Protein FDR Confidence: Combined	Accession	Description	Exp. q-value: Combined	Sum PEP Score	Coverage [%]	# Peptides	# PSMs	# Unique Peptides	# AAs	MW [kDa]	calc. pI	# Peptides (by Search Engine): A2 Sequest HT (IgG Adipo)	# Peptides (by Search Engine): B2 Sequest HT (SelL -/- Adipo)	# Peptides (by Search Engine): C2 Sequest HT	# Peptides (by Search Engine): D2 Sequest HT (Hrd1 -/- Adipo)	# PSMs (by Search Engine): A2 Sequest HT (IgG Adipo)	# PSMs (by Search Engine): B2 Sequest HT (SelL -/- Adipo)	# PSMs (by Search Engine): C2 Sequest HT	# PSMs (by Search Engine): D2 Sequest HT (Hrd1 -/- Adipo)	Abundance: F1: Sample, IgG Adipo	Abundance: F2: Sample, SelL -/- Adipo	Abundance: F3: Sample, WT Adipo	Abundance: F4: Sample, Hrd1 -/- Adipo	Abundances Count: F1: Sample, IgG Adipo	Abundances Count: F2: Sample, SelL -/- Adipo	Abundances Count: F3: Sample, WT Adipo	Abundances Count: F4: Sample, Hrd1 -/- Adipo	Modifications	Biological Process	Cellular Component	Molecular Function	Pfam IDs	Entrez Gene ID	Ensembl Gene ID	Gene Symbol	Chromosome	Reactome Pathways	KEGG Pathways	# Razor Peptides
High	Q9CWH6	Proteasome subunit alpha type-8 OS=Mus musculus OX=10090 GN=Psma8 PE=1 SV=1	0	2.869	4	1	3	1	250	27.8	8.69		1	1	1		1	1	1	1862199.375	6490181	7343773.563	21595420	1	1	1	1		metabolic process	cytoplasm;cytosol;nucleus;proteasome	catalytic activity	"Pf00227, Pf10584"	73677	ENSMUSG00000036743.3	Psma8	18	The role of GTSE1 in G2/M progression after G2 checkpoint; CDT1 association with the CDC6:ORC:origin complex; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Degradation of beta-catenin by the destruction complex; Autodegradation of the E3 ubiquitin ligase COP1; UCH proteinases; MAPK6/MAPK4 signaling; SCF-beta-TrCP mediated degradation of Emi1; CDK-mediated phosphorylation and removal of Cdc6; Separation of Sister Chromatids; GLI3 is processed to GLI3R by the proteasome; Ub-specific processing proteases; Regulation of ornithine decarboxylase (ODC); Activation of NF-kappaB in B cells; FCERI mediated NF-kB activation; Degradation of GLI1 by the proteasome; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Hedgehog ligand biogenesis; Downstream TCR signaling; Regulation of RAS by GAPs; Interleukin-1 family signaling; Asymmetric localization of PCP proteins; G2/M Checkpoints; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Regulation of PTEN stability and activity; Ubiquitin-dependent degradation of Cyclin D1; NIK-->noncanonical NF-kB signaling; Removal of licensing factors from origins; M/G1 Transition; Interleukin-20 family signaling; Cross-presentation of soluble exogenous antigens (endosomes); ABC-family proteins mediated transport; APC/C:Cdc20 mediated degradation of Securin; Regulation of DNA replication; Dectin-1 mediated noncanonical NF-kB signaling; Antigen processing: Ubiquitination & Proteasome degradation; Orc1 removal from chromatin; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; AUF1 (hnRNP D0) binds and destabilizes mRNA; Hedgehog 'on' state; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Degradation of DVL; Degradation of AXIN	Proteasome	0

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