Protein FDR Confidence: CombinedAccessionDescriptionExp. q-value: CombinedSum PEP ScoreCoverage [%]# Peptides# PSMs# Unique Peptides# AAsMW [kDa]calc. pI# Peptides (by Search Engine): A2 Sequest HT (Ig)# Peptides (by Search Engine): B2 Sequest HT (SKO)# Peptides (by Search Engine): C2 Sequest HT (WT)# Peptides (by Search Engine): D2 Sequest HT (HKO)# PSMs (by Search Engine): A2 Sequest HT (Ig)# PSMs (by Search Engine): B2 Sequest HT (SKO)# PSMs (by Search Engine): C2 Sequest HT (WT)# PSMs (by Search Engine): D2 Sequest HT (HKO)Abundance: F1: Sample, IgGAbundance: F2: Sample, SKOAbundance: F3: Sample, WTAbundance: F4: Sample, HKOAbundances Count: F1: Sample, IgGAbundances Count: F2: Sample, SKOAbundances Count: F3: Sample, WTAbundances Count: F4: Sample, HKOModificationsBiological ProcessCellular ComponentMolecular FunctionPfam IDsEntrez Gene IDEnsembl Gene IDGene SymbolChromosomeReactome PathwaysKEGG Pathways# Razor Peptides
HighO43318Mitogen-activated protein kinase kinase kinase 7 OS=Homo sapiens OX=9606 GN=MAP3K7 PE=1 SV=1010.397622260667.27.112212013541cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimuluscytoplasm;cytosol;membrane;nucleuscatalytic activity;metal ion binding;nucleotide binding;protein binding;signal transducer activity"Pf00069, Pf01636, Pf03962, Pf07714"6885ENSG00000135341.17MAP3K76"Downstream TCR signaling; NOD1/2 Signaling Pathway; TRAF6-mediated induction of TAK1 complex within TLR4 complex; TAK1 activates NFkB by phosphorylation and activation of IKKs complex; TNFR1-induced NFkappaB signaling pathway; Activated TLR4 signalling; Interleukin-1 family signaling; activated TAK1 mediates p38 MAPK activation; TICAM1,TRAF6-dependent induction of TAK1 complex; IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation; Ub-specific processing proteases; Ca2+ pathway; IRAK2 mediated activation of TAK1 complex; FCERI mediated NF-kB activation; Activation of NF-kappaB in B cells; JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1; CLEC7A (Dectin-1) signaling"T cell receptor signaling pathway; TNF signaling pathway; NOD-like receptor signaling pathway; Osteoclast differentiation; Epstein-Barr virus infection; Leishmaniasis; MAPK signaling pathway; NF-kappa B signaling pathway; Toxoplasmosis; Wnt signaling pathway; AMPK signaling pathway; Adherens junction; Measles; Toll-like receptor signaling pathway; Herpes simplex infection; RIG-I-like receptor signaling pathway0

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