| Protein FDR Confidence: Combined | Accession | Description | Exp. q-value: Combined | Sum PEP Score | Coverage [%] | # Peptides | # PSMs | # Unique Peptides | # AAs | MW [kDa] | calc. pI | # Peptides (by Search Engine): E2 Sequest HT (Liver IgG) | # Peptides (by Search Engine): F2 Sequest HT (Liver SKO) | # Peptides (by Search Engine): G2 Sequest HT (Liver WT) | # Peptides (by Search Engine): H2 Sequest HT (Liver HKO) | # PSMs (by Search Engine): E2 Sequest HT (Liver IgG) | # PSMs (by Search Engine): F2 Sequest HT (Liver SKO) | # PSMs (by Search Engine): G2 Sequest HT (Liver WT) | # PSMs (by Search Engine): H2 Sequest HT (Liver HKO) | Abundance: F5: Sample, Liver IgG | Abundance: F6: Sample, Liver SKO | Abundance: F7: Sample, Liver WT | Abundance: F8: Sample, Liver HKO | Abundances Count: F5: Sample, Liver IgG | Abundances Count: F6: Sample, Liver SKO | Abundances Count: F7: Sample, Liver WT | Abundances Count: F8: Sample, Liver HKO | Modifications | Biological Process | Cellular Component | Molecular Function | Pfam IDs | Entrez Gene ID | Ensembl Gene ID | Gene Symbol | Chromosome | Reactome Pathways | KEGG Pathways | # Razor Peptides |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Medium | P81122 | Insulin receptor substrate 2 OS=Mus musculus OX=10090 GN=Irs2 PE=1 SV=2 | 0.01 | 2.223 | 1 | 1 | 2 | 1 | 1321 | 136.7 | 8.69 | 98315.05469 | 13869.86328 | 10629.20605 | 1 | 1 | 1 | cell proliferation;cellular homeostasis;regulation of biological process;response to stimulus | cytoplasm;cytosol;membrane | protein binding;signal transducer activity | "Pf00169, Pf02174, Pf15413" | 384783 | ENSMUSG00000038894.7 | Irs2 | 8 | "RET signaling; PI3K Cascade; Signal attenuation; Interleukin-7 signaling; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Interleukin-20 family signaling; Signaling by Leptin; IRS activation; Signaling by Leptin; RAF/MAP kinase cascade; SOS-mediated signalling; Mus musculus biological processes; PI3K/AKT activation" | FoxO signaling pathway; Type II diabetes mellitus; MicroRNAs in cancer; Regulation of lipolysis in adipocytes; Insulin signaling pathway; Insulin resistance; Longevity regulating pathway; Non-alcoholic fatty liver disease (NAFLD); cGMP-PKG signaling pathway; Adipocytokine signaling pathway; AMPK signaling pathway; Longevity regulating pathway - multiple species | 0 |