Protein FDR Confidence: Combined	Accession	Description	Exp. q-value: Combined	Sum PEP Score	Coverage [%]	# Peptides	# PSMs	# Unique Peptides	# AAs	MW [kDa]	calc. pI	# Peptides (by Search Engine): E2 Sequest HT (Liver IgG)	# Peptides (by Search Engine): F2 Sequest HT (Liver SKO)	# Peptides (by Search Engine): G2 Sequest HT (Liver WT)	# Peptides (by Search Engine): H2 Sequest HT (Liver HKO)	# PSMs (by Search Engine): E2 Sequest HT (Liver IgG)	# PSMs (by Search Engine): F2 Sequest HT (Liver SKO)	# PSMs (by Search Engine): G2 Sequest HT (Liver WT)	# PSMs (by Search Engine): H2 Sequest HT (Liver HKO)	Abundance: F5: Sample, Liver IgG	Abundance: F6: Sample, Liver SKO	Abundance: F7: Sample, Liver WT	Abundance: F8: Sample, Liver HKO	Abundances Count: F5: Sample, Liver IgG	Abundances Count: F6: Sample, Liver SKO	Abundances Count: F7: Sample, Liver WT	Abundances Count: F8: Sample, Liver HKO	Modifications	Biological Process	Cellular Component	Molecular Function	Pfam IDs	Entrez Gene ID	Ensembl Gene ID	Gene Symbol	Chromosome	Reactome Pathways	KEGG Pathways	# Razor Peptides
High	Q01279	Epidermal growth factor receptor OS=Mus musculus OX=10090 GN=Egfr PE=1 SV=1	0	22.141	7	7	12	7	1210	134.8	6.86	5	1	1	3	6	1	1	4	2768665.313	141065.707	518410.2188	1079457.414	4	2	3	5		cell organization and biogenesis;cell proliferation;cellular component movement;development;metabolic process;regulation of biological process;response to stimulus;transport	cell surface;cytoplasm;endoplasmic reticulum;endosome;Golgi;membrane;nucleus;organelle lumen	catalytic activity;enzyme regulator activity;nucleotide binding;protein binding;receptor activity;signal transducer activity	"Pf00069, Pf00757, Pf01030, Pf07714, Pf14843"	13649	ENSMUSG00000020122.16	Egfr	11	"EGFR interacts with phospholipase C-gamma; Downregulation of ERBB2 signaling; GAB1 signalosome; Signaling by GPCR; EGFR downregulation; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; ERBB2 Regulates Cell Motility; SHC1 events in EGFR signaling; Interleukin-20 family signaling; Signaling by ERBB4; EGFR Transactivation by Gastrin; PI3K events in ERBB2 signaling; RAF/MAP kinase cascade; PTK6 promotes HIF1A stabilization; GRB2 events in EGFR signaling; ERBB2 Activates PTK6 Signaling; Signal transduction by L1; Cargo recognition for clathrin-mediated endocytosis; SHC1 events in ERBB2 signaling"	Oxytocin signaling pathway; ErbB signaling pathway; FoxO signaling pathway; Endocytosis; Phospholipase D signaling pathway; Regulation of actin cytoskeleton; MAPK signaling pathway; MicroRNAs in cancer; Ras signaling pathway; Focal adhesion; Endometrial cancer; Breast cancer; Melanoma; Non-small cell lung cancer; Adherens junction; Dorso-ventral axis formation; Proteoglycans in cancer; Rap1 signaling pathway; HIF-1 signaling pathway; Pathways in cancer; Calcium signaling pathway; Hepatitis C; Pancreatic cancer; PI3K-Akt signaling pathway; GnRH signaling pathway; Gap junction; Glioma; EGFR tyrosine kinase inhibitor resistance; Central carbon metabolism in cancer; Choline metabolism in cancer; Estrogen signaling pathway; Cytokine-cytokine receptor interaction; Prostate cancer; Endocrine resistance; Bladder cancer	0

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