Protein FDR Confidence: CombinedAccessionDescriptionExp. q-value: CombinedSum PEP ScoreCoverage [%]# Peptides# PSMs# Unique Peptides# AAsMW [kDa]calc. pI# Peptides (by Search Engine): A2 Sequest HT (5W kidney IgG)# Peptides (by Search Engine): B2 Sequest HT (5W kidney SKO)# Peptides (by Search Engine): C2 Sequest HT (5W kidney WT)# PSMs (by Search Engine): A2 Sequest HT (5W kidney IgG)# PSMs (by Search Engine): B2 Sequest HT (5W kidney SKO)# PSMs (by Search Engine): C2 Sequest HT (5W kidney WT)Abundance: F1: Sample, 5W kidney IgGAbundance: F2: Sample, 5W Kidney SKOAbundance: F3: Sample, 5W kidney WTAbundances Count: F1: Sample, 5W kidney IgGAbundances Count: F2: Sample, 5W Kidney SKOAbundances Count: F3: Sample, 5W kidney WTModificationsBiological ProcessCellular ComponentMolecular FunctionPfam IDsEntrez Gene IDEnsembl Gene IDGene SymbolChromosomeReactome PathwaysKEGG Pathways# Razor Peptides
HighQ8BVQ926S proteasome regulatory subunit 7 OS=Mus musculus OX=10090 GN=Psmc2 PE=1 SV=10.0023.882423247552.86.281212106269.2031764009.43751441567.188122cell differentiation;metabolic process;regulation of biological processcytoplasm;cytosol;membrane;nucleus;proteasomecatalytic activity;nucleotide binding;protein binding"Pf00004, Pf00158, Pf07724, Pf07726, Pf07728, Pf13191, Pf13401"19181ENSMUSG00000028932.7Psmc25The role of GTSE1 in G2/M progression after G2 checkpoint; CDT1 association with the CDC6:ORC:origin complex; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Degradation of beta-catenin by the destruction complex; Autodegradation of the E3 ubiquitin ligase COP1; UCH proteinases; MAPK6/MAPK4 signaling; SCF-beta-TrCP mediated degradation of Emi1; CDK-mediated phosphorylation and removal of Cdc6; Separation of Sister Chromatids; SCF(Skp2)-mediated degradation of p27/p21; GLI3 is processed to GLI3R by the proteasome; Ub-specific processing proteases; Regulation of ornithine decarboxylase (ODC); Activation of NF-kappaB in B cells; Degradation of GLI1 by the proteasome; FCERI mediated NF-kB activation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Hedgehog ligand biogenesis; Neutrophil degranulation; Downstream TCR signaling; Autodegradation of Cdh1 by Cdh1:APC/C; Regulation of RAS by GAPs; Interleukin-1 family signaling; Asymmetric localization of PCP proteins; G2/M Checkpoints; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Regulation of PTEN stability and activity; Ubiquitin-dependent degradation of Cyclin D1; NIK-->noncanonical NF-kB signaling; Removal of licensing factors from origins; M/G1 Transition; Interleukin-20 family signaling; Regulation of RUNX2 expression and activity; Cross-presentation of soluble exogenous antigens (endosomes); ABC-family proteins mediated transport; APC/C:Cdc20 mediated degradation of Securin; Regulation of DNA replication; Dectin-1 mediated noncanonical NF-kB signaling; Antigen processing: Ubiquitination & Proteasome degradation; Orc1 removal from chromatin; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of RUNX3 expression and activity; Hedgehog 'on' state; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Degradation of DVL; Degradation of AXINProteasome; Epstein-Barr virus infection0

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