Protein FDR Confidence: Combined	Accession	Description	Exp. q-value: Combined	Sum PEP Score	Coverage [%]	# Peptides	# PSMs	# Unique Peptides	# AAs	MW [kDa]	calc. pI	Abundance Ratio: (B Stem KO) / (B Stem WT)	Abundance Ratio (log2): (B Stem KO) / (B Stem WT)	Abundance Ratio P-Value: (B Stem KO) / (B Stem WT)	Abundance Ratio Adj. P-Value: (B Stem KO) / (B Stem WT)	Abundance Ratio Variability [%]: (B Stem KO) / (B Stem WT)	Abundances (Grouped): B Stem KO	Abundances (Grouped): B Stem WT	Abundances (Grouped) CV [%]: B Stem KO	Abundances (Grouped) CV [%]: B Stem WT	Abundances (Scaled): F2: 129, Sample, B Stem KO, 1	Abundances (Scaled): F2: 130, Sample, B Stem KO, 2	Abundances (Scaled): F2: 131, Sample, B Stem KO, 3	Abundances (Scaled): F2: 126, Sample, B Stem WT, 1	Abundances (Scaled): F2: 127, Sample, B Stem WT, 2	Abundances (Scaled): F2: 128, Sample, B Stem WT, 3	Abundances (Normalized): F2: 129, Sample, B Stem KO, 1	Abundances (Normalized): F2: 130, Sample, B Stem KO, 2	Abundances (Normalized): F2: 131, Sample, B Stem KO, 3	Abundances (Normalized): F2: 126, Sample, B Stem WT, 1	Abundances (Normalized): F2: 127, Sample, B Stem WT, 2	Abundances (Normalized): F2: 128, Sample, B Stem WT, 3	Abundance: F2: 129, Sample, B Stem KO, 1	Abundance: F2: 130, Sample, B Stem KO, 2	Abundance: F2: 131, Sample, B Stem KO, 3	Abundance: F2: 126, Sample, B Stem WT, 1	Abundance: F2: 127, Sample, B Stem WT, 2	Abundance: F2: 128, Sample, B Stem WT, 3	Abundances Count: F2: 129, Sample, B Stem KO, 1	Abundances Count: F2: 130, Sample, B Stem KO, 2	Abundances Count: F2: 131, Sample, B Stem KO, 3	Abundances Count: F2: 126, Sample, B Stem WT, 1	Abundances Count: F2: 127, Sample, B Stem WT, 2	Abundances Count: F2: 128, Sample, B Stem WT, 3	Biological Process	Cellular Component	Molecular Function	Pfam IDs	Entrez Gene ID	Gene Symbol	Chromosome	Reactome Pathways	Ensembl Gene ID	KEGG Pathways	WikiPathways	# Razor Peptides	Modifications
High	O55234	Proteasome subunit beta type-5 OS=Mus musculus OX=10090 GN=Psmb5 PE=1 SV=3	0	79.201	42	10	21	10	264	28.5	7.02	1.015	0.02	0.98335791	0.999366244	6.45	99.4	100.6	4.74	10.32	96.7	103.7	94.8	113.4	97.9	93.4	1440.5	1543.6	1411.4	1688.5	1458	1391.1	1260.5	1468.6	1411.4	1492.1	1362.4	1342.9	11	11	11	11	11	11	metabolic process;response to stimulus	cytoplasm;cytosol;nucleus;proteasome	catalytic activity	Pf00227	19173	Psmb5	14	The role of GTSE1 in G2/M progression after G2 checkpoint; CDT1 association with the CDC6:ORC:origin complex; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Degradation of beta-catenin by the destruction complex; Autodegradation of the E3 ubiquitin ligase COP1; UCH proteinases; MAPK6/MAPK4 signaling; SCF-beta-TrCP mediated degradation of Emi1; CDK-mediated phosphorylation and removal of Cdc6; Separation of Sister Chromatids; SCF(Skp2)-mediated degradation of p27/p21; GLI3 is processed to GLI3R by the proteasome; Ub-specific processing proteases; Regulation of ornithine decarboxylase (ODC); Activation of NF-kappaB in B cells; FCERI mediated NF-kB activation; Degradation of GLI1 by the proteasome; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Hedgehog ligand biogenesis; Downstream TCR signaling; Autodegradation of Cdh1 by Cdh1:APC/C; Regulation of RAS by GAPs; Interleukin-1 family signaling; Asymmetric localization of PCP proteins; G2/M Checkpoints; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Regulation of PTEN stability and activity; Ubiquitin-dependent degradation of Cyclin D1; NIK-->noncanonical NF-kB signaling; Removal of licensing factors from origins; M/G1 Transition; Interleukin-20 family signaling; Regulation of RUNX2 expression and activity; Cross-presentation of soluble exogenous antigens (endosomes); ABC-family proteins mediated transport; APC/C:Cdc20 mediated degradation of Securin; Regulation of DNA replication; Dectin-1 mediated noncanonical NF-kB signaling; Antigen processing: Ubiquitination & Proteasome degradation; Orc1 removal from chromatin; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of RUNX3 expression and activity; Hedgehog 'on' state; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Degradation of DVL; Degradation of AXIN	ENSMUSG00000022193.6	Proteasome	TNF-alpha NF-kB Signaling Pathway; Proteasome Degradation	0

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