Protein FDR Confidence: CombinedAccessionDescriptionExp. q-value: CombinedSum PEP ScoreCoverage [%]# Peptides# PSMs# Unique Peptides# AAsMW [kDa]calc. pI# Peptides (by Search Engine): A2 Sequest HT (IgG Adipo)# Peptides (by Search Engine): B2 Sequest HT (SelL -/- Adipo)# Peptides (by Search Engine): C2 Sequest HT# Peptides (by Search Engine): D2 Sequest HT (Hrd1 -/- Adipo)# PSMs (by Search Engine): A2 Sequest HT (IgG Adipo)# PSMs (by Search Engine): B2 Sequest HT (SelL -/- Adipo)# PSMs (by Search Engine): C2 Sequest HT# PSMs (by Search Engine): D2 Sequest HT (Hrd1 -/- Adipo)Abundance: F1: Sample, IgG AdipoAbundance: F2: Sample, SelL -/- AdipoAbundance: F3: Sample, WT AdipoAbundance: F4: Sample, Hrd1 -/- AdipoAbundances Count: F1: Sample, IgG AdipoAbundances Count: F2: Sample, SelL -/- AdipoAbundances Count: F3: Sample, WT AdipoAbundances Count: F4: Sample, Hrd1 -/- AdipoModificationsBiological ProcessCellular ComponentMolecular FunctionPfam IDsEntrez Gene IDEnsembl Gene IDGene SymbolChromosomeReactome PathwaysKEGG Pathways# Razor Peptides
HighP62983Ubiquitin-40S ribosomal protein S27a OS=Mus musculus OX=10090 GN=Rps27a PE=1 SV=2020.14140515515617.99.64144117523313330.56316059458.1314805962.2512663703.254544metabolic processcytoplasm;cytosol;membrane;nucleus;ribosomemetal ion binding;protein binding;RNA binding;structural molecule activity"Pf00240, Pf01599, Pf11976, Pf13019, Pf13881, Pf14560"78294; 619900; 100042019ENSMUSG00000020460.15Rps27a; Rps27a-ps2; LOC10004201911; 9"Termination of translesion DNA synthesis; PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1; NOD1/2 Signaling Pathway; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Ovarian tumor domain proteases; UCH proteinases; Stimuli-sensing channels; p75NTR recruits signalling complexes; Josephin domain DUBs; Spry regulation of FGF signaling; SRP-dependent cotranslational protein targeting to membrane; Ub-specific processing proteases; IKK complex recruitment mediated by RIP1; IRAK2 mediated activation of TAK1 complex; Activation of NF-kappaB in B cells; EGFR downregulation; Regulation of necroptotic cell death; Regulation of signaling by CBL; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Formation of a pool of free 40S subunits; Regulation of TP53 Degradation; Regulation of TP53 Activity through Phosphorylation; NF-kB is activated and signals survival; Downstream TCR signaling; Association of licensing factors with the pre-replicative complex; Autodegradation of Cdh1 by Cdh1:APC/C; TRAF6-mediated induction of TAK1 complex within TLR4 complex; Asymmetric localization of PCP proteins; Interleukin-1 family signaling; TNFR1-induced NFkappaB signaling pathway; G2/M Checkpoints; Regulation of PTEN localization; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Mus musculus biological processes; Regulation of PTEN stability and activity; APC-Cdc20 mediated degradation of Nek2A; Formation of the ternary complex, and subsequently, the 43S complex; Regulation of TP53 Activity through Methylation; E3 ubiquitin ligases ubiquitinate target proteins; Translesion synthesis by POLI; Interleukin-20 family signaling; Downregulation of ERBB4 signaling; Dual Incision in GG-NER; ER Quality Control Compartment (ERQC); Neddylation; Negative regulators of DDX58/IFIH1 signaling; Gap-filling DNA repair synthesis and ligation in TC-NER; APC/C:Cdc20 mediated degradation of Securin; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Antigen processing: Ubiquitination & Proteasome degradation; Translesion Synthesis by POLH; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; TAK1 activates NFkB by phosphorylation and activation of IKKs complex; Oxidative Stress Induced Senescence; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Regulation of PLK1 Activity at G2/M Transition; Senescence-Associated Secretory Phenotype (SASP); Oncogene Induced Senescence; Formation of TC-NER Pre-Incision Complex; AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of expression of SLITs and ROBOs; APC/C:Cdc20 mediated degradation of Cyclin B; Translation initiation complex formation; Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon; Regulation of FZD by ubiquitination; Recognition of DNA damage by PCNA-containing replication complex; Translesion synthesis by REV1; Circadian Clock; Degradation of DVL; Degradation of AXIN; The role of GTSE1 in G2/M progression after G2 checkpoint; CDT1 association with the CDC6:ORC:origin complex; Endosomal Sorting Complex Required For Transport (ESCRT); Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Degradation of beta-catenin by the destruction complex; NRIF signals cell death from the nucleus; Autodegradation of the E3 ubiquitin ligase COP1; MAPK6/MAPK4 signaling; SCF-beta-TrCP mediated degradation of Emi1; CDK-mediated phosphorylation and removal of Cdc6; Separation of Sister Chromatids; SCF(Skp2)-mediated degradation of p27/p21; Regulation of innate immune responses to cytosolic DNA; GLI3 is processed to GLI3R by the proteasome; Translesion synthesis by POLK; Activated TLR4 signalling; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); DNA Damage Recognition in GG-NER; Degradation of GLI1 by the proteasome; FCERI mediated NF-kB activation; Formation of Incision Complex in GG-NER; Gap-filling DNA repair synthesis and ligation in GG-NER; Hedgehog ligand biogenesis; Regulation of RAS by GAPs; Activated NOTCH1 Transmits Signal to the Nucleus; Cyclin D associated events in G1; Dual incision in TC-NER; Negative regulation of MAPK pathway; Pink/Parkin Mediated Mitophagy; Cargo recognition for clathrin-mediated endocytosis; Ubiquitin-dependent degradation of Cyclin D1; Metalloprotease DUBs; MAP3K8 (TPL2)-dependent MAPK1/3 activation; NIK-->noncanonical NF-kB signaling; Removal of licensing factors from origins; IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation; M/G1 Transition; Negative regulation of MET activity; L13a-mediated translational silencing of Ceruloplasmin expression; Downregulation of ERBB2:ERBB3 signaling; activated TAK1 mediates p38 MAPK activation; Regulation of RUNX2 expression and activity; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ABC-family proteins mediated transport; Regulation of DNA replication; Glycogen synthesis; Dectin-1 mediated noncanonical NF-kB signaling; Downregulation of SMAD2/3:SMAD4 transcriptional activity; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Orc1 removal from chromatin; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition); Regulation of TNFR1 signaling; Regulation of RUNX3 expression and activity; Hedgehog 'on' state; Fanconi Anemia Pathway; HDR through Homologous Recombination (HRR); Iron uptake and transport; JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Signalling by NGF; Downregulation of TGF-beta receptor signaling"Ribosome0

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