Protein FDR Confidence: Combined	Accession	Description	Exp. q-value: Combined	Sum PEP Score	Coverage [%]	# Peptides	# PSMs	# Unique Peptides	# AAs	MW [kDa]	calc. pI	# Peptides (by Search Engine): A2 Sequest HT (MEF IgG)	# Peptides (by Search Engine): B2 Sequest HT (MEF Sel1L KO)	# Peptides (by Search Engine): C2 Sequest HT (MEF WT)	# Peptides (by Search Engine): D2 Sequest HT (MEF H KO)	# PSMs (by Search Engine): A2 Sequest HT (MEF IgG)	# PSMs (by Search Engine): B2 Sequest HT (MEF Sel1L KO)	# PSMs (by Search Engine): C2 Sequest HT (MEF WT)	# PSMs (by Search Engine): D2 Sequest HT (MEF H KO)	Abundance: F5: Sample, MEF IgG	Abundance: F6: Sample, MEF Sel1L KO	Abundance: F7: Sample, MEF WT	Abundance: F8: Sample, MEF H KO	Abundances Count: F5: Sample, MEF IgG	Abundances Count: F6: Sample, MEF Sel1L KO	Abundances Count: F7: Sample, MEF WT	Abundances Count: F8: Sample, MEF H KO	Modifications	Biological Process	Cellular Component	Molecular Function	Pfam IDs	Entrez Gene ID	Ensembl Gene ID	Gene Symbol	Chromosome	Reactome Pathways	KEGG Pathways	# Razor Peptides
High	P63085	Mitogen-activated protein kinase 1 OS=Mus musculus OX=10090 GN=Mapk1 PE=1 SV=3	0	33.163	36	10	21	10	358	41.2	6.98	6	4	4	6	6	5	4	6	19367789.2	11890117.75	16112633.67	25087126	6	8	7	6	Met-loss+Acetyl [N-Term]	cell communication;cell death;cell differentiation;cell proliferation;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport	cytoplasm;cytoskeleton;cytosol;endosome;Golgi;membrane;mitochondrion;nucleus	catalytic activity;nucleotide binding;protein binding;signal transducer activity	"Pf00069, Pf01636, Pf07714"	26413	ENSMUSG00000063358.15	Mapk1	16	"NCAM signaling for neurite out-growth; MAP2K and MAPK activation; Spry regulation of FGF signaling; Signal transduction by L1; FCERI mediated MAPK activation; phospho-PLA2 pathway; Regulation of HSF1-mediated heat shock response; Activated TLR4 signalling; Signaling by GPCR; Neutrophil degranulation; Gastrin-CREB signalling pathway via PKC and MAPK; MAPK1 (ERK2) activation; Recycling pathway of L1; Thrombin signalling through proteinase activated receptors (PARs); RHO GTPases Activate WASPs and WAVEs; Golgi Cisternae Pericentriolar Stack Reorganization; Interleukin-20 family signaling; RSK activation; Regulation of actin dynamics for phagocytic cup formation; Activation of the AP-1 family of transcription factors; Growth hormone receptor signaling; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Oxidative Stress Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); Oncogene Induced Senescence; ERKs are inactivated; Negative feedback regulation of MAPK pathway"	Long-term potentiation; B cell receptor signaling pathway; Influenza A; Fc epsilon RI signaling pathway; Apoptosis; Chagas disease (American trypanosomiasis); VEGF signaling pathway; Oocyte meiosis; cGMP-PKG signaling pathway; Natural killer cell mediated cytotoxicity; Adrenergic signaling in cardiomyocytes; Acute myeloid leukemia; Tuberculosis; Fc gamma R-mediated phagocytosis; cAMP signaling pathway; Colorectal cancer; Progesterone-mediated oocyte maturation; Chemokine signaling pathway; Glutamatergic synapse; Alzheimer's disease; Leishmaniasis; Phospholipase D signaling pathway; Insulin signaling pathway; Adherens junction; HIF-1 signaling pathway; Circadian entrainment; Bladder cancer; Cholinergic synapse; Prolactin signaling pathway; Hepatitis B; Neurotrophin signaling pathway; Renal cell carcinoma; Chronic myeloid leukemia; ErbB signaling pathway; Platelet activation; Proteoglycans in cancer; Thyroid cancer; Estrogen signaling pathway; MAPK signaling pathway; Focal adhesion; Osteoclast differentiation; TGF-beta signaling pathway; Prion diseases; Prostate cancer; AGE-RAGE signaling pathway in diabetic complications; Breast cancer; Toll-like receptor signaling pathway; Alcoholism; Central carbon metabolism in cancer; Retrograde endocannabinoid signaling; TNF signaling pathway; Axon guidance; Long-term depression; GnRH signaling pathway; Serotonergic synapse; FoxO signaling pathway; Toxoplasmosis; Dorso-ventral axis formation; Hepatitis C; EGFR tyrosine kinase inhibitor resistance; T cell receptor signaling pathway; Melanogenesis; Thyroid hormone signaling pathway; Vascular smooth muscle contraction; Viral carcinogenesis; Oxytocin signaling pathway; Ras signaling pathway; Endometrial cancer; Sphingolipid signaling pathway; Pathways in cancer; Glioma; Aldosterone-regulated sodium reabsorption; Platinum drug resistance; Signaling pathways regulating pluripotency of stem cells; Salmonella infection; PI3K-Akt signaling pathway; Th1 and Th2 cell differentiation; Type II diabetes mellitus; NOD-like receptor signaling pathway; Non-small cell lung cancer; Rap1 signaling pathway; Gap junction; Endocrine resistance; mTOR signaling pathway; Melanoma; Pertussis; Pancreatic cancer; Choline metabolism in cancer; Regulation of actin cytoskeleton	0

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