: Sample, 2-2 sPL8	Abundances Count: F2: Sample, 3-1 sPL42	Abundances Count: F3: Sample, 3-2 sPL42	Abundances Count: F6: Sample, 4-1 sPL70	Abundances Count: F7: Sample, 4-2 sPL70	Modifications	Biological Process	Cellular Component	Molecular Function	Pfam IDs	Entrez Gene ID	Ensembl Gene ID	Gene Symbol	Chromosome	Reactome Pathways	KEGG Pathways	# Razor Peptides
High	Q92542	Nicastrin OS=Homo sapiens OX=9606 GN=NCSTN PE=1 SV=2	0	17.992	9	5	12	5	709	78.4	5.99		2	1			5	2		2	1			7	2		383752.9688	240629.9063	918678.75	486436.125	18915414.88	3701261.063		1	1	2	1	5	4		cell proliferation;metabolic process;regulation of biological process;response to stimulus;transport	endoplasmic reticulum;Golgi;membrane	catalytic activity;protein binding	Pf05450	23385	ENSG00000162736.15	NCSTN	1	Activated NOTCH1 Transmits Signal to the Nucleus; Signaling by NOTCH4; Regulated proteolysis of p75NTR; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NRIF signals cell death from the nucleus; Signaling by NOTCH3; EPH-ephrin mediated repulsion of cells; NOTCH2 Activation and Transmission of Signal to the Nucleus; Degradation of the extracellular matrix; Neutrophil degranulation; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Nuclear signaling by ERBB4; Signalling by NGF	Alzheimer's disease; Notch signaling pathway	0

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