Protein FDR Confidence: CombinedAccessionDescriptionExp. q-value: CombinedSum PEP ScoreCoverage [%]# Peptides# PSMs# Unique Peptides# AAsMW [kDa]calc. pIAbundance Ratio: (Cortex KO) / (Cortex WT)Abundance Ratio (log2): (Cortex KO) / (Cortex WT)Abundance Ratio P-Value: (Cortex KO) / (Cortex WT)Abundance Ratio Adj. P-Value: (Cortex KO) / (Cortex WT)Abundance Ratio Variability [%]: (Cortex KO) / (Cortex WT)Abundances (Grouped): Cortex KOAbundances (Grouped): Cortex WTAbundances (Grouped) CV [%]: Cortex KOAbundances (Grouped) CV [%]: Cortex WTAbundances (Scaled): F1: 129, Sample, Cortex KO, 1Abundances (Scaled): F1: 130, Sample, Cortex KO, 2Abundances (Scaled): F1: 131, Sample, Cortex KO, 3Abundances (Scaled): F1: 126, Sample, Cortex WT, 1Abundances (Scaled): F1: 127, Sample, Cortex WT, 2Abundances (Scaled): F1: 128, Sample, Cortex WT, 3Abundances (Normalized): F1: 129, Sample, Cortex KO, 1Abundances (Normalized): F1: 130, Sample, Cortex KO, 2Abundances (Normalized): F1: 131, Sample, Cortex KO, 3Abundances (Normalized): F1: 126, Sample, Cortex WT, 1Abundances (Normalized): F1: 127, Sample, Cortex WT, 2Abundances (Normalized): F1: 128, Sample, Cortex WT, 3Abundance: F1: 129, Sample, Cortex KO, 1Abundance: F1: 130, Sample, Cortex KO, 2Abundance: F1: 131, Sample, Cortex KO, 3Abundance: F1: 126, Sample, Cortex WT, 1Abundance: F1: 127, Sample, Cortex WT, 2Abundance: F1: 128, Sample, Cortex WT, 3Abundances Count: F1: 129, Sample, Cortex KO, 1Abundances Count: F1: 130, Sample, Cortex KO, 2Abundances Count: F1: 131, Sample, Cortex KO, 3Abundances Count: F1: 126, Sample, Cortex WT, 1Abundances Count: F1: 127, Sample, Cortex WT, 2Abundances Count: F1: 128, Sample, Cortex WT, 3Biological ProcessCellular ComponentMolecular FunctionPfam IDsEntrez Gene IDGene SymbolChromosomeReactome PathwaysEnsembl Gene IDKEGG PathwaysWikiPathways# Razor PeptidesModifications
HighQ60631Growth factor receptor-bound protein 2 OS=Mus musculus OX=10090 GN=Grb2 PE=1 SV=1068.5435911241121725.26.321.0320.050.586884610.9747563981.141029816.4813.47115.2104.782.7111.7100.785.11912.71737.613721853.21670.61412.11793.61568.3137016591453.81412.1111111111111cell differentiation;cell organization and biogenesis;cellular component movement;defense response;metabolic process;regulation of biological process;response to stimulus;transportcytoplasm;cytosol;endosome;Golgi;membrane;nucleuscatalytic activity;protein binding;RNA binding"Pf00017, Pf00018, Pf07653, Pf14604"14784Grb211"MET activates PI3K/AKT signaling; Signal regulatory protein family interactions; NCAM signaling for neurite out-growth; Signal attenuation; MET activates RAS signaling; FRS-mediated FGFR3 signaling; SHC-mediated cascade:FGFR3; Downstream signal transduction; FRS-mediated FGFR2 signaling; RAF/MAP kinase cascade; SHC1 events in ERBB4 signaling; GRB2 events in EGFR signaling; Spry regulation of FGF signaling; GPVI-mediated activation cascade; Regulation of KIT signaling; SHC-mediated cascade:FGFR4; FRS-mediated FGFR4 signaling; FCERI mediated MAPK activation; PI-3K cascade:FGFR4; PI-3K cascade:FGFR3; RET signaling; Signalling to RAS; EGFR downregulation; Role of LAT2/NTAL/LAB on calcium mobilization; Regulation of signaling by CBL; CD28 dependent Vav1 pathway; SOS-mediated signalling; RHO GTPases Activate WASPs and WAVEs; GRB2:SOS provides linkage to MAPK signaling for Integrins ; MET activates RAP1 and RAC1; Cargo recognition for clathrin-mediated endocytosis; SHC-related events triggered by IGF1R; Interleukin-15 signaling; MET activates PTPN11; G beta:gamma signalling through PI3Kgamma; Interleukin receptor SHC signaling; SHC1 events in EGFR signaling; Negative regulation of MET activity; Interleukin-20 family signaling; Regulation of actin dynamics for phagocytic cup formation; EGFR Transactivation by Gastrin; DAP12 signaling; Tie2 Signaling; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; GAB1 signalosome; PI3K Cascade; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; SHC-mediated cascade:FGFR2; GRB2 events in ERBB2 signaling; PI3K events in ERBB2 signaling; PI-3K cascade:FGFR2; FRS-mediated FGFR1 signaling; MET receptor recycling; FCERI mediated Ca+2 mobilization; SHC-mediated cascade:FGFR1; PI-3K cascade:FGFR1"ENSMUSG00000059923.13ErbB signaling pathway; FoxO signaling pathway; Acute myeloid leukemia; mTOR signaling pathway; T cell receptor signaling pathway; Phospholipase D signaling pathway; MAPK signaling pathway; MicroRNAs in cancer; Ras signaling pathway; Prolactin signaling pathway; Focal adhesion; Jak-STAT signaling pathway; Insulin signaling pathway; Endometrial cancer; Chemokine signaling pathway; Breast cancer; Signaling pathways regulating pluripotency of stem cells; Hepatitis B; Osteoclast differentiation; Non-small cell lung cancer; B cell receptor signaling pathway; Dorso-ventral axis formation; Proteoglycans in cancer; Neurotrophin signaling pathway; Pathways in cancer; Hepatitis C; Alcoholism; PI3K-Akt signaling pathway; Renal cell carcinoma; GnRH signaling pathway; Natural killer cell mediated cytotoxicity; Gap junction; Glioma; Fc epsilon RI signaling pathway; EGFR tyrosine kinase inhibitor resistance; Choline metabolism in cancer; Estrogen signaling pathway; Viral carcinogenesis; Chronic myeloid leukemia; Prostate cancer; Endocrine resistanceIL-9 Signaling Pathway; Estrogen signaling; EPO Receptor Signaling; ErbB signaling pathway; IL-5 Signaling Pathway; PluriNetWork; Signaling of Hepatocyte Growth Factor Receptor; Chemokine signaling pathway; Focal Adhesion-PI3K-Akt-mTOR-signaling pathway; IL-7 Signaling Pathway; ESC Pluripotency Pathways; p38 MAPK Signaling Pathway; IL-3 Signaling Pathway; IL-6 signaling Pathway; Kit Receptor Signaling Pathway; IL-2 Signaling Pathway; Alpha6-Beta4 Integrin Signaling Pathway; MAPK signaling pathway; EGFR1 Signaling Pathway; Integrin-mediated Cell Adhesion; Insulin Signaling; Focal Adhesion0

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