Protein FDR Confidence: Combined	Accession	Description	Exp. q-value: Combined	Sum PEP Score	Coverage [%]	# Peptides	# PSMs	# Unique Peptides	# AAs	MW [kDa]	calc. pI	# Peptides (by Search Engine): A2 Sequest HT (IgG N2a)	# Peptides (by Search Engine): B2 Sequest HT (SKO N2a)	# Peptides (by Search Engine): C2 Sequest HT (WT N2a)	# Peptides (by Search Engine): D2 Sequest HT (HKO N2a)	# PSMs (by Search Engine): A2 Sequest HT (IgG N2a)	# PSMs (by Search Engine): B2 Sequest HT (SKO N2a)	# PSMs (by Search Engine): C2 Sequest HT (WT N2a)	# PSMs (by Search Engine): D2 Sequest HT (HKO N2a)	Abundance: F1: Sample, IgG N2a	Abundance: F2: Sample, SKO N2a	Abundance: F3: Sample, WT N2a	Abundance: F4: Sample, HKO N2a	Abundances Count: F1: Sample, IgG N2a	Abundances Count: F2: Sample, SKO N2a	Abundances Count: F3: Sample, WT N2a	Abundances Count: F4: Sample, HKO N2a	Modifications	Biological Process	Cellular Component	Molecular Function	Pfam IDs	Entrez Gene ID	Ensembl Gene ID	Gene Symbol	Chromosome	Reactome Pathways	KEGG Pathways	# Razor Peptides
High	Q60631	Growth factor receptor-bound protein 2 OS=Mus musculus OX=10090 GN=Grb2 PE=1 SV=1	0.002	2.529	5	1	1	1	217	25.2	6.32			1				1			191253.6719	408067.4063			1	1			cell differentiation;cell organization and biogenesis;cellular component movement;defense response;metabolic process;regulation of biological process;response to stimulus;transport	cytoplasm;cytosol;endosome;Golgi;membrane;nucleus	catalytic activity;protein binding;RNA binding	"Pf00017, Pf00018, Pf07653, Pf14604"	14784	ENSMUSG00000059923.13	Grb2	11	"MET activates PI3K/AKT signaling; Signal regulatory protein family interactions; NCAM signaling for neurite out-growth; Signal attenuation; MET activates RAS signaling; FRS-mediated FGFR3 signaling; SHC-mediated cascade:FGFR3; Downstream signal transduction; FRS-mediated FGFR2 signaling; RAF/MAP kinase cascade; SHC1 events in ERBB4 signaling; GRB2 events in EGFR signaling; Spry regulation of FGF signaling; GPVI-mediated activation cascade; Regulation of KIT signaling; SHC-mediated cascade:FGFR4; FRS-mediated FGFR4 signaling; FCERI mediated MAPK activation; PI-3K cascade:FGFR4; PI-3K cascade:FGFR3; RET signaling; Signalling to RAS; EGFR downregulation; Role of LAT2/NTAL/LAB on calcium mobilization; Regulation of signaling by CBL; CD28 dependent Vav1 pathway; SOS-mediated signalling; RHO GTPases Activate WASPs and WAVEs; GRB2:SOS provides linkage to MAPK signaling for Integrins ; MET activates RAP1 and RAC1; Cargo recognition for clathrin-mediated endocytosis; SHC-related events triggered by IGF1R; Interleukin-15 signaling; MET activates PTPN11; G beta:gamma signalling through PI3Kgamma; Interleukin receptor SHC signaling; SHC1 events in EGFR signaling; Negative regulation of MET activity; Interleukin-20 family signaling; Regulation of actin dynamics for phagocytic cup formation; EGFR Transactivation by Gastrin; DAP12 signaling; Tie2 Signaling; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; GAB1 signalosome; PI3K Cascade; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; SHC-mediated cascade:FGFR2; GRB2 events in ERBB2 signaling; PI3K events in ERBB2 signaling; PI-3K cascade:FGFR2; FRS-mediated FGFR1 signaling; MET receptor recycling; FCERI mediated Ca+2 mobilization; SHC-mediated cascade:FGFR1; PI-3K cascade:FGFR1"	ErbB signaling pathway; FoxO signaling pathway; Acute myeloid leukemia; mTOR signaling pathway; T cell receptor signaling pathway; Phospholipase D signaling pathway; MAPK signaling pathway; MicroRNAs in cancer; Ras signaling pathway; Prolactin signaling pathway; Focal adhesion; Jak-STAT signaling pathway; Insulin signaling pathway; Endometrial cancer; Chemokine signaling pathway; Breast cancer; Signaling pathways regulating pluripotency of stem cells; Hepatitis B; Osteoclast differentiation; Non-small cell lung cancer; B cell receptor signaling pathway; Dorso-ventral axis formation; Proteoglycans in cancer; Neurotrophin signaling pathway; Pathways in cancer; Hepatitis C; Alcoholism; PI3K-Akt signaling pathway; Renal cell carcinoma; GnRH signaling pathway; Natural killer cell mediated cytotoxicity; Gap junction; Glioma; Fc epsilon RI signaling pathway; EGFR tyrosine kinase inhibitor resistance; Choline metabolism in cancer; Estrogen signaling pathway; Viral carcinogenesis; Chronic myeloid leukemia; Prostate cancer; Endocrine resistance	0

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