Protein FDR Confidence: Combined	Accession	Description	Exp. q-value: Combined	Sum PEP Score	Coverage [%]	# Peptides	# PSMs	# Unique Peptides	# AAs	MW [kDa]	calc. pI	# Peptides (by Search Engine): A2 Sequest HT (Ig)	# Peptides (by Search Engine): B2 Sequest HT (SKO)	# Peptides (by Search Engine): C2 Sequest HT (WT)	# Peptides (by Search Engine): D2 Sequest HT (HKO)	# PSMs (by Search Engine): A2 Sequest HT (Ig)	# PSMs (by Search Engine): B2 Sequest HT (SKO)	# PSMs (by Search Engine): C2 Sequest HT (WT)	# PSMs (by Search Engine): D2 Sequest HT (HKO)	Abundance: F1: Sample, IgG	Abundance: F2: Sample, SKO	Abundance: F3: Sample, WT	Abundance: F4: Sample, HKO	Abundances Count: F1: Sample, IgG	Abundances Count: F2: Sample, SKO	Abundances Count: F3: Sample, WT	Abundances Count: F4: Sample, HKO	Modifications	Biological Process	Cellular Component	Molecular Function	Pfam IDs	Entrez Gene ID	Ensembl Gene ID	Gene Symbol	Chromosome	Reactome Pathways	KEGG Pathways	# Razor Peptides
High	P28482	Mitogen-activated protein kinase 1 OS=Homo sapiens OX=9606 GN=MAPK1 PE=1 SV=3	0	41.982	28	9	14	7	360	41.4	6.98	9			1	13			1	37365853.63	1737552.211	1513309.703	3341352.125	9	5	4	3	Met-loss+Acetyl [N-Term]	cell communication;cell death;cell differentiation;cell proliferation;cellular component movement;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport	cytoplasm;cytoskeleton;cytosol;endosome;extracellular;Golgi;membrane;mitochondrion;nucleus;organelle lumen	catalytic activity;DNA binding;nucleotide binding;protein binding;signal transducer activity	"Pf00069, Pf01636, Pf07714"	5594	ENSG00000100030.14	MAPK1	22	"phospho-PLA2 pathway; NCAM signaling for neurite out-growth; Activated TLR4 signalling; Negative feedback regulation of MAPK pathway; RUNX2 regulates osteoblast differentiation; Neutrophil degranulation; Regulation of actin dynamics for phagocytic cup formation; Signaling by BRAF and RAF fusions; Signaling by RAS mutants; Signaling by high-kinase activity BRAF mutants; Signaling by moderate kinase activity BRAF mutants; RSK activation; ERKs are inactivated; MAP2K and MAPK activation; FCERI mediated MAPK activation; Signaling by GPCR; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signal attenuation; Activation of the AP-1 family of transcription factors; Golgi Cisternae Pericentriolar Stack Reorganization; MAPK1 (ERK2) activation; Interleukin-20 family signaling; Spry regulation of FGF signaling; Signal transduction by L1; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Regulation of HSF1-mediated heat shock response; Advanced glycosylation endproduct receptor signaling; Recycling pathway of L1; Thrombin signalling through proteinase activated receptors (PARs); Gastrin-CREB signalling pathway via PKC and MAPK; Regulation of PTEN gene transcription; RHO GTPases Activate WASPs and WAVEs; Oncogene Induced Senescence; Growth hormone receptor signaling; Senescence-Associated Secretory Phenotype (SASP); Oxidative Stress Induced Senescence"	Viral carcinogenesis; Chagas disease (American trypanosomiasis); Serotonergic synapse; Th1 and Th2 cell differentiation; TGF-beta signaling pathway; T cell receptor signaling pathway; Dorso-ventral axis formation; TNF signaling pathway; NOD-like receptor signaling pathway; Osteoclast differentiation; Prion diseases; Vascular smooth muscle contraction; Glutamatergic synapse; Hepatitis B; Insulin signaling pathway; HIF-1 signaling pathway; Central carbon metabolism in cancer; Pancreatic cancer; FoxO signaling pathway; Prolactin signaling pathway; MicroRNAs in cancer; Phospholipase D signaling pathway; cGMP-PKG signaling pathway; Chronic myeloid leukemia; Neurotrophin signaling pathway; B cell receptor signaling pathway; VEGF signaling pathway; Leishmaniasis; Acute myeloid leukemia; Rap1 signaling pathway; Non-small cell lung cancer; Progesterone-mediated oocyte maturation; MAPK signaling pathway; Oxytocin signaling pathway; Circadian entrainment; Endometrial cancer; Breast cancer; Colorectal cancer; Type II diabetes mellitus; Natural killer cell mediated cytotoxicity; ErbB signaling pathway; Pathways in cancer; Prostate cancer; Long-term potentiation; Thyroid hormone signaling pathway; Glioma; Gap junction; Adrenergic signaling in cardiomyocytes; AGE-RAGE signaling pathway in diabetic complications; Renal cell carcinoma; Tuberculosis; Pertussis; Melanoma; EGFR tyrosine kinase inhibitor resistance; Toxoplasmosis; Apoptosis; Melanogenesis; Focal adhesion; Proteoglycans in cancer; Choline metabolism in cancer; Alzheimer's disease; mTOR signaling pathway; Aldosterone-regulated sodium reabsorption; Salmonella infection; Adherens junction; Long-term depression; Regulation of actin cytoskeleton; Retrograde endocannabinoid signaling; Oocyte meiosis; Sphingolipid signaling pathway; Toll-like receptor signaling pathway; Bladder cancer; Fc epsilon RI signaling pathway; Thyroid cancer; Hepatitis C; Alcoholism; Ras signaling pathway; Fc gamma R-mediated phagocytosis; Endocrine resistance; GnRH signaling pathway; Chemokine signaling pathway; Axon guidance; Signaling pathways regulating pluripotency of stem cells; cAMP signaling pathway; Influenza A; Estrogen signaling pathway; Cholinergic synapse; PI3K-Akt signaling pathway; Platelet activation; Shigellosis; Platinum drug resistance	2

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