Protein FDR Confidence: Combined Accession Description Exp. q-value: Combined Sum PEP Score Coverage [%] # Peptides # PSMs # Unique Peptides # AAs MW [kDa] calc. pI # Peptides (by Search Engine): I2 Sequest HT (BAT IgG) # Peptides (by Search Engine): J2 Sequest HT (BAT SKO) # Peptides (by Search Engine): K2 Sequest HT (BAT WT) # Peptides (by Search Engine): L2 Sequest HT (BAT HKO) # PSMs (by Search Engine): I2 Sequest HT (BAT IgG) # PSMs (by Search Engine): J2 Sequest HT (BAT SKO) # PSMs (by Search Engine): K2 Sequest HT (BAT WT) # PSMs (by Search Engine): L2 Sequest HT (BAT HKO) "Abundance: F9: Sample, BAT IgG" "Abundance: F10: Sample, BAT SKO" "Abundance: F11: Sample, BAT WT" "Abundance: F12: Sample, Liver HKO" "Abundances Count: F9: Sample, BAT IgG" "Abundances Count: F10: Sample, BAT SKO" "Abundances Count: F11: Sample, BAT WT" "Abundances Count: F12: Sample, Liver HKO" Modifications Biological Process Cellular Component Molecular Function Pfam IDs Entrez Gene ID Ensembl Gene ID Gene Symbol Chromosome Reactome Pathways KEGG Pathways # Razor Peptides High P68369 Tubulin alpha-1A chain OS=Mus musculus OX=10090 GN=Tuba1a PE=1 SV=1 0 139.774 57 23 276 7 451 50.1 5.06 1 2 1 1 2 1 1327997.399 1559981.596 591923.1733 6609193.15 13 15 7 14 cell organization and biogenesis cytoplasm;cytoskeleton;endosome;membrane;nucleus catalytic activity;nucleotide binding;protein binding;structural molecule activity "Pf00091, Pf03953" 22142 ENSMUSG00000072235.5 Tuba1a 15 Anchoring of the basal body to the plasma membrane; Intraflagellar transport; Hedgehog 'on' state; AURKA Activation by TPX2; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Hedgehog 'off' state; Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes Phagosome; Gap junction; Apoptosis 20 High Q9ERD7 Tubulin beta-3 chain OS=Mus musculus OX=10090 GN=Tubb3 PE=1 SV=1 0 148.252 59 22 221 5 450 50.4 4.93 1 1 1 1 262096.0225 34485.25391 2 1 Met-loss [N-Term] cell differentiation;cell organization and biogenesis;cellular component movement cytoplasm;cytoskeleton;nucleus catalytic activity;nucleotide binding;protein binding;structural molecule activity "Pf00091, Pf03953, Pf10644" 22152 ENSMUSG00000062380.4 Tubb3 8 Intraflagellar transport; Hedgehog 'on' state; Hedgehog 'off' state Phagosome; Gap junction 2 High P01027 Complement C3 OS=Mus musculus OX=10090 GN=C3 PE=1 SV=3 0 206.966 42 56 171 56 1663 186.4 6.73 2 3 1 1 3 3 1 1 1537875.238 3836693.153 1528131.559 2856893.983 20 19 12 29 cell organization and biogenesis;coagulation;defense response;metabolic process;regulation of biological process;response to stimulus extracellular enzyme regulator activity;protein binding "Pf00207, Pf01759, Pf01821, Pf01835, Pf07677, Pf07678, Pf07703, Pf10569, Pf11974" 12266 ENSMUSG00000024164.15 C3 17 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Regulation of Complement cascade; Peptide ligand-binding receptors; G alpha (i) signalling events; Activation of C3 and C5; Post-translational protein phosphorylation; Alternative complement activation; Neutrophil degranulation; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Herpes simplex infection; Chagas disease (American trypanosomiasis); Staphylococcus aureus infection; Tuberculosis; Phagosome; Complement and coagulation cascades; Pertussis; Legionellosis; Systemic lupus erythematosus; Leishmaniasis; Viral carcinogenesis 0 High Q922F4 Tubulin beta-6 chain OS=Mus musculus OX=10090 GN=Tubb6 PE=1 SV=1 0 93.601 38 16 170 4 447 50.1 4.89 1 1 1 1 46692.89063 12843.52148 37587.95654 1 1 2 cell organization and biogenesis cytoplasm;cytoskeleton;nucleus catalytic activity;nucleotide binding;structural molecule activity "Pf00091, Pf03953, Pf10644" 67951 ENSMUSG00000001473.6 Tubb6 18 Intraflagellar transport; Hedgehog 'on' state; Hedgehog 'off' state Phagosome; Gap junction 0 High P47911 60S ribosomal protein L6 OS=Mus musculus OX=10090 GN=Rpl6 PE=1 SV=3 0 71.29 46 13 132 13 296 33.5 10.7 1 1 1 1 618190.4868 649478.4521 187041.6641 234469.8442 11 8 4 6 cell organization and biogenesis;metabolic process cytoplasm;membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity "Pf01159, Pf03868" 19988 ENSMUSG00000029614.13 Rpl6 5 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q9EQK5 Major vault protein OS=Mus musculus OX=10090 GN=Mvp PE=1 SV=4 0 101.539 45 26 112 26 861 95.9 5.59 9 8 2 1 9 9 2 1 3207660.547 4941878.247 2232292.726 1185261.786 22 25 16 19 cell proliferation;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;nucleus protein binding "Pf01145, Pf01505, Pf11978" 78388 Mvp 7 0 High P29341 Polyadenylate-binding protein 1 OS=Mus musculus OX=10090 GN=Pabpc1 PE=1 SV=2 0 66.718 26 16 102 11 636 70.6 9.5 2 1 1 2 1 1 500651.9531 521408.0313 93376.15625 382927.0791 9 8 1 7 metabolic process;regulation of biological process cytoplasm;cytosol;membrane;nucleus;spliceosomal complex protein binding;RNA binding "Pf00076, Pf00658, Pf13893, Pf14259" 18458 ENSMUSG00000022283.14 Pabpc1 15 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); AUF1 (hnRNP D0) binds and destabilizes mRNA; Translation initiation complex formation; Deadenylation of mRNA mRNA surveillance pathway; RNA degradation; RNA transport 6 High Q9WUB3 "Glycogen phosphorylase, muscle form OS=Mus musculus OX=10090 GN=Pygm PE=1 SV=3" 0 93.694 34 24 101 16 842 97.2 7.11 18 13 4 1 30 25 4 1 6246779.605 6535686.082 1782401.34 825476.2949 19 17 12 14 cellular homeostasis;metabolic process;response to stimulus cytoplasm;endoplasmic reticulum catalytic activity;nucleotide binding Pf00343 19309 ENSMUSG00000032648.14; ENSMUSG00000106877.3 Pygm 19; CHR_MG4249_PATCH Glycogen breakdown (glycogenolysis) Insulin signaling pathway; Metabolic pathways; Insulin resistance; Starch and sucrose metabolism; Glucagon signaling pathway 3 High P14869 60S acidic ribosomal protein P0 OS=Mus musculus OX=10090 GN=Rplp0 PE=1 SV=3 0 61.305 44 10 98 10 317 34.2 6.25 1 1 1 1 905080.0288 825671.0215 186111.8965 704740.0186 5 4 4 5 response to stimulus;transport cytoplasm;cytosol;endoplasmic reticulum;membrane;nucleus;ribosome RNA binding;structural molecule activity "Pf00428, Pf00466" 11837 ENSMUSG00000067274.10 Rplp0 5 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High E9PV24 Fibrinogen alpha chain OS=Mus musculus OX=10090 GN=Fga PE=1 SV=1 0 67.38 30 20 98 20 789 87.4 6.11 7 4 1 11 7 1 7636915.357 4157164.782 1076338.615 3297299.654 18 11 5 10 cell organization and biogenesis;coagulation;defense response;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;endoplasmic reticulum;extracellular metal ion binding;protein binding;structural molecule activity "Pf00147, Pf08702, Pf12160" 14161 ENSMUSG00000028001.16 Fga 3 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); p130Cas linkage to MAPK signaling for integrins; Post-translational protein phosphorylation; Integrin cell surface interactions; Regulation of TLR by endogenous ligand; Common Pathway of Fibrin Clot Formation; GRB2:SOS provides linkage to MAPK signaling for Integrins ; Platelet degranulation Platelet activation; Complement and coagulation cascades 0 High P14148 60S ribosomal protein L7 OS=Mus musculus OX=10090 GN=Rpl7 PE=1 SV=2 0 53.11 44 14 82 14 270 31.4 10.89 1 1 596548.2434 1119339.626 124619.7993 9 5 3 metabolic process cytoplasm;membrane;nucleus;ribosome DNA binding;protein binding;RNA binding;structural molecule activity "Pf00327, Pf08079" 19989 ENSMUSG00000043716.13 Rpl7 1 Ribosome 0 High P62869 Elongin-B OS=Mus musculus OX=10090 GN=Elob PE=1 SV=1 0 38.568 67 9 81 9 118 13.2 5.01 1 1 1 1 624702.231 919269.2822 196112.666 359029.0947 7 6 3 7 Acetyl [N-Term] metabolic process;regulation of biological process nucleus protein binding Pf00240 67673 ENSMUSG00000055839.5 Tceb2; Elob 17 RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Formation of RNA Pol II elongation complex ; Neddylation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Ubiquitin mediated proteolysis; HIF-1 signaling pathway; Pathways in cancer; Renal cell carcinoma 0 High A0A140T8M0 Immunoglobulin kappa variable 1-117 (Fragment) OS=Mus musculus OX=10090 GN=Igkv1-117 PE=4 SV=2 0 50.68 39 3 76 1 119 13.1 8.48 3 3 1 1 10 9 1 1 6794635.906 3202403.703 479837.7969 289784.9805 2 3 2 3 "Pf07679, Pf07686" 16098 ENSMUSG00000094335.2 Igkv1-117 6 0 High Q8CG14 Complement C1s-A subcomponent OS=Mus musculus OX=10090 GN=C1sa PE=2 SV=2 0 78.414 38 18 72 13 688 76.8 5.08 6 2 1 6 2 1 2744308.08 1143227.309 187381.7109 992199.3789 13 8 4 9 defense response;metabolic process;regulation of biological process;response to stimulus extracellular catalytic activity;metal ion binding;protein binding "Pf00084, Pf00089, Pf00431, Pf07645, Pf14670" 50908 C1s; C1s1 6 Staphylococcus aureus infection; Complement and coagulation cascades; Pertussis; Systemic lupus erythematosus 5 High P62830 60S ribosomal protein L23 OS=Mus musculus OX=10090 GN=Rpl23 PE=1 SV=1 0 33.514 52 8 68 8 140 14.9 10.51 1 1 1 1 105585.7324 325838.3916 45334.41406 679136.8645 2 5 1 5 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;ribosome protein binding;RNA binding;structural molecule activity Pf00238 65019; 100044627; 100862455 ENSMUSG00000071415.6 Rpl23; LOC100044627; LOC100862455 11; 17 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q91YQ5 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Mus musculus OX=10090 GN=Rpn1 PE=1 SV=1 0 107.623 47 21 67 21 608 68.5 6.46 1 1 57866.92578 179387.6177 86262.48242 615656.8989 2 5 2 11 metabolic process cytosol;endoplasmic reticulum;membrane catalytic activity;RNA binding Pf04597 103963 ENSMUSG00000030062.7 Rpn1 6 Metabolic pathways; N-Glycan biosynthesis; Protein processing in endoplasmic reticulum 0 High A0A075B680 Immunoglobulin heavy variable 1-62-2 OS=Mus musculus OX=10090 GN=Ighv1-62-2 PE=4 SV=1 0 56.529 86 7 66 7 100 11.2 8.43 5 4 1 9 7 1 9052919.736 16549671.86 1028656.859 5201950.371 7 6 1 4 "Pf00047, Pf07686" ENSMUSG00000096078.2; ENSMUSG00000096577.2 12 0 High H3BJU7 Rho guanine nucleotide exchange factor 2 OS=Mus musculus OX=10090 GN=Arhgef2 PE=1 SV=1 0 70.797 26 20 65 20 956 108.5 6.87 1 1 1 1 65753.50098 823004.0574 464678.0049 1173796.531 3 12 4 15 regulation of biological process;response to stimulus metal ion binding "Pf00130, Pf00169, Pf00621, Pf07649" ENSMUSG00000028059.15 3 0 High A0A0B4J1I0 Immunoglobulin kappa variable 1-110 (Fragment) OS=Mus musculus OX=10090 GN=Igkv1-110 PE=4 SV=5 0 39.569 39 3 61 1 119 13.1 8.91 2 2 1 1 6 6 1 1 10906473.38 12822863.61 2976816.25 2239606.68 4 4 2 4 response to stimulus Pf07686 628261; 381777 ENSMUSG00000093861.2 Bb1; Igkv1-110 6 2 High A0A075B5K2 Immunoglobulin kappa chain variable 9-124 OS=Mus musculus OX=10090 GN=Igkv9-124 PE=1 SV=7 0 39.066 36 4 61 4 95 10.4 5.01 2 1 1 11 4 1 5710594.979 2885620.91 478989.9063 465466.8853 5 5 1 5 "Pf00047, Pf07679, Pf07686" ENSMUSG00000096632.2 6 0 High E9QM38 Solute carrier family 12 member 2 OS=Mus musculus OX=10090 GN=Slc12a2 PE=1 SV=1 0 61.98 16 15 60 15 1206 130.6 6.52 4 1 6 1 146005.3357 3120201.281 362843.8672 559484.8291 4 13 7 11 cellular homeostasis;regulation of biological process;response to stimulus;transport membrane catalytic activity;nucleotide binding;protein binding;transporter activity "Pf00324, Pf08403, Pf13520" 20496 ENSMUSG00000024597.10 Slc12a2 18 Cation-coupled Chloride cotransporters Pancreatic secretion; Salivary secretion 0 High P59913 Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 OS=Mus musculus OX=10090 GN=Pcmtd1 PE=1 SV=1 0 23.291 22 8 55 8 357 40.7 5.66 2 1 1 1 2 1 1 1 581915.0195 901391.9531 838184.0293 663118.9277 7 7 6 6 metabolic process cytoplasm;membrane catalytic activity "Pf01135, Pf12847, Pf13847" 319263 ENSMUSG00000051285.17 Pcmtd1 1 0 High P35979 60S ribosomal protein L12 OS=Mus musculus OX=10090 GN=Rpl12 PE=1 SV=2 0 38.989 50 6 54 6 165 17.8 9.42 1 1 459766.4668 745685.7061 43314.89551 397489.3779 5 4 2 4 cell organization and biogenesis;metabolic process cytoplasm;membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity "Pf00298, Pf03946" 269261 ENSMUSG00000038900.17 Rpl12 2 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High P25444 40S ribosomal protein S2 OS=Mus musculus OX=10090 GN=Rps2 PE=1 SV=3 0 26.355 33 9 54 9 293 31.2 10.24 1 1 1 1 117667.6814 224401.5527 96376.7832 219978.0195 6 6 4 6 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity "Pf00333, Pf03719" 16898; 546298 ENSMUSG00000044533.15 Rps2; Rps2-ps13 17; X Ribosome 0 High A0A075B5N3 Immunoglobulin kappa variable 8-28 OS=Mus musculus OX=10090 GN=Igkv8-28 PE=1 SV=7 0 31.451 60 5 54 3 101 10.9 5.94 4 3 1 6 9 1 2981536.305 7042378.547 113600.625 179129.3379 4 4 2 2 "Pf07679, Pf07686" ENSMUSG00000094356.2 6 1 High Q6GSS7 Histone H2A type 2-A OS=Mus musculus OX=10090 GN=Hist2h2aa1 PE=1 SV=3 0 14.957 41 5 53 3 130 14.1 10.9 2 2 1 4 3 1 1884067.286 1521611.963 460383.8438 1015225.012 5 5 2 5 cell organization and biogenesis;regulation of biological process chromosome;nucleus DNA binding;protein binding "Pf00125, Pf00808" 319192; 15267 ENSMUSG00000063954.7; ENSMUSG00000064220.6 Hist2h2aa2; Hist2h2aa1 3 RMTs methylate histone arginines; Meiotic Recombination; Mus musculus biological processes; Ub-specific processing proteases; NoRC negatively regulates rRNA expression; UCH proteinases; Metalloprotease DUBs; Meiotic Synapsis Alcoholism; Systemic lupus erythematosus 2 High P83940 Elongin-C OS=Mus musculus OX=10090 GN=Eloc PE=1 SV=1 0 34.754 66 7 53 7 112 12.5 4.78 1 1 1 1 1 1 1 1 1402112.506 1627644.93 1029438.848 685134.4219 6 5 4 4 metabolic process;regulation of biological process nucleus catalytic activity;protein binding Pf03931 67923; 102642819 ENSMUSG00000079658.9 Tceb1; Eloc; LOC101056616; LOC102642819 1; 2 RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Formation of RNA Pol II elongation complex ; Interleukin-7 signaling; Neddylation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Ubiquitin mediated proteolysis; HIF-1 signaling pathway; Pathways in cancer; Renal cell carcinoma 0 High A0A140T8N0 Immunoglobulin kappa chain variable 9-120 (Fragment) OS=Mus musculus OX=10090 GN=Igkv9-120 PE=1 SV=2 0 32.626 32 5 53 5 117 12.8 4.88 3 5 1 7 7 1 4978027.918 6464804.102 683487.2813 5 5 4 "Pf07679, Pf07686" ENSMUSG00000094872.1 6 0 High A0A075B5R5 Immunoglobulin heavy variable 4-1 (Fragment) OS=Mus musculus OX=10090 GN=Ighv4-1 PE=1 SV=7 0 35.875 68 7 52 6 116 12.9 8.9 5 3 1 7 6 1 3390452.364 5758933.352 183225.2344 307332.394 6 4 3 5 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000076655.2 LOC668418 12 1 High P01670 Ig kappa chain V-III region PC 6684 OS=Mus musculus OX=10090 PE=1 SV=1 0 38.125 88 5 52 2 111 12 8 3 1 1 11 1 1 6427556.41 1489862.297 1795001 433116.9194 4 4 1 3 "Pf00047, Pf07679, Pf07686" 667914 Igkv3-12 6 2 High P06330 Ig heavy chain V region AC38 205.12 OS=Mus musculus OX=10090 PE=1 SV=1 0 38.684 72 5 52 3 118 12.9 7.11 4 3 1 1 12 3 1 1 47896749.17 31598049.84 2322864.883 4966612.746 6 6 3 4 "Pf00047, Pf07686" 380820 IghmAC38.205.12 12 1 High A0A140T8P5 Immunoglobulin kappa chain variable 8-24 (Fragment) OS=Mus musculus OX=10090 GN=Igkv8-24 PE=4 SV=2 0 28.85 36 4 51 2 121 13.3 5.94 4 3 1 1 7 5 1 1 2318803.25 781924.4141 133352.9844 100698.7734 2 2 1 1 Pf07679 677858 ENSMUSG00000076583.1 Igkv8-24 6 0 High P01897 "H-2 class I histocompatibility antigen, L-D alpha chain OS=Mus musculus OX=10090 GN=H2-L PE=1 SV=2" 0 48.354 38 11 50 2 362 40.7 6.25 1 1 92182.23438 2 defense response;regulation of biological process;response to stimulus cell surface;endoplasmic reticulum;Golgi;membrane protein binding;RNA binding "Pf00129, Pf06623, Pf07654, Pf08205" 14964 H2-D1 17 1 High Q9EQ20 "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Mus musculus OX=10090 GN=Aldh6a1 PE=1 SV=1" 0 38.227 38 13 49 13 535 57.9 8.07 2 2 1 4 4 1 1162531.25 1586235.229 414377.0625 537583.981 9 10 5 7 cell differentiation;metabolic process mitochondrion catalytic activity;RNA binding Pf00171 104776 ENSMUSG00000021238.10 Aldh6a1 12 Branched-chain amino acid catabolism "Valine, leucine and isoleucine degradation; Metabolic pathways; beta-Alanine metabolism; Propanoate metabolism; Inositol phosphate metabolism; Carbon metabolism" 0 High A0A0G2JFA8 Immunoglobulin kappa variable 17-121 (Fragment) OS=Mus musculus OX=10090 GN=Igkv17-121 PE=4 SV=4 0 18.046 33 2 48 2 117 12.9 4.36 2 2 1 8 6 1 12704770.35 17106560.53 1140242.207 2428156.441 3 3 2 3 response to stimulus "Pf00047, Pf07686" 667435 ENSMUSG00000076514.3 Igkv17-121 6 0 High P35564 Calnexin OS=Mus musculus OX=10090 GN=Canx PE=1 SV=1 0 50.754 27 12 47 12 591 67.2 4.64 1 1 5013.991211 327110.7832 1 7 metabolic process;transport cytoplasm;endoplasmic reticulum;membrane;ribosome metal ion binding;protein binding;RNA binding Pf00262 12330 ENSMUSG00000020368.15 Canx 11 "Calnexin/calreticulin cycle; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; MHC class II antigen presentation; Interleukin-35 Signalling" HTLV-I infection; Thyroid hormone synthesis; Phagosome; Antigen processing and presentation; Protein processing in endoplasmic reticulum 0 High E9Q1Z0 Keratin 90 OS=Mus musculus OX=10090 GN=Krt90 PE=1 SV=1 0 26.62 18 11 46 2 538 58.2 8.25 1 1 1 1 1 1 1951579.875 3817556.07 2314173.75 1822924.225 1 2 1 2 cell organization and biogenesis;metabolic process catalytic activity;motor activity;protein binding;structural molecule activity "Pf00038, Pf01576, Pf04111, Pf06810, Pf09728, Pf12128, Pf13166, Pf13514" 239673 ENSMUSG00000048699.4 4732456N10Rik; Krt90 15 1 High P01663 Ig kappa chain V-III region PC 4050 OS=Mus musculus OX=10090 PE=1 SV=1 0 36.593 53 3 46 1 111 12 5.06 3 1 1 1 7 3 2 1 6305951.813 1280793.145 1749382.453 539565.8379 2 2 1 2 "Pf00047, Pf07679, Pf07686, Pf13927" 0 High A0A2R8VHP3 Predicted pseudogene 5478 OS=Mus musculus OX=10090 GN=Gm5478 PE=1 SV=1 0 18.77 11 7 45 3 535 57.9 6.2 3 3 1 1 3 4 1 1 644004.9934 4025896.563 121697.207 799780.9531 3 2 2 2 0 High Q64475 Histone H2B type 1-B OS=Mus musculus OX=10090 GN=H2bc3 PE=1 SV=3 0 31.198 48 7 43 7 126 13.9 10.32 3 1 1 4 1 1 2196157.66 1221481.449 422722.6328 847551.2461 7 5 4 6 cell organization and biogenesis chromosome;cytosol;nucleus DNA binding;protein binding "Pf00125, Pf00808" 319178 ENSMUSG00000075031.3 Hist1h2bb 13 HATs acetylate histones; E3 ubiquitin ligases ubiquitinate target proteins; Meiotic Recombination; Mus musculus biological processes; NoRC negatively regulates rRNA expression; Meiotic Synapsis Alcoholism; Systemic lupus erythematosus; Viral carcinogenesis 0 High A0A075B5T2 Immunoglobulin heavy variable 6-3 (Fragment) OS=Mus musculus OX=10090 GN=Ighv6-3 PE=4 SV=7 0 43.965 43 5 42 3 118 13.3 7.84 2 1 1 4 1 1 512213.875 37608.33203 40219.37891 197868.5352 3 1 1 3 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding "Pf07679, Pf07686" ENSMUSG00000076677.1 12 0 High A0A075B5Y4 Immunoglobulin heavy variable 1-81 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-81 PE=4 SV=1 0 27.003 59 6 40 3 117 13 8.79 2 2 1 1 3 3 1 1 3518811.978 2016561.969 489574.5156 730550.7695 4 5 2 5 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000094689.1 12 3 High Q9JJY4 Probable ATP-dependent RNA helicase DDX20 OS=Mus musculus OX=10090 GN=Ddx20 PE=1 SV=2 0 41.481 28 15 40 15 825 91.7 6.74 4 1 1 5 1 1 2739.97168 2759892.098 650864.377 1311112.653 1 12 6 10 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;cytosol;membrane;nucleus catalytic activity;DNA binding;nucleotide binding;protein binding "Pf00270, Pf00271" 53975 ENSMUSG00000027905.15 Ddx20 3 snRNP Assembly RNA transport 0 High P01901 "H-2 class I histocompatibility antigen, K-B alpha chain OS=Mus musculus OX=10090 GN=H2-K1 PE=1 SV=1" 0 52.499 46 12 39 5 369 41.3 6.39 1 1 98996.75 189434.7168 265519.6338 1 2 6 defense response;regulation of biological process;response to stimulus cell surface;endoplasmic reticulum;Golgi;membrane protein binding;RNA binding "Pf00129, Pf06623, Pf07654" 14972 ENSMUSG00000061232.15 H2-K1 17 Endocytosis; Herpes simplex infection; Allograft rejection; Epstein-Barr virus infection; Cell adhesion molecules (CAMs); HTLV-I infection; Phagosome; Graft-versus-host disease; Viral myocarditis; Antigen processing and presentation; Type I diabetes mellitus; Natural killer cell mediated cytotoxicity; Autoimmune thyroid disease; Viral carcinogenesis 5 High P01660 Ig kappa chain V-III region PC 3741/TEPC 111 OS=Mus musculus OX=10090 PE=1 SV=1 0 27.29 49 3 39 1 111 12.1 5.38 3 1 1 10 1 1 1301716.524 197785.6758 110987.4453 114607.4883 2 1 1 1 "Pf00047, Pf07679, Pf07686" LOC676215 1 High Q6P6L6 Gem (Nuclear organelle) associated protein 4 OS=Mus musculus OX=10090 GN=Gemin4 PE=1 SV=1 0 35.207 16 12 38 12 1058 120.1 5.15 1 1 1 1 1248337.572 433419.6885 1084384.222 10 6 10 cell organization and biogenesis;metabolic process cytosol;membrane 276919 ENSMUSG00000049396.6 Gemin4 11 snRNP Assembly RNA transport 0 High O70325 Phospholipid hydroperoxide glutathione peroxidase OS=Mus musculus OX=10090 GN=Gpx4 PE=1 SV=4 0 25.15 36 6 37 6 197 22.2 8.46 1 1 343609.084 592570.1484 32577.50293 586121.9961 7 5 2 6 cell organization and biogenesis;development;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus antioxidant activity;catalytic activity;protein binding Pf00255 625249 ENSMUSG00000075706.10 Gpx4 10 Synthesis of 12-eicosatetraenoic acid derivatives; Synthesis of 15-eicosatetraenoic acid derivatives Glutathione metabolism 0 High P01801 Ig heavy chain V-III region J606 OS=Mus musculus OX=10090 PE=1 SV=1 0 52.304 47 6 36 3 115 12.8 7.12 1 1 1 3 1 1 2757748.595 1547308.119 193733.542 839536.0215 6 5 3 6 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 238427 Ighv6-6 12 5 High Q8VED5 "Keratin, type II cytoskeletal 79 OS=Mus musculus OX=10090 GN=Krt79 PE=1 SV=2" 0 16.358 10 6 35 1 531 57.5 7.69 2 1 1 1 2 1 1 1 483521.0625 1172464.748 566011.4375 768589.4375 1 2 1 1 catalytic activity;motor activity;protein binding;structural molecule activity "Pf00038, Pf01576, Pf13166" 223917 ENSMUSG00000061397.7 Krt79 15 Formation of the cornified envelope 0 High A0A075B5N7 Immunoglobulin kappa variable 6-13 OS=Mus musculus OX=10090 GN=Igkv6-13 PE=1 SV=7 0 20.114 58 5 35 3 95 10.4 6.51 4 3 1 6 5 1 14899429.05 6692085.922 523170.875 1363104.367 4 4 3 4 "Pf00047, Pf07679, Pf07686" ENSMUSG00000076594.2 6 2 High A0A140T8N9 Immunoglobulin kappa variable 6-32 (Fragment) OS=Mus musculus OX=10090 GN=Igkv6-32 PE=4 SV=2 0 30.252 40 4 35 3 115 12.6 7.85 4 3 1 9 5 1 2316604.232 760154.7969 240358.8594 342993.5156 4 3 2 3 "Pf00047, Pf07679, Pf07686" 434039 ENSMUSG00000076576.2 Igkv6-32 6 0 High A0A140T8M9 Immunoglobulin kappa chain variable 1-122 (Fragment) OS=Mus musculus OX=10090 GN=Igkv1-122 PE=4 SV=2 0 6.731 17 2 34 1 119 13.1 7.99 1 1 1 1 4 4 1 1 53377.17969 1 Pf07686 434024 ENSMUSG00000095497.2 Igkv1-122 6 0 High A0A075B5Q4 Immunoglobulin heavy variable 5-12 (Fragment) OS=Mus musculus OX=10090 GN=Ighv5-12 PE=4 SV=1 0 13.489 32 4 33 3 117 13.1 8.85 4 3 1 7 5 1 3659346.969 4170957.531 384743.7266 4 3 2 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000095429.1 LOC674114 12 1 High O54991 Contactin-associated protein 1 OS=Mus musculus OX=10090 GN=Cntnap1 PE=1 SV=2 0 37.836 13 14 33 14 1385 156.2 7.06 1 1 17829.85449 10964.2417 181494.2852 2 2 8 cell organization and biogenesis membrane protein binding "Pf00054, Pf00147, Pf00754, Pf02210" 53321 ENSMUSG00000017167.6 Cntnap1 11 Cell adhesion molecules (CAMs) 0 High P06328 Ig heavy chain V region 1-72 OS=Mus musculus OX=10090 GN=Ighv1-72 PE=1 SV=2 0 14.087 30 4 32 2 117 12.9 9.29 3 2 1 5 2 1 4825146.613 2258968.495 501808.8906 592355.875 3 3 1 1 2 High P01633 Ig kappa chain V19-17 OS=Mus musculus OX=10090 GN=Igk-V19-17 PE=1 SV=1 0 20.848 31 4 32 1 149 16.4 6.92 3 4 1 7 5 1 2168996 257902.9688 161788.2813 298650.375 1 1 1 1 response to stimulus membrane Pf07686 667865 Igkv6-17 6 1 High P01667 Ig kappa chain V-III region PC 6308 OS=Mus musculus OX=10090 PE=1 SV=1 0 19.621 53 3 32 2 111 12.1 4.61 2 1 1 8 1 1 521547.5313 44586.41406 1 1 "Pf00047, Pf07679, Pf07686" 0 Medium O54988 STE20-like serine/threonine-protein kinase OS=Mus musculus OX=10090 GN=Slk PE=1 SV=2 0.011 2.171 1 1 29 1 1233 141.4 5.14 1 1 2 1 43267747.02 81587128.47 78663029.82 71805898.45 1 1 1 1 cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm catalytic activity;nucleotide binding;protein binding "Pf00069, Pf07714, Pf12474, Pf14531" 20874 ENSMUSG00000025060.14 Slk 19 Oocyte meiosis 0 High P01668 Ig kappa chain V-III region PC 7210 OS=Mus musculus OX=10090 PE=1 SV=1 0 20.314 54 3 29 2 110 11.9 4.75 2 1 1 9 1 1 733417.5625 135422.5625 43491.07813 1 1 1 "Pf00047, Pf07679, Pf07686" 0 High P62270 40S ribosomal protein S18 OS=Mus musculus OX=10090 GN=Rps18 PE=1 SV=3 0 17.486 39 7 29 7 152 17.7 10.99 2 1 2 1 339181.958 783237.1016 774880.7832 437366.9063 4 3 4 4 metabolic process cytoplasm;cytosol;membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity Pf00416 20084 ENSMUSG00000008668.14 Rps18 17 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High P01642 Ig kappa chain V-V region L7 (Fragment) OS=Mus musculus OX=10090 GN=Gm10881 PE=1 SV=1 0 17.403 29 3 29 3 115 12.6 5.94 3 1 1 8 3 1 3853557.938 2361773.281 294698.9102 307642.207 3 3 2 2 response to stimulus "Pf00047, Pf07679, Pf07686" 619846; 434037 ENSMUSG00000076563.2 Igkv5-48; Igkv12-47 6 0 High P04223 "H-2 class I histocompatibility antigen, K-K alpha chain OS=Mus musculus OX=10090 GN=H2-K1 PE=1 SV=1" 0 32.708 29 8 28 2 369 41.6 7.03 1 1 defense response;regulation of biological process;response to stimulus cell surface;endoplasmic reticulum;Golgi;membrane protein binding;RNA binding "Pf00129, Pf06623, Pf07654" 14972 H2-K1 17 0 High P01900 "H-2 class I histocompatibility antigen, D-D alpha chain OS=Mus musculus OX=10090 GN=H2-D1 PE=1 SV=1" 0 22.358 20 6 27 2 365 41.1 6.65 1 1 5221.942627 702444.3271 5334.57666 17435.41602 1 2 1 1 regulation of biological process;response to stimulus cell surface;endoplasmic reticulum;Golgi;membrane protein binding;RNA binding "Pf00129, Pf06623, Pf07654, Pf08205" 14964; 102641613 LOC101056446; H2-D1; LOC102641613 17 0 Medium Q7SIG6 "Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 OS=Mus musculus OX=10090 GN=Asap2 PE=1 SV=3" 0.013 2.006 1 1 26 1 958 106.7 6.65 1 1 1 1 2 2 1 1 560525.8125 2278531.5 511705.9375 637082.4375 1 1 1 1 regulation of biological process cytoplasm;Golgi;membrane enzyme regulator activity;metal ion binding;protein binding "Pf00018, Pf00023, Pf00169, Pf01412, Pf07653, Pf12796, Pf13637, Pf13857, Pf14604" 211914 ENSMUSG00000052632.15 Asap2 12 Endocytosis; Fc gamma R-mediated phagocytosis 0 High A0A1W2P7F1 "Complement component 1, s subcomponent 2 OS=Mus musculus OX=10090 GN=C1s2 PE=3 SV=1" 0 24.453 13 6 26 1 694 77.2 4.94 3 1 1 3 1 1 180118.3125 83046.45313 148313.75 1 1 1 defense response;metabolic process;regulation of biological process;response to stimulus extracellular catalytic activity;metal ion binding;protein binding "Pf00084, Pf00089, Pf00431, Pf07645, Pf14670" 317677 ENSMUSG00000079343.4 Gm5077; C1s2 6 Staphylococcus aureus infection; Complement and coagulation cascades; Pertussis; Systemic lupus erythematosus 0 High Q9D6M3 Mitochondrial glutamate carrier 1 OS=Mus musculus OX=10090 GN=Slc25a22 PE=1 SV=1 0 27.084 32 8 25 8 323 34.6 9.09 1 1 52508.68164 65586.80078 19434.90186 353117.4072 3 5 2 6 transport membrane;mitochondrion transporter activity Pf00153 68267 ENSMUSG00000019082.18 Slc25a22 7 Organic anion transporters 0 High Q99KV1 DnaJ homolog subfamily B member 11 OS=Mus musculus OX=10090 GN=Dnajb11 PE=1 SV=1 0 47.85 31 9 25 9 358 40.5 6.32 1 1 4577.680176 35318.875 399759.6523 1 1 5 metabolic process;regulation of biological process cytoplasm;endoplasmic reticulum;membrane;nucleus;organelle lumen protein binding "Pf00226, Pf01556" 67838 ENSMUSG00000004460.16 Dnajb11 16 Protein processing in endoplasmic reticulum 0 High A0A0G2JFZ3 Immunoglobulin kappa chain variable 19-93 (Fragment) OS=Mus musculus OX=10090 GN=Igkv19-93 PE=1 SV=4 0 11.69 30 3 25 2 115 12.8 8.29 2 1 1 5 4 1 4583030.281 1089682.281 474591.7578 433145.3906 3 2 2 2 response to stimulus "Pf00047, Pf07679, Pf07686" 692161 ENSMUSG00000098814.2 Igkv19-93 6 1 High P63101 14-3-3 protein zeta/delta OS=Mus musculus OX=10090 GN=Ywhaz PE=1 SV=1 0 13.439 32 7 25 5 245 27.8 4.79 1 1 1 1 36729.42725 150617.4736 17340 64054.02734 4 3 1 3 Acetyl [N-Term] cell organization and biogenesis;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;membrane;mitochondrion;nucleus protein binding;RNA binding Pf00244 22631 ENSMUSG00000022285.16 Ywhaz 15 "Translocation of GLUT4 to the plasma membrane; Activation of BAD and translocation to mitochondria ; Deactivation of the beta-catenin transactivating complex; RHO GTPases activate PKNs; Rap1 signalling; KSRP (KHSRP) binds and destabilizes mRNA; GP1b-IX-V activation signalling; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; Interleukin-3, 5 and GM-CSF signaling" Epstein-Barr virus infection; Hippo signaling pathway; Hepatitis B; Oocyte meiosis; Cell cycle; PI3K-Akt signaling pathway; Viral carcinogenesis 0 High Q3V117 ATP-citrate synthase OS=Mus musculus OX=10090 GN=Acly PE=1 SV=1 0 28.721 13 10 24 10 1101 120.7 7.44 4 1 1 5 1 1 1596723.153 564794.2148 151109.126 368395.8213 8 5 3 5 metabolic process cytoplasm;cytosol;membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00285, Pf00549, Pf02629, Pf08442" 104112 ENSMUSG00000020917.17 Acly 11 0 High P18531 Ig heavy chain V region 3-6 OS=Mus musculus OX=10090 GN=Ighv3-6 PE=1 SV=1 0 13.787 22 2 24 2 116 13.1 8.78 1 1 1 3 5 1 1727977.938 2779555.359 53810.38672 252700.7544 3 2 1 2 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 780829 ENSMUSG00000076672.7 Gm16932; Ighv3-6 12 Regulation of Complement cascade; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Cell surface interactions at the vascular wall; FCERI mediated NF-kB activation; Role of LAT2/NTAL/LAB on calcium mobilization; Role of phospholipids in phagocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR activation; Classical antibody-mediated complement activation; FCERI mediated Ca+2 mobilization; FCERI mediated MAPK activation; CD22 mediated BCR regulation; Scavenging of heme from plasma 0 High P01746 Ig heavy chain V region 93G7 OS=Mus musculus OX=10090 PE=2 SV=1 0 7.96 17 2 23 1 140 15.5 8.4 2 1 1 4 2 1 2538992 1193029.75 260797.4688 171809.2031 1 1 1 1 Pf07686 238440 LOC238440 12 0 High A0A075B5T3 Immunoglobulin heavy variable 6-6 (Fragment) OS=Mus musculus OX=10090 GN=Ighv6-6 PE=4 SV=1 0 33.944 66 6 23 3 119 13.3 7.08 1 1 1 1 1 1 503687.5586 179598.1758 413641.1484 374344.3711 3 2 2 3 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000076680.1 LOC677040 12 1 High A0A075B5T6 Immunoglobulin heavy variable V10-3 (Fragment) OS=Mus musculus OX=10090 GN=Ighv10-3 PE=4 SV=1 0 16.194 40 5 21 3 119 13.5 8.87 5 1 8 1 2994871.031 299433.4063 125411.8262 107758.5098 5 4 3 2 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000095700.2 LOC633728 12 2 High A0A0B4J1I1 Immunoglobulin kappa variable 16-104 (Fragment) OS=Mus musculus OX=10090 GN=Igkv16-104 PE=4 SV=1 0 19.739 23 2 21 2 116 12.9 7.08 2 1 1 3 1 1 3112619.875 1311080.367 380261.6094 2 1 1 response to stimulus "Pf00047, Pf07679, Pf07686" 381778 ENSMUSG00000076522.2 Igkv16-104 6 0 High P62259 14-3-3 protein epsilon OS=Mus musculus OX=10090 GN=Ywhae PE=1 SV=1 0 13.092 24 6 21 4 255 29.2 4.74 1 1 1 1 175568.5938 72060.16797 26005.9668 4 2 1 Acetyl [N-Term] cellular component movement;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;protein binding;RNA binding Pf00244 22627 ENSMUSG00000020849.13 Ywhae 11 Activation of BAD and translocation to mitochondria ; Loss of Nlp from mitotic centrosomes; Recruitment of NuMA to mitotic centrosomes; TP53 Regulates Metabolic Genes; Signaling by Hippo; Translocation of GLUT4 to the plasma membrane; Anchoring of the basal body to the plasma membrane; Regulation of HSF1-mediated heat shock response; AURKA Activation by TPX2; RHO GTPases activate PKNs; Recruitment of mitotic centrosome proteins and complexes; HSF1 activation; RAB GEFs exchange GTP for GDP on RABs; Regulation of PLK1 Activity at G2/M Transition; NADE modulates death signalling; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; Signalling by NGF Epstein-Barr virus infection; Hippo signaling pathway; Oocyte meiosis; Neurotrophin signaling pathway; Cell cycle; PI3K-Akt signaling pathway; Viral carcinogenesis 0 High P23953 Carboxylesterase 1C OS=Mus musculus OX=10090 GN=Ces1c PE=1 SV=4 0 38.897 19 9 21 7 554 61 5.06 1 1 96842.84375 49516.11719 401762.959 1 1 2 metabolic process endoplasmic reticulum;organelle lumen catalytic activity "Pf00135, Pf07859" 13884 ENSMUSG00000057400.14 Ces1c 8 Phase I - Functionalization of compounds Metabolic pathways; Drug metabolism - other enzymes 2 High Q99MR8 "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial OS=Mus musculus OX=10090 GN=Mccc1 PE=1 SV=2" 0 23.311 16 9 21 9 717 79.3 7.83 4 3 1 5 4 1 1141669.682 1593421.133 237777.2109 694359.4727 7 6 4 5 metabolic process membrane;mitochondrion;organelle lumen catalytic activity;metal ion binding;nucleotide binding "Pf00289, Pf00364, Pf01071, Pf02222, Pf02785, Pf02786, Pf07478, Pf13533, Pf13535, Pf15632" 72039 ENSMUSG00000027709.9 Mccc1 3 Biotin transport and metabolism; Branched-chain amino acid catabolism "Valine, leucine and isoleucine degradation; Metabolic pathways" 0 High Q9QZN4 F-box only protein 6 OS=Mus musculus OX=10090 GN=Fbxo6 PE=1 SV=1 0 19.719 32 7 20 7 295 34.5 8.18 1 1 1 1 456450.166 94767.16211 383161.1455 5 3 5 metabolic process;response to stimulus cytoplasm catalytic activity;protein binding "Pf00646, Pf04300, Pf12937" 50762 ENSMUSG00000055401.14 Fbxo6 4 Neddylation; Antigen processing: Ubiquitination & Proteasome degradation Protein processing in endoplasmic reticulum 0 High A0A0B4J1J6 Immunoglobulin heavy variable 10-1 (Fragment) OS=Mus musculus OX=10090 GN=Ighv10-1 PE=4 SV=1 0 17.076 40 5 20 3 119 13.5 8.59 5 1 8 1 1815965.035 691705.9531 236436.5625 369331.4102 4 3 3 2 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding 16050 ENSMUSG00000095981.1 Igh-V10 12 0 High P04940 Ig kappa chain V-VI region NQ2-17.4.1 OS=Mus musculus OX=10090 PE=2 SV=1 0 14.863 34 4 20 2 107 11.6 9.36 2 1 3 1 5056185.5 678800.1563 557091.2266 749402.5215 4 3 2 2 "Pf00047, Pf07679, Pf07686" 2 High A0A075B5R2 Immunoglobulin heavy variable 7-3 (Fragment) OS=Mus musculus OX=10090 GN=Ighv7-3 PE=4 SV=2 0 20.131 40 4 20 4 120 13.4 8.6 2 1 1 1 3 1 1 1 1924606.844 366860.8438 133071.0781 136552.7344 4 3 1 2 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000076652.4 12 0 High P62264 40S ribosomal protein S14 OS=Mus musculus OX=10090 GN=Rps14 PE=1 SV=3 0 26.266 41 8 20 8 151 16.3 10.05 1 1 1 1 69204.12305 509246.4531 337917.416 4 3 6 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process membrane;mitochondrion;ribosome RNA binding;structural molecule activity;translation regulator activity Pf00411 20044 ENSMUSG00000024608.10 Rps14 18 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High B1AU25 "Apoptosis-inducing factor 1, mitochondrial OS=Mus musculus OX=10090 GN=Aifm1 PE=1 SV=1" 0 19.855 12 5 19 5 608 66.1 9.11 1 1 302465.0977 354361.9121 94483.08594 269704.168 3 4 1 5 cell death;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;DNA binding;nucleotide binding;protein binding "Pf00070, Pf07992, Pf14721, Pf14962" 26926 ENSMUSG00000036932.14 Aifm1 X 0 High Q3ULD5 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Mus musculus OX=10090 GN=Mccc2 PE=1 SV=1" 0 32.735 31 11 19 11 563 61.3 8 6 3 1 1 6 3 1 1 2312106.947 1673399.773 798238.9058 1068740.793 9 6 7 9 metabolic process mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf01039, Pf03255" 78038 ENSMUSG00000021646.8 Mccc2 13 Biotin transport and metabolism; Branched-chain amino acid catabolism "Valine, leucine and isoleucine degradation; Metabolic pathways" 0 High P97742 "Carnitine O-palmitoyltransferase 1, liver isoform OS=Mus musculus OX=10090 GN=Cpt1a PE=1 SV=4" 0 30.568 15 9 19 8 773 88.2 8.62 1 1 43972.09766 247200.5 16935.02734 11181.94043 1 1 1 1 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport membrane;mitochondrion catalytic activity;protein binding Pf00755 12894 ENSMUSG00000024900.4 Cpt1a 19 Circadian Clock; Mus musculus biological processes; Signaling by Retinoic Acid; Rora activates gene expression; Import of palmitoyl-CoA into the mitochondrial matrix PPAR signaling pathway; Fatty acid metabolism; Fatty acid degradation; Insulin resistance; Adipocytokine signaling pathway; AMPK signaling pathway; Glucagon signaling pathway 0 High P12382 "ATP-dependent 6-phosphofructokinase, liver type OS=Mus musculus OX=10090 GN=Pfkl PE=1 SV=4" 0 26.504 19 9 19 7 780 85.3 7.17 1 1 168962.8018 143020.9951 71992.40918 337982.123 6 5 4 8 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane catalytic activity;metal ion binding;nucleotide binding;protein binding Pf00365 18641 ENSMUSG00000020277.10 Pfkl 10 Neutrophil degranulation; Glycolysis RNA degradation; Metabolic pathways; Biosynthesis of amino acids; Glycolysis / Gluconeogenesis; Pentose phosphate pathway; HIF-1 signaling pathway; AMPK signaling pathway; Carbon metabolism; Fructose and mannose metabolism; Galactose metabolism; Central carbon metabolism in cancer; Glucagon signaling pathway 2 High A0A1B0GR78 Stromal interaction molecule 1 OS=Mus musculus OX=10090 GN=Stim1 PE=1 SV=1 0 24.461 16 6 18 6 540 62.2 6.39 1 1 35145.32056 29813.17969 5150.12793 349025.5977 3 1 1 6 cell differentiation;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;endoplasmic reticulum;membrane metal ion binding;protein binding;transporter activity "Pf00430, Pf04111, Pf07647, Pf09731" 20866 ENSMUSG00000030987.5 Stim1 7 0 High Q99M87 "DnaJ homolog subfamily A member 3, mitochondrial OS=Mus musculus OX=10090 GN=Dnaja3 PE=1 SV=1" 0 15.68 16 5 18 5 480 52.4 9.22 1 1 58171.2876 381570.8125 51465.86523 383675.2891 3 3 2 5 cell death;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus;organelle lumen enzyme regulator activity;metal ion binding;nucleotide binding;protein binding "Pf00226, Pf00684, Pf01556" 83945 ENSMUSG00000004069.16 Dnaja3 16 Viral carcinogenesis 0 High P68254 14-3-3 protein theta OS=Mus musculus OX=10090 GN=Ywhaq PE=1 SV=1 0 18.897 40 8 18 6 245 27.8 4.78 1 1 1 1 171473.4434 469851.125 201795.6523 348326.209 5 3 2 3 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;Golgi;membrane catalytic activity;DNA binding;protein binding Pf00244 22630; 102634437; 214444 ENSMUSG00000076432.12 Ywhaq; LOC102634437; Gm11226; Ywhaq-ps3; Cdk5rap2 12; 4 Translocation of GLUT4 to the plasma membrane; Activation of BAD and translocation to mitochondria ; RHO GTPases activate PKNs; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex Epstein-Barr virus infection; Hippo signaling pathway; Hepatitis B; Oocyte meiosis; Cell cycle; PI3K-Akt signaling pathway; Viral carcinogenesis 2 High A0A0A6YVW3 Immunoglobulin heavy variable V1-23 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-23 PE=4 SV=1 0 12.359 26 3 17 1 117 12.9 6.51 1 2 1 1 2 1 187420.0938 295712.9375 331733.5625 1 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000103290.1 12 0 Low P97302 Transcription regulator protein BACH1 OS=Mus musculus OX=10090 GN=Bach1 PE=1 SV=1 0.053 1.323 1 1 17 1 739 81.3 5.01 1 1 2129282.703 1480541 1253351.578 1702084.547 1 1 1 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;nucleus catalytic activity;DNA binding;protein binding "Pf00170, Pf00651, Pf03131, Pf07716" 12013 ENSMUSG00000025612.5 Bach1 16 0 High Q9D8L3 "Signal sequence receptor, delta OS=Mus musculus OX=10090 GN=Ssr4 PE=1 SV=1" 0 20.155 32 5 17 5 173 19 5.78 1 1 58237.24219 69425.67188 414686.2539 1 2 4 endoplasmic reticulum;membrane Pf05404 20832 ENSMUSG00000002014.12 Ssr4 X 0 High J3QK03 Immunoglobulin heavy variable V6-5 OS=Mus musculus OX=10090 GN=Ighv6-5 PE=4 SV=1 0 28 30 3 15 0 99 11.1 5.12 1 1 2 1 ENSMUSG00000096407.2 12 0 High P16045 Galectin-1 OS=Mus musculus OX=10090 GN=Lgals1 PE=1 SV=3 0 8.361 20 2 15 2 135 14.9 5.49 1 1 1 1 1 1 297904.6523 21335.64453 138038.5273 2 1 2 Met-loss+Acetyl [N-Term] cell death;cell differentiation;cellular homeostasis;regulation of biological process;response to stimulus cell surface;cytoplasm;cytosol;extracellular;nucleus protein binding;RNA binding;signal transducer activity Pf00337 16852 ENSMUSG00000068220.5 Lgals1 15 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation 0 High Q9CQR4 Acyl-coenzyme A thioesterase 13 OS=Mus musculus OX=10090 GN=Acot13 PE=1 SV=1 0 12.41 44 4 15 4 140 15.2 8.82 4 2 1 6 3 1 2018549.391 1831916.023 290918.3516 307897.9238 4 4 2 4 cell organization and biogenesis cytoplasm;cytoskeleton;cytosol;mitochondrion;nucleus catalytic activity Pf03061 66834 ENSMUSG00000006717.6 Acot13 13 Mitochondrial Fatty Acid Beta-Oxidation 0 High Q91VT4 Carbonyl reductase family member 4 OS=Mus musculus OX=10090 GN=Cbr4 PE=1 SV=2 0 30.695 31 6 15 6 236 25.4 9.69 1 1 1 1 362168.8281 434433.7832 70992.05078 607440.8281 5 4 1 4 cell organization and biogenesis;metabolic process mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf00106, Pf03435, Pf08659, Pf13561" 234309 ENSMUSG00000031641.14 Cbr4 8 Fatty acyl-CoA biosynthesis 0 Medium F6T4M4 Serine/arginine repetitive matrix protein 1 (Fragment) OS=Mus musculus OX=10090 GN=Srrm1 PE=1 SV=1 0.024 1.627 6 1 14 1 140 16.2 5.38 1 1 1 1 2 2 1 1 3010437 8527224 794828 1279715.5 1 1 1 1 metabolic process Pf01480 ENSMUSG00000028809.16 4 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript 0 High Q8C605 ATP-dependent 6-phosphofructokinase OS=Mus musculus OX=10090 GN=Pfkp PE=1 SV=1 0 16.518 7 4 12 2 784 85.5 6.89 1 1 1836.776611 16908.1123 2738 1 2 1 cell organization and biogenesis;metabolic process cytoplasm;cytosol;membrane;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding Pf00365 56421 ENSMUSG00000021196.13 Pfkp 13 RNA degradation; Metabolic pathways; Biosynthesis of amino acids; Glycolysis / Gluconeogenesis; Thyroid hormone signaling pathway; Pentose phosphate pathway; AMPK signaling pathway; Carbon metabolism; Fructose and mannose metabolism; Galactose metabolism; Central carbon metabolism in cancer 0 High P68510 14-3-3 protein eta OS=Mus musculus OX=10090 GN=Ywhah PE=1 SV=2 0 8.467 16 4 11 1 246 28.2 4.89 1 1 1 1 275206.1875 996823.8125 74090.07813 36220.4375 1 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;membrane protein binding Pf00244 22629 ENSMUSG00000018965.11 Ywhah 5 Translocation of GLUT4 to the plasma membrane; Activation of BAD and translocation to mitochondria ; RHO GTPases activate PKNs; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex Epstein-Barr virus infection; Hippo signaling pathway; Oocyte meiosis; Cell cycle; PI3K-Akt signaling pathway; Viral carcinogenesis 0 High Q9CRB9 MICOS complex subunit Mic19 OS=Mus musculus OX=10090 GN=Chchd3 PE=1 SV=1 0 10.298 21 4 9 4 227 26.3 8.37 1 1 64293.02734 610849.125 199089.1016 207495.0078 1 2 2 2 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;membrane;mitochondrion;nucleus protein binding;structural molecule activity "Pf05300, Pf06747" 66075 ENSMUSG00000053768.13 Chchd3 6 0 High Q9Z2E9 Seipin OS=Mus musculus OX=10090 GN=Bscl2 PE=1 SV=2 0 6.589 14 3 9 3 383 43.1 6.14 3 3 1 3 5 1 695613.6875 2242581.906 108846.125 365543.7148 3 3 1 2 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process endoplasmic reticulum;membrane Pf06775 14705 ENSMUSG00000071657.12 Bscl2 19 0 High Q8JZQ2 AFG3-like protein 2 OS=Mus musculus OX=10090 GN=Afg3l2 PE=1 SV=1 0.004 2.755 2 2 8 2 802 89.5 8.6 1 1 1 1 6858.669922 7238650 3131077.75 4593406.676 1 1 1 2 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00004, Pf01434, Pf05496, Pf06068, Pf06480, Pf07724, Pf07728, Pf13191, Pf13401" 69597 ENSMUSG00000024527.9 Afg3l2 18 Processing of SMDT1 0 High A0A0G2JEI7 Immunoglobulin kappa chain variable 12-38 (Fragment) OS=Mus musculus OX=10090 GN=Igkv12-38 PE=4 SV=4 0 8.392 37 3 8 3 115 12.5 4.72 1 1 1 1 2 1 1133124.974 1032645.219 181796.5469 177710.9063 3 2 1 1 response to stimulus "Pf00047, Pf07679, Pf07686" 620050 ENSMUSG00000076570.6 Igkv12-38 6 0 High Q60847 Collagen alpha-1(XII) chain OS=Mus musculus OX=10090 GN=Col12a1 PE=2 SV=3 0 14.908 3 6 8 6 3120 340 5.64 2 4 1 2 4 1 390902.0283 676693.498 411562.293 567557.0742 6 6 4 6 cell differentiation extracellular protein binding "Pf00041, Pf00092, Pf13519" 12816 Col12a1 9 Collagen chain trimerization; Collagen degradation; Assembly of collagen fibrils and other multimeric structures Protein digestion and absorption 0 High Q924L1 LETM1 domain-containing protein 1 OS=Mus musculus OX=10090 GN=Letmd1 PE=1 SV=1 0 6.519 13 3 7 3 360 41.7 10.54 2 1 1 2 1 1 135858.2969 517935.3594 344272.7266 669173.9922 1 2 2 3 cellular homeostasis membrane;mitochondrion Pf07766 68614 ENSMUSG00000037353.8 Letmd1 15 0 High Q2HXL6 ER degradation-enhancing alpha-mannosidase-like protein 3 OS=Mus musculus OX=10090 GN=Edem3 PE=1 SV=2 0 8.83 6 4 7 4 931 104.1 5.06 1 1 2342.946289 224912.7617 1 2 metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;membrane;organelle lumen catalytic activity;metal ion binding "Pf01532, Pf02225" 66967 ENSMUSG00000043019.12 Edem3 1 ER Quality Control Compartment (ERQC) Protein processing in endoplasmic reticulum 0 Medium Q9CPN9 RIKEN cDNA 2210010C04 gene OS=Mus musculus OX=10090 GN=2210010C04Rik PE=1 SV=1 0.014 1.884 5 1 7 1 247 26.4 7.93 1 1 802579.125 598847.9375 761185.75 341677.6875 1 1 1 1 metabolic process catalytic activity Pf00089 67373 ENSMUSG00000029882.5 2210010C04Rik 6 Pancreatic secretion; Protein digestion and absorption; Influenza A; Neuroactive ligand-receptor interaction 0 Low E9PWI7 Expressed sequence C87414 OS=Mus musculus OX=10090 GN=C87414 PE=4 SV=1 0.058 1.289 3 1 6 1 475 55 8.41 1 1 382784.9688 1335484 231759.4531 362057.5313 1 1 1 1 regulation of biological process 381654 ENSMUSG00000070686.10 C87414 5 0 High Q99JB2 "Stomatin-like protein 2, mitochondrial OS=Mus musculus OX=10090 GN=Stoml2 PE=1 SV=1" 0 8.649 22 4 6 4 353 38.4 8.87 1 1 1 1 215780.8203 51809.48633 73510.75391 3 2 2 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;membrane;mitochondrion protein binding Pf01145 66592 ENSMUSG00000028455.15 Stoml2 4 Processing of SMDT1 0 High Q8VEK0 Cell cycle control protein 50A OS=Mus musculus OX=10090 GN=Tmem30a PE=1 SV=1 0 8.339 9 3 6 2 364 41 8.37 1 1 7545.918457 29154.89453 212211.2266 1 1 3 cell organization and biogenesis;regulation of biological process;transport endoplasmic reticulum;Golgi;membrane protein binding;transporter activity Pf03381 69981 ENSMUSG00000032328.12 Tmem30a 9 Neutrophil degranulation 1 High Q6P6J9 Thioredoxin domain-containing protein 15 OS=Mus musculus OX=10090 GN=Txndc15 PE=1 SV=1 0 14.074 11 2 5 2 344 38.1 4.77 1 1 46334.57813 30692.25391 207117.7813 1 1 1 cellular homeostasis;regulation of biological process membrane Pf00085 69672 ENSMUSG00000021497.9 Txndc15 13 0 Low D3Z4R1 Probable ATP-dependent DNA helicase HFM1 OS=Mus musculus OX=10090 GN=Hfm1 PE=3 SV=2 0.079 1.126 0 1 5 1 1434 161.3 7.85 1 1 1 1 441416.7813 439201.3125 509682.875 616626.0625 1 1 1 1 cell differentiation;metabolic process cytoplasm catalytic activity;DNA binding;nucleotide binding "Pf00270, Pf00271, Pf02889, Pf04851" 330149 ENSMUSG00000043410.16 Hfm1 5 0 Low A0A0R4J1T2 E3 ubiquitin-protein ligase TTC3 (Fragment) OS=Mus musculus OX=10090 GN=Ttc3 PE=1 SV=1 0.076 1.176 1 1 5 1 776 88.8 7.68 1 1 41899686.29 10633428.8 12496326.58 11245737.64 1 1 1 1 metabolic process;regulation of biological process cytosol;membrane;nucleus;vacuole catalytic activity;metal ion binding;protein binding "Pf00515, Pf13424, Pf13432" 22129 ENSMUSG00000040785.18 Ttc3 16 0 High Q9R1Q9 V-type proton ATPase subunit S1 OS=Mus musculus OX=10090 GN=Atp6ap1 PE=1 SV=1 0.005 2.934 6 2 3 2 463 51 5.92 1 1 11488.96191 1 cell death;cell organization and biogenesis;cellular homeostasis;regulation of biological process;response to stimulus;transport endoplasmic reticulum;membrane catalytic activity;nucleotide binding;protein binding;transporter activity Pf05827 54411 ENSMUSG00000019087.13 Atp6ap1 X Ion channel transport; Transferrin endocytosis and recycling; Insulin receptor recycling Rheumatoid arthritis; Metabolic pathways; Tuberculosis; Hepatitis B; Lysosome; Phagosome; Oxidative phosphorylation 0 High P70428 Exostosin-2 OS=Mus musculus OX=10090 GN=Ext2 PE=1 SV=2 0.002 5.035 4 2 3 2 718 82 6.65 1 1 24894.08789 191291.7344 1 2 cell differentiation;metabolic process endoplasmic reticulum;Golgi;membrane catalytic activity;metal ion binding;protein binding "Pf03016, Pf09258" 14043 ENSMUSG00000027198.16 Ext2 2 HS-GAG biosynthesis Metabolic pathways; Glycosaminoglycan biosynthesis - heparan sulfate / heparin 0 Low Q8R4D5 Transient receptor potential cation channel subfamily M member 8 OS=Mus musculus OX=10090 GN=Trpm8 PE=1 SV=3 0.072 1.213 1 1 3 1 1104 127.6 6.92 1 1 162145.209 513405.0313 207144.4688 237966.3394 1 1 1 1 cell organization and biogenesis;cellular homeostasis;response to stimulus;transport membrane catalytic activity;protein binding;transporter activity "Pf00520, Pf01757" 171382 ENSMUSG00000036251.16 Trpm8 1 TRP channels Inflammatory mediator regulation of TRP channels 0 Low E9PUK3 Formin-binding protein 1-like OS=Mus musculus OX=10090 GN=Fnbp1l PE=1 SV=1 0.083 1.083 1 1 3 1 551 63.9 6.27 1 1 1 1 1 1 1303600 528961.8125 691884.125 597852.75 1 1 1 1 cell organization and biogenesis;metabolic process;transport cytoplasm;cytoskeleton;membrane protein binding "Pf00018, Pf00611, Pf07653, Pf08239, Pf14604" 214459 ENSMUSG00000039735.15 Fnbp1l 3 Clathrin-mediated endocytosis 0 Medium D3YVZ5 Tubulin polyglutamylase TTLL5 OS=Mus musculus OX=10090 GN=Ttll5 PE=1 SV=1 0.011 2.189 2 1 3 1 1281 142.8 8.78 1 1 123311356 46355372 59842069 64473299 1 1 1 1 metabolic process "Pf02222, Pf03133, Pf08443" ENSMUSG00000012609.18 12 0 High Q9CPP6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 OS=Mus musculus OX=10090 GN=Ndufa5 PE=1 SV=3 0 5.867 14 1 3 1 116 13.4 8.1 1 1 12858.4231 319256.3633 27501.17383 151686.1719 1 1 1 1 cell organization and biogenesis;metabolic process;transport membrane;mitochondrion catalytic activity Pf04716 68202 ENSMUSG00000023089.12 Ndufa5 6 Complex I biogenesis 0 High Q6ZQI3 Malectin OS=Mus musculus OX=10090 GN=Mlec PE=1 SV=2 0.002 5.11 9 2 2 2 291 32.3 6.05 1 1 10822.70996 8412.860352 210686.9453 1 1 2 metabolic process endoplasmic reticulum;membrane protein binding Pf11721 109154 ENSMUSG00000048578.11 Mlec 5 N-glycan trimming in the ER and Calnexin/Calreticulin cycle; Neutrophil degranulation 0 High Q8C0L0 Thioredoxin-related transmembrane protein 4 OS=Mus musculus OX=10090 GN=Tmx4 PE=1 SV=2 0.005 2.977 9 2 2 2 335 37.1 4.37 1 1 179835.1875 1 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport endoplasmic reticulum;membrane catalytic activity Pf00085 52837 ENSMUSG00000034723.11 Tmx4 2 0 Low E9Q5E2 THO complex subunit 2-like OS=Mus musculus OX=10090 GN=Thoc2l PE=1 SV=1 0.073 1.212 1 1 2 1 1589 182.6 8.56 1 1 1903287.125 585984.7656 210293.6836 687613.6719 1 1 1 1 transport RNA binding "Pf08706, Pf11262, Pf11732" 100042165 ENSMUSG00000079065.3 BC005561 5 mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript 0 Medium P35487 "Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial OS=Mus musculus OX=10090 GN=Pdha2 PE=1 SV=1" 0.024 1.607 3 1 2 1 391 43.4 8.5 1 1 1 1 375905.1875 135951.5781 121651.2031 248704.9844 1 1 1 1 metabolic process mitochondrion;organelle lumen catalytic activity Pf00676 18598 ENSMUSG00000047674.2 Pdha2 3 Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Glyoxylate metabolism and glycine degradation Pyruvate metabolism; Citrate cycle (TCA cycle); Metabolic pathways; Glycolysis / Gluconeogenesis; HIF-1 signaling pathway; Carbon metabolism; Central carbon metabolism in cancer; Glucagon signaling pathway 0 High C0HK80 Adipocyte-related X-chromosome expressed sequence 2 OS=Mus musculus OX=10090 GN=Arxes2 PE=1 SV=1 0.004 3.425 11 2 2 2 180 20.1 9.6 1 1 459857.4453 2 cell differentiation;metabolic process;transport endoplasmic reticulum;membrane catalytic activity Pf04573 76219; 76976 ENSMUSG00000048040.8; ENSMUSG00000048355.2 Arxes1; Arxes2 X Protein export 0 High Q791V5 Mitochondrial carrier homolog 2 OS=Mus musculus OX=10090 GN=Mtch2 PE=1 SV=1 0 5.362 15 2 2 2 303 33.5 8.25 1 1 19080.51758 20756.64258 89056.96094 1 1 2 Met-loss+Acetyl [N-Term] cell death;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport membrane;mitochondrion;nucleus Pf00153 56428 ENSMUSG00000027282.17; ENSMUSG00000111714.1 Mtch2 2; CHR_MG191_PATCH 0 Medium Q8R5J9 PRA1 family protein 3 OS=Mus musculus OX=10090 GN=Arl6ip5 PE=1 SV=2 0.029 1.543 11 1 2 1 188 21.5 9.61 1 1 531107.5 1 regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;endoplasmic reticulum;membrane protein binding Pf03208 65106 ENSMUSG00000035199.6 Arl6ip5 6 Glutamate Neurotransmitter Release Cycle 0 High Q9CQU0 Thioredoxin domain-containing protein 12 OS=Mus musculus OX=10090 GN=Txndc12 PE=1 SV=1 0.002 3.793 14 2 2 2 170 19 5.26 1 1 93484.34375 1 cell differentiation;cellular homeostasis;metabolic process;regulation of biological process endoplasmic reticulum;organelle lumen catalytic activity "Pf00085, Pf13098, Pf13899" 66073 ENSMUSG00000028567.8 Txndc12 4 Glutathione metabolism 0 High Q8K3K7 1-acyl-sn-glycerol-3-phosphate acyltransferase beta OS=Mus musculus OX=10090 GN=Agpat2 PE=1 SV=1 0.002 4.505 10 2 2 2 278 31 8.88 1 1 51065.30078 267588.7109 2 2 metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;membrane catalytic activity Pf01553 67512 ENSMUSG00000026922.13 Agpat2 2 Neutrophil degranulation; Synthesis of PA Phospholipase D signaling pathway; Fat digestion and absorption; Metabolic pathways; Glycerophospholipid metabolism; Glycerolipid metabolism 0 Medium Q8BJD1 Inter-alpha-trypsin inhibitor heavy chain H5 OS=Mus musculus OX=10090 GN=Itih5 PE=1 SV=1 0.021 1.733 1 1 1 1 952 106.7 8.16 1 1 22002.94336 6463.178223 106362.4141 1 1 1 metabolic process;regulation of biological process extracellular enzyme regulator activity "Pf00092, Pf06668, Pf08487, Pf10138, Pf13519, Pf13768" 209378 ENSMUSG00000025780.7 Itih5 2 0 Low A0A1D5RM61 Ankyrin and armadillo repeat-containing protein OS=Mus musculus OX=10090 GN=Ankar PE=4 SV=1 0.083 1.056 2 1 1 1 1247 140.4 8.37 1 1 185784.1875 125724.3438 185593.5625 1 1 1 cytoplasm;membrane;nucleus protein binding "Pf00514, Pf12796, Pf13637, Pf13857" 319695 ENSMUSG00000039342.5 Ankar 1 0 High E9QMZ0 Cell death activator CIDE-3 OS=Mus musculus OX=10090 GN=Cidec PE=1 SV=1 0.002 4.276 8 1 1 1 249 28.5 9.51 1 1 cell death;cell organization and biogenesis;metabolic process;regulation of biological process cytosol;endoplasmic reticulum;nucleus Pf02017 14311 ENSMUSG00000030278.11 Cidec 6 0 Low A0A075B5V9 Immunoglobulin heavy variable 1-49 OS=Mus musculus OX=10090 GN=Ighv1-49 PE=4 SV=1 0.06 1.262 17 1 1 1 98 10.9 6.52 1 1 23863.89453 130972.3984 1 1 ENSMUSG00000076710.2 LOC634688 12 0 Medium Q91ZE0 "Trimethyllysine dioxygenase, mitochondrial OS=Mus musculus OX=10090 GN=Tmlhe PE=1 SV=2" 0.023 1.633 3 1 1 1 421 49.6 8.25 1 1 20329.39063 95425.07031 30601.75391 122766.6875 1 1 1 1 metabolic process;regulation of biological process mitochondrion;organelle lumen catalytic activity;metal ion binding "Pf02668, Pf06155" 192289 ENSMUSG00000079834.2 Tmlhe X Carnitine synthesis Lysine degradation 0 Medium Q8BUE4 Ferroptosis suppressor protein 1 OS=Mus musculus OX=10090 GN=Aifm2 PE=1 SV=1 0.02 1.689 3 1 1 1 373 40.6 8.98 1 1 159388.7031 1 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;cytosol;membrane;mitochondrion catalytic activity;DNA binding;nucleotide binding "Pf00070, Pf07992" 71361 ENSMUSG00000020085.15 Aifm2 10 0 Medium A0A494BAW3 Latent-transforming growth factor beta-binding protein 3 (Fragment) OS=Mus musculus OX=10090 GN=Ltbp3 PE=1 SV=1 0.039 1.425 14 1 1 1 118 12.5 8.21 1 1 56287.78516 1 0 High Q8CEE7 Retinol dehydrogenase 13 OS=Mus musculus OX=10090 GN=Rdh13 PE=1 SV=1 0.006 2.465 4 1 1 1 334 36.4 8.85 1 1 metabolic process;response to stimulus mitochondrion catalytic activity "Pf00106, Pf03435, Pf08659" 108841 ENSMUSG00000008435.15 Rdh13 7 RA biosynthesis pathway 0 High P99024 Tubulin beta-5 chain OS=Mus musculus OX=10090 GN=Tubb5 PE=1 SV=1 0 190.164 72 25 304 4 444 49.6 4.89 2 1 2 2 1 2 65061.16602 43624.51172 15104.11914 33965.72656 2 1 1 2 Met-loss [N-Term] cell organization and biogenesis cytoplasm;cytoskeleton;cytosol;membrane;nucleus catalytic activity;nucleotide binding;protein binding;structural molecule activity "Pf00091, Pf03953, Pf10644" 22154 ENSMUSG00000001525.10 Tubb5 17 Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Regulation of PLK1 Activity at G2/M Transition; Neutrophil degranulation; Recruitment of NuMA to mitotic centrosomes Phagosome; Gap junction 2 High P10126 Elongation factor 1-alpha 1 OS=Mus musculus OX=10090 GN=Eef1a1 PE=1 SV=3 0 129.744 64 21 270 21 462 50.1 9.01 3 1 2 3 2 2 1674713.597 1165128.417 356351.2847 1172801.185 14 9 6 12 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;nucleus catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00009, Pf03143, Pf03144" 13627 ENSMUSG00000037742.14 Eef1a1; LOC101056619 9 Legionellosis; RNA transport 0 High Q9CWF2 Tubulin beta-2B chain OS=Mus musculus OX=10090 GN=Tubb2b PE=1 SV=1 0 170.468 62 23 254 1 445 49.9 4.89 2 1 2 2 1 2 16203.8833 2 Met-loss [N-Term] cell organization and biogenesis;cellular component movement;regulation of biological process cytoplasm;cytoskeleton;nucleus catalytic activity;nucleotide binding;protein binding;structural molecule activity "Pf00091, Pf03953, Pf10644" 73710 ENSMUSG00000045136.5 Tubb2b 13 Intraflagellar transport; Hedgehog 'on' state; Hedgehog 'off' state Phagosome; Gap junction 0 High Q7TMM9 Tubulin beta-2A chain OS=Mus musculus OX=10090 GN=Tubb2a PE=1 SV=1 0 166.687 62 23 253 1 445 49.9 4.89 2 1 2 2 1 2 190051.6641 50711.79688 97988.35938 2 1 1 Met-loss [N-Term] cell organization and biogenesis cytoplasm;cytoskeleton;nucleus catalytic activity;nucleotide binding;structural molecule activity "Pf00091, Pf03953, Pf10644" 22151 ENSMUSG00000058672.6 Tubb2a 13 Intraflagellar transport; Hedgehog 'on' state; Hedgehog 'off' state Phagosome; Gap junction 2 High P07724 Serum albumin OS=Mus musculus OX=10090 GN=Alb PE=1 SV=3 0 168.678 58 31 216 31 608 68.6 6.07 13 13 3 2 22 20 3 2 9000714.428 10781936.68 3436789.025 1910232.58 29 24 23 23 cell communication;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;extracellular;Golgi;nucleus DNA binding;metal ion binding;protein binding Pf00273 11657 ENSMUSG00000029368.10 Alb 5 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Recycling of bile acids and salts; Platelet degranulation ; Transport of organic anions; HDL remodeling; Scavenging of heme from plasma Thyroid hormone synthesis 0 High Q99JC1 Ig lambda-2 chain C region (Fragment) OS=Mus musculus OX=10090 GN=Iglc2 PE=1 SV=1 0 94.945 85 5 201 5 105 11.3 6.27 5 5 1 2 36 28 1 2 28503106.16 21265514.13 1269057.648 886211.5586 8 7 4 6 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding "Pf07654, Pf08205, Pf13927" 110786 ENSMUSG00000076937.3 Iglc2 16 0 High P56480 "ATP synthase subunit beta, mitochondrial OS=Mus musculus OX=10090 GN=Atp5f1b PE=1 SV=2" 0 129.734 71 24 154 24 529 56.3 5.34 2 2 2090798.811 1979373.097 674814.5192 1874939.401 14 11 7 21 cell differentiation;cellular homeostasis;metabolic process;regulation of biological process;transport cell surface;membrane;mitochondrion;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding;receptor activity;transporter activity "Pf00006, Pf00306, Pf02874" 11947 ENSMUSG00000025393.12 Atp5b 10 Cristae formation; Formation of ATP by chemiosmotic coupling Metabolic pathways; Huntington's disease; Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High P63038 "60 kDa heat shock protein, mitochondrial OS=Mus musculus OX=10090 GN=Hspd1 PE=1 SV=1" 0 117.533 50 24 115 24 573 60.9 6.18 3 3 2 3 4 2 1861148.433 2307584.865 793356.2744 1648216.777 20 20 13 19 cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;cytosol;endoplasmic reticulum;endosome;Golgi;membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding;protein binding;RNA binding Pf00118 15510 ENSMUSG00000025980.14 Hspd1 1 RNA degradation; Tuberculosis; Legionellosis; Type I diabetes mellitus 0 High Q9ET01 "Glycogen phosphorylase, liver form OS=Mus musculus OX=10090 GN=Pygl PE=1 SV=4" 0 95.243 47 29 103 24 850 97.4 7.09 12 4 1 2 18 7 1 2 5913944.158 3806565.444 1522007.797 1274374.288 27 23 13 22 Met-loss+Acetyl [N-Term] cell death;metabolic process cytoplasm catalytic activity;nucleotide binding;protein binding Pf00343 110095 ENSMUSG00000021069.16 Pygl 12 Glycogen breakdown (glycogenolysis); Neutrophil degranulation Insulin signaling pathway; Metabolic pathways; Insulin resistance; Starch and sucrose metabolism; Glucagon signaling pathway 5 High P05784 "Keratin, type I cytoskeletal 18 OS=Mus musculus OX=10090 GN=Krt18 PE=1 SV=5" 0 92.747 57 20 97 18 423 47.5 5.33 2 1 2 1 4 1 2 2 1496545.879 16420133.75 951676.8389 2047145.503 6 2 3 4 cell death;cell organization and biogenesis;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;nucleus protein binding;RNA binding;structural molecule activity Pf00038 16668 ENSMUSG00000023043.6 Krt18 15 Formation of the cornified envelope 2 High A0A075B5N4 Immunoglobulin kappa chain variable 8-27 OS=Mus musculus OX=10090 GN=Igkv8-27 PE=4 SV=1 0 38.623 49 4 71 1 100 11 7.96 4 3 1 1 14 7 1 2 5199221.063 1126029.686 2 2 Pf07686 ENSMUSG00000076580.3 6 0 High P01592 Immunoglobulin J chain OS=Mus musculus OX=10090 GN=Jchain PE=1 SV=4 0 37.69 36 6 67 6 159 18 4.89 3 2 1 5 5 2 2390771.947 3430913.042 483430.3223 896463.335 6 4 5 6 defense response;regulation of biological process;response to stimulus extracellular DNA binding;protein binding Pf15097 16069 ENSMUSG00000067149.6 Igj; Jchain 5 Cell surface interactions at the vascular wall; Scavenging of heme from plasma 0 High Q9Z2K1 "Keratin, type I cytoskeletal 16 OS=Mus musculus OX=10090 GN=Krt16 PE=1 SV=3" 0 40.139 20 11 60 6 469 51.6 5.2 1 3 1 1 2 3 1 2 79762.91016 657956.5313 11294.67969 46968.71484 3 2 1 2 cell differentiation;cell organization and biogenesis;cellular component movement;defense response;regulation of biological process;response to stimulus cytoskeleton;nucleus protein binding;structural molecule activity "Pf00038, Pf13514" 16666 ENSMUSG00000053797.10 Krt16 11 Formation of the cornified envelope 2 High A0A140T8M3 Immunoglobulin kappa chain variable 8-30 (Fragment) OS=Mus musculus OX=10090 GN=Igkv8-30 PE=4 SV=2 0 32.79 50 5 58 2 121 13.3 6.49 5 2 1 1 13 5 1 2 3392803.984 79636.03125 45084.5625 3 1 1 Pf07686 384419 ENSMUSG00000076577.2 Igkv8-30 6 0 High P01029 Complement C4-B OS=Mus musculus OX=10090 GN=C4b PE=1 SV=3 0 86.986 22 21 56 21 1738 192.8 7.53 1 1 1 2 1 1 1 2 2913775.125 2451546.652 1537853.272 1753832.201 13 13 9 12 defense response;metabolic process;regulation of biological process;response to stimulus extracellular enzyme regulator activity;protein binding "Pf00207, Pf01759, Pf01821, Pf01835, Pf07677, Pf07678, Pf07703, Pf10569, Pf11974, Pf13249" 12268 ENSMUSG00000073418.4 C4b 17 Regulation of Complement cascade; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Activation of C3 and C5; Post-translational protein phosphorylation; Initial triggering of complement Staphylococcus aureus infection; Complement and coagulation cascades; Pertussis; Systemic lupus erythematosus 0 High A0A140T8P7 Immunoglobulin kappa variable 8-21 (Fragment) OS=Mus musculus OX=10090 GN=Igkv8-21 PE=1 SV=2 0 38.612 34 5 55 2 120 13.1 8.28 3 3 1 1 7 6 1 2 10703731.68 8609230.87 1338690.234 916006.6221 6 7 4 5 Pf07686 620400 ENSMUSG00000076586.2 Igkv8-21 6 4 High E9Q0F0 Keratin 78 OS=Mus musculus OX=10090 GN=Krt78 PE=1 SV=1 0 12.928 2 2 54 1 1068 112.2 7.97 1 1 1 1 4 2 2648691 9068479.57 1098827.5 1372095.711 2 2 1 2 cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;transport cytoskeleton;Golgi;membrane catalytic activity;motor activity;protein binding;structural molecule activity;transporter activity "Pf00038, Pf01576, Pf02050, Pf02321, Pf02403, Pf03280, Pf03938, Pf04111, Pf04156, Pf04740, Pf04977, Pf05008, Pf05103, Pf05335, Pf05483, Pf05557, Pf05622, Pf05642, Pf05667, Pf05911, Pf06013, Pf06133, Pf06160, Pf06810, Pf07321, Pf07926, Pf08614, Pf09606, Pf09726, Pf09731, Pf09755, Pf11559, Pf11932, Pf12128, Pf12325, Pf12329, Pf12795, Pf13514, Pf13851, Pf14362, Pf15070, Pf15397" 332131 ENSMUSG00000050463.8 Krt78 15 Formation of the cornified envelope 0 High A0A075B5Q3 Immunoglobulin heavy variable 2-5 OS=Mus musculus OX=10090 GN=Ighv2-5 PE=4 SV=1 0 27.718 34 3 52 3 115 12.5 8.97 3 3 2 5 9 2 3234505.184 8275412.8 199357.0078 469852.4873 6 6 2 3 ENSMUSG00000096498.3 12 0 High Q9DCW4 Electron transfer flavoprotein subunit beta OS=Mus musculus OX=10090 GN=Etfb PE=1 SV=3 0 42.815 44 9 52 9 255 27.6 8.1 4 3 2 7 5 2 1745948.117 2485130.551 596170.7988 1014217.99 9 9 8 9 metabolic process;transport cytosol;mitochondrion;organelle lumen Pf01012 110826 ENSMUSG00000004610.4 Etfb 7 Protein methylation; Respiratory electron transport 0 High P98086 Complement C1q subcomponent subunit A OS=Mus musculus OX=10090 GN=C1qa PE=1 SV=2 0 28.488 29 5 52 5 245 26 9.11 2 2 2 5 3 2 5646773.02 3092581.133 996714.4531 2076673.742 6 4 2 4 defense response;metabolic process;regulation of biological process;response to stimulus extracellular;membrane protein binding "Pf00229, Pf00386" 12259 ENSMUSG00000036887.5 C1qa 4 Regulation of Complement cascade; Classical antibody-mediated complement activation Chagas disease (American trypanosomiasis); Staphylococcus aureus infection; Complement and coagulation cascades; Pertussis; Prion diseases; Systemic lupus erythematosus 0 High A0A140T8M4 Immunoglobulin kappa variable 8-19 OS=Mus musculus OX=10090 GN=Igkv8-19 PE=1 SV=2 0 20.614 60 5 51 2 101 11.1 5.25 4 1 1 9 3 2 1108820.02 286610.8711 108446.917 3 3 2 "Pf07679, Pf07686, Pf13927" ENSMUSG00000096594.2 6 0 High A0A0G2JE99 Immunoglobulin lambda constant 1 (Fragment) OS=Mus musculus OX=10090 GN=Iglc1 PE=4 SV=1 0 33.721 80 5 49 5 106 11.7 6.27 3 2 1 1 13 3 1 2 10810218.33 6205567.391 584551.4375 874989.561 5 3 1 4 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding "Pf07654, Pf13927" ENSMUSG00000105906.1 16 Cell surface interactions at the vascular wall 0 High A0A0B4J1H7 Immunoglobulin kappa variable 1-135 (Fragment) OS=Mus musculus OX=10090 GN=Igkv1-135 PE=4 SV=1 0 33.771 46 7 49 7 120 13.3 7.12 5 1 1 2 8 3 1 2 7110574.82 2462019.951 1095971.047 1201487.445 7 5 4 4 response to stimulus 243420 ENSMUSG00000096336.2 Igkv1-135 6 0 High Q8BGZ7 "Keratin, type II cytoskeletal 75 OS=Mus musculus OX=10090 GN=Krt75 PE=1 SV=1" 0 32.52 18 13 49 1 551 59.7 8.31 2 2 1 2 2 3 1 2 110929.0625 35717.92188 2 1 cell differentiation;metabolic process;transport catalytic activity;motor activity;protein binding;structural molecule activity;transporter activity "Pf00012, Pf00038, Pf01496, Pf01576, Pf04111, Pf04156, Pf09728, Pf13166" 109052 ENSMUSG00000022986.5 Krt75 15 Formation of the cornified envelope 1 High P01631 Ig kappa chain V-II region 26-10 OS=Mus musculus OX=10090 PE=1 SV=1 0 21.143 39 3 49 1 113 12.3 8.88 3 3 1 2 8 8 1 2 1909143.563 1301986.828 1338022.383 362124.0703 1 1 1 1 metal ion binding Pf07686 16098 Igkv1-117 6 0 High A0A075B5V6 Immunoglobulin heavy variable V1-42 OS=Mus musculus OX=10090 GN=Ighv1-42 PE=1 SV=1 0 30.838 80 5 45 3 98 10.8 8.73 4 2 1 9 2 2 5324775.75 34129.80078 446805.0625 3 1 3 Pf07686 ENSMUSG00000094652.2 12 0 High Q3UV17 "Keratin, type II cytoskeletal 2 oral OS=Mus musculus OX=10090 GN=Krt76 PE=1 SV=1" 0 22.226 10 9 42 1 594 62.8 8.43 2 2 2 2 2 2 462660.4688 774292.4375 467438.6563 1 1 1 nucleus catalytic activity;motor activity;protein binding;structural molecule activity "Pf00038, Pf01576, Pf10473" 77055 ENSMUSG00000075402.1 Krt76 15 Formation of the cornified envelope 0 High P01635 Ig kappa chain V-V region K2 (Fragment) OS=Mus musculus OX=10090 PE=1 SV=1 0 17.623 33 3 40 1 115 12.6 8.31 2 2 2 2 6 5 2 2 5477391.211 4986928.068 879057.043 1154884.096 2 2 2 2 "Pf00047, Pf07679, Pf07686, Pf13927" 619960 ENSMUSG00000095007.1 Igkv12-41 6 1 High A0A075B5M4 Immunoglobulin kappa variable 4-57-1 (Fragment) OS=Mus musculus OX=10090 GN=Igkv4-57-1 PE=4 SV=1 0 19.043 27 2 39 1 119 12.7 7.11 1 1 1 1 4 2 2 2 426827.7119 238400.5078 22544.79883 188234.3438 1 1 1 1 response to stimulus Pf07686 ENSMUSG00000076555.3 LOC675950 6 0 High Q8JZR0 Long-chain-fatty-acid--CoA ligase 5 OS=Mus musculus OX=10090 GN=Acsl5 PE=1 SV=1 0 57.334 40 18 36 16 683 76.2 7.09 1 1 1 2 96479.19434 65633.37427 643542.0708 4 2 8 metabolic process;regulation of biological process;transport endoplasmic reticulum;membrane;mitochondrion;nucleus catalytic activity;nucleotide binding Pf00501 433256 ENSMUSG00000024981.5 Acsl5 19 Synthesis of very long-chain fatty acyl-CoAs PPAR signaling pathway; Fatty acid metabolism; Metabolic pathways; Fatty acid degradation; Adipocytokine signaling pathway; Fatty acid biosynthesis; Peroxisome 2 High Q61765 "Keratin, type I cuticular Ha1 OS=Mus musculus OX=10090 GN=Krt31 PE=1 SV=2" 0 16.381 15 6 35 1 416 47.1 4.89 1 2 1 1 2 2 1 2 211977.9258 31882.17285 3 2 catalytic activity;motor activity;structural molecule activity "Pf00038, Pf01576, Pf13514" 16660 ENSMUSG00000048981.1 Krt31 11 Formation of the cornified envelope 4 High Q8VEM8 "Phosphate carrier protein, mitochondrial OS=Mus musculus OX=10090 GN=Slc25a3 PE=1 SV=1" 0 26.494 30 8 34 8 357 39.6 9.26 2 2 238820.8926 601561.7656 120005.9531 959168.9688 4 4 2 6 transport membrane;mitochondrion protein binding;transporter activity Pf00153 18674 ENSMUSG00000061904.12 Slc25a3 10 0 High A0A0B4J1I3 Immunoglobulin kappa variable 4-74 (Fragment) OS=Mus musculus OX=10090 GN=Igkv4-74 PE=4 SV=1 0 15.414 37 2 34 1 119 12.9 8.02 1 1 1 1 4 2 2 2 69476.4375 80675.10938 1 1 response to stimulus Pf07686 236047 ENSMUSG00000076543.2 Igkv4-74 6 0 High P17751 Triosephosphate isomerase OS=Mus musculus OX=10090 GN=Tpi1 PE=1 SV=4 0 32.411 36 8 33 8 299 32.2 5.74 2 2 2 2 2 2 1077204.539 1051340.293 169395.5938 273558.1328 7 6 2 5 development;metabolic process cytosol;nucleus catalytic activity;protein binding Pf00121 21991 ENSMUSG00000023456.14 Tpi1 6 Gluconeogenesis; Glycolysis Metabolic pathways; Biosynthesis of amino acids; Glycolysis / Gluconeogenesis; Inositol phosphate metabolism; Carbon metabolism; Fructose and mannose metabolism 0 High A0A0B4J1J1 Immunoglobulin kappa chain variable 5-45 (Fragment) OS=Mus musculus OX=10090 GN=Igkv5-45 PE=4 SV=1 0 12.681 23 2 33 1 115 12.7 7.28 1 2 1 4 7 2 1161991.75 400492.625 662719.8125 1 1 1 response to stimulus "Pf00047, Pf07679, Pf07686, Pf13927" 545850 ENSMUSG00000094094.2 Igkv5-45 6 0 High A0A140T8P6 Immunoglobulin kappa variable 12-46 (Fragment) OS=Mus musculus OX=10090 GN=Igkv12-46 PE=1 SV=2 0 22.884 41 3 32 2 115 12.6 5.91 3 1 1 2 6 2 1 2 4469153.656 1601506.938 350916.4844 505007.4688 2 2 1 2 protein binding "Pf00047, Pf07679, Pf07686, Pf13895" 692245 ENSMUSG00000076564.2 Igkv12-46 6 0 High P01638 Ig kappa chain V-V region L6 (Fragment) OS=Mus musculus OX=10090 PE=4 SV=1 0 20.277 36 3 31 3 115 13 7.81 3 1 1 8 2 2 3669780.429 1231098.377 304957.0156 578927.5654 4 3 2 4 "Pf00047, Pf07679, Pf07686" 16129; 545847 Igk-V9; Igkv14-111 6 0 High P01648 Ig kappa chain V-V region HP 91A3 OS=Mus musculus OX=10090 PE=1 SV=1 0 12.662 42 4 29 1 108 12 8.47 2 1 1 5 2 2 "Pf00047, Pf07679, Pf07686" 0 High A0A075B5M1 Immunoglobulin kappa variable 4-63 OS=Mus musculus OX=10090 GN=Igkv4-63 PE=1 SV=1 0 23.204 57 4 29 3 95 10.2 5.87 2 1 1 4 1 2 823378.1963 559710.1973 121836.1211 322346.4766 4 3 2 3 "Pf00047, Pf07679, Pf07686" ENSMUSG00000076550.3 6 0 High A0A075B5R0 Immunoglobulin heavy variable 5-16 OS=Mus musculus OX=10090 GN=Ighv5-16 PE=1 SV=1 0 15.605 33 3 29 3 116 13.2 7.81 2 2 1 7 2 2 8270190.961 1589888.555 244208.1367 826242.4609 4 2 1 2 Pf07686 ENSMUSG00000094194.2 12 0 High A1L317 "Keratin, type I cytoskeletal 24 OS=Mus musculus OX=10090 GN=Krt24 PE=2 SV=2" 0.002 3.905 3 2 28 1 512 54 5.01 1 1 1 1 2 1 1 2 structural molecule activity Pf00038 75706 ENSMUSG00000020913.3 Krt24 11 Formation of the cornified envelope 0 High A0A075B5M3 Immunoglobulin kappa variable 4-58 OS=Mus musculus OX=10090 GN=Igkv4-58 PE=1 SV=1 0 17.744 64 4 27 3 97 10.3 7.28 2 1 1 5 2 2 5815486.484 681081.6563 269485.9688 428714.9844 5 2 1 2 Pf07686 ENSMUSG00000095633.2 6 1 High A0A075B5L2 Immunoglobulin kappa chain variable 4-91 (Fragment) OS=Mus musculus OX=10090 GN=Igkv4-91 PE=4 SV=2 0 20.156 33 2 24 1 119 12.7 7.12 2 1 1 9 2 2 3965997.125 1 response to stimulus Pf07686 434033 ENSMUSG00000076532.3 Igkv4-91 6 0 Medium Q6P5H2 Nestin OS=Mus musculus OX=10090 GN=Nes PE=1 SV=1 0.02 1.702 0 1 23 1 1864 207 4.34 1 1 1 1 2 2 3395509.5 17980612 1609982.375 1 1 1 cell organization and biogenesis;cell proliferation;development;regulation of biological process cytoplasm;cytoskeleton protein binding;structural molecule activity "Pf00038, Pf02463" 18008 ENSMUSG00000004891.16 Nes 3 0 High P18242 Cathepsin D OS=Mus musculus OX=10090 GN=Ctsd PE=1 SV=1 0 19.108 19 6 21 6 410 44.9 7.15 1 2 49252.14648 32649.60303 1080673.766 2 3 6 cell organization and biogenesis;metabolic process extracellular;membrane;mitochondrion;vacuole catalytic activity "Pf00026, Pf07966, Pf14541, Pf14543" 13033 ENSMUSG00000007891.16 Ctsd 7 MHC class II antigen presentation; Neutrophil degranulation; Collagen degradation Tuberculosis; Lysosome; Sphingolipid signaling pathway; Apoptosis 0 High Q9CZU6 "Citrate synthase, mitochondrial OS=Mus musculus OX=10090 GN=Cs PE=1 SV=1" 0 18.46 20 7 21 7 464 51.7 8.57 3 1 1 2 3 1 1 2 1011691.297 1573876.691 691560.1406 854945.0938 5 6 4 4 metabolic process mitochondrion;nucleus;organelle lumen catalytic activity;RNA binding Pf00285 12974 ENSMUSG00000005683.8 Cs 10 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Biosynthesis of amino acids; 2-Oxocarboxylic acid metabolism; Carbon metabolism; Glyoxylate and dicarboxylate metabolism 0 High P61982 14-3-3 protein gamma OS=Mus musculus OX=10090 GN=Ywhag PE=1 SV=2 0 19.133 31 6 20 3 247 28.3 4.89 1 2 2 1 3 2 184493.6035 782600.9258 83321.37988 165862.7813 3 2 2 2 metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;membrane catalytic activity;protein binding;RNA binding Pf00244 22628 ENSMUSG00000051391.9 Ywhag 5 Translocation of GLUT4 to the plasma membrane; Anchoring of the basal body to the plasma membrane; Activation of BAD and translocation to mitochondria ; AURKA Activation by TPX2; RHO GTPases activate PKNs; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex Epstein-Barr virus infection; Hippo signaling pathway; Oocyte meiosis; Cell cycle; PI3K-Akt signaling pathway; Viral carcinogenesis 0 High O54734 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Mus musculus OX=10090 GN=Ddost PE=1 SV=2 0 20.081 25 7 19 7 441 49 5.83 2 2 914630.0977 747687.5117 319448.8789 560883.3145 2 2 2 6 metabolic process;response to stimulus endoplasmic reticulum;membrane catalytic activity Pf03345 13200 ENSMUSG00000028757.4 Ddost 4 Neutrophil degranulation Metabolic pathways; N-Glycan biosynthesis; Protein processing in endoplasmic reticulum 0 High K4DI77 WD repeat-containing protein 81 (Fragment) OS=Mus musculus OX=10090 GN=Wdr81 PE=1 SV=1 0 16.076 6 8 18 8 1934 211.8 5.77 2 1 2 3 1 2 415167.8384 1046553.094 385199.9258 617360.0625 3 4 4 4 cell organization and biogenesis mitochondrion protein binding "Pf00400, Pf02138" ENSMUSG00000045374.18 11 0 High P04117 "Fatty acid-binding protein, adipocyte OS=Mus musculus OX=10090 GN=Fabp4 PE=1 SV=3" 0 17.152 36 6 17 6 132 14.6 8.4 6 4 2 10 5 2 3433648.344 2024636.867 1088153.797 670893.5156 6 6 4 6 cell differentiation;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;nucleus transporter activity Pf00061 11770 ENSMUSG00000062515.3 Fabp4 3 Triglyceride catabolism; Mus musculus biological processes; Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes PPAR signaling pathway; Regulation of lipolysis in adipocytes 0 High P46978 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Mus musculus OX=10090 GN=Stt3a PE=1 SV=1 0 17.161 13 9 14 8 705 80.5 8.1 2 2 7842.30957 582438.5859 1 6 metabolic process endoplasmic reticulum;membrane catalytic activity;metal ion binding Pf02516 16430 ENSMUSG00000032116.18 Stt3a 9 Metabolic pathways; N-Glycan biosynthesis; Protein processing in endoplasmic reticulum 1 High A0A075B684 Immunoglobulin heavy variable 1-62-1 OS=Mus musculus OX=10090 GN=Ighv1-62-1 PE=4 SV=1 0 16.672 63 1 14 1 30 3.2 9.04 1 1 1 3 1 2 5132498.125 1982811.625 1598573.031 1 1 1 ENSMUSG00000102313.1 12 0 High A0A140T8P3 Immunoglobulin kappa chain variable 15-103 (Fragment) OS=Mus musculus OX=10090 GN=Igkv15-103 PE=4 SV=2 0 9.674 10 1 13 1 115 12.5 7.8 1 1 1 2 2 2 2037784 578855.0313 588627.5469 410145.2656 1 1 1 1 Pf07686 692169 ENSMUSG00000076523.2 Igkv15-103 6 0 High B8JJX7 Survival motor neuron protein (Fragment) OS=Mus musculus OX=10090 GN=Smn1 PE=1 SV=8 0 9.124 25 2 13 2 161 17.5 5.27 1 1 2 2 536864.9141 237579.0469 237124.8574 2 1 2 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;nucleus RNA binding "Pf00567, Pf06003" ENSMUSG00000021645.16 13 0 High Q9CQX8 "28S ribosomal protein S36, mitochondrial OS=Mus musculus OX=10090 GN=Mrps36 PE=1 SV=1" 0 14.835 57 3 13 3 102 11.1 9.99 2 2 2 1 6 3 2 2 3010624.25 2172563.344 1261509.461 1235466.531 3 3 2 3 mitochondrion;ribosome Pf10937 66128 ENSMUSG00000061474.11 Mrps36 13 Mitochondrial translation termination; Mitochondrial translation elongation 0 High A0A1L1STE6 "Isocitrate dehydrogenase [NAD] subunit, mitochondrial OS=Mus musculus OX=10090 GN=Idh3a PE=1 SV=1" 0 13.082 16 5 12 5 384 41.5 6.93 5 2 1 1 6 3 1 2 2005602.84 770427.3398 381750.3496 548873.438 5 2 2 4 metabolic process mitochondrion catalytic activity;metal ion binding;nucleotide binding Pf00180 ENSMUSG00000032279.11 9 0 High Q61646 Haptoglobin OS=Mus musculus OX=10090 GN=Hp PE=1 SV=1 0 9.379 11 4 11 4 347 38.7 6.29 2 2 106801.0078 69319.83105 241424.9453 4 3 4 defense response;metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;extracellular;Golgi antioxidant activity;catalytic activity;protein binding "Pf00084, Pf00089" 15439 ENSMUSG00000031722.10 Hp 8 Neutrophil degranulation; Scavenging of heme from plasma 0 High Q9CR62 Mitochondrial 2-oxoglutarate/malate carrier protein OS=Mus musculus OX=10090 GN=Slc25a11 PE=1 SV=3 0 6.614 8 2 9 2 314 34.1 9.94 2 2 216694.4805 93694.00586 60385.94141 420361.3281 2 2 2 2 transport membrane;mitochondrion;nucleus RNA binding;transporter activity Pf00153 67863 ENSMUSG00000014606.14 Slc25a11 11 Gluconeogenesis 0 High Q9CPQ1 Cytochrome c oxidase subunit 6C OS=Mus musculus OX=10090 GN=Cox6c PE=1 SV=3 0.004 2.641 17 1 6 1 76 8.5 10.14 1 1 3 2 85303.07813 836938.9189 172508.3223 187577.9531 1 1 1 1 Met-loss+Acetyl [N-Term] metabolic process;transport membrane;mitochondrion catalytic activity;transporter activity Pf02937 12864 ENSMUSG00000014313.14 Cox6c 15 Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 High E9Q1J7 "Propionyl-CoA carboxylase beta chain, mitochondrial OS=Mus musculus OX=10090 GN=Pccb PE=1 SV=1" 0 7.088 10 3 6 3 504 54.6 7.49 1 2 2 1 2 2 295744.5078 308700.625 359405.9297 368455.2578 2 2 2 2 metabolic process mitochondrion catalytic activity;nucleotide binding Pf01039 66904 ENSMUSG00000032527.13 Pccb 9 0 High Q8R0Y8 Mitochondrial coenzyme A transporter SLC25A42 OS=Mus musculus OX=10090 GN=Slc25a42 PE=1 SV=1 0 6.209 15 3 5 3 318 35.2 10.05 1 2 1 2 209552.7578 3254970.688 1498182.844 1984401.734 2 3 3 3 transport membrane;mitochondrion;nucleus catalytic activity;transporter activity Pf00153 73095 ENSMUSG00000002346.16 Slc25a42 8 0 High P46412 Glutathione peroxidase 3 OS=Mus musculus OX=10090 GN=Gpx3 PE=1 SV=2 0 5.331 13 3 4 3 226 25.4 8.22 2 2 11398.89355 100921.1563 294372.2891 1 1 3 cell organization and biogenesis;metabolic process;response to stimulus extracellular antioxidant activity;catalytic activity Pf00255 14778 ENSMUSG00000018339.11 Gpx3 11 Detoxification of Reactive Oxygen Species Glutathione metabolism; Thyroid hormone synthesis; Arachidonic acid metabolism 0 High Q9CQZ5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Mus musculus OX=10090 GN=Ndufa6 PE=1 SV=1 0.002 5.016 13 1 3 1 131 15.3 10.11 1 1 1 2 77274.77344 223688.6406 187774.7813 840660.9375 1 1 1 1 metabolic process;response to stimulus;transport membrane;mitochondrion "Pf05347, Pf13232, Pf13233" 67130 ENSMUSG00000022450.5 Ndufa6 15 Complex I biogenesis Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High Q8VIB3 "Type 2 lactosamine alpha-2,3-sialyltransferase OS=Mus musculus OX=10090 GN=St3gal6 PE=2 SV=3" 0.004 2.777 8 2 2 2 329 37.8 9.16 2 2 389802.9688 207295.4297 1 2 metabolic process;response to stimulus Golgi;membrane catalytic activity Pf00777 54613 ENSMUSG00000022747.16 St3gal6 16 Keratan sulfate biosynthesis; Sialic acid metabolism Metabolic pathways; Glycosphingolipid biosynthesis - lacto and neolacto series 0 High O70423 Membrane primary amine oxidase OS=Mus musculus OX=10090 GN=Aoc3 PE=1 SV=3 0.002 4.391 5 2 2 2 765 84.5 6.42 2 2 171803.7969 1 cellular component movement;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;endoplasmic reticulum;endosome;Golgi;membrane catalytic activity;metal ion binding;protein binding "Pf01179, Pf02727, Pf02728" 11754 ENSMUSG00000019326.14 Aoc3 11 Phase I - Functionalization of compounds "Metabolic pathways; Glycine, serine and threonine metabolism; beta-Alanine metabolism; Phenylalanine metabolism; Tyrosine metabolism" 0 High P68372 Tubulin beta-4B chain OS=Mus musculus OX=10090 GN=Tubb4b PE=1 SV=1 0 199.497 71 25 320 1 445 49.8 4.89 3 1 3 3 1 3 1977678.524 1569717.984 1166736.403 2322344.412 13 8 7 19 Met-loss [N-Term] cell organization and biogenesis cytoplasm;cytoskeleton;nucleus catalytic activity;nucleotide binding;RNA binding;structural molecule activity "Pf00091, Pf03953, Pf10644" 227613 ENSMUSG00000036752.4 Tubb4b 2 Anchoring of the basal body to the plasma membrane; Intraflagellar transport; Hedgehog 'on' state; AURKA Activation by TPX2; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Hedgehog 'off' state; Regulation of PLK1 Activity at G2/M Transition; Neutrophil degranulation; Recruitment of NuMA to mitotic centrosomes Phagosome; Gap junction 30 High Q8VCM7 Fibrinogen gamma chain OS=Mus musculus OX=10090 GN=Fgg PE=1 SV=1 0 177.294 60 23 180 23 436 49.4 5.86 13 4 1 2 22 6 1 3 12285475.93 3809009.492 601571.7275 2097372.729 23 14 6 15 cell organization and biogenesis;coagulation;defense response;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;extracellular metal ion binding;protein binding;structural molecule activity "Pf00147, Pf08702" 99571 ENSMUSG00000033860.13 Fgg 3 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); p130Cas linkage to MAPK signaling for integrins; Post-translational protein phosphorylation; Integrin cell surface interactions; Regulation of TLR by endogenous ligand; Common Pathway of Fibrin Clot Formation; GRB2:SOS provides linkage to MAPK signaling for Integrins ; Platelet degranulation Staphylococcus aureus infection; Platelet activation; Complement and coagulation cascades 0 High A0A0A6YXW6 Immunoglobulin heavy constant alpha (Fragment) OS=Mus musculus OX=10090 GN=Igha PE=1 SV=1 0 136.51 49 12 159 12 389 42 4.94 5 3 2 2 7 3 2 3 4067363.753 2400747.914 2100789.188 1993126.568 12 9 9 10 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07654 ENSMUSG00000095079.6 12 Cell surface interactions at the vascular wall; Scavenging of heme from plasma 0 High P01869 "Ig gamma-1 chain C region, membrane-bound form OS=Mus musculus OX=10090 GN=Ighg1 PE=1 SV=2" 0 80.316 27 8 143 1 393 43.4 6.44 6 2 2 25 2 3 10568591.25 2339968.719 1659502.914 826525.1875 2 2 2 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus membrane protein binding "Pf07654, Pf08205" 16017 Ighg1 12 0 High Q91VB8 Alpha globin 1 OS=Mus musculus OX=10090 GN=Hba-a1 PE=1 SV=1 0 88.316 92 10 112 10 142 15.1 8.22 8 6 1 3 21 11 1 3 12329496.23 10532496.79 2518956.969 2260126.182 11 9 6 8 Met-loss [N-Term] response to stimulus;transport membrane antioxidant activity;catalytic activity;metal ion binding;protein binding;transporter activity Pf00042 15122; 110257 ENSMUSG00000069919.7; ENSMUSG00000069917.7 Hba-a1; Hba-a2 11 Erythrocytes take up carbon dioxide and release oxygen; Erythrocytes take up oxygen and release carbon dioxide; Scavenging of heme from plasma African trypanosomiasis; Malaria 0 High Q3TTY5 "Keratin, type II cytoskeletal 2 epidermal OS=Mus musculus OX=10090 GN=Krt2 PE=1 SV=1" 0 26.481 8 8 80 5 707 70.9 8.06 4 2 2 5 3 3 2277065.444 6694322.936 239322.3096 730523.7075 7 6 2 5 cell organization and biogenesis;cell proliferation;cellular component movement;metabolic process cytoskeleton;membrane;nucleus protein binding;structural molecule activity "Pf00038, Pf13166" 16681 ENSMUSG00000064201.8 Krt2 15 Formation of the cornified envelope 0 High A0A0B4J1J2 Immunoglobulin kappa chain variable 5-43 (Fragment) OS=Mus musculus OX=10090 GN=Igkv5-43 PE=1 SV=1 0 33.58 23 2 70 1 115 12.6 6.51 2 2 2 9 11 3 8332138.234 32242934.56 649033.75 318064.0625 2 2 1 1 response to stimulus "Pf00047, Pf07679, Pf07686, Pf13927" 381783 ENSMUSG00000094433.2 Igkv5-43 6 0 High P50446 "Keratin, type II cytoskeletal 6A OS=Mus musculus OX=10090 GN=Krt6a PE=1 SV=3" 0 65.927 26 19 70 6 553 59.3 7.94 2 3 1 3 2 4 1 3 2103687.118 4332096.29 2418176.69 2224471.974 7 10 5 11 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus catalytic activity;motor activity;structural molecule activity "Pf00038, Pf01576, Pf04111, Pf05957, Pf12128, Pf13166" 16687 ENSMUSG00000058354.6 Krt6a 15 Formation of the cornified envelope 11 High P62702 "40S ribosomal protein S4, X isoform OS=Mus musculus OX=10090 GN=Rps4x PE=1 SV=2" 0 33.272 38 9 65 9 263 29.6 10.15 1 1 3 1 1 3 524766.1709 479179.0112 380075.3203 308745.1299 6 5 4 4 development;metabolic process;regulation of biological process cytoplasm;membrane;nucleus;ribosome RNA binding;structural molecule activity "Pf00900, Pf08071" 20102 ENSMUSG00000031320.9 Rps4x X "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High P01654 Ig kappa chain V-III region PC 2880/PC 1229 OS=Mus musculus OX=10090 PE=1 SV=1 0 28.002 91 5 57 2 111 12 5.34 4 1 2 2 16 3 2 3 6353049.581 969303.0039 661989.2969 261741.981 3 2 2 1 cell differentiation;cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus membrane protein binding Pf07686 2 High Q922U2 "Keratin, type II cytoskeletal 5 OS=Mus musculus OX=10090 GN=Krt5 PE=1 SV=1" 0 39.723 18 14 56 6 580 61.7 7.75 2 2 1 3 2 3 1 3 476538.3379 1406669.653 540353.9063 1146135.597 4 4 3 3 metabolic process cytoplasm;membrane;mitochondrion;nucleus catalytic activity;motor activity;protein binding;structural molecule activity "Pf00038, Pf01576, Pf03961, Pf04111, Pf05957" 110308 ENSMUSG00000061527.6 Krt5 15 Type I hemidesmosome assembly; Formation of the cornified envelope 0 High P03977 Ig kappa chain V-III region 50S10.1 OS=Mus musculus OX=10090 PE=1 SV=1 0 22.877 68 4 53 1 111 12 5.06 4 1 2 2 16 3 2 3 176081.9375 1 Pf07686 0 High A0A140T8Q3 Immunoglobulin kappa variable 6-17 (Fragment) OS=Mus musculus OX=10090 GN=Igkv6-17 PE=1 SV=2 0 30.369 40 4 50 1 115 12.8 5.81 4 4 2 11 7 3 4554406.5 2634447.5 16260.89941 1162519.406 1 1 1 1 response to stimulus Pf07686 667865 ENSMUSG00000095794.2 Igkv6-17 6 0 High Q99LC5 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Mus musculus OX=10090 GN=Etfa PE=1 SV=2" 0 44.118 50 11 50 11 333 35 8.38 4 6 3 4 7 3 2379090.586 2999335.863 891887.8252 2090498.52 11 10 8 10 metabolic process;transport mitochondrion;organelle lumen catalytic activity;nucleotide binding;protein binding "Pf00766, Pf01012" 110842 ENSMUSG00000032314.14 Etfa 9 Respiratory electron transport 0 High P62806 Histone H4 OS=Mus musculus OX=10090 GN=H4c1 PE=1 SV=2 0 20.079 51 5 49 5 103 11.4 11.36 3 3 2 4 4 3 1081688.313 1030084.859 129182.3359 927002.7813 3 3 2 3 cell organization and biogenesis;metabolic process;regulation of biological process chromosome;membrane;nucleus DNA binding;protein binding;RNA binding "Pf00125, Pf02969, Pf15630" 320332; 326619; 319160; 319155; 319158; 319161; 69386; 319157; 319159; 326620; 100041230; 319156; 97122; 102641229 ENSMUSG00000096010.2; ENSMUSG00000091405.2; ENSMUSG00000060981.6; ENSMUSG00000069274.3; ENSMUSG00000061482.6; ENSMUSG00000067455.5; ENSMUSG00000064288.4; ENSMUSG00000060678.4; ENSMUSG00000069306.5; ENSMUSG00000069305.3; ENSMUSG00000069266.5; ENSMUSG00000060093.6; ENSMUSG00000060639.5 Hist4h4; Hist1h4a; Hist1h4k; Hist1h4c; Hist1h4i; Hist1h4n; Hist1h4h; Hist1h4f; Hist1h4j; Hist1h4b; Hist1h4m; Hist1h4d; Hist2h4; LOC100862646; LOC102641229 6; 13; 3 Transcriptional regulation by small RNAs; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HATs acetylate histones; Meiotic Recombination; HDMs demethylate histones; Deposition of new CENPA-containing nucleosomes at the centromere; Formation of the beta-catenin:TCF transactivating complex; PRC2 methylates histones and DNA; SUMOylation of chromatin organization proteins; Nonhomologous End-Joining (NHEJ); RMTs methylate histone arginines; NoRC negatively regulates rRNA expression; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Oxidative Stress Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); DNA Damage/Telomere Stress Induced Senescence; SIRT1 negatively regulates rRNA expression; Condensation of Prophase Chromosomes; B-WICH complex positively regulates rRNA expression; RNA Polymerase I Promoter Opening; NoRC negatively regulates rRNA expression; Meiotic Synapsis; G2/M DNA damage checkpoint; PKMTs methylate histone lysines; Mus musculus biological processes; RNA Polymerase I Chain Elongation Alcoholism; Systemic lupus erythematosus; Viral carcinogenesis 0 High P18528 Ig heavy chain V region 6.96 OS=Mus musculus OX=10090 PE=4 SV=1 0 24.165 31 2 47 1 98 11 7.93 2 2 1 1 8 8 1 3 5212065.25 11579438.5 325293.5156 1079199.453 1 1 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 777688 Gm16971; Ighv5-4 12 0 High A0A140T8M2 Immunoglobulin kappa variable 12-44 (Fragment) OS=Mus musculus OX=10090 GN=Igkv12-44 PE=4 SV=2 0 19.587 41 4 46 3 115 12.5 7.87 4 3 1 3 8 6 1 3 5072778.563 7913730.281 1387064.984 1059627.781 4 5 4 4 "Pf00047, Pf07679, Pf07686" 545851 ENSMUSG00000096422.2 Igkv12-44 6 1 High P17182 Alpha-enolase OS=Mus musculus OX=10090 GN=Eno1 PE=1 SV=3 0 42.693 36 10 45 10 434 47.1 6.8 3 2 3 4 2 3 1754491.428 1582031.568 924643.4688 731275.4609 10 8 5 9 metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;cytosol;membrane;nucleus catalytic activity;DNA binding;metal ion binding;protein binding;RNA binding "Pf00113, Pf03952, Pf13378" 13806; 433182 ENSMUSG00000059040.4; ENSMUSG00000063524.13 Eno1; Gm5506; Eno1b 4; 18 Gluconeogenesis; Glycolysis RNA degradation; Metabolic pathways; Biosynthesis of amino acids; Glycolysis / Gluconeogenesis; HIF-1 signaling pathway; Carbon metabolism 0 High P01898 "H-2 class I histocompatibility antigen, Q10 alpha chain OS=Mus musculus OX=10090 GN=H2-Q10 PE=1 SV=3" 0 41.108 42 11 37 7 325 37.2 5.25 3 3 47954.48828 9120.381836 238700.9844 1 1 4 cell surface;endoplasmic reticulum;Golgi;membrane protein binding;RNA binding "Pf00129, Pf07654, Pf08205" 15007 ENSMUSG00000067235.14 H2-Q10 17 Endocytosis; Herpes simplex infection; Allograft rejection; Epstein-Barr virus infection; Cell adhesion molecules (CAMs); HTLV-I infection; Phagosome; Graft-versus-host disease; Viral myocarditis; Antigen processing and presentation; Type I diabetes mellitus; Autoimmune thyroid disease; Viral carcinogenesis 0 High A6BLY7 "Keratin, type I cytoskeletal 28 OS=Mus musculus OX=10090 GN=Krt28 PE=1 SV=1" 0 6.851 3 2 37 1 462 50.3 5.29 1 1 1 2 2 1 1 3 179119.499 153017.5313 55800.92969 100417.4063 3 1 1 1 cytoplasm structural molecule activity Pf00038 70843 ENSMUSG00000055937.1 Krt28 11 Formation of the cornified envelope 0 High Q8K297 Procollagen galactosyltransferase 1 OS=Mus musculus OX=10090 GN=Colgalt1 PE=1 SV=2 0 39.398 27 13 36 13 617 71 7.28 3 3 177213.3308 69011.14355 1175038.238 3 3 11 endoplasmic reticulum;membrane;organelle lumen catalytic activity Pf01755 234407 ENSMUSG00000034807.9 Glt25d1; Colgalt1 8 Collagen biosynthesis and modifying enzymes Lysine degradation; Other types of O-glycan biosynthesis 0 High Q9DBG6 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Mus musculus OX=10090 GN=Rpn2 PE=1 SV=1 0 42.978 37 12 36 12 631 69 5.81 3 3 55836.7168 211202.3047 61071.40527 1111957.641 2 3 2 8 metabolic process;response to stimulus endoplasmic reticulum;membrane catalytic activity Pf05817 20014 ENSMUSG00000027642.15 Rpn2 2 Metabolic pathways; N-Glycan biosynthesis; Protein processing in endoplasmic reticulum 0 High P79568 Class Ib MHC antigen Qa-2 OS=Mus musculus OX=10090 GN=H2-Q6 PE=1 SV=1 0 31.888 37 12 35 5 326 37.4 6.24 3 3 55992.35645 25011.58398 765482.5703 4 1 5 cell surface;endoplasmic reticulum;Golgi;membrane protein binding;RNA binding "Pf00129, Pf07654, Pf08205" 110557 ENSMUSG00000073409.12 H2-Q6 17 Endocytosis; Herpes simplex infection; Allograft rejection; Epstein-Barr virus infection; Cell adhesion molecules (CAMs); HTLV-I infection; Phagosome; Graft-versus-host disease; Viral myocarditis; Antigen processing and presentation; Type I diabetes mellitus; Autoimmune thyroid disease; Viral carcinogenesis 7 High Q91Y06 Protocadherin beta 13 OS=Mus musculus OX=10090 GN=Pcdhb13 PE=2 SV=1 0.002 3.966 3 1 32 1 796 87.5 4.86 1 1 1 1 2 3 1612264850 1274461098 788030745 966345452.1 2 2 2 2 cell communication;cell organization and biogenesis membrane metal ion binding "Pf00028, Pf08266" 93884 ENSMUSG00000047307.2 Pcdhb13 18 0 High E9PWT4 "H-2 class I histocompatibility antigen, Q7 alpha chain OS=Mus musculus OX=10090 GN=H2-Q7 PE=3 SV=2" 0 22.438 32 9 30 2 310 35.2 6.13 3 3 19392.79102 11657.74512 18141.83984 1 1 1 response to stimulus cell surface;endoplasmic reticulum;Golgi;membrane protein binding;RNA binding "Pf00129, Pf07654, Pf08205" 15018 ENSMUSG00000060550.15 H2-Q7 17 0 High A0A075B5S2 Immunoglobulin heavy variable 7-1 (Fragment) OS=Mus musculus OX=10090 GN=Ighv7-1 PE=1 SV=2 0 19.296 38 4 29 2 121 13.6 8.29 4 3 2 6 3 3 4808551.5 4098705.324 311934.9492 1007936.656 4 4 3 3 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000076665.4 LOC674141 12 2 High A0A0R4J083 "Long-chain-specific acyl-CoA dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Acadl PE=1 SV=1" 0 23.322 29 10 29 10 430 47.9 8.15 8 6 1 2 9 10 1 3 3075559.289 5789544.266 1339769.33 1094457.766 8 8 7 8 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf00441, Pf02770, Pf02771, Pf08028" 11363 ENSMUSG00000026003.5 Acadl 1 Beta oxidation of myristoyl-CoA to lauroyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA PPAR signaling pathway; Fatty acid metabolism; Metabolic pathways; Fatty acid degradation 0 High A0A075B5R7 Immunoglobulin heavy variable 14-2 (Fragment) OS=Mus musculus OX=10090 GN=Ighv14-2 PE=4 SV=1 0 11.733 32 4 27 2 117 13 6.04 3 2 2 5 3 3 2528142.227 3890379.781 392413.8594 699025.0664 4 4 4 4 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding "Pf00047, Pf07686" ENSMUSG00000095583.1 LOC674140 12 2 High Q9R0E1 Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 OS=Mus musculus OX=10090 GN=Plod3 PE=1 SV=1 0 29.391 16 10 22 10 741 84.9 6.23 3 3 294829.76 119298.3462 17249.14844 692537.3975 6 5 1 8 cell organization and biogenesis;metabolic process;response to stimulus endoplasmic reticulum;Golgi;membrane catalytic activity;metal ion binding Pf03171 26433 ENSMUSG00000004846.10 Plod3 5 Collagen biosynthesis and modifying enzymes Lysine degradation; Other types of O-glycan biosynthesis 0 High Q9CQA3 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Mus musculus OX=10090 GN=Sdhb PE=1 SV=1" 0 17.345 34 8 22 8 282 31.8 8.68 5 5 1 3 5 7 1 3 1539723.016 3192631.453 613595.1055 1048480.223 8 8 4 7 metabolic process;transport membrane;mitochondrion catalytic activity;metal ion binding "Pf13085, Pf13183, Pf13534" 67680 ENSMUSG00000009863.14 Sdhb 4 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Carbon metabolism 0 High P01679 Ig kappa chain V-VI region J539 OS=Mus musculus OX=10090 PE=1 SV=1 0 11.905 37 3 19 2 107 11.5 8.46 2 1 2 3 2 3 1018899.621 835838.1797 13843.80664 612420.9375 2 2 1 2 Pf07686 0 High Q60668 Heterogeneous nuclear ribonucleoprotein D0 OS=Mus musculus OX=10090 GN=Hnrnpd PE=1 SV=2 0 15.116 20 6 18 5 355 38.3 7.81 4 3 6 3 271954.5044 5255040.953 451366.0273 1110187.766 3 5 4 5 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;nucleus DNA binding;protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 11991 ENSMUSG00000000568.15 Hnrnpd 5 mRNA Splicing - Major Pathway; AUF1 (hnRNP D0) binds and destabilizes mRNA 1 High S4R1X1 WD repeat-containing protein 91 OS=Mus musculus OX=10090 GN=Wdr91 PE=1 SV=1 0 19.956 13 5 17 5 604 67.7 6.67 2 2 3 3 279072.3669 1912310.648 441546.3984 1014705.477 3 4 4 3 protein binding Pf00400 ENSMUSG00000058486.11 6 0 High A0A2R8VHK1 "Cytochrome c1, heme protein, mitochondrial (Fragment) OS=Mus musculus OX=10090 GN=Cyc1 PE=1 SV=1" 0 15.64 39 4 17 4 165 17.9 5.47 1 2 1 3 369436.5352 344690.3672 455953.4531 694576.0742 4 3 3 4 0 High Q60715 Prolyl 4-hydroxylase subunit alpha-1 OS=Mus musculus OX=10090 GN=P4ha1 PE=1 SV=2 0 31.034 24 10 13 10 534 60.9 5.9 3 3 390107.4373 48883.4375 2757.054688 903877.8906 4 3 1 7 cell organization and biogenesis;metabolic process endoplasmic reticulum;membrane;mitochondrion;organelle lumen catalytic activity;metal ion binding;protein binding "Pf03171, Pf08336" 18451 ENSMUSG00000019916.14 P4ha1 10 Collagen biosynthesis and modifying enzymes Arginine and proline metabolism; Metabolic pathways 0 High Q8R2R1 Protein O-mannosyl-transferase 1 OS=Mus musculus OX=10090 GN=Pomt1 PE=1 SV=1 0 20.778 5 3 7 3 746 85.2 8.29 2 3 47323.76563 487787.3789 1 3 cell organization and biogenesis;metabolic process;response to stimulus endoplasmic reticulum;membrane catalytic activity "Pf02366, Pf02815, Pf13231" 99011 ENSMUSG00000039254.16 Pomt1 2 O-linked glycosylation Other types of O-glycan biosynthesis 0 High Q62087 Serum paraoxonase/lactonase 3 OS=Mus musculus OX=10090 GN=Pon3 PE=1 SV=2 0.002 5.167 7 2 4 2 354 39.3 5.74 2 3 523983.3047 2 metabolic process;regulation of biological process;response to stimulus extracellular catalytic activity;metal ion binding;protein binding "Pf01731, Pf03088" 269823 ENSMUSG00000029759.9 Pon3 6 Synthesis of 5-eicosatetraenoic acids Metabolic pathways 0 High Q8BFZ3 Beta-actin-like protein 2 OS=Mus musculus OX=10090 GN=Actbl2 PE=1 SV=1 0 142.14 42 13 566 3 376 42 5.49 4 4 1 3 5 5 1 4 98268.33569 1400417.125 70296.61719 3 1 1 cytoplasm;cytoskeleton nucleotide binding Pf00022 238880 ENSMUSG00000055194.3 Actbl2 13 0 High Q9D6F9 Tubulin beta-4A chain OS=Mus musculus OX=10090 GN=Tubb4a PE=1 SV=3 0 168.712 62 21 265 1 444 49.6 4.88 3 1 4 3 1 4 145040.2344 1 Met-loss [N-Term] cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton;nucleus catalytic activity;metal ion binding;nucleotide binding;structural molecule activity "Pf00091, Pf03953, Pf10644" 22153 ENSMUSG00000062591.5 Tubb4a 17 Anchoring of the basal body to the plasma membrane; Intraflagellar transport; Hedgehog 'on' state; AURKA Activation by TPX2; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Hedgehog 'off' state; Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes Phagosome; Gap junction 0 High G5E8R3 Pyruvate carboxylase OS=Mus musculus OX=10090 GN=Pcx PE=1 SV=1 0 211.261 49 41 198 41 1178 129.6 6.71 18 10 3 26 14 4 8075123.349 5076159.807 2069692.64 1772133.735 36 25 18 22 metabolic process;regulation of biological process cytoplasm;membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00289, Pf00364, Pf00682, Pf02222, Pf02436, Pf02785, Pf02786, Pf07478, Pf08443, Pf13533, Pf13535, Pf15632" 18563 ENSMUSG00000024892.15 Pcx 19 Biotin transport and metabolism; Gluconeogenesis 0 High Q8K0E8 Fibrinogen beta chain OS=Mus musculus OX=10090 GN=Fgb PE=1 SV=1 0 150.676 55 20 153 20 481 54.7 7.08 11 6 1 4 13 9 1 4 10659153.44 5396974.14 1083919.973 1551449.842 19 17 10 17 cell organization and biogenesis;coagulation;defense response;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;extracellular protein binding;structural molecule activity "Pf00147, Pf01920, Pf08702" 110135 ENSMUSG00000033831.5 Fgb 3 p130Cas linkage to MAPK signaling for integrins; Integrin cell surface interactions; Regulation of TLR by endogenous ligand; Common Pathway of Fibrin Clot Formation; GRB2:SOS provides linkage to MAPK signaling for Integrins ; Platelet degranulation Platelet activation; Complement and coagulation cascades 0 High A0A0A6YWR2 Ig gamma-1 chain C region secreted form (Fragment) OS=Mus musculus OX=10090 GN=Ighg1 PE=1 SV=1 0 80.997 29 9 142 2 393 43.4 6.44 7 1 1 3 25 1 1 4 17284376.6 5218630.691 2971115.201 1888983.115 12 10 9 10 membrane "Pf07654, Pf08205" ENSMUSG00000076614.7 12 Regulation of Complement cascade; Role of phospholipids in phagocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR activation; Classical antibody-mediated complement activation 10 High A0A0A6YY53 Immunoglobulin heavy constant gamma 2C (Fragment) OS=Mus musculus OX=10090 GN=Ighg2c PE=1 SV=1 0 84.052 33 7 142 6 335 36.5 8.02 7 7 1 3 27 17 1 4 24475011.94 13702432.24 2227517.346 2192708.787 6 6 3 5 defense response;response to stimulus Pf07654 ENSMUSG00000076612.7 LOC100048855 12 Regulation of Complement cascade; Role of phospholipids in phagocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR activation; Classical antibody-mediated complement activation 0 High P15105 Glutamine synthetase OS=Mus musculus OX=10090 GN=Glul PE=1 SV=6 0 112.202 59 19 130 19 373 42.1 7.08 12 4 3 4 20 7 3 4 14992511.54 9769571.044 8286631.996 4114562.069 18 18 16 19 Met-loss+Acetyl [N-Term] cell communication;cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;endoplasmic reticulum;mitochondrion;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00120, Pf03951" 14645 ENSMUSG00000026473.15 Glul 1 Astrocytic Glutamate-Glutamine Uptake And Metabolism; Amino acid synthesis and interconversion (transamination) "GABAergic synapse; Metabolic pathways; Nitrogen metabolism; Biosynthesis of amino acids; Glutamatergic synapse; Alanine, aspartate and glutamate metabolism; Arginine biosynthesis; Glyoxylate and dicarboxylate metabolism" 0 High P01644 Ig kappa chain V-V region HP R16.7 OS=Mus musculus OX=10090 PE=1 SV=1 0 49.544 61 5 117 1 108 11.9 7.97 4 3 2 21 10 4 23451605.3 11894821.99 2123850.555 4204224.481 8 8 5 7 "Pf00047, Pf07679, Pf07686" 56304 Ce9 6 6 High P01647 Ig kappa chain V-V region HP 124E1 OS=Mus musculus OX=10090 PE=1 SV=1 0 38.897 61 5 90 1 108 12 8.46 3 2 2 16 5 4 202779.6719 221812.6484 1 1 cell organization and biogenesis;cellular component movement;defense response;metabolic process;regulation of biological process;response to stimulus;transport extracellular;membrane catalytic activity;protein binding "Pf00047, Pf07679, Pf07686" 0 High Q9QWL7 "Keratin, type I cytoskeletal 17 OS=Mus musculus OX=10090 GN=Krt17 PE=1 SV=3" 0 42.532 24 15 87 3 433 48.1 5.06 2 2 3 2 4 2 3 4 329984.73 785188.2617 251865.9541 444903.5869 9 8 4 3 cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytoskeleton catalytic activity;motor activity;protein binding;receptor activity;signal transducer activity;structural molecule activity "Pf00038, Pf01576, Pf07888" 16667 ENSMUSG00000035557.9 Krt17 11 Formation of the cornified envelope 12 High Q6IFX2 "Keratin, type I cytoskeletal 42 OS=Mus musculus OX=10090 GN=Krt42 PE=1 SV=1" 0 50.779 27 15 87 5 452 50.1 5.16 1 3 2 2 2 4 2 4 197488.6868 1149305.332 108596.7031 118070.7617 5 3 1 2 cytoplasm structural molecule activity "Pf00038, Pf04156, Pf08317, Pf13166, Pf13514" 68239 ENSMUSG00000053654.7 Krt42 11 0 High A0A0A6YYE7 Immunoglobulin kappa variable 4-57 (Fragment) OS=Mus musculus OX=10090 GN=Igkv4-57 PE=4 SV=2 0 30.404 39 3 74 1 117 12.7 8.91 3 3 1 2 9 8 2 4 6136769.461 5637017.031 566389.6348 1658614.504 3 3 2 3 response to stimulus "Pf00047, Pf07686" 235952 ENSMUSG00000076556.3 Igkv4-57 6 2 High Q61414 "Keratin, type I cytoskeletal 15 OS=Mus musculus OX=10090 GN=Krt15 PE=1 SV=2" 0 22.481 13 9 72 1 452 49.1 4.86 2 2 3 2 4 2 3 4 34495.79297 56247.44141 35386.21875 1 1 1 nucleus protein binding;structural molecule activity "Pf00038, Pf12128, Pf13514" 16665 Krt15 11 0 High P19001 "Keratin, type I cytoskeletal 19 OS=Mus musculus OX=10090 GN=Krt19 PE=1 SV=1" 0 14.542 11 7 64 1 403 44.5 5.39 2 2 3 2 4 2 3 4 cell differentiation;cell organization and biogenesis;regulation of biological process;response to stimulus cytoskeleton;membrane protein binding;structural molecule activity Pf00038 16669 ENSMUSG00000020911.14 Krt19 11 Formation of the cornified envelope 0 High P01899 "H-2 class I histocompatibility antigen, D-B alpha chain OS=Mus musculus OX=10090 GN=H2-D1 PE=1 SV=2" 0 46.88 40 12 51 1 362 40.8 6.73 4 4 75372.05835 16968.44336 329562.6028 4 1 5 regulation of biological process;response to stimulus cell surface;endoplasmic reticulum;Golgi;membrane protein binding;RNA binding "Pf00129, Pf06623, Pf07654, Pf08205" 14964 ENSMUSG00000073411.11 H2-D1 17 Endocytosis; Herpes simplex infection; Allograft rejection; Epstein-Barr virus infection; Cell adhesion molecules (CAMs); HTLV-I infection; Phagosome; Graft-versus-host disease; Viral myocarditis; Antigen processing and presentation; Type I diabetes mellitus; Natural killer cell mediated cytotoxicity; Autoimmune thyroid disease; Viral carcinogenesis 6 High P00688 Pancreatic alpha-amylase OS=Mus musculus OX=10090 GN=Amy2 PE=1 SV=2 0 43.864 19 8 49 1 508 57.3 7.28 4 3 2 4 10 6 3 4 18748.89453 104635.5859 18409.52734 1 1 1 metabolic process extracellular catalytic activity;metal ion binding "Pf00128, Pf02806" 109959; 100043688; 100043686; 100043684 ENSMUSG00000074268.4; ENSMUSG00000096770.2; ENSMUSG00000093931.2; ENSMUSG00000096569.2 Amy2a5; Amy2a2; Amy2a3; Amy2a4 3 Digestion of dietary carbohydrate Pancreatic secretion; Carbohydrate digestion and absorption; Metabolic pathways; Starch and sucrose metabolism 0 High A0A075B5L1 Immunoglobulin kappa variable 10-94 (Fragment) OS=Mus musculus OX=10090 GN=Igkv10-94 PE=4 SV=7 0 20.286 37 2 47 2 115 12.6 5.9 2 2 1 10 7 4 3515794 1521900.469 65662.48438 277887.6719 2 2 1 1 response to stimulus "Pf00047, Pf07679, Pf07686" ENSMUSG00000096490.1 6 0 High A0A0B4J1I9 Immunoglobulin kappa variable 4-55 (Fragment) OS=Mus musculus OX=10090 GN=Igkv4-55 PE=1 SV=1 0 19.094 27 2 46 1 117 12.7 6.48 2 2 2 6 6 4 1176161.35 474971.375 173853.625 102992.4063 1 1 1 1 response to stimulus "Pf00047, Pf07686" 385253 ENSMUSG00000096833.2 Igkv4-55 6 0 High Q8JZU2 "Tricarboxylate transport protein, mitochondrial OS=Mus musculus OX=10090 GN=Slc25a1 PE=1 SV=1" 0 32.781 44 10 38 10 311 33.9 9.89 4 4 57149.61719 228817.4063 212721.291 1650553.842 2 5 3 8 transport membrane;mitochondrion;nucleus transporter activity Pf00153 13358 ENSMUSG00000003528.14 Slc25a1 16 Gluconeogenesis; Fatty acyl-CoA biosynthesis 0 High Q8QZT1 "Acetyl-CoA acetyltransferase, mitochondrial OS=Mus musculus OX=10090 GN=Acat1 PE=1 SV=1" 0 28.571 37 11 35 11 424 44.8 8.51 7 5 1 4 9 6 1 4 3871191.664 2911565.156 1667772.199 1536694.852 10 8 6 8 cell organization and biogenesis;metabolic process;response to stimulus membrane;mitochondrion;organelle lumen catalytic activity;metal ion binding;protein binding "Pf00108, Pf00109, Pf02803" 110446 ENSMUSG00000032047.5 Acat1 9 Synthesis of Ketone Bodies; Utilization of Ketone Bodies; Branched-chain amino acid catabolism "Fatty acid metabolism; Pyruvate metabolism; Tryptophan metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Terpenoid backbone biosynthesis; Lysine degradation; Fatty acid degradation; Butanoate metabolism; Propanoate metabolism; Synthesis and degradation of ketone bodies; Carbon metabolism; Glyoxylate and dicarboxylate metabolism" 0 High Q9ESP1 Stromal cell-derived factor 2-like protein 1 OS=Mus musculus OX=10090 GN=Sdf2l1 PE=1 SV=2 0 47.842 57 7 30 7 221 23.6 7.42 3 4 1988029.143 7 metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;membrane;organelle lumen catalytic activity;protein binding Pf02815 64136 ENSMUSG00000022769.7 Sdf2l1 16 0 High Q9QYC7 Vitamin K-dependent gamma-carboxylase OS=Mus musculus OX=10090 GN=Ggcx PE=1 SV=1 0 28.175 14 8 25 8 757 87.1 8.02 4 4 1004877.742 6 metabolic process endoplasmic reticulum;membrane catalytic activity Pf05090 56316 ENSMUSG00000053460.8; ENSMUSG00000103019.2 Ggcx 6; CHR_MG184_PATCH Gamma-carboxylation of protein precursors Ubiquinone and other terpenoid-quinone biosynthesis 0 High P45952 "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Acadm PE=1 SV=1" 0 11.601 14 5 16 5 421 46.5 8.37 5 3 4 5 3 4 2426653.961 2133950.234 852027.2539 2280233.109 5 4 2 4 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion;nucleus;organelle lumen catalytic activity;nucleotide binding;protein binding "Pf00441, Pf02770, Pf02771, Pf08028" 11364 ENSMUSG00000062908.12 Acadm 3 mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA "PPAR signaling pathway; Fatty acid metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Fatty acid degradation; beta-Alanine metabolism; Propanoate metabolism; Carbon metabolism" 0 High P67778 Prohibitin OS=Mus musculus OX=10090 GN=Phb PE=1 SV=1 0 21.123 42 8 16 8 272 29.8 5.76 4 4 70899.58496 170904.7817 33552.2959 1453328.369 3 2 1 5 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;endosome;membrane;mitochondrion;nucleus DNA binding;protein binding Pf01145 18673 ENSMUSG00000038845.11 Phb 11 RAF activation; Interleukin-20 family signaling; Processing of SMDT1 0 High Q925U4 ER degradation-enhancing alpha-mannosidase-like protein 1 OS=Mus musculus OX=10090 GN=Edem1 PE=1 SV=1 0 17.815 10 5 14 5 652 73.7 6.15 3 4 6564.611328 27133.9082 12492.48438 655749.4277 1 1 1 4 metabolic process;response to stimulus endoplasmic reticulum;membrane catalytic activity;metal ion binding;protein binding Pf01532 192193 ENSMUSG00000030104.9 Edem1 6 ER Quality Control Compartment (ERQC) Protein processing in endoplasmic reticulum 0 High P40142 Transketolase OS=Mus musculus OX=10090 GN=Tkt PE=1 SV=1 0 9.684 9 3 6 3 623 67.6 7.5 1 2 1 4 245234.3242 130464.4648 11709.37695 962765.5625 2 2 1 3 metabolic process;regulation of biological process membrane catalytic activity;metal ion binding;protein binding "Pf00456, Pf00676, Pf02779, Pf02780" 21881 ENSMUSG00000021957.6 Tkt 14 Pentose phosphate pathway (hexose monophosphate shunt); Insulin effects increased synthesis of Xylulose-5-Phosphate Metabolic pathways; Biosynthesis of amino acids; Pentose phosphate pathway; Carbon metabolism 0 High O09164 Extracellular superoxide dismutase [Cu-Zn] OS=Mus musculus OX=10090 GN=Sod3 PE=1 SV=1 0 6.568 11 2 4 2 251 27.4 6.84 2 4 41893.16797 297707.3203 883974.9688 2 2 2 metabolic process;response to stimulus cytoplasm;extracellular;nucleus;organelle lumen antioxidant activity;catalytic activity;metal ion binding;protein binding Pf00080 20657 ENSMUSG00000072941.5 Sod3 5 Detoxification of Reactive Oxygen Species 0 High Q6IFZ6 "Keratin, type II cytoskeletal 1b OS=Mus musculus OX=10090 GN=Krt77 PE=1 SV=1" 0 24.927 7 4 157 1 572 61.3 8.02 3 2 2 2 6 14 4 5 3118116.738 7462736.328 1127786.969 1672384.522 1 1 1 1 cytoskeleton protein binding;structural molecule activity "Pf00038, Pf09728, Pf13166" 406220 ENSMUSG00000067594.5 Krt77 15 Formation of the cornified envelope 0 High P04104 "Keratin, type II cytoskeletal 1 OS=Mus musculus OX=10090 GN=Krt1 PE=1 SV=4" 0 31.732 5 4 155 2 637 65.6 8.15 4 3 2 3 6 14 3 5 9888658.65 68397496.56 4346065.924 10865332.71 5 5 4 6 defense response;metabolic process;regulation of biological process;response to stimulus cytoskeleton;membrane;nucleus structural molecule activity "Pf00038, Pf11853" 16678 ENSMUSG00000046834.6 Krt1 15 Formation of the cornified envelope; Neutrophil degranulation 3 High Q9WTX5 S-phase kinase-associated protein 1 OS=Mus musculus OX=10090 GN=Skp1 PE=1 SV=3 0 62.95 70 11 93 11 163 18.7 4.54 5 2 4 5 3 5 129048.8594 3010790.621 2135053.661 1744931.359 1 9 8 9 cell organization and biogenesis;metabolic process cytoplasm;cytosol;nucleus catalytic activity;protein binding "Pf01466, Pf03931" 21402 ENSMUSG00000036309.14 Skp1a 11 NIK-->noncanonical NF-kB signaling; Degradation of beta-catenin by the destruction complex; Prolactin receptor signaling; SCF-beta-TrCP mediated degradation of Emi1; Regulation of RUNX2 expression and activity; SCF(Skp2)-mediated degradation of p27/p21; Neddylation; GLI3 is processed to GLI3R by the proteasome; Dectin-1 mediated noncanonical NF-kB signaling; Activation of NF-kappaB in B cells; Activated TLR4 signalling; Antigen processing: Ubiquitination & Proteasome degradation; Degradation of GLI1 by the proteasome; FCERI mediated NF-kB activation; Regulation of PLK1 Activity at G2/M Transition; Downstream TCR signaling; Cyclin D associated events in G1; Interleukin-1 family signaling; Iron uptake and transport; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; MAP3K8 (TPL2)-dependent MAPK1/3 activation Herpes simplex infection; Wnt signaling pathway; Ubiquitin mediated proteolysis; Circadian rhythm; Oocyte meiosis; Cell cycle; TGF-beta signaling pathway; Protein processing in endoplasmic reticulum 0 High A0A0B4J1J7 Immunoglobulin heavy variable 1-82 OS=Mus musculus OX=10090 GN=Ighv1-82 PE=1 SV=1 0 34.327 55 4 84 3 98 10.6 9.29 4 4 1 2 11 10 1 5 44754057.41 34388786.27 2013467.961 4861669 4 3 2 2 Pf07686 16061 ENSMUSG00000095127.2 Igh-VJ558 12 0 High Q8BH95 "Enoyl-CoA hydratase, mitochondrial OS=Mus musculus OX=10090 GN=Echs1 PE=1 SV=1" 0 34.72 25 6 50 6 290 31.5 8.48 6 3 3 11 4 5 3229566.303 3423423.875 1911023.602 2468051.289 6 4 7 6 metabolic process mitochondrion;organelle lumen catalytic activity Pf00378 93747 ENSMUSG00000025465.13 Echs1 7 Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA "Fatty acid metabolism; Tryptophan metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Lysine degradation; Fatty acid degradation; Butanoate metabolism; beta-Alanine metabolism; Propanoate metabolism; Fatty acid elongation; Carbon metabolism" 0 High Q60936 "Atypical kinase COQ8A, mitochondrial OS=Mus musculus OX=10090 GN=Coq8a PE=1 SV=2" 0 28.368 20 8 23 8 645 71.7 6.54 1 2 3 1 2 5 910359.2891 1693323.988 138943.5918 1533899.641 8 8 3 7 metabolic process membrane;mitochondrion catalytic activity;nucleotide binding Pf03109 67426 ENSMUSG00000026489.13 Adck3; Coq8a 1 0 High P83741 Serine/threonine-protein kinase WNK1 OS=Mus musculus OX=10090 GN=Wnk1 PE=1 SV=2 0 11.006 4 6 17 6 2377 250.8 6.43 6 1 4 7 1 5 2060668.547 522789.7344 1238069.336 6 4 6 metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;membrane catalytic activity;enzyme regulator activity;metal ion binding;nucleotide binding;protein binding "Pf00069, Pf07714, Pf09770, Pf12202" 232341 ENSMUSG00000045962.16 Wnk1 6 Stimuli-sensing channels 0 High P12242 Mitochondrial brown fat uncoupling protein 1 OS=Mus musculus OX=10090 GN=Ucp1 PE=1 SV=2 0 14.123 25 6 16 6 307 33.2 9.14 6 3 4 7 4 5 1210707.758 1369245.477 244015.8633 1297058.117 6 5 3 6 Met-loss [N-Term] cell differentiation;regulation of biological process;response to stimulus;transport membrane;mitochondrion nucleotide binding;protein binding;transporter activity Pf00153 22227 ENSMUSG00000031710.4 Ucp1 8 The proton buffering model; The fatty acid cycling model PPAR signaling pathway; Huntington's disease 0 High Q03265 "ATP synthase subunit alpha, mitochondrial OS=Mus musculus OX=10090 GN=Atp5f1a PE=1 SV=1" 0 174.831 56 27 303 27 553 59.7 9.19 3 1 5 3 2 6 2232667.135 2527651.854 1610192.422 2442818.885 17 10 8 16 metabolic process;regulation of biological process;transport membrane;mitochondrion catalytic activity;nucleotide binding;protein binding;RNA binding;transporter activity "Pf00006, Pf00306, Pf02663, Pf02874, Pf05943" 11946 ENSMUSG00000025428.15 Atp5a1 18 Cristae formation; Formation of ATP by chemiosmotic coupling Metabolic pathways; Huntington's disease; Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High P11499 Heat shock protein HSP 90-beta OS=Mus musculus OX=10090 GN=Hsp90ab1 PE=1 SV=3 0 157.492 40 26 220 12 724 83.2 5.03 1 2 1 6 466589.9863 615231.0034 21235.18945 336723.9504 10 12 1 12 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;cytosol;extracellular;membrane;mitochondrion;nucleus enzyme regulator activity;nucleotide binding;protein binding;RNA binding "Pf00183, Pf02518, Pf13589" 15516 ENSMUSG00000023944.14 Hsp90ab1 17 The role of GTSE1 in G2/M progression after G2 checkpoint; HSF1 activation; Attenuation phase; Neutrophil degranulation; The NLRP3 inflammasome; HSP90 chaperone cycle for steroid hormone receptors (SHR); Regulation of actin dynamics for phagocytic cup formation; Aryl hydrocarbon receptor signalling; Sema3A PAK dependent Axon repulsion Progesterone-mediated oocyte maturation; NOD-like receptor signaling pathway; Pathways in cancer; Antigen processing and presentation; PI3K-Akt signaling pathway; Protein processing in endoplasmic reticulum; Estrogen signaling pathway; Prostate cancer 13 High Q6P3A8 "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial OS=Mus musculus OX=10090 GN=Bckdhb PE=1 SV=2" 0 148.035 63 16 147 16 390 42.9 6.7 9 5 6 15 9 6 7593161.426 4988596.246 2444070.064 3764425.075 14 13 10 16 metabolic process membrane;mitochondrion;organelle lumen catalytic activity;protein binding "Pf02779, Pf02780" 12040 ENSMUSG00000032263.14 Bckdhb 9 Glyoxylate metabolism and glycine degradation; Branched-chain amino acid catabolism "Valine, leucine and isoleucine degradation; Metabolic pathways; Propanoate metabolism" 0 High Q925I1 ATPase family AAA domain-containing protein 3 OS=Mus musculus OX=10090 GN=Atad3 PE=1 SV=1 0 91.272 43 23 130 23 591 66.7 9.29 2 2 5 2 2 6 1062134.793 998100.6543 285535.2598 2935183.581 14 7 5 19 Met-loss+Acetyl [N-Term] cell growth;regulation of biological process membrane;mitochondrion catalytic activity;nucleotide binding;RNA binding "Pf00004, Pf00910, Pf01078, Pf05707, Pf06745, Pf07728, Pf12037, Pf13207, Pf13401" 108888 ENSMUSG00000029036.18 Atad3a 4 Neutrophil degranulation 0 High P14106 Complement C1q subcomponent subunit B OS=Mus musculus OX=10090 GN=C1qb PE=1 SV=2 0 59.074 36 7 88 7 253 26.7 8.15 6 3 3 13 5 6 9694495.6 3170566.641 643567.6953 1784704.262 8 5 2 7 defense response;metabolic process;regulation of biological process;response to stimulus extracellular;membrane protein binding "Pf00229, Pf00386" 12260 ENSMUSG00000036905.8 C1qb 4 Regulation of Complement cascade; Classical antibody-mediated complement activation Chagas disease (American trypanosomiasis); Staphylococcus aureus infection; Complement and coagulation cascades; Pertussis; Prion diseases; Systemic lupus erythematosus 0 High Q02105 Complement C1q subcomponent subunit C OS=Mus musculus OX=10090 GN=C1qc PE=1 SV=2 0 53.836 30 6 85 6 246 26 8.54 5 3 1 4 9 6 1 6 5476198.962 5667947.823 832909.4922 1856517.984 6 5 4 4 defense response;metabolic process;regulation of biological process;response to stimulus extracellular;membrane protein binding "Pf00229, Pf00386, Pf01391" 12262 ENSMUSG00000036896.5 C1qc 4 Regulation of Complement cascade; Classical antibody-mediated complement activation Chagas disease (American trypanosomiasis); Staphylococcus aureus infection; Complement and coagulation cascades; Pertussis; Prion diseases; Systemic lupus erythematosus 0 High Q91VT8 Small integral membrane protein 14 OS=Mus musculus OX=10090 GN=Smim14 PE=1 SV=1 0 62.365 57 3 56 3 99 10.7 5.73 3 6 198033.1816 262761.5801 10398024.24 4 3 4 Met-loss [N-Term]; Met-loss+Acetyl [N-Term] endoplasmic reticulum;membrane Pf11027 68552 ENSMUSG00000037822.12 1110003E01Rik; Smim14 5 0 High P42125 "Enoyl-CoA delta isomerase 1, mitochondrial OS=Mus musculus OX=10090 GN=Eci1 PE=1 SV=2" 0 29.807 27 7 47 7 289 32.2 8.98 5 5 1 4 10 11 1 6 3976162.914 6734658.734 2099623.875 2421716.797 7 7 5 6 metabolic process membrane;mitochondrion;organelle lumen catalytic activity;protein binding Pf00378 13177 ENSMUSG00000024132.5 Eci1 17 mitochondrial fatty acid beta-oxidation of unsaturated fatty acids Fatty acid degradation 0 High Q9D051 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Mus musculus OX=10090 GN=Pdhb PE=1 SV=1" 0 25.79 32 8 24 8 359 38.9 6.87 8 6 6 10 7 6 4510347.063 1423247.898 784466.1133 2013124.928 8 6 5 8 metabolic process mitochondrion;nucleus;organelle lumen catalytic activity "Pf02779, Pf02780" 68263 ENSMUSG00000021748.8 Pdhb 14 Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Glyoxylate metabolism and glycine degradation Pyruvate metabolism; Citrate cycle (TCA cycle); Metabolic pathways; Glycolysis / Gluconeogenesis; HIF-1 signaling pathway; Carbon metabolism; Central carbon metabolism in cancer; Glucagon signaling pathway 0 High B2RXT3 Ogdhl protein OS=Mus musculus OX=10090 GN=Ogdhl PE=1 SV=1 0 11.293 5 6 14 1 1010 114.5 6.84 5 2 4 6 2 6 394882.3438 502927.3125 154060.3594 1 1 1 metabolic process mitochondrion catalytic activity "Pf00676, Pf02779" 239017 Ogdhl 14 0 High Q9DCD0 "6-phosphogluconate dehydrogenase, decarboxylating OS=Mus musculus OX=10090 GN=Pgd PE=1 SV=3" 0 7.403 11 4 6 4 483 53.2 7.23 4 6 10248.54419 1010381.266 2 4 metabolic process cytoplasm;nucleus catalytic activity;nucleotide binding "Pf00393, Pf03446" 110208 ENSMUSG00000028961.15 Pgd 4 Pentose phosphate pathway (hexose monophosphate shunt) Glutathione metabolism; Metabolic pathways; Pentose phosphate pathway; Carbon metabolism 0 High P00687 Alpha-amylase 1 OS=Mus musculus OX=10090 GN=Amy1 PE=1 SV=2 0 181.62 70 24 164 17 511 57.6 6.96 14 13 5 6 28 18 6 7 12498739.7 9164251.472 4231382.722 4287869.604 25 21 18 21 metabolic process extracellular catalytic activity;metal ion binding "Pf00128, Pf02806" 11722 ENSMUSG00000074264.12 Amy1 3 Digestion of dietary carbohydrate Carbohydrate digestion and absorption; Metabolic pathways; Starch and sucrose metabolism 7 High Q62191 E3 ubiquitin-protein ligase TRIM21 OS=Mus musculus OX=10090 GN=Trim21 PE=1 SV=1 0 96.07 44 18 152 1 470 54.1 7.08 1 4 1 7 1 4 1 7 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus;vacuole catalytic activity;DNA binding;metal ion binding;protein binding;RNA binding "Pf00097, Pf00622, Pf00643, Pf13445, Pf13639, Pf13765, Pf13920, Pf13923, Pf14634, Pf14835, Pf15227" 20821 Trim21 7 0 High Q9WUM5 "Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial OS=Mus musculus OX=10090 GN=Suclg1 PE=1 SV=4" 0 55.555 34 10 115 10 346 36.1 9.39 8 3 3 3 14 9 3 7 7357943.233 6347884.075 2140613.875 5048651.417 11 7 7 9 metabolic process cytosol;membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00549, Pf02629, Pf13607" 56451 ENSMUSG00000052738.14 Suclg1 6 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Propanoate metabolism; Carbon metabolism 0 High A8DUK4 Beta-globin OS=Mus musculus OX=10090 GN=Hbb-bs PE=1 SV=1 0 70.428 78 11 107 11 147 15.7 7.69 10 7 2 6 20 11 3 7 10523158.57 5944398.016 2710752.027 2051301.063 11 10 6 8 regulation of biological process;transport antioxidant activity;catalytic activity;metal ion binding;protein binding;transporter activity Pf00042 100503605; 101488143; 15129 ENSMUSG00000073940.3; ENSMUSG00000052305.6 Beta-s; Hbb-bs; Hbb-bt; Hbb-b1 7 Erythrocytes take up carbon dioxide and release oxygen; Neutrophil degranulation; Factors involved in megakaryocyte development and platelet production; Erythrocytes take up oxygen and release carbon dioxide; Scavenging of heme from plasma African trypanosomiasis; Malaria 0 High A0A075B5M7 Immunoglobulin kappa variable 5-39 OS=Mus musculus OX=10090 GN=Igkv5-39 PE=1 SV=7 0 31.051 47 3 66 2 95 10.3 6.25 3 3 1 3 15 9 1 7 20093655.63 14129038.12 887250.8906 2932942.241 5 4 3 4 "Pf00047, Pf07679, Pf07686" ENSMUSG00000076569.3 6 2 High Q62425 Cytochrome c oxidase subunit NDUFA4 OS=Mus musculus OX=10090 GN=Ndufa4 PE=1 SV=2 0 14.499 38 4 36 4 82 9.3 9.52 2 3 4 3 5 7 1374015 3275385.016 713602.3125 3321064.672 3 3 3 4 metabolic process;transport membrane;mitochondrion catalytic activity;protein binding;transporter activity Pf06522 17992 ENSMUSG00000029632.7 Ndufa4 6 Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High Q64521 "Glycerol-3-phosphate dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Gpd2 PE=1 SV=2" 0 29.908 19 11 32 11 727 80.9 6.61 9 7 2 7 14 9 2 7 2400367.418 2255347.965 1224896.934 1660282.262 10 10 9 10 metabolic process membrane;mitochondrion catalytic activity;metal ion binding "Pf00890, Pf01266, Pf03486, Pf07992, Pf12831, Pf13499" 14571 ENSMUSG00000026827.12 Gpd2 2 Triglyceride catabolism; Synthesis of PA Glycerophospholipid metabolism 0 High Q8CGN5 Perilipin-1 OS=Mus musculus OX=10090 GN=Plin1 PE=1 SV=2 0 18.591 24 8 22 8 517 55.6 7.01 4 7 6 4 11 7 1950094.813 2490286.594 650962.5508 2157961.555 7 8 4 8 metabolic process cytosol;endoplasmic reticulum protein binding Pf03036 103968 ENSMUSG00000030546.14 Plin1 7 PPAR signaling pathway; Regulation of lipolysis in adipocytes 0 High Q9Z1R9 "Protease, serine 1 (trypsin 1) OS=Mus musculus OX=10090 GN=Prss1 PE=1 SV=1" 0 30.038 8 1 178 1 246 26.1 4.94 1 1 1 1 16 15 5 8 66599884.94 77907120.75 31606450.63 25996947.89 2 2 2 2 metabolic process catalytic activity Pf00089 114228 ENSMUSG00000062751.5 Prss1 6 "Cobalamin (Cbl, vitamin B12) transport and metabolism; Neutrophil degranulation; Collagen degradation; Antimicrobial peptides; Activation of Matrix Metalloproteinases" 0 High Q3U7K7 E3 ubiquitin-protein ligase TRIM21 OS=Mus musculus OX=10090 GN=Trim21 PE=1 SV=1 0 89.296 46 19 153 2 462 53.3 6.7 1 4 1 8 1 4 1 8 615111.8115 1525537.066 1390335.387 2197723.435 11 12 11 15 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus catalytic activity;DNA binding;metal ion binding;protein binding;RNA binding "Pf00097, Pf00622, Pf00643, Pf13445, Pf13639, Pf13765, Pf13920, Pf13923, Pf14634, Pf14835, Pf15227" 20821 ENSMUSG00000030966.13 Trim21 7 Antigen processing: Ubiquitination & Proteasome degradation; Regulation of innate immune responses to cytosolic DNA Systemic lupus erythematosus 19 High Q8VCT4 Carboxylesterase 1D OS=Mus musculus OX=10090 GN=Ces1d PE=1 SV=1 0 27.434 21 9 19 7 565 61.7 6.61 1 6 1 8 478584.5078 208812.8418 4259003.199 4 4 6 cell differentiation;cell organization and biogenesis;metabolic process;response to stimulus cytoplasm;cytosol;endoplasmic reticulum;organelle lumen catalytic activity "Pf00135, Pf00326, Pf00756, Pf07859, Pf12695" 104158 ENSMUSG00000056973.6 Ces1d 8 Phase I - Functionalization of compounds Metabolic pathways; Drug metabolism - other enzymes 0 High Q60994 Adiponectin OS=Mus musculus OX=10090 GN=Adipoq PE=1 SV=2 0 8.304 19 4 8 4 247 26.8 5.57 4 8 2998.695801 22610.43555 2262506.703 1 2 4 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cell surface;endoplasmic reticulum;extracellular protein binding "Pf00386, Pf01391" 11450 ENSMUSG00000022878.5 Adipoq 16 AMPK inhibits chREBP transcriptional activation activity PPAR signaling pathway; Type II diabetes mellitus; Longevity regulating pathway; Non-alcoholic fatty liver disease (NAFLD); Adipocytokine signaling pathway; AMPK signaling pathway 0 High P68134 "Actin, alpha skeletal muscle OS=Mus musculus OX=10090 GN=Acta1 PE=1 SV=1" 0 242.132 73 26 1061 3 377 42 5.39 10 8 2 6 18 14 2 9 2610627.563 1714492 159991.8149 928354.6702 9 9 4 5 cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytoskeleton nucleotide binding;protein binding Pf00022 11459 ENSMUSG00000031972.5 Acta1 8 Striated Muscle Contraction 12 High P62737 "Actin, aortic smooth muscle OS=Mus musculus OX=10090 GN=Acta2 PE=1 SV=1" 0 218.247 80 26 943 2 377 42 5.39 9 7 2 6 16 12 2 9 88081.36328 21136.7207 7389.794922 2 1 1 regulation of biological process;response to stimulus cytoplasm;cytoskeleton nucleotide binding;protein binding Pf00022 11475 ENSMUSG00000035783.8 Acta2 19 Smooth Muscle Contraction Vascular smooth muscle contraction 0 High F6SMY7 E3 ubiquitin-protein ligase MYCBP2 (Fragment) OS=Mus musculus OX=10090 GN=Mycbp2 PE=1 SV=1 0 641.153 38 136 723 136 4636 509 7.09 22 1 9 23 1 9 1402727.146 13985613.69 4040107.044 6846258.46 23 88 49 83 metal ion binding;protein binding "Pf00415, Pf00630, Pf08005, Pf08239, Pf13540, Pf13639, Pf13923" ENSMUSG00000033004.14 14 0 High Q8BMF4 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Mus musculus OX=10090 GN=Dlat PE=1 SV=2" 0 73.504 38 18 107 18 642 67.9 8.57 17 6 6 5 39 10 8 9 37519179.72 5448647.666 5061552.973 4273542.76 18 15 14 15 metabolic process mitochondrion;organelle lumen catalytic activity;protein binding "Pf00198, Pf00364, Pf02817" 235339 ENSMUSG00000000168.9 Dlat 9 Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Glyoxylate metabolism and glycine degradation Pyruvate metabolism; Citrate cycle (TCA cycle); Metabolic pathways; Glycolysis / Gluconeogenesis; Carbon metabolism 0 High Q8K2B3 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Mus musculus OX=10090 GN=Sdha PE=1 SV=1" 0 64.306 42 18 53 18 664 72.5 7.37 16 7 1 9 22 8 1 9 6504023.031 5648800.221 2734814.75 3772594.047 17 15 14 16 metabolic process;transport membrane;mitochondrion catalytic activity;nucleotide binding "Pf00890, Pf02910" 66945 ENSMUSG00000021577.13 Sdha 13 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Carbon metabolism 0 High D3Z041 Long-chain-fatty-acid--CoA ligase 1 OS=Mus musculus OX=10090 GN=Acsl1 PE=1 SV=1 0 41.437 22 12 36 10 699 78 7.47 4 1 6 4 1 9 1354573.604 1677367.992 233655.0352 3306295.359 8 9 4 10 Acetyl [N-Term] metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion catalytic activity Pf00501 ENSMUSG00000018796.13 8 0 High P20152 Vimentin OS=Mus musculus OX=10090 GN=Vim PE=1 SV=3 0 139.773 53 29 227 23 466 53.7 5.12 18 15 3 9 23 20 3 10 10051817.2 10591876.22 4203995.826 5272074.74 28 22 20 25 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane protein binding;RNA binding;structural molecule activity "Pf00038, Pf04111, Pf04156, Pf04732, Pf05622, Pf10186" 22352 ENSMUSG00000026728.9 Vim 2 Striated Muscle Contraction; Caspase-mediated cleavage of cytoskeletal proteins MicroRNAs in cancer; Epstein-Barr virus infection 7 High A2A513 "Keratin, type I cytoskeletal 10 OS=Mus musculus OX=10090 GN=Krt10 PE=1 SV=1" 0 39.652 11 7 160 5 561 57 5.07 3 6 2 6 6 13 2 10 2823831.77 23213683.14 1122854.197 3436923.383 8 8 6 6 cell differentiation;cell organization and biogenesis;metabolic process;response to stimulus cytoplasm;cytoskeleton;membrane;nucleus protein binding;structural molecule activity Pf00038 16661 ENSMUSG00000019761.10 Krt10 11 Formation of the cornified envelope Staphylococcus aureus infection 0 High Q8BFR5 "Elongation factor Tu, mitochondrial OS=Mus musculus OX=10090 GN=Tufm PE=1 SV=1" 0 96.385 62 20 94 20 452 49.5 7.56 3 5 2 6 3 6 3 10 2302874.623 4303259.641 2326902.861 4785818.049 11 9 10 13 metabolic process;response to stimulus membrane;mitochondrion catalytic activity;nucleotide binding;RNA binding "Pf00009, Pf03143, Pf03144" 233870 ENSMUSG00000073838.10 Tufm 7 0 High P16627 Heat shock 70 kDa protein 1-like OS=Mus musculus OX=10090 GN=Hspa1l PE=1 SV=4 0 30.402 11 5 92 2 641 70.6 6.24 2 3 3 2 4 10 cell differentiation;cell organization and biogenesis;development;metabolic process cytosol;mitochondrion;organelle lumen nucleotide binding;protein binding "Pf00012, Pf06723" 15482 ENSMUSG00000007033.4 Hspa1l 17 HSF1-dependent transactivation Endocytosis; MAPK signaling pathway; Toxoplasmosis; Epstein-Barr virus infection; Spliceosome; Legionellosis; Influenza A; Antigen processing and presentation; Protein processing in endoplasmic reticulum; Estrogen signaling pathway; Measles; Longevity regulating pathway - multiple species 0 High Q922R8 Protein disulfide-isomerase A6 OS=Mus musculus OX=10090 GN=Pdia6 PE=1 SV=3 0 100.313 42 16 80 1 440 48.1 5.14 6 10 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytosol;endoplasmic reticulum;membrane;organelle lumen catalytic activity "Pf00085, Pf13098, Pf13848, Pf13899, Pf13905" 71853 Pdia6 12 Protein processing in endoplasmic reticulum 0 High D3Z6B9 Mitochondrial 10-formyltetrahydrofolate dehydrogenase OS=Mus musculus OX=10090 GN=Aldh1l2 PE=1 SV=1 0 26.564 9 7 64 1 810 88.8 5.58 3 2 5 5 2 10 401853.8125 448671.4375 1 1 metabolic process cytoplasm;mitochondrion catalytic activity "Pf00171, Pf00550, Pf00551, Pf02911" 216188 ENSMUSG00000020256.14 Aldh1l2 10 0 High Q91VA7 "Isocitrate dehydrogenase [NAD] subunit, mitochondrial OS=Mus musculus OX=10090 GN=Idh3b PE=1 SV=1" 0 35.877 41 12 43 12 384 42.2 8.6 7 7 1 8 9 9 1 10 5835863.752 4164607.527 2739401.875 5304508.339 12 11 11 12 metabolic process mitochondrion;nucleus catalytic activity;metal ion binding;nucleotide binding Pf00180 170718 ENSMUSG00000027406.12 Idh3b 2 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Biosynthesis of amino acids; 2-Oxocarboxylic acid metabolism; Carbon metabolism 0 High P35486 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Mus musculus OX=10090 GN=Pdha1 PE=1 SV=1" 0 30.839 33 10 35 10 390 43.2 8.19 9 4 1 7 15 7 1 10 4147606.564 1993801.221 622416.7891 1998751.159 9 8 5 10 metabolic process mitochondrion;nucleus;organelle lumen catalytic activity Pf00676 18597 ENSMUSG00000031299.10 Pdha1 X Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Glyoxylate metabolism and glycine degradation Pyruvate metabolism; Citrate cycle (TCA cycle); Metabolic pathways; Glycolysis / Gluconeogenesis; HIF-1 signaling pathway; Carbon metabolism; Central carbon metabolism in cancer; Glucagon signaling pathway 0 High E9PUU4 Gem-associated protein 5 OS=Mus musculus OX=10090 GN=Gemin5 PE=1 SV=1 0 189.619 38 43 220 43 1503 166.6 6.74 13 1 9 16 1 11 245452.8525 7697362.655 3003958.662 4943138.224 8 35 20 33 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;cytosol;membrane;nucleus protein binding;RNA binding Pf00400 216766 ENSMUSG00000037275.14 Gemin5 11 0 High P19096 Fatty acid synthase OS=Mus musculus OX=10090 GN=Fasn PE=1 SV=2 0 192.18 35 60 150 60 2504 272.3 6.58 55 9 4 10 88 9 5 11 35678090.97 6577939.273 6653284.371 8031060.85 58 35 30 43 Acetyl [N-Term] cell differentiation;metabolic process;response to stimulus cytoplasm;cytosol;Golgi;membrane;mitochondrion catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00106, Pf00107, Pf00109, Pf00550, Pf00698, Pf00975, Pf02801, Pf08241, Pf08242, Pf08659, Pf12847, Pf13489, Pf13602, Pf13847, Pf14765" 14104 ENSMUSG00000025153.9 Fasn 11 ChREBP activates metabolic gene expression; Fatty acyl-CoA biosynthesis; Vitamin B5 (pantothenate) metabolism Fatty acid metabolism; Insulin signaling pathway; Metabolic pathways; AMPK signaling pathway; Fatty acid biosynthesis 0 High Q9Z2I9 "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial OS=Mus musculus OX=10090 GN=Sucla2 PE=1 SV=2" 0 37.541 35 13 48 13 463 50.1 7.01 8 6 2 9 10 8 2 11 2866088.5 3243206.469 1010658.414 2621883.148 12 10 9 11 metabolic process mitochondrion catalytic activity;metal ion binding;nucleotide binding "Pf00549, Pf02222, Pf02786, Pf08442, Pf13535, Pf13549" 20916 ENSMUSG00000022110.13 Sucla2 14 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Propanoate metabolism; Carbon metabolism 0 High P70404 "Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial OS=Mus musculus OX=10090 GN=Idh3g PE=1 SV=1" 0 36.765 45 11 37 11 393 42.8 9.01 11 5 9 16 8 11 5539040.549 4162193.848 1498136.172 4529023.086 11 9 7 11 metabolic process;regulation of biological process mitochondrion catalytic activity;metal ion binding;nucleotide binding Pf00180 15929 ENSMUSG00000002010.17 Idh3g X Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Biosynthesis of amino acids; 2-Oxocarboxylic acid metabolism; Carbon metabolism 0 High P63260 "Actin, cytoplasmic 2 OS=Mus musculus OX=10090 GN=Actg1 PE=1 SV=1" 0 644.218 96 37 3199 1 375 41.8 5.48 11 9 2 6 20 16 2 12 947730.3042 883192.6052 123091.855 216682.5601 2 3 2 2 Met-loss+Acetyl [N-Term] cell organization and biogenesis cytoplasm;cytoskeleton;cytosol;membrane;nucleus nucleotide binding;protein binding;structural molecule activity Pf00022 11465 ENSMUSG00000062825.15 Actg1 11 Interaction between L1 and Ankyrins; VEGFA-VEGFR2 Pathway; Adherens junctions interactions; Regulation of actin dynamics for phagocytic cup formation; RHO GTPases activate IQGAPs; Formation of annular gap junctions; RHO GTPases Activate Formins; Recycling pathway of L1; RHO GTPases Activate WASPs and WAVEs; Cell-extracellular matrix interactions; Clathrin-mediated endocytosis; EPHB-mediated forward signaling Oxytocin signaling pathway; Leukocyte transendothelial migration; Hypertrophic cardiomyopathy (HCM); Regulation of actin cytoskeleton; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Focal adhesion; Hippo signaling pathway; Platelet activation; Dilated cardiomyopathy; Adherens junction; Phagosome; Proteoglycans in cancer; Salmonella infection; Thyroid hormone signaling pathway; Rap1 signaling pathway; Influenza A; Viral myocarditis; Tight junction; Bacterial invasion of epithelial cells; Apoptosis 0 High P48962 ADP/ATP translocase 1 OS=Mus musculus OX=10090 GN=Slc25a4 PE=1 SV=4 0 56.252 62 17 114 8 298 32.9 9.72 3 4 1 8 4 4 1 12 201242.3193 293362.5527 237559.6602 1394411.867 6 5 6 9 Met-loss+Acetyl [N-Term] cell organization and biogenesis;regulation of biological process;transport membrane;mitochondrion;nucleus protein binding;transporter activity Pf00153 11739 ENSMUSG00000031633.4 Slc25a4 8 Regulation of insulin secretion HTLV-I infection; Huntington's disease; Parkinson's disease; cGMP-PKG signaling pathway; Calcium signaling pathway 0 High Q9D2G2 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Mus musculus OX=10090 GN=Dlst PE=1 SV=1" 0 27.696 21 8 71 8 454 49 8.95 8 3 1 7 16 5 1 12 6216836.911 4614619.604 2620310.688 2975994.914 8 7 7 7 metabolic process membrane;mitochondrion;nucleus catalytic activity;protein binding "Pf00198, Pf00364" 78920 ENSMUSG00000004789.9 Dlst 12 Lysine catabolism; Citric acid cycle (TCA cycle); Glyoxylate metabolism and glycine degradation Citrate cycle (TCA cycle); Metabolic pathways; Lysine degradation; Carbon metabolism 0 High P60710 "Actin, cytoplasmic 1 OS=Mus musculus OX=10090 GN=Actb PE=1 SV=1" 0 655.12 96 38 3346 2 375 41.7 5.48 12 10 2 7 23 17 2 13 14812502.31 11467067.69 7299405.24 9813521.182 37 32 30 32 Met-loss+Acetyl [N-Term]; Acetyl [N-Term] cell organization and biogenesis;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;nucleus DNA binding;nucleotide binding;protein binding Pf00022 11461 ENSMUSG00000029580.14 Actb 5 Interaction between L1 and Ankyrins; DNA Damage Recognition in GG-NER; VEGFA-VEGFR2 Pathway; Adherens junctions interactions; UCH proteinases; Regulation of actin dynamics for phagocytic cup formation; B-WICH complex positively regulates rRNA expression; RHO GTPases activate IQGAPs; Formation of annular gap junctions; RHO GTPases Activate Formins; Recycling pathway of L1; RHO GTPases Activate WASPs and WAVEs; Cell-extracellular matrix interactions; Clathrin-mediated endocytosis; EPHB-mediated forward signaling Oxytocin signaling pathway; Leukocyte transendothelial migration; Hypertrophic cardiomyopathy (HCM); Regulation of actin cytoskeleton; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Focal adhesion; Hippo signaling pathway; Platelet activation; Dilated cardiomyopathy; Adherens junction; Phagosome; Proteoglycans in cancer; Salmonella infection; Thyroid hormone signaling pathway; Rap1 signaling pathway; Influenza A; Viral myocarditis; Tight junction; Gastric acid secretion; Bacterial invasion of epithelial cells; Apoptosis 63 High Q3U3J1 2-oxoisovalerate dehydrogenase subunit alpha OS=Mus musculus OX=10090 GN=Bckdha PE=1 SV=1 0 263.18 69 27 260 27 446 50.7 8.06 14 8 2 8 26 9 2 13 10884144.12 6669243.229 1822232.372 6648863.969 24 18 10 20 metabolic process mitochondrion catalytic activity;metal ion binding;protein binding "Pf00456, Pf00676" 12039 ENSMUSG00000060376.7 Bckdha 7 Glyoxylate metabolism and glycine degradation; Branched-chain amino acid catabolism "Valine, leucine and isoleucine degradation; Metabolic pathways; Propanoate metabolism" 0 High P53395 "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial OS=Mus musculus OX=10090 GN=Dbt PE=1 SV=2" 0 148.775 72 29 211 29 482 53.2 8.6 12 6 3 6 20 8 3 13 11080379.35 6662584.16 4725170.805 6898792.099 22 13 13 17 metabolic process mitochondrion;organelle lumen catalytic activity;protein binding "Pf00198, Pf00364, Pf02817" 13171 ENSMUSG00000000340.10 Dbt 3 Glyoxylate metabolism and glycine degradation; Branched-chain amino acid catabolism "Valine, leucine and isoleucine degradation; Metabolic pathways; Propanoate metabolism" 0 High Q3TML0 Protein disulfide-isomerase A6 OS=Mus musculus OX=10090 GN=Pdia6 PE=1 SV=1 0 103.098 42 16 86 1 445 48.7 5.19 1 7 1 13 268292.8882 534286.9502 8841.603516 3566308.066 7 8 1 13 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytosol;endoplasmic reticulum;membrane;organelle lumen catalytic activity "Pf00085, Pf13098, Pf13848, Pf13899, Pf13905" 71853 ENSMUSG00000020571.12 Pdia6 12 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation Protein processing in endoplasmic reticulum 14 High P11152 Lipoprotein lipase OS=Mus musculus OX=10090 GN=Lpl PE=1 SV=3 0 28.546 28 9 15 9 474 53.1 7.87 1 9 1 13 6238.041016 326750.3809 179169.8125 7675922.375 1 1 1 8 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cell surface;extracellular;membrane catalytic activity;protein binding "Pf00151, Pf01477, Pf12695, Pf12697" 16956 ENSMUSG00000015568.16 Lpl 8 Assembly of active LPL and LIPC lipase complexes; Chylomicron remodeling; Signaling by GPCR; Retinoid metabolism and transport PPAR signaling pathway; Alzheimer's disease; Glycerolipid metabolism 0 High P63017 Heat shock cognate 71 kDa protein OS=Mus musculus OX=10090 GN=Hspa8 PE=1 SV=1 0 248.413 53 31 559 27 646 70.8 5.52 9 6 7 9 8 14 4282886.704 3627611.18 1424455.504 3363126.829 25 22 13 23 cell organization and biogenesis;metabolic process;regulation of biological process;transport cell surface;cytoplasm;cytosol;endosome;membrane;nucleus;spliceosomal complex;vacuole catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00012, Pf02463, Pf06723" 15481 ENSMUSG00000015656.17 Hspa8 9 "Regulation of HSF1-mediated heat shock response; Golgi Associated Vesicle Biogenesis; mRNA Splicing - Major Pathway; Attenuation phase; Neutrophil degranulation; AUF1 (hnRNP D0) binds and destabilizes mRNA; GABA synthesis, release, reuptake and degradation; HSP90 chaperone cycle for steroid hormone receptors (SHR); Protein methylation; Clathrin-mediated endocytosis" Endocytosis; MAPK signaling pathway; Toxoplasmosis; Epstein-Barr virus infection; Spliceosome; Legionellosis; Influenza A; Antigen processing and presentation; Protein processing in endoplasmic reticulum; Estrogen signaling pathway; Measles; Longevity regulating pathway - multiple species 1 High P16858 Glyceraldehyde-3-phosphate dehydrogenase OS=Mus musculus OX=10090 GN=Gapdh PE=1 SV=2 0 179.273 74 21 340 21 333 35.8 8.25 10 5 2 9 14 7 2 15 8021748.647 6898026.251 2641130.499 7128780.214 26 17 11 24 Met-loss [N-Term] cell death;cell organization and biogenesis;defense response;development;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;mitochondrion;nucleus catalytic activity;enzyme regulator activity;nucleotide binding;protein binding "Pf00044, Pf02800" 14433; 100042025; 100042746 ENSMUSG00000057666.18 Gapdh; Gm20899; LOC100042025; Gapdh-ps15; Gm12033 6; Y; 11 Metabolic pathways; Biosynthesis of amino acids; Glycolysis / Gluconeogenesis; HIF-1 signaling pathway; Alzheimer's disease; Carbon metabolism 0 High P50544 "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Acadvl PE=1 SV=3" 0 78.868 38 18 83 18 656 70.8 8.75 14 10 4 11 25 17 5 15 7762908.837 6348431.188 5137822.869 5635610.426 18 15 15 18 cell differentiation;metabolic process;regulation of biological process;response to stimulus cytosol;membrane;mitochondrion;nucleus catalytic activity;nucleotide binding "Pf00441, Pf02770, Pf02771, Pf08028" 11370 ENSMUSG00000018574.14 Acadvl 11 Beta oxidation of palmitoyl-CoA to myristoyl-CoA Fatty acid metabolism; Metabolic pathways; Fatty acid degradation 0 High Q8CAQ8 MICOS complex subunit Mic60 OS=Mus musculus OX=10090 GN=Immt PE=1 SV=1 0 63.388 26 17 61 17 757 83.8 6.61 1 3 3 11 1 4 3 15 1376017.801 2006511.041 1556884.555 4291065.516 15 13 12 16 cell organization and biogenesis;cellular homeostasis membrane;mitochondrion protein binding;RNA binding Pf09731 76614 ENSMUSG00000052337.15 Immt 6 0 High P21981 Protein-glutamine gamma-glutamyltransferase 2 OS=Mus musculus OX=10090 GN=Tgm2 PE=1 SV=4 0 109.342 42 21 150 21 686 77 5.1 14 12 2 9 26 22 3 16 15837688.69 15650762.27 4015492.82 4872369.485 19 17 13 16 Met-loss+Acetyl [N-Term] cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;endoplasmic reticulum;membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00868, Pf00927, Pf01841" 21817 ENSMUSG00000037820.15 Tgm2 2 Huntington's disease 0 High Q8BWT1 "3-ketoacyl-CoA thiolase, mitochondrial OS=Mus musculus OX=10090 GN=Acaa2 PE=1 SV=3" 0 197.707 73 24 279 24 397 41.8 8.09 18 14 10 10 34 21 17 18 35052900.26 17445490.77 12428536.4 17110670.13 25 24 19 24 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion;organelle lumen catalytic activity;RNA binding "Pf00108, Pf02801, Pf02803" 52538 ENSMUSG00000036880.9 Acaa2 18 Mitochondrial Fatty Acid Beta-Oxidation "Fatty acid metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Fatty acid degradation; Fatty acid elongation" 0 High E9PUQ5 Golgin subfamily A member 2 OS=Mus musculus OX=10090 GN=Golga2 PE=1 SV=1 0 300.745 59 46 383 46 1026 116.2 5.05 1 15 1 10 1 22 1 19 2036514.478 19703808.81 2734527.001 13845722.63 7 32 17 40 cell division;cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;Golgi;membrane;nucleus protein binding "Pf12128, Pf15070" 99412 ENSMUSG00000002546.16 Golga2 2 0 High P19324 Serpin H1 OS=Mus musculus OX=10090 GN=Serpinh1 PE=1 SV=3 0 46.636 38 12 31 12 417 46.5 8.82 12 20 237579.1858 626784.5166 127897.5605 4701875.984 7 6 4 12 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;endoplasmic reticulum;membrane;organelle lumen enzyme regulator activity;protein binding;RNA binding Pf00079 12406 ENSMUSG00000070436.12 Serpinh1 7 Collagen biosynthesis and modifying enzymes 0 High A0A1Y7VJN6 Immunoglobulin heavy constant gamma 3 (Fragment) OS=Mus musculus OX=10090 GN=Ighg3 PE=4 SV=1 0 87.605 45 14 244 14 399 44 7.14 12 11 2 7 39 34 4 21 30627829.02 26912093.63 9665693.141 8954876.048 19 19 13 16 membrane "Pf07654, Pf08205" 0 High P51881 ADP/ATP translocase 2 OS=Mus musculus OX=10090 GN=Slc25a5 PE=1 SV=3 0 63.934 70 18 141 9 298 32.9 9.73 4 6 1 11 5 6 1 21 2606036.027 7467480.33 1778201.125 17370085.68 13 13 8 18 Met-loss+Acetyl [N-Term] cell organization and biogenesis;regulation of biological process;transport membrane;mitochondrion;nucleus protein binding;RNA binding;transporter activity Pf00153 11740 ENSMUSG00000016319.3 Slc25a5 X Regulation of insulin secretion HTLV-I infection; Huntington's disease; Parkinson's disease; cGMP-PKG signaling pathway; Calcium signaling pathway 10 High Q60597 "2-oxoglutarate dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Ogdh PE=1 SV=3" 0 102.556 42 30 103 25 1023 116.4 6.83 28 16 16 47 21 23 32897987.19 16437679.77 5012416.203 10991939.82 32 24 19 30 cellular component movement;metabolic process cytosol;membrane;mitochondrion;organelle lumen catalytic activity;metal ion binding;protein binding "Pf00676, Pf02779" 18293 ENSMUSG00000020456.17 Ogdh 11 Lysine catabolism; Citric acid cycle (TCA cycle); Glyoxylate metabolism and glycine degradation Tryptophan metabolism; Citrate cycle (TCA cycle); Metabolic pathways; Lysine degradation; Carbon metabolism 5 High P38647 "Stress-70 protein, mitochondrial OS=Mus musculus OX=10090 GN=Hspa9 PE=1 SV=3" 0 190.593 51 34 336 33 679 73.4 6.07 14 17 7 14 18 26 8 24 10964268.64 11348558.46 7343860.948 9475014.027 34 27 24 30 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;mitochondrion;nucleus;organelle lumen nucleotide binding;protein binding;RNA binding "Pf00012, Pf06723" 15526 ENSMUSG00000024359.8 Hspa9 18 RNA degradation; Tuberculosis 1 High Q5SWU9 Acetyl-CoA carboxylase 1 OS=Mus musculus OX=10090 GN=Acaca PE=1 SV=1 0 152.663 28 48 198 48 2345 265.1 6.39 2 21 6 23 3 24 6 24 2281642.014 8672814.495 5899342.795 7363102.359 34 45 32 45 Acetyl [N-Term] cell organization and biogenesis;metabolic process;response to stimulus cytoplasm;cytoskeleton;cytosol;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00289, Pf00364, Pf01039, Pf02222, Pf02655, Pf02785, Pf02786, Pf07478, Pf08326, Pf13535, Pf15632" 107476 ENSMUSG00000020532.18 Acaca 11 ChREBP activates metabolic gene expression; Biotin transport and metabolism; Fatty acyl-CoA biosynthesis; Import of palmitoyl-CoA into the mitochondrial matrix Fatty acid metabolism; Pyruvate metabolism; Insulin signaling pathway; Metabolic pathways; Propanoate metabolism; AMPK signaling pathway; Fatty acid biosynthesis; Glucagon signaling pathway 0 High A0A075B5P6 Immunoglobulin heavy constant mu (Fragment) OS=Mus musculus OX=10090 GN=Ighm PE=1 SV=1 0 122.373 47 20 349 20 455 50 7.01 16 11 7 10 52 32 12 26 48684920.94 23438994.28 11575518.42 10966533.43 22 18 16 18 "Pf07654, Pf07679" ENSMUSG00000076617.9 12 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Cell surface interactions at the vascular wall; CD22 mediated BCR regulation 0 High Q924X2 "Carnitine O-palmitoyltransferase 1, muscle isoform OS=Mus musculus OX=10090 GN=Cpt1b PE=1 SV=1" 0 38.731 23 15 47 14 772 88.2 8.38 9 5 1 14 11 6 1 26 2567125.926 2173156.51 822133.6143 6607704.378 14 11 8 14 metabolic process;transport membrane;mitochondrion catalytic activity Pf00755 12895 ENSMUSG00000078937.8 Cpt1b 15 Signaling by Retinoic Acid; Import of palmitoyl-CoA into the mitochondrial matrix PPAR signaling pathway; Fatty acid metabolism; Fatty acid degradation; Insulin resistance; Adipocytokine signaling pathway; AMPK signaling pathway; Glucagon signaling pathway 1 High F6Z458 Endoplasmic reticulum lectin 1 (Fragment) OS=Mus musculus OX=10090 GN=Erlec1 PE=1 SV=1 0 226.79 81 17 370 2 238 27.3 7.49 1 10 3 27 6677.845703 1 "Pf07915, Pf13015" ENSMUSG00000020311.17 11 0 High Q99JY0 "Trifunctional enzyme subunit beta, mitochondrial OS=Mus musculus OX=10090 GN=Hadhb PE=1 SV=1" 0 125.267 63 26 203 26 475 51.4 9.38 19 17 7 21 27 25 9 31 13547696.64 14329691.94 10238068.35 13146838.23 26 26 23 27 metabolic process endoplasmic reticulum;membrane;mitochondrion catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00108, Pf00109, Pf02803" 231086 ENSMUSG00000059447.13 Hadhb 5 Beta oxidation of myristoyl-CoA to lauroyl-CoA; Acyl chain remodeling of CL; Beta oxidation of palmitoyl-CoA to myristoyl-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA "Fatty acid metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Fatty acid degradation; Fatty acid elongation" 0 High P01837 Immunoglobulin kappa constant OS=Mus musculus OX=10090 GN=Igkc PE=1 SV=2 0 192.028 89 11 1099 11 107 11.9 5.9 9 9 5 6 180 102 11 32 219716216.1 130879895.5 50194658.87 32206821.4 21 20 16 18 0 High A0A0A6YVP0 Immunoglobulin heavy constant gamma 2B (Fragment) OS=Mus musculus OX=10090 GN=Ighg2b PE=1 SV=2 0 177.847 41 14 559 13 405 44.3 6.52 13 10 3 7 98 56 14 33 212893761.2 128900346.4 22190820.71 31771193.09 16 15 10 14 membrane "Pf07654, Pf08205" 2 High Q99KI0 "Aconitate hydratase, mitochondrial OS=Mus musculus OX=10090 GN=Aco2 PE=1 SV=1" 0 101.478 44 25 139 25 780 85.4 7.93 25 17 10 19 48 37 14 35 18504988.27 32245139.98 13486199.06 11201349.09 24 23 24 24 metabolic process;response to stimulus mitochondrion catalytic activity;metal ion binding "Pf00330, Pf00694" 11429 ENSMUSG00000022477.12 Aco2 15 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Biosynthesis of amino acids; 2-Oxocarboxylic acid metabolism; Carbon metabolism; Glyoxylate and dicarboxylate metabolism 0 High Q8BMS1 "Trifunctional enzyme subunit alpha, mitochondrial OS=Mus musculus OX=10090 GN=Hadha PE=1 SV=1" 0 218.633 64 34 339 34 763 82.6 9.14 24 21 7 21 39 33 9 37 25185059.46 19215448.18 16422962.9 23006812.98 37 34 27 36 metabolic process;response to stimulus membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding;protein binding "Pf00378, Pf00725, Pf02737" 97212 ENSMUSG00000025745.11 Hadha 5 Beta oxidation of myristoyl-CoA to lauroyl-CoA; Acyl chain remodeling of CL; Beta oxidation of palmitoyl-CoA to myristoyl-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA "Fatty acid metabolism; Tryptophan metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Lysine degradation; Fatty acid degradation; Butanoate metabolism; beta-Alanine metabolism; Propanoate metabolism; Fatty acid elongation; Carbon metabolism; Biosynthesis of unsaturated fatty acids" 0 High Q8VEH8 Endoplasmic reticulum lectin 1 OS=Mus musculus OX=10090 GN=Erlec1 PE=1 SV=1 0 453.732 80 32 771 17 483 54.9 6.25 2 19 4 51 576581.3428 2878446.979 2995190.384 33249808.48 12 13 16 35 metabolic process;transport endoplasmic reticulum;organelle lumen protein binding "Pf07915, Pf13015" 66753 ENSMUSG00000020311.17 Erlec1 11 Hedgehog ligand biogenesis; ABC-family proteins mediated transport Protein processing in endoplasmic reticulum 16 High Q8K010 5-oxoprolinase OS=Mus musculus OX=10090 GN=Oplah PE=1 SV=1 0 187.263 40 38 195 38 1288 137.5 6.28 30 9 34 49 10 57 5413054.609 21268383.66 10108338.04 21521626.74 21 32 31 35 metabolic process cytosol catalytic activity;nucleotide binding "Pf01968, Pf02538, Pf05378" 75475 ENSMUSG00000022562.14 Oplah 15 Glutathione synthesis and recycling Glutathione metabolism 0 High F8VPN4 "Amylo-1,6-glucosidase, 4-alpha-glucanotransferase OS=Mus musculus OX=10090 GN=Agl PE=1 SV=1" 0 551.781 69 80 1032 80 1532 174.2 6.74 44 40 13 40 62 60 13 58 40501491.57 43127637.23 21578587.88 29722820.2 79 72 60 76 metabolic process;response to stimulus cytoplasm;endoplasmic reticulum;nucleus catalytic activity;protein binding "Pf00128, Pf06202, Pf14699, Pf14701, Pf14702" 77559 ENSMUSG00000033400.14 Agl 3 Glycogen breakdown (glycogenolysis); Neutrophil degranulation Metabolic pathways; Starch and sucrose metabolism 0 High Q9Z2G6 Protein sel-1 homolog 1 OS=Mus musculus OX=10090 GN=Sel1l PE=1 SV=2 0 710.717 70 44 1575 44 790 88.3 5.57 8 4 22 12 4 90 4930825.326 11628013.46 8863649.793 132630283.7 32 36 30 66 metabolic process;regulation of biological process;response to stimulus;transport endoplasmic reticulum;membrane protein binding "Pf00040, Pf08238" 20338 ENSMUSG00000020964.14 Sel1l 12 Hedgehog ligand biogenesis; ABC-family proteins mediated transport; ER Quality Control Compartment (ERQC) Protein processing in endoplasmic reticulum 0 High Q8K2C7 Protein OS-9 OS=Mus musculus OX=10090 GN=Os9 PE=1 SV=2 0 680.772 80 61 1252 61 672 76.1 4.84 1 33 1 100 1644572.258 2168006.617 2425028.866 105043107.5 14 19 17 67 metabolic process;response to stimulus;transport endoplasmic reticulum;organelle lumen protein binding "Pf07915, Pf13015" 216440 ENSMUSG00000040462.13 Os9 10 Hedgehog ligand biogenesis; ABC-family proteins mediated transport; ER Quality Control Compartment (ERQC) Protein processing in endoplasmic reticulum 0 High Q8R0Y6 Cytosolic 10-formyltetrahydrofolate dehydrogenase OS=Mus musculus OX=10090 GN=Aldh1l1 PE=1 SV=1 0 649.101 91 78 961 72 902 98.6 5.91 44 26 52 90 38 120 1722466.448 99102441.49 70708230.76 105100091.1 14 76 74 82 Met-loss [N-Term] metabolic process cytoplasm;cytosol;mitochondrion catalytic activity;protein binding "Pf00171, Pf00550, Pf00551, Pf02911" 107747 ENSMUSG00000030088.15 Aldh1l1 6 Metabolism of folate and pterines One carbon pool by folate 6 High P08113 Endoplasmin OS=Mus musculus OX=10090 GN=Hsp90b1 PE=1 SV=2 0 621.717 69 63 1309 61 802 92.4 4.82 5 40 5 149 1276102.884 4127611.461 324514.269 161330349.1 25 29 8 72 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytosol;endoplasmic reticulum;extracellular;membrane;nucleus;organelle lumen nucleotide binding;protein binding;RNA binding "Pf00183, Pf02518, Pf13589" 22027 ENSMUSG00000020048.13 Hsp90b1 10 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Scavenging by Class A Receptors; Trafficking and processing of endosomal TLR Thyroid hormone synthesis; Pathways in cancer; PI3K-Akt signaling pathway; Protein processing in endoplasmic reticulum; Estrogen signaling pathway; Prostate cancer 4 High P20029 Endoplasmic reticulum chaperone BiP OS=Mus musculus OX=10090 GN=Hspa5 PE=1 SV=3 0 631.384 73 57 1723 55 655 72.4 5.16 3 20 39 3 40 226 3197106.094 41037770.63 1710561.697 498841290.9 37 43 14 67 cell communication;cell death;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;endoplasmic reticulum;extracellular;membrane;mitochondrion;nucleus;organelle lumen catalytic activity;nucleotide binding;protein binding "Pf00012, Pf01968, Pf06723" 14828 ENSMUSG00000026864.13 Hspa5 2 Thyroid hormone synthesis; Antigen processing and presentation; Protein export; Prion diseases; Protein processing in endoplasmic reticulum 3 High Q8VDD5 Myosin-9 OS=Mus musculus OX=10090 GN=Myh9 PE=1 SV=4 0 2596.388 75 213 4596 176 1960 226.2 5.66 8097576.288 4943168.222 6175489.581 5949476.295 87 46 31 54 Met-loss+Acetyl [N-Term] cell differentiation;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;cytosol;extracellular;membrane;nucleus catalytic activity;motor activity;nucleotide binding;protein binding;RNA binding;transporter activity "Pf00063, Pf01442, Pf01496, Pf01576, Pf01765, Pf02463, Pf02736, Pf03962, Pf04111, Pf04156, Pf05667, Pf05911, Pf06160, Pf06637, Pf07111, Pf07888, Pf08317, Pf09726, Pf09731, Pf10498, Pf11559, Pf11917, Pf12128, Pf13094, Pf13166" 17886 ENSMUSG00000022443.16 Myh9 15 RHO GTPases activate PAKs Regulation of actin cytoskeleton; Tight junction 49 High Q68FD5 Clathrin heavy chain 1 OS=Mus musculus OX=10090 GN=Cltc PE=1 SV=3 0 1374.552 80 128 1854 128 1675 191.4 5.69 157167586.5 146102571.9 141933300.3 79979606.83 51 42 22 34 Met-loss+Acetyl [N-Term] cell differentiation;cell division;cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;cytosol;endosome;membrane;mitochondrion;vacuole protein binding;RNA binding;structural molecule activity "Pf00637, Pf01394, Pf04053, Pf09268, Pf13838" 67300 ENSMUSG00000047126.17 Cltc 11 "WNT5A-dependent internalization of FZD4; Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis; VLDLR internalisation and degradation; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Recycling pathway of L1; MHC class II antigen presentation; Cargo recognition for clathrin-mediated endocytosis; LDL clearance" Endocytosis; Endocrine and other factor-regulated calcium reabsorption; Lysosome; Huntington's disease; Synaptic vesicle cycle; Bacterial invasion of epithelial cells 0 High Q3UH59 Myosin-10 OS=Mus musculus OX=10090 GN=Myh10 PE=1 SV=1 0 1070.404 60 134 1122 99 2013 233.3 5.57 2980543.61 2080922.343 1104295.067 1029916.261 28 15 7 16 cell organization and biogenesis;cell proliferation;cellular component movement;metabolic process;regulation of biological process;transport cytoplasm;extracellular;membrane;nucleus catalytic activity;motor activity;nucleotide binding;protein binding;transporter activity "Pf00063, Pf00769, Pf01442, Pf01496, Pf01576, Pf02736, Pf02841, Pf04012, Pf04111, Pf05622, Pf05667, Pf05911, Pf06637, Pf07888, Pf09726, Pf09731, Pf12128, Pf13094, Pf13514" 77579 ENSMUSG00000020900.15 Myh10 11 Regulation of actin cytoskeleton; Tight junction 2 High E9QPE7 Myosin-11 OS=Mus musculus OX=10090 GN=Myh11 PE=1 SV=2 0 980.463 62 144 940 7 1972 227 5.48 1780378.808 1650586.76 414969.3457 738355.9114 41 21 8 22 120 High O08638 Myosin-11 OS=Mus musculus OX=10090 GN=Myh11 PE=1 SV=1 0 883.474 59 134 869 1 1972 226.9 5.45 411548.7813 255557.6406 1 1 cell differentiation;cell organization and biogenesis;metabolic process;transport cytoplasm;extracellular catalytic activity;motor activity;nucleotide binding;protein binding;structural molecule activity "Pf00038, Pf00063, Pf01442, Pf01576, Pf02463, Pf02736, Pf04111, Pf04156, Pf07111, Pf07888, Pf09726, Pf09731, Pf10079, Pf12128, Pf12252, Pf13166" 17880 Myh11 16 0 High P16546 "Spectrin alpha chain, non-erythrocytic 1 OS=Mus musculus OX=10090 GN=Sptan1 PE=1 SV=4" 0 1066.818 68 157 817 2 2472 284.4 5.33 19075397.6 13252158.31 9002485.059 7107339.521 71 34 22 32 cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton;membrane metal ion binding;protein binding "Pf00018, Pf00036, Pf00435, Pf07653, Pf08239, Pf08726, Pf12128, Pf13405, Pf13499, Pf14604" 20740 ENSMUSG00000057738.13 Spna2; Sptan1 2 NCAM signaling for neurite out-growth; Interaction between L1 and Ankyrins; COPI-mediated anterograde transport; Neutrophil degranulation; Interleukin-20 family signaling; RAF/MAP kinase cascade; Caspase-mediated cleavage of cytoskeletal proteins 161 High E9Q447 "Spectrin alpha chain, non-erythrocytic 1 OS=Mus musculus OX=10090 GN=Sptan1 PE=1 SV=1" 0 1056.765 68 157 816 2 2478 285.2 5.34 10728.48633 1 cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton;membrane metal ion binding;protein binding "Pf00018, Pf00036, Pf00435, Pf07653, Pf08239, Pf08726, Pf12128, Pf13405, Pf13499, Pf14604" 20740 ENSMUSG00000057738.13 Spna2; Sptan1 2 0 High P16460 Argininosuccinate synthase OS=Mus musculus OX=10090 GN=Ass1 PE=1 SV=1 0 379.26 84 37 804 37 412 46.6 8.22 1930159.124 2209433.529 2692306.063 719652.3033 19 15 14 15 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;endoplasmic reticulum;membrane;mitochondrion;nucleus;vacuole catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00764, Pf03054, Pf06508" 11898 ENSMUSG00000076441.9 Ass1 2 Urea cycle "Metabolic pathways; Biosynthesis of amino acids; Alanine, aspartate and glutamate metabolism; Arginine biosynthesis" 0 High P08032 "Spectrin alpha chain, erythrocytic 1 OS=Mus musculus OX=10090 GN=Spta1 PE=1 SV=3" 0 1102.999 75 158 765 157 2415 279.7 5.03 7242798.037 6666042.509 2443657.643 2935432.765 45 22 14 26 Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;cytoskeleton;membrane metal ion binding;protein binding "Pf00018, Pf00435, Pf07653, Pf08726, Pf14604" 20739 ENSMUSG00000026532.7 Spna1; Spta1 1 RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Interaction between L1 and Ankyrins; COPI-mediated anterograde transport; Interleukin-20 family signaling Apoptosis 1 High Q8C196 "Carbamoyl-phosphate synthase [ammonia], mitochondrial OS=Mus musculus OX=10090 GN=Cps1 PE=1 SV=2" 0 570.241 67 81 666 78 1500 164.5 6.92 570802.7317 450242.1177 545538.7734 508337.9163 23 13 7 17 cell differentiation;metabolic process;response to stimulus cytoplasm;membrane;mitochondrion;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00117, Pf00289, Pf00988, Pf02142, Pf02222, Pf02786, Pf02787, Pf07478, Pf13535, Pf15632" 227231 ENSMUSG00000025991.8 Cps1 1 Urea cycle "Metabolic pathways; Nitrogen metabolism; Biosynthesis of amino acids; Carbon metabolism; Alanine, aspartate and glutamate metabolism; Arginine biosynthesis" 3 High Q6URW6 Myosin-14 OS=Mus musculus OX=10090 GN=Myh14 PE=1 SV=1 0 740.597 57 115 639 98 2000 228.4 5.55 498404.3242 212796.5542 428297.334 184182.2974 18 10 3 4 Met-loss+Acetyl [N-Term] cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus cytoplasm;membrane catalytic activity;motor activity;nucleotide binding;protein binding "Pf00063, Pf01576, Pf09726" 71960 ENSMUSG00000030739.18 Myh14 7 RHO GTPases activate PAKs Regulation of actin cytoskeleton; Tight junction 0 High Q3UGX2 Spectrin beta chain OS=Mus musculus OX=10090 GN=Sptb PE=1 SV=1 0 811.3 61 129 631 121 2329 267.9 5.49 45208532.51 33985872.68 18095151.62 18400482.04 32 18 11 22 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process cell surface;cytoplasm;cytoskeleton;cytosol;Golgi;membrane protein binding;structural molecule activity "Pf00169, Pf00307, Pf00435, Pf11971, Pf13514, Pf15410" 20741 ENSMUSG00000021061.15 Spnb1; Sptb 12 RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Interaction between L1 and Ankyrins; COPI-mediated anterograde transport; Interleukin-20 family signaling 8 High E9PVU0 Unconventional myosin-VI OS=Mus musculus OX=10090 GN=Myo6 PE=1 SV=1 0 580.789 71 80 585 2 1266 146.2 8.47 14705.85791 17621.74609 1 1 Acetyl [N-Term] catalytic activity;motor activity;nucleotide binding Pf00063 ENSMUSG00000033577.18 9 Trafficking of AMPA receptors; Gap junction degradation 0 High V9GX76 Unconventional myosin-VI OS=Mus musculus OX=10090 GN=Myo6 PE=1 SV=1 0 574.19 70 80 569 2 1294 149.1 8.46 894904.9247 771281.1544 306778.5674 674239.9072 22 12 7 15 Acetyl [N-Term] cell communication;cell differentiation;cell organization and biogenesis;regulation of biological process;response to stimulus;transport cytoplasm;Golgi;membrane;nucleus catalytic activity;motor activity;nucleotide binding;protein binding Pf00063 17920 ENSMUSG00000033577.18 Myo6 9 Trafficking of AMPA receptors; Gap junction degradation 89 High Q62261 "Spectrin beta chain, non-erythrocytic 1 OS=Mus musculus OX=10090 GN=Sptbn1 PE=1 SV=2" 0 713.962 59 121 538 108 2363 274.1 5.58 3150488.532 1786557.548 956142.2031 2008243.532 49 26 12 31 cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;membrane;nucleus protein binding;RNA binding;structural molecule activity "Pf00169, Pf00307, Pf00435, Pf11971, Pf12128, Pf15410" 20742 ENSMUSG00000020315.18 Spnb2; Sptbn1 11 RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Interaction between L1 and Ankyrins; COPI-mediated anterograde transport; Interleukin-20 family signaling Tight junction 4 High Q9DBG3 AP-2 complex subunit beta OS=Mus musculus OX=10090 GN=Ap2b1 PE=1 SV=1 0 427.793 73 68 515 39 937 104.5 5.38 1909237.474 1783150.145 1036892.542 1068037.196 25 23 18 20 cell organization and biogenesis;transport membrane protein binding;transporter activity "Pf01602, Pf02883, Pf09066, Pf12717, Pf13646" 71770 ENSMUSG00000035152.14 Ap2b1 11 "WNT5A-dependent internalization of FZD4; Trafficking of GluR2-containing AMPA receptors; VLDLR internalisation and degradation; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Recycling pathway of L1; MHC class II antigen presentation; Cargo recognition for clathrin-mediated endocytosis; LDL clearance" Endocytosis; Endocrine and other factor-regulated calcium reabsorption; Huntington's disease; Synaptic vesicle cycle 33 High Q9WTI7 Unconventional myosin-Ic OS=Mus musculus OX=10090 GN=Myo1c PE=1 SV=2 0 401.221 63 64 496 64 1063 121.9 9.35 709331.8506 304471.015 74890.9375 689968.7317 18 10 2 14 Met-loss+Acetyl [N-Term] cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;membrane;nucleus catalytic activity;motor activity;nucleotide binding;protein binding "Pf00063, Pf06017" 17913 ENSMUSG00000017774.19 Myo1c 11 Regulation of actin dynamics for phagocytic cup formation; B-WICH complex positively regulates rRNA expression 0 High K3W4L0 Unconventional myosin-XVIIIa OS=Mus musculus OX=10090 GN=Myo18a PE=1 SV=1 0 582.136 56 103 476 103 2036 230.8 6.19 1244083.284 1699154.195 291512.3271 635470.9219 22 13 6 13 cell differentiation;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;Golgi catalytic activity;motor activity;nucleotide binding;protein binding;structural molecule activity;transporter activity "Pf00038, Pf00063, Pf00595, Pf00769, Pf01496, Pf01576, Pf02463, Pf02841, Pf03962, Pf04111, Pf04156, Pf04502, Pf05483, Pf05557, Pf05622, Pf05667, Pf05701, Pf05911, Pf06160, Pf07111, Pf07888, Pf08286, Pf09726, Pf09728, Pf09730, Pf09755, Pf09787, Pf10174, Pf12128, Pf12329, Pf13166, Pf13514, Pf13851, Pf15070, Pf15397" ENSMUSG00000000631.20 11 0 High Q68FG2 Spectrin beta chain OS=Mus musculus OX=10090 GN=Sptbn2 PE=1 SV=1 0 668.315 56 105 473 94 2388 270.8 5.86 697587.9958 873727.7432 534857.7148 881088.2935 28 12 7 16 cell organization and biogenesis;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;endosome;membrane protein binding;structural molecule activity "Pf00169, Pf00307, Pf00435, Pf11971, Pf15410" 20743 ENSMUSG00000067889.4 Spnb3; Sptbn2 19 RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Interaction between L1 and Ankyrins; COPI-mediated anterograde transport; MHC class II antigen presentation; Interleukin-20 family signaling 2 High P46735 Unconventional myosin-Ib OS=Mus musculus OX=10090 GN=Myo1b PE=1 SV=3 0 473.477 57 66 472 2 1107 128.5 9.26 695810.533 783025.0801 939332.4219 306690.4036 11 8 7 11 cell organization and biogenesis;cellular component movement;transport cytoplasm;endosome;membrane catalytic activity;motor activity;nucleotide binding;protein binding "Pf00063, Pf06017" 17912 ENSMUSG00000018417.14 Myo1b 1 72 High E9QNH6 Unconventional myosin-Ib OS=Mus musculus OX=10090 GN=Myo1b PE=1 SV=1 0 452.565 59 65 455 1 1078 125 9.14 4811.731934 1 cell organization and biogenesis;cellular component movement;transport cytoplasm;endosome;membrane catalytic activity;motor activity;nucleotide binding;protein binding "Pf00063, Pf06017" 17912 ENSMUSG00000018417.14 Myo1b 1 0 High P17427 AP-2 complex subunit alpha-2 OS=Mus musculus OX=10090 GN=Ap2a2 PE=1 SV=2 0 376.579 62 51 448 38 938 104 6.93 987402.5415 493202.9521 757038.9746 374284.5601 14 8 6 13 regulation of biological process;transport Golgi;membrane protein binding;transporter activity "Pf01602, Pf02296, Pf02883, Pf13646" 11772 ENSMUSG00000002957.11 Ap2a2 7 "WNT5A-dependent internalization of FZD4; Trafficking of GluR2-containing AMPA receptors; Neutrophil degranulation; VLDLR internalisation and degradation; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Recycling pathway of L1; MHC class II antigen presentation; Cargo recognition for clathrin-mediated endocytosis; LDL clearance" Endocytosis; Endocrine and other factor-regulated calcium reabsorption; Huntington's disease; Synaptic vesicle cycle 15 High A0A1W2P6G5 Myosin light polypeptide 6 OS=Mus musculus OX=10090 GN=Myl6 PE=1 SV=1 0 169.753 82 10 426 1 139 15.4 4.54 35488.63135 34541.7998 3260.511963 23520.53711 2 2 1 1 metal ion binding Pf13499 ENSMUSG00000090841.2 10 0 High Q9ERG0 LIM domain and actin-binding protein 1 OS=Mus musculus OX=10090 GN=Lima1 PE=1 SV=3 0 375.114 73 53 423 53 753 84 6.6 324380.8684 27463.12573 25191.84375 55911.9375 8 2 1 1 Acetyl [N-Term] cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton metal ion binding;protein binding Pf00412 65970 ENSMUSG00000023022.13 Lima1 15 0 High P13020 Gelsolin OS=Mus musculus OX=10090 GN=Gsn PE=1 SV=3 0 358.391 64 39 362 28 780 85.9 6.18 1058179.753 414687.9463 209249.2148 239344.488 14 7 5 9 cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;extracellular;membrane;nucleus metal ion binding;protein binding Pf00626 227753 ENSMUSG00000026879.14 Gsn 2 Neutrophil degranulation; Caspase-mediated cleavage of cytoskeletal proteins Regulation of actin cytoskeleton; Fc gamma R-mediated phagocytosis; Viral carcinogenesis 13 High Q60605 Myosin light polypeptide 6 OS=Mus musculus OX=10090 GN=Myl6 PE=1 SV=3 0 141.575 89 12 354 3 151 16.9 4.65 556590.4648 194007.2217 20932.8457 222510.832 6 5 1 6 Met-loss+Acetyl [N-Term] cellular component movement membrane catalytic activity;metal ion binding;motor activity;protein binding;structural molecule activity "Pf00036, Pf13405, Pf13499" 17904 ENSMUSG00000090841.2 Myl6 10 RHO GTPases activate PAKs; Smooth Muscle Contraction Oxytocin signaling pathway; Vascular smooth muscle contraction 13 High P17426 AP-2 complex subunit alpha-1 OS=Mus musculus OX=10090 GN=Ap2a1 PE=1 SV=1 0 265.151 63 47 351 34 977 107.6 7.03 313084.1858 522483.2173 46632.19922 63973.60938 10 10 3 6 regulation of biological process;transport membrane protein binding;transporter activity "Pf01602, Pf02296, Pf02883, Pf13646" 11771 ENSMUSG00000060279.14 Ap2a1 7 "WNT5A-dependent internalization of FZD4; Trafficking of GluR2-containing AMPA receptors; VLDLR internalisation and degradation; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Recycling pathway of L1; MHC class II antigen presentation; Cargo recognition for clathrin-mediated endocytosis; LDL clearance" Endocytosis; Endocrine and other factor-regulated calcium reabsorption; Huntington's disease; Synaptic vesicle cycle 0 High Q5SVG5 AP complex subunit beta OS=Mus musculus OX=10090 GN=Ap1b1 PE=1 SV=1 0 272.878 57 52 349 23 916 101.1 5.22 601881.9922 885947.7456 1029764.916 324582.525 6 8 4 6 cell organization and biogenesis;transport cytoplasm;cytosol;Golgi;membrane protein binding;transporter activity "Pf01602, Pf02883, Pf09066, Pf12717, Pf13646" 11764 ENSMUSG00000009090.17 Ap1b1 11 0 High Q5SX40 Myosin-1 OS=Mus musculus OX=10090 GN=Myh1 PE=1 SV=1 0 800.236 57 115 336 14 1942 223.2 5.76 1 1 5296159.871 4783999.446 2365924.165 1953798.9 51 42 17 31 Met-loss+Acetyl [N-Term] metabolic process cytoplasm catalytic activity;motor activity;nucleotide binding;protein binding;structural molecule activity "Pf00038, Pf00063, Pf01576, Pf02736, Pf04111, Pf05622, Pf07888, Pf12128" 17879 ENSMUSG00000056328.14 Myh1 11 Tight junction 96 High G3UW82 "Myosin, heavy polypeptide 2, skeletal muscle, adult OS=Mus musculus OX=10090 GN=Myh2 PE=1 SV=1" 0 745.889 53 108 315 15 1942 223.1 5.77 1 1 156840.9219 13132.23633 1 1 Met-loss+Acetyl [N-Term] cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus Golgi catalytic activity;motor activity;nucleotide binding;protein binding;structural molecule activity "Pf00038, Pf00063, Pf01576, Pf02736, Pf04111, Pf04156, Pf05557, Pf05622, Pf07888, Pf08317, Pf09726, Pf11559, Pf12128, Pf13514" 17882 ENSMUSG00000033196.17 Myh2 11 Regulation of actin dynamics for phagocytic cup formation Tight junction 6 High Q3THE2 Myosin regulatory light chain 12B OS=Mus musculus OX=10090 GN=Myl12b PE=1 SV=2 0 137.117 80 13 293 2 172 19.8 4.84 498379.313 336781.1406 1259182.292 572875.7417 9 8 6 9 regulation of biological process metal ion binding;protein binding "Pf00036, Pf13202, Pf13405, Pf13833" 67938 ENSMUSG00000034868.8 Myl12b 17 RHO GTPases activate PAKs; Smooth Muscle Contraction Leukocyte transendothelial migration; Regulation of actin cytoskeleton; Focal adhesion; Platelet activation; Tight junction 17 High Q3UHU8 General transcription factor II-I OS=Mus musculus OX=10090 GN=Gtf2i PE=1 SV=1 0 190.113 49 44 288 44 962 108.3 7.8 8 4 8 5 3996369.089 5475276.568 763298.1602 957471.1006 35 29 9 19 cellular homeostasis;metabolic process;regulation of biological process cytoplasm;membrane;nucleus DNA binding;protein binding Pf02946 14886 ENSMUSG00000060261.15 Gtf2i 5 0 High D3Z2H9 "Tropomyosin 3, related sequence 7 OS=Mus musculus OX=10090 GN=Tpm3-rs7 PE=3 SV=1" 0 215.159 68 29 280 6 248 29 4.81 Met-loss+Acetyl [N-Term] cell organization and biogenesis protein binding;structural molecule activity "Pf00261, Pf12718" ENSMUSG00000058126.6 14 Striated Muscle Contraction; Smooth Muscle Contraction 0 High E9Q7Q3 Tropomyosin alpha-3 chain OS=Mus musculus OX=10090 GN=Tpm3 PE=1 SV=1 0 229.112 67 29 278 6 248 28.7 4.72 489471.051 65805.45996 100434.5801 283505.793 6 2 3 2 Met-loss+Acetyl [N-Term] cell organization and biogenesis cytoplasm;cytoskeleton;cytosol protein binding;structural molecule activity "Pf00261, Pf12718" 59069 ENSMUSG00000027940.18 Tpm3 3 14 High Q9Z207 Protein diaphanous homolog 3 OS=Mus musculus OX=10090 GN=Diaph3 PE=1 SV=1 0 277.959 53 54 277 54 1171 133.6 7.61 545011.0137 377975.4043 489665.98 364354.1089 7 8 5 8 cell organization and biogenesis cytoplasm;cytosol;nucleus protein binding "Pf02181, Pf06367, Pf06371" 56419 ENSMUSG00000022021.13 Diap3; Diaph3 14 RHO GTPases Activate Formins Regulation of actin cytoskeleton 0 High Q5SX39 Myosin-4 OS=Mus musculus OX=10090 GN=Myh4 PE=2 SV=1 0 634.56 50 90 274 11 1939 222.7 5.74 1 1 1 1 1793685.055 1182568.186 197190.1326 13 10 6 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;response to stimulus cytoplasm;cytosol catalytic activity;motor activity;nucleotide binding;protein binding;RNA binding "Pf00063, Pf00261, Pf01576, Pf02736, Pf04111, Pf05483, Pf05622, Pf08317, Pf09726, Pf12128" 17884 ENSMUSG00000057003.12 Myh4 11 Tight junction 8 High G5E8R2 Tropomyosin alpha-1 chain OS=Mus musculus OX=10090 GN=Tpm1 PE=1 SV=1 0 192.624 77 31 268 6 248 28.7 4.78 13235.58496 1 Met-loss+Acetyl [N-Term] cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus cytoplasm;cytoskeleton protein binding;structural molecule activity "Pf00261, Pf12718" 22003 ENSMUSG00000032366.15 Tpm1 9 0 High Q6ZWQ9 "Myosin, light chain 12A, regulatory, non-sarcomeric OS=Mus musculus OX=10090 GN=Myl12a PE=1 SV=1" 0 143.528 80 13 263 4 172 19.9 4.81 725965.8789 182318.5708 620156.1528 211067.8997 3 5 3 4 cell organization and biogenesis;regulation of biological process metal ion binding;protein binding "Pf00036, Pf13202, Pf13405" 67268 ENSMUSG00000024048.14 Myl12a 17 Ephrin signaling; Smooth Muscle Contraction Leukocyte transendothelial migration; Regulation of actin cytoskeleton; Focal adhesion; Platelet activation; Tight junction 0 High A0A1L1SV25 Alpha-actinin-4 OS=Mus musculus OX=10090 GN=Actn4 PE=1 SV=1 0 317.871 61 47 258 33 932 107 5.36 680010.3323 552029.719 1642193.441 234224.5327 16 15 3 9 metal ion binding;protein binding "Pf00307, Pf00435, Pf08726, Pf11971, Pf13499, Pf13833" ENSMUSG00000054808.15 7 14 High F8WID5 Tropomyosin alpha-1 chain OS=Mus musculus OX=10090 GN=Tpm1 PE=1 SV=1 0 206.246 66 32 242 5 326 37.4 4.72 998348.4363 104189.8569 309105.7832 361527.1484 9 4 3 3 "Pf00261, Pf12718" ENSMUSG00000032366.15 9 15 High Q8BP43 Tropomyosin alpha-1 chain OS=Mus musculus OX=10090 GN=Tpm1 PE=1 SV=1 0 199.168 70 32 242 2 284 32.8 4.77 235162.5195 279774.0117 21817.90039 55306.16797 2 2 1 1 cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus cytoplasm;cytoskeleton protein binding;structural molecule activity "Pf00261, Pf12718" 22003 ENSMUSG00000032366.15 Tpm1 9 5 High P13542 Myosin-8 OS=Mus musculus OX=10090 GN=Myh8 PE=2 SV=2 0 516.406 40 78 240 4 1937 222.6 5.83 1 1 1 1 24595.11133 1 cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process cytoplasm;cytoskeleton catalytic activity;motor activity;nucleotide binding;protein binding "Pf00063, Pf01576, Pf02463, Pf02736, Pf04111, Pf05483, Pf05557, Pf05622, Pf05701, Pf06160, Pf07888, Pf09726, Pf10174, Pf10498, Pf12128, Pf12718, Pf13094, Pf13166, Pf13514, Pf15397" 17885 ENSMUSG00000055775.16 Myh8 11 Striated Muscle Contraction Tight junction 0 High A0A0A0MQA5 Tubulin alpha chain (Fragment) OS=Mus musculus OX=10090 GN=Tuba4a PE=1 SV=1 0 142.519 53 22 236 6 477 52.9 5.19 1 1 1 1 136520.21 3692.187012 28777.61719 2 1 2 cell organization and biogenesis catalytic activity;nucleotide binding;protein binding;structural molecule activity "Pf00091, Pf03953" ENSMUSG00000026202.13 1 0 High O35490 Betaine--homocysteine S-methyltransferase 1 OS=Mus musculus OX=10090 GN=Bhmt PE=1 SV=1 0 197.239 81 26 227 23 407 45 7.9 221246.9272 253356.5784 71212.91406 80813.54907 6 4 2 5 metabolic process cytoplasm;cytosol catalytic activity;metal ion binding;protein binding Pf02574 12116 ENSMUSG00000069324.5; ENSMUSG00000074768.5 Bhmt 13; 18 Sulfur amino acid metabolism; Choline catabolism "Metabolic pathways; Cysteine and methionine metabolism; Glycine, serine and threonine metabolism" 3 High P19157 Glutathione S-transferase P 1 OS=Mus musculus OX=10090 GN=Gstp1 PE=1 SV=2 0 220.076 86 14 213 14 210 23.6 7.87 2 1 2 1 1832847.104 1652974.22 221234.5322 899108.6355 17 16 3 14 Met-loss [N-Term] cell communication;cell proliferation;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus antioxidant activity;catalytic activity;enzyme regulator activity;protein binding "Pf00043, Pf02798" 14870 ENSMUSG00000060803.5; ENSMUSG00000097830.3 Gstp1 19; CHR_MG153_PATCH Glutathione conjugation; Neutrophil degranulation; Detoxification of Reactive Oxygen Species Glutathione metabolism; Platinum drug resistance; Drug metabolism - cytochrome P450; Chemical carcinogenesis; Metabolism of xenobiotics by cytochrome P450; Prostate cancer 0 High E9QN14 SLIT-ROBO Rho GTPase-activating protein 3 OS=Mus musculus OX=10090 GN=Srgap3 PE=1 SV=1 0 214.907 51 46 210 46 1075 121.6 6.57 502641.5732 757233.4922 243930.9321 35874.40332 7 8 2 2 regulation of biological process;response to stimulus cytoplasm enzyme regulator activity;protein binding "Pf00018, Pf00611, Pf00620, Pf07653, Pf14604" 259302 ENSMUSG00000030257.16 Srgap3 6 Rho GTPase cycle 0 High Q3TWV4 AP-2 complex subunit mu OS=Mus musculus OX=10090 GN=Ap2m1 PE=1 SV=1 0 148.494 63 27 208 25 433 49.4 9.54 1028593.255 1903031.13 3274985.729 4357293.208 12 5 2 6 Met-loss [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process;transport membrane;mitochondrion protein binding Pf00928 11773 ENSMUSG00000022841.14 Ap2m1 16 2 High P28666 Murinoglobulin-2 OS=Mus musculus OX=10090 GN=Mug2 PE=1 SV=2 0 308.061 47 51 203 34 1451 162.3 6.74 5692891.362 484848.6094 2520398.594 1134082.956 19 5 6 7 regulation of biological process extracellular enzyme regulator activity "Pf00207, Pf01835, Pf07677, Pf07678, Pf07703, Pf10569, Pf11974, Pf13249" 17837 ENSMUSG00000030131.8 Mug2 6 17 High E9QAI5 CAD protein OS=Mus musculus OX=10090 GN=Cad PE=1 SV=1 0 174.86 32 47 192 44 2162 236.1 6.49 680377.9705 374923.1274 380274.4336 489103.7803 10 12 6 22 metabolic process catalytic activity;metal ion binding;nucleotide binding "Pf00117, Pf00185, Pf00289, Pf00988, Pf01071, Pf01979, Pf02142, Pf02222, Pf02729, Pf02786, Pf02787, Pf07478, Pf07722, Pf08443, Pf13147, Pf13535, Pf13594, Pf15632" ENSMUSG00000013629.16 5 0 High P35700 Peroxiredoxin-1 OS=Mus musculus OX=10090 GN=Prdx1 PE=1 SV=1 0 112.482 86 17 191 15 199 22.2 8.12 1 2 1 3 1043299.896 1400807.952 101524.4355 700543.7949 11 9 4 11 cell proliferation;cellular homeostasis;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;mitochondrion;nucleus;organelle lumen antioxidant activity;catalytic activity;protein binding;RNA binding "Pf00578, Pf08534, Pf10417" 18477 ENSMUSG00000028691.12 Prdx1 4 Detoxification of Reactive Oxygen Species; TP53 Regulates Metabolic Genes Peroxisome 3 High Q5SYD0 Unconventional myosin-Id OS=Mus musculus OX=10090 GN=Myo1d PE=1 SV=1 0 245.79 55 55 189 54 1006 116 9.41 983132.6309 6007574.029 532361.0557 698610.032 11 11 8 10 regulation of biological process;transport cytosol;endoplasmic reticulum;endosome;membrane catalytic activity;motor activity;nucleotide binding;protein binding "Pf00063, Pf06017" 338367 ENSMUSG00000035441.14 Myo1d 11 1 High E9Q634 Unconventional myosin-Ie OS=Mus musculus OX=10090 GN=Myo1e PE=1 SV=1 0 200.948 50 46 185 40 1107 126.7 9.07 205546.5068 224025.4041 76020.30322 6 6 7 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton catalytic activity;motor activity;nucleotide binding;protein binding "Pf00018, Pf00063, Pf06017, Pf07653, Pf14604" 71602 ENSMUSG00000032220.10 Myo1e 9 6 High Q99JY9 Actin-related protein 3 OS=Mus musculus OX=10090 GN=Actr3 PE=1 SV=3 0 167.354 73 23 176 19 418 47.3 5.88 378880.0205 333986.6484 174798.248 230894.3301 8 4 3 8 cell differentiation;cell division;cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane nucleotide binding;protein binding;structural molecule activity Pf00022 74117 ENSMUSG00000026341.16 Actr3 1 RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling; Regulation of actin dynamics for phagocytic cup formation 4 High Q9JJ28 Protein flightless-1 homolog OS=Mus musculus OX=10090 GN=Flii PE=1 SV=1 0 210.5 47 43 169 43 1271 144.7 6.06 298409.1433 39711.38477 315500.5449 116199.1943 8 2 4 5 Acetyl [N-Term] cell organization and biogenesis;development;metabolic process;regulation of biological process cytoplasm;cytoskeleton;cytosol;nucleus protein binding "Pf00626, Pf12799, Pf13855" 14248 ENSMUSG00000002812.4 Flii 11 0 High Q9CQ19 Myosin regulatory light polypeptide 9 OS=Mus musculus OX=10090 GN=Myl9 PE=1 SV=3 0 108.108 62 11 167 4 172 19.8 4.92 7102.133789 10750.45996 2 1 metal ion binding;protein binding "Pf00036, Pf13202, Pf13405, Pf13833" 98932 ENSMUSG00000067818.6 Myl9 2 RHO GTPases activate PAKs; Smooth Muscle Contraction Oxytocin signaling pathway; Leukocyte transendothelial migration; Regulation of actin cytoskeleton; Focal adhesion; cGMP-PKG signaling pathway; cAMP signaling pathway; Vascular smooth muscle contraction; Tight junction 0 High A2AIM4 Tropomyosin beta chain OS=Mus musculus OX=10090 GN=Tpm2 PE=1 SV=1 0 158.16 76 34 165 20 284 33 4.69 276239.9861 21193.63086 11551.49805 13 2 1 cell organization and biogenesis cytoplasm;cytoskeleton protein binding;structural molecule activity "Pf00261, Pf12718" 22004 ENSMUSG00000028464.16 Tpm2 4 14 High Q9JHJ0 Tropomodulin-3 OS=Mus musculus OX=10090 GN=Tmod3 PE=1 SV=1 0 124.513 58 20 165 19 352 39.5 5.14 110738.4749 314833.2432 51667.1665 114186.4414 6 5 3 4 cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton protein binding Pf03250 50875 ENSMUSG00000058587.8 Tmod3 9 1 High P11276 Fibronectin OS=Mus musculus OX=10090 GN=Fn1 PE=1 SV=4 0 239.346 22 38 162 38 2477 272.4 5.59 14 7 19 10 11459378.03 7656251.949 776273.1855 838671.6836 33 25 8 16 cell differentiation;cell organization and biogenesis;cellular component movement;defense response;metabolic process;regulation of biological process;response to stimulus extracellular;membrane enzyme regulator activity;metal ion binding;protein binding "Pf00039, Pf00040, Pf00041" 14268 ENSMUSG00000026193.15 Fn1 1 ECM proteoglycans; Molecules associated with elastic fibres; Degradation of the extracellular matrix; Cell surface interactions at the vascular wall; Post-translational protein phosphorylation; Integrin cell surface interactions; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); p130Cas linkage to MAPK signaling for integrins; MET activates PTK2 signaling; GRB2:SOS provides linkage to MAPK signaling for Integrins ; Platelet degranulation ; Syndecan interactions; Fibronectin matrix formation AGE-RAGE signaling pathway in diabetic complications; Regulation of actin cytoskeleton; Focal adhesion; Small cell lung cancer; Proteoglycans in cancer; Pathways in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway; Amoebiasis; Bacterial invasion of epithelial cells 0 High P00329 Alcohol dehydrogenase 1 OS=Mus musculus OX=10090 GN=Adh1 PE=1 SV=2 0 121.317 61 18 161 18 375 39.7 8.1 118115.0684 111169.75 143141.0586 3 2 2 metabolic process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00107, Pf08240" 11522 ENSMUSG00000074207.10 Adh1 3 RA biosynthesis pathway; Ethanol oxidation; Abacavir metabolism Drug metabolism - cytochrome P450; Retinol metabolism; Metabolic pathways; Fatty acid degradation; Glycolysis / Gluconeogenesis; Chemical carcinogenesis; Tyrosine metabolism; Metabolism of xenobiotics by cytochrome P450 0 High E9Q3Z5 Supervillin OS=Mus musculus OX=10090 GN=Svil PE=1 SV=1 0 243.319 36 59 153 59 2056 230.3 6.62 717567.1641 329565.1094 150277.9502 178029.7266 19 10 4 11 cell organization and biogenesis protein binding "Pf00626, Pf02209" ENSMUSG00000024236.18 18 0 High Q91Z83 Myosin-7 OS=Mus musculus OX=10090 GN=Myh7 PE=2 SV=1 0 333.34 35 60 151 31 1935 222.7 5.76 1 1 99220.67676 374219.8447 130776.1289 106821.2026 6 9 3 4 Met-loss+Acetyl [N-Term] cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton catalytic activity;motor activity;nucleotide binding;protein binding;structural molecule activity "Pf00038, Pf00063, Pf01576, Pf02736, Pf04111, Pf04156, Pf05483, Pf05622, Pf06160, Pf07888, Pf09726, Pf12128, Pf13514, Pf13851" 140781 ENSMUSG00000053093.15 Myh7 14 Hypertrophic cardiomyopathy (HCM); Dilated cardiomyopathy; cGMP-PKG signaling pathway; Cardiac muscle contraction; Viral myocarditis; Tight junction; Adrenergic signaling in cardiomyocytes 3 High Q9D8E6 60S ribosomal protein L4 OS=Mus musculus OX=10090 GN=Rpl4 PE=1 SV=3 0 92.465 49 21 151 21 419 47.1 11 346495.3267 467822.251 137713.2939 353999.4709 10 10 2 11 Met-loss+Acetyl [N-Term] metabolic process;regulation of biological process cytoplasm;endoplasmic reticulum;membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity "Pf00573, Pf14374" 67891 ENSMUSG00000032399.8 Rpl4 9 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q62167 ATP-dependent RNA helicase DDX3X OS=Mus musculus OX=10090 GN=Ddx3x PE=1 SV=3 0 126.146 52 30 149 7 662 73.1 7.18 232869.3269 295152.8252 49584.91357 188457.6191 14 9 5 11 cell death;cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;DNA binding;enzyme regulator activity;nucleotide binding;protein binding;RNA binding "Pf00270, Pf00271, Pf04851" 13205 ENSMUSG00000000787.12 Ddx3x X Neutrophil degranulation RIG-I-like receptor signaling pathway; Hepatitis B; Viral carcinogenesis 25 High Q8R3N1 Nucleolar protein 14 OS=Mus musculus OX=10090 GN=Nop14 PE=1 SV=2 0 155.87 38 32 145 32 860 98.7 7.59 639943.9294 281681.6777 255246.2715 268446.5742 6 4 3 4 metabolic process membrane;nucleus protein binding;RNA binding Pf04147 75416 ENSMUSG00000036693.12 Nop14 5 Major pathway of rRNA processing in the nucleolus and cytosol 0 High P0DP27 Calmodulin-2 OS=Mus musculus OX=10090 GN=Calm2 PE=1 SV=1 0 108.639 89 13 144 13 149 16.8 4.22 591088.5166 356640.96 136110.7559 419355.307 7 4 4 8 Met-loss+Acetyl [N-Term] regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;nucleus enzyme regulator activity;metal ion binding;protein binding "Pf00036, Pf08726, Pf12763, Pf13202, Pf13405, Pf13499, Pf13833, Pf14658" 12315; 12313; 12314 ENSMUSG00000001175.13; ENSMUSG00000036438.12; ENSMUSG00000019370.10 Calm3; Calm1; Calm2 7; 12; 17 Oxytocin signaling pathway; Dopaminergic synapse; Ras signaling pathway; Insulin signaling pathway; Long-term potentiation; Amphetamine addiction; Tuberculosis; Melanogenesis; Oocyte meiosis; Pertussis; Neurotrophin signaling pathway; cGMP-PKG signaling pathway; Rap1 signaling pathway; Calcium signaling pathway; Salivary secretion; Alzheimer's disease; Alcoholism; cAMP signaling pathway; Vascular smooth muscle contraction; Aldosterone synthesis and secretion; GnRH signaling pathway; Olfactory transduction; Phototransduction; Gastric acid secretion; Renin secretion; Circadian entrainment; Glioma; Estrogen signaling pathway; Glucagon signaling pathway; Phosphatidylinositol signaling system; Adrenergic signaling in cardiomyocytes; Inflammatory mediator regulation of TRP channels 0 High E9PZ16 Basement membrane-specific heparan sulfate proteoglycan core protein OS=Mus musculus OX=10090 GN=Hspg2 PE=1 SV=1 0 157.273 18 48 143 48 4383 469.5 6.47 22 12 1 26 13 1 7065274.886 3541426.715 1403804.287 1300278.964 40 28 22 27 cell differentiation;cell organization and biogenesis;transport extracellular metal ion binding;protein binding "Pf00008, Pf00047, Pf00052, Pf00053, Pf00054, Pf00057, Pf02210, Pf07679, Pf07686, Pf12785, Pf13385, Pf13895, Pf13927" 15530 ENSMUSG00000028763.17 Hspg2 4 HS-GAG degradation; A tetrasaccharide linker sequence is required for GAG synthesis; Laminin interactions; Degradation of the extracellular matrix; Signaling by GPCR; Retinoid metabolism and transport; Integrin cell surface interactions; HS-GAG biosynthesis; Non-integrin membrane-ECM interactions Hepatitis B; Proteoglycans in cancer; ECM-receptor interaction 0 High A1BN54 Alpha actinin 1a OS=Mus musculus OX=10090 GN=Actn1 PE=1 SV=1 0 134.118 52 35 142 19 887 102.7 5.48 36843.29443 4837.322266 154214.5469 213356.1782 3 1 1 4 Acetyl [N-Term] cell differentiation;cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton;membrane;nucleus metal ion binding;protein binding;RNA binding "Pf00307, Pf00435, Pf08726, Pf11971, Pf13499, Pf13833" 109711 ENSMUSG00000015143.15 Actn1 12 3 High P61161 Actin-related protein 2 OS=Mus musculus OX=10090 GN=Actr2 PE=1 SV=1 0 126.548 47 14 137 14 394 44.7 6.74 39794.07739 20721.26367 15718.37402 35760.33496 4 1 1 2 cell division;cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;membrane nucleotide binding;protein binding;structural molecule activity Pf00022 66713 ENSMUSG00000020152.7 Actr2 11 RHO GTPases Activate WASPs and WAVEs; Neutrophil degranulation; Clathrin-mediated endocytosis; EPHB-mediated forward signaling; Regulation of actin dynamics for phagocytic cup formation 0 High Q5SWN2 Replication protein A subunit OS=Mus musculus OX=10090 GN=Rpa1 PE=1 SV=2 0 118.659 40 23 129 23 644 71.4 8.18 43258.25732 151995.4502 16407.37891 9360.957764 3 2 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus chromosome;nucleus DNA binding;metal ion binding "Pf01336, Pf01485, Pf04057, Pf08646" 68275 ENSMUSG00000000751.13 Rpa1 11 0 High Q8BHD8 Protein-L-isoaspartate O-methyltransferase domain-containing protein 2 OS=Mus musculus OX=10090 GN=Pcmtd2 PE=2 SV=1 0 52.824 48 16 125 16 359 40.7 6.46 96575.19946 26207.94897 51609.07983 47385.69922 6 4 3 4 Met-loss [N-Term] metabolic process cytoplasm catalytic activity "Pf01135, Pf12847, Pf13847" 245867 ENSMUSG00000027589.14 Pcmtd2 2 0 High A2A839 Protein 4.1 OS=Mus musculus OX=10090 GN=Epb41 PE=1 SV=1 0 194.08 48 31 124 19 639 72.4 6.62 578164.2776 863177.5669 297053.0469 365909.874 11 6 2 6 cell division;cell organization and biogenesis;regulation of biological process;transport cytoplasm;cytoskeleton;cytosol;membrane;nucleus protein binding;structural molecule activity "Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380" 269587 ENSMUSG00000028906.16 Epb4.1; Epb41 4 11 High P12970 60S ribosomal protein L7a OS=Mus musculus OX=10090 GN=Rpl7a PE=1 SV=2 0 103.809 50 17 123 17 266 30 10.56 1 2 1199093.939 1809519.017 425072.1895 1175266.868 15 9 6 7 metabolic process cytoplasm;membrane;nucleus;ribosome protein binding;RNA binding Pf01248 27176 ENSMUSG00000062647.16 Rpl7a 2 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High P14873 Microtubule-associated protein 1B OS=Mus musculus OX=10090 GN=Map1b PE=1 SV=2 0 148.157 22 32 121 32 2464 270.1 4.83 1 1 2356788.951 226275.3818 169899.9648 1558263.381 21 7 3 5 Met-loss+Acetyl [N-Term] cell growth;cell organization and biogenesis;cellular component movement;regulation of biological process;transport cytoplasm;cytoskeleton;cytosol;membrane protein binding 17755 ENSMUSG00000052727.5 Map1b; Mtap1b 13 0 High E0CYV0 Protein-L-isoaspartate O-methyltransferase OS=Mus musculus OX=10090 GN=Pcmt1 PE=1 SV=1 0 117.716 53 16 121 16 286 30.4 7.24 197856.25 32205.91968 16498.62305 105336.7195 5 2 1 3 metabolic process;regulation of biological process cytoplasm;cytosol;membrane catalytic activity "Pf01135, Pf01209, Pf05175, Pf08241, Pf12847, Pf13489, Pf13659, Pf13847" 18537 ENSMUSG00000019795.17 Pcmt1 10 Protein repair 0 High P58252 Elongation factor 2 OS=Mus musculus OX=10090 GN=Eef2 PE=1 SV=2 0 97.897 45 31 119 30 858 95.3 6.83 635825.7517 433704.1855 325281.1367 440269.813 19 12 3 12 Met-loss [N-Term] cell differentiation;cell proliferation;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;nucleus;ribosome catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00009, Pf00679, Pf03144, Pf03764, Pf14492" 13629 ENSMUSG00000034994.10 Eef2 10 Peptide chain elongation; Neutrophil degranulation; Protein methylation; Synthesis of diphthamide-EEF2 Oxytocin signaling pathway; AMPK signaling pathway 0 High Q9CVB6 Actin-related protein 2/3 complex subunit 2 OS=Mus musculus OX=10090 GN=Arpc2 PE=1 SV=3 0 111.457 54 20 116 20 300 34.3 7.36 145832.6953 46091.87305 3306.471436 90631.82324 6 2 1 4 Met-loss [N-Term] cell organization and biogenesis;regulation of biological process;response to stimulus cell surface;cytoplasm;cytoskeleton;endosome;membrane protein binding;structural molecule activity Pf04045 76709 ENSMUSG00000006304.14 Arpc2 1 RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling; Regulation of actin dynamics for phagocytic cup formation Endocytosis; Regulation of actin cytoskeleton; Salmonella infection; Fc gamma R-mediated phagocytosis; Bacterial invasion of epithelial cells 0 High A6PWS5 Gelsolin (Fragment) OS=Mus musculus OX=10090 GN=Gsn PE=1 SV=1 0 90.409 65 12 116 1 251 28 7.02 Met-loss [N-Term] cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;extracellular;membrane;nucleus metal ion binding;protein binding Pf00626 227753 ENSMUSG00000026879.14 Gsn 2 0 High A2AMW0 F-actin-capping protein subunit beta OS=Mus musculus OX=10090 GN=Capzb PE=1 SV=1 0 127.26 70 20 115 5 260 29.3 6.92 135322.9635 98860.43628 95875.71289 106301.8164 9 7 2 5 cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton;membrane protein binding Pf01115 12345 ENSMUSG00000028745.18 Capzb 4 16 High Q5SUH6 Clathrin interactor 1 OS=Mus musculus OX=10090 GN=Clint1 PE=1 SV=1 0 155.929 40 22 111 1 641 69.7 6.65 cell organization and biogenesis;transport cytoplasm;Golgi;membrane protein binding "Pf01417, Pf07651" 216705 ENSMUSG00000006169.19 Clint1 11 Golgi Associated Vesicle Biogenesis 0 High G5E8G6 Unconventional myosin-Vb OS=Mus musculus OX=10090 GN=Myo5b PE=1 SV=1 0 169.835 31 43 110 42 1818 210.4 7.09 657447.9768 350847.377 381125.1719 397063.457 11 6 3 5 cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;endosome catalytic activity;motor activity;nucleotide binding;protein binding "Pf00063, Pf01576, Pf01843, Pf02463, Pf03938, Pf04111, Pf05557, Pf05622, Pf05667, Pf07888, Pf07926, Pf12128, Pf13514" 17919 ENSMUSG00000025885.18 Myo5b 18 Vasopressin regulates renal water homeostasis via Aquaporins 1 High Q5SUH7 Clathrin interactor 1 OS=Mus musculus OX=10090 GN=Clint1 PE=1 SV=1 0 154.883 38 22 110 1 623 67.7 6.42 53939.81787 27055.42676 4318.282227 64087.25732 5 2 1 2 cell organization and biogenesis;transport cytoplasm;Golgi;membrane protein binding "Pf01417, Pf07651" 216705 ENSMUSG00000006169.19 Clint1 11 Golgi Associated Vesicle Biogenesis 22 High Q61656 Probable ATP-dependent RNA helicase DDX5 OS=Mus musculus OX=10090 GN=Ddx5 PE=1 SV=2 0 67.14 33 21 110 15 614 69.2 8.92 193557.4893 190863.0459 77699.52344 68237.12061 8 6 1 4 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus;spliceosomal complex catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00270, Pf00271, Pf08061" 13207 Ddx5 11 5 High O35488 Very long-chain acyl-CoA synthetase OS=Mus musculus OX=10090 GN=Slc27a2 PE=1 SV=2 0 104.592 47 26 106 26 620 70.4 8.9 142051.377 80752.7207 70943.25269 201613.4711 6 3 4 12 metabolic process;transport endoplasmic reticulum;membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding;protein binding;transporter activity "Pf00501, Pf13193" 26458 ENSMUSG00000027359.16 Slc27a2 2 Alpha-oxidation of phytanate; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; Neutrophil degranulation; Synthesis of bile acids and bile salts via 24-hydroxycholesterol PPAR signaling pathway; Insulin resistance; Peroxisome 0 High P54869 "Hydroxymethylglutaryl-CoA synthase, mitochondrial OS=Mus musculus OX=10090 GN=Hmgcs2 PE=1 SV=2" 0 103.84 48 21 105 21 508 56.8 8.41 1873357.34 4140976.632 1627271.404 4 5 4 metabolic process membrane;mitochondrion;organelle lumen catalytic activity "Pf01154, Pf08540, Pf08545" 15360 ENSMUSG00000027875.12 Hmgcs2 3 Synthesis of Ketone Bodies "PPAR signaling pathway; Valine, leucine and isoleucine degradation; Metabolic pathways; Terpenoid backbone biosynthesis; Butanoate metabolism; Synthesis and degradation of ketone bodies" 0 High P47757 F-actin-capping protein subunit beta OS=Mus musculus OX=10090 GN=Capzb PE=1 SV=3 0 109.465 65 16 105 1 277 31.3 5.74 17645.05859 1 Met-loss+Acetyl [N-Term] cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton;membrane protein binding Pf01115 12345 ENSMUSG00000028745.18 Capzb 4 COPI-independent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; MHC class II antigen presentation; Factors involved in megakaryocyte development and platelet production; HSP90 chaperone cycle for steroid hormone receptors (SHR) Endocytosis 0 High P11679 "Keratin, type II cytoskeletal 8 OS=Mus musculus OX=10090 GN=Krt8 PE=1 SV=4" 0 81.527 43 22 102 16 490 54.5 5.82 1 1 1002783.202 2312321.909 506843.2031 1134698.781 5 4 2 4 cell death;cell differentiation;cell organization and biogenesis;development;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane;nucleus catalytic activity;motor activity;protein binding;structural molecule activity "Pf00038, Pf01576, Pf04111, Pf09726, Pf10186, Pf12128, Pf13166, Pf13514, Pf15003" 16691 ENSMUSG00000049382.9 Krt8 15 Formation of the cornified envelope 4 High Q62095 ATP-dependent RNA helicase DDX3Y OS=Mus musculus OX=10090 GN=Ddx3y PE=1 SV=2 0 95.19 37 24 101 1 658 73.4 7.53 13444.92383 1 metabolic process;regulation of biological process cytoplasm;cytosol;membrane;nucleus catalytic activity;DNA binding;nucleotide binding;RNA binding "Pf00270, Pf00271, Pf04851" 26900 ENSMUSG00000069045.11 Ddx3y Y 0 High P05977 "Myosin light chain 1/3, skeletal muscle isoform OS=Mus musculus OX=10090 GN=Myl1 PE=1 SV=2" 0 112.705 68 12 100 9 188 20.6 5.03 150178.1094 74642.28906 70082.95313 18252.10938 6 3 2 2 metal ion binding Pf13499 17901 ENSMUSG00000061816.15 Myl1 1 Striated Muscle Contraction 7 High A0A0R4J293 Protein-glutamine gamma-glutamyltransferase K OS=Mus musculus OX=10090 GN=Tgm1 PE=1 SV=1 0 111.499 40 26 99 26 815 89.7 6.58 412778.7188 290474.2104 79357.01367 128226.4248 3 7 3 4 cell differentiation;metabolic process;regulation of biological process membrane catalytic activity;metal ion binding "Pf00868, Pf00927, Pf01841" 21816 ENSMUSG00000022218.15 Tgm1 14 Formation of the cornified envelope 0 High A0A3B2WDD2 Ribosomal protein OS=Mus musculus OX=10090 GN=Rpl10a PE=1 SV=1 0 81.855 46 10 97 10 190 21.6 9.98 491289.873 726341.6777 234870.6899 7 7 5 0 High P20918 Plasminogen OS=Mus musculus OX=10090 GN=Plg PE=1 SV=3 0 102.378 41 24 97 24 812 90.7 6.6 109412.9894 371160.752 19099.63867 5 1 1 cell differentiation;cell organization and biogenesis;cellular component movement;cellular homeostasis;coagulation;metabolic process;regulation of biological process cell surface;extracellular;membrane catalytic activity;protein binding "Pf00024, Pf00051, Pf00089, Pf09342, Pf13365" 18815 ENSMUSG00000059481.4 Plg 17 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); LDL remodeling; Plasma lipoprotein remodeling; Dissolution of Fibrin Clot; Platelet degranulation ; Signaling by PDGF; Activation of Matrix Metalloproteinases Staphylococcus aureus infection; Complement and coagulation cascades; Influenza A; Neuroactive ligand-receptor interaction 0 High P99027 60S acidic ribosomal protein P2 OS=Mus musculus OX=10090 GN=Rplp2 PE=1 SV=3 0 64.461 81 8 95 8 115 11.6 4.54 2 1 2 2 649915.7649 1702468.422 51565.02002 277393.019 6 6 2 6 metabolic process membrane;ribosome structural molecule activity Pf00428 67186 ENSMUSG00000025508.13 Rplp2 7 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q9WV32 Actin-related protein 2/3 complex subunit 1B OS=Mus musculus OX=10090 GN=Arpc1b PE=1 SV=4 0 126.29 53 15 95 14 372 41 8.35 5484993.997 8687809.387 3647659.938 2837870.097 4 4 1 3 Met-loss+Acetyl [N-Term] cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytoskeleton protein binding;structural molecule activity Pf00400 11867 ENSMUSG00000029622.16 Arpc1b 5 RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling; Regulation of actin dynamics for phagocytic cup formation Endocytosis; Regulation of actin cytoskeleton; Salmonella infection; Fc gamma R-mediated phagocytosis; Bacterial invasion of epithelial cells 1 High P28665 Murinoglobulin-1 OS=Mus musculus OX=10090 GN=Mug1 PE=1 SV=3 0 132.18 28 29 95 12 1476 165.2 6.42 1 1 555827.1504 572029.2129 876487.6094 211711.4668 8 3 3 3 regulation of biological process extracellular enzyme regulator activity "Pf00207, Pf01835, Pf07677, Pf07678, Pf07703, Pf10569, Pf11974, Pf13249" 17836 ENSMUSG00000059908.9 Mug1 6 0 High B1AR69 "Myosin, heavy polypeptide 13, skeletal muscle OS=Mus musculus OX=10090 GN=Myh13 PE=1 SV=1" 0 163.495 16 33 95 1 1938 223.4 5.57 36673.71484 17099.91211 1 1 cell communication;cell organization and biogenesis;regulation of biological process;response to stimulus catalytic activity;motor activity;nucleotide binding;protein binding;structural molecule activity "Pf00038, Pf00063, Pf00261, Pf01576, Pf02463, Pf02736, Pf05483, Pf05557, Pf05622, Pf05701, Pf07888, Pf09726, Pf10174, Pf12128, Pf12718, Pf13166, Pf13514" 544791 ENSMUSG00000060180.12 Myh13 11 Striated Muscle Contraction Tight junction 0 High A2BH40 AT-rich interactive domain-containing protein 1A OS=Mus musculus OX=10090 GN=Arid1a PE=1 SV=1 0 104.369 16 25 94 25 2283 241.9 6.68 340087.0701 149954.7969 189832.2976 5 2 4 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport nucleus DNA binding;protein binding "Pf01388, Pf12031" 93760 ENSMUSG00000007880.16 Arid1a 4 RMTs methylate histone arginines; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 0 High Q61194 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Mus musculus OX=10090 GN=Pik3c2a PE=1 SV=2 0 137.704 34 44 93 44 1686 190.6 8.02 465408.3403 354774.7236 88252.66406 124747.2642 7 5 1 4 Met-loss+Acetyl [N-Term] cell communication;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;Golgi;membrane;nucleus catalytic activity;nucleotide binding;protein binding "Pf00168, Pf00454, Pf00613, Pf00787, Pf00792, Pf00794, Pf04621" 18704 Pik3c2a 7 Metabolic pathways; Inositol phosphate metabolism; Phosphatidylinositol signaling system 0 High Q9WUM4 Coronin-1C OS=Mus musculus OX=10090 GN=Coro1c PE=1 SV=2 0 102.973 53 27 93 27 474 53.1 7.08 281767.9302 166625.6875 189806.3643 298921.1558 4 1 2 3 cell organization and biogenesis;cellular component movement;regulation of biological process;transport cytoplasm;cytoskeleton;membrane protein binding "Pf00400, Pf08953, Pf08954" 23790 ENSMUSG00000004530.12 Coro1c 5 0 High P24270 Catalase OS=Mus musculus OX=10090 GN=Cat PE=1 SV=4 0 129.572 61 25 93 25 527 59.8 7.88 1 1 742563.9282 383259.4238 420450.4023 90765.28467 16 6 2 4 Met-loss+Acetyl [N-Term] cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytosol;endoplasmic reticulum;Golgi;membrane;mitochondrion;vacuole antioxidant activity;catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00199, Pf06628" 12359 ENSMUSG00000027187.10 Cat 2 Neutrophil degranulation; Detoxification of Reactive Oxygen Species FoxO signaling pathway; Tryptophan metabolism; Amyotrophic lateral sclerosis (ALS); Longevity regulating pathway; Carbon metabolism; Glyoxylate and dicarboxylate metabolism; Longevity regulating pathway - multiple species; Peroxisome 0 High P62743 AP-2 complex subunit sigma OS=Mus musculus OX=10090 GN=Ap2s1 PE=1 SV=1 0 28.224 34 6 92 6 142 17 6.18 44128.5957 365865.3477 9414.266602 22867.94727 3 2 1 1 transport membrane protein binding;transporter activity Pf01217 232910 ENSMUSG00000008036.11 Ap2s1 7 "WNT5A-dependent internalization of FZD4; Trafficking of GluR2-containing AMPA receptors; VLDLR internalisation and degradation; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Recycling pathway of L1; MHC class II antigen presentation; Cargo recognition for clathrin-mediated endocytosis; LDL clearance" Endocytosis; Endocrine and other factor-regulated calcium reabsorption; Huntington's disease; Synaptic vesicle cycle 0 High E9Q1Y3 Apolipoprotein B-100 (Fragment) OS=Mus musculus OX=10090 GN=Apob PE=1 SV=1 0 146.211 13 47 91 47 4456 503.6 6.83 250183.9465 210754.2666 221301.9102 141139.6829 9 8 3 8 cellular component movement;metabolic process;regulation of biological process;transport endoplasmic reticulum transporter activity "Pf01347, Pf06448, Pf09172, Pf12491" ENSMUSG00000020609.14 12 0 High P27659 60S ribosomal protein L3 OS=Mus musculus OX=10090 GN=Rpl3 PE=1 SV=3 0 71.915 38 14 89 14 403 46.1 10.21 698836.4829 586885.1089 199093.1484 303709.2847 6 4 1 5 cell organization and biogenesis;metabolic process;response to stimulus cytoplasm;cytosol;nucleus;ribosome RNA binding;structural molecule activity Pf00297 27367 ENSMUSG00000060036.13 Rpl3 15 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q6IRU2 Tropomyosin alpha-4 chain OS=Mus musculus OX=10090 GN=Tpm4 PE=1 SV=3 0 108.538 61 24 89 22 248 28.5 4.68 499363.7734 158386.6406 104111.5664 108822.542 2 1 2 4 Met-loss+Acetyl [N-Term] cell differentiation;cell organization and biogenesis cytoplasm;cytoskeleton;membrane metal ion binding;protein binding;structural molecule activity "Pf00261, Pf12718" 326618 ENSMUSG00000031799.9 Tpm4 8 Striated Muscle Contraction; Smooth Muscle Contraction Hypertrophic cardiomyopathy (HCM); Dilated cardiomyopathy; Cardiac muscle contraction; Adrenergic signaling in cardiomyocytes 0 High Q8VCQ8 Caldesmon 1 OS=Mus musculus OX=10090 GN=Cald1 PE=1 SV=1 0 155.726 52 28 88 28 530 60.4 7.37 101952.3613 94702.09961 107678.4219 540052.4492 5 2 2 3 Acetyl [N-Term] cell organization and biogenesis;regulation of biological process;response to stimulus membrane protein binding Pf02029 109624 ENSMUSG00000029761.16 Cald1 6 Smooth Muscle Contraction Vascular smooth muscle contraction 0 High P09542 Myosin light chain 3 OS=Mus musculus OX=10090 GN=Myl3 PE=1 SV=4 0 84.012 51 8 88 5 204 22.4 5.1 144732.8281 1 regulation of biological process catalytic activity;metal ion binding;motor activity;protein binding Pf13499 17897 ENSMUSG00000059741.13 Myl3 9 Striated Muscle Contraction Hypertrophic cardiomyopathy (HCM); Dilated cardiomyopathy; Cardiac muscle contraction; Adrenergic signaling in cardiomyocytes 0 High Q8CG16 Complement C1r-A subcomponent OS=Mus musculus OX=10090 GN=C1ra PE=1 SV=1 0 100.441 42 20 86 19 707 80 5.66 3 3 2953525.416 902141.5244 278299.249 1124536.1 17 9 6 10 defense response;metabolic process;regulation of biological process;response to stimulus catalytic activity;metal ion binding "Pf00084, Pf00089, Pf00431, Pf07645, Pf12662, Pf14670" 50909 ENSMUSG00000055172.10 C1ra 6 Regulation of Complement cascade; Classical antibody-mediated complement activation Staphylococcus aureus infection; Phagosome; Complement and coagulation cascades; Pertussis; Systemic lupus erythematosus 1 High P55096 ATP-binding cassette sub-family D member 3 OS=Mus musculus OX=10090 GN=Abcd3 PE=1 SV=2 0 107.541 39 19 85 19 659 75.4 9.26 173231.1865 122055.0527 63318.03906 394847.2134 5 3 1 9 cell organization and biogenesis;metabolic process;response to stimulus;transport membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding;protein binding;transporter activity "Pf00005, Pf06472" 19299 ENSMUSG00000028127.10 Abcd3 3 ABC transporters in lipid homeostasis ABC transporters; Peroxisome 0 High A0A0R4J0I6 Acyl-CoA dehydrogenase family member 11 OS=Mus musculus OX=10090 GN=Acad11 PE=1 SV=1 0 88.436 31 19 80 19 779 87.3 8.43 162895.0415 46673.48047 151386.2773 50323.98315 5 3 2 3 Acetyl [N-Term] metabolic process membrane;mitochondrion;nucleus catalytic activity;nucleotide binding "Pf00441, Pf01636, Pf02770, Pf02771, Pf08028" 102632 ENSMUSG00000090150.10 Acad11 9 Mitochondrial Fatty Acid Beta-Oxidation 0 High P47738 "Aldehyde dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Aldh2 PE=1 SV=1" 0 68.01 43 17 80 16 519 56.5 7.62 6 1 6 1 2381882.232 1588643.042 506387.5254 527805.1934 14 11 6 9 metabolic process;regulation of biological process mitochondrion;organelle lumen catalytic activity;nucleotide binding;protein binding Pf00171 11669 ENSMUSG00000029455.14 Aldh2 5 Metabolism of serotonin; Ethanol oxidation "Histidine metabolism; Pyruvate metabolism; Arginine and proline metabolism; Tryptophan metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Lysine degradation; Fatty acid degradation; Glycolysis / Gluconeogenesis; beta-Alanine metabolism; Ascorbate and aldarate metabolism; Glycerolipid metabolism; Pentose and glucuronate interconversions" 0 High A0A0R4J135 Selenium-binding protein 2 OS=Mus musculus OX=10090 GN=Selenbp2 PE=1 SV=1 0 101.1 66 23 78 5 472 52.6 6.18 528139.089 1166155.914 155309.8594 272384.3926 9 6 1 7 transport cytoplasm;membrane;nucleus "Pf05694, Pf10282" 20342 ENSMUSG00000068877.12 Selenbp2 3 17 High P16015 Carbonic anhydrase 3 OS=Mus musculus OX=10090 GN=Ca3 PE=1 SV=3 0 68.146 77 15 77 15 260 29.3 7.37 11 2 1 15 3 1 5086284.722 2778398.721 1089842.932 448021.6631 14 12 9 9 metabolic process;response to stimulus cytoplasm;cytosol catalytic activity;metal ion binding Pf00194 12350 ENSMUSG00000027559.5 Car3 3 Reversible hydration of carbon dioxide Nitrogen metabolism 0 High Q9D0E1 Heterogeneous nuclear ribonucleoprotein M OS=Mus musculus OX=10090 GN=Hnrnpm PE=1 SV=3 0 71.607 33 18 77 18 729 77.6 8.63 3 3 336748.6621 2173643.588 12889.66699 313930.166 8 12 1 7 Met-loss+Acetyl [N-Term] metabolic process;regulation of biological process cell surface;membrane;nucleus;spliceosomal complex protein binding;RNA binding "Pf00076, Pf11532, Pf11608, Pf13893, Pf14259" 76936 ENSMUSG00000059208.14 Hnrnpm 17 mRNA Splicing - Major Pathway; FGFR2 alternative splicing Spliceosome 0 High Q80X90 Filamin-B OS=Mus musculus OX=10090 GN=Flnb PE=1 SV=3 0 112.045 18 32 76 32 2602 277.7 5.71 293149.304 113920.3984 321073.0791 381984.2222 14 4 4 9 cell differentiation;cell organization and biogenesis cytoplasm;cytoskeleton;cytosol;membrane;nucleus protein binding;RNA binding "Pf00307, Pf00630" 286940 ENSMUSG00000025278.8 Flnb 14 ISG15 antiviral mechanism MAPK signaling pathway; Focal adhesion; Proteoglycans in cancer; Salmonella infection 0 High O70570 Polymeric immunoglobulin receptor OS=Mus musculus OX=10090 GN=Pigr PE=1 SV=1 0 85.364 34 17 75 17 771 84.9 5.4 416999.4756 221974.9795 134217.6338 9 7 5 cell organization and biogenesis;regulation of biological process;response to stimulus;transport extracellular;membrane protein binding;receptor activity;signal transducer activity 18703 ENSMUSG00000026417.13 Pigr 1 Neutrophil degranulation Intestinal immune network for IgA production 0 High Q6PB66 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Mus musculus OX=10090 GN=Lrpprc PE=1 SV=2" 0 77.313 22 24 72 24 1392 156.5 6.83 431345.7788 677615.8237 54160.3125 138973.2842 10 8 2 7 metabolic process;regulation of biological process;transport chromosome;cytoplasm;cytoskeleton;membrane;mitochondrion;nucleus catalytic activity;DNA binding;protein binding;RNA binding "Pf12854, Pf13041, Pf13812" 72416 ENSMUSG00000024120.12 Lrpprc 17 0 High Q91X83 S-adenosylmethionine synthase isoform type-1 OS=Mus musculus OX=10090 GN=Mat1a PE=1 SV=1 0 85.726 37 13 72 10 396 43.5 5.82 25075.10303 66522.61255 17473.19336 29742.84375 3 4 1 4 cell organization and biogenesis;metabolic process cytosol catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00438, Pf02772, Pf02773" 11720 ENSMUSG00000037798.6 Mat1a 14 "Sulfur amino acid metabolism; Metabolism of ingested SeMet, Sec, MeSec into H2Se; Methylation" Metabolic pathways; Biosynthesis of amino acids; Cysteine and methionine metabolism 3 High P17563 Methanethiol oxidase OS=Mus musculus OX=10090 GN=Selenbp1 PE=1 SV=2 0 91.043 53 20 72 2 472 52.5 6.29 cell differentiation;transport cytoplasm;cytosol;membrane;nucleus "Pf05694, Pf10282" 20341 ENSMUSG00000068874.13 Selenbp1 3 0 High Q63880 Carboxylesterase 3A OS=Mus musculus OX=10090 GN=Ces3a PE=1 SV=2 0 98.4 48 14 71 11 571 63.3 6.14 186037.0469 182058.0703 75379.4707 22067.5957 5 5 4 3 metabolic process endoplasmic reticulum;organelle lumen catalytic activity "Pf00135, Pf00326, Pf00756, Pf07859" 382053 ENSMUSG00000069922.12 Ces3a 8 Phase I - Functionalization of compounds; LDL clearance 3 High E9Q3W4 Plectin OS=Mus musculus OX=10090 GN=Plec PE=1 SV=1 0 127.422 15 50 71 48 4386 498.8 5.68 427865.3723 192174.0044 57630.70703 315905.4768 22 11 1 13 cell organization and biogenesis;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane protein binding;RNA binding;structural molecule activity "Pf00307, Pf00681, Pf07812, Pf11971" 18810 ENSMUSG00000022565.15 Plec 15 2 High E9Q9B3 SPRY domain-containing 3 OS=Mus musculus OX=10090 GN=Spryd3 PE=1 SV=1 0 85.557 51 13 70 13 442 49.7 6.16 645196.2148 92970.84961 321508.6943 9 3 11 protein binding Pf00622 223918 ENSMUSG00000036966.15 Spryd3 15 0 High Q8CH09 SURP and G-patch domain-containing protein 2 OS=Mus musculus OX=10090 GN=Sugp2 PE=1 SV=2 0 73.693 35 23 70 23 1067 118 8.31 152971.8394 163119.7168 74947.29883 201511.105 7 5 3 5 metabolic process nucleus RNA binding "Pf01585, Pf01805" 234373 ENSMUSG00000036054.15 Sugp2 8 0 High P35980 60S ribosomal protein L18 OS=Mus musculus OX=10090 GN=Rpl18 PE=1 SV=3 0 41.948 42 9 69 9 188 21.6 11.78 1 1 179296.9277 292711.125 33009.18359 167100.5527 5 1 1 3 metabolic process cytoplasm;cytosol;endoplasmic reticulum;membrane;nucleus;ribosome RNA binding;structural molecule activity Pf00828 19899 ENSMUSG00000059070.16 Rpl18 7 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q6PFA2 Clathrin light chain OS=Mus musculus OX=10090 GN=Clta PE=1 SV=1 0 47.487 30 8 68 8 218 23.6 4.5 11631.01953 1 cell division;cell organization and biogenesis;transport cytoplasm;cytoskeleton;membrane protein binding;structural molecule activity Pf01086 12757 ENSMUSG00000028478.18 Clta 4 "WNT5A-dependent internalization of FZD4; Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis; VLDLR internalisation and degradation; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Formation of annular gap junctions; Recycling pathway of L1; MHC class II antigen presentation; Cargo recognition for clathrin-mediated endocytosis; LDL clearance" Endocytosis; Endocrine and other factor-regulated calcium reabsorption; Lysosome; Huntington's disease; Synaptic vesicle cycle; Bacterial invasion of epithelial cells 0 High Q3UZ39 Leucine-rich repeat flightless-interacting protein 1 OS=Mus musculus OX=10090 GN=Lrrfip1 PE=1 SV=2 0 112.956 51 23 68 15 729 79.2 4.82 302949.9084 313460.2188 9983.063477 105628.8101 4 2 1 5 metabolic process;regulation of biological process cytoplasm;cytosol;membrane;nucleus DNA binding;protein binding Pf09738 16978 ENSMUSG00000026305.15 Lrrfip1 1 8 High Q80XN0 "D-beta-hydroxybutyrate dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Bdh1 PE=1 SV=2" 0 60.422 48 12 68 12 343 38.3 9.01 36609.1875 121486.124 15809.5874 2 3 2 metabolic process membrane;mitochondrion;organelle lumen catalytic activity "Pf00106, Pf08643, Pf13561" 71911 ENSMUSG00000046598.14 Bdh1 16 Synthesis of Ketone Bodies; Utilization of Ketone Bodies Metabolic pathways; Butanoate metabolism; Synthesis and degradation of ketone bodies 0 High P24549 Retinal dehydrogenase 1 OS=Mus musculus OX=10090 GN=Aldh1a1 PE=1 SV=5 0 104.683 53 18 68 11 501 54.4 7.8 1 1 472224.6738 1154835.654 930133.0625 1054559.254 4 4 3 4 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;nucleus catalytic activity;nucleotide binding;protein binding "Pf00171, Pf05893, Pf07368" 11668 ENSMUSG00000053279.6 Aldh1a1 19 RA biosynthesis pathway; Ethanol oxidation; Fructose catabolism Retinol metabolism; Metabolic pathways 8 High Q61176 Arginase-1 OS=Mus musculus OX=10090 GN=Arg1 PE=1 SV=1 0 75.807 58 13 68 13 323 34.8 7.01 37101.58203 49381.74683 14134.79785 32328.79492 2 3 1 4 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus catalytic activity;metal ion binding Pf00491 11846 ENSMUSG00000019987.9 Arg1 10 Neutrophil degranulation; Urea cycle Arginine and proline metabolism; Metabolic pathways; Biosynthesis of amino acids; Arginine biosynthesis; Amoebiasis 0 High P61358 60S ribosomal protein L27 OS=Mus musculus OX=10090 GN=Rpl27 PE=1 SV=2 0 35.976 51 8 67 8 136 15.8 10.56 224046.7188 288656.9961 30014.54102 211014.3066 7 4 1 5 metabolic process membrane;nucleus;ribosome RNA binding;structural molecule activity "Pf00467, Pf01777" 19942; 108167922 ENSMUSG00000063316.13; ENSMUSG00000073640.2 Rpl27; LOC108167922 11; 18 Ribosome 0 High Q9QZS3 Protein numb homolog OS=Mus musculus OX=10090 GN=Numb PE=1 SV=1 0 105.663 34 17 66 17 653 70.8 8.65 95291.79297 107813.5273 17958.3125 763444.1602 2 3 1 2 cell differentiation;cell division;cell organization and biogenesis;cell proliferation;development;regulation of biological process cytoplasm;endosome;membrane;nucleus protein binding "Pf00640, Pf06311, Pf08416" 18222 ENSMUSG00000021224.14 Numb 12 Recycling pathway of L1; Hedgehog 'on' state; Degradation of GLI1 by the proteasome Notch signaling pathway 0 High E9Q2H1 E3 ubiquitin-protein ligase UBR5 OS=Mus musculus OX=10090 GN=Ubr5 PE=1 SV=2 0 180.962 30 51 65 51 2792 308.1 5.83 963849.6685 310622.6865 216340.8594 528996.377 10 7 1 9 Met-loss+Acetyl [N-Term] 0 High P62918 60S ribosomal protein L8 OS=Mus musculus OX=10090 GN=Rpl8 PE=1 SV=2 0 69.915 58 13 65 13 257 28 11.03 1 1 839715.7422 64950.15234 100450.7432 7 1 3 metabolic process;response to stimulus cytoplasm;membrane;ribosome protein binding;RNA binding;structural molecule activity "Pf00181, Pf03947" 26961 ENSMUSG00000003970.8 Rpl8 15 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High P03975 IgE-binding protein OS=Mus musculus OX=10090 GN=Iap PE=2 SV=1 0 58.237 29 13 65 13 557 62.7 9.31 148766.249 112497.6475 336748.9375 237031.5391 6 3 2 4 metabolic process protein binding "Pf00607, Pf00665" 0 High Q8C2Q8 ATP synthase subunit gamma OS=Mus musculus OX=10090 GN=Atp5c1 PE=1 SV=1 0 51.828 50 14 65 14 274 30.2 8.84 1176920.689 3129770.618 986522.2461 1355331.091 6 4 4 7 metabolic process;transport membrane;mitochondrion catalytic activity;RNA binding;transporter activity Pf00231 11949 ENSMUSG00000025781.14 Atp5c1 2 0 High E9QQ30 Eukaryotic translation initiation factor 2-alpha kinase 3 OS=Mus musculus OX=10090 GN=Eif2ak3 PE=1 SV=1 0 77.003 34 25 65 25 1114 124.6 5.25 1 1 89011.49463 645133.2969 190932.0332 827491.1455 4 10 5 13 cell communication;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;membrane catalytic activity;nucleotide binding;protein binding "Pf00069, Pf07714, Pf13360, Pf14531" 13666 ENSMUSG00000031668.14 Eif2ak3 6 PERK regulates gene expression 0 High P47754 F-actin-capping protein subunit alpha-2 OS=Mus musculus OX=10090 GN=Capza2 PE=1 SV=3 0 66.845 71 13 64 11 286 32.9 5.85 1973521.122 1455218.919 88830.50293 5 5 4 Met-loss+Acetyl [N-Term] cell organization and biogenesis;regulation of biological process cytoskeleton;membrane protein binding Pf01267 12343 ENSMUSG00000015733.13 Capza2 6 Advanced glycosylation endproduct receptor signaling; COPI-independent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; MHC class II antigen presentation; Factors involved in megakaryocyte development and platelet production; HSP90 chaperone cycle for steroid hormone receptors (SHR) Endocytosis 2 High Q9Z1R2 Large proline-rich protein BAG6 OS=Mus musculus OX=10090 GN=Bag6 PE=1 SV=1 0 81.261 21 15 64 15 1154 121 5.71 1 1 138887.0679 799791.0708 108272.7917 4 8 5 cell death;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;extracellular;membrane;nucleus protein binding "Pf00240, Pf11976, Pf12057" 224727 ENSMUSG00000024392.17 Bag6 17 0 High G3X9T7 Galectin-9 OS=Mus musculus OX=10090 GN=Lgals9 PE=1 SV=1 0 61.807 44 11 64 11 353 40 9.31 27130.0625 248369.3115 1 2 Met-loss+Acetyl [N-Term] regulation of biological process;response to stimulus cytoplasm;cytosol;extracellular;nucleus enzyme regulator activity;protein binding Pf00337 16859 ENSMUSG00000001123.15 Lgals9 11 0 High Q4LDG0 Bile acyl-CoA synthetase OS=Mus musculus OX=10090 GN=Slc27a5 PE=1 SV=2 0 73.968 37 18 64 18 689 76.2 8.38 114802.3926 459717.7871 30910.68213 3 3 2 metabolic process;transport endoplasmic reticulum;membrane catalytic activity;nucleotide binding;protein binding;transporter activity "Pf00501, Pf13193" 26459 ENSMUSG00000030382.15 Slc27a5 7 Recycling of bile acids and salts; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; Synthesis of bile acids and bile salts via 24-hydroxycholesterol PPAR signaling pathway; Metabolic pathways; Primary bile acid biosynthesis; Insulin resistance; Bile secretion 0 High D3Z656 Synaptojanin-1 OS=Mus musculus OX=10090 GN=Synj1 PE=1 SV=1 0 111.526 31 35 63 30 1607 176.2 7.72 187169.5139 105155.7432 17917.85547 610132.7949 7 3 1 4 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;membrane catalytic activity;protein binding;RNA binding "Pf02383, Pf03372, Pf08952" 104015 ENSMUSG00000022973.17 Synj1 16 "Synthesis of PIPs at the plasma membrane; Clathrin-mediated endocytosis; Synthesis of IP2, IP, and Ins in the cytosol; Synthesis of IP3 and IP4 in the cytosol" 5 High Q8VCH0 "3-ketoacyl-CoA thiolase B, peroxisomal OS=Mus musculus OX=10090 GN=Acaa1b PE=1 SV=1" 0 76.846 55 14 62 5 424 44 8.51 103425.6064 17855.54102 21714.64038 65886.75781 2 1 1 3 metabolic process mitochondrion catalytic activity "Pf00108, Pf02803, Pf08541" 235674 ENSMUSG00000010651.4 Acaa1b 9 Beta-oxidation of very long chain fatty acids; Neutrophil degranulation; alpha-linolenic acid (ALA) metabolism "PPAR signaling pathway; Fatty acid metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Fatty acid degradation; alpha-Linolenic acid metabolism; Biosynthesis of unsaturated fatty acids; Peroxisome" 9 High Q5SX75 Prolyl 4-hydroxylase subunit alpha-2 OS=Mus musculus OX=10090 GN=P4ha2 PE=1 SV=1 0 66.097 40 15 62 15 537 61 5.9 18735.28271 175763.5535 239512.3701 2 5 9 metabolic process cytosol;endoplasmic reticulum catalytic activity;metal ion binding;protein binding "Pf03171, Pf08336, Pf13640" 18452 ENSMUSG00000018906.14 P4ha2 11 Arginine and proline metabolism; Metabolic pathways 0 High Q9WTX6 Cullin-1 OS=Mus musculus OX=10090 GN=Cul1 PE=1 SV=1 0 69.027 33 19 61 19 776 89.6 8 1349689.641 585044.0872 85176.40625 618686.8413 3 8 2 11 cell death;cell proliferation;metabolic process catalytic activity;protein binding "Pf00888, Pf10557" 26965 ENSMUSG00000029686.15 Cul1 6 NIK-->noncanonical NF-kB signaling; Degradation of beta-catenin by the destruction complex; Prolactin receptor signaling; SCF-beta-TrCP mediated degradation of Emi1; Regulation of RUNX2 expression and activity; SCF(Skp2)-mediated degradation of p27/p21; Neddylation; GLI3 is processed to GLI3R by the proteasome; Dectin-1 mediated noncanonical NF-kB signaling; Activation of NF-kappaB in B cells; Activated TLR4 signalling; Antigen processing: Ubiquitination & Proteasome degradation; Degradation of GLI1 by the proteasome; FCERI mediated NF-kB activation; Regulation of PLK1 Activity at G2/M Transition; Downstream TCR signaling; Cyclin D associated events in G1; Interleukin-1 family signaling; Iron uptake and transport; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; MAP3K8 (TPL2)-dependent MAPK1/3 activation Herpes simplex infection; Wnt signaling pathway; Ubiquitin mediated proteolysis; Circadian rhythm; Oocyte meiosis; Cell cycle; TGF-beta signaling pathway; Hedgehog signaling pathway; Protein processing in endoplasmic reticulum 0 High Q9DB15 "39S ribosomal protein L12, mitochondrial OS=Mus musculus OX=10090 GN=Mrpl12 PE=1 SV=2" 0 36.574 53 8 60 8 201 21.7 9.29 174415.9053 324000.2305 94535.57813 95821.48633 4 3 1 3 cell organization and biogenesis;metabolic process;regulation of biological process mitochondrion;ribosome structural molecule activity Pf00542 56282 ENSMUSG00000039640.7 Mrpl12 11 Mitochondrial translation termination; Mitochondrial translation elongation Ribosome 0 High A0A0R4J0Z1 Protein disulfide-isomerase A4 OS=Mus musculus OX=10090 GN=Pdia4 PE=1 SV=1 0 92.767 40 25 60 25 641 72.3 5.22 199640.2422 215148.7012 43805.62891 429747.4727 6 5 1 9 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cell surface;endoplasmic reticulum;organelle lumen catalytic activity;metal ion binding;RNA binding "Pf00085, Pf01216, Pf13098, Pf13848, Pf13905" 12304 ENSMUSG00000025823.9 Pdia4 6 Thyroid hormone synthesis; Protein processing in endoplasmic reticulum 0 High Q63886 UDP-glucuronosyltransferase 1-1 OS=Mus musculus OX=10090 GN=Ugt1a1 PE=1 SV=2 0 79.078 43 16 60 8 535 60 8.62 321333.4038 88102.5498 71940.22607 99492.74634 4 2 3 4 defense response;metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;membrane catalytic activity;enzyme regulator activity;protein binding "Pf00201, Pf04101" 394436 ENSMUSG00000089960.1 Ugt1a1 1 Heme degradation; Glucuronidation Steroid hormone biosynthesis; Drug metabolism - cytochrome P450; Retinol metabolism; Metabolic pathways; Drug metabolism - other enzymes; Ascorbate and aldarate metabolism; Chemical carcinogenesis; Porphyrin and chlorophyll metabolism; Pentose and glucuronate interconversions; Metabolism of xenobiotics by cytochrome P450 7 High Q99LB2 Dehydrogenase/reductase SDR family member 4 OS=Mus musculus OX=10090 GN=Dhrs4 PE=1 SV=3 0 49.49 41 11 60 11 279 29.9 9.38 3 3 219061.5723 977730.6211 538346.3164 536271.0337 6 6 5 7 cell organization and biogenesis;metabolic process membrane;mitochondrion;nucleus catalytic activity;protein binding "Pf00106, Pf08659, Pf13561" 28200 ENSMUSG00000022210.6 Dhrs4 14 RA biosynthesis pathway Retinol metabolism; Metabolic pathways; Peroxisome 0 High Q9DBM2 Peroxisomal bifunctional enzyme OS=Mus musculus OX=10090 GN=Ehhadh PE=1 SV=4 0 69.318 32 18 59 18 718 78.3 9.13 120807.0928 95338.44531 72918.25098 4 3 4 metabolic process;transport cytosol;mitochondrion catalytic activity;protein binding "Pf00378, Pf00725, Pf02254, Pf02737" 74147 ENSMUSG00000022853.6 Ehhadh 16 Beta-oxidation of very long chain fatty acids "PPAR signaling pathway; Fatty acid metabolism; Tryptophan metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Lysine degradation; Fatty acid degradation; Butanoate metabolism; beta-Alanine metabolism; Propanoate metabolism; Carbon metabolism; Peroxisome" 0 High P11352 Glutathione peroxidase 1 OS=Mus musculus OX=10090 GN=Gpx1 PE=1 SV=2 0 44.394 65 12 59 12 201 22.3 7.21 111743.9419 142142.8716 14063.14453 26246.47363 5 3 2 3 cell death;cell differentiation;cell proliferation;cellular component movement;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;mitochondrion;nucleus antioxidant activity;catalytic activity;protein binding Pf00255 14775 ENSMUSG00000063856.7 Gpx1 9 Synthesis of 12-eicosatetraenoic acid derivatives; Synthesis of 15-eicosatetraenoic acid derivatives; Purine catabolism; Detoxification of Reactive Oxygen Species Glutathione metabolism; Amyotrophic lateral sclerosis (ALS); Thyroid hormone synthesis; Huntington's disease; Arachidonic acid metabolism 0 High Q921H8 "3-ketoacyl-CoA thiolase A, peroxisomal OS=Mus musculus OX=10090 GN=Acaa1a PE=1 SV=1" 0 81.742 54 13 57 4 424 43.9 8.44 114706.6426 209930.375 5880.135742 32985.43945 2 1 1 2 metabolic process membrane;mitochondrion catalytic activity "Pf00108, Pf02803, Pf08541" 113868 ENSMUSG00000036138.16 Acaa1a 9 Beta-oxidation of very long chain fatty acids; Neutrophil degranulation; alpha-linolenic acid (ALA) metabolism "PPAR signaling pathway; Fatty acid metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Fatty acid degradation; alpha-Linolenic acid metabolism; Biosynthesis of unsaturated fatty acids; Peroxisome" 0 High P98078 Disabled homolog 2 OS=Mus musculus OX=10090 GN=Dab2 PE=1 SV=2 0 81.176 36 18 57 18 766 82.3 6.1 420651.9941 15116.66113 26886.43945 122901.6465 2 1 1 2 Met-loss+Acetyl [N-Term] cell death;cell differentiation;cell organization and biogenesis;development;regulation of biological process;response to stimulus;transport cytoplasm;membrane;nucleus protein binding;receptor activity Pf00640 13132 Dab2 15 Endocytosis 0 High E9QNT8 Ankyrin-1 OS=Mus musculus OX=10090 GN=Ank1 PE=1 SV=1 0 85.12 16 22 57 21 1862 204.1 6.55 183389.8633 620209.625 141659.7361 104671.9738 6 1 3 4 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;endoplasmic reticulum;membrane;nucleus protein binding "Pf00023, Pf00531, Pf00791, Pf12796, Pf13606, Pf13637, Pf13857" 11733 ENSMUSG00000031543.18 Ank1 8 Proteoglycans in cancer 1 High P59999 Actin-related protein 2/3 complex subunit 4 OS=Mus musculus OX=10090 GN=Arpc4 PE=1 SV=3 0 47.99 61 8 57 8 168 19.7 8.43 6194.545898 158349.821 7027.81543 1 2 1 Met-loss+Acetyl [N-Term] cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton protein binding;structural molecule activity Pf05856 68089 ENSMUSG00000079426.13 Arpc4 6 RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling; Regulation of actin dynamics for phagocytic cup formation Endocytosis; Regulation of actin cytoskeleton; Salmonella infection; Fc gamma R-mediated phagocytosis; Bacterial invasion of epithelial cells 0 High I7HLV2 60S ribosomal protein L10 (Fragment) OS=Mus musculus OX=10090 GN=Rpl10 PE=1 SV=1 0 42.64 41 7 57 7 201 23.1 10.01 155087.4863 62921.30078 111799.46 189233.1875 3 1 2 4 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;endoplasmic reticulum;membrane;nucleus;ribosome RNA binding;structural molecule activity Pf00252 110954 ENSMUSG00000008682.13 Rpl10 X 0 High A0A0G2JEP4 Leucine-rich repeat flightless-interacting protein 2 OS=Mus musculus OX=10090 GN=Lrrfip2 PE=1 SV=1 0 84.896 44 16 56 1 424 48.4 5.54 129104.821 24254.7793 165339.1445 1923709.887 5 1 3 3 metabolic process;regulation of biological process;response to stimulus protein binding "Pf04111, Pf09738" 71268 ENSMUSG00000032497.16 Lrrfip2 9 13 High Q8CI94 "Glycogen phosphorylase, brain form OS=Mus musculus OX=10090 GN=Pygb PE=1 SV=3" 0 47.605 25 15 56 8 843 96.7 6.73 7 3 11 9 13725881.93 9207231.961 5105177.5 2669082.494 7 7 1 8 metabolic process cytoplasm;membrane catalytic activity;protein binding Pf00343 110078 ENSMUSG00000033059.7 Pygb 2 Neutrophil degranulation Insulin signaling pathway; Metabolic pathways; Insulin resistance; Starch and sucrose metabolism; Glucagon signaling pathway 0 High P09103 Protein disulfide-isomerase OS=Mus musculus OX=10090 GN=P4hb PE=1 SV=2 0 60.014 35 13 56 13 509 57 4.88 136547.8672 32180.23438 555823.3604 6 1 8 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;membrane;organelle lumen catalytic activity;metal ion binding;protein binding;RNA binding "Pf00085, Pf01216, Pf13098, Pf13848, Pf13899, Pf13905" 18453 ENSMUSG00000025130.11 P4hb 11 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Detoxification of Reactive Oxygen Species; Chylomicron assembly; Interleukin-12 family signaling; VLDL assembly; Hedgehog ligand biogenesis; Collagen biosynthesis and modifying enzymes Protein processing in endoplasmic reticulum 0 High E9QN52 Leucine-rich repeat flightless-interacting protein 2 OS=Mus musculus OX=10090 GN=Lrrfip2 PE=1 SV=1 0 86.111 47 16 56 1 415 47.1 5.68 metabolic process;regulation of biological process;response to stimulus protein binding "Pf04111, Pf09738" 71268 ENSMUSG00000032497.16 Lrrfip2 9 0 High Q8VEK3 Heterogeneous nuclear ribonucleoprotein U OS=Mus musculus OX=10090 GN=Hnrnpu PE=1 SV=1 0 41.203 21 13 56 13 800 87.9 6.24 1 1 235484.2891 831139.4668 187360.9609 4 7 5 cell differentiation;metabolic process;regulation of biological process;response to stimulus cell surface;chromosome;cytoplasm;membrane;nucleus;spliceosomal complex DNA binding;nucleotide binding;protein binding;RNA binding "Pf00622, Pf13671" 51810 ENSMUSG00000039630.10; ENSMUSG00000111145.1 Hnrnpu 1; CHR_MG4281_PATCH mRNA Splicing - Major Pathway Spliceosome 0 High P07901 Heat shock protein HSP 90-alpha OS=Mus musculus OX=10090 GN=Hsp90aa1 PE=1 SV=4 0 54.507 17 13 55 1 733 84.7 5.01 cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;cytosol;membrane;nucleus catalytic activity;enzyme regulator activity;nucleotide binding;protein binding;RNA binding "Pf00183, Pf02518, Pf13589" 15519 ENSMUSG00000021270.13 Hsp90aa1 12 "Anchoring of the basal body to the plasma membrane; The role of GTSE1 in G2/M progression after G2 checkpoint; VEGFR2 mediated vascular permeability; Downregulation of ERBB2 signaling; AURKA Activation by TPX2; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; HSF1 activation; Attenuation phase; Regulation of PLK1 Activity at G2/M Transition; Neutrophil degranulation; Recruitment of NuMA to mitotic centrosomes; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation; Regulation of actin dynamics for phagocytic cup formation; HSP90 chaperone cycle for steroid hormone receptors (SHR); eNOS activation; Sema3A PAK dependent Axon repulsion; EPHB-mediated forward signaling" Progesterone-mediated oocyte maturation; NOD-like receptor signaling pathway; Pathways in cancer; Antigen processing and presentation; PI3K-Akt signaling pathway; Protein processing in endoplasmic reticulum; Estrogen signaling pathway; Prostate cancer 0 High Q61584 Fragile X mental retardation syndrome-related protein 1 OS=Mus musculus OX=10090 GN=Fxr1 PE=1 SV=2 0 98.305 39 20 55 18 677 76.2 6.98 62542.70801 299282.8835 64034.28516 606669.1987 3 4 2 6 cell differentiation;development;regulation of biological process cytoplasm;cytosol;membrane;nucleus protein binding;RNA binding "Pf00013, Pf05641, Pf12235, Pf13014" 14359 ENSMUSG00000027680.15 Fxr1 3 RNA transport 2 High E9QAJ9 Rho GTPase-activating protein 17 OS=Mus musculus OX=10090 GN=Arhgap17 PE=1 SV=1 0 104.537 43 21 55 21 818 88.9 8.12 2 2 73975.56543 933232.7813 540191.5957 4 7 7 cell organization and biogenesis;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;membrane;nucleus enzyme regulator activity;protein binding "Pf00620, Pf03114" 70497 ENSMUSG00000030766.15 Arhgap17 7 0 High Q501J6 Probable ATP-dependent RNA helicase DDX17 OS=Mus musculus OX=10090 GN=Ddx17 PE=1 SV=1 0 44.906 24 14 54 8 650 72.4 8.59 98718.96631 57530.91406 3246.11499 4 1 1 cell differentiation;cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;nucleus catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00270, Pf00271" 67040 Ddx17 15 0 High Q9DB20 "ATP synthase subunit O, mitochondrial OS=Mus musculus OX=10090 GN=Atp5po PE=1 SV=1" 0 51.904 63 11 53 11 213 23.3 9.99 1 2 75109.47217 460626.8496 130092.4141 645277.6953 5 5 1 6 metabolic process;transport membrane;mitochondrion;nucleus catalytic activity;protein binding;transporter activity Pf00213 28080; 102641678 ENSMUSG00000022956.10 Atp5o; LOC100047429; LOC102641678 16; 3 Cristae formation; Formation of ATP by chemiosmotic coupling Metabolic pathways; Huntington's disease; Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High Q8K310 Matrin-3 OS=Mus musculus OX=10090 GN=Matr3 PE=1 SV=1 0 60.478 24 15 53 15 846 94.6 6.25 225241.8784 1197414.74 402418.4639 206687.2971 8 13 7 10 defense response;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus metal ion binding;protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 17184 ENSMUSG00000037236.14 Matr3 18 0 High P26151 High affinity immunoglobulin gamma Fc receptor I OS=Mus musculus OX=10090 GN=Fcgr1 PE=1 SV=1 0 44.211 23 9 52 9 404 44.9 6.09 2 2 663852.0544 588936.8267 111436.0859 179526.4932 7 6 1 3 cell organization and biogenesis;defense response;regulation of biological process;response to stimulus;transport membrane protein binding;receptor activity;signal transducer activity "Pf00047, Pf10066, Pf13895, Pf13927" 14129 ENSMUSG00000015947.10 Fcgr1 3 Cross-presentation of soluble exogenous antigens (endosomes); Role of phospholipids in phagocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR activation Staphylococcus aureus infection; Tuberculosis; Osteoclast differentiation; Phagosome; Transcriptional misregulation in cancer; Fc gamma R-mediated phagocytosis; Systemic lupus erythematosus; Leishmaniasis; Hematopoietic cell lineage 0 High P27773 Protein disulfide-isomerase A3 OS=Mus musculus OX=10090 GN=Pdia3 PE=1 SV=2 0 64.438 47 18 52 18 505 56.6 6.21 1 1 394562.677 809707.9805 427435.9014 8 4 11 cell communication;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;endoplasmic reticulum;extracellular;membrane;mitochondrion;nucleus;organelle lumen catalytic activity;protein binding;RNA binding "Pf00085, Pf13098, Pf13848, Pf13899, Pf13905" 14827 ENSMUSG00000027248.13 Pdia3 2 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Calnexin/calreticulin cycle; ER-Phagosome pathway" Antigen processing and presentation; Protein processing in endoplasmic reticulum 0 High Q8VCW8 "Medium-chain acyl-CoA ligase ACSF2, mitochondrial OS=Mus musculus OX=10090 GN=Acsf2 PE=1 SV=1" 0 71.717 37 16 52 16 615 67.9 8.18 216450.3081 129951.2261 54041.54297 84289.13281 7 4 1 3 metabolic process mitochondrion catalytic activity;nucleotide binding "Pf00501, Pf13193" 264895 ENSMUSG00000076435.3 Acsf2 11 Mitochondrial Fatty Acid Beta-Oxidation 0 High P97351 40S ribosomal protein S3a OS=Mus musculus OX=10090 GN=Rps3a PE=1 SV=3 0 44.875 47 11 52 11 264 29.9 9.73 144616.5491 161678.8945 26303.00781 131008.0454 5 4 1 5 cell differentiation;metabolic process;regulation of biological process cytoplasm;cytosol;endoplasmic reticulum;nucleus;ribosome protein binding;RNA binding;structural molecule activity Pf01015 20091 ENSMUSG00000028081.6 Rps3a; Rps3a1 3 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High A0A0A0MQ68 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Gcdh PE=1 SV=1" 0 76.226 44 12 52 12 447 49.5 8.72 520039.9727 316195.873 161998.8574 321813.1582 7 4 3 9 metabolic process membrane;mitochondrion catalytic activity;nucleotide binding "Pf00441, Pf02770, Pf02771, Pf08028" 270076 ENSMUSG00000003809.14 Gcdh 8 Tryptophan metabolism; Metabolic pathways; Lysine degradation; Fatty acid degradation 0 High P19253 60S ribosomal protein L13a OS=Mus musculus OX=10090 GN=Rpl13a PE=1 SV=4 0 24.151 33 7 51 7 203 23.4 11.02 124228.4141 99289.86133 20264.92969 64531.66113 2 4 1 3 Met-loss [N-Term]; Met-loss+Acetyl [N-Term] cellular component movement;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus;ribosome RNA binding;structural molecule activity Pf00572 22121 ENSMUSG00000074129.13 Rpl13a 7 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High B2RXQ4 Nek1 protein OS=Mus musculus OX=10090 GN=Nek1 PE=1 SV=1 0 55.593 21 17 51 17 1178 133.8 5.38 131566.3794 741227.3477 305019.5547 439891.3477 4 9 5 11 cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00069, Pf07714, Pf14531" 18004 ENSMUSG00000031644.19 Nek1 8 0 High Q8C570 mRNA export factor OS=Mus musculus OX=10090 GN=Rae1 PE=1 SV=1 0 50.824 41 12 51 12 368 40.9 7.83 2124739.252 919126.9072 97238.42676 453347.7852 4 7 4 7 cell division;cell organization and biogenesis;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;nucleus protein binding;RNA binding Pf00400 66679 ENSMUSG00000027509.11 Rae1 2 Transcriptional regulation by small RNAs; SUMOylation of RNA binding proteins; snRNP Assembly; SUMOylation of chromatin organization proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of Glucokinase by Glucokinase Regulatory Protein; Transport of Mature mRNA derived from an Intron-Containing Transcript; SUMOylation of DNA damage response and repair proteins; SUMOylation of DNA replication proteins Influenza A; RNA transport 0 High E9PVY8 Microtubule-actin cross-linking factor 1 OS=Mus musculus OX=10090 GN=Macf1 PE=1 SV=2 0 120.036 8 40 51 39 7355 831.4 5.41 396095.2007 175546.3174 98420.20337 246013.0774 15 4 3 8 cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;Golgi;membrane catalytic activity;metal ion binding;protein binding;RNA binding "Pf00036, Pf00307, Pf00435, Pf00681, Pf02187, Pf02463, Pf03938, Pf11971, Pf13499, Pf13514, Pf13833" 11426 ENSMUSG00000028649.17 Macf1 4 0 High Q01853 Transitional endoplasmic reticulum ATPase OS=Mus musculus OX=10090 GN=Vcp PE=1 SV=4 0 58.401 34 17 50 17 806 89.3 5.26 460902.5684 197431.248 202381.457 7 6 5 Met-loss+Acetyl [N-Term] cell communication;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;endoplasmic reticulum;membrane;nucleus;proteasome catalytic activity;enzyme regulator activity;nucleotide binding;protein binding;RNA binding "Pf00004, Pf00910, Pf01057, Pf01078, Pf02359, Pf02933, Pf05496, Pf05673, Pf06068, Pf07724, Pf07726, Pf07728, Pf09336, Pf13191, Pf13207, Pf13401" 269523 ENSMUSG00000028452.7 Vcp 4 N-glycan trimming in the ER and Calnexin/Calreticulin cycle; Protein methylation; Translesion Synthesis by POLH; HSF1 activation; Ovarian tumor domain proteases; Hedgehog ligand biogenesis; ABC-family proteins mediated transport; Neutrophil degranulation Legionellosis; Protein processing in endoplasmic reticulum 0 High Q9QXS6 Drebrin OS=Mus musculus OX=10090 GN=Dbn1 PE=1 SV=4 0 54.954 22 12 50 12 706 77.2 4.49 56290.41895 40194.94922 153061.9414 9867.030273 3 1 1 1 Met-loss+Acetyl [N-Term] cell communication;cell differentiation;cell organization and biogenesis;cell proliferation;development;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane protein binding Pf00241 56320 ENSMUSG00000034675.17 Dbn1 13 0 High P62242 40S ribosomal protein S8 OS=Mus musculus OX=10090 GN=Rps8 PE=1 SV=2 0 36.595 50 8 50 8 208 24.2 10.32 1 1 382430.3877 652489.9233 32619.99219 263279.1353 5 6 1 6 metabolic process cytoplasm;cytosol;endoplasmic reticulum;membrane;nucleus;ribosome RNA binding;structural molecule activity Pf01201 20116; 100040298 ENSMUSG00000047675.15 Rps8; Gm15501 4; 7 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High P15331 Peripherin OS=Mus musculus OX=10090 GN=Prph PE=1 SV=2 0 29.189 22 12 50 9 475 54.2 5.52 721247.7563 129124.8301 29012.55957 57376.31934 8 4 2 3 cell organization and biogenesis membrane protein binding;structural molecule activity "Pf00038, Pf04732" 19132 Prph 15 0 High Q7M6Y3 Phosphatidylinositol-binding clathrin assembly protein OS=Mus musculus OX=10090 GN=Picalm PE=1 SV=1 0 76.307 40 17 50 7 660 71.5 7.91 89589.71094 486887.4956 83107.49219 580419.457 2 4 2 3 cell organization and biogenesis;cell proliferation;development;metabolic process;regulation of biological process;response to stimulus;transport cell surface;endosome;Golgi;membrane;nucleus protein binding "Pf01417, Pf07651" 233489 ENSMUSG00000039361.11 Picalm 7 Golgi Associated Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis 10 High Q8BP67 60S ribosomal protein L24 OS=Mus musculus OX=10090 GN=Rpl24 PE=1 SV=2 0 32.384 38 7 50 7 157 17.8 11.25 1 1 227236.8984 270699.6943 26312.79102 195394.2209 8 5 1 6 Met-loss [N-Term] cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process cytoplasm;membrane;ribosome protein binding;RNA binding;structural molecule activity Pf01246 68193 ENSMUSG00000098274.7 Rpl24 16 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High P70349 Histidine triad nucleotide-binding protein 1 OS=Mus musculus OX=10090 GN=Hint1 PE=1 SV=3 0 58.806 79 7 50 7 126 13.8 6.87 96352.94385 216231.3359 18890.54688 43000.31421 2 2 1 2 cell death;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;nucleus catalytic activity;nucleotide binding "Pf01230, Pf11969" 15254 ENSMUSG00000020267.6 Hint1 11 0 High Q3UQ44 Ras GTPase-activating-like protein IQGAP2 OS=Mus musculus OX=10090 GN=Iqgap2 PE=1 SV=2 0 59.462 21 22 49 21 1575 180.4 5.64 177438.9304 493241.2012 221570.3438 183940.6416 4 5 3 7 cell organization and biogenesis;regulation of biological process;response to stimulus cell surface;cytoplasm protein binding "Pf00307, Pf00616, Pf03836" 544963 ENSMUSG00000021676.9 Iqgap2 13 RHO GTPases activate IQGAPs; Neutrophil degranulation Regulation of actin cytoskeleton 1 High Q3UQN2 F-BAR domain only protein 2 OS=Mus musculus OX=10090 GN=Fcho2 PE=1 SV=1 0 67.739 24 13 49 13 809 88.7 6.89 20676.73975 5885.496582 681438.9805 60461.06763 2 1 2 3 cell organization and biogenesis;transport membrane protein binding "Pf00611, Pf10291" 218503 ENSMUSG00000041685.15 Fcho2 13 Cargo recognition for clathrin-mediated endocytosis 0 High Q91VH2 Sorting nexin-9 OS=Mus musculus OX=10090 GN=Snx9 PE=1 SV=1 0 57.067 35 15 49 15 595 66.5 5.52 115318.1919 163152.5723 19100.64844 182425.3032 4 3 1 5 cell division;cell organization and biogenesis;regulation of biological process;transport cytoplasm;cytosol;Golgi;membrane protein binding "Pf00018, Pf00787, Pf07653, Pf10456, Pf14604" 66616 ENSMUSG00000002365.9 Snx9 17 Clathrin-mediated endocytosis; Golgi Associated Vesicle Biogenesis 0 High Q8CG29 Myosin-1F-like protein OS=Mus musculus OX=10090 GN=Myo1f PE=1 SV=1 0 57.568 22 20 49 3 1098 125.1 9.17 160683.6807 166948.6533 7767.055664 81598.31812 4 4 1 5 defense response;regulation of biological process;response to stimulus;transport cytoskeleton catalytic activity;motor activity;nucleotide binding;protein binding "Pf00018, Pf00063, Pf06017, Pf07653, Pf14604" 17916 ENSMUSG00000024300.16 Myo1f 17 10 High P42567 Epidermal growth factor receptor substrate 15 OS=Mus musculus OX=10090 GN=Eps15 PE=1 SV=1 0 94.375 34 23 48 23 897 98.4 4.6 10263.27246 217930.1074 5703.953613 245782.7998 1 4 1 4 Met-loss+Acetyl [N-Term] cell organization and biogenesis;regulation of biological process;transport cytoplasm;cytosol;endosome;membrane metal ion binding;protein binding Pf12763 13858 ENSMUSG00000028552.13 Eps15 4 Cargo recognition for clathrin-mediated endocytosis; Negative regulation of MET activity; EGFR downregulation Endocytosis 0 High Q922D8 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Mus musculus OX=10090 GN=Mthfd1 PE=1 SV=4" 0 64.835 27 17 48 17 935 101.1 7.14 3343217.185 859410.0359 654190.5 2034051.397 6 5 1 5 metabolic process cytoplasm;cytosol;membrane;mitochondrion catalytic activity;nucleotide binding "Pf00763, Pf01268, Pf02882" 108156 ENSMUSG00000021048.7 Mthfd1 12 Metabolism of folate and pterines Metabolic pathways; One carbon pool by folate 0 High A0A0B4J1G0 Low affinity immunoglobulin gamma Fc region receptor IV OS=Mus musculus OX=10090 GN=Fcgr4 PE=1 SV=1 0 27.642 22 6 47 6 249 28.4 8.09 69770.01465 254122.9883 87064.45898 4 3 3 regulation of biological process;response to stimulus cell surface;membrane protein binding;receptor activity;signal transducer activity "Pf00047, Pf07679, Pf07686, Pf13895, Pf13927" 246256 ENSMUSG00000059089.4 Fcgr4 1 Role of phospholipids in phagocytosis; Post-translational modification: synthesis of GPI-anchored proteins; Neutrophil degranulation; Regulation of actin dynamics for phagocytic cup formation; FCGR activation Staphylococcus aureus infection; Tuberculosis; Osteoclast differentiation; Phagosome; Natural killer cell mediated cytotoxicity; Systemic lupus erythematosus; Leishmaniasis 0 High Q62193 Replication protein A 32 kDa subunit OS=Mus musculus OX=10090 GN=Rpa2 PE=1 SV=1 0 48.86 49 9 47 9 270 29.7 6.15 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus chromosome;nucleus DNA binding;protein binding Pf08784 19891 Rpa2 4 Meiotic Recombination; Mus musculus biological processes 0 High P61979 Heterogeneous nuclear ribonucleoprotein K OS=Mus musculus OX=10090 GN=Hnrnpk PE=1 SV=1 0 42.255 31 11 47 11 463 50.9 5.54 1 2 1 2 1154268.94 1873558.891 86544.90625 855132.1768 10 7 2 8 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus;spliceosomal complex DNA binding;protein binding;RNA binding "Pf00013, Pf08067, Pf13014, Pf13083" 15387 ENSMUSG00000021546.17 Hnrnpk 13 mRNA Splicing - Major Pathway Herpes simplex infection; MicroRNAs in cancer; Spliceosome; Viral carcinogenesis 0 High Q5RKN9 F-actin-capping protein subunit alpha OS=Mus musculus OX=10090 GN=Capza1 PE=1 SV=1 0 49.522 51 9 47 7 286 32.9 5.55 90870.0498 35954.67188 35247.96484 21769.97656 3 1 1 1 cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton;membrane protein binding Pf01267 12340 ENSMUSG00000070372.11 Capza1 3 Endocytosis 0 High G3X928 SEC23-interacting protein OS=Mus musculus OX=10090 GN=Sec23ip PE=1 SV=1 0 55.955 22 15 47 15 998 110.7 5.72 52474.85938 7833.487305 5 2 cell organization and biogenesis;transport endoplasmic reticulum;Golgi;membrane catalytic activity;metal ion binding;protein binding;RNA binding "Pf00536, Pf02862, Pf07647, Pf09770, Pf15279" 207352 ENSMUSG00000055319.8 Sec23ip 7 COPII (Coat Protein 2) Mediated Vesicle Transport 0 High P47963 60S ribosomal protein L13 OS=Mus musculus OX=10090 GN=Rpl13 PE=1 SV=3 0 25.553 29 7 46 7 211 24.3 11.55 211424.2507 218520.3438 60249.44141 3 1 1 metabolic process membrane;nucleus;ribosome RNA binding;structural molecule activity Pf01294 270106 ENSMUSG00000000740.12 Rpl13 8 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q9CQ71 Replication protein A 14 kDa subunit OS=Mus musculus OX=10090 GN=Rpa3 PE=1 SV=1 0 24.78 80 6 46 6 121 13.6 4.84 85534.96484 3123.342773 10694.51855 28660.59863 2 1 1 3 metabolic process;regulation of biological process;response to stimulus nucleus DNA binding Pf08661 68240 ENSMUSG00000012483.4 Rpa3 6 Termination of translesion DNA synthesis; Translesion synthesis by POLI; Meiotic Recombination; M/G1 Transition; Activation of ATR in response to replication stress; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion synthesis by POLK; Gap-filling DNA repair synthesis and ligation in TC-NER; Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Processing of DNA double-strand break ends; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); HDR through Single Strand Annealing (SSA); Regulation of HSF1-mediated heat shock response; Removal of the Flap Intermediate from the C-strand; Translesion Synthesis by POLH; Formation of Incision Complex in GG-NER; Gap-filling DNA repair synthesis and ligation in GG-NER; PCNA-Dependent Long Patch Base Excision Repair; Regulation of TP53 Activity through Phosphorylation; Presynaptic phase of homologous DNA pairing and strand exchange; Recognition of DNA damage by PCNA-containing replication complex; Dual incision in TC-NER; Fanconi Anemia Pathway; Activation of the pre-replicative complex; Translesion synthesis by REV1; G2/M DNA damage checkpoint; Mus musculus biological processes DNA replication; Homologous recombination; Nucleotide excision repair; Fanconi anemia pathway; Mismatch repair 0 High Q80VP1 Epsin-1 OS=Mus musculus OX=10090 GN=Epn1 PE=1 SV=3 0 73.22 32 12 46 12 575 60.2 4.81 87975.64258 130493.5977 93059.59277 49790.59766 2 2 2 2 regulation of biological process;response to stimulus;transport cytoplasm;cytosol;membrane;nucleus protein binding Pf01417 13854 ENSMUSG00000035203.16 Epn1 7 Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation Endocytosis 0 High Q6P5E4 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Mus musculus OX=10090 GN=Uggt1 PE=1 SV=4 0 61.287 18 24 46 24 1551 176.3 5.62 217480.8228 615185.6621 496817.4084 5 7 15 metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;organelle lumen catalytic activity;protein binding Pf06427 320011 ENSMUSG00000037470.14 Uggt1 1 ER Quality Control Compartment (ERQC) Protein processing in endoplasmic reticulum 0 High Q60737 Casein kinase II subunit alpha OS=Mus musculus OX=10090 GN=Csnk2a1 PE=1 SV=2 0 66.455 44 13 45 13 391 45.1 7.74 27772.57129 124043.5591 138304.5208 3 3 7 cell death;metabolic process;regulation of biological process;response to stimulus chromosome;cytoplasm;membrane;nucleus catalytic activity;enzyme regulator activity;nucleotide binding;protein binding "Pf00069, Pf01633, Pf01636, Pf07714" 12995 ENSMUSG00000101523.1; ENSMUSG00000074698.10 Csnk2a1 2; 1 WNT mediated activation of DVL; Regulation of TP53 Activity through Phosphorylation; Synthesis of PC; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Condensation of Prometaphase Chromosomes; Receptor Mediated Mitophagy; Regulation of PTEN stability and activity; Signal transduction by L1; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Herpes simplex infection; Wnt signaling pathway; Epstein-Barr virus infection; Adherens junction; Ribosome biogenesis in eukaryotes; NF-kappa B signaling pathway; Tight junction; Measles 0 High Q9CQM8 60S ribosomal protein L21 OS=Mus musculus OX=10090 GN=Rpl21 PE=1 SV=1 0 26.081 26 4 45 4 160 18.6 10.49 1 1 233853.743 428829.9063 129313.7285 259740.4731 3 2 2 2 metabolic process membrane;ribosome protein binding;RNA binding;structural molecule activity Pf01157 19933; 676253; 100503563; 675278 ENSMUSG00000041453.12 Rpl21; Gm14648; Gm10240; Rpl21-ps15 5; X; 15 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q9Z2I8 "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial OS=Mus musculus OX=10090 GN=Suclg2 PE=1 SV=3" 0 50.898 41 13 45 13 433 46.8 7.02 231588.7905 167756.6807 92524.03711 300760.918 6 5 2 6 metabolic process membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00549, Pf01071, Pf08442, Pf13549" 20917 ENSMUSG00000061838.7 Suclg2 6 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Propanoate metabolism; Carbon metabolism 0 High Z4YJW0 ER membrane protein complex subunit 1 OS=Mus musculus OX=10090 GN=Emc1 PE=1 SV=1 0 81.431 28 20 45 20 997 111.5 7.43 17189.93945 16261.84961 161915.2227 1 2 6 "Pf07774, Pf13360" ENSMUSG00000078517.11 4 0 High Q9R0H0 Peroxisomal acyl-coenzyme A oxidase 1 OS=Mus musculus OX=10090 GN=Acox1 PE=1 SV=5 0 60.748 30 14 45 14 661 74.6 8.48 49296.49463 75633.23145 42141.74609 30972.41504 4 3 1 3 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;membrane;mitochondrion;nucleus catalytic activity;nucleotide binding;protein binding "Pf01756, Pf02770, Pf14749" 11430 ENSMUSG00000020777.16 Acox1 11 Beta-oxidation of very long chain fatty acids; alpha-linolenic acid (ALA) metabolism PPAR signaling pathway; Fatty acid metabolism; Metabolic pathways; Fatty acid degradation; alpha-Linolenic acid metabolism; cAMP signaling pathway; Biosynthesis of unsaturated fatty acids; Peroxisome 0 High E9PWE8 Dihydropyrimidinase-related protein 3 OS=Mus musculus OX=10090 GN=Dpysl3 PE=1 SV=1 0 48.592 29 13 44 10 683 73.8 6.46 98778.81299 491410.6252 159004.4219 82321.57153 3 3 1 4 cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytosol catalytic activity;protein binding "Pf01979, Pf04909, Pf13147, Pf13594" 22240 ENSMUSG00000024501.19 Dpysl3 18 3 High Q8K169 UDP-glucuronosyltransferase OS=Mus musculus OX=10090 GN=Ugt2b5 PE=1 SV=1 0 62.411 34 12 44 9 530 60.8 7.87 49483.62402 8110.552734 2 1 metabolic process endoplasmic reticulum;membrane catalytic activity "Pf00201, Pf04101, Pf13528" 22238 ENSMUSG00000054630.7 Ugt2b5 5 Steroid hormone biosynthesis; Drug metabolism - cytochrome P450; Retinol metabolism; Metabolic pathways; Drug metabolism - other enzymes; Ascorbate and aldarate metabolism; Chemical carcinogenesis; Porphyrin and chlorophyll metabolism; Pentose and glucuronate interconversions; Metabolism of xenobiotics by cytochrome P450 1 High Q99LF4 RNA-splicing ligase RtcB homolog OS=Mus musculus OX=10090 GN=Rtcb PE=1 SV=1 0 43.874 31 11 44 11 505 55.2 7.23 1 1 177758.6819 667980.1875 111017.5928 311672.4287 7 5 2 7 metabolic process cytoplasm;cytosol;membrane;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding;RNA binding Pf01139 28088 ENSMUSG00000001783.3 D10Wsu52e; Rtcb 10 0 High Q9CPR4 60S ribosomal protein L17 OS=Mus musculus OX=10090 GN=Rpl17 PE=1 SV=3 0 36.782 47 7 44 7 184 21.4 10.18 78393.99805 36998.54492 308525.8242 128222.7871 4 2 2 3 metabolic process;regulation of biological process nucleus;ribosome protein binding;RNA binding;structural molecule activity Pf00237 319195 Rpl17 18 0 High Q6IRU5 Clathrin light chain B OS=Mus musculus OX=10090 GN=Cltb PE=1 SV=1 0 26.776 23 8 44 8 229 25.2 4.63 7757.552246 1 transport cytosol;membrane protein binding;structural molecule activity Pf01086 74325 ENSMUSG00000047547.14 Cltb 13 "WNT5A-dependent internalization of FZD4; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Lysosome Vesicle Biogenesis; Formation of annular gap junctions; Cargo recognition for clathrin-mediated endocytosis" Endocytosis; Endocrine and other factor-regulated calcium reabsorption; Lysosome; Huntington's disease; Synaptic vesicle cycle; Bacterial invasion of epithelial cells 0 High Q8C2Q7 Heterogeneous nuclear ribonucleoprotein H OS=Mus musculus OX=10090 GN=Hnrnph1 PE=1 SV=1 0 48.352 30 10 44 4 472 51.2 6.8 1 1 1 1 1 1 733459.0591 907225.959 1008345.137 618237.0938 7 5 2 7 Acetyl [N-Term] metabolic process;regulation of biological process cytosol;membrane;nucleus;spliceosomal complex protein binding;RNA binding "Pf00076, Pf08080, Pf14259" 59013 ENSMUSG00000007850.16 Hnrnph1 11 8 High P62889 60S ribosomal protein L30 OS=Mus musculus OX=10090 GN=Rpl30 PE=1 SV=2 0 27.202 51 4 44 4 115 12.8 9.63 196040.4736 144641.3184 18388.38477 184257.4063 4 4 1 3 defense response;metabolic process;response to stimulus membrane;nucleus;ribosome RNA binding;structural molecule activity Pf01248 19946; 667779; 666899 ENSMUSG00000058600.13 Rpl30; Rpl30-ps8; Gm12191 15; 12; 11 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High A0A0A6YX66 Immunoglobulin heavy variable V1-20 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-20 PE=4 SV=1 0 26.316 38 4 44 3 117 13.1 8.43 1 1 3 1 415733.4688 235728.0049 11966.3291 220403.2534 4 3 1 3 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000095761.6 LOC672918 12 0 High A0A075B5U7 Immunoglobulin heavy variable 1-22 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-22 PE=1 SV=1 0 24.082 41 5 44 3 117 13 8.76 3 3 7 3 5159601.513 9382070.383 2455406.976 816168.3774 4 4 2 3 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000094561.1 LOC673196 12 1 High A0A140T8M5 Immunoglobulin kappa variable 6-15 (Fragment) OS=Mus musculus OX=10090 GN=Igkv6-15 PE=1 SV=2 0 27.668 40 4 43 2 115 12.7 4.96 4 3 8 6 2261968.5 2241979.016 175952.2109 422151.8477 3 3 2 3 "Pf00047, Pf07679, Pf07686" 108022 ENSMUSG00000094797.1 Igkv6-15 6 1 High Q8BJL9 UDP-glucuronosyltransferase OS=Mus musculus OX=10090 GN=Ugt2b35 PE=1 SV=1 0 72.363 37 16 43 14 529 60.4 8.1 138278.0654 230188.2578 91399.02222 202974.042 3 3 2 7 metabolic process membrane catalytic activity "Pf00201, Pf04101" 243085 ENSMUSG00000035811.10 Ugt2b35 5 Steroid hormone biosynthesis; Drug metabolism - cytochrome P450; Retinol metabolism; Metabolic pathways; Drug metabolism - other enzymes; Ascorbate and aldarate metabolism; Chemical carcinogenesis; Porphyrin and chlorophyll metabolism; Pentose and glucuronate interconversions; Metabolism of xenobiotics by cytochrome P450 2 High P70248 Unconventional myosin-If OS=Mus musculus OX=10090 GN=Myo1f PE=1 SV=1 0 49.345 20 18 43 1 1099 125.9 8.92 17635.3125 4097.149414 1 1 defense response;regulation of biological process;response to stimulus;transport cytoskeleton catalytic activity;motor activity;nucleotide binding;protein binding "Pf00018, Pf00063, Pf06017, Pf07653, Pf14604" 17916 Myo1f 17 0 High Q9D136 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 OS=Mus musculus OX=10090 GN=Ogfod3 PE=2 SV=1 0 44.407 33 9 43 9 315 35.4 6.74 58782.89844 273094.2969 1 2 metabolic process membrane catalytic activity;metal ion binding Pf13640 66179 ENSMUSG00000025169.6 1110031I02Rik; Ogfod3 11 0 High Q9R0Q6 Actin-related protein 2/3 complex subunit 1A OS=Mus musculus OX=10090 GN=Arpc1a PE=1 SV=1 0 79.301 42 12 43 11 370 41.6 8.18 188486.3672 329782.6133 179269.125 123332.584 3 2 1 2 Met-loss+Acetyl [N-Term] cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton protein binding Pf00400 56443 ENSMUSG00000029621.14 Arpc1a 5 RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling; Regulation of actin dynamics for phagocytic cup formation Endocytosis; Regulation of actin cytoskeleton; Salmonella infection; Fc gamma R-mediated phagocytosis; Bacterial invasion of epithelial cells 0 High Q9WV68 "Peroxisomal 2,4-dienoyl-CoA reductase OS=Mus musculus OX=10090 GN=Decr2 PE=1 SV=1" 0 43.098 36 10 43 10 292 31.3 8.81 258547.959 39864.40942 96877.12695 166750.5161 2 2 2 3 metabolic process membrane catalytic activity;protein binding "Pf00106, Pf08659, Pf13561" 26378 ENSMUSG00000036775.12 Decr2 17 Beta-oxidation of very long chain fatty acids Peroxisome 0 High E9Q2E4 HECT domain E3 ubiquitin protein ligase 4 OS=Mus musculus OX=10090 GN=Hectd4 PE=1 SV=2 0 92.11 10 30 42 30 4418 483.8 6.06 235883.4453 279018.6289 195937.2759 116960.1797 6 4 6 5 Met-loss+Acetyl [N-Term] metabolic process cytoplasm catalytic activity;protein binding "Pf00622, Pf00632" 269700 ENSMUSG00000042744.16 Gm15800; Hectd4 5 0 High P09405 Nucleolin OS=Mus musculus OX=10090 GN=Ncl PE=1 SV=2 0 27.628 22 11 42 11 707 76.7 4.75 131571 169756.8438 64808.79297 74924.57129 2 2 2 2 regulation of biological process;response to stimulus;transport cell surface;cytoplasm;membrane;nucleus DNA binding;metal ion binding;protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 17975 ENSMUSG00000026234.12 Ncl 1 Major pathway of rRNA processing in the nucleolus and cytosol 0 High A2AVJ7 Ribosome-binding protein 1 OS=Mus musculus OX=10090 GN=Rrbp1 PE=1 SV=1 0 60.713 27 17 42 17 1464 158.3 9.19 103039.082 331601.3223 167796.8535 151875.8218 7 6 4 7 cell differentiation;metabolic process;regulation of biological process;transport endoplasmic reticulum;membrane;ribosome protein binding;receptor activity;RNA binding;structural molecule activity "Pf00038, Pf03276, Pf03962, Pf04111, Pf04156, Pf05104, Pf08317, Pf09606, Pf09726, Pf10186, Pf12128, Pf13779" 81910 ENSMUSG00000027422.15 Rrbp1 2 Protein processing in endoplasmic reticulum 0 High Q7TMK6 Protein Hook homolog 2 OS=Mus musculus OX=10090 GN=Hook2 PE=1 SV=3 0 74.733 38 18 42 18 716 83.3 5.43 303244.855 4253092.734 23387.54492 694466.5527 5 4 1 2 cell organization and biogenesis;transport cytoplasm;cytoskeleton;cytosol protein binding Pf05622 170833 ENSMUSG00000052566.8 Hook2 8 0 High Q9D5V5 Cullin-5 OS=Mus musculus OX=10090 GN=Cul5 PE=1 SV=3 0 31.932 20 15 42 15 780 90.9 7.81 1194439.778 2622825.41 1044714.188 801460.2888 9 2 1 2 cellular component movement;cellular homeostasis;metabolic process;response to stimulus cytoplasm;membrane;nucleus catalytic activity;protein binding "Pf00888, Pf10557" 75717 Cul5 9 Ubiquitin mediated proteolysis 0 High A0A140LHQ8 Phosphatidylinositol-binding clathrin assembly protein (Fragment) OS=Mus musculus OX=10090 GN=Picalm PE=1 SV=1 0 50.351 34 11 42 1 531 57 7.59 cell organization and biogenesis;cell proliferation;development;metabolic process;regulation of biological process;response to stimulus;transport cell surface;endosome;Golgi;membrane;nucleus protein binding Pf07651 233489 ENSMUSG00000039361.11 Picalm 7 0 High P97872 Dimethylaniline monooxygenase [N-oxide-forming] 5 OS=Mus musculus OX=10090 GN=Fmo5 PE=1 SV=4 0 50.663 37 13 42 13 533 60 8.73 150184.6072 31450.7251 8515.902344 117383.0764 6 3 1 6 metabolic process cytosol;endoplasmic reticulum;membrane catalytic activity;nucleotide binding "Pf00743, Pf07992, Pf13450, Pf13454, Pf13738" 14263 ENSMUSG00000028088.14 Fmo5 3 Drug metabolism - cytochrome P450 0 High F8WJ41 40S ribosomal protein S15a (Fragment) OS=Mus musculus OX=10090 GN=Rps15a PE=1 SV=1 0 23.01 53 6 42 6 108 12.3 10.15 123772.605 211183.4587 60440.89941 207233.792 6 6 2 6 metabolic process mitochondrion;ribosome structural molecule activity Pf00410 ENSMUSG00000008683.16 7 0 High Q9CPW4 Actin-related protein 2/3 complex subunit 5 OS=Mus musculus OX=10090 GN=Arpc5 PE=1 SV=3 0 36.016 44 6 41 6 151 16.3 5.67 48585.11597 125862.9609 27407.15234 33512.16113 2 3 1 2 cell organization and biogenesis;cellular component movement;regulation of biological process cytoplasm;cytoskeleton;endosome protein binding;structural molecule activity Pf04699 67771 ENSMUSG00000008475.13 Arpc5 1 RHO GTPases Activate WASPs and WAVEs; Neutrophil degranulation; Clathrin-mediated endocytosis; EPHB-mediated forward signaling; Regulation of actin dynamics for phagocytic cup formation Endocytosis; Regulation of actin cytoskeleton; Salmonella infection; Fc gamma R-mediated phagocytosis; Bacterial invasion of epithelial cells 0 High A0A1L1SQA8 40S ribosomal protein S25 OS=Mus musculus OX=10090 GN=Rps25 PE=1 SV=1 0 16.674 32 4 41 4 93 10.3 9.99 84389.34766 457886.916 116027.8789 148333.1123 2 4 2 3 Pf03297 ENSMUSG00000009927.9 9 0 High Q8BTM8 Filamin-A OS=Mus musculus OX=10090 GN=Flna PE=1 SV=5 0 73.113 15 24 41 24 2647 281 6.04 371722.5615 277459.7212 16962.79688 47853.7334 12 8 1 3 cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;membrane;nucleus protein binding;RNA binding;signal transducer activity "Pf00307, Pf00630" 192176 ENSMUSG00000031328.15 Flna X RHO GTPases activate PAKs; Cell-extracellular matrix interactions; Platelet degranulation ; GP1b-IX-V activation signalling 0 High P60335 Poly(rC)-binding protein 1 OS=Mus musculus OX=10090 GN=Pcbp1 PE=1 SV=1 0 24.292 27 6 41 4 356 37.5 7.09 324580.2422 381482.459 27230.88281 140782.3516 4 5 1 3 metabolic process;regulation of biological process cytoplasm;cytosol;membrane;nucleus DNA binding;protein binding;RNA binding;translation regulator activity "Pf00013, Pf13014" 23983 ENSMUSG00000051695.6 Pcbp1 6 mRNA Splicing - Major Pathway Spliceosome 2 High Q9CZM2 60S ribosomal protein L15 OS=Mus musculus OX=10090 GN=Rpl15 PE=1 SV=4 0 40.373 41 9 41 9 204 24.1 11.62 117976.668 153475.292 46468.76172 199357.082 3 3 2 4 metabolic process membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity Pf00827 66480 ENSMUSG00000012405.15 Rpl15 14 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q9QXF8 Glycine N-methyltransferase OS=Mus musculus OX=10090 GN=Gnmt PE=1 SV=3 0 43.939 41 9 41 9 293 32.7 7.44 191562.2158 85964.21875 37255.19141 4637.128418 3 3 1 1 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;cytosol catalytic activity "Pf01209, Pf05401, Pf08241, Pf08242, Pf12847, Pf13489, Pf13649, Pf13659, Pf13847" 14711 ENSMUSG00000002769.8 Gnmt 17 Glyoxylate metabolism and glycine degradation "Glycine, serine and threonine metabolism" 0 High P18760 Cofilin-1 OS=Mus musculus OX=10090 GN=Cfl1 PE=1 SV=3 0 32.73 66 9 41 6 166 18.5 8.09 100391.6411 172448.9492 38845.55127 3 3 3 Met-loss+Acetyl [N-Term] cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;extracellular;membrane;nucleus protein binding Pf00241 12631 ENSMUSG00000056201.7 Cfl1 19 Regulation of actin cytoskeleton; Axon guidance; Pertussis; Fc gamma R-mediated phagocytosis 3 High Q91Z96 BMP-2-inducible protein kinase OS=Mus musculus OX=10090 GN=Bmp2k PE=1 SV=1 0 69.013 27 19 41 19 1138 126.1 6.8 319584.6692 370058.2759 940421.5173 727708.6082 8 5 5 9 metabolic process;regulation of biological process cytoplasm;nucleus catalytic activity;enzyme regulator activity;nucleotide binding;protein binding "Pf00069, Pf07714, Pf15282" 140780 ENSMUSG00000034663.13 Bmp2k 5 Transcriptional misregulation in cancer 0 High Q8BG05 Heterogeneous nuclear ribonucleoprotein A3 OS=Mus musculus OX=10090 GN=Hnrnpa3 PE=1 SV=1 0 48.921 29 12 41 12 379 39.6 9.01 1 1 1 1 670165.207 902330.1182 32223.26172 492995.8035 8 7 1 8 metabolic process;transport cytoplasm;nucleus;spliceosomal complex RNA binding;transporter activity "Pf00076, Pf13893, Pf14259" 229279 ENSMUSG00000059005.13 Hnrnpa3 2 Spliceosome 0 High P62908 40S ribosomal protein S3 OS=Mus musculus OX=10090 GN=Rps3 PE=1 SV=1 0 30.375 42 9 41 9 243 26.7 9.66 57592.38086 285469.0645 19586.39063 330274.0625 3 3 1 5 cell death;cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;endoplasmic reticulum;membrane;mitochondrion;nucleus;organelle lumen;ribosome catalytic activity;DNA binding;protein binding;RNA binding;structural molecule activity "Pf00189, Pf07650" 27050 ENSMUSG00000030744.13 Rps3 7 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High K9J7B2 UDP-glucuronosyltransferase OS=Mus musculus OX=10090 GN=Ugt1a6b PE=1 SV=1 0 56.633 36 13 41 2 531 60.5 8.69 metabolic process endoplasmic reticulum;membrane catalytic activity;protein binding "Pf00201, Pf04101" 394435 ENSMUSG00000090145.7 Ugt1a6b 1 Glucuronidation Steroid hormone biosynthesis; Drug metabolism - cytochrome P450; Retinol metabolism; Metabolic pathways; Drug metabolism - other enzymes; Ascorbate and aldarate metabolism; Chemical carcinogenesis; Porphyrin and chlorophyll metabolism; Pentose and glucuronate interconversions; Metabolism of xenobiotics by cytochrome P450 0 High B1ARA3 60S ribosomal protein L26 (Fragment) OS=Mus musculus OX=10090 GN=Rpl26 PE=1 SV=1 0 13.287 47 7 41 7 103 12.2 10.92 78845.85449 41767.75 20159.26758 4 1 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;ribosome protein binding;RNA binding;structural molecule activity Pf00467 19941 ENSMUSG00000060938.14 Rpl26 11 0 High Q8VC30 Triokinase/FMN cyclase OS=Mus musculus OX=10090 GN=Tkfc PE=1 SV=1 0 63.217 45 16 41 16 578 59.7 6.92 6142.961426 33653.65918 93820.47656 1 3 1 metabolic process;regulation of biological process nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf02733, Pf02734" 225913 ENSMUSG00000034371.8 Dak; Tkfc 19 Fructose catabolism Metabolic pathways; RIG-I-like receptor signaling pathway; Carbon metabolism; Glycerolipid metabolism; Fructose and mannose metabolism 0 High Q80X19 Collagen alpha-1(XIV) chain OS=Mus musculus OX=10090 GN=Col14a1 PE=1 SV=2 0 56.694 15 18 41 18 1797 192.9 5.1 2 1 2 1 1260894.353 1304820.154 161334.0469 167236.5217 16 10 4 7 cell organization and biogenesis;regulation of biological process extracellular protein binding;RNA binding "Pf00041, Pf00092, Pf01391, Pf13519" 12818 ENSMUSG00000022371.15 Col14a1 15 Collagen chain trimerization; Assembly of collagen fibrils and other multimeric structures 0 High Q91YW3 DnaJ homolog subfamily C member 3 OS=Mus musculus OX=10090 GN=Dnajc3 PE=1 SV=1 0 82.556 56 20 40 20 504 57.4 5.85 325731.5544 913899.9814 134526.9668 475212.5098 6 4 3 7 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;endoplasmic reticulum;membrane;organelle lumen enzyme regulator activity;protein binding "Pf00226, Pf00515, Pf13371, Pf13414, Pf13424, Pf14559" 100037258 ENSMUSG00000022136.7 Dnajc3 14 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Neutrophil degranulation; Post-translational protein phosphorylation Influenza A; Protein processing in endoplasmic reticulum 0 High Q64435 UDP-glucuronosyltransferase 1-6 OS=Mus musculus OX=10090 GN=Ugt1a6 PE=1 SV=1 0 60.655 41 14 40 3 531 60.4 8.62 38765.33203 126377.6064 190440.7949 245403.0186 1 2 3 3 metabolic process endoplasmic reticulum;membrane catalytic activity;protein binding "Pf00201, Pf04101" 94284 ENSMUSG00000090124.7; ENSMUSG00000054545.17 Ugt1a6a 1 Glucuronidation Steroid hormone biosynthesis; Drug metabolism - cytochrome P450; Retinol metabolism; Metabolic pathways; Drug metabolism - other enzymes; Ascorbate and aldarate metabolism; Chemical carcinogenesis; Porphyrin and chlorophyll metabolism; Pentose and glucuronate interconversions; Metabolism of xenobiotics by cytochrome P450 3 High O55022 Membrane-associated progesterone receptor component 1 OS=Mus musculus OX=10090 GN=Pgrmc1 PE=1 SV=4 0 29.348 41 8 40 8 195 21.7 4.7 9313.791748 26352.13867 2 3 regulation of biological process;response to stimulus endoplasmic reticulum;membrane Pf00173 53328 ENSMUSG00000006373.10 Pgrmc1 X Neutrophil degranulation 0 High P14115 60S ribosomal protein L27a OS=Mus musculus OX=10090 GN=Rpl27a PE=1 SV=5 0 18.212 37 5 40 5 148 16.6 11.12 1 2 1 2 113780.9609 318565.3984 18384.48633 96235.66797 3 2 1 2 metabolic process cytosol;endoplasmic reticulum;membrane;ribosome RNA binding;structural molecule activity Pf00828 26451 ENSMUSG00000046364.14 Rpl27a 7 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q9CR57 60S ribosomal protein L14 OS=Mus musculus OX=10090 GN=Rpl14 PE=1 SV=3 0 23.155 24 5 40 5 217 23.5 11.02 112789.627 228136.1719 45006.79297 144000.6563 2 1 1 2 metabolic process membrane;ribosome protein binding;RNA binding;structural molecule activity Pf01929 67115 ENSMUSG00000025794.9 Rpl14 9 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q9Z2X1 Heterogeneous nuclear ribonucleoprotein F OS=Mus musculus OX=10090 GN=Hnrnpf PE=1 SV=3 0 46.342 22 6 40 4 415 45.7 5.49 1 1 1 1 1 1 46500.67432 127330.6406 110671.5625 106700.5781 3 1 1 1 metabolic process;regulation of biological process cytosol;membrane;nucleus;spliceosomal complex protein binding;RNA binding "Pf00076, Pf08080, Pf14259" 98758 ENSMUSG00000042079.13 Hnrnpf 6 mRNA Splicing - Major Pathway; FGFR2 alternative splicing 0 High Q8VIJ6 "Splicing factor, proline- and glutamine-rich OS=Mus musculus OX=10090 GN=Sfpq PE=1 SV=1" 0 36.148 20 11 40 10 699 75.4 9.44 453427.9922 294560.125 125812.7109 130704.4609 6 3 2 3 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus chromosome;cytoplasm;nucleus DNA binding;protein binding;RNA binding "Pf00076, Pf08075, Pf13893, Pf14259" 71514 ENSMUSG00000028820.13 Sfpq 4 PTK6 Regulates Proteins Involved in RNA Processing 1 High O35130 Ribosomal RNA small subunit methyltransferase NEP1 OS=Mus musculus OX=10090 GN=Emg1 PE=1 SV=1 0 46.066 48 10 39 10 244 27 8.91 45306.30078 2 cell organization and biogenesis;metabolic process nucleus catalytic activity;RNA binding Pf03587 14791 ENSMUSG00000004268.11 Emg1 6 Major pathway of rRNA processing in the nucleolus and cytosol Ribosome biogenesis in eukaryotes 0 High Q61838 Pregnancy zone protein OS=Mus musculus OX=10090 GN=Pzp PE=1 SV=3 0 54.475 16 16 39 16 1495 165.7 6.68 1 1 359215.9023 208779.7056 38447.28906 5869.707031 7 2 1 1 regulation of biological process extracellular enzyme regulator activity;protein binding "Pf00207, Pf01835, Pf07677, Pf07678, Pf07703, Pf10569, Pf11974, Pf13249" 11287 ENSMUSG00000030359.14 Pzp 6 0 High Q6ZWN5 40S ribosomal protein S9 OS=Mus musculus OX=10090 GN=Rps9 PE=1 SV=3 0 19.778 37 9 39 9 194 22.6 10.65 141256.4336 245100.6777 42776.47266 144331.4395 5 5 2 4 metabolic process;regulation of biological process cytoplasm;membrane;nucleus;ribosome RNA binding;structural molecule activity;translation regulator activity "Pf00163, Pf01479" 76846 ENSMUSG00000006333.14 Rps9 7 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High P31001 Desmin OS=Mus musculus OX=10090 GN=Des PE=1 SV=3 0 52.997 26 12 39 7 469 53.5 5.27 1 3 1 4 123261.1963 3 cell organization and biogenesis cytoplasm;cytoskeleton;membrane;nucleus protein binding;structural molecule activity "Pf00038, Pf03962, Pf04732" 13346 ENSMUSG00000026208.9 Des 1 Striated Muscle Contraction Hypertrophic cardiomyopathy (HCM); Arrhythmogenic right ventricular cardiomyopathy (ARVC); Dilated cardiomyopathy 0 High Q9JKR6 Hypoxia up-regulated protein 1 OS=Mus musculus OX=10090 GN=Hyou1 PE=1 SV=1 0 48.276 21 14 39 14 999 111.1 5.19 59012.3667 61319.92285 34410.44238 361152.0537 3 3 2 10 regulation of biological process;response to stimulus;transport endoplasmic reticulum;extracellular;membrane;organelle lumen nucleotide binding Pf00012 12282 ENSMUSG00000032115.14 Hyou1 9 Protein processing in endoplasmic reticulum 0 High P11983 T-complex protein 1 subunit alpha OS=Mus musculus OX=10090 GN=Tcp1 PE=1 SV=3 0 34.61 25 11 39 11 556 60.4 6.16 143868.2727 46789.69531 24391.82813 50476.78589 3 1 1 5 Acetyl [N-Term] metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;Golgi nucleotide binding;protein binding;RNA binding Pf00118 21454 ENSMUSG00000068039.12 Tcp1 17 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Association of TriC/CCT with target proteins during biosynthesis 0 High Q9R112 "Sulfide:quinone oxidoreductase, mitochondrial OS=Mus musculus OX=10090 GN=Sqor PE=1 SV=3" 0 61.415 41 17 39 17 450 50.3 9.09 1402763.547 2652141.532 946263.9395 1346612.587 7 5 3 9 metabolic process membrane;mitochondrion catalytic activity "Pf07992, Pf13738" 59010 ENSMUSG00000005803.14 Sqrdl; Sqor 2 Sulfide oxidation to sulfate Sulfur metabolism 0 High Q99K67 "Alpha-aminoadipic semialdehyde synthase, mitochondrial OS=Mus musculus OX=10090 GN=Aass PE=1 SV=1" 0 51.12 22 14 38 14 926 102.9 6.87 200282.6006 133499.9297 10725.8584 3 2 1 metabolic process mitochondrion catalytic activity "Pf01262, Pf03435, Pf05222" 30956 ENSMUSG00000029695.13 Aass 6 Lysine catabolism Metabolic pathways; Lysine degradation 0 High P14824 Annexin A6 OS=Mus musculus OX=10090 GN=Anxa6 PE=1 SV=3 0 87.81 41 22 38 22 673 75.8 5.5 484052.4099 103230.9297 31205.85352 300311.2637 7 1 1 2 cell organization and biogenesis;cellular homeostasis;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;membrane;mitochondrion;nucleus metal ion binding;nucleotide binding;protein binding;transporter activity Pf00191 11749 ENSMUSG00000018340.13 Anxa6 11 0 High Q8BXQ2 GPI transamidase component PIG-T OS=Mus musculus OX=10090 GN=Pigt PE=1 SV=2 0 45.044 20 11 38 11 582 65.7 8.4 29686.89063 6329.939941 52903.29297 135176.7236 1 1 1 4 cell death;cell differentiation;metabolic process cytoplasm;endoplasmic reticulum;membrane catalytic activity Pf04113 78928 ENSMUSG00000017721.15 Pigt 2 Attachment of GPI anchor to uPAR Glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Metabolic pathways 0 High Q9EP89 "Serine beta-lactamase-like protein LACTB, mitochondrial OS=Mus musculus OX=10090 GN=Lactb PE=1 SV=1" 0 59.334 32 14 38 14 551 60.7 8.9 150400.0659 299024.7734 1252625.631 91428.43042 8 6 3 5 metabolic process;regulation of biological process cytosol;membrane;mitochondrion catalytic activity;protein binding Pf00144 80907 ENSMUSG00000032370.8 Lactb 9 0 High P14131 40S ribosomal protein S16 OS=Mus musculus OX=10090 GN=Rps16 PE=1 SV=4 0 24.648 58 11 38 11 146 16.4 10.21 81598.64355 63157.19141 15989.13672 84854.24414 5 3 1 3 Met-loss [N-Term] metabolic process membrane;ribosome RNA binding;structural molecule activity Pf00380 100039355; 20055 ENSMUSG00000037563.15 Rps16-ps2; Rps16 5; 7 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High Q6GT24 Peroxiredoxin-6 OS=Mus musculus OX=10090 GN=Prdx6 PE=1 SV=1 0 27.112 51 9 38 9 224 24.8 6.37 2 1 2 1 500373.3652 315480.5273 26962.88818 234107.0549 8 4 2 5 Met-loss [N-Term] cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus;vacuole antioxidant activity;catalytic activity;protein binding "Pf00578, Pf08534, Pf10417" 11758 ENSMUSG00000026701.15 Prdx6 1 Neutrophil degranulation; Detoxification of Reactive Oxygen Species Metabolic pathways 0 High P97457 "Myosin regulatory light chain 2, skeletal muscle isoform OS=Mus musculus OX=10090 GN=Mylpf PE=1 SV=3" 0 83.148 72 15 38 15 169 18.9 4.92 233721.2808 141286.4004 10308.37427 7 3 2 response to stimulus membrane metal ion binding;structural molecule activity "Pf00036, Pf13405, Pf13833" 17907 ENSMUSG00000030672.12 Mylpf 7 Smooth Muscle Contraction Leukocyte transendothelial migration; Regulation of actin cytoskeleton; Focal adhesion; Tight junction 0 High E9QAT4 Protein transport protein Sec16A OS=Mus musculus OX=10090 GN=Sec16a PE=1 SV=1 0 51.36 13 19 38 19 2357 254 5.81 96556.96777 88356.22607 158021.2026 75949.69141 4 3 4 3 cell organization and biogenesis;transport cytosol;endoplasmic reticulum;Golgi;membrane catalytic activity "Pf10697, Pf12931, Pf12932" 227648 ENSMUSG00000026924.17 Sec16a 2 COPII (Coat Protein 2) Mediated Vesicle Transport 0 High A0A075B664 Immunoglobulin lambda variable 2 OS=Mus musculus OX=10090 GN=Iglv2 PE=1 SV=1 0 21.644 36 2 37 1 116 12.2 5.74 1 2 7 6 4739406.875 1777479.375 89610.44531 1 1 1 Pf07686 ENSMUSG00000076940.3 16 0 High D3Z2H7 Catenin delta-1 OS=Mus musculus OX=10090 GN=Ctnnd1 PE=1 SV=1 0 45.818 31 15 37 15 609 67.9 8.13 53205.32495 12911.50879 4 1 protein binding Pf00514 ENSMUSG00000034101.14 2 0 High Q8VD75 Huntingtin-interacting protein 1 OS=Mus musculus OX=10090 GN=Hip1 PE=1 SV=2 0 66.42 21 16 37 16 1029 115.1 5.43 117955.5532 70642.10352 149795.9473 108864.2478 6 4 2 6 cell death;cell differentiation;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;Golgi;membrane;nucleus catalytic activity;motor activity;protein binding;structural molecule activity "Pf00038, Pf01417, Pf01576, Pf01608, Pf06705, Pf07651, Pf07888, Pf09730, Pf12128, Pf13851, Pf14362" 215114 ENSMUSG00000039959.13 Hip1 5 Clathrin-mediated endocytosis Huntington's disease 0 High Q91VS7 Microsomal glutathione S-transferase 1 OS=Mus musculus OX=10090 GN=Mgst1 PE=1 SV=3 0 32.053 24 4 37 4 155 17.5 9.66 cell organization and biogenesis;metabolic process;response to stimulus endoplasmic reticulum;membrane;mitochondrion;nucleus antioxidant activity;catalytic activity;protein binding Pf01124 56615 ENSMUSG00000008540.11 Mgst1 6 Glutathione conjugation; Aflatoxin activation and detoxification; Neutrophil degranulation Glutathione metabolism; Platinum drug resistance; Drug metabolism - cytochrome P450; Chemical carcinogenesis; Metabolism of xenobiotics by cytochrome P450 0 High P62281 40S ribosomal protein S11 OS=Mus musculus OX=10090 GN=Rps11 PE=1 SV=3 0 19.536 41 6 37 6 158 18.4 10.3 1 1 1 1 284481.1504 375620.5859 213804.4043 5 3 3 Met-loss+Acetyl [N-Term] cell differentiation;metabolic process cytoplasm;membrane;ribosome RNA binding;structural molecule activity Pf00366 27207 ENSMUSG00000003429.11 Rps11 7 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High B1AV77 Aldehyde dehydrogenase OS=Mus musculus OX=10090 GN=Aldh3a2 PE=1 SV=1 0 52.772 34 14 37 14 487 54.3 8.48 48024.19238 451378.8027 605784.1563 170406.7915 3 5 5 5 metabolic process;response to stimulus cytosol;endoplasmic reticulum;membrane;mitochondrion;nucleus catalytic activity Pf00171 11671 ENSMUSG00000010025.19 Aldh3a2 11 0 High Q91YR1 Twinfilin-1 OS=Mus musculus OX=10090 GN=Twf1 PE=1 SV=2 0 50.518 32 10 37 10 350 40.1 6.67 24315.88086 102981.584 84821.25073 2 4 5 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;cytoskeleton;cytosol catalytic activity;nucleotide binding;protein binding Pf00241 19230 ENSMUSG00000022451.12 Twf1 15 0 High Q69Z38 Inactive tyrosine-protein kinase PEAK1 OS=Mus musculus OX=10090 GN=Peak1 PE=1 SV=4 0 66.01 19 23 37 23 1735 191 6.87 1 1 449189.4102 2017603.646 320943.5176 544854.7554 7 14 6 13 cell organization and biogenesis;cellular component movement;metabolic process cytoplasm;cytoskeleton catalytic activity;nucleotide binding Pf00069 244895 ENSMUSG00000074305.9 C230081A13Rik; Peak1 9 0 High F6S4K9 Protein 4.1 (Fragment) OS=Mus musculus OX=10090 GN=Epb41 PE=1 SV=1 0 45.813 45 13 37 2 375 40.3 4.64 cell organization and biogenesis;regulation of biological process cytoskeleton;membrane protein binding;structural molecule activity "Pf04382, Pf05902" ENSMUSG00000028906.16 4 0 High Q9DBN5 "Lon protease homolog 2, peroxisomal OS=Mus musculus OX=10090 GN=Lonp2 PE=1 SV=1" 0 64.598 28 18 37 18 852 94.5 7.23 118429.9255 13239197.88 1941226.75 2731760.525 5 6 1 8 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;membrane;nucleus;organelle lumen catalytic activity;nucleotide binding;protein binding "Pf00004, Pf01202, Pf02190, Pf04124, Pf05362, Pf07726, Pf07728, Pf13191, Pf13541" 66887 ENSMUSG00000047866.18 Lonp2 8 0 High F6RND9 Myosin phosphatase Rho-interacting protein (Fragment) OS=Mus musculus OX=10090 GN=Mprip PE=1 SV=1 0 61.099 30 20 36 20 1010 114 6.51 77535.15991 124516.0547 54032.85645 3 1 3 regulation of biological process cytoplasm;cytoskeleton;cytosol protein binding Pf00169 26936 ENSMUSG00000005417.17 Mprip 11 0 High Q9QWK4 CD5 antigen-like OS=Mus musculus OX=10090 GN=Cd5l PE=1 SV=3 0 37.861 38 11 36 11 352 38.8 5.16 4 1 1 6 2 1 1830053.682 1532637.01 235486.1484 318994.373 11 7 4 7 cell death;defense response;response to stimulus;transport cytoplasm;extracellular;membrane receptor activity "Pf00530, Pf15494" 11801 ENSMUSG00000015854.7 Cd5l 3 0 High A0A0B4J1N0 Immunoglobulin heavy variable 1-76 OS=Mus musculus OX=10090 GN=Ighv1-76 PE=1 SV=1 0 32.424 45 4 36 4 98 10.9 9.23 3 2 11 5 10796144.41 7779892.078 166066.9141 1612434.871 4 4 2 4 "Pf00047, Pf07686" 16061 ENSMUSG00000093896.2 Igh-VJ558 12 0 High P50247 Adenosylhomocysteinase OS=Mus musculus OX=10090 GN=Ahcy PE=1 SV=3 0 50.101 34 10 36 10 432 47.7 6.54 72857.19336 203663.5781 140228.2031 2 1 1 defense response;metabolic process;response to stimulus;transport cytoplasm;cytosol;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00670, Pf02254, Pf02826, Pf05221" 269378; 11615 ENSMUSG00000048087.5; ENSMUSG00000027597.15 Ahcy; Gm4737 2; 16 Sulfur amino acid metabolism; Methylation Metabolic pathways; Cysteine and methionine metabolism 0 High Q5SUA5 Unconventional myosin-Ig OS=Mus musculus OX=10090 GN=Myo1g PE=1 SV=1 0 54.665 19 15 36 14 1024 117.2 8.59 71342.32336 248984.9592 37259.83691 111048.8281 6 5 2 4 cellular component movement;regulation of biological process;response to stimulus;transport membrane catalytic activity;motor activity;nucleotide binding;protein binding "Pf00063, Pf06017" 246177 ENSMUSG00000020437.12 Myo1g 11 0 High Q9CXW4 60S ribosomal protein L11 OS=Mus musculus OX=10090 GN=Rpl11 PE=1 SV=4 0 16.598 28 4 36 4 178 20.2 9.6 1 1 1 1 249301.4824 214675.7656 113097.8594 2 1 2 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity "Pf00281, Pf00673" 67025 ENSMUSG00000059291.15 Rpl11 4 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High A0A075B5V2 Immunoglobulin heavy variable 1-34 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-34 PE=4 SV=1 0 16.425 44 4 36 1 117 13 8.73 1 2 3 2 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000093955.2 LOC673768 12 0 High E9Q9C7 Actin-binding LIM protein 1 OS=Mus musculus OX=10090 GN=Ablim1 PE=1 SV=1 0 52.667 26 13 35 13 668 75.2 8.09 69469.01758 659252.25 8409.498047 2 1 2 cell organization and biogenesis;cellular component movement;regulation of biological process cytoplasm;cytoskeleton metal ion binding;protein binding "Pf00412, Pf02209" 226251 ENSMUSG00000025085.16 Ablim1 19 0 High Q9DD20 Methyltransferase-like protein 7B OS=Mus musculus OX=10090 GN=Mettl7b PE=1 SV=2 0 32.595 38 9 35 9 244 28 8.59 3917.071167 20463.30664 26375.76172 6821.462402 2 1 1 1 metabolic process catalytic activity "Pf01209, Pf01739, Pf03848, Pf05148, Pf08241, Pf08242, Pf12847, Pf13489, Pf13578, Pf13649, Pf13659, Pf13847" 71664 ENSMUSG00000025347.4 Mettl7b 10 0 High Q8R084 UDP-glucuronosyltransferase OS=Mus musculus OX=10090 GN=Ugt2b1 PE=1 SV=1 0 49.453 32 12 35 10 529 60.1 8.37 587777.8125 945847.2656 505298.3125 812488.7839 1 2 1 2 metabolic process;response to stimulus membrane catalytic activity "Pf00201, Pf04101" 71773 ENSMUSG00000035836.2 Ugt2b1 5 Steroid hormone biosynthesis; Drug metabolism - cytochrome P450; Retinol metabolism; Metabolic pathways; Drug metabolism - other enzymes; Ascorbate and aldarate metabolism; Chemical carcinogenesis; Porphyrin and chlorophyll metabolism; Pentose and glucuronate interconversions; Metabolism of xenobiotics by cytochrome P450 0 High Q921R2 40S ribosomal protein S13 OS=Mus musculus OX=10090 GN=Rps13 PE=1 SV=1 0 18.19 28 5 35 5 140 16.1 10.71 177125.8394 191576.0859 87774.87305 177602.6191 5 4 2 4 metabolic process;regulation of biological process membrane;nucleus;ribosome RNA binding;structural molecule activity "Pf00312, Pf08069" 68052 ENSMUSG00000090862.3 Rps13 7 0 High Q91WS4 S-methylmethionine--homocysteine S-methyltransferase BHMT2 OS=Mus musculus OX=10090 GN=Bhmt2 PE=1 SV=2 0 26.827 14 4 35 1 363 39.8 6.54 metabolic process cytoplasm catalytic activity;metal ion binding Pf02574 64918 ENSMUSG00000042118.7 Bhmt2 13 Sulfur amino acid metabolism Metabolic pathways; Cysteine and methionine metabolism 0 High A0A0A6YXN4 Immunoglobulin heavy variable V1-18 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-18 PE=1 SV=1 0 32.178 56 5 35 3 117 12.9 7.94 2 3 3 4 3542283.266 1560475.539 86641.60156 320682.3945 4 4 1 3 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000076695.7 12 1 High A8Y5N4 17-beta-hydroxysteroid dehydrogenase 13 OS=Mus musculus OX=10090 GN=Hsd17b13 PE=1 SV=1 0 61.835 34 8 34 1 264 29.4 9.58 metabolic process;regulation of biological process extracellular;membrane catalytic activity "Pf00106, Pf13460" 243168 ENSMUSG00000034528.15 Hsd17b13 5 0 High P32020 Non-specific lipid-transfer protein OS=Mus musculus OX=10090 GN=Scp2 PE=1 SV=3 0 65.915 43 17 34 17 547 59.1 7.44 233280.5576 109861.7881 163545.0039 12636.22095 4 4 2 3 cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;cytosol;endoplasmic reticulum;membrane;mitochondrion;nucleus;organelle lumen catalytic activity;protein binding;transporter activity "Pf00108, Pf00109, Pf02036, Pf02801, Pf02803, Pf08545, Pf14864" 20280 ENSMUSG00000028603.15 Scp2 4 Beta-oxidation of pristanoyl-CoA; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; alpha-linolenic acid (ALA) metabolism PPAR signaling pathway; Metabolic pathways; Primary bile acid biosynthesis; Peroxisome 0 High Q62452 UDP-glucuronosyltransferase 1-9 OS=Mus musculus OX=10090 GN=Ugt1a9 PE=1 SV=3 0 56.856 39 13 34 5 528 60 8.35 34598.84009 56399.09131 9430.4375 2 2 1 metabolic process;regulation of biological process endoplasmic reticulum;membrane catalytic activity;enzyme regulator activity;protein binding "Pf00201, Pf04101" 394434 ENSMUSG00000090175.1 Ugt1a9 1 Glucuronidation Steroid hormone biosynthesis; Drug metabolism - cytochrome P450; Retinol metabolism; Metabolic pathways; Drug metabolism - other enzymes; Ascorbate and aldarate metabolism; Chemical carcinogenesis; Porphyrin and chlorophyll metabolism; Pentose and glucuronate interconversions; Metabolism of xenobiotics by cytochrome P450 0 High D3YUW7 Cingulin OS=Mus musculus OX=10090 GN=Cgn PE=1 SV=2 0 64.087 22 19 34 19 1183 135.5 5.86 143470.4453 96078.04688 172624.4453 78089.46997 6 1 2 5 0 High E9Q6R7 Utrophin OS=Mus musculus OX=10090 GN=Utrn PE=1 SV=1 0 68.67 8 21 34 21 3430 392.5 5.33 1039093.36 1285208.807 204152.7168 397062.1316 14 8 2 8 cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane metal ion binding;protein binding "Pf00307, Pf00397, Pf00435, Pf00569, Pf09068, Pf09069, Pf11971" 22288 ENSMUSG00000019820.10 Utrn 10 0 High A0A0G2JG10 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Mus musculus OX=10090 GN=Dhx15 PE=1 SV=1 0 26.582 19 10 34 10 608 68.5 6.8 1 1 62051.40515 1193877.806 42608.31641 756111.6653 4 8 3 5 catalytic activity;nucleotide binding "Pf00270, Pf00271, Pf04408, Pf13401" ENSMUSG00000029169.11 5 0 High P08752 Guanine nucleotide-binding protein G(i) subunit alpha-2 OS=Mus musculus OX=10090 GN=Gnai2 PE=1 SV=5 0 51.552 47 14 34 10 355 40.5 5.45 303417.2693 9655.457031 49216.7627 71756.52979 4 1 2 3 cell division;cell proliferation;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding;signal transducer activity "Pf00025, Pf00503" 14678 ENSMUSG00000032562.13 Gnai2 9 "Adenylate cyclase inhibitory pathway; G-protein activation; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Adrenaline,noradrenaline inhibits insulin secretion; PLC beta mediated events; ADP signalling through P2Y purinoceptor 12" Oxytocin signaling pathway; Leukocyte transendothelial migration; Morphine addiction; Cholinergic synapse; Chagas disease (American trypanosomiasis); Retrograde endocannabinoid signaling; Dopaminergic synapse; Progesterone-mediated oocyte maturation; GABAergic synapse; Regulation of lipolysis in adipocytes; Toxoplasmosis; Chemokine signaling pathway; Platelet activation; Melanogenesis; Axon guidance; Sphingolipid signaling pathway; Glutamatergic synapse; Pertussis; Parkinson's disease; Cocaine addiction; Long-term depression; cGMP-PKG signaling pathway; Rap1 signaling pathway; Pathways in cancer; Alcoholism; cAMP signaling pathway; Tight junction; Gastric acid secretion; Renin secretion; Gap junction; Circadian entrainment; Estrogen signaling pathway; Serotonergic synapse; Adrenergic signaling in cardiomyocytes 4 High P67984 60S ribosomal protein L22 OS=Mus musculus OX=10090 GN=Rpl22 PE=1 SV=2 0 20.253 45 5 34 5 128 14.8 9.19 1 1 61020.11328 12879412.55 1306067.801 62394.8269 2 3 2 2 cell differentiation;metabolic process cytoplasm;nucleus;ribosome RNA binding;structural molecule activity Pf01776 19934; 100047372; 102642602 ENSMUSG00000028936.15 Rpl22; LOC100047372; LOC100504863; LOC102642602 4; 7 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High P10649 Glutathione S-transferase Mu 1 OS=Mus musculus OX=10090 GN=Gstm1 PE=1 SV=2 0 34.525 46 10 34 10 218 26 7.94 22762.38818 89963.58203 242979.5938 3 5 2 metabolic process;response to stimulus cytoplasm;cytosol;extracellular catalytic activity;metal ion binding;protein binding "Pf00043, Pf02798, Pf13417, Pf14497" 14862 ENSMUSG00000058135.12 Gstm1 3 Glutathione metabolism; Platinum drug resistance; Drug metabolism - cytochrome P450; Chemical carcinogenesis; Metabolism of xenobiotics by cytochrome P450 0 High P60843 Eukaryotic initiation factor 4A-I OS=Mus musculus OX=10090 GN=Eif4a1 PE=1 SV=1 0 35.149 22 7 33 4 406 46.1 5.48 835079.418 217242.8857 80245.33008 717240.5073 6 3 1 3 metabolic process;regulation of biological process cytoplasm;membrane catalytic activity;DNA binding;nucleotide binding;protein binding;RNA binding "Pf00270, Pf00271, Pf04851" 13681 ENSMUSG00000059796.16 Eif4a1 11 L13a-mediated translational silencing of Ceruloplasmin expression; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ISG15 antiviral mechanism; Translation initiation complex formation; Deadenylation of mRNA RNA transport 3 High Q9WVL0 Maleylacetoacetate isomerase OS=Mus musculus OX=10090 GN=Gstz1 PE=1 SV=1 0 45.563 68 10 33 10 216 24.3 7.85 129988.2664 258968.7358 116267.4395 492068.1846 4 4 3 6 metabolic process cytoplasm;mitochondrion catalytic activity;protein binding "Pf00043, Pf02798, Pf13409, Pf13417" 14874 ENSMUSG00000021033.10 Gstz1 12 Phenylalanine and tyrosine catabolism; Glutathione conjugation Metabolic pathways; Tyrosine metabolism 0 High P28798 Progranulin OS=Mus musculus OX=10090 GN=Grn PE=1 SV=2 0 53.428 25 9 33 9 589 63.4 6.8 28851.26855 2 cell proliferation;regulation of biological process;response to stimulus;transport endoplasmic reticulum;endosome;extracellular;mitochondrion;vacuole protein binding;RNA binding Pf00396 14824 Grn 11 0 High P62911 60S ribosomal protein L32 OS=Mus musculus OX=10090 GN=Rpl32 PE=1 SV=2 0 27.207 38 6 33 6 135 15.9 11.33 1 1 613056.8057 541970.915 265635.1755 5 5 3 Met-loss [N-Term] metabolic process;response to stimulus membrane;ribosome RNA binding;structural molecule activity Pf01655 19951; 652989 ENSMUSG00000057841.5 Rpl32; Rpl32p 6; X L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High P50427 Steryl-sulfatase OS=Mus musculus OX=10090 GN=Sts PE=1 SV=1 0 89.607 31 16 33 16 624 66.5 8.5 131163.9688 58413.58398 63761.86023 1 2 4 metabolic process endoplasmic reticulum;membrane catalytic activity;metal ion binding "Pf00884, Pf01663, Pf14707" 20905 Sts X|Y Steroid hormone biosynthesis 0 High O35945 "Aldehyde dehydrogenase, cytosolic 1 OS=Mus musculus OX=10090 GN=Aldh1a7 PE=1 SV=1" 0 45.638 28 10 33 3 501 54.6 7.71 Met-loss+Acetyl [N-Term] metabolic process cytoplasm catalytic activity "Pf00171, Pf05893, Pf07368" 26358 ENSMUSG00000024747.3 Aldh1a7 19 RA biosynthesis pathway; Ethanol oxidation; Fructose catabolism Retinol metabolism; Metabolic pathways 0 High G3UXT7 RNA-binding protein FUS (Fragment) OS=Mus musculus OX=10090 GN=Fus PE=1 SV=1 0 33.913 61 8 33 7 130 14 8.97 1 1 280359.2661 7948.143066 10551.60645 5 1 1 regulation of biological process cytoplasm;nucleus metal ion binding;RNA binding "Pf00076, Pf00641, Pf13893, Pf14259" ENSMUSG00000030795.18 7 1 High Q9JM76 Actin-related protein 2/3 complex subunit 3 OS=Mus musculus OX=10090 GN=Arpc3 PE=1 SV=3 0 31.774 43 8 33 8 178 20.5 8.59 79419.01465 33753.9375 8113.264648 2 2 1 Met-loss [N-Term] cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane protein binding;structural molecule activity Pf04062 56378 ENSMUSG00000029465.14 Arpc3 5 RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling; Regulation of actin dynamics for phagocytic cup formation Endocytosis; Regulation of actin cytoskeleton; Salmonella infection; Fc gamma R-mediated phagocytosis; Bacterial invasion of epithelial cells 0 High Q3THW5 Histone H2A.V OS=Mus musculus OX=10090 GN=H2az2 PE=1 SV=3 0 7.903 23 3 33 1 128 13.5 10.58 1 1 1 2 68888.69531 1 regulation of biological process chromosome;nucleus DNA binding;protein binding Pf00125 77605 ENSMUSG00000041126.16 H2afv 11 Meiotic Recombination; Mus musculus biological processes; NoRC negatively regulates rRNA expression; Meiotic Synapsis Alcoholism; Systemic lupus erythematosus 0 High Q02257 Junction plakoglobin OS=Mus musculus OX=10090 GN=Jup PE=1 SV=3 0 40.561 25 14 32 13 745 81.7 6.14 612492.6748 978485.7188 44413.03516 175452.7744 7 9 2 5 Acetyl [N-Term] cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;nucleus protein binding;signal transducer activity;structural molecule activity Pf00514 16480 ENSMUSG00000001552.14 Jup 11 Formation of the cornified envelope; VEGFR2 mediated vascular permeability; Neutrophil degranulation; Adherens junctions interactions Acute myeloid leukemia; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Transcriptional misregulation in cancer; Pathways in cancer 1 High Q9D8N0 Elongation factor 1-gamma OS=Mus musculus OX=10090 GN=Eef1g PE=1 SV=3 0 25.144 16 5 32 5 437 50 6.74 104661.5991 32906.07813 76979.56152 3 2 3 metabolic process;response to stimulus cytoplasm;endoplasmic reticulum;membrane;nucleus catalytic activity;protein binding;RNA binding "Pf00043, Pf00647, Pf02798, Pf13409, Pf13410, Pf13417, Pf14497" 67160 ENSMUSG00000071644.10 Eef1g 19 Eukaryotic Translation Elongation Legionellosis 0 High P42932 T-complex protein 1 subunit theta OS=Mus musculus OX=10090 GN=Cct8 PE=1 SV=3 0 30.12 22 10 32 10 548 59.5 5.62 107345.1392 4768.493652 9345.292969 29354.37891 7 1 1 3 cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;cytosol nucleotide binding;protein binding Pf00118 12469 ENSMUSG00000025613.13 Cct8 16 Neutrophil degranulation; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Association of TriC/CCT with target proteins during biosynthesis 0 High Q8VCR2 17-beta-hydroxysteroid dehydrogenase 13 OS=Mus musculus OX=10090 GN=Hsd17b13 PE=1 SV=2 0 59.662 35 10 32 3 304 33.4 8.88 14841.56445 104616.3203 94589.60938 2559.610596 1 1 1 1 metabolic process;regulation of biological process extracellular catalytic activity "Pf00106, Pf08659" 243168 ENSMUSG00000034528.15 Hsd17b13 5 Lipid particle organization 8 High P08607 C4b-binding protein OS=Mus musculus OX=10090 GN=C4bpa PE=1 SV=3 0 44.191 28 11 32 11 469 51.5 7.15 85552.84106 67749.75195 8044.749512 35269.7688 5 2 1 3 defense response;metabolic process;regulation of biological process;response to stimulus extracellular protein binding;RNA binding Pf00084 12269 ENSMUSG00000026405.14 C4bp 1 Complement and coagulation cascades; Pertussis 0 High P63037 DnaJ homolog subfamily A member 1 OS=Mus musculus OX=10090 GN=Dnaja1 PE=1 SV=1 0 40.326 31 9 32 9 397 44.8 7.08 76399.73828 92880.87451 84459.04883 16918.55469 2 4 2 1 cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;endoplasmic reticulum;membrane;mitochondrion;nucleus enzyme regulator activity;metal ion binding;nucleotide binding;protein binding "Pf00226, Pf00684, Pf01556" 15502 ENSMUSG00000028410.13 Dnaja1 4 HSP90 chaperone cycle for steroid hormone receptors (SHR) Protein processing in endoplasmic reticulum 0 High P84099 60S ribosomal protein L19 OS=Mus musculus OX=10090 GN=Rpl19 PE=1 SV=1 0 27.941 31 7 32 7 196 23.5 11.47 190331.3184 200205.9365 67452.24463 4 3 2 metabolic process membrane;ribosome RNA binding;structural molecule activity Pf01280 19921; 100041511 ENSMUSG00000017404.12 Rpl19; Rpl19-ps11 11; 8 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q6ZWZ4 60S ribosomal protein L36 OS=Mus musculus OX=10090 GN=Rpl36 PE=1 SV=1 0 16.34 30 5 31 5 105 12.2 11.59 103589.4229 310701.3711 18025.86133 69278.95313 3 3 1 3 metabolic process ribosome RNA binding;structural molecule activity Pf01158 54217 ENSMUSG00000057863.5 Rpl36 17 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High P13707 "Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic OS=Mus musculus OX=10090 GN=Gpd1 PE=1 SV=3" 0 31.925 37 9 31 9 349 37.5 7.17 5 2 1 7 3 1 2503164.238 1420856.385 1122797.992 604780.6299 9 7 8 8 metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;mitochondrion catalytic activity;nucleotide binding;protein binding "Pf01210, Pf07479" 14555 ENSMUSG00000023019.12 Gpd1 15 Synthesis of PA Glycerophospholipid metabolism 0 High Q9CW42 Mitochondrial amidoxime-reducing component 1 OS=Mus musculus OX=10090 GN=Mtarc1 PE=1 SV=2 0 52.957 51 12 31 11 340 38 8.59 1659463.535 17707.29492 2029094.875 2 1 1 metabolic process membrane;mitochondrion catalytic activity;metal ion binding "Pf03473, Pf03476" 66112 ENSMUSG00000026621.13 Marc1; Mosc1 1 Phase I - Functionalization of compounds 1 High Q7TT50 Serine/threonine-protein kinase MRCK beta OS=Mus musculus OX=10090 GN=Cdc42bpb PE=1 SV=2 0 49.021 14 15 31 15 1713 194.6 6.46 140268.141 195006.657 46704.64893 224086.5195 6 6 2 5 cell differentiation;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;Golgi;membrane catalytic activity;metal ion binding;motor activity;nucleotide binding;protein binding "Pf00069, Pf00130, Pf00261, Pf00433, Pf00769, Pf00780, Pf00786, Pf01576, Pf02463, Pf03148, Pf03962, Pf04111, Pf04156, Pf04849, Pf05276, Pf05483, Pf05557, Pf05622, Pf05667, Pf05701, Pf06008, Pf06160, Pf07111, Pf07321, Pf07714, Pf07888, Pf07926, Pf08317, Pf08826, Pf09726, Pf09728, Pf09730, Pf09731, Pf09787, Pf10174, Pf10473, Pf10498, Pf12072, Pf12128, Pf12718, Pf12795, Pf13514, Pf13851, Pf13868, Pf13870, Pf14817, Pf14988, Pf14992, Pf15035, Pf15294, Pf15558, Pf15619" 217866 ENSMUSG00000021279.4 Cdc42bpb 12 0 High Q6PD26 GPI transamidase component PIG-S OS=Mus musculus OX=10090 GN=Pigs PE=1 SV=3 0 48.538 33 12 31 12 555 61.7 6.93 56569.39014 64413.18359 54820.49512 3 4 5 Met-loss [N-Term]; Met-loss+Acetyl [N-Term] metabolic process endoplasmic reticulum;membrane catalytic activity Pf10510 276846 ENSMUSG00000041958.10 Pigs 11 Attachment of GPI anchor to uPAR Glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Metabolic pathways 0 High G3X8X6 Sialoadhesin OS=Mus musculus OX=10090 GN=Siglec1 PE=1 SV=1 0 64.366 13 15 31 15 1701 183.5 6.68 93801.2251 112229.3945 31709.50098 41282.13379 4 3 2 2 regulation of biological process;transport extracellular;membrane protein binding "Pf00047, Pf07679, Pf07686, Pf08205, Pf13895, Pf13927" 20612 ENSMUSG00000027322.11 Siglec1 2 Cell adhesion molecules (CAMs) 0 High Q9JI91 Alpha-actinin-2 OS=Mus musculus OX=10090 GN=Actn2 PE=1 SV=2 0 48.998 14 12 30 1 894 103.8 5.45 cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane metal ion binding;protein binding "Pf00307, Pf00435, Pf08726, Pf11971, Pf13499, Pf13833" 11472 ENSMUSG00000052374.14 Actn2 13 "RAF/MAP kinase cascade; CREB phosphorylation through the activation of CaMKII; Ras activation uopn Ca2+ infux through NMDA receptor; Platelet degranulation ; Striated Muscle Contraction; Unblocking of NMDA receptor, glutamate binding and activation; Interleukin-20 family signaling" Leukocyte transendothelial migration; Regulation of actin cytoskeleton; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Focal adhesion; Adherens junction; Tight junction; Systemic lupus erythematosus; Amoebiasis; Viral carcinogenesis 0 High P62960 Y-box-binding protein 1 OS=Mus musculus OX=10090 GN=Ybx1 PE=1 SV=3 0 47.763 52 7 30 7 322 35.7 9.88 99468.21094 155811.4648 25693.47656 7368.825195 3 3 2 1 Met-loss+Acetyl [N-Term] metabolic process;regulation of biological process cytoplasm;cytosol;extracellular;membrane;nucleus;spliceosomal complex DNA binding;protein binding;RNA binding Pf00313 22608 ENSMUSG00000028639.14 Ybx1 4 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway 0 High Q99KY4 Cyclin-G-associated kinase OS=Mus musculus OX=10090 GN=Gak PE=1 SV=2 0 44.854 17 16 30 16 1305 143.6 5.73 44454.57666 95693.20801 103228.6465 13635.33789 2 3 3 3 Met-loss+Acetyl [N-Term] cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;cytosol;Golgi;membrane catalytic activity;nucleotide binding;protein binding "Pf00069, Pf00226, Pf07714, Pf10409" 231580 Gak 5 0 High D3Z383 Mesoderm-specific transcript protein OS=Mus musculus OX=10090 GN=Mest PE=4 SV=2 0 36.312 36 10 30 10 342 39.5 9.5 77703.51465 57132.06934 221024.3013 2 2 4 regulation of biological process;response to stimulus endoplasmic reticulum;membrane catalytic activity "Pf00561, Pf06342, Pf12695, Pf12697" 17294 ENSMUSG00000051855.15 Mest 6 0 High P38060 "Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Mus musculus OX=10090 GN=Hmgcl PE=1 SV=2" 0 35.226 31 8 30 8 325 34.2 8.41 120130.0015 186696.9272 85056.75195 54843.78223 4 4 3 4 cell organization and biogenesis;metabolic process;response to stimulus membrane;mitochondrion;organelle lumen catalytic activity;metal ion binding;protein binding Pf00682 15356 ENSMUSG00000028672.13 Hmgcl 4 Synthesis of Ketone Bodies "Valine, leucine and isoleucine degradation; Metabolic pathways; Butanoate metabolism; Synthesis and degradation of ketone bodies; Peroxisome" 0 High Q0VGU4 Neurosecretory protein VGF OS=Mus musculus OX=10090 GN=Vgf PE=1 SV=1 0 44.224 25 10 30 10 617 68.2 4.7 319296.3125 1108477.801 39700.10156 17673.87305 2 3 1 1 metabolic process;regulation of biological process;reproduction;response to stimulus;transport extracellular;membrane protein binding 381677 ENSMUSG00000037428.14 Vgf 5 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation 0 High P45591 Cofilin-2 OS=Mus musculus OX=10090 GN=Cfl2 PE=1 SV=1 0 28.725 58 8 29 5 166 18.7 7.88 23897.60352 97283.14844 48022.42969 1 1 1 Met-loss+Acetyl [N-Term] cell organization and biogenesis;cellular homeostasis;regulation of biological process cytoplasm;cytoskeleton;nucleus protein binding Pf00241 12632 ENSMUSG00000062929.7 Cfl2 12 Regulation of actin cytoskeleton; Axon guidance; Pertussis; Fc gamma R-mediated phagocytosis 0 High Q8C6G1 Cilia- and flagella-associated protein 410 OS=Mus musculus OX=10090 GN=Cfap410 PE=1 SV=1 0 45.429 53 10 29 10 249 28.2 6.93 151183.0078 649601.5894 174972.916 357768.5254 5 4 3 4 cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane;mitochondrion protein binding "Pf12799, Pf13855, Pf14580" 67884 ENSMUSG00000020284.16 1810043G02Rik 10 0 High Q9D898 Actin-related protein 2/3 complex subunit 5-like protein OS=Mus musculus OX=10090 GN=Arpc5l PE=1 SV=1 0 29.453 58 5 29 5 153 17 6.8 9134.121094 1 cell organization and biogenesis;cellular component movement;regulation of biological process cytoplasm;cytoskeleton protein binding Pf04699 74192 ENSMUSG00000026755.14 Arpc5l 2 Endocytosis; Regulation of actin cytoskeleton; Salmonella infection; Fc gamma R-mediated phagocytosis; Bacterial invasion of epithelial cells 0 High Q8VDC1 FYVE and coiled-coil domain-containing protein 1 OS=Mus musculus OX=10090 GN=Fyco1 PE=1 SV=1 0 66.819 20 22 29 22 1437 162.2 4.98 119979.3984 175285.4922 25417.14258 372637.4263 7 2 1 3 cellular component movement;metabolic process;regulation of biological process;transport endosome;Golgi;membrane;vacuole catalytic activity;metal ion binding;motor activity;nucleotide binding;protein binding "Pf01363, Pf01576, Pf02759, Pf10174, Pf12128, Pf13897" 17281 ENSMUSG00000025241.16 Fyco1 9 0 High Q8BVW3 Tripartite motif-containing protein 14 OS=Mus musculus OX=10090 GN=Trim14 PE=1 SV=2 0 47.548 40 12 29 12 440 49.6 7.93 222513.6641 165417.1055 135977.001 60808.48096 5 4 3 3 defense response;regulation of biological process;response to stimulus cytoplasm metal ion binding;protein binding "Pf00622, Pf00643, Pf13534, Pf13765" 74735 ENSMUSG00000039853.18 Trim14 4 0 High Q8VCB3 "Glycogen [starch] synthase, liver OS=Mus musculus OX=10090 GN=Gys2 PE=1 SV=2" 0 37.582 21 11 29 10 704 80.8 6.89 1 1 200799.5117 208921.3047 63997.16797 35773.3877 4 3 1 4 metabolic process;response to stimulus cytoplasm;cytoskeleton;cytosol catalytic activity "Pf00534, Pf05693" 232493 ENSMUSG00000030244.7 Gys2 6 Glycogen synthesis Insulin signaling pathway; Metabolic pathways; Insulin resistance; Starch and sucrose metabolism; PI3K-Akt signaling pathway; AMPK signaling pathway; Glucagon signaling pathway 1 High A0A087WS16 "Collagen, type VI, alpha 3 OS=Mus musculus OX=10090 GN=Col6a3 PE=1 SV=1" 0 32.876 7 13 29 13 2677 288.5 8.53 7 2 1 7 2 1 1528281.893 744676.2236 471364.5139 191344.48 11 11 5 7 regulation of biological process extracellular;membrane enzyme regulator activity;protein binding "Pf00014, Pf00041, Pf00092, Pf01391, Pf13519, Pf13768" ENSMUSG00000048126.16 1 ECM proteoglycans; Collagen chain trimerization; Integrin cell surface interactions; NCAM1 interactions; Collagen degradation; Signaling by PDGF; Assembly of collagen fibrils and other multimeric structures 0 High P70333 Heterogeneous nuclear ribonucleoprotein H2 OS=Mus musculus OX=10090 GN=Hnrnph2 PE=1 SV=1 0 36.819 26 8 28 3 449 49.2 6.3 1 1 86866.54688 33541.84766 66309.58594 38419.91016 1 1 1 1 cytosol;membrane;nucleus RNA binding "Pf00076, Pf08080, Pf14259" 56258 ENSMUSG00000045427.13 Hnrnph2 X mRNA Splicing - Major Pathway 0 High Q61990 Poly(rC)-binding protein 2 OS=Mus musculus OX=10090 GN=Pcbp2 PE=1 SV=1 0 23.009 30 6 28 3 362 38.2 6.79 55480.125 45233.92969 22517.34668 118969.1504 1 1 2 3 defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;nucleus DNA binding;protein binding;RNA binding "Pf00013, Pf13014" 18521 ENSMUSG00000056851.13 Pcbp2 15 mRNA Splicing - Major Pathway 1 High P62751 60S ribosomal protein L23a OS=Mus musculus OX=10090 GN=Rpl23a PE=1 SV=1 0 18.437 35 6 28 6 156 17.7 10.45 53355.23633 113235.3359 9349.466797 33090.5918 3 2 1 2 cell organization and biogenesis;metabolic process nucleus;ribosome protein binding;RNA binding;structural molecule activity "Pf00276, Pf03939" 268449 ENSMUSG00000058546.8 Rpl23a 11 Ribosome 0 High O55143 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 OS=Mus musculus OX=10090 GN=Atp2a2 PE=1 SV=2 0 38.929 17 15 28 15 1044 114.8 5.34 222288.9897 86045.44678 143072.7627 9 4 7 cell organization and biogenesis;cellular homeostasis;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;membrane catalytic activity;metal ion binding;nucleotide binding;protein binding;transporter activity "Pf00122, Pf00689, Pf00690, Pf00702, Pf08282, Pf12710, Pf13246" 11938 ENSMUSG00000029467.15 Atp2a2 5 Ion transport by P-type ATPases; Ion homeostasis; Reduction of cytosolic Ca++ levels Hypertrophic cardiomyopathy (HCM); Pancreatic secretion; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Dilated cardiomyopathy; Thyroid hormone signaling pathway; cGMP-PKG signaling pathway; Calcium signaling pathway; Alzheimer's disease; Cardiac muscle contraction; cAMP signaling pathway; Adrenergic signaling in cardiomyocytes 0 High O70475 UDP-glucose 6-dehydrogenase OS=Mus musculus OX=10090 GN=Ugdh PE=1 SV=1 0 53.481 39 13 28 13 493 54.8 7.56 34158.875 639634.6875 1 2 metabolic process cytosol;nucleus catalytic activity;nucleotide binding "Pf00984, Pf03720, Pf03721" 22235 ENSMUSG00000029201.14 Ugdh 5 "Formation of the active cofactor, UDP-glucuronate" Metabolic pathways; Amino sugar and nucleotide sugar metabolism; Ascorbate and aldarate metabolism; Pentose and glucuronate interconversions 0 High Q922I7 Polypyrimidine tract-binding protein 1 OS=Mus musculus OX=10090 GN=Ptbp1 PE=1 SV=1 0 27.279 27 9 28 9 555 59.3 9.16 1 1 124067.2832 345817.4805 133123.9521 153908.136 4 5 4 6 Acetyl [N-Term] metabolic process;regulation of biological process cytoplasm;membrane;nucleus catalytic activity;DNA binding;protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 19205 ENSMUSG00000006498.16 Ptbp1 10 mRNA Splicing - Major Pathway; FGFR2 alternative splicing 0 High Q9JJI8 60S ribosomal protein L38 OS=Mus musculus OX=10090 GN=Rpl38 PE=1 SV=3 0 21.278 50 4 28 4 70 8.2 10.1 42197.6416 49144.5625 45416.63281 2 1 2 cell organization and biogenesis;metabolic process;regulation of biological process ribosome RNA binding;structural molecule activity Pf01781 67671; 625646; 664868 ENSMUSG00000057322.12 Rpl38; Rpl38-ps1; Rpl38-ps2 11; 4; 6 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q3U0I3 T-complex protein 1 subunit gamma OS=Mus musculus OX=10090 GN=Cct3 PE=1 SV=1 0 25.776 24 9 28 9 521 58.2 7.25 143598.5723 42647.69922 88415.46875 49179.19824 7 2 2 4 Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;cytosol;membrane nucleotide binding;protein binding;RNA binding Pf00118 12462 ENSMUSG00000001416.13 Cct3 3 0 High Q60902 Epidermal growth factor receptor substrate 15-like 1 OS=Mus musculus OX=10090 GN=Eps15l1 PE=1 SV=3 0 47.367 18 13 27 13 907 99.2 5.02 245452.2043 816212.7676 53323.88281 155499.8633 5 3 1 2 cell differentiation;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;Golgi;membrane;nucleus catalytic activity;metal ion binding;motor activity;nucleotide binding;protein binding;structural molecule activity;transporter activity "Pf00038, Pf00261, Pf00529, Pf00769, Pf01496, Pf01576, Pf02321, Pf02463, Pf02841, Pf02994, Pf03148, Pf03938, Pf03962, Pf03999, Pf04012, Pf04111, Pf04156, Pf04778, Pf04912, Pf05103, Pf05149, Pf05478, Pf05483, Pf05557, Pf05622, Pf05667, Pf05701, Pf06008, Pf06160, Pf06818, Pf07111, Pf07798, Pf07888, Pf07926, Pf08317, Pf08614, Pf09311, Pf09726, Pf09730, Pf09731, Pf09755, Pf10146, Pf10168, Pf10174, Pf10186, Pf10234, Pf10359, Pf10498, Pf11180, Pf11559, Pf11932, Pf12128, Pf12325, Pf12329, Pf12685, Pf12718, Pf12763, Pf12795, Pf13094, Pf13166, Pf13514, Pf13851, Pf13863, Pf13868, Pf13870, Pf13949, Pf14073, Pf14362, Pf14662, Pf14817, Pf14915, Pf14932, Pf14992, Pf15070, Pf15112, Pf15175, Pf15346, Pf15397, Pf15619" 13859 ENSMUSG00000006276.10 Eps15l1 8 Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation Endocytosis 0 High P62754 40S ribosomal protein S6 OS=Mus musculus OX=10090 GN=Rps6 PE=1 SV=1 0 19.924 31 7 26 7 249 28.7 10.84 1 1 282635.6016 192989.4534 28020.00195 117243.6211 2 2 1 2 cell death;cell differentiation;cell proliferation;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity Pf01092 667739; 20104; 105244208 ENSMUSG00000028495.14 Rps6-ps4; Rps6; LOC105244208 2; 4 mTOR signaling pathway; Ribosome; Insulin signaling pathway; Proteoglycans in cancer; HIF-1 signaling pathway; PI3K-Akt signaling pathway; EGFR tyrosine kinase inhibitor resistance 0 High Q9CQQ4 Gem-associated protein 2 OS=Mus musculus OX=10090 GN=Gemin2 PE=2 SV=1 0 13.494 36 5 26 5 269 30.4 5.53 2 3 937998.0068 78903.65869 184140.0762 5 2 5 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process cytoplasm;cytosol;nucleus;spliceosomal complex Pf04938 66603 ENSMUSG00000060121.15 Gemin2; Sip1 12 snRNP Assembly RNA transport 0 High Q8CGK3 "Lon protease homolog, mitochondrial OS=Mus musculus OX=10090 GN=Lonp1 PE=1 SV=2" 0 35.21 20 12 26 12 949 105.8 6.57 426163.7832 177002.6504 15595.39453 615592.502 5 5 1 7 cell organization and biogenesis;metabolic process;response to stimulus cytosol;membrane;mitochondrion;nucleus;organelle lumen catalytic activity;DNA binding;nucleotide binding;protein binding;RNA binding "Pf00004, Pf00910, Pf01695, Pf02190, Pf05362, Pf05496, Pf07724, Pf07726, Pf07728, Pf08298, Pf13173, Pf13191, Pf13207, Pf13401, Pf13541" 74142 ENSMUSG00000041168.9 Lonp1 17 0 High P62983 Ubiquitin-40S ribosomal protein S27a OS=Mus musculus OX=10090 GN=Rps27a PE=1 SV=2 0 13.898 32 4 26 4 156 17.9 9.64 10754.05078 6756.847168 2 1 metabolic process cytoplasm;cytosol;membrane;nucleus;ribosome metal ion binding;protein binding;RNA binding;structural molecule activity "Pf00240, Pf01599, Pf11976, Pf13019, Pf13881, Pf14560" 78294; 619900; 100042019 ENSMUSG00000020460.15 Rps27a; Rps27a-ps2; LOC100042019 11; 9 "Termination of translesion DNA synthesis; PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1; NOD1/2 Signaling Pathway; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Ovarian tumor domain proteases; UCH proteinases; Stimuli-sensing channels; p75NTR recruits signalling complexes; Josephin domain DUBs; Spry regulation of FGF signaling; SRP-dependent cotranslational protein targeting to membrane; Ub-specific processing proteases; IKK complex recruitment mediated by RIP1; IRAK2 mediated activation of TAK1 complex; Activation of NF-kappaB in B cells; EGFR downregulation; Regulation of necroptotic cell death; Regulation of signaling by CBL; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Formation of a pool of free 40S subunits; Regulation of TP53 Degradation; Regulation of TP53 Activity through Phosphorylation; NF-kB is activated and signals survival; Downstream TCR signaling; Association of licensing factors with the pre-replicative complex; Autodegradation of Cdh1 by Cdh1:APC/C; TRAF6-mediated induction of TAK1 complex within TLR4 complex; Asymmetric localization of PCP proteins; Interleukin-1 family signaling; TNFR1-induced NFkappaB signaling pathway; G2/M Checkpoints; Regulation of PTEN localization; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Mus musculus biological processes; Regulation of PTEN stability and activity; APC-Cdc20 mediated degradation of Nek2A; Formation of the ternary complex, and subsequently, the 43S complex; Regulation of TP53 Activity through Methylation; E3 ubiquitin ligases ubiquitinate target proteins; Translesion synthesis by POLI; Interleukin-20 family signaling; Downregulation of ERBB4 signaling; Dual Incision in GG-NER; ER Quality Control Compartment (ERQC); Neddylation; Negative regulators of DDX58/IFIH1 signaling; Gap-filling DNA repair synthesis and ligation in TC-NER; APC/C:Cdc20 mediated degradation of Securin; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Antigen processing: Ubiquitination & Proteasome degradation; Translesion Synthesis by POLH; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; TAK1 activates NFkB by phosphorylation and activation of IKKs complex; Oxidative Stress Induced Senescence; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Regulation of PLK1 Activity at G2/M Transition; Senescence-Associated Secretory Phenotype (SASP); Oncogene Induced Senescence; Formation of TC-NER Pre-Incision Complex; AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of expression of SLITs and ROBOs; APC/C:Cdc20 mediated degradation of Cyclin B; Translation initiation complex formation; Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon; Regulation of FZD by ubiquitination; Recognition of DNA damage by PCNA-containing replication complex; Translesion synthesis by REV1; Circadian Clock; Degradation of DVL; Degradation of AXIN; The role of GTSE1 in G2/M progression after G2 checkpoint; CDT1 association with the CDC6:ORC:origin complex; Endosomal Sorting Complex Required For Transport (ESCRT); Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Degradation of beta-catenin by the destruction complex; NRIF signals cell death from the nucleus; Autodegradation of the E3 ubiquitin ligase COP1; MAPK6/MAPK4 signaling; SCF-beta-TrCP mediated degradation of Emi1; CDK-mediated phosphorylation and removal of Cdc6; Separation of Sister Chromatids; SCF(Skp2)-mediated degradation of p27/p21; Regulation of innate immune responses to cytosolic DNA; GLI3 is processed to GLI3R by the proteasome; Translesion synthesis by POLK; Activated TLR4 signalling; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); DNA Damage Recognition in GG-NER; Degradation of GLI1 by the proteasome; FCERI mediated NF-kB activation; Formation of Incision Complex in GG-NER; Gap-filling DNA repair synthesis and ligation in GG-NER; Hedgehog ligand biogenesis; Regulation of RAS by GAPs; Activated NOTCH1 Transmits Signal to the Nucleus; Cyclin D associated events in G1; Dual incision in TC-NER; Negative regulation of MAPK pathway; Pink/Parkin Mediated Mitophagy; Cargo recognition for clathrin-mediated endocytosis; Ubiquitin-dependent degradation of Cyclin D1; Metalloprotease DUBs; MAP3K8 (TPL2)-dependent MAPK1/3 activation; NIK-->noncanonical NF-kB signaling; Removal of licensing factors from origins; IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation; M/G1 Transition; Negative regulation of MET activity; L13a-mediated translational silencing of Ceruloplasmin expression; Downregulation of ERBB2:ERBB3 signaling; activated TAK1 mediates p38 MAPK activation; Regulation of RUNX2 expression and activity; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ABC-family proteins mediated transport; Regulation of DNA replication; Glycogen synthesis; Dectin-1 mediated noncanonical NF-kB signaling; Downregulation of SMAD2/3:SMAD4 transcriptional activity; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Orc1 removal from chromatin; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition); Regulation of TNFR1 signaling; Regulation of RUNX3 expression and activity; Hedgehog 'on' state; Fanconi Anemia Pathway; HDR through Homologous Recombination (HRR); Iron uptake and transport; JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Signalling by NGF; Downregulation of TGF-beta receptor signaling" Ribosome 0 High Q8CIE6 Coatomer subunit alpha OS=Mus musculus OX=10090 GN=Copa PE=1 SV=2 0 42.777 17 16 26 16 1224 138.3 7.65 331930.3237 51338.31104 217966.2656 73066.96167 3 4 1 6 regulation of biological process;transport cytoplasm;extracellular;Golgi;membrane protein binding;structural molecule activity "Pf00400, Pf04053, Pf06957" 12847 ENSMUSG00000026553.17 Copa 1 COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic 0 High Q8CGC7 Bifunctional glutamate/proline--tRNA ligase OS=Mus musculus OX=10090 GN=Eprs1 PE=1 SV=4 0 37.033 12 13 26 13 1512 170 7.66 94855.26221 279778.7021 238749.252 4 5 5 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane catalytic activity;metal ion binding;nucleotide binding;protein binding;RNA binding "Pf00458, Pf00587, Pf00749, Pf01406, Pf03129, Pf03950, Pf09180, Pf14497" 107508 ENSMUSG00000026615.14 Eprs 1 Metabolic pathways; Aminoacyl-tRNA biosynthesis; Porphyrin and chlorophyll metabolism 0 High P26443 "Glutamate dehydrogenase 1, mitochondrial OS=Mus musculus OX=10090 GN=Glud1 PE=1 SV=1" 0 34.927 25 12 26 12 558 61.3 8 876808.9634 884643.062 418939.2534 658884.9197 7 6 2 8 metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding;protein binding "Pf00208, Pf02812" 14661 ENSMUSG00000021794.15 Glud1 14 Transcriptional activation of mitochondrial biogenesis; Amino acid synthesis and interconversion (transamination) "Metabolic pathways; Nitrogen metabolism; Proximal tubule bicarbonate reclamation; Carbon metabolism; D-Glutamine and D-glutamate metabolism; Alanine, aspartate and glutamate metabolism; Arginine biosynthesis" 0 High P49813 Tropomodulin-1 OS=Mus musculus OX=10090 GN=Tmod1 PE=1 SV=2 0 33.419 38 9 26 8 359 40.4 5.1 101402.3252 59232.82031 23424.20996 50051.88965 3 1 2 2 cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane;nucleus protein binding Pf03250 21916 ENSMUSG00000028328.13 Tmod1 4 Striated Muscle Contraction 0 High P62137 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit OS=Mus musculus OX=10090 GN=Ppp1ca PE=1 SV=1 0 36.57 39 10 26 10 330 37.5 6.33 2 2 1 2 2 1 823323.8271 594818.2759 615308.9043 306853.3271 10 8 3 7 cell division;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;nucleus catalytic activity;metal ion binding;protein binding Pf00149 19045 ENSMUSG00000040385.6; ENSMUSG00000096994.2 Ppp1ca 19; CHR_MG153_PATCH DARPP-32 events; Signaling by GPCR Oxytocin signaling pathway; mRNA surveillance pathway; Herpes simplex infection; Regulation of actin cytoskeleton; Dopaminergic synapse; Focal adhesion; Insulin signaling pathway; Long-term potentiation; Amphetamine addiction; Hippo signaling pathway; Platelet activation; Insulin resistance; Oocyte meiosis; Proteoglycans in cancer; cGMP-PKG signaling pathway; Alcoholism; cAMP signaling pathway; Vascular smooth muscle contraction; Adrenergic signaling in cardiomyocytes; Inflammatory mediator regulation of TRP channels 0 High Q91Y97 Fructose-bisphosphate aldolase B OS=Mus musculus OX=10090 GN=Aldob PE=1 SV=3 0 41.908 33 8 26 8 364 39.5 8.27 30016.25781 5275.38623 2 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;nucleus;vacuole catalytic activity;protein binding Pf00274 230163 ENSMUSG00000028307.9 Aldob 4 Fructose catabolism; Gluconeogenesis; Glycolysis Metabolic pathways; Biosynthesis of amino acids; Glycolysis / Gluconeogenesis; Pentose phosphate pathway; Carbon metabolism; Fructose and mannose metabolism 0 High Q91YZ8 Polyadenylate-binding protein OS=Mus musculus OX=10090 GN=Pabpc4 PE=1 SV=1 0 24.713 13 7 26 2 615 67.8 9.5 1 1 1 1 7147.632324 14524.66309 1 1 regulation of biological process cytoplasm;cytosol;nucleus RNA binding "Pf00076, Pf00658, Pf13893, Pf14259" 230721 ENSMUSG00000011257.19 Pabpc4 4 0 High Q99L88 Beta-1-syntrophin OS=Mus musculus OX=10090 GN=Sntb1 PE=1 SV=4 0 33.799 24 11 26 9 537 58 8.31 309169.2734 185961.6138 117377.3423 118234.8555 5 3 2 3 Met-loss+Acetyl [N-Term] cytoplasm;cytoskeleton;membrane protein binding;structural molecule activity "Pf00169, Pf00595" 20649 ENSMUSG00000060429.11 Sntb1 15 2 High Q8VCC2 Liver carboxylesterase 1 OS=Mus musculus OX=10090 GN=Ces1 PE=1 SV=1 0 36.32 25 11 26 9 565 62.6 6 74874.04492 20261.89258 406422.5547 3 1 2 cell organization and biogenesis;metabolic process;regulation of biological process endoplasmic reticulum;organelle lumen catalytic activity "Pf00135, Pf00756, Pf07859" 12623 ENSMUSG00000057074.6 Ces1g 8 Phase I - Functionalization of compounds 2 High Q8C804 Spindle and centriole-associated protein 1 OS=Mus musculus OX=10090 GN=Spice1 PE=1 SV=2 0 30.534 16 10 26 10 860 95.6 7.05 54507.50391 330987.2588 74882.27246 1 5 4 cell division;cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton 212514 ENSMUSG00000043065.12 Spice1 16 0 High P47915 60S ribosomal protein L29 OS=Mus musculus OX=10090 GN=Rpl29 PE=1 SV=2 0 20.08 26 5 26 5 160 17.6 11.84 165383.5032 51841.12988 41478.7627 99275.58057 3 2 1 2 cell proliferation;metabolic process ribosome structural molecule activity Pf01779 19944; 666642 ENSMUSG00000048758.14 Rpl29; Gm8210 9; 1 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High A0A0R4J0I9 Prolow-density lipoprotein receptor-related protein 1 OS=Mus musculus OX=10090 GN=Lrp1 PE=1 SV=1 0 47.468 5 16 25 16 4545 504.4 5.36 62588.37134 40992.22412 12252.73047 85279.94043 5 2 1 5 cell proliferation;development;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;endosome;membrane;nucleus metal ion binding;protein binding;receptor activity;RNA binding "Pf00057, Pf00058, Pf07645, Pf12662, Pf14670" 16971 ENSMUSG00000040249.15 Lrp1 10 Signaling by GPCR; Retinoid metabolism and transport; Scavenging of heme from plasma Alzheimer's disease; Malaria 0 High P43277 Histone H1.3 OS=Mus musculus OX=10090 GN=H1-3 PE=1 SV=2 0 19.609 23 6 25 1 221 22.1 11.03 1 1 25133.63086 158240.8281 1 1 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process chromosome;nucleus DNA binding;protein binding;RNA binding Pf00538 14957 ENSMUSG00000052565.6 Hist1h1d 13 0 High Q99K48 Non-POU domain-containing octamer-binding protein OS=Mus musculus OX=10090 GN=Nono PE=1 SV=3 0 23.851 21 8 25 7 473 54.5 8.95 75105.55615 27475.84375 16868.66943 4 1 2 defense response;metabolic process;regulation of biological process;response to stimulus membrane;nucleus DNA binding;protein binding;RNA binding "Pf00076, Pf08075, Pf13893, Pf14259" 53610 ENSMUSG00000031311.17 Nono X 0 High Q04857 Collagen alpha-1(VI) chain OS=Mus musculus OX=10090 GN=Col6a1 PE=1 SV=1 0 29.845 11 8 25 8 1025 108.4 5.36 4 1 4 1 4158386.184 4486535.775 2763420.316 4334531.965 8 7 2 6 cell differentiation;cell organization and biogenesis;response to stimulus extracellular;membrane protein binding "Pf00092, Pf01391, Pf13519, Pf13768" 12833 ENSMUSG00000001119.7 Col6a1 10 ECM proteoglycans; Collagen chain trimerization; Integrin cell surface interactions; NCAM1 interactions; Collagen degradation; Signaling by PDGF; Assembly of collagen fibrils and other multimeric structures Focal adhesion; Protein digestion and absorption; ECM-receptor interaction; PI3K-Akt signaling pathway 0 High Q8C7E7 Starch-binding domain-containing protein 1 OS=Mus musculus OX=10090 GN=Stbd1 PE=1 SV=1 0 25.459 37 9 25 9 338 36.1 5.99 15706.32715 9872.692383 1 1 metabolic process;transport cytosol;endoplasmic reticulum;membrane protein binding Pf00686 52331 ENSMUSG00000047963.7 Stbd1 5 Neutrophil degranulation 0 High Q9QYC0 Alpha-adducin OS=Mus musculus OX=10090 GN=Add1 PE=1 SV=2 0 37.149 26 11 25 10 735 80.6 5.9 38672.62012 34827.05078 20434.05664 4 1 1 cell differentiation;cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane;nucleus protein binding;RNA binding;structural molecule activity Pf00596 11518 ENSMUSG00000029106.14 Add1 5 Caspase-mediated cleavage of cytoskeletal proteins; Miscellaneous transport and binding events 1 High Q9D1R9 60S ribosomal protein L34 OS=Mus musculus OX=10090 GN=Rpl34 PE=1 SV=2 0 7.758 28 4 25 4 117 13.3 11.47 74293.31641 47389.26172 23465.69531 83094.81055 2 1 1 2 metabolic process mitochondrion;ribosome protein binding;RNA binding;structural molecule activity Pf01199 619547; 68436; 100043876 ENSMUSG00000062006.12 Rpl34-ps1; Rpl34; Gm4705 6; 3; 17 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High D3YUT3 40S ribosomal protein S19 (Fragment) OS=Mus musculus OX=10090 GN=Rps19 PE=1 SV=2 0 14.822 34 5 25 5 133 14.9 10.35 88388.28223 599361.5557 106437.3984 133183.292 2 3 1 3 metabolic process ribosome structural molecule activity Pf01090 ENSMUSG00000040952.16 7 0 High A0A140T8P2 Immunoglobulin kappa variable 6-20 (Fragment) OS=Mus musculus OX=10090 GN=Igkv6-20 PE=4 SV=2 0 16.323 32 3 25 2 115 12.6 5.01 2 2 4 4 998565.7656 839766.0078 103142.0156 118217.4219 2 2 1 2 "Pf00047, Pf07679, Pf07686, Pf13927" 108024 ENSMUSG00000076587.3 Igkv6-20 6 0 High Q641P0 Actin-related protein 3B OS=Mus musculus OX=10090 GN=Actr3b PE=1 SV=1 0 16.841 14 5 25 1 418 47.5 6.02 cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton nucleotide binding;protein binding Pf00022 242894 ENSMUSG00000056367.14 Actr3b 5 0 High G3X8Q5 Ceruloplasmin OS=Mus musculus OX=10090 GN=Cp PE=1 SV=1 0 42.37 18 12 25 12 1085 124.1 5.88 75544.95313 190613.0664 170140.7969 42943.04395 2 2 1 3 cellular homeostasis;metabolic process;response to stimulus;transport extracellular;membrane catalytic activity;metal ion binding;protein binding "Pf00394, Pf07731, Pf07732" 12870 ENSMUSG00000003617.16 Cp 3 0 High A0A075B5R1 Immunoglobulin heavy variable 5-17 (Fragment) OS=Mus musculus OX=10090 GN=Ighv5-17 PE=1 SV=1 0 12.263 35 3 24 2 117 12.9 8.28 3 2 5 3 695439.5625 336169.4453 92323.3125 2 2 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000095571.2 12 0 High Q9EPU0 Regulator of nonsense transcripts 1 OS=Mus musculus OX=10090 GN=Upf1 PE=1 SV=2 0 37.814 16 13 24 13 1124 123.9 6.61 36835.21777 234246.9199 8079.677734 121776.8269 6 7 1 6 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus chromosome;cytoplasm;cytosol;nucleus;spliceosomal complex catalytic activity;DNA binding;metal ion binding;nucleotide binding;protein binding;RNA binding "Pf04851, Pf09416, Pf13086, Pf13087, Pf13245, Pf13604" 19704 ENSMUSG00000058301.8 Upf1 8 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) mRNA surveillance pathway; RNA transport 0 High Q8BH44 Coronin-2B OS=Mus musculus OX=10090 GN=Coro2b PE=1 SV=2 0 32.24 25 11 24 11 480 54.9 8.27 14904.92725 16686.61914 16402.32813 30157.56543 2 1 1 3 cell organization and biogenesis cytoplasm;cytoskeleton;membrane protein binding "Pf00400, Pf08953, Pf08954" 235431 ENSMUSG00000041729.15 Coro2b 9 0 High P28230 Gap junction beta-1 protein OS=Mus musculus OX=10090 GN=Gjb1 PE=1 SV=3 0 34.985 14 4 24 4 283 32 8.95 49495.64063 12135.78809 1 1 cell communication;cell organization and biogenesis;transport cytoplasm;endoplasmic reticulum;membrane protein binding;transporter activity "Pf00029, Pf10582" 14618 ENSMUSG00000047797.14 Gjb1 X Oligomerization of connexins into connexons 0 High P51660 Peroxisomal multifunctional enzyme type 2 OS=Mus musculus OX=10090 GN=Hsd17b4 PE=1 SV=3 0 38.383 25 12 24 12 735 79.4 8.57 1 1 481455.5933 305346.1533 154615.6797 41254.16162 9 6 5 4 cell differentiation;metabolic process membrane;mitochondrion catalytic activity;protein binding "Pf00106, Pf01575, Pf02036, Pf08659, Pf13452, Pf13561, Pf14864" 15488 ENSMUSG00000024507.6 Hsd17b4 18 Beta-oxidation of pristanoyl-CoA; Beta-oxidation of very long chain fatty acids; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; alpha-linolenic acid (ALA) metabolism Metabolic pathways; Primary bile acid biosynthesis; Peroxisome 0 High G5E8E1 Leucine-rich repeat flightless-interacting protein 1 OS=Mus musculus OX=10090 GN=Lrrfip1 PE=1 SV=1 0 44.262 28 10 24 2 428 48.9 5.57 18935.14453 7631.779297 9421.396484 1 1 1 metabolic process;regulation of biological process cytoplasm;cytosol;membrane;nucleus DNA binding;protein binding "Pf04111, Pf09738" 16978 ENSMUSG00000026305.15 Lrrfip1 1 0 High A0A0U1RNT6 S-adenosylmethionine synthase OS=Mus musculus OX=10090 GN=Mat2a PE=1 SV=1 0 27.349 17 5 24 2 362 39.7 6.04 5738.166992 3346.269775 1 1 metabolic process catalytic activity;metal ion binding;nucleotide binding "Pf00438, Pf02772, Pf02773" ENSMUSG00000053907.10; ENSMUSG00000104463.2 6; CHR_MG184_PATCH 0 High P84089 Enhancer of rudimentary homolog OS=Mus musculus OX=10090 GN=Erh PE=1 SV=1 0 10.779 34 3 24 3 104 12.3 5.92 167483.7754 188624.8633 39322.3623 129991.9219 3 3 2 3 Met-loss+Acetyl [N-Term] cell differentiation;metabolic process;regulation of biological process membrane DNA binding;nucleotide binding;RNA binding Pf01133 13877 ENSMUSG00000021131.14; ENSMUSG00000063412.4 Erh 12; 8 0 High P15864 Histone H1.2 OS=Mus musculus OX=10090 GN=H1-2 PE=1 SV=2 0 21.92 28 7 24 2 212 21.3 11 1 1 1 1 511101.7598 248324.4072 69286.24121 202045.5625 7 3 2 3 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process chromosome;nucleus DNA binding;protein binding;RNA binding Pf00538 50708 ENSMUSG00000036181.2 Hist1h1c 13 5 High A0A0R4J0J8 Cytospin-A OS=Mus musculus OX=10090 GN=Specc1l PE=1 SV=1 0 34.97 12 10 23 10 1135 126.5 5.94 45587.65381 70647.77539 11875.84668 35434.03027 2 3 1 2 cell division;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;cytosol;membrane catalytic activity;motor activity;protein binding;structural molecule activity "Pf00038, Pf00307, Pf01576, Pf01920, Pf02463, Pf02932, Pf03251, Pf04111, Pf04156, Pf05667, Pf05701, Pf08317, Pf10186, Pf11971, Pf12128, Pf13166" 74392 ENSMUSG00000033444.14 Specc1l 10 0 High P43274 Histone H1.4 OS=Mus musculus OX=10090 GN=H1-4 PE=1 SV=2 0 18.358 23 5 23 2 219 22 11.11 1 1 107159.5957 305288.1641 10205.46094 79127.39258 2 2 1 2 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process chromosome;nucleus DNA binding;metal ion binding;nucleotide binding;protein binding;RNA binding Pf00538 50709 ENSMUSG00000051627.2 Hist1h1e 13 0 High Q9D826 Peroxisomal sarcosine oxidase OS=Mus musculus OX=10090 GN=Pipox PE=1 SV=1 0 27.379 22 7 23 7 390 43.8 7.55 16736.95508 10131.56543 34109.55176 1 1 2 metabolic process catalytic activity;protein binding "Pf00890, Pf01266, Pf13450" 19193 ENSMUSG00000017453.4 Pipox 11 Lysine catabolism "Metabolic pathways; Lysine degradation; Glycine, serine and threonine metabolism; Peroxisome" 0 High Q3UX10 Tubulin alpha chain-like 3 OS=Mus musculus OX=10090 GN=Tubal3 PE=2 SV=2 0 13.843 8 4 23 1 446 50 5.58 cell organization and biogenesis cytoplasm;cytoskeleton catalytic activity;nucleotide binding;structural molecule activity "Pf00091, Pf03953" 238463 ENSMUSG00000021216.6 Tubal3 13 Phagosome; Gap junction; Apoptosis 0 High Q91VR5 ATP-dependent RNA helicase DDX1 OS=Mus musculus OX=10090 GN=Ddx1 PE=1 SV=1 0 29.696 18 12 23 12 740 82.4 7.21 94791.3252 115527.791 58386.83838 5 5 4 development;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;nucleus catalytic activity;DNA binding;nucleotide binding;protein binding;RNA binding "Pf00270, Pf00271, Pf00622" 104721 ENSMUSG00000037149.9 Ddx1 12 0 High A0A140T8P1 Immunoglobulin kappa variable 6-14 (Fragment) OS=Mus musculus OX=10090 GN=Igkv6-14 PE=4 SV=2 0 14.985 34 4 23 3 115 12.8 6.51 2 1 4 1 1926233.883 247701.4375 61609.42578 61329.16016 3 1 1 1 structural molecule activity "Pf00047, Pf01410, Pf07679, Pf07686" 667881 ENSMUSG00000096844.1 Igkv6-14 6 0 High P10605 Cathepsin B OS=Mus musculus OX=10090 GN=Ctsb PE=1 SV=2 0 18.509 17 5 23 5 339 37.3 5.91 44350.81787 79808.31934 65876.83215 3 3 3 cell differentiation;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;extracellular;membrane;mitochondrion;vacuole catalytic activity;protein binding "Pf00112, Pf08127" 13030 ENSMUSG00000021939.7 Ctsb 14 Neutrophil degranulation; Collagen degradation; Trafficking and processing of endosomal TLR NOD-like receptor signaling pathway; Lysosome; Antigen processing and presentation; Renin secretion; Apoptosis 0 High Q8CDM8 Protein FAM160B1 OS=Mus musculus OX=10090 GN=Fam160b1 PE=1 SV=2 0 44.296 27 13 23 13 764 86 5.25 63223.11914 8140.274414 84065.50781 19150.3457 3 1 1 1 Pf10257 226252 ENSMUSG00000033478.4 Fam160b1 19 0 High O08807 Peroxiredoxin-4 OS=Mus musculus OX=10090 GN=Prdx4 PE=1 SV=1 0 24.592 18 4 23 2 274 31 7.15 3103.770752 35653.52734 1 1 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process cytoplasm;cytosol;endoplasmic reticulum;mitochondrion;nucleus antioxidant activity;catalytic activity;protein binding "Pf00578, Pf08534, Pf10417" 53381 ENSMUSG00000025289.15 Prdx4 X Neutrophil degranulation 0 High P41105 60S ribosomal protein L28 OS=Mus musculus OX=10090 GN=Rpl28 PE=1 SV=2 0 11.181 28 4 23 4 137 15.7 12.02 4120.642578 107830.875 19858.20703 1 1 1 Met-loss+Acetyl [N-Term] metabolic process;regulation of biological process membrane;ribosome RNA binding;structural molecule activity Pf01778 19943 ENSMUSG00000030432.12 Rpl28 7 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High P19973 Lymphocyte-specific protein 1 OS=Mus musculus OX=10090 GN=Lsp1 PE=1 SV=2 0 39.639 42 8 23 8 330 36.7 4.82 22638.28174 10187.96387 3 1 Met-loss+Acetyl [N-Term] cell death;cell organization and biogenesis;defense response;regulation of biological process;response to stimulus membrane protein binding;signal transducer activity Pf02029 16985 ENSMUSG00000018819.10 Lsp1 7 Tuberculosis 0 High P10639 Thioredoxin OS=Mus musculus OX=10090 GN=Txn PE=1 SV=3 0 11.479 41 4 22 4 105 11.7 4.92 1 1 133890.1011 66137.92188 44110.69922 77193.08008 2 1 1 2 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;extracellular;mitochondrion;nucleus antioxidant activity;catalytic activity;protein binding;RNA binding "Pf00085, Pf13098, Pf13899, Pf13905" 22166 ENSMUSG00000028367.5 Txn1 4 Interconversion of nucleotide di- and triphosphates; Protein repair; Detoxification of Reactive Oxygen Species; TP53 Regulates Metabolic Genes; Oxidative Stress Induced Senescence; The NLRP3 inflammasome NOD-like receptor signaling pathway 0 High O08528 Hexokinase-2 OS=Mus musculus OX=10090 GN=Hk2 PE=1 SV=1 0 38.522 18 12 22 12 917 102.5 6.11 618185.5382 225742.0781 56739.31836 350569.4263 9 4 2 8 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytosol;membrane;mitochondrion catalytic activity;nucleotide binding;protein binding "Pf00349, Pf03727" 15277 ENSMUSG00000000628.10 Hk2 6 Glycolysis "Neomycin, kanamycin and gentamicin biosynthesis; Type II diabetes mellitus; Carbohydrate digestion and absorption; Insulin signaling pathway; Metabolic pathways; Amino sugar and nucleotide sugar metabolism; Starch and sucrose metabolism; Glycolysis / Gluconeogenesis; HIF-1 signaling pathway; Carbon metabolism; Fructose and mannose metabolism; Galactose metabolism; Central carbon metabolism in cancer" 0 High Q64459 Cytochrome P450 3A11 OS=Mus musculus OX=10090 GN=Cyp3a11 PE=1 SV=1 0 27.099 29 10 22 10 504 57.8 8.82 43684.41016 12795.51953 121887.3125 4430.197266 1 1 2 1 metabolic process endoplasmic reticulum;membrane catalytic activity;metal ion binding Pf00067 13112 ENSMUSG00000056035.8 Cyp3a11 5 Aflatoxin activation and detoxification; Miscellaneous substrates; Xenobiotics Steroid hormone biosynthesis; Retinol metabolism; Metabolic pathways; Linoleic acid metabolism; Chemical carcinogenesis 0 High P26039 Talin-1 OS=Mus musculus OX=10090 GN=Tln1 PE=1 SV=2 0 54.065 10 16 22 16 2541 269.7 6.18 1 1 1882994.219 7034112.971 1175156.724 1416542.492 12 11 8 9 cell organization and biogenesis;regulation of biological process;response to stimulus cell surface;cytoplasm;cytoskeleton;membrane protein binding;structural molecule activity "Pf00373, Pf01608, Pf02174, Pf08913, Pf09141, Pf09379" 21894 ENSMUSG00000028465.16 Tln1 4 p130Cas linkage to MAPK signaling for integrins; GRB2:SOS provides linkage to MAPK signaling for Integrins ; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion; Platelet degranulation ; Smooth Muscle Contraction Focal adhesion; Platelet activation; HTLV-I infection; Rap1 signaling pathway 0 High Q9QYB8 Beta-adducin OS=Mus musculus OX=10090 GN=Add2 PE=1 SV=4 0 24.226 17 8 22 7 725 80.6 6.21 23228.31885 13138.97168 33771.15234 8703.733398 2 1 1 1 Met-loss+Acetyl [N-Term] cell organization and biogenesis;cellular component movement;regulation of biological process;transport cytoplasm;cytoskeleton;membrane protein binding;structural molecule activity "Pf00596, Pf03344" 11519 ENSMUSG00000030000.10 Add2 6 Miscellaneous transport and binding events 0 High A2AS89 "Agmatinase, mitochondrial OS=Mus musculus OX=10090 GN=Agmat PE=1 SV=1" 0 31.779 37 7 22 7 358 38.2 7.87 36760.40747 39176.80859 29547.50391 2 1 1 metabolic process mitochondrion catalytic activity;metal ion binding Pf00491 75986 ENSMUSG00000040706.4 Agmat 4 Agmatine biosynthesis Arginine and proline metabolism; Metabolic pathways 0 High Q61703 Inter-alpha-trypsin inhibitor heavy chain H2 OS=Mus musculus OX=10090 GN=Itih2 PE=1 SV=1 0 35.402 15 10 22 10 946 105.9 7.27 126830.6367 80992.00781 12906.71973 22485.87695 2 1 1 1 metabolic process;regulation of biological process extracellular enzyme regulator activity "Pf00092, Pf06668, Pf08487, Pf10138, Pf13519, Pf13768" 16425 Itih2 2 0 High Q80UW2 F-box only protein 2 OS=Mus musculus OX=10090 GN=Fbxo2 PE=1 SV=1 0 22.904 43 7 22 7 297 33.7 4.28 25089.94531 67095.79688 1 2 metabolic process;regulation of biological process cytoplasm;cytosol;endoplasmic reticulum;membrane catalytic activity;protein binding Pf04300 230904 ENSMUSG00000041556.8 Fbxo2 4 Neddylation; Antigen processing: Ubiquitination & Proteasome degradation Ubiquitin mediated proteolysis; Protein processing in endoplasmic reticulum 0 High A0A338P6C7 Synaptojanin-1 (Fragment) OS=Mus musculus OX=10090 GN=Synj1 PE=1 SV=1 0 25.643 54 6 22 1 242 24.8 5.67 0 High Q9CZN7 "Serine hydroxymethyltransferase, mitochondrial OS=Mus musculus OX=10090 GN=Shmt2 PE=1 SV=1" 0 20.647 18 8 22 8 504 55.7 8.47 44112.4082 26815.80969 46475.58447 5 4 4 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane;mitochondrion;nucleus;organelle lumen catalytic activity;protein binding Pf00464 108037 ENSMUSG00000025403.5 Shmt2 10 Metabolism of folate and pterines "Metabolic pathways; Biosynthesis of amino acids; Glycine, serine and threonine metabolism; Antifolate resistance; Carbon metabolism; One carbon pool by folate; Glyoxylate and dicarboxylate metabolism" 0 High P82349 Beta-sarcoglycan OS=Mus musculus OX=10090 GN=Sgcb PE=1 SV=1 0 59.087 41 11 22 11 320 34.9 8.6 36131.04248 199462.8262 16475.86719 188121.5088 3 4 1 8 Met-loss+Acetyl [N-Term] cell organization and biogenesis cytoplasm;cytoskeleton;membrane Pf04790 24051 ENSMUSG00000029156.11 Sgcb 5 Hypertrophic cardiomyopathy (HCM); Arrhythmogenic right ventricular cardiomyopathy (ARVC); Dilated cardiomyopathy; Viral myocarditis 0 High Q6ZWY3 40S ribosomal protein S27-like OS=Mus musculus OX=10090 GN=Rps27l PE=1 SV=3 0 18.157 39 4 22 4 84 9.5 9.45 248651.8438 34359.03516 443224.9624 1 1 5 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus nucleus;ribosome enzyme regulator activity;metal ion binding;RNA binding;structural molecule activity;translation regulator activity Pf01667 67941 ENSMUSG00000036781.13 Rps27l 9 0 High P09055 Integrin beta-1 OS=Mus musculus OX=10090 GN=Itgb1 PE=1 SV=1 0 31.335 14 9 22 9 798 88.2 5.94 45700.89795 60721.27124 23097.86816 74880.09326 2 2 2 4 cell differentiation;cell growth;cell organization and biogenesis;cellular component movement;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;endosome;membrane metal ion binding;protein binding;receptor activity "Pf00362, Pf07965, Pf08725" 16412 ENSMUSG00000025809.15 Itgb1 8 ECM proteoglycans; Molecules associated with elastic fibres; Laminin interactions; Integrin cell surface interactions; Localization of the PINCH-ILK-PARVIN complex to focal adhesions; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; MET interacts with TNS proteins; MET activates PTK2 signaling; Signal transduction by L1; Syndecan interactions; Fibronectin matrix formation; Basigin interactions Leukocyte transendothelial migration; Hypertrophic cardiomyopathy (HCM); Regulation of actin cytoskeleton; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Focal adhesion; Toxoplasmosis; Platelet activation; Small cell lung cancer; Dilated cardiomyopathy; Axon guidance; Cell adhesion molecules (CAMs); Phagosome; Pertussis; Proteoglycans in cancer; Rap1 signaling pathway; Pathways in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway; Leishmaniasis; Bacterial invasion of epithelial cells 0 High A0A140T8N3 Immunoglobulin kappa chain variable 13-84 (Fragment) OS=Mus musculus OX=10090 GN=Igkv13-84 PE=4 SV=2 0 15.199 32 3 21 2 115 12.6 6.51 3 2 6 2 2825369.945 1928999.473 163606.9922 3 3 2 "Pf00047, Pf07686" 692152 ENSMUSG00000076538.1 Igkv13-84 6 1 High Q8K3B1 F-box/SPRY domain-containing protein 1 OS=Mus musculus OX=10090 GN=Fbxo45 PE=1 SV=2 0 16.3 27 7 21 7 286 30.6 7.85 1 1 446327.8613 90635.875 90807.96875 4 2 2 cell organization and biogenesis;cellular component movement;development;metabolic process;response to stimulus membrane protein binding "Pf00622, Pf00646, Pf12937" 268882 ENSMUSG00000035764.5 Fbxo45 16 0 High Q8BKI2 Trinucleotide repeat-containing gene 6B protein OS=Mus musculus OX=10090 GN=Tnrc6b PE=1 SV=2 0 26.499 7 8 21 8 1810 191.8 6.3 36957.34351 27299.85156 26124.37939 4 1 2 regulation of biological process cytoplasm RNA binding "Pf10427, Pf13893" 213988 ENSMUSG00000047888.9 Tnrc6b 15 Post-transcriptional silencing by small RNAs 0 High D3Z1S8 40S ribosomal protein S5 (Fragment) OS=Mus musculus OX=10090 GN=Rps5 PE=1 SV=1 0 16.797 44 5 21 5 189 21.1 9.52 40598.18945 51524.98535 83229.36133 27369.58154 2 2 2 2 Met-loss+Acetyl [N-Term] metabolic process ribosome RNA binding;structural molecule activity Pf00177 ENSMUSG00000012848.15 7 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" 0 High Q07076 Annexin A7 OS=Mus musculus OX=10090 GN=Anxa7 PE=1 SV=2 0 30.797 28 11 21 11 463 49.9 6.18 330240.7188 59673.94922 125989.7147 8 4 3 cell differentiation;cell organization and biogenesis;cell proliferation;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cytosol;membrane;nucleus metal ion binding;protein binding;RNA binding Pf00191 11750 ENSMUSG00000021814.16 Anxa7 14 0 High Q3UEP4 UDP-glucuronosyltransferase OS=Mus musculus OX=10090 GN=Ugt2b36 PE=1 SV=1 0 48.175 31 11 21 9 530 61 8.25 17116.49414 6100.069824 6375.182617 4028.477051 1 1 1 1 metabolic process membrane catalytic activity "Pf00201, Pf04101, Pf13528" 231396 ENSMUSG00000070704.10 Ugt2b36 5 Steroid hormone biosynthesis; Drug metabolism - cytochrome P450; Retinol metabolism; Metabolic pathways; Drug metabolism - other enzymes; Ascorbate and aldarate metabolism; Chemical carcinogenesis; Porphyrin and chlorophyll metabolism; Pentose and glucuronate interconversions; Metabolism of xenobiotics by cytochrome P450 0 High Q64442 Sorbitol dehydrogenase OS=Mus musculus OX=10090 GN=Sord PE=1 SV=3 0 35.631 27 7 21 7 357 38.2 7.02 29669.8186 2001.817139 21352.19873 2 1 2 Met-loss+Acetyl [N-Term] cellular component movement;metabolic process;response to stimulus membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00107, Pf08240" 20322 ENSMUSG00000027227.7 Sord 2 Fructose biosynthesis; Catabolism of glucuronate to xylulose-5-phosphate Metabolic pathways; Fructose and mannose metabolism; Pentose and glucuronate interconversions 0 High P80315 T-complex protein 1 subunit delta OS=Mus musculus OX=10090 GN=Cct4 PE=1 SV=3 0 20.986 22 9 21 8 539 58 8.02 171623.4663 39265.5 78778.95605 4 2 3 metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;cytosol nucleotide binding;protein binding;RNA binding Pf00118 12464 ENSMUSG00000007739.10 Cct4 11 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Association of TriC/CCT with target proteins during biosynthesis 1 High Q9WV69 Dematin OS=Mus musculus OX=10090 GN=Dmtn PE=1 SV=1 0 25.107 26 8 21 8 405 45.4 8.41 7845.189941 55563.97656 73256.71875 1 1 1 cell organization and biogenesis;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;membrane protein binding Pf02209 13829 Dmtn; Epb4.9 14 Miscellaneous transport and binding events 0 High A0A075B5R4 Immunoglobulin heavy variable 14-1 (Fragment) OS=Mus musculus OX=10090 GN=Ighv14-1 PE=4 SV=1 0 16.333 38 4 21 2 117 13 4.93 2 2 3 3 988373.8594 292911.0859 23409.05664 91106.67383 2 2 1 2 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding "Pf00047, Pf07686" ENSMUSG00000094509.1 12 0 High P62849 40S ribosomal protein S24 OS=Mus musculus OX=10090 GN=Rps24 PE=1 SV=1 0 19.216 35 5 21 5 133 15.4 10.78 134565.0283 154937.9688 118880.0322 4 3 3 Acetyl [N-Term] metabolic process membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity Pf01282 20088; 102642752 ENSMUSG00000025290.16 Rps24; LOC677113; LOC102642752 14; 16 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High Q9JHU4 Cytoplasmic dynein 1 heavy chain 1 OS=Mus musculus OX=10090 GN=Dync1h1 PE=1 SV=2 0 31.36 4 14 21 14 4644 531.7 6.42 252854.4626 128760.6802 75973.78149 9 6 6 cell division;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;membrane catalytic activity;motor activity;nucleotide binding;protein binding;RNA binding "Pf00769, Pf03028, Pf03915, Pf04156, Pf07246, Pf07728, Pf08385, Pf08393, Pf12774, Pf12775, Pf12777, Pf12780, Pf12781, Pf13173, Pf13207, Pf13401" 13424 ENSMUSG00000018707.13 Dync1h1 12 Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; COPI-mediated anterograde transport; Regulation of PLK1 Activity at G2/M Transition; Neutrophil degranulation; Recruitment of NuMA to mitotic centrosomes; HSP90 chaperone cycle for steroid hormone receptors (SHR); Resolution of Sister Chromatid Cohesion; Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal; COPI-independent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; RHO GTPases Activate Formins; MHC class II antigen presentation Phagosome; Salmonella infection; Vasopressin-regulated water reabsorption 0 High P04919 Band 3 anion transport protein OS=Mus musculus OX=10090 GN=Slc4a1 PE=1 SV=1 0 45.744 17 8 21 8 929 103.1 5.45 262678.418 34636.27734 2188.990723 4 1 1 cell organization and biogenesis;cellular homeostasis;regulation of biological process;response to stimulus;transport cell surface;cytoskeleton;membrane protein binding;transporter activity "Pf00955, Pf07565" 20533 ENSMUSG00000006574.15 Slc4a1 11 Erythrocytes take up carbon dioxide and release oxygen; Erythrocytes take up oxygen and release carbon dioxide; Bicarbonate transporters Collecting duct acid secretion 0 High P57722 Poly(rC)-binding protein 3 OS=Mus musculus OX=10090 GN=Pcbp3 PE=1 SV=3 0 14.724 15 4 21 1 371 39.3 7.52 regulation of biological process cytoplasm;cytosol;nucleus DNA binding;RNA binding "Pf00013, Pf13014" 59093 ENSMUSG00000001120.15 Pcbp3 10 0 High P58137 Acyl-coenzyme A thioesterase 8 OS=Mus musculus OX=10090 GN=Acot8 PE=1 SV=1 0 19.98 32 6 20 6 320 35.8 7.64 29045.33887 2 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;mitochondrion;organelle lumen catalytic activity;protein binding "Pf02551, Pf13622" 170789 ENSMUSG00000017307.15 Acot8 2 Beta-oxidation of pristanoyl-CoA; Beta-oxidation of very long chain fatty acids; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; alpha-linolenic acid (ALA) metabolism Metabolic pathways; Primary bile acid biosynthesis; Peroxisome 0 High Q9Z2T6 "Keratin, type II cuticular Hb5 OS=Mus musculus OX=10090 GN=Krt85 PE=1 SV=2" 0 17.687 10 5 20 1 507 55.7 6.42 1 1 22145.52197 359114.8291 22739.51172 57126.70313 3 2 1 1 structural molecule activity Pf00038 53622 Krt85 15 3 High Q9DC63 F-box only protein 3 OS=Mus musculus OX=10090 GN=Fbxo3 PE=1 SV=1 0 28.333 19 7 20 7 480 55.2 5.02 43110.12744 115548.8621 57987.00244 3 3 5 regulation of biological process cytosol;nucleus protein binding "Pf00646, Pf04379, Pf06881, Pf09346, Pf12937" 57443 ENSMUSG00000027180.12 Fbxo3 2 0 High A2A8U2 Transmembrane protein 201 OS=Mus musculus OX=10090 GN=Tmem201 PE=1 SV=1 0 24.01 15 8 20 8 664 72.5 9.2 36395.42383 19917.28906 2 3 cell organization and biogenesis;cellular component movement membrane;nucleus protein binding "Pf09779, Pf10476" 230917 ENSMUSG00000044700.15 Tmem201 4 0 High Q8BGS1 Band 4.1-like protein 5 OS=Mus musculus OX=10090 GN=Epb41l5 PE=1 SV=1 0 40.327 21 9 20 9 731 81.6 6.39 20531.29834 105090.375 10499.81055 29693.79102 2 2 1 1 cell growth;cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane protein binding;structural molecule activity "Pf00373, Pf08736, Pf09379, Pf09380" 226352 ENSMUSG00000026383.14 Epb4.1l5; Epb41l5 1 Neurexins and neuroligins 0 Medium E9Q0B5 Fc fragment of IgG-binding protein OS=Mus musculus OX=10090 GN=Fcgbp PE=1 SV=1 0.013 1.946 0 1 20 1 2583 275 5.03 1 1 2 2 399057.8438 1168519.875 186144.5625 381244.3438 1 1 1 1 protein binding "Pf00094, Pf01826, Pf08742, Pf12714" ENSMUSG00000047730.17 7 0 High Q8VCU1 Carboxylesterase 3B OS=Mus musculus OX=10090 GN=Ces3b PE=1 SV=2 0 12.602 12 5 20 2 571 63.3 5.92 metabolic process endoplasmic reticulum;organelle lumen catalytic activity "Pf00135, Pf00326, Pf00756, Pf07859" 13909 ENSMUSG00000062181.14 Ces3b 8 Phase I - Functionalization of compounds; LDL clearance 0 High A0A1D5RLW5 60S ribosomal protein L18a OS=Mus musculus OX=10090 GN=Rpl18a PE=1 SV=1 0 13.606 31 4 20 4 147 17.4 10.89 1 1 30867.20801 13916.30078 31887.64258 49612.98438 2 1 1 2 metabolic process ribosome structural molecule activity Pf01775 ENSMUSG00000045128.9 8 0 High Q9D1Q6 Endoplasmic reticulum resident protein 44 OS=Mus musculus OX=10090 GN=Erp44 PE=1 SV=1 0 39.602 22 7 20 7 406 46.8 5.27 28222.30859 65478.11133 96334.65527 2 1 4 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cell surface;endoplasmic reticulum;membrane;organelle lumen catalytic activity;metal ion binding;protein binding "Pf00085, Pf01216, Pf07449, Pf13098, Pf13848" 76299 ENSMUSG00000028343.10 Erp44 4 Neutrophil degranulation 0 High F7AEH4 40S ribosomal protein S12 OS=Mus musculus OX=10090 GN=Rps12 PE=1 SV=1 0 19.213 47 4 20 4 137 15.2 8.35 116158.9966 210447.7441 44685.29688 148121.7351 3 3 1 4 Met-loss+Acetyl [N-Term] metabolic process cytosol;membrane;ribosome RNA binding;structural molecule activity Pf01248 20042 ENSMUSG00000061983.7 Rps12 10 0 High F6SPK0 Ubiquitin-conjugating enzyme E2 J1 (Fragment) OS=Mus musculus OX=10090 GN=Ube2j1 PE=1 SV=1 0 35.115 32 7 20 7 262 28.9 7.25 19468.63257 7508.957031 207711.2344 2 1 4 metabolic process;regulation of biological process membrane Pf00179 ENSMUSG00000028277.13 4 0 High Q8CC88 von Willebrand factor A domain-containing protein 8 OS=Mus musculus OX=10090 GN=Vwa8 PE=1 SV=2 0 27.987 9 13 20 13 1905 213.3 6.6 347330.1738 200621.3721 87368.76465 214778.9063 10 5 4 9 extracellular;mitochondrion catalytic activity;nucleotide binding "Pf00092, Pf07728, Pf13191, Pf13519, Pf13521" 219189 ENSMUSG00000058997.7 Vwa8 14 0 High Q9R0P5 Destrin OS=Mus musculus OX=10090 GN=Dstn PE=1 SV=3 0 28.806 48 8 20 7 165 18.5 7.97 8589.239258 17092.50342 1 2 Met-loss+Acetyl [N-Term] cell organization and biogenesis;cellular component movement;regulation of biological process cytoplasm;cytoskeleton protein binding Pf00241 56431 ENSMUSG00000015932.8 Dstn 2 0 High Q8CAS9 Protein mono-ADP-ribosyltransferase PARP9 OS=Mus musculus OX=10090 GN=Parp9 PE=1 SV=2 0 42.856 17 11 20 11 866 96.6 7.09 49088.05762 58896.74316 7266.23877 3 4 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;enzyme regulator activity;nucleotide binding;protein binding Pf01661 80285 Parp9 16 Nicotinamide salvaging 0 Medium Q6AXE3 ATP-binding cassette sub-family A member 3 OS=Mus musculus OX=10090 GN=Abca3 PE=1 SV=1 0.013 2.026 1 1 20 1 1449 163.4 7.83 1 1 1 1 3336418.808 2711123.918 2472860.645 2146122.477 1 1 1 1 transport membrane catalytic activity;nucleotide binding;transporter activity "Pf00005, Pf03193, Pf12698, Pf13304, Pf13476" 27410 ENSMUSG00000024130.15 Abca3 17 ABC transporters 0 High Q6ZWV7 60S ribosomal protein L35 OS=Mus musculus OX=10090 GN=Rpl35 PE=1 SV=1 0 10.533 26 3 20 3 123 14.5 11.05 262555.2549 421782.79 204311.8125 272546.5459 3 2 1 3 metabolic process;response to stimulus membrane;ribosome RNA binding;structural molecule activity Pf00831 66489 ENSMUSG00000078193.2; ENSMUSG00000062997.6 Rpl35 2; 1 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q99KG5 Lipolysis-stimulated lipoprotein receptor OS=Mus musculus OX=10090 GN=Lsr PE=1 SV=1 0 35.562 24 10 20 10 594 66.1 6.54 80092.69312 162592.4966 39601.00781 177998.0946 2 2 1 2 regulation of biological process;transport membrane protein binding;receptor activity 54135 ENSMUSG00000001247.16 Lsr 7 0 High O88587 Catechol O-methyltransferase OS=Mus musculus OX=10090 GN=Comt PE=1 SV=2 0 30.592 60 12 20 12 265 29.5 5.83 33678.44922 7056.425293 15904.92578 36290.51953 2 1 1 2 cell communication;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion catalytic activity;metal ion binding "Pf01596, Pf12847, Pf13578, Pf13659" 12846 ENSMUSG00000000326.12; ENSMUSG00000098892.8 Comt 16; CHR_MG3833_MG4220_PATCH Enzymatic degradation of Dopamine by monoamine oxidase; Enzymatic degradation of dopamine by COMT; Methylation Steroid hormone biosynthesis; Dopaminergic synapse; Metabolic pathways; Tyrosine metabolism 0 High Q9CZS1 "Aldehyde dehydrogenase X, mitochondrial OS=Mus musculus OX=10090 GN=Aldh1b1 PE=1 SV=1" 0 20.222 17 7 20 6 519 57.5 7.02 12349.33594 5042.603516 1 1 metabolic process mitochondrion;organelle lumen catalytic activity Pf00171 72535 ENSMUSG00000035561.5 Aldh1b1 4 Ethanol oxidation "Histidine metabolism; Pyruvate metabolism; Arginine and proline metabolism; Tryptophan metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Lysine degradation; Fatty acid degradation; Glycolysis / Gluconeogenesis; beta-Alanine metabolism; Ascorbate and aldarate metabolism; Glycerolipid metabolism; Pentose and glucuronate interconversions" 0 High P26231 Catenin alpha-1 OS=Mus musculus OX=10090 GN=Ctnna1 PE=1 SV=1 0 29.951 15 10 20 10 906 100 6.23 121644.2703 247511.0625 22280.26172 59751.24023 4 4 1 2 Met-loss+Acetyl [N-Term] cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;Golgi;membrane protein binding;RNA binding;structural molecule activity Pf01044 12385 ENSMUSG00000037815.6 Ctnna1 18 VEGFR2 mediated vascular permeability; RHO GTPases activate IQGAPs; Adherens junctions interactions; CDO in myogenesis Leukocyte transendothelial migration; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Endometrial cancer; Hippo signaling pathway; Adherens junction; Pathways in cancer; Tight junction; Bacterial invasion of epithelial cells 0 High E9Q6D8 Complement component 6 OS=Mus musculus OX=10090 GN=C6 PE=1 SV=2 0 44.656 25 15 19 15 934 104.6 6.24 214182.1094 123419.3896 14260.49707 3 3 2 0 High A0A075B5P9 Immunoglobulin heavy variable 5-4 (Fragment) OS=Mus musculus OX=10090 GN=Ighv5-4 PE=4 SV=1 0 10.053 19 2 19 1 117 13 8.6 2 2 3 4 246003.7813 872264.375 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000095612.2 LOC674129 12 0 High P10630 Eukaryotic initiation factor 4A-II OS=Mus musculus OX=10090 GN=Eif4a2 PE=1 SV=2 0 20.015 15 5 19 2 407 46.4 5.48 1765.114014 1 metabolic process;regulation of biological process cytoplasm catalytic activity;DNA binding;nucleotide binding;RNA binding "Pf00270, Pf00271, Pf04851" 13682 ENSMUSG00000022884.14 Eif4a2 16 L13a-mediated translational silencing of Ceruloplasmin expression; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ISG15 antiviral mechanism; Translation initiation complex formation; Deadenylation of mRNA RNA transport 0 High Q8VCG4 Complement component C8 gamma chain OS=Mus musculus OX=10090 GN=C8g PE=1 SV=1 0 59.771 58 8 19 8 202 22.5 9.25 463094.2815 32879.84277 2 1 defense response;metabolic process;regulation of biological process;response to stimulus extracellular protein binding Pf00061 69379 ENSMUSG00000015083.11 C8g 2 Regulation of Complement cascade; Terminal pathway of complement Complement and coagulation cascades; Prion diseases; Systemic lupus erythematosus; Amoebiasis 0 High Q9R0N0 Galactokinase OS=Mus musculus OX=10090 GN=Galk1 PE=1 SV=2 0 32.305 30 8 19 8 392 42.3 5.26 188718.209 41329.32813 5569.433105 29890.86963 4 3 1 3 metabolic process cytoplasm;membrane catalytic activity;nucleotide binding;protein binding "Pf08544, Pf10509" 14635 ENSMUSG00000020766.4 Galk1 11 Galactose catabolism Metabolic pathways; Amino sugar and nucleotide sugar metabolism; Galactose metabolism 0 High P18529 Ig heavy chain V region 5-76 OS=Mus musculus OX=10090 PE=1 SV=1 0 5.795 15 2 19 1 117 13 8.91 1 1 2 2 43059.36719 141733.4375 31502.74414 104543.1094 1 1 1 1 Pf07686 0 High Q60598 Src substrate cortactin OS=Mus musculus OX=10090 GN=Cttn PE=1 SV=2 0 33.442 31 12 19 12 546 61.2 5.4 26346.25391 39733.74219 60287.4375 32553.375 1 1 1 1 cell organization and biogenesis;cellular component movement;regulation of biological process;transport cytoplasm;cytoskeleton;cytosol;Golgi;membrane protein binding "Pf00018, Pf02218, Pf07653, Pf14604" 13043 ENSMUSG00000031078.15 Cttn 7 Clathrin-mediated endocytosis Proteoglycans in cancer; Tight junction; Bacterial invasion of epithelial cells 0 High A0A0A0MQM0 Eukaryotic translation initiation factor 5A (Fragment) OS=Mus musculus OX=10090 GN=Eif5a PE=1 SV=1 0 23.936 34 4 19 4 149 16.3 5 83509.69678 25661.76172 37092.75781 4 1 1 cell death;cellular homeostasis;metabolic process;regulation of biological process;transport cytoplasm;endoplasmic reticulum;membrane;nucleus protein binding;RNA binding Pf01287 276770 ENSMUSG00000078812.10 Eif5a 11 0 High Q8BK67 Protein RCC2 OS=Mus musculus OX=10090 GN=Rcc2 PE=1 SV=1 0 27.427 18 7 19 7 520 55.9 8.72 19872.71509 50036.96631 26936.25098 1 2 2 cell division;cell organization and biogenesis;regulation of biological process;response to stimulus chromosome;cytoplasm;cytoskeleton;membrane;nucleus protein binding;RNA binding "Pf00415, Pf13540" 108911 ENSMUSG00000040945.13 Rcc2 4 Resolution of Sister Chromatid Cohesion; Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal; Separation of Sister Chromatids; RHO GTPases Activate Formins 0 High P80316 T-complex protein 1 subunit epsilon OS=Mus musculus OX=10090 GN=Cct5 PE=1 SV=1 0 27.174 24 9 19 8 541 59.6 6.02 145584.4509 88432.07324 24482.93799 6 3 2 Met-loss+Acetyl [N-Term] metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol nucleotide binding;protein binding;RNA binding Pf00118 12465 ENSMUSG00000022234.14 Cct5 15 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Association of TriC/CCT with target proteins during biosynthesis 0 High P29788 Vitronectin OS=Mus musculus OX=10090 GN=Vtn PE=1 SV=2 0 31.941 20 6 19 6 478 54.8 5.88 65785.16943 105171.6484 188265.582 16120.83252 3 3 2 2 cell differentiation;cell organization and biogenesis;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;extracellular;organelle lumen protein binding;receptor activity "Pf00045, Pf01033" 22370 ENSMUSG00000017344.4 Vtn 11 Regulation of Complement cascade; ECM proteoglycans; Molecules associated with elastic fibres; Syndecan interactions; Integrin cell surface interactions Focal adhesion; Complement and coagulation cascades; Proteoglycans in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway 0 High Q02013 Aquaporin-1 OS=Mus musculus OX=10090 GN=Aqp1 PE=1 SV=3 0 17.307 11 2 19 2 269 28.8 7.43 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;membrane;nucleus protein binding;transporter activity Pf00230 11826 ENSMUSG00000004655.5 Aqp1 6 Erythrocytes take up carbon dioxide and release oxygen; Vasopressin regulates renal water homeostasis via Aquaporins; Passive transport by Aquaporins; Erythrocytes take up oxygen and release carbon dioxide Proximal tubule bicarbonate reclamation; Bile secretion; Renin secretion 0 High Q7TNG8 "Probable D-lactate dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Ldhd PE=1 SV=1" 0 31.958 26 7 19 7 484 51.8 6.62 1 1 532784.4351 941473.1699 337366.1514 4 3 3 metabolic process membrane;mitochondrion catalytic activity;nucleotide binding;protein binding "Pf01565, Pf02913" 52815 ENSMUSG00000031958.16 Ldhd 8 Pyruvate metabolism 0 High Q922B2 "Aspartate--tRNA ligase, cytoplasmic OS=Mus musculus OX=10090 GN=Dars1 PE=1 SV=2" 0 37.002 25 10 19 10 501 57.1 6.49 95623.64941 120980.665 35943.89844 5 5 3 metabolic process cytoplasm;cytosol;membrane catalytic activity;nucleotide binding;RNA binding "Pf00152, Pf01336" 226414 ENSMUSG00000026356.15 Dars 1 Aminoacyl-tRNA biosynthesis 0 High E9Q1W3 Nebulin OS=Mus musculus OX=10090 GN=Neb PE=1 SV=1 0.004 2.773 0 1 18 1 7152 828.1 9.07 1 1 10015573.88 8307841.563 1430491.813 2562255.688 2 2 2 2 cell organization and biogenesis;regulation of biological process protein binding "Pf00880, Pf14604" 17996 ENSMUSG00000026950.17 Neb 2 Striated Muscle Contraction 0 High Q91VC3 Eukaryotic initiation factor 4A-III OS=Mus musculus OX=10090 GN=Eif4a3 PE=1 SV=3 0 18.05 12 4 18 3 411 46.8 6.73 20098.87207 126798.6816 17907.89844 51677.87988 1 2 1 2 metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;membrane;nucleus;spliceosomal complex catalytic activity;nucleotide binding;RNA binding "Pf00270, Pf00271" 192170 ENSMUSG00000025580.15 Eif4a3 11 mRNA 3'-end processing; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Cleavage of Growing Transcript in the Termination Region ; mRNA Splicing - Major Pathway; ISG15 antiviral mechanism; Transport of Mature mRNA derived from an Intron-Containing Transcript; Deadenylation of mRNA mRNA surveillance pathway; Spliceosome; RNA transport 0 High Q7TPV4 Myb-binding protein 1A OS=Mus musculus OX=10090 GN=Mybbp1a PE=1 SV=2 0 25.334 11 10 18 10 1344 151.9 8.95 1488842.827 2377731.391 210164.7031 539079.377 3 2 1 2 cell communication;cell differentiation;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;membrane;nucleus catalytic activity;DNA binding;metal ion binding;protein binding;RNA binding Pf04931 18432 ENSMUSG00000040463.16 Mybbp1a 11 B-WICH complex positively regulates rRNA expression 0 High P11725 "Ornithine carbamoyltransferase, mitochondrial OS=Mus musculus OX=10090 GN=Otc PE=1 SV=1" 0 24.924 36 8 18 8 354 39.7 8.73 13851.14111 4141.57373 23116.12598 2 1 2 cell organization and biogenesis;metabolic process;response to stimulus cytoplasm;membrane;mitochondrion;organelle lumen catalytic activity "Pf00185, Pf02729" 18416 ENSMUSG00000031173.13 Otc X Urea cycle Metabolic pathways; Biosynthesis of amino acids; Arginine biosynthesis 0 High Q6P1J1 Crmp1 protein OS=Mus musculus OX=10090 GN=Crmp1 PE=1 SV=1 0 13.115 7 4 18 2 686 74.2 6.81 2969.809326 1 cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol catalytic activity;protein binding "Pf01979, Pf07969, Pf13147, Pf13594" 12933 ENSMUSG00000029121.15 Crmp1 5 0 High Q3TQC7 Ectonucleoside triphosphate diphosphohydrolase 5 OS=Mus musculus OX=10090 GN=Entpd5 PE=1 SV=1 0 30.524 31 8 18 8 452 49.8 5.47 20635.3457 621011.3154 469913.0029 1 4 7 cell growth;cell proliferation;metabolic process;regulation of biological process endoplasmic reticulum;extracellular;membrane catalytic activity Pf01150 12499 ENSMUSG00000021236.16 Entpd5 12 0 High D3Z1Y1 E3 ubiquitin-protein ligase synoviolin OS=Mus musculus OX=10090 GN=Syvn1 PE=1 SV=1 0 16.726 8 5 18 5 608 66.9 7.08 14407.52441 22144.66992 53471.96289 1 1 2 metabolic process membrane catalytic activity;metal ion binding;protein binding "Pf00097, Pf12678, Pf12861, Pf12906, Pf13445, Pf13639, Pf13920, Pf13923, Pf14634" ENSMUSG00000024807.17 19 Hedgehog ligand biogenesis; ER Quality Control Compartment (ERQC) 0 High P34914 Bifunctional epoxide hydrolase 2 OS=Mus musculus OX=10090 GN=Ephx2 PE=1 SV=2 0 25.009 31 10 18 10 554 62.5 6.19 594878.9004 457860.3828 216273.8848 136818.918 7 5 3 3 defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol catalytic activity;metal ion binding;protein binding "Pf00561, Pf00702, Pf12146, Pf12695, Pf12697, Pf13242, Pf13419" 13850 ENSMUSG00000022040.7 Ephx2 14 Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) Metabolic pathways; Arachidonic acid metabolism; Peroxisome 0 High Q9DCX2 "ATP synthase subunit d, mitochondrial OS=Mus musculus OX=10090 GN=Atp5pd PE=1 SV=3" 0 31.19 58 8 18 8 161 18.7 5.69 109169.9297 90079.4541 123452.25 23285.22217 3 3 1 2 metabolic process;transport cytosol;membrane;mitochondrion catalytic activity;transporter activity Pf05873 71679 ENSMUSG00000034566.10 Atp5h 11 Cristae formation; Formation of ATP by chemiosmotic coupling Metabolic pathways; Huntington's disease; Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High A0A075B5W3 Immunoglobulin heavy variable 1-53 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-53 PE=4 SV=1 0 19.936 34 2 18 1 117 12.8 8.88 2 1 3 1 343870.2422 297542.7344 18215.18066 2 2 2 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000093894.1 AB069917 12 0 High Q61753 D-3-phosphoglycerate dehydrogenase OS=Mus musculus OX=10090 GN=Phgdh PE=1 SV=3 0 17.421 15 6 18 6 533 56.5 6.54 2396.623535 21935.08984 1 1 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process catalytic activity;nucleotide binding "Pf00389, Pf02826" 236539 ENSMUSG00000053398.11 Phgdh 3 Serine biosynthesis "Metabolic pathways; Biosynthesis of amino acids; Glycine, serine and threonine metabolism; Carbon metabolism" 0 High Q9JIK5 Nucleolar RNA helicase 2 OS=Mus musculus OX=10090 GN=Ddx21 PE=1 SV=3 0 18.001 10 7 17 7 851 93.5 9.11 2039.588379 15429.31348 1 1 cell differentiation;metabolic process;response to stimulus cytoplasm;membrane;nucleus catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00270, Pf00271, Pf08152, Pf14617" 56200 ENSMUSG00000020075.8 Ddx21 10 Major pathway of rRNA processing in the nucleolus and cytosol; B-WICH complex positively regulates rRNA expression 0 High Q8C2Q3 RNA-binding protein 14 OS=Mus musculus OX=10090 GN=Rbm14 PE=1 SV=1 0 28.047 18 7 17 7 669 69.4 9.67 104641.7378 46047.77344 24752.41895 3 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus RNA binding "Pf00076, Pf13893, Pf14259" 56275 ENSMUSG00000006456.10 Rbm14 19 RUNX2 regulates bone development 0 High Q5SUT0 RNA-binding protein EWS OS=Mus musculus OX=10090 GN=Ewsr1 PE=1 SV=1 0 15.721 8 4 17 4 618 64.9 9.38 1 1 158714.9644 8039.372803 5719.693848 4100.737793 3 1 1 1 metabolic process;regulation of biological process cytoplasm;membrane;nucleus metal ion binding;protein binding;RNA binding "Pf00076, Pf00641, Pf14259" 14030 ENSMUSG00000009079.16 Ewsr1 11 0 High E9Q557 Desmoplakin OS=Mus musculus OX=10090 GN=Dsp PE=1 SV=1 0 22.942 4 12 17 12 2883 332.7 6.8 11801.92334 198275.2197 9623.398438 3 4 1 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane;nucleus catalytic activity;motor activity;protein binding;RNA binding;structural molecule activity "Pf00038, Pf00681, Pf01576, Pf02463, Pf04111, Pf04156, Pf05483, Pf05557, Pf05622, Pf06637, Pf06705, Pf07888, Pf10174, Pf12128" 109620 ENSMUSG00000054889.9 Dsp 13 Formation of the cornified envelope; Neutrophil degranulation Arrhythmogenic right ventricular cardiomyopathy (ARVC) 0 High E9Q1S3 Protein transport protein SEC23 OS=Mus musculus OX=10090 GN=Sec23a PE=1 SV=1 0 34.472 20 10 17 10 736 82.9 7.46 82057.45654 581170.8306 156178.4375 270336.1519 5 4 1 5 transport cytoplasm;membrane metal ion binding "Pf00626, Pf04810, Pf04811, Pf04815, Pf08033" ENSMUSG00000020986.13 12 0 High Q921I1 Serotransferrin OS=Mus musculus OX=10090 GN=Tf PE=1 SV=1 0 33.012 20 10 17 10 697 76.7 7.18 56728.13818 43369.38477 4 2 cell differentiation;cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cell surface;endosome;extracellular;membrane metal ion binding;protein binding;transporter activity "Pf00405, Pf12974" 22041 ENSMUSG00000032554.15 Trf 9 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Platelet degranulation ; Cargo recognition for clathrin-mediated endocytosis; Transferrin endocytosis and recycling Mineral absorption; HIF-1 signaling pathway 0 High P47955 60S acidic ribosomal protein P1 OS=Mus musculus OX=10090 GN=Rplp1 PE=1 SV=1 0 16.345 81 3 17 3 114 11.5 4.32 1 1 478086.793 344714.0674 65214.10547 146159.7607 3 3 2 2 Met-loss+Acetyl [N-Term] metabolic process;regulation of biological process ribosome enzyme regulator activity;structural molecule activity Pf00428 56040 ENSMUSG00000007892.8 Rplp1 9 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q8R081 Heterogeneous nuclear ribonucleoprotein L OS=Mus musculus OX=10090 GN=Hnrnpl PE=1 SV=2 0 19.261 14 5 17 5 586 63.9 8.1 205796.6416 378994.625 91119.36816 5 5 3 cell communication;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;nucleus DNA binding;protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 15388 ENSMUSG00000015165.16 Hnrnpl 7 mRNA Splicing - Major Pathway 0 High Q3U0V1 Far upstream element-binding protein 2 OS=Mus musculus OX=10090 GN=Khsrp PE=1 SV=2 0 21.002 9 5 17 5 748 76.7 7.33 24404.9375 6225.615234 1 1 metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;membrane;nucleus DNA binding;RNA binding "Pf00013, Pf07650, Pf09005, Pf13014" 16549 ENSMUSG00000007670.9 Khsrp 17 KSRP (KHSRP) binds and destabilizes mRNA 0 High P06339 "H-2 class I histocompatibility antigen, D-37 alpha chain OS=Mus musculus OX=10090 GN=H2-T23 PE=1 SV=1" 0 28.729 27 10 17 7 357 40.8 6.35 13514.62427 39078.75781 29054.61401 2 1 2 defense response;regulation of biological process;response to stimulus cell surface;membrane protein binding "Pf00129, Pf07654" 15040 ENSMUSG00000067212.8 H2-T23 17 Endocytosis; Herpes simplex infection; Allograft rejection; Epstein-Barr virus infection; Cell adhesion molecules (CAMs); HTLV-I infection; Phagosome; Graft-versus-host disease; Viral myocarditis; Antigen processing and presentation; Type I diabetes mellitus; Natural killer cell mediated cytotoxicity; Autoimmune thyroid disease; Viral carcinogenesis 1 High P43275 Histone H1.1 OS=Mus musculus OX=10090 GN=H1-1 PE=1 SV=2 0 31.638 30 5 17 3 213 21.8 10.93 1 1 61492.39404 46370.85059 55043.71143 2 2 2 Met-loss+Acetyl [N-Term] cell organization and biogenesis;regulation of biological process cell surface;chromosome;nucleus DNA binding;protein binding Pf00538 80838 ENSMUSG00000049539.2 Hist1h1a 13 0 High Q61701 ELAV-like protein 4 OS=Mus musculus OX=10090 GN=Elavl4 PE=1 SV=1 0 14.442 14 5 17 2 385 42.3 9.38 14779.92676 1 cell differentiation;cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;nucleus;ribosome RNA binding "Pf00076, Pf13893, Pf14259" 15572 ENSMUSG00000028546.17 Elavl4 4 3 High Q8R0X7 Sphingosine-1-phosphate lyase 1 OS=Mus musculus OX=10090 GN=Sgpl1 PE=1 SV=1 0 15.561 13 5 17 5 568 63.6 9.1 1270967.614 1298042.462 260361.4219 590076.6133 3 3 1 5 cell death;cell differentiation;cellular component movement;metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;membrane catalytic activity "Pf00155, Pf00266, Pf00282, Pf01212, Pf05889" 20397 ENSMUSG00000020097.14 Sgpl1 10 Sphingolipid de novo biosynthesis Metabolic pathways; Sphingolipid signaling pathway; Sphingolipid metabolism 0 High Q8BWQ1 UDP-glucuronosyltransferase 2A3 OS=Mus musculus OX=10090 GN=Ugt2a3 PE=1 SV=1 0 30.111 23 9 17 8 534 61.1 7.93 58832.21289 15189.37695 17901.31494 3 1 2 metabolic process membrane catalytic activity "Pf00201, Pf04101" 72094 ENSMUSG00000035780.2 Ugt2a3 5 Steroid hormone biosynthesis; Drug metabolism - cytochrome P450; Retinol metabolism; Metabolic pathways; Drug metabolism - other enzymes; Ascorbate and aldarate metabolism; Chemical carcinogenesis; Porphyrin and chlorophyll metabolism; Pentose and glucuronate interconversions; Metabolism of xenobiotics by cytochrome P450 1 High G3UW94 Splicing factor U2AF 35 kDa subunit OS=Mus musculus OX=10090 GN=U2af1 PE=1 SV=1 0 12.651 15 4 16 4 239 27.8 8.68 43821.95898 65338.11914 91705.84521 129785.5503 2 2 2 2 Met-loss+Acetyl [N-Term] metabolic process nucleus;spliceosomal complex metal ion binding;protein binding;RNA binding "Pf00076, Pf00642, Pf13893" 108121 ENSMUSG00000061613.12 U2af1 17 Spliceosome 0 High Q9CQF3 Cleavage and polyadenylation specificity factor subunit 5 OS=Mus musculus OX=10090 GN=Nudt21 PE=1 SV=1 0 17.271 36 5 16 5 227 26.2 8.82 13055.03711 21458.11523 30359.06836 1 1 2 cell organization and biogenesis;metabolic process nucleus catalytic activity;protein binding;RNA binding Pf13869 68219 ENSMUSG00000031754.10 Nudt21 8 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Processing of Intronless Pre-mRNAs; Cleavage of Growing Transcript in the Termination Region mRNA surveillance pathway 0 High Q9CPX4 Ferritin OS=Mus musculus OX=10090 GN=Ftl1 PE=1 SV=1 0 23.737 49 7 16 7 183 20.8 6 48242.41284 103916.6563 171821.0469 36611.50049 4 3 1 3 cellular homeostasis;transport cytoplasm;membrane;vacuole metal ion binding;protein binding Pf00210 14325; 100862446; 634386 ENSMUSG00000062382.7; ENSMUSG00000050708.16 Ftl1; LOC100862446; Gm10116; Ftl1-ps1 7; 4; 13 Neutrophil degranulation; Golgi Associated Vesicle Biogenesis; Iron uptake and transport Mineral absorption 0 High O09173 "Homogentisate 1,2-dioxygenase OS=Mus musculus OX=10090 GN=Hgd PE=1 SV=2" 0 19.919 21 6 16 6 445 49.9 7.24 103842.4888 78287.71875 22072.39746 3 1 2 metabolic process catalytic activity;metal ion binding;protein binding Pf04209 15233 ENSMUSG00000022821.13 Hgd 16 Phenylalanine and tyrosine catabolism Metabolic pathways; Tyrosine metabolism 0 High A0A3B2W3I1 "Vomeronasal 2, receptor 3 OS=Mus musculus OX=10090 GN=Vmn2r3 PE=4 SV=1" 0 29.122 17 4 16 4 470 54 7.91 146530.2891 110513.1797 86276.59375 385538.9688 2 1 1 1 0 High P35550 rRNA 2'-O-methyltransferase fibrillarin OS=Mus musculus OX=10090 GN=Fbl PE=1 SV=2 0 19.877 21 5 16 5 327 34.3 10.24 20345.63867 64787.28308 10868.547 1 3 2 cell differentiation;cell organization and biogenesis;metabolic process chromosome;membrane;nucleus catalytic activity;protein binding;RNA binding "Pf01135, Pf01269, Pf13847" 14113; 102643269 ENSMUSG00000046865.7 LOC100044829; Fbl; LOC102643269 7; 3 Major pathway of rRNA processing in the nucleolus and cytosol Ribosome biogenesis in eukaryotes 0 High P62843 40S ribosomal protein S15 OS=Mus musculus OX=10090 GN=Rps15 PE=1 SV=2 0 12.626 30 3 16 3 145 17 10.39 98080.58398 48637.13672 16868.64063 5378.896484 3 1 1 1 cell differentiation;cell organization and biogenesis;metabolic process;transport membrane;ribosome protein binding;RNA binding;structural molecule activity Pf00203 20054 ENSMUSG00000063457.14 Rps15 10 Ribosome 0 High A0A494BBA8 40S ribosomal protein S30 OS=Mus musculus OX=10090 GN=Fau PE=1 SV=1 0.003 3.736 10 1 16 1 98 10.9 11.56 29898.14648 58799.24609 23344.25391 1 1 1 0 High A0A075B666 Immunoglobulin kappa chain variable 13-85 (Fragment) OS=Mus musculus OX=10090 GN=Igkv13-85 PE=4 SV=5 0 15.533 32 2 16 1 115 12.7 8.29 1 1 2 1 179103.9805 7001.756836 12780.26221 1 1 1 response to stimulus "Pf00047, Pf07686" 434036 ENSMUSG00000079543.3 Igkv13-85 6 0 High Q6P5B5 Fragile X mental retardation syndrome-related protein 2 OS=Mus musculus OX=10090 GN=Fxr2 PE=1 SV=1 0 14.197 11 6 16 3 674 74.2 6.23 1 1 35479.94727 579933.3359 226514.9512 2 4 4 regulation of biological process cytoplasm;cytosol;membrane;nucleus protein binding;RNA binding "Pf00013, Pf05641, Pf12235, Pf13014" 23879 ENSMUSG00000018765.5 Fxr2 11 RNA transport 1 High P83093 Stromal interaction molecule 2 OS=Mus musculus OX=10090 GN=Stim2 PE=1 SV=2 0 28.191 22 10 16 10 746 83.9 6.79 151480.5288 39085.90991 82797.58398 237352.874 4 3 2 6 cellular homeostasis;regulation of biological process;transport endoplasmic reticulum;membrane metal ion binding;protein binding;transporter activity "Pf00536, Pf07647, Pf13868" 116873 ENSMUSG00000039156.19 Stim2 5 Calcium signaling pathway 0 High P62082 40S ribosomal protein S7 OS=Mus musculus OX=10090 GN=Rps7 PE=2 SV=1 0 12.362 21 3 16 3 194 22.1 10.1 3502.313477 65448.53125 80674.10352 1 1 2 Acetyl [N-Term] cell differentiation;metabolic process;regulation of biological process cytoplasm;cytoskeleton;membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity Pf01251 20115 ENSMUSG00000061477.3 Rps7 12 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High A0A0B4J1H6 Immunoglobulin kappa chain variable 2-137 (Fragment) OS=Mus musculus OX=10090 GN=Igkv2-137 PE=4 SV=1 0 8.737 20 2 16 2 120 13.1 7.24 2 1 4 2 991508 1836623.5 132593.8516 214920.0313 2 2 2 2 response to stimulus "Pf00047, Pf07686" 692187 ENSMUSG00000076501.2 Igkv2-137 6 0 High P11370 Retrovirus-related Env polyprotein from Fv-4 locus OS=Mus musculus OX=10090 GN=Fv4 PE=1 SV=2 0 22.876 8 4 16 2 679 74.4 7.81 45446.53516 1 structural molecule activity Pf00429 14352 Fv4 12 0 High O08749 "Dihydrolipoyl dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Dld PE=1 SV=2" 0 30.74 25 8 16 8 509 54.2 7.9 1 1 447494.0879 81226.75195 25037.3125 95607.58545 7 3 1 5 cellular homeostasis;metabolic process;regulation of biological process mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf00070, Pf00890, Pf01134, Pf01946, Pf02852, Pf03486, Pf07992, Pf12831, Pf13450" 13382 ENSMUSG00000020664.10 Dld 12 Glycine degradation; Signaling by Retinoic Acid; Citric acid cycle (TCA cycle); Lysine catabolism; Regulation of pyruvate dehydrogenase (PDH) complex; Branched-chain amino acid catabolism "Pyruvate metabolism; Citrate cycle (TCA cycle); Valine, leucine and isoleucine degradation; Metabolic pathways; Glycine, serine and threonine metabolism; Glycolysis / Gluconeogenesis; Propanoate metabolism; Carbon metabolism; Glyoxylate and dicarboxylate metabolism" 0 High O70503 Very-long-chain 3-oxoacyl-CoA reductase OS=Mus musculus OX=10090 GN=Hsd17b12 PE=1 SV=1 0 33.706 25 6 16 6 312 34.7 9.52 129074.4209 88378.32031 563637.8164 3 1 5 cell organization and biogenesis;metabolic process;regulation of biological process endoplasmic reticulum;membrane catalytic activity;protein binding "Pf00106, Pf02719, Pf08659, Pf13460" 56348 ENSMUSG00000027195.10 Hsd17b12 2 Synthesis of very long-chain fatty acyl-CoAs Fatty acid metabolism; Steroid hormone biosynthesis; Metabolic pathways; Fatty acid elongation; Biosynthesis of unsaturated fatty acids 0 High A0A3B2WBH9 Tight junction protein ZO-2 OS=Mus musculus OX=10090 GN=Tjp2 PE=1 SV=1 0 26.541 9 8 16 7 1165 131 6.79 72387.52295 122849.4424 2 2 1 High A2ACJ2 Fanconi anemia core complex-associated protein 100 OS=Mus musculus OX=10090 GN=Faap100 PE=2 SV=1 0 22.339 18 9 16 9 879 94.2 5.36 28028.47656 72057.41309 13956.42285 46499.11133 1 3 1 2 metabolic process;response to stimulus cytoskeleton;cytosol;nucleus DNA binding;protein binding Pf15146 71885 ENSMUSG00000025384.15 2310003H01Rik; Faap100 11 Fanconi Anemia Pathway Fanconi anemia pathway 0 High P47962 60S ribosomal protein L5 OS=Mus musculus OX=10090 GN=Rpl5 PE=1 SV=3 0 25.233 21 6 16 6 297 34.4 9.77 27287.07275 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity "Pf00861, Pf14204" 100503670 ENSMUSG00000058558.12 Rpl5 5 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q9CZ42 ATP-dependent (S)-NAD(P)H-hydrate dehydratase OS=Mus musculus OX=10090 GN=Naxd PE=1 SV=1 0 22.163 38 9 16 9 343 36.7 7.77 9 13 225135.332 3285827.352 55363.7605 2 7 5 cytosol;endoplasmic reticulum;mitochondrion catalytic activity;nucleotide binding Pf01256 69225 Carkd; Naxd 8 0 High Q8BKZ9 "Pyruvate dehydrogenase protein X component, mitochondrial OS=Mus musculus OX=10090 GN=Pdhx PE=1 SV=1" 0 25.843 20 9 15 9 501 54 7.75 8 10 4644837.234 383704.5156 96018.73047 511768.0742 8 5 2 6 metabolic process mitochondrion;organelle lumen catalytic activity "Pf00198, Pf00364, Pf02817" 27402 ENSMUSG00000010914.10 Pdhx 2 Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Glyoxylate metabolism and glycine degradation Metabolic pathways 0 High P01724 Ig lambda-1 chain V regions MOPC 104E/RPC20/J558/S104 OS=Mus musculus OX=10090 PE=1 SV=1 0 12.516 33 2 15 2 129 13.5 7.28 2 4 4744448.723 1439710.672 203859.3125 126593.1406 3 2 1 1 response to stimulus Pf07686 16142 Iglv1 16 0 High F6R6F1 RalBP1-associated Eps domain-containing protein 1 (Fragment) OS=Mus musculus OX=10090 GN=Reps1 PE=1 SV=1 0 22.576 10 6 15 5 755 81.9 5.91 transport metal ion binding;protein binding "Pf12763, Pf13499" ENSMUSG00000019854.17 10 1 High Q62093 Serine/arginine-rich splicing factor 2 OS=Mus musculus OX=10090 GN=Srsf2 PE=1 SV=4 0 16.733 22 4 15 4 221 25.5 11.85 1 1 113937.6836 540202.2891 41677.60938 104045.9141 2 2 1 3 Met-loss+Acetyl [N-Term] metabolic process;regulation of biological process;response to stimulus cytosol;nucleus;spliceosomal complex protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 20382 ENSMUSG00000034120.18 Srsf2 11 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript Herpes simplex infection; Spliceosome 0 High Q6P5B0 RRP12-like protein OS=Mus musculus OX=10090 GN=Rrp12 PE=1 SV=1 0 22.574 12 11 15 11 1295 143 8.91 28731.02051 29511.23242 98973.08472 170115.6592 2 2 2 3 membrane;nucleus RNA binding Pf08161 107094 ENSMUSG00000035049.3 Rrp12 19 0 High Q9QXM0 Monoacylglycerol lipase ABHD2 OS=Mus musculus OX=10090 GN=Abhd2 PE=1 SV=1 0 25.492 31 9 15 9 425 48.3 6.7 9474.683594 8920.786133 1 1 Acetyl [N-Term] metabolic process;regulation of biological process;response to stimulus;transport membrane catalytic activity;receptor activity;signal transducer activity "Pf00561, Pf12697" 54608 ENSMUSG00000039202.12 Abhd2 7 0 High Q02248 Catenin beta-1 OS=Mus musculus OX=10090 GN=Ctnnb1 PE=1 SV=1 0 23.239 9 5 15 4 781 85.4 5.86 44107.97559 19475.65088 2 2 cell communication;cell differentiation;cell growth;cell organization and biogenesis;cell proliferation;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;membrane;nucleus DNA binding;protein binding;signal transducer activity Pf00514 12387 ENSMUSG00000006932.17 Ctnnb1 9 Beta-catenin phosphorylation cascade; Deactivation of the beta-catenin transactivating complex; VEGFR2 mediated vascular permeability; Ca2+ pathway; Adherens junctions interactions; Formation of the beta-catenin:TCF transactivating complex; RHO GTPases activate IQGAPs; Disassembly of the destruction complex and recruitment of AXIN to the membrane; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production; Apoptotic cleavage of cell adhesion proteins; CDO in myogenesis; RUNX3 regulates WNT signaling Leukocyte transendothelial migration; Wnt signaling pathway; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Focal adhesion; Endometrial cancer; Basal cell carcinoma; Hippo signaling pathway; Breast cancer; Signaling pathways regulating pluripotency of stem cells; Melanogenesis; HTLV-I infection; Adherens junction; Proteoglycans in cancer; Thyroid hormone signaling pathway; Rap1 signaling pathway; Pathways in cancer; Thyroid cancer; Tight junction; Colorectal cancer; Prostate cancer; Bacterial invasion of epithelial cells 0 High A0A075B5Y1 Immunoglobulin heavy variable V1-74 OS=Mus musculus OX=10090 GN=Ighv1-74 PE=4 SV=1 0 13.017 23 2 15 1 116 12.9 8.88 2 1 3 1 426656.917 38783.02344 38007.50391 2 1 1 Pf07686 ENSMUSG00000094124.5 12 0 High A0A075B5Q2 Immunoglobulin heavy variable 5-9 (Fragment) OS=Mus musculus OX=10090 GN=Ighv5-9 PE=4 SV=1 0 9.662 19 2 15 1 117 12.8 8.92 2 1 4 2 545247.3125 453578.375 26361.4082 2 2 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000095285.2 LOC674130 12 0 High Q9EP71 Ankycorbin OS=Mus musculus OX=10090 GN=Rai14 PE=1 SV=1 0 35.795 14 10 15 10 979 108.8 6.27 13905.50391 7432.850586 3612.130127 1 1 1 cell differentiation;cell organization and biogenesis;transport cytoplasm;cytoskeleton;cytosol;membrane;mitochondrion;nucleus catalytic activity;motor activity;protein binding "Pf00023, Pf00529, Pf01576, Pf03961, Pf05667, Pf05701, Pf12128, Pf12796, Pf13166, Pf13514, Pf13606, Pf13637, Pf13857, Pf14817" 75646 ENSMUSG00000022246.13 Rai14 15 0 High Q9Z1E4 "Glycogen [starch] synthase, muscle OS=Mus musculus OX=10090 GN=Gys1 PE=1 SV=2" 0 9.737 10 5 15 4 738 83.9 6.11 1 3 1 3 590188.9248 623252.6289 780264.1055 235723.9785 4 4 4 4 metabolic process cytoplasm;membrane catalytic activity;protein binding "Pf00534, Pf05693, Pf13579" 14936 ENSMUSG00000003865.16 Gys1 7 Glycogen synthesis Insulin signaling pathway; Metabolic pathways; Insulin resistance; Starch and sucrose metabolism; PI3K-Akt signaling pathway; AMPK signaling pathway; Glucagon signaling pathway 0 High Q9QXE0 2-hydroxyacyl-CoA lyase 1 OS=Mus musculus OX=10090 GN=Hacl1 PE=1 SV=2 0 17.001 17 7 15 7 581 63.6 6.27 407075.0078 14303.32715 29971.67188 1 1 2 cell organization and biogenesis;metabolic process catalytic activity;metal ion binding;protein binding "Pf00205, Pf02775, Pf02776" 56794 ENSMUSG00000021884.17 Hacl1 14 Alpha-oxidation of phytanate Peroxisome 0 High Q02788 Collagen alpha-2(VI) chain OS=Mus musculus OX=10090 GN=Col6a2 PE=1 SV=3 0 21.202 7 5 15 5 1034 110.3 6.42 3 1 3 1 519706.1738 251751.5879 66009.44531 48276.15332 5 3 2 1 cell organization and biogenesis;response to stimulus extracellular;membrane "Pf00092, Pf01391, Pf13519" 12834 ENSMUSG00000020241.13 Col6a2 10 ECM proteoglycans; Collagen chain trimerization; Integrin cell surface interactions; NCAM1 interactions; Collagen degradation; Signaling by PDGF; Assembly of collagen fibrils and other multimeric structures Focal adhesion; Protein digestion and absorption; ECM-receptor interaction; PI3K-Akt signaling pathway 0 High P97496 SWI/SNF complex subunit SMARCC1 OS=Mus musculus OX=10090 GN=Smarcc1 PE=1 SV=2 0 10.096 4 4 15 2 1104 122.8 5.73 37457.16797 4222.683594 2 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus chromosome;cytoplasm;nucleus DNA binding;protein binding Pf04433 20588 ENSMUSG00000032481.16 Smarcc1 9 RMTs methylate histone arginines; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 2 High P14211 Calreticulin OS=Mus musculus OX=10090 GN=Calr PE=1 SV=1 0 16.419 18 5 15 5 416 48 4.49 7111.32666 135865.9492 1 3 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;cytosol;endoplasmic reticulum;extracellular;Golgi;membrane;nucleus;organelle lumen metal ion binding;protein binding;RNA binding Pf00262 12317 ENSMUSG00000003814.8 Calr 8 "Calnexin/calreticulin cycle; Scavenging by Class A Receptors; ER-Phagosome pathway; Antigen Presentation: Folding, assembly and peptide loading of class I MHC" Chagas disease (American trypanosomiasis); HTLV-I infection; Phagosome; Antigen processing and presentation; Protein processing in endoplasmic reticulum 0 High Q91XD4 Formimidoyltransferase-cyclodeaminase OS=Mus musculus OX=10090 GN=Ftcd PE=1 SV=1 0 29.306 21 7 15 7 541 58.9 6.11 224478.3203 29611.59375 22669.33008 1 1 2 cell organization and biogenesis;metabolic process cytoplasm;cytoskeleton;cytosol;endoplasmic reticulum;Golgi;membrane catalytic activity;protein binding "Pf02971, Pf04961, Pf07837" 14317 ENSMUSG00000001155.13 Ftcd 10 Histidine catabolism Histidine metabolism; Metabolic pathways; One carbon pool by folate 0 High P63276 40S ribosomal protein S17 OS=Mus musculus OX=10090 GN=Rps17 PE=1 SV=2 0 9.014 48 4 15 4 135 15.5 9.85 35816.95068 238079.7622 552299.3984 266678.5337 2 3 2 3 cell organization and biogenesis;metabolic process membrane;ribosome RNA binding;structural molecule activity Pf00833 20068 ENSMUSG00000061787.15 Rps17 7 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High A0A0A6YXQ0 Immunoglobulin heavy variable 8-8 (Fragment) OS=Mus musculus OX=10090 GN=Ighv8-8 PE=4 SV=1 0 12.333 13 1 14 1 119 13.2 8.84 1 1 2 1 338193.6875 627359.75 13124.0459 71435.35156 1 1 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000104452.1 12 Regulation of Complement cascade; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Cell surface interactions at the vascular wall; FCERI mediated NF-kB activation; Role of LAT2/NTAL/LAB on calcium mobilization; Role of phospholipids in phagocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR activation; Classical antibody-mediated complement activation; FCERI mediated Ca+2 mobilization; FCERI mediated MAPK activation; CD22 mediated BCR regulation; Scavenging of heme from plasma 0 High A0A338P6T4 AP-2 complex subunit mu (Fragment) OS=Mus musculus OX=10090 GN=Ap2m1 PE=1 SV=1 0 21.464 58 4 14 2 119 13.7 5.2 0 High P08226 Apolipoprotein E OS=Mus musculus OX=10090 GN=Apoe PE=1 SV=2 0 30.366 26 8 14 8 311 35.8 5.68 11830.20972 3693.425537 2 1 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;cytosol;endoplasmic reticulum;endosome;extracellular;Golgi;membrane;nucleus;vacuole antioxidant activity;catalytic activity;enzyme regulator activity;metal ion binding;protein binding;transporter activity "Pf01442, Pf02720" 11816 ENSMUSG00000002985.16 Apoe 7 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Chylomicron clearance; Post-translational protein phosphorylation; Scavenging by Class A Receptors; Chylomicron assembly; Signaling by GPCR; Retinoid metabolism and transport; HDL remodeling; Chylomicron remodeling Alzheimer's disease 0 High A0A140T8T4 "Ribosomal protein L9, pseudogene 6 OS=Mus musculus OX=10090 GN=Rpl9-ps6 PE=4 SV=1" 0 12.555 11 3 14 3 192 21.8 9.88 32762.72266 3 metabolic process ribosome RNA binding;structural molecule activity Pf00347 100042823 ENSMUSG00000062456.3 Rpl9-ps6 19 0 High Q61191 Host cell factor 1 OS=Mus musculus OX=10090 GN=Hcfc1 PE=1 SV=2 0 18.528 6 8 14 8 2045 210.3 7.18 51203837.13 81086837.94 20307710 42288739.14 2 4 2 3 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus catalytic activity;protein binding "Pf01344, Pf13415, Pf13418, Pf13854, Pf13964" 15161 ENSMUSG00000031386.14 Hcfc1 X HATs acetylate histones; UCH proteinases Herpes simplex infection 0 High E9Q0Y4 Signal-induced proliferation-associated protein 1 OS=Mus musculus OX=10090 GN=Sipa1 PE=1 SV=1 0 21.663 18 11 14 11 1038 112.2 6.44 210657.9121 27304.78125 17419.53955 20568.7356 3 1 2 3 cell communication;regulation of biological process;response to stimulus nucleus enzyme regulator activity;protein binding "Pf00595, Pf02145, Pf13949" 20469 ENSMUSG00000056917.12 Sipa1 19 Rap1 signalling Leukocyte transendothelial migration; Rap1 signaling pathway 0 High Q9Z0R6 Intersectin-2 OS=Mus musculus OX=10090 GN=Itsn2 PE=1 SV=2 0 28.855 6 8 14 8 1659 188.8 8.13 8729.140381 24614.2002 2 2 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton enzyme regulator activity;metal ion binding;nucleotide binding;protein binding "Pf00018, Pf00168, Pf00169, Pf00621, Pf01025, Pf02463, Pf03961, Pf03962, Pf04111, Pf04156, Pf05483, Pf06156, Pf06160, Pf06818, Pf07653, Pf07888, Pf07926, Pf09731, Pf10174, Pf10186, Pf12763, Pf13514, Pf14604" 20403 Itsn2 12 0 High Q3UZ09 Complement C1r subcomponent-like protein OS=Mus musculus OX=10090 GN=C1rl PE=1 SV=1 0 14.11 9 3 14 2 482 53.4 6.47 1 1 21252.2832 1 defense response;metabolic process;regulation of biological process;response to stimulus extracellular catalytic activity "Pf00089, Pf00431" 232371 ENSMUSG00000038527.9 C1rl 6 0 High Q80XR6 Heterogeneous nuclear ribonucleoprotein A/B OS=Mus musculus OX=10090 GN=Hnrnpab PE=1 SV=1 0 9.111 8 2 14 1 311 33.8 5.83 1 1 40350.05078 100358.0703 32303.19141 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;nucleus DNA binding;protein binding;RNA binding "Pf00076, Pf08143, Pf13893, Pf14259" 15384 ENSMUSG00000020358.17 Hnrnpab 11 0 High A0A075B5X3 Immunoglobulin heavy variable 1-64 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-64 PE=4 SV=1 0 18.686 34 2 14 1 117 12.9 9.06 1 1 2 1 302433.3438 195332.248 42674.71582 1 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000094088.2 12 0 High Q3UPL0 Protein transport protein Sec31A OS=Mus musculus OX=10090 GN=Sec31a PE=1 SV=2 0 23.629 11 11 14 11 1230 133.5 6.76 115458.9585 18298.4165 5 3 cell organization and biogenesis;response to stimulus;transport cytoplasm;cytosol;endoplasmic reticulum;endosome;membrane protein binding "Pf03154, Pf12931" 69162 ENSMUSG00000035325.16 Sec31a 5 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC; COPII (Coat Protein 2) Mediated Vesicle Transport; MHC class II antigen presentation" Protein processing in endoplasmic reticulum 0 High Q7TNC4 Putative RNA-binding protein Luc7-like 2 OS=Mus musculus OX=10090 GN=Luc7l2 PE=1 SV=1 0 30.777 18 6 14 4 392 46.6 10.1 21618.92383 96494.73047 1 2 cell organization and biogenesis nucleus;spliceosomal complex protein binding;RNA binding Pf03194 192196 ENSMUSG00000029823.16 Luc7l2 6 2 High A0A0G2JFS5 Immunoglobulin heavy variable 1-69 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-69 PE=4 SV=1 0 12.25 34 2 14 1 117 12.9 7.87 2 2 3 2 1154412.375 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000094502.5 12 0 High P43276 Histone H1.5 OS=Mus musculus OX=10090 GN=H1-5 PE=1 SV=2 0 9.977 18 3 14 3 223 22.6 10.92 38290.64697 83437.33203 27930.89111 3 2 2 Met-loss+Acetyl [N-Term] cell organization and biogenesis chromosome;nucleus DNA binding;protein binding Pf00538 56702 ENSMUSG00000058773.2 Hist1h1b 13 0 High Q78JT3 "3-hydroxyanthranilate 3,4-dioxygenase OS=Mus musculus OX=10090 GN=Haao PE=1 SV=1" 0 17.1 26 6 14 6 286 32.8 6.54 57368.17285 31217.23242 3 1 cellular homeostasis;metabolic process;response to stimulus cytoplasm;cytosol;membrane catalytic activity;metal ion binding "Pf06052, Pf07883" 107766 ENSMUSG00000000673.8 Haao 17 Tryptophan catabolism Tryptophan metabolism; Metabolic pathways 0 High P62900 60S ribosomal protein L31 OS=Mus musculus OX=10090 GN=Rpl31 PE=1 SV=1 0 8.926 39 5 14 5 125 14.5 10.54 77326.55859 46463.71875 40031.57422 2 1 1 metabolic process membrane;ribosome protein binding;RNA binding;structural molecule activity Pf01198 114641 ENSMUSG00000073702.11 Rpl31 1 Ribosome 0 High A0A571BEF4 SH3 domain-containing protein 19 OS=Mus musculus OX=10090 GN=Sh3d19 PE=1 SV=1 0 25.432 12 8 14 8 1065 116.3 8.43 1697.775757 1 0 High Q8K154 UDP-glucuronosyltransferase OS=Mus musculus OX=10090 GN=Ugt2b34 PE=1 SV=1 0 26.224 23 8 14 7 532 60.8 7.88 262055.5859 46450.83203 208032.75 112378.2061 3 2 1 2 metabolic process membrane catalytic activity "Pf00201, Pf04101" 100727 ENSMUSG00000029260.15 Ugt2b34 5 Steroid hormone biosynthesis; Drug metabolism - cytochrome P450; Retinol metabolism; Metabolic pathways; Drug metabolism - other enzymes; Ascorbate and aldarate metabolism; Chemical carcinogenesis; Porphyrin and chlorophyll metabolism; Pentose and glucuronate interconversions; Metabolism of xenobiotics by cytochrome P450 0 High Q8C6B0 Methyltransferase-like 7A1 OS=Mus musculus OX=10090 GN=Mettl7a1 PE=1 SV=1 0 14.983 28 5 14 5 244 28.1 8.31 303669.9321 495736.749 188546.2969 131733.1113 3 3 1 2 metabolic process membrane catalytic activity "Pf01209, Pf01739, Pf05148, Pf08241, Pf08242, Pf12847, Pf13489, Pf13649, Pf13659, Pf13847" 70152 ENSMUSG00000054619.6 Mettl7a1 15 Neutrophil degranulation 0 High Q06890 Clusterin OS=Mus musculus OX=10090 GN=Clu PE=1 SV=1 0 19.632 21 7 13 7 448 51.6 5.67 47713.2998 67160.39355 5350.200684 3 2 1 cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;cytosol;endoplasmic reticulum;extracellular;membrane;mitochondrion;nucleus catalytic activity;protein binding Pf01093 12759 ENSMUSG00000022037.14 Clu 14 Regulation of Complement cascade; Platelet degranulation ; Terminal pathway of complement; Antimicrobial peptides Complement and coagulation cascades 0 High Q99MR3 Solute carrier family 12 member 9 OS=Mus musculus OX=10090 GN=Slc12a9 PE=1 SV=2 0 17.317 14 7 13 7 914 96.3 7.02 39832.40625 1 transport membrane transporter activity "Pf00324, Pf13520" 83704 ENSMUSG00000037344.13 Slc12a9 5 0 High Q9CQE8 "RNA transcription, translation and transport factor protein OS=Mus musculus OX=10090 GN=RTRAF PE=1 SV=1" 0 12.529 32 6 13 6 244 28.1 6.89 135243.7612 62456.98438 94528.16113 81517.09961 4 2 2 3 metabolic process;regulation of biological process cytoplasm;cytoskeleton;cytosol;nucleus protein binding;RNA binding Pf10036 68045 ENSMUSG00000021807.5 2700060E02Rik; Rtraf 14 0 High P67871 Casein kinase II subunit beta OS=Mus musculus OX=10090 GN=Csnk2b PE=1 SV=1 0 12.51 40 6 13 6 215 24.9 5.55 5209.420898 182277.5469 117132.4141 103589.25 1 1 2 1 metabolic process;regulation of biological process;response to stimulus chromosome;cytoplasm;membrane;nucleus catalytic activity;enzyme regulator activity;metal ion binding;protein binding Pf01214 13001 ENSMUSG00000024387.13 Csnk2b 17 WNT mediated activation of DVL; Regulation of TP53 Activity through Phosphorylation; Neutrophil degranulation; Synthesis of PC; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Condensation of Prometaphase Chromosomes; Receptor Mediated Mitophagy; Regulation of PTEN stability and activity; Signal transduction by L1; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Herpes simplex infection; Wnt signaling pathway; Epstein-Barr virus infection; Adherens junction; Ribosome biogenesis in eukaryotes; NF-kappa B signaling pathway; Tight junction; Measles 0 High Q9QYI6 DnaJ homolog subfamily B member 9 OS=Mus musculus OX=10090 GN=Dnajb9 PE=1 SV=2 0 31.123 35 7 13 7 222 25.6 8.28 6204.313477 68861.1543 1 3 metabolic process cytoplasm;endoplasmic reticulum;organelle lumen protein binding Pf00226 27362 ENSMUSG00000014905.4 Dnajb9 12 0 High Q91X77 Cytochrome P450 2C50 OS=Mus musculus OX=10090 GN=Cyp2c50 PE=1 SV=2 0 31.651 17 6 13 4 490 55.7 7.88 79498.64063 144250.6563 1 1 metabolic process endoplasmic reticulum;membrane catalytic activity;metal ion binding Pf00067 107141 ENSMUSG00000054827.12 Cyp2c50 19 Steroid hormone biosynthesis; Retinol metabolism; Metabolic pathways; Linoleic acid metabolism; Arachidonic acid metabolism; Chemical carcinogenesis; Serotonergic synapse; Inflammatory mediator regulation of TRP channels 2 High Q9QXX4 Calcium-binding mitochondrial carrier protein Aralar2 OS=Mus musculus OX=10090 GN=Slc25a13 PE=1 SV=1 0 21.271 19 8 13 6 676 74.4 8.6 73215.96826 32741.04578 14529.22339 4 2 2 metabolic process;response to stimulus;transport membrane;mitochondrion metal ion binding;transporter activity "Pf00153, Pf13499" 50799 ENSMUSG00000015112.15 Slc25a13 6 Gluconeogenesis 2 High P61514 60S ribosomal protein L37a OS=Mus musculus OX=10090 GN=Rpl37a PE=1 SV=2 0 14.858 41 3 13 3 92 10.3 10.43 86022.70068 32602.10742 22205.24414 2 1 1 metabolic process nucleus;ribosome metal ion binding;RNA binding;structural molecule activity Pf01780 19981 ENSMUSG00000046330.10 Rpl37a 1 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q9DBG1 "Sterol 26-hydroxylase, mitochondrial OS=Mus musculus OX=10090 GN=Cyp27a1 PE=1 SV=1" 0 19.078 13 5 13 5 533 60.7 9.14 54485.99609 8339.224609 1 1 metabolic process membrane;mitochondrion catalytic activity;metal ion binding Pf00067 104086 ENSMUSG00000026170.6 Cyp27a1 1 Endogenous sterols; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; Synthesis of bile acids and bile salts via 24-hydroxycholesterol; Synthesis of bile acids and bile salts via 27-hydroxycholesterol PPAR signaling pathway; Metabolic pathways; Primary bile acid biosynthesis 0 High G3UWY3 Protein cordon-bleu OS=Mus musculus OX=10090 GN=Cobl PE=1 SV=1 0 18.714 7 6 13 6 1330 143.2 7.39 77749.57422 140396.0352 13366.26855 2 2 1 cell growth;cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton;membrane protein binding Pf09469 12808 ENSMUSG00000020173.17 Cobl 11 0 High P10404 MLV-related proviral Env polyprotein OS=Mus musculus OX=10090 PE=1 SV=3 0 17.225 8 4 13 2 641 69.6 7.96 8462.679688 4297.183105 8347.78418 1 1 1 membrane metal ion binding;structural molecule activity Pf00429 Env 2 High P51655 Glypican-4 OS=Mus musculus OX=10090 GN=Gpc4 PE=1 SV=2 0 32.767 16 6 13 5 557 62.5 6.33 2005.48584 1 extracellular;membrane;nucleus;organelle lumen protein binding Pf01153 14735 ENSMUSG00000031119.4 Gpc4 X HS-GAG degradation; A tetrasaccharide linker sequence is required for GAG synthesis; Signaling by GPCR; Retinoid metabolism and transport; HS-GAG biosynthesis Wnt signaling pathway 1 High A0A075B5W2 Immunoglobulin heavy variable 1-52 OS=Mus musculus OX=10090 GN=Ighv1-52 PE=4 SV=1 0 10.588 34 2 13 1 116 13 7.88 1 1 2 1 456181.8281 205829.4688 1 1 Pf07686 ENSMUSG00000095204.6 12 0 High A0A140T8N8 Immunoglobulin kappa variable 9-123 (Fragment) OS=Mus musculus OX=10090 GN=Igkv9-123 PE=4 SV=2 0 17.842 26 2 13 2 117 12.8 6.54 1 1 479102.3555 72532.72266 12482.42773 2 2 1 "Pf00047, Pf07679, Pf07686" 628144 ENSMUSG00000076512.2 Igkv9-123 6 0 High Q8BSH9 Nucleosome assembly protein 1-like 1 OS=Mus musculus OX=10090 GN=Nap1l1 PE=1 SV=1 0 12.319 12 3 13 2 383 44.6 4.56 cell organization and biogenesis cytoplasm;membrane;nucleus protein binding;RNA binding Pf00956 53605 ENSMUSG00000058799.15 Nap1l1 10 1 High B1AXZ5 ELAV-like protein OS=Mus musculus OX=10090 GN=Elavl2 PE=1 SV=1 0 9.895 10 4 13 1 389 42.6 9.04 RNA binding "Pf00076, Pf13893, Pf14259" 15569 ENSMUSG00000008489.18 Elavl2 4 0 High P26150 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 3 OS=Mus musculus OX=10090 GN=Hsd3b3 PE=1 SV=3 0 23.879 26 8 13 6 373 42 7.97 34862.54395 13416.08105 2 2 Met-loss [N-Term] metabolic process endoplasmic reticulum;membrane;mitochondrion catalytic activity "Pf00106, Pf01073, Pf01370, Pf02719, Pf03435, Pf04321, Pf05368, Pf07993, Pf08659, Pf13460" 15494 ENSMUSG00000062410.14 Hsd3b3 3 Glucocorticoid biosynthesis; Androgen biosynthesis; Mineralocorticoid biosynthesis 2 High A0A1L1SSC7 Tetratricopeptide repeat domain 13 OS=Mus musculus OX=10090 GN=Ttc13 PE=1 SV=1 0 34.348 19 11 13 11 844 95 6.96 95569.38281 141729.9121 116607.5469 68504.56934 2 2 1 4 protein binding "Pf00515, Pf07719, Pf13181, Pf13414, Pf13424, Pf13432, Pf14559" 234875 ENSMUSG00000037300.18 Ttc13 8 0 High Q91YI0 Argininosuccinate lyase OS=Mus musculus OX=10090 GN=Asl PE=1 SV=1 0 19.917 17 7 13 7 464 51.7 6.96 45850.11279 4830.447754 7592.530273 4 1 1 metabolic process;response to stimulus cytoplasm;endoplasmic reticulum;membrane;nucleus catalytic activity;protein binding "Pf00206, Pf14698" 109900 ENSMUSG00000025533.15 Asl 5 "Metabolic pathways; Biosynthesis of amino acids; Alanine, aspartate and glutamate metabolism; Arginine biosynthesis" 0 High Q05421 Cytochrome P450 2E1 OS=Mus musculus OX=10090 GN=Cyp2e1 PE=1 SV=1 0 13.393 9 3 13 3 493 56.8 8.4 11247.72266 1 metabolic process;response to stimulus endoplasmic reticulum;membrane;mitochondrion catalytic activity;metal ion binding;protein binding Pf00067 13106 ENSMUSG00000025479.9 Cyp2e1 7 CYP2E1 reactions Steroid hormone biosynthesis; Drug metabolism - cytochrome P450; Metabolic pathways; Linoleic acid metabolism; Non-alcoholic fatty liver disease (NAFLD); Arachidonic acid metabolism; Chemical carcinogenesis; Metabolism of xenobiotics by cytochrome P450 0 High P56593 Cytochrome P450 2A12 OS=Mus musculus OX=10090 GN=Cyp2a12 PE=1 SV=2 0 18.084 17 6 13 6 492 56.1 9.19 6154.66748 13534.38379 48779.87891 1 1 1 metabolic process endoplasmic reticulum;membrane catalytic activity;metal ion binding Pf00067 13085 ENSMUSG00000060407.6 Cyp2a12 7 Aflatoxin activation and detoxification; Xenobiotics Retinol metabolism; Metabolic pathways 0 High E9QP99 Golgin subfamily A member 3 OS=Mus musculus OX=10090 GN=Golga3 PE=1 SV=1 0 24.11 9 11 13 11 1487 167.2 5.38 203827.4063 213116.5381 21710.55859 98052.27832 7 5 1 3 cell differentiation;development;metabolic process;regulation of biological process cytoplasm;cytosol;Golgi;membrane;nucleus protein binding "Pf02463, Pf04111, Pf04156, Pf05557, Pf07888, Pf09726, Pf10186, Pf12128, Pf13166" 269682 ENSMUSG00000029502.14 Golga3 5 0 High O09165 Calsequestrin-1 OS=Mus musculus OX=10090 GN=Casq1 PE=1 SV=3 0 20.094 15 3 13 3 405 46.3 4.12 1 1 481570.4805 934923.3203 144018.252 45217.70313 2 2 2 1 cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;endoplasmic reticulum;Golgi;membrane;mitochondrion;organelle lumen metal ion binding;protein binding "Pf01216, Pf13848" 12372 ENSMUSG00000007122.11 Casq1 1 Stimuli-sensing channels; Ion homeostasis 0 High Q64458 Cytochrome P450 2C29 OS=Mus musculus OX=10090 GN=Cyp2c29 PE=1 SV=2 0 16.5 20 6 12 4 490 55.7 8.29 87835.94849 10344.85156 2 1 metabolic process endoplasmic reticulum;membrane catalytic activity;metal ion binding Pf00067 13095 ENSMUSG00000003053.17 Cyp2c29 19 Steroid hormone biosynthesis; Retinol metabolism; Metabolic pathways; Linoleic acid metabolism; Arachidonic acid metabolism; Chemical carcinogenesis; Serotonergic synapse; Inflammatory mediator regulation of TRP channels 1 High A0A075B677 Immunoglobulin kappa variable 4-53 OS=Mus musculus OX=10090 GN=Igkv4-53 PE=1 SV=1 0 8.65 19 1 12 1 97 10.4 5.1 1 1 2 2 1879331.75 2670945.75 1 1 ENSMUSG00000095753.2 6 0 High J3QNW9 Kinesin-like protein KIF7 OS=Mus musculus OX=10090 GN=Kif7 PE=1 SV=1 0 8.452 4 4 12 3 1348 151.6 6.57 878884096 595190550 281000138 388734144.8 1 1 1 1 cellular component movement;regulation of biological process cytoplasm;cytoskeleton catalytic activity;motor activity;nucleotide binding;protein binding "Pf00225, Pf09726" 16576 ENSMUSG00000050382.14 Kif7 7 Hedgehog 'on' state; Hedgehog 'off' state Hedgehog signaling pathway 1 High Q3U1J4 DNA damage-binding protein 1 OS=Mus musculus OX=10090 GN=Ddb1 PE=1 SV=2 0 14.682 7 5 12 5 1140 126.8 5.26 19205.17334 103544.2656 40153.20117 30886.54004 2 2 2 2 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus DNA binding;protein binding "Pf03178, Pf10433" 13194 ENSMUSG00000024740.9 Ddb1 19 Dual incision in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; DNA Damage Recognition in GG-NER; Formation of Incision Complex in GG-NER; Neddylation; Formation of TC-NER Pre-Incision Complex; Gap-filling DNA repair synthesis and ligation in TC-NER Ubiquitin mediated proteolysis; Hepatitis B; Nucleotide excision repair; Viral carcinogenesis 0 High A0A0G2JDE1 Immunoglobulin heavy variable V8-12 (Fragment) OS=Mus musculus OX=10090 GN=Ighv8-12 PE=4 SV=1 0 7.595 13 1 12 1 119 13.3 9.17 1 1 2 2 685377.875 919076.5625 186999.9688 1 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000076731.3 12 Regulation of Complement cascade; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Cell surface interactions at the vascular wall; FCERI mediated NF-kB activation; Role of LAT2/NTAL/LAB on calcium mobilization; Role of phospholipids in phagocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR activation; Classical antibody-mediated complement activation; FCERI mediated Ca+2 mobilization; FCERI mediated MAPK activation; CD22 mediated BCR regulation; Scavenging of heme from plasma 0 High D3Z2R5 Selenoprotein N OS=Mus musculus OX=10090 GN=Selenon PE=3 SV=2 0 13.356 19 6 12 6 557 62.5 5.55 73870.76758 25787.85474 31131.11523 203725.1953 2 2 1 2 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;membrane catalytic activity;metal ion binding 74777 ENSMUSG00000050989.9 Sepn1; Selenon 4 0 High H7BX95 Serine/arginine-rich-splicing factor 1 OS=Mus musculus OX=10090 GN=Srsf1 PE=1 SV=1 0 9.784 16 4 12 4 253 28.3 10.08 1 2 85566.79883 445616.666 116171.2695 2 2 2 metabolic process nucleus protein binding;RNA binding "Pf00076, Pf13893, Pf14259" ENSMUSG00000018379.17; ENSMUSG00000098301.6 11; CHR_MG3829_PATCH 0 High P24369 Peptidyl-prolyl cis-trans isomerase B OS=Mus musculus OX=10090 GN=Ppib PE=1 SV=2 0 17.686 33 6 12 6 216 23.7 9.55 1 1 34724.25 365029.3965 65480.88477 2 4 2 metabolic process;regulation of biological process endoplasmic reticulum;membrane;nucleus;organelle lumen catalytic activity;protein binding;RNA binding Pf00160 19035 ENSMUSG00000032383.7 Ppib 9 Collagen biosynthesis and modifying enzymes 0 High A0A5F8MPM8 "Spectrin beta, non-erythrocytic 2 (Fragment) OS=Mus musculus OX=10090 GN=Sptbn2 PE=1 SV=1" 0 12.229 60 4 12 1 110 12.1 7.34 59143.53906 16697.43164 6852.285645 2 2 1 0 High Q62371 Discoidin domain-containing receptor 2 OS=Mus musculus OX=10090 GN=Ddr2 PE=1 SV=2 0 23.907 14 8 12 8 854 96.4 5.49 119863.7175 162581.2002 23974.54858 4 4 3 cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process;response to stimulus cytoskeleton;membrane catalytic activity;nucleotide binding;protein binding;receptor activity;signal transducer activity "Pf00069, Pf00754, Pf07714" 18214 ENSMUSG00000026674.9 Ddr2 1 Non-integrin membrane-ECM interactions 0 High Q3TE00 Mediator of RNA polymerase II transcription subunit 15 OS=Mus musculus OX=10090 GN=Med15 PE=1 SV=1 0 11.835 6 4 12 4 766 83.7 9.36 6267.197021 24370.56494 24003.11523 89950.48828 2 2 1 2 metabolic process;regulation of biological process cytoplasm;nucleus Pf09606 94112 Med15 16 0 High P41317 Mannose-binding protein C OS=Mus musculus OX=10090 GN=Mbl2 PE=1 SV=2 0 17.265 22 4 12 4 244 25.9 5.06 6040.392822 10282.73633 2 1 defense response;metabolic process;regulation of biological process;response to stimulus extracellular metal ion binding;protein binding Pf00059 17195 ENSMUSG00000024863.5 Mbl2 19 Lectin pathway of complement activation Staphylococcus aureus infection; Phagosome; Complement and coagulation cascades 0 High A0A075B5K7 Immunoglobulin kappa chain variable 14-100 OS=Mus musculus OX=10090 GN=Igkv14-100 PE=4 SV=7 0 10.417 14 1 12 1 116 12.6 4.78 1 1 2 3 345988.0938 1791085.125 60883.19727 61693.88477 1 1 1 1 "Pf00047, Pf07679, Pf07686" ENSMUSG00000096515.5 6 0 High A0A2I3BRT4 Epiplakin OS=Mus musculus OX=10090 GN=Eppk1 PE=1 SV=1 0 25.622 6 6 12 5 3458 381.5 5.92 16662.61914 19117.47656 1 1 0 High Q3URQ4 "Family with sequence similarity 8, member A1 OS=Mus musculus OX=10090 GN=Fam8a1 PE=1 SV=1" 0 16.636 24 6 12 6 399 42.3 6.71 16812.9668 136181.293 10747.37207 2 2 1 membrane Pf06271 97863 ENSMUSG00000069237.8 C78339; Fam8a1 13 0 High P62267 40S ribosomal protein S23 OS=Mus musculus OX=10090 GN=Rps23 PE=1 SV=3 0 12.11 24 3 12 3 143 15.8 10.49 152307.6621 154444.9766 76988.32813 219606.5195 2 2 1 2 cell organization and biogenesis;metabolic process membrane;ribosome RNA binding;structural molecule activity Pf00164 66475 ENSMUSG00000049517.7 Rps23 13 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High Q8BGQ7 "Alanine--tRNA ligase, cytoplasmic OS=Mus musculus OX=10090 GN=Aars1 PE=1 SV=1" 0 21.793 10 7 12 7 968 106.8 5.67 49259.09033 176154.8936 7117.209961 193818.3564 2 4 1 5 Acetyl [N-Term] metabolic process;regulation of biological process cytoplasm;cytosol;membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding;RNA binding "Pf01411, Pf02272, Pf07973" 234734 ENSMUSG00000031960.14 Aars 8 Aminoacyl-tRNA biosynthesis 0 High Q52L67 Gpsn2 protein OS=Mus musculus OX=10090 GN=Tecr PE=1 SV=1 0 20.895 17 7 12 7 362 41.9 9.39 4982.6875 59778.08203 451911.9277 1 1 4 metabolic process cytoplasm;endoplasmic reticulum;membrane;nucleus catalytic activity Pf02544 106529 ENSMUSG00000031708.16 Tecr 8 0 High Q3U367 4-trimethylaminobutyraldehyde dehydrogenase OS=Mus musculus OX=10090 GN=Aldh9a1 PE=1 SV=1 0 17.517 11 5 12 5 518 55.9 7.46 140032.6343 37519.3877 53213.20898 5 3 2 metabolic process cytoplasm;cytosol;mitochondrion catalytic activity;nucleotide binding;protein binding Pf00171 56752 ENSMUSG00000026687.14 Aldh9a1 1 Carnitine synthesis "Histidine metabolism; Pyruvate metabolism; Arginine and proline metabolism; Tryptophan metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Lysine degradation; Fatty acid degradation; Glycolysis / Gluconeogenesis; beta-Alanine metabolism; Ascorbate and aldarate metabolism; Glycerolipid metabolism" 0 High Q3USW5 FAD-dependent oxidoreductase domain-containing protein 2 OS=Mus musculus OX=10090 GN=Foxred2 PE=2 SV=1 0 16.914 11 6 12 6 665 76 6.87 4840.155273 1 metabolic process endoplasmic reticulum;organelle lumen catalytic activity;nucleotide binding "Pf03486, Pf07992, Pf13450, Pf13738" 239554 ENSMUSG00000016552.13 Foxred2 15 0 High Q99M28 RNA-binding protein with serine-rich domain 1 OS=Mus musculus OX=10090 GN=Rnps1 PE=1 SV=1 0 10.325 10 3 12 3 305 34.2 11.84 15335.85962 58955.88818 3448.716553 13341.06421 2 3 1 2 metabolic process;regulation of biological process cytoplasm;nucleus RNA binding "Pf00076, Pf08777, Pf11608, Pf13893, Pf14259" 19826 ENSMUSG00000034681.16 Rnps1 17 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA surveillance pathway; RNA transport 0 High P39447 Tight junction protein ZO-1 OS=Mus musculus OX=10090 GN=Tjp1 PE=1 SV=2 0 26.701 9 10 12 10 1745 194.6 6.64 55417.25977 16278.94141 2397.041992 2 1 1 cellular homeostasis;response to stimulus cell surface;cytoplasm;cytosol;membrane;nucleus protein binding "Pf00018, Pf00595, Pf00625, Pf00791, Pf07653, Pf13180" 21872 ENSMUSG00000030516.14 Tjp1 7 Signaling by Hippo; c-src mediated regulation of Cx43 function and closure of gap junctions Adherens junction; Salmonella infection; Tight junction; Gap junction 0 High P80314 T-complex protein 1 subunit beta OS=Mus musculus OX=10090 GN=Cct2 PE=1 SV=4 0 21.292 19 8 12 8 535 57.4 6.4 99373.93506 76442.91016 6762.493286 6 3 2 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;cytosol nucleotide binding;protein binding Pf00118 12461 ENSMUSG00000034024.8 Cct2 10 Neutrophil degranulation; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Association of TriC/CCT with target proteins during biosynthesis 0 High Q91X51 Golgi reassembly-stacking protein 1 OS=Mus musculus OX=10090 GN=Gorasp1 PE=1 SV=3 0 11.227 21 5 12 5 446 46.9 4.65 1 1 9082.703125 1174724.094 51085.31641 393739.1182 1 5 2 5 cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;Golgi;membrane protein binding "Pf04495, Pf13180" 74498 ENSMUSG00000032513.8 Gorasp1 9 Golgi Cisternae Pericentriolar Stack Reorganization; COPI-mediated anterograde transport; COPII (Coat Protein 2) Mediated Vesicle Transport 0 High P39039 Mannose-binding protein A OS=Mus musculus OX=10090 GN=Mbl1 PE=1 SV=1 0 15.671 21 6 12 6 239 25.4 7.61 26766.85742 24078.82422 52833.73047 1 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus extracellular metal ion binding;protein binding Pf00059 17194 ENSMUSG00000037780.2 Mbl1 14 Staphylococcus aureus infection; Phagosome; Complement and coagulation cascades 0 High Q01279 Epidermal growth factor receptor OS=Mus musculus OX=10090 GN=Egfr PE=1 SV=1 0 22.141 7 7 12 7 1210 134.8 6.86 2317.226563 1 cell organization and biogenesis;cell proliferation;cellular component movement;development;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;endoplasmic reticulum;endosome;Golgi;membrane;nucleus;organelle lumen catalytic activity;enzyme regulator activity;nucleotide binding;protein binding;receptor activity;signal transducer activity "Pf00069, Pf00757, Pf01030, Pf07714, Pf14843" 13649 ENSMUSG00000020122.16 Egfr 11 "EGFR interacts with phospholipase C-gamma; Downregulation of ERBB2 signaling; GAB1 signalosome; Signaling by GPCR; EGFR downregulation; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; ERBB2 Regulates Cell Motility; SHC1 events in EGFR signaling; Interleukin-20 family signaling; Signaling by ERBB4; EGFR Transactivation by Gastrin; PI3K events in ERBB2 signaling; RAF/MAP kinase cascade; PTK6 promotes HIF1A stabilization; GRB2 events in EGFR signaling; ERBB2 Activates PTK6 Signaling; Signal transduction by L1; Cargo recognition for clathrin-mediated endocytosis; SHC1 events in ERBB2 signaling" Oxytocin signaling pathway; ErbB signaling pathway; FoxO signaling pathway; Endocytosis; Phospholipase D signaling pathway; Regulation of actin cytoskeleton; MAPK signaling pathway; MicroRNAs in cancer; Ras signaling pathway; Focal adhesion; Endometrial cancer; Breast cancer; Melanoma; Non-small cell lung cancer; Adherens junction; Dorso-ventral axis formation; Proteoglycans in cancer; Rap1 signaling pathway; HIF-1 signaling pathway; Pathways in cancer; Calcium signaling pathway; Hepatitis C; Pancreatic cancer; PI3K-Akt signaling pathway; GnRH signaling pathway; Gap junction; Glioma; EGFR tyrosine kinase inhibitor resistance; Central carbon metabolism in cancer; Choline metabolism in cancer; Estrogen signaling pathway; Cytokine-cytokine receptor interaction; Prostate cancer; Endocrine resistance; Bladder cancer 0 High P43406 Integrin alpha-V OS=Mus musculus OX=10090 GN=Itgav PE=1 SV=2 0 23.55 11 9 12 9 1044 115.3 5.63 49498.33203 35666.33203 213336.6335 2 2 6 cell differentiation;cell growth;cell organization and biogenesis;cellular component movement;cellular homeostasis;defense response;development;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytosol;membrane;nucleus metal ion binding;protein binding;transporter activity "Pf01839, Pf08441, Pf13517" 16410 ENSMUSG00000027087.11 Itgav 2 ECM proteoglycans; Molecules associated with elastic fibres; Cross-presentation of particulate exogenous antigens (phagosomes); Integrin cell surface interactions; VEGFA-VEGFR2 Pathway; Neutrophil degranulation; Signal transduction by L1; Syndecan interactions Hypertrophic cardiomyopathy (HCM); Regulation of actin cytoskeleton; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Focal adhesion; Small cell lung cancer; Dilated cardiomyopathy; Cell adhesion molecules (CAMs); Phagosome; Proteoglycans in cancer; Thyroid hormone signaling pathway; Pathways in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway 0 High Q61694 NADPH-dependent 3-keto-steroid reductase Hsd3b5 OS=Mus musculus OX=10090 GN=Hsd3b5 PE=1 SV=4 0 25.175 25 7 12 5 373 41.9 9.01 58277.76563 52194.37305 120836.8359 1 2 1 Met-loss [N-Term] metabolic process;response to stimulus endoplasmic reticulum;membrane;mitochondrion catalytic activity;nucleotide binding "Pf00106, Pf01073, Pf01370, Pf02719, Pf04321, Pf05368, Pf07993, Pf08659, Pf13460" 15496 ENSMUSG00000038092.6 Hsd3b5 3 Glucocorticoid biosynthesis; Androgen biosynthesis; Mineralocorticoid biosynthesis Steroid hormone biosynthesis; Ovarian steroidogenesis; Metabolic pathways; Aldosterone synthesis and secretion 0 High O88325 Alpha-N-acetylglucosaminidase OS=Mus musculus OX=10090 GN=Naglu PE=1 SV=1 0 17.629 10 5 12 5 739 82.5 6.61 172349.8281 540753.4463 38036.03906 152268.6921 1 2 1 5 cell organization and biogenesis;response to stimulus catalytic activity "Pf05089, Pf12971, Pf12972" 27419 ENSMUSG00000001751.9 Naglu 11 HS-GAG degradation Metabolic pathways; Lysosome; Glycosaminoglycan degradation 0 High P01791 Ig heavy chain V region HPCM6 OS=Mus musculus OX=10090 PE=1 SV=1 0 12.426 33 3 12 1 123 13.9 6.06 2 1 3 1 Pf07686 0 High Q8BMK4 Cytoskeleton-associated protein 4 OS=Mus musculus OX=10090 GN=Ckap4 PE=1 SV=2 0 9.905 9 4 12 4 575 63.7 5.64 8633.231445 19750.31641 1 1 cell surface;cytoplasm;cytoskeleton;cytosol;endoplasmic reticulum;membrane RNA binding Pf13166 216197 ENSMUSG00000046841.5 Ckap4 10 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Neutrophil degranulation; Post-translational protein phosphorylation; Surfactant metabolism Protein processing in endoplasmic reticulum 0 High O88844 Isocitrate dehydrogenase [NADP] cytoplasmic OS=Mus musculus OX=10090 GN=Idh1 PE=1 SV=2 0 12.107 14 5 12 5 414 46.6 7.17 75221.44336 60707.50586 48520.22119 4 3 3 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00180, Pf01960" 15926 ENSMUSG00000025950.16 Idh1 1 Neutrophil degranulation; NADPH regeneration Glutathione metabolism; Citrate cycle (TCA cycle); Metabolic pathways; Biosynthesis of amino acids; 2-Oxocarboxylic acid metabolism; Carbon metabolism; Peroxisome 0 High Q9D358 Low molecular weight phosphotyrosine protein phosphatase OS=Mus musculus OX=10090 GN=Acp1 PE=1 SV=3 0 12.417 24 3 11 3 158 18.2 6.74 12015.45215 7015.701172 2 1 metabolic process cytoplasm;cytosol;membrane catalytic activity Pf01451 11431; 102642088 ENSMUSG00000044573.15 Acp1; LOC631286; LOC102642088 12; 10 Thiamine metabolism; Metabolic pathways; Adherens junction 0 High P70694 Estradiol 17 beta-dehydrogenase 5 OS=Mus musculus OX=10090 GN=Akr1c6 PE=1 SV=1 0 10.604 17 5 11 4 323 37 8.28 1532.678955 27523.52344 35531.12451 1 1 2 metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus catalytic activity Pf00248 83702 ENSMUSG00000021210.15 Akr1c6 13 RA biosynthesis pathway; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; Signaling by GPCR; Retinoid metabolism and transport; Synthesis of bile acids and bile salts via 24-hydroxycholesterol; Synthesis of bile acids and bile salts via 27-hydroxycholesterol; Synthesis of Prostaglandins (PG) and Thromboxanes (TX) 1 High O88342 WD repeat-containing protein 1 OS=Mus musculus OX=10090 GN=Wdr1 PE=1 SV=3 0 14.509 9 4 11 4 606 66.4 6.6 2572.964111 2310.138428 1 1 cell differentiation;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process cytoplasm;cytoskeleton;cytosol protein binding "Pf00400, Pf04762, Pf08662, Pf14783" 22388 ENSMUSG00000005103.12 Wdr1 5 Platelet degranulation 0 High Q3UHJ0 AP2-associated protein kinase 1 OS=Mus musculus OX=10090 GN=Aak1 PE=1 SV=2 0 14.524 13 6 11 6 959 103.3 6.7 19342.19531 37504.12988 1 3 metabolic process;regulation of biological process;transport cytoplasm;membrane catalytic activity;nucleotide binding;protein binding "Pf00069, Pf07714" 269774 ENSMUSG00000057230.13 Aak1 6 Cargo recognition for clathrin-mediated endocytosis 0 High O88569 Heterogeneous nuclear ribonucleoproteins A2/B1 OS=Mus musculus OX=10090 GN=Hnrnpa2b1 PE=1 SV=2 0 11.435 15 5 11 5 353 37.4 8.95 175332.6113 163382.9766 43333.15625 4 3 2 cell organization and biogenesis;metabolic process;regulation of biological process;transport chromosome;cytoplasm;extracellular;membrane;nucleus;spliceosomal complex DNA binding;protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 53379 ENSMUSG00000004980.16 Hnrnpa2b1 6 mRNA Splicing - Major Pathway 0 High A0A494B923 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 OS=Mus musculus OX=10090 GN=Papss2 PE=1 SV=1 0 13.712 13 6 11 6 614 69.4 7.42 1784.081665 12826.99023 1 1 0 High Q3UID0 SWI/SNF complex subunit SMARCC2 OS=Mus musculus OX=10090 GN=Smarcc2 PE=1 SV=1 0 5.747 3 3 11 1 1130 124.6 5.47 7652.462402 1 cell organization and biogenesis;metabolic process;regulation of biological process nucleus DNA binding;protein binding Pf04433 68094 ENSMUSG00000025369.15 Smarcc2 10 0 High P17742 Peptidyl-prolyl cis-trans isomerase A OS=Mus musculus OX=10090 GN=Ppia PE=1 SV=2 0 12.761 28 4 11 4 164 18 7.9 37878.26953 209285.457 57630.74219 128296.1914 1 2 1 2 Met-loss [N-Term] cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;cytosol;extracellular;membrane;nucleus catalytic activity;protein binding;RNA binding Pf00160 268373 ENSMUSG00000071866.12 Ppia 11 Neutrophil degranulation; Basigin interactions 0 High F8VPL5 Mitogen-activated protein kinase kinase kinase kinase 4 OS=Mus musculus OX=10090 GN=Map4k4 PE=1 SV=2 0 10.622 4 4 11 3 1238 141.7 7.44 7139.398438 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm catalytic activity;nucleotide binding;protein binding;signal transducer activity "Pf00069, Pf00780, Pf07714" 26921 ENSMUSG00000026074.14 Map4k4 1 1 High Q9QZE5 Coatomer subunit gamma-1 OS=Mus musculus OX=10090 GN=Copg1 PE=1 SV=1 0 15.433 12 6 11 6 874 97.5 5.35 18150.71289 17764.79492 66549.88379 1 1 3 cellular component movement;transport cytoplasm;cytosol;Golgi;membrane structural molecule activity "Pf01602, Pf08752" 54161 ENSMUSG00000030058.17 Copg; Copg1 6 COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic 0 High Q8BTI8 Serine/arginine repetitive matrix protein 2 OS=Mus musculus OX=10090 GN=Srrm2 PE=1 SV=3 0 8.602 2 4 11 4 2703 294.7 12.03 2 2 335046.8281 20774.73438 52219.68262 4 1 4 metabolic process nucleus;spliceosomal complex protein binding;RNA binding 75956 ENSMUSG00000039218.16 Srrm2 17 mRNA Splicing - Major Pathway 0 High Q9DCS2 Methyltransferase-like 26 OS=Mus musculus OX=10090 GN=Mettl26 PE=1 SV=1 0 13.167 29 3 11 3 204 22.7 6.52 30433.21875 1 catalytic activity "Pf05175, Pf06080, Pf12847, Pf13649, Pf13659" 68347 ENSMUSG00000025731.15 0610011F06Rik; Mettl26 17 0 High Q8K382 DENN domain-containing protein 1A OS=Mus musculus OX=10090 GN=Dennd1a PE=1 SV=2 0 15.998 10 6 11 6 1016 111.5 6.79 20722.34277 4285.57959 3 1 regulation of biological process;transport cytosol;membrane protein binding "Pf02141, Pf03455, Pf03456" 227801 ENSMUSG00000035392.17 Dennd1a 2 RAB GEFs exchange GTP for GDP on RABs 0 High O08583 THO complex subunit 4 OS=Mus musculus OX=10090 GN=Alyref PE=1 SV=3 0 10.646 17 3 11 3 255 26.9 11.15 66501.82813 115384.248 29523.80078 1 2 1 Met-loss+Acetyl [N-Term] metabolic process;transport cytoplasm;nucleus;spliceosomal complex DNA binding;RNA binding "Pf00076, Pf13893, Pf14259" 21681 ENSMUSG00000025134.2 Alyref 11 mRNA surveillance pathway; Herpes simplex infection; Spliceosome; RNA transport 0 High Q91XD7 Protein disulfide isomerase Creld1 OS=Mus musculus OX=10090 GN=Creld1 PE=1 SV=1 0 22.536 17 6 11 6 420 45.7 5.02 8422.256836 12264.74756 10725.7168 1 2 1 membrane metal ion binding "Pf07645, Pf11938" 171508 ENSMUSG00000030284.11 Creld1 6 0 High O08553 Dihydropyrimidinase-related protein 2 OS=Mus musculus OX=10090 GN=Dpysl2 PE=1 SV=2 0 8.154 5 3 11 1 572 62.2 6.38 17634.37695 7016.016113 1 1 cell differentiation;cell organization and biogenesis;cellular component movement;development;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;membrane;mitochondrion catalytic activity;protein binding "Pf01979, Pf07969, Pf13147, Pf13594" 12934 ENSMUSG00000022048.8 Dpysl2 14 Recycling pathway of L1; CRMPs in Sema3A signaling Axon guidance 0 High Q8BL63 GPI-anchor transamidase OS=Mus musculus OX=10090 GN=Pigk PE=1 SV=1 0 23.958 26 6 11 6 442 49.8 6.54 15318.19238 1 metabolic process endoplasmic reticulum;membrane catalytic activity Pf01650 329777 ENSMUSG00000039047.17 Pigk 3 0 High A0A0B4J1J5 Immunoglobulin heavy variable V9-3 (Fragment) OS=Mus musculus OX=10090 GN=Ighv9-3 PE=1 SV=1 0 13.546 38 3 11 2 117 13 9.06 3 5 2806053.906 196724 106986.3438 66119.21875 3 1 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding "Pf00047, Pf07686" ENSMUSG00000096459.1 LOC674147 12 1 High Q3TWW8 Serine/arginine-rich splicing factor 6 OS=Mus musculus OX=10090 GN=Srsf6 PE=1 SV=1 0 6.881 7 3 11 2 339 39 11.46 50279.05322 152736.207 46663.31152 29867.44727 3 2 2 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus nucleus protein binding;RNA binding "Pf00076, Pf08777, Pf13893, Pf14259" 67996 ENSMUSG00000016921.14 Srsf6 2 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript Herpes simplex infection; Spliceosome 1 High B9EI38 RalBP1-associated Eps domain-containing protein 2 OS=Mus musculus OX=10090 GN=Reps2 PE=1 SV=1 0 16.623 12 5 11 4 648 70.6 7.25 cytoplasm metal ion binding;protein binding Pf12763 194590 ENSMUSG00000040855.15 Reps2 X Cargo recognition for clathrin-mediated endocytosis 0 High A0A0A0MQ73 Histone-lysine N-methyltransferase 2D OS=Mus musculus OX=10090 GN=Kmt2d PE=1 SV=1 0 11.324 2 7 11 7 5588 599.9 5.78 7211.999512 32934.25098 1 2 cell growth;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus nucleus catalytic activity;DNA binding;metal ion binding;protein binding "Pf00505, Pf00628, Pf00856, Pf05964, Pf05965, Pf13639, Pf13771, Pf13832, Pf15446" 381022 ENSMUSG00000048154.16 Kmt2d; Mll2 15 Lysine degradation 0 High Q9D9N8 Protease-associated domain-containing protein 1 OS=Mus musculus OX=10090 GN=Pradc1 PE=1 SV=1 0 7.444 24 4 11 4 188 21.1 5.72 120063.7354 3 extracellular Pf02225 73327 ENSMUSG00000030008.9 Pradc1 6 0 High A0A075B5L7 Immunoglobulin kappa variable 4-80 (Fragment) OS=Mus musculus OX=10090 GN=Igkv4-80 PE=4 SV=2 0 6.577 14 1 11 1 116 12.6 5.15 1 1 2 2 590890.25 495711.0938 49636.13281 1 1 1 response to stimulus "Pf00047, Pf07679, Pf07686" 545848 ENSMUSG00000076540.3 Igkv4-80 6 0 High Q9WVD5 Mitochondrial ornithine transporter 1 OS=Mus musculus OX=10090 GN=Slc25a15 PE=1 SV=1 0 20.18 36 6 11 6 301 32.8 8.85 93274.80469 1 transport membrane;mitochondrion transporter activity Pf00153 18408 ENSMUSG00000031482.9 Slc25a15 8 0 High E9QPX1 Collagen alpha-1(XVIII) chain OS=Mus musculus OX=10090 GN=Col18a1 PE=1 SV=1 0 12.711 4 5 11 5 1774 182.2 5.71 92418.31738 2 cell organization and biogenesis;regulation of biological process extracellular metal ion binding;protein binding;structural molecule activity "Pf01391, Pf01392, Pf06121, Pf06482, Pf13385" 12822 ENSMUSG00000001435.15 Col18a1 10 0 High A0A075B5Q6 Immunoglobulin heavy variable 5-9-1 OS=Mus musculus OX=10090 GN=Ighv5-9-1 PE=1 SV=1 0 10.859 33 3 11 3 116 13.1 8.87 3 1 5 1 2572798.859 360546.7109 76636.23438 169634.3828 3 2 1 2 ENSMUSG00000095210.2 12 0 High Q9Z0N1 "Eukaryotic translation initiation factor 2 subunit 3, X-linked OS=Mus musculus OX=10090 GN=Eif2s3x PE=1 SV=2" 0 19.021 13 4 11 4 472 51 8.4 44276.32422 9435.341797 96039.09375 43184.36133 2 1 1 3 Met-loss+Acetyl [N-Term] metabolic process cytoplasm catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00009, Pf03144, Pf09173" 26905 ENSMUSG00000035150.15 Eif2s3x X "L13a-mediated translational silencing of Ceruloplasmin expression; Recycling of eIF2:GDP; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ABC-family proteins mediated transport; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" RNA transport 0 High Q9QZD8 Mitochondrial dicarboxylate carrier OS=Mus musculus OX=10090 GN=Slc25a10 PE=1 SV=2 0 24.355 34 7 11 7 287 31.7 9.32 60471.33984 46363.55469 55381.25781 374027.7998 1 1 1 3 transport membrane;mitochondrion;nucleus transporter activity Pf00153 27376; 66838 ENSMUSG00000025792.9 Slc25a10; 0610009L18Rik 11 Organic anion transporters; Sulfide oxidation to sulfate; Gluconeogenesis Proximal tubule bicarbonate reclamation 0 High P62880 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 OS=Mus musculus OX=10090 GN=Gnb2 PE=1 SV=3 0 24.764 36 8 11 8 340 37.3 6 303120.3093 12176.16797 24209.5708 3 1 2 Met-loss+Acetyl [N-Term] regulation of biological process;response to stimulus cytoplasm;membrane catalytic activity;protein binding;signal transducer activity Pf00400 14693 ENSMUSG00000029713.15 Gnb2 5 "Glucagon signaling in metabolic regulation; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Adrenaline,noradrenaline inhibits insulin secretion; Activation of G protein gated Potassium channels; Vasopressin regulates renal water homeostasis via Aquaporins; Glucagon-type ligand receptors; Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits" Morphine addiction; Cholinergic synapse; Retrograde endocannabinoid signaling; Dopaminergic synapse; Ras signaling pathway; GABAergic synapse; Chemokine signaling pathway; Glutamatergic synapse; Pathways in cancer; Alcoholism; PI3K-Akt signaling pathway; Circadian entrainment; Serotonergic synapse 0 High E9Q1Y9 Keratin 83 OS=Mus musculus OX=10090 GN=Krt83 PE=1 SV=1 0 15.482 11 5 11 2 479 52.8 5.74 1 1 regulation of biological process;transport catalytic activity;motor activity;structural molecule activity "Pf00038, Pf01576, Pf05557, Pf05911, Pf07888, Pf07926, Pf11559, Pf13514" 100126226 ENSMUSG00000067613.5 5430421N21Rik; Krt83 15 Formation of the cornified envelope 0 High A0A0U1RNL7 Protein-serine/threonine kinase OS=Mus musculus OX=10090 GN=Bckdk PE=1 SV=1 0 24.862 29 6 11 6 335 38 9.42 1 1 568164.9141 142197.0386 21493.13867 160368.3867 3 3 2 4 metabolic process mitochondrion catalytic activity Pf10436 ENSMUSG00000030802.14 7 0 High P21126 Ubiquitin-like protein 4A OS=Mus musculus OX=10090 GN=Ubl4a PE=1 SV=1 0 15.975 36 5 11 5 157 17.8 8.44 10719.46484 164338.5352 71552.60938 47289.8125 1 3 1 2 transport cytoplasm;cytosol;membrane;nucleus protein binding "Pf00240, Pf11976" 27643; 100169864 ENSMUSG00000015290.15 Ubl4; Ubl4a; Slc10a3-ubl4; Gm38419; SlcUbl4a; Gm44504 X 0 High A0A087WS46 Eukaryotic translation elongation factor 1 beta 2 OS=Mus musculus OX=10090 GN=Eef1b2 PE=1 SV=1 0 11.925 20 3 10 3 184 20.1 4.56 57253.47852 49247.53809 25578.86035 2 2 2 metabolic process RNA binding Pf00736 ENSMUSG00000025967.16 1 0 High Q8VDN2 Sodium/potassium-transporting ATPase subunit alpha-1 OS=Mus musculus OX=10090 GN=Atp1a1 PE=1 SV=1 0 11.338 5 4 10 4 1023 112.9 5.45 28234.07031 15914.75293 79679.85938 1 2 3 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport endoplasmic reticulum;endosome;Golgi;membrane catalytic activity;metal ion binding;nucleotide binding;protein binding;transporter activity "Pf00122, Pf00689, Pf00690, Pf00702, Pf08282, Pf12710, Pf13246" 11928 ENSMUSG00000033161.10 Atp1a1 3 Ion transport by P-type ATPases; Ion homeostasis Pancreatic secretion; Carbohydrate digestion and absorption; Mineral absorption; Protein digestion and absorption; Endocrine and other factor-regulated calcium reabsorption; Thyroid hormone synthesis; Thyroid hormone signaling pathway; Proximal tubule bicarbonate reclamation; cGMP-PKG signaling pathway; Bile secretion; Salivary secretion; Cardiac muscle contraction; cAMP signaling pathway; Gastric acid secretion; Insulin secretion; Adrenergic signaling in cardiomyocytes; Aldosterone-regulated sodium reabsorption 0 High Q8JZZ0 UDP-glucuronosyltransferase 3A2 OS=Mus musculus OX=10090 GN=Ugt3a2 PE=1 SV=2 0 15.878 18 7 10 7 523 59.6 7.53 18330.28125 23240.28125 5795.864258 1 1 2 metabolic process;response to stimulus membrane catalytic activity "Pf00201, Pf04101" 223337 ENSMUSG00000049152.11 Ugt3a2 15 0 High D3YZJ1 Sequestosome-1 OS=Mus musculus OX=10090 GN=Sqstm1 PE=1 SV=1 0.002 5.124 7 1 10 1 382 41.7 7.72 metal ion binding;protein binding "Pf00564, Pf00569" ENSMUSG00000015837.15 11 0 High A2A9M4 Dedicator of cytokinesis protein 7 OS=Mus musculus OX=10090 GN=Dock7 PE=1 SV=2 0 13.652 3 4 10 4 2130 241.3 6.76 124638.3809 135378.3984 44993.41016 3 2 2 cell differentiation;cell organization and biogenesis;development;regulation of biological process;response to stimulus protein binding "Pf06920, Pf11878, Pf14429" 67299 ENSMUSG00000028556.15 Dock7 4 MET activates RAP1 and RAC1 0 High Q6P8N8 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Mus musculus OX=10090 GN=Clpx PE=1 SV=1" 0 14.178 12 6 10 6 620 67.3 7.55 34363.79053 2978.280029 18079.70117 3 1 2 metabolic process;regulation of biological process cytosol;membrane;mitochondrion;organelle lumen catalytic activity;enzyme regulator activity;metal ion binding;nucleotide binding;protein binding "Pf00004, Pf00158, Pf01078, Pf05729, Pf07724, Pf07726, Pf07728, Pf10431, Pf13191, Pf13401, Pf14532" 270166 ENSMUSG00000015357.10 Clpx 9 0 High Q9CQ62 "2,4-dienoyl-CoA reductase, mitochondrial OS=Mus musculus OX=10090 GN=Decr1 PE=1 SV=1" 0 8.113 13 3 10 3 335 36.2 8.95 2 2 318297.6797 195556.4141 175825.4531 165046.4453 2 2 1 2 cell organization and biogenesis;metabolic process cytosol;mitochondrion;nucleus catalytic activity;nucleotide binding "Pf00106, Pf08659, Pf13561" 67460 ENSMUSG00000028223.8 Decr1 4 mitochondrial fatty acid beta-oxidation of unsaturated fatty acids 0 High P99029 "Peroxiredoxin-5, mitochondrial OS=Mus musculus OX=10090 GN=Prdx5 PE=1 SV=2" 0 11.939 23 3 10 3 210 21.9 8.85 1 1 90761.18555 300436.0547 169412.2227 72403.91406 2 3 2 3 cell death;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;mitochondrion;nucleus;organelle lumen antioxidant activity;catalytic activity;DNA binding;enzyme regulator activity;protein binding "Pf00578, Pf08534" 54683 ENSMUSG00000024953.16 Prdx5 19 Detoxification of Reactive Oxygen Species; TP53 Regulates Metabolic Genes Peroxisome 0 High Q8VCH6 Delta(24)-sterol reductase OS=Mus musculus OX=10090 GN=Dhcr24 PE=1 SV=1 0 17.561 15 6 10 6 516 60.1 8.16 38412.49756 31234.17041 29352.69873 3 2 2 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;endoplasmic reticulum;Golgi;membrane;nucleus catalytic activity;nucleotide binding;protein binding Pf01565 74754 ENSMUSG00000034926.3 Dhcr24 4 Cholesterol biosynthesis via desmosterol; Cholesterol biosynthesis via lathosterol Steroid biosynthesis; Metabolic pathways 0 High P62196 26S proteasome regulatory subunit 8 OS=Mus musculus OX=10090 GN=Psmc5 PE=1 SV=1 0 15.332 18 5 10 4 406 45.6 7.55 24167.7373 30554.06445 26614.31836 75500.1377 2 1 1 3 metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus;proteasome catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00004, Pf00910, Pf01057, Pf01078, Pf05496, Pf06068, Pf06414, Pf07724, Pf07726, Pf07728, Pf13191, Pf13207, Pf13401" 19184 ENSMUSG00000020708.12 Psmc5 11 The role of GTSE1 in G2/M progression after G2 checkpoint; CDT1 association with the CDC6:ORC:origin complex; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Degradation of beta-catenin by the destruction complex; Autodegradation of the E3 ubiquitin ligase COP1; UCH proteinases; MAPK6/MAPK4 signaling; SCF-beta-TrCP mediated degradation of Emi1; CDK-mediated phosphorylation and removal of Cdc6; Separation of Sister Chromatids; SCF(Skp2)-mediated degradation of p27/p21; GLI3 is processed to GLI3R by the proteasome; Ub-specific processing proteases; Regulation of ornithine decarboxylase (ODC); Activation of NF-kappaB in B cells; FCERI mediated NF-kB activation; Degradation of GLI1 by the proteasome; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Hedgehog ligand biogenesis; Downstream TCR signaling; Autodegradation of Cdh1 by Cdh1:APC/C; Regulation of RAS by GAPs; Interleukin-1 family signaling; Asymmetric localization of PCP proteins; G2/M Checkpoints; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Regulation of PTEN stability and activity; Ubiquitin-dependent degradation of Cyclin D1; NIK-->noncanonical NF-kB signaling; Removal of licensing factors from origins; M/G1 Transition; Interleukin-20 family signaling; Regulation of RUNX2 expression and activity; Cross-presentation of soluble exogenous antigens (endosomes); ABC-family proteins mediated transport; APC/C:Cdc20 mediated degradation of Securin; Regulation of DNA replication; Dectin-1 mediated noncanonical NF-kB signaling; Antigen processing: Ubiquitination & Proteasome degradation; Orc1 removal from chromatin; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of RUNX3 expression and activity; Hedgehog 'on' state; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Degradation of DVL; Degradation of AXIN Proteasome; Epstein-Barr virus infection 1 Medium D3Z4W5 RIKEN cDNA 1700074P13 gene (Fragment) OS=Mus musculus OX=10090 GN=1700074P13Rik PE=3 SV=1 0.01 2.224 4 1 10 1 176 20.1 5.06 2640.951416 8145.751465 1 1 metabolic process Golgi catalytic activity Pf00089 ENSMUSG00000029883.12 6 0 High Q6A0A9 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Mus musculus OX=10090 GN=FAM120A PE=1 SV=2 0 18.213 7 6 10 6 1112 121.6 8.92 26033.82495 69373.95752 23343.39648 61677.06445 3 3 2 2 cytoplasm;cytosol;membrane;nucleus RNA binding Pf13458 218236 ENSMUSG00000038014.7 Fam120a 13 0 High Q9QZ25 Vascular non-inflammatory molecule 3 OS=Mus musculus OX=10090 GN=Vnn3 PE=1 SV=3 0 21.753 21 7 10 7 500 56.3 6.29 111488.7266 288081.9063 200198.4063 1 1 1 metabolic process membrane catalytic activity Pf00795 26464 ENSMUSG00000020010.7 Vnn3 10 Post-translational modification: synthesis of GPI-anchored proteins Pantothenate and CoA biosynthesis 0 High Q5U4C1 G-protein coupled receptor-associated sorting protein 1 OS=Mus musculus OX=10090 GN=Gprasp1 PE=1 SV=1 0 16.481 6 6 10 6 1347 151.7 5.08 37355.19824 18059.11523 2 1 metabolic process;regulation of biological process;transport cytoplasm;cytosol;nucleus protein binding Pf04826 67298 ENSMUSG00000043384.15 Gprasp1 X 0 High Q91WP0 Mannan-binding lectin serine protease 2 OS=Mus musculus OX=10090 GN=Masp2 PE=1 SV=1 0 19.793 14 7 10 7 685 75.5 6.07 236683.6641 221926 130032.1406 2 2 1 defense response;metabolic process;regulation of biological process;response to stimulus extracellular catalytic activity;metal ion binding;protein binding "Pf00084, Pf00089, Pf00431, Pf07645, Pf12662, Pf14670" 17175 ENSMUSG00000028979.17 Masp2 4 Ficolins bind to repetitive carbohydrate structures on the target cell surface; Lectin pathway of complement activation Staphylococcus aureus infection; Complement and coagulation cascades 0 High Q3UIR3 E3 ubiquitin-protein ligase DTX3L OS=Mus musculus OX=10090 GN=Dtx3l PE=1 SV=1 0 19.19 14 6 10 6 748 83 8.09 9576.973633 19883.20508 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;endosome;nucleus;vacuole catalytic activity;enzyme regulator activity;metal ion binding;protein binding "Pf00097, Pf05290, Pf12678, Pf13639, Pf13920, Pf13923, Pf14835" 209200 ENSMUSG00000049502.16 Dtx3l 16 Antigen processing: Ubiquitination & Proteasome degradation Notch signaling pathway 0 High P25688 Uricase OS=Mus musculus OX=10090 GN=Uox PE=1 SV=2 0 15.482 27 6 10 6 303 35 8.35 289141.6084 592664.4524 163508.2344 227347.7344 2 2 1 2 Met-loss+Acetyl [N-Term] metabolic process mitochondrion catalytic activity Pf01014 22262 ENSMUSG00000028186.14 Uox 3 Caffeine metabolism; Metabolic pathways; Purine metabolism 0 High Q3TEX6 Fanconi anemia group B protein homolog OS=Mus musculus OX=10090 GN=Fancb PE=1 SV=1 0 15.236 8 7 10 7 853 96.9 5.96 8022.620605 3133.785889 1 1 metabolic process;regulation of biological process;response to stimulus nucleus 237211 ENSMUSG00000047757.16 Fancb X Fanconi Anemia Pathway Fanconi anemia pathway 0 High A0A1B0GSD0 Transthyretin (Fragment) OS=Mus musculus OX=10090 GN=Urah PE=1 SV=1 0 21.287 38 4 10 4 153 17.1 6.4 10559.12012 47960.71094 19618.87109 1 1 1 Acetyl [N-Term] extracellular protein binding Pf00576 ENSMUSG00000025481.12 7 0 High O08677 Kininogen-1 OS=Mus musculus OX=10090 GN=Kng1 PE=1 SV=1 0 21.589 13 7 10 7 661 73.1 6.54 25334.83398 603549.8281 54887.00098 1 4 3 cellular homeostasis;coagulation;defense response;regulation of biological process;response to stimulus extracellular enzyme regulator activity;protein binding Pf00031 16644 Kng1 16 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Peptide ligand-binding receptors; Intrinsic Pathway of Fibrin Clot Formation; G alpha (i) signalling events; Post-translational protein phosphorylation; Platelet degranulation ; Gastrin-CREB signalling pathway via PKC and MAPK Complement and coagulation cascades 0 Medium P98197 Probable phospholipid-transporting ATPase IH OS=Mus musculus OX=10090 GN=Atp11a PE=1 SV=1 0.022 1.65 1 1 10 1 1187 135.4 6.48 1 1 109016.3125 102763.0391 149707.0313 217254.9219 1 1 1 1 cell organization and biogenesis;transport endoplasmic reticulum;endosome;membrane catalytic activity;metal ion binding;nucleotide binding;transporter activity "Pf00122, Pf00702, Pf08282, Pf13246" 50770 ENSMUSG00000031441.15 Atp11a 8 Neutrophil degranulation 0 High E9QNN1 ATP-dependent RNA helicase A OS=Mus musculus OX=10090 GN=Dhx9 PE=1 SV=1 0 8.499 4 4 10 4 1384 149.6 6.83 60402.53809 64712.08789 7070.171875 27888.90039 3 2 1 2 cell death;cell differentiation;cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;membrane;nucleus;ribosome catalytic activity;DNA binding;metal ion binding;nucleotide binding;protein binding;RNA binding "Pf00035, Pf00270, Pf00271, Pf04408, Pf07717" 13211 ENSMUSG00000042699.11 Dhx9 1 DEx/H-box helicases activate type I IFN and inflammatory cytokines production ; Activated TLR4 signalling; mRNA Splicing - Major Pathway; TAK1 activates NFkB by phosphorylation and activation of IKKs complex; RIP-mediated NFkB activation via ZBP1; TRAF6 mediated NF-kB activation; Interleukin-1 family signaling 0 High Q1W617 Protein Shroom4 OS=Mus musculus OX=10090 GN=Shroom4 PE=1 SV=1 0.005 3.004 1 1 10 1 1475 163.1 6.73 1 2 324394.0625 763660.3555 596480.0547 557534.1348 1 1 1 1 cell organization and biogenesis;development cytoplasm;cytoskeleton;membrane protein binding "Pf00595, Pf08687" 208431 ENSMUSG00000068270.15 Shroom4 X Tight junction 0 High Q6IME9 "Keratin, type II cytoskeletal 72 OS=Mus musculus OX=10090 GN=Krt72 PE=3 SV=1" 0 11.566 7 3 10 1 520 56.7 7.4 1 1 417417.1875 13546.97852 25982.77734 1 1 1 catalytic activity;motor activity;protein binding;structural molecule activity "Pf00038, Pf01576, Pf09728, Pf12128, Pf13514" 105866 ENSMUSG00000056605.6 Krt72; Krt72-ps 15 Formation of the cornified envelope 0 High O54724 Caveolae-associated protein 1 OS=Mus musculus OX=10090 GN=Cavin1 PE=1 SV=1 0 14.479 22 6 10 6 392 43.9 5.52 4 3 1 5 4 1 1116570.258 1469511.227 415090.8594 292499.9453 4 4 3 4 metabolic process;regulation of biological process cytoplasm;cytosol;endoplasmic reticulum;membrane;mitochondrion;nucleus protein binding;RNA binding Pf15237 19285 ENSMUSG00000004044.9 Ptrf; Cavin1 11 RNA Polymerase I Transcription Termination 0 High E9Q0U7 Heat shock protein 105 kDa OS=Mus musculus OX=10090 GN=Hsph1 PE=1 SV=1 0 19.741 12 7 10 6 817 91.6 5.59 96135.00391 34246.39648 14246.61133 35573.94189 2 2 1 5 nucleotide binding Pf00012 ENSMUSG00000029657.15 5 1 High A0A087WR97 TAR DNA-binding protein 43 (Fragment) OS=Mus musculus OX=10090 GN=Tardbp PE=1 SV=1 0 14.714 31 4 10 4 243 26.7 7.77 1 1 82968.04883 170722.9258 39869.21582 55430.88672 3 2 2 2 metabolic process;regulation of biological process RNA binding "Pf00076, Pf14259" ENSMUSG00000041459.15 4 0 High D3Z7X0 "Acyl-Coenzyme A dehydrogenase family, member 12 OS=Mus musculus OX=10090 GN=Acad12 PE=1 SV=1" 0 13.776 13 5 10 5 555 61.4 9.36 1 1 232964.0283 497174.0625 416004.1602 299291.1768 3 4 3 5 metabolic process mitochondrion catalytic activity;nucleotide binding "Pf00441, Pf02770, Pf02771, Pf08028" 338350 ENSMUSG00000042647.13 Acad12 5 Mitochondrial Fatty Acid Beta-Oxidation 0 High Q61586 "Glycerol-3-phosphate acyltransferase 1, mitochondrial OS=Mus musculus OX=10090 GN=Gpam PE=1 SV=2" 0 20.664 11 7 10 7 827 93.6 7.84 230375.6912 66058.40625 94669.14551 2 1 2 defense response;metabolic process;regulation of biological process;response to stimulus;transport membrane;mitochondrion catalytic activity Pf01553 14732 ENSMUSG00000024978.10 Gpam 19 Triglyceride biosynthesis; Synthesis of PA Metabolic pathways; Glycerophospholipid metabolism; Glycerolipid metabolism 0 High B7ZBV9 Potassium voltage-gated channel subfamily KQT member 2 OS=Mus musculus OX=10090 GN=Kcnq2 PE=1 SV=1 0 14.925 11 6 10 6 870 95.7 9.23 38955.64453 93992.33154 42003.52661 1 3 3 regulation of biological process;transport cell surface;membrane protein binding;transporter activity "Pf00520, Pf03520, Pf07885, Pf11956" 16536 ENSMUSG00000016346.17 Kcnq2 2 Voltage gated Potassium channels 0 High P84104 Serine/arginine-rich splicing factor 3 OS=Mus musculus OX=10090 GN=Srsf3 PE=1 SV=1 0.002 3.86 14 2 10 1 164 19.3 11.65 1 1 182859.6719 84300.41406 77191.57813 89197.96094 1 1 1 1 metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;nucleus protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 20383 ENSMUSG00000071172.12 Srsf3 17 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript Herpes simplex infection; Spliceosome 0 High P20801 "Troponin C, skeletal muscle OS=Mus musculus OX=10090 GN=Tnnc2 PE=1 SV=2" 0 24.864 44 5 9 5 160 18.1 4.2 87203.45996 136735.8525 22456.48242 111481.3438 2 2 1 2 regulation of biological process metal ion binding;protein binding "Pf00036, Pf13202, Pf13405, Pf13499, Pf13833" 21925 ENSMUSG00000017300.9 Tnnc2 2 Striated Muscle Contraction Calcium signaling pathway 0 High Q62172 RalA-binding protein 1 OS=Mus musculus OX=10090 GN=Ralbp1 PE=1 SV=4 0 14.789 12 6 9 6 648 75 5.92 14151.71973 109189.209 33980.62207 1 2 2 cell organization and biogenesis;regulation of biological process;response to stimulus;transport membrane catalytic activity;enzyme regulator activity;protein binding;transporter activity Pf00620 19765 ENSMUSG00000024096.16 Ralbp1 17 Rho GTPase cycle Ras signaling pathway; Pathways in cancer; Pancreatic cancer 0 High Q8R2P8 Lysine--tRNA ligase OS=Mus musculus OX=10090 GN=Kars PE=1 SV=1 0 10.118 7 4 9 4 624 71.2 6.43 5751.673706 4256.564941 2 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;extracellular;membrane;mitochondrion;nucleus catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00152, Pf00587, Pf01336" 85305 ENSMUSG00000031948.14 Kars 8 0 High Q9JIF7 Coatomer subunit beta OS=Mus musculus OX=10090 GN=Copb1 PE=1 SV=1 0 13.938 10 6 9 6 953 107 6 11111.43066 15118.61426 7830.310547 1 1 1 transport cytoplasm;cytosol;Golgi;membrane structural molecule activity "Pf01602, Pf07718, Pf14806" 70349 ENSMUSG00000030754.9 Copb1 7 COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic; Neutrophil degranulation 0 High C5NSA7 "Tryptophan 2,3-dioxygenase OS=Mus musculus OX=10090 GN=Tdo2 PE=1 SV=1" 0 14.707 14 5 9 5 387 45.8 6.67 cell organization and biogenesis;metabolic process catalytic activity;metal ion binding;protein binding Pf03301 56720 ENSMUSG00000028011.16 Tdo2 3 0 High Q921K2 Poly [ADP-ribose] polymerase OS=Mus musculus OX=10090 GN=Parp1 PE=1 SV=1 0 22.599 10 7 9 7 1014 112.7 8.95 35279.57178 61308.78516 3 1 cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;mitochondrion;nucleus catalytic activity;DNA binding;metal ion binding;nucleotide binding;protein binding;RNA binding "Pf00533, Pf00644, Pf00645, Pf02877, Pf05406, Pf08063" 11545 ENSMUSG00000026496.11 Parp1 1 HDR through MMEJ (alt-NHEJ); DNA Damage Recognition in GG-NER; Formation of Incision Complex in GG-NER; Downregulation of SMAD2/3:SMAD4 transcriptional activity; Dual Incision in GG-NER; POLB-Dependent Long Patch Base Excision Repair; SUMOylation of DNA damage response and repair proteins NF-kappa B signaling pathway; Base excision repair; Apoptosis 0 High P48758 Carbonyl reductase [NADPH] 1 OS=Mus musculus OX=10090 GN=Cbr1 PE=1 SV=3 0 12.06 18 4 9 4 277 30.6 8.31 1 1 268731.833 65663.23633 11587.4873 3 2 1 Met-loss+Acetyl [N-Term] metabolic process cytoplasm;membrane;nucleus catalytic activity "Pf00106, Pf01370, Pf08659, Pf13561" 12408 ENSMUSG00000051483.8 Cbr1 16 Synthesis of Prostaglandins (PG) and Thromboxanes (TX) Metabolic pathways; Arachidonic acid metabolism; Chemical carcinogenesis; Metabolism of xenobiotics by cytochrome P450 0 High Q8VDJ3 Vigilin OS=Mus musculus OX=10090 GN=Hdlbp PE=1 SV=1 0 18.06 6 6 9 6 1268 141.7 6.87 72897.57178 40490.79688 23638.4668 17260.43896 3 2 1 3 Met-loss+Acetyl [N-Term] metabolic process;transport cytoplasm;cytosol;membrane;nucleus protein binding;RNA binding "Pf00013, Pf13014, Pf14611" 110611 ENSMUSG00000034088.15 Hdlbp 1 HDL clearance 0 High Q9D646 "Keratin, type I cuticular Ha4 OS=Mus musculus OX=10090 GN=Krt34 PE=2 SV=1" 0 15.274 14 5 9 1 392 44.5 4.79 1 1 152424.4375 32607.70703 1 1 catalytic activity;motor activity;structural molecule activity "Pf00038, Pf01576, Pf13514" 16672 ENSMUSG00000043485.2 Krt34 11 Formation of the cornified envelope 0 High A0A0R4J1T1 Sorbin and SH3 domain-containing protein 2 (Fragment) OS=Mus musculus OX=10090 GN=Sorbs2 PE=1 SV=1 0 16.254 8 7 9 7 1134 127.7 8.12 113154.8545 281664.457 6522.943848 4 3 1 cell growth;cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane protein binding;RNA binding "Pf00018, Pf02208, Pf07653, Pf14604" 234214 ENSMUSG00000031626.17 Sorbs2 8 0 High A0A0A6YW37 Immunoglobulin heavy variable V1-9 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-9 PE=4 SV=1 0 16.503 34 2 9 2 117 13 7.28 1 2 2 2 2723278.563 1927688.906 97145.41406 2 2 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000094694.6 12 0 High Q8BH64 EH domain-containing protein 2 OS=Mus musculus OX=10090 GN=Ehd2 PE=1 SV=1 0 15.659 17 7 9 7 543 61.1 6.51 7 9 1698418.391 217063.7129 132243.2842 97711.89111 6 4 3 4 cell organization and biogenesis;regulation of biological process;transport cytoplasm;cytoskeleton;cytosol;endosome;membrane catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00350, Pf01926, Pf12763" 259300 ENSMUSG00000074364.6 Ehd2 7 Factors involved in megakaryocyte development and platelet production Endocytosis 0 High A0A0R4J0I8 Beta-secretase 2 OS=Mus musculus OX=10090 GN=Bace2 PE=1 SV=1 0 14.004 13 5 9 5 514 55.8 5.08 8552.060547 1 metabolic process;regulation of biological process endoplasmic reticulum;endosome;Golgi;membrane catalytic activity "Pf00026, Pf14541, Pf14543" 56175 ENSMUSG00000040605.6 Bace2 16 Alzheimer's disease 0 High A0A1B0GSU0 Aldehyde dehydrogenase family 16 member A1 OS=Mus musculus OX=10090 GN=Aldh16a1 PE=1 SV=1 0 17.838 7 5 9 5 802 84.7 6.32 5221.223145 1 metabolic process membrane catalytic activity "Pf00171, Pf07368" 69748 ENSMUSG00000007833.15 Aldh16a1 7 0 High Q61033 "Lamina-associated polypeptide 2, isoforms alpha/zeta OS=Mus musculus OX=10090 GN=Tmpo PE=1 SV=4" 0 13.416 11 6 9 3 693 75.1 8.05 357026.5 6 Met-loss [N-Term] regulation of biological process chromosome;membrane;nucleus DNA binding;protein binding "Pf03020, Pf08198, Pf11560" 21917 ENSMUSG00000019961.17 Tmpo 10 4 High Q99L04 Dehydrogenase/reductase SDR family member 1 OS=Mus musculus OX=10090 GN=Dhrs1 PE=1 SV=1 0 17.689 30 6 9 6 313 34 8.35 91480.88525 163299.2969 13532.75879 3 1 1 metabolic process endoplasmic reticulum;membrane;mitochondrion catalytic activity "Pf00106, Pf08659, Pf13460, Pf13561" 52585 ENSMUSG00000002332.15 Dhrs1 14 0 High Q61029 "Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma OS=Mus musculus OX=10090 GN=Tmpo PE=1 SV=4" 0 12.036 17 5 9 2 452 50.3 9.45 Met-loss [N-Term] regulation of biological process chromosome;membrane;nucleus DNA binding;protein binding "Pf03020, Pf08198" 21917 ENSMUSG00000019961.17 Tmpo 10 0 High Q9WTZ1 RING-box protein 2 OS=Mus musculus OX=10090 GN=Rnf7 PE=3 SV=1 0 8.513 39 3 9 3 113 12.7 5.44 25728.64844 55219.59375 6266.503418 2 2 1 Met-loss+Acetyl [N-Term] cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;nucleus catalytic activity;metal ion binding;protein binding "Pf12678, Pf12861, Pf13639" 19823 ENSMUSG00000051234.6 Rnf7 9 Neddylation Ubiquitin mediated proteolysis 0 High Q8CFI7 DNA-directed RNA polymerase II subunit RPB2 OS=Mus musculus OX=10090 GN=Polr2b PE=1 SV=2 0 12.94 7 6 9 6 1174 133.8 6.87 687438.7832 99356.26953 177612.9688 309150.126 2 4 1 2 metabolic process membrane;nucleus catalytic activity;DNA binding;metal ion binding;RNA binding "Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf04566, Pf04567" 231329 ENSMUSG00000029250.5 Polr2b 5 mRNA Capping; RNA Polymerase II Transcription Initiation; Transcriptional regulation by small RNAs; RNA Polymerase II Pre-transcription Events; Formation of RNA Pol II elongation complex ; mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; RNA Pol II CTD phosphorylation and interaction with CE; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Dual incision in TC-NER; RNA polymerase II transcribes snRNA genes; Formation of the Early Elongation Complex; TP53 Regulates Transcription of DNA Repair Genes; Gap-filling DNA repair synthesis and ligation in TC-NER; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA polymerase; Epstein-Barr virus infection; Metabolic pathways; Purine metabolism; Huntington's disease; Pyrimidine metabolism 0 High P00186 Cytochrome P450 1A2 OS=Mus musculus OX=10090 GN=Cyp1a2 PE=1 SV=1 0 12.986 17 5 9 5 513 58.1 8.76 26880.64941 183854.3379 3083.110107 2 2 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;endoplasmic reticulum;membrane;mitochondrion catalytic activity;metal ion binding;protein binding Pf00067 13077; 13076 ENSMUSG00000032310.4 Cyp1a2; Cyp1a1 9 Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET); Aflatoxin activation and detoxification; Methylation; Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE); Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 Caffeine metabolism; Steroid hormone biosynthesis; Tryptophan metabolism; Drug metabolism - cytochrome P450; Retinol metabolism; Metabolic pathways; Linoleic acid metabolism; Chemical carcinogenesis; Metabolism of xenobiotics by cytochrome P450 0 High Q8BXA5 Cleft lip and palate transmembrane protein 1-like protein OS=Mus musculus OX=10090 GN=Clptm1l PE=1 SV=1 0 14.951 15 6 9 6 539 62.1 8.84 22029.98633 40299.65381 2 3 cell death membrane Pf05602 218335 ENSMUSG00000021610.7 Clptm1l 13 0 High P34927 Asialoglycoprotein receptor 1 OS=Mus musculus OX=10090 GN=Asgr1 PE=1 SV=4 0 12.713 21 5 9 5 284 32.6 6.44 65955.01172 13954.5625 14823.19922 2 1 1 cell communication;response to stimulus;transport membrane metal ion binding;protein binding;receptor activity "Pf00059, Pf03954, Pf05622" 11889 ENSMUSG00000020884.15 Asgr1 11 Asparagine N-linked glycosylation Thyroid hormone synthesis 0 High H3BK03 Serum paraoxonase/arylesterase 1 (Fragment) OS=Mus musculus OX=10090 GN=Pon1 PE=1 SV=9 0 16.07 40 6 9 1 256 28.7 5.45 6780.149414 97984.92969 1 1 0 High A0A0R4J039 Histidine-rich glycoprotein OS=Mus musculus OX=10090 GN=Hrg PE=1 SV=1 0 9.151 8 4 9 4 536 60.4 7.61 68507.38184 19389.31836 4 1 coagulation;defense response;regulation of biological process;response to stimulus;transport cell surface;endosome;extracellular;membrane;vacuole enzyme regulator activity;metal ion binding;protein binding 94175 ENSMUSG00000022877.8 Hrg 16 Dissolution of Fibrin Clot; Platelet degranulation 0 High Q6AXB7 Fragile X mental retardation syndrome 1 homolog OS=Mus musculus OX=10090 GN=Fmr1 PE=1 SV=1 0 11.006 10 4 9 2 614 68.8 7.42 40758.23584 95256.07031 12080.15332 2 1 1 cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport chromosome;cytoplasm;cytosol;endoplasmic reticulum;membrane;nucleus protein binding;RNA binding;translation regulator activity "Pf00013, Pf05641, Pf12235, Pf13014" 14265 ENSMUSG00000000838.17 Fmr1 X RNA transport 0 High A0A0G2JGW8 Immunoglobulin kappa chain variable 12-89 (Fragment) OS=Mus musculus OX=10090 GN=Igkv12-89 PE=4 SV=4 0 10.687 24 2 9 1 112 12.1 7.85 2 2 140461.2813 126376.4531 102066.4063 20255.98047 1 1 1 1 response to stimulus "Pf00047, Pf07686" 384411 ENSMUSG00000076534.6 Igkv12-89 6 0 High Q8K182 Complement component C8 alpha chain OS=Mus musculus OX=10090 GN=C8a PE=1 SV=1 0 21.059 20 8 9 8 587 66 6.54 131267.5664 15242.08008 2 1 defense response;metabolic process;regulation of biological process;response to stimulus extracellular;membrane protein binding "Pf00057, Pf00090, Pf01823, Pf14008" 230558 ENSMUSG00000035031.15 C8a 4 Regulation of Complement cascade; Terminal pathway of complement Complement and coagulation cascades; Prion diseases; Systemic lupus erythematosus; Amoebiasis 0 High P49429 4-hydroxyphenylpyruvate dioxygenase OS=Mus musculus OX=10090 GN=Hpd PE=1 SV=3 0 16.228 18 5 9 5 393 45 7.06 3809.196777 11538.0459 1 1 metabolic process cytoplasm;endoplasmic reticulum;Golgi;membrane catalytic activity;metal ion binding "Pf00903, Pf12681, Pf13669" 15445 ENSMUSG00000029445.13 Hpd 5 Phenylalanine and tyrosine catabolism Ubiquinone and other terpenoid-quinone biosynthesis; Metabolic pathways; Phenylalanine metabolism; Tyrosine metabolism 0 High Q8BGL3 Sulfotransferase OS=Mus musculus OX=10090 GN=Sult2a8 PE=1 SV=1 0 15.599 23 6 9 6 282 33.3 7.02 catalytic activity "Pf00685, Pf13469" 76971 ENSMUSG00000030378.15 2810007J24Rik; Sult2a8 7 Cytosolic sulfonation of small molecules 0 High Q6NVF9 Cleavage and polyadenylation specificity factor subunit 6 OS=Mus musculus OX=10090 GN=Cpsf6 PE=1 SV=1 0 22.66 12 5 9 5 551 59.1 7.15 69708.0918 113182.27 6580.26709 2 3 1 cell organization and biogenesis;metabolic process membrane;nucleus RNA binding "Pf00076, Pf14259" 432508 ENSMUSG00000055531.12 Cpsf6 10 mRNA surveillance pathway 0 High O70200 Allograft inflammatory factor 1 OS=Mus musculus OX=10090 GN=Aif1 PE=1 SV=1 0 15.485 27 3 9 3 147 16.9 8.76 25817.72852 1 cell communication;cell organization and biogenesis;defense response;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;nucleus metal ion binding;protein binding Pf13499 11629 ENSMUSG00000024397.14 Aif1 17 0 High O55142 60S ribosomal protein L35a OS=Mus musculus OX=10090 GN=Rpl35a PE=1 SV=2 0.002 5.268 25 3 9 3 110 12.5 10.89 11106.24316 25086.9668 1 1 metabolic process membrane;mitochondrion;ribosome RNA binding;structural molecule activity Pf01247 100043423; 57808; 100042363; 100302576; 100040169; 100046034; 100048620 ENSMUSG00000060636.13 Rpl35a-ps4; Rpl35a; Rpl35a-ps2; Gm10243; Rpl35a-ps5; LOC100862595; Gm14279; LOC100048620 2; 16; 1; 6; 5 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q9CQN1 "Heat shock protein 75 kDa, mitochondrial OS=Mus musculus OX=10090 GN=Trap1 PE=1 SV=1" 0 13.747 8 4 9 3 706 80.2 6.68 74189.57959 14101.97656 40047.02588 2 1 2 metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion;organelle lumen nucleotide binding;protein binding;RNA binding "Pf00183, Pf02518, Pf13589" 68015 ENSMUSG00000005981.11 Trap1 16 0 High Q61235 Beta-2-syntrophin OS=Mus musculus OX=10090 GN=Sntb2 PE=1 SV=2 0 9.451 8 4 9 2 520 56.3 8.69 171794.3906 32482.3457 37786.62891 42118.32031 2 1 1 1 cytoplasm;cytoskeleton;membrane protein binding;RNA binding;structural molecule activity "Pf00169, Pf00595, Pf13180" 20650 ENSMUSG00000041308.6 Sntb2 8 0 High Q9DC51 Guanine nucleotide-binding protein G(i) subunit alpha OS=Mus musculus OX=10090 GN=Gnai3 PE=1 SV=3 0 12.637 16 5 9 1 354 40.5 5.69 cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;Golgi;membrane;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding;signal transducer activity "Pf00025, Pf00503" 14679 ENSMUSG00000000001.4 Gnai3 3 PLC beta mediated events; ADP signalling through P2Y purinoceptor 12; Adenylate cyclase inhibitory pathway; G-protein activation; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding Oxytocin signaling pathway; Leukocyte transendothelial migration; Morphine addiction; Cholinergic synapse; Chagas disease (American trypanosomiasis); Retrograde endocannabinoid signaling; Dopaminergic synapse; Progesterone-mediated oocyte maturation; GABAergic synapse; Regulation of lipolysis in adipocytes; Toxoplasmosis; Chemokine signaling pathway; Platelet activation; Melanogenesis; Axon guidance; Sphingolipid signaling pathway; Glutamatergic synapse; Pertussis; Parkinson's disease; Cocaine addiction; Long-term depression; cGMP-PKG signaling pathway; Rap1 signaling pathway; Pathways in cancer; Alcoholism; cAMP signaling pathway; Tight junction; Gastric acid secretion; Renin secretion; Gap junction; Circadian entrainment; Estrogen signaling pathway; Serotonergic synapse; Adrenergic signaling in cardiomyocytes 0 High P70168 Importin subunit beta-1 OS=Mus musculus OX=10090 GN=Kpnb1 PE=1 SV=2 0 8.435 4 4 9 4 876 97.1 4.78 1 1 288208.657 4633.655273 3 1 Acetyl [N-Term] cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;membrane;nucleus protein binding;RNA binding;transporter activity "Pf02985, Pf03810, Pf13513" 16211 ENSMUSG00000001440.5 Kpnb1 11 Activation of DNA fragmentation factor; Neutrophil degranulation; Regulation of cholesterol biosynthesis by SREBP (SREBF) RNA transport 0 High P27046 Alpha-mannosidase 2 OS=Mus musculus OX=10090 GN=Man2a1 PE=1 SV=2 0 26.959 11 8 9 8 1150 131.5 8.03 36323.13281 50485.61719 15176.70801 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process Golgi;membrane catalytic activity;metal ion binding "Pf01074, Pf03065, Pf07748, Pf09261" 17158 ENSMUSG00000024085.13 Man2a1 17 Reactions specific to the complex N-glycan synthesis pathway Metabolic pathways; N-Glycan biosynthesis 0 High Q9Z1A1 TFG protein OS=Mus musculus OX=10090 GN=Tfg PE=1 SV=1 0 8.392 16 3 9 3 397 43 5.1 39703.59766 32712.2207 39540.71094 75157.48438 1 1 1 1 cell organization and biogenesis;regulation of biological process;response to stimulus;transport membrane protein binding;signal transducer activity "Pf00564, Pf08232" 21787 ENSMUSG00000022757.18 Tfg 16 COPII (Coat Protein 2) Mediated Vesicle Transport 0 High Q91VK2 Eef1d protein OS=Mus musculus OX=10090 GN=Eef1d PE=1 SV=1 0 8.929 8 2 8 2 276 30.6 4.98 61367.51367 136175.8828 10258.48242 2 2 1 Met-loss+Acetyl [N-Term] metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;endoplasmic reticulum;nucleus DNA binding;protein binding;RNA binding;signal transducer activity Pf00736 66656 ENSMUSG00000055762.15 Eef1d 15 Eukaryotic Translation Elongation 0 High Q8CJG0 Protein argonaute-2 OS=Mus musculus OX=10090 GN=Ago2 PE=1 SV=3 0 10.854 7 5 8 5 860 97.2 9.19 14789.41797 27453.52734 14924.80664 2 1 1 cell differentiation;cell organization and biogenesis;development;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;DNA binding;metal ion binding;protein binding;RNA binding "Pf02170, Pf02171, Pf08699" 239528 ENSMUSG00000036698.10 Ago2; Eif2c2 15 MicroRNA (miRNA) biogenesis; Transcriptional regulation by small RNAs; Post-transcriptional silencing by small RNAs; Small interfering RNA (siRNA) biogenesis 0 High Q9D880 Mitochondrial import inner membrane translocase subunit TIM50 OS=Mus musculus OX=10090 GN=Timm50 PE=1 SV=1 0 11.954 9 3 8 3 353 39.8 8.13 1 1 20943.26563 148645.3311 147996.4258 66347.35547 1 2 2 2 cell organization and biogenesis;metabolic process;transport membrane;mitochondrion catalytic activity;protein binding Pf03031 66525 ENSMUSG00000003438.17 Timm50 7 0 High Q9WU79 "Proline dehydrogenase 1, mitochondrial OS=Mus musculus OX=10090 GN=Prodh PE=1 SV=2" 0 14.289 15 5 8 5 599 68 8.24 56603.04785 33993.38672 2 1 metabolic process membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding Pf01619 19125 ENSMUSG00000003526.11; ENSMUSG00000111321.1 Prodh 16; CHR_MG3833_MG4220_PATCH Proline catabolism Arginine and proline metabolism; Metabolic pathways 0 High G3UX35 Transcription activator BRG1 (Fragment) OS=Mus musculus OX=10090 GN=Smarca4 PE=1 SV=1 0 16.878 5 5 8 5 1267 143.5 8.56 102548.5292 55725.91797 72921.82813 2 1 1 cell organization and biogenesis;metabolic process catalytic activity;nucleotide binding;protein binding "Pf00176, Pf00270, Pf00271, Pf07529, Pf07533, Pf11496, Pf14619" ENSMUSG00000032187.16 9 0 High A2AN08 E3 ubiquitin-protein ligase UBR4 OS=Mus musculus OX=10090 GN=Ubr4 PE=1 SV=1 0 13.128 2 6 8 6 5180 571.9 6.06 35027.39063 46494.5127 16850.64355 2 2 2 metabolic process cytoplasm;cytoskeleton;cytosol;membrane;nucleus catalytic activity;metal ion binding;protein binding "Pf02207, Pf13764" 69116 ENSMUSG00000066036.14 Ubr4 4 Neutrophil degranulation Viral carcinogenesis 0 High Q8BRH0 Protein O-mannosyl-transferase TMTC3 OS=Mus musculus OX=10090 GN=Tmtc3 PE=1 SV=2 0 13.317 7 4 8 4 920 104.1 8.53 28781.81641 24875.09375 2 1 cell differentiation;regulation of biological process;response to stimulus endoplasmic reticulum;membrane protein binding "Pf00515, Pf07719, Pf08409, Pf12895, Pf13181, Pf13414, Pf13424, Pf13428, Pf13431, Pf13432, Pf14559" 237500 Tmtc3 10 0 High Q8VHM5 Heterogeneous nuclear ribonucleoprotein R OS=Mus musculus OX=10090 GN=Hnrnpr PE=1 SV=1 0 5.378 4 3 8 3 632 70.8 8.13 14345.66895 37959.51611 19506.03516 48626.59473 2 2 1 3 regulation of biological process cytoplasm;nucleus;spliceosomal complex RNA binding "Pf00076, Pf13893, Pf14259" 74326 ENSMUSG00000066037.14 Hnrnpr 4 mRNA Splicing - Major Pathway 0 High E9Q3C1 C2 domain-containing protein 2 OS=Mus musculus OX=10090 GN=C2cd2 PE=1 SV=1 0 10.887 10 4 8 4 696 76.5 7.72 7626.62207 1 cytosol;membrane;nucleus 207781 ENSMUSG00000045975.7 C2cd2 16 0 High A0A498WGK2 Asparaginyl-tRNA synthetase OS=Mus musculus OX=10090 GN=Nars PE=4 SV=1 0 13.434 15 6 8 6 558 64.2 5.86 62082.03516 82426.84375 15192.32324 1 1 2 0 High A0A286YDB7 Translocon-associated protein subunit alpha (Fragment) OS=Mus musculus OX=10090 GN=Ssr1 PE=1 SV=1 0.002 4.893 20 2 8 2 115 13.1 3.81 3130.79834 84524.32031 16167.24829 1 1 2 0 High P50171 Estradiol 17-beta-dehydrogenase 8 OS=Mus musculus OX=10090 GN=Hsd17b8 PE=1 SV=2 0 17.252 26 4 8 4 259 26.6 6.54 1 2 586059.9922 470809.1719 203407.4961 4 3 3 cell organization and biogenesis;metabolic process membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf00106, Pf08659, Pf13561" 14979 ENSMUSG00000073422.10 H2-Ke6 17 Fatty acyl-CoA biosynthesis Steroid hormone biosynthesis; Metabolic pathways 0 High Q9WUA2 Phenylalanine--tRNA ligase beta subunit OS=Mus musculus OX=10090 GN=Farsb PE=1 SV=2 0 10.161 7 4 8 4 589 65.7 7.12 19343.24512 3410.765625 2 1 cell organization and biogenesis;metabolic process cytoplasm;membrane catalytic activity;metal ion binding;nucleotide binding;RNA binding "Pf03483, Pf03484" 23874 ENSMUSG00000026245.16 Farsb 1 Aminoacyl-tRNA biosynthesis 0 High P52480 Pyruvate kinase PKM OS=Mus musculus OX=10090 GN=Pkm PE=1 SV=4 0 11.896 11 5 8 5 531 57.8 7.47 73522.34692 118659.9131 78279.07129 125575.5371 4 4 3 4 cell death;cell organization and biogenesis;metabolic process;response to stimulus cytoplasm;cytosol;mitochondrion;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding;RNA binding "Pf00224, Pf02887" 18746 ENSMUSG00000032294.17 Pkm 9 Neutrophil degranulation; Glycolysis Pyruvate metabolism; Type II diabetes mellitus; Metabolic pathways; Biosynthesis of amino acids; Purine metabolism; Glycolysis / Gluconeogenesis; Carbon metabolism; Central carbon metabolism in cancer; Glucagon signaling pathway; Viral carcinogenesis 0 High Q64310 Surfeit locus protein 4 OS=Mus musculus OX=10090 GN=Surf4 PE=1 SV=1 0 12.414 16 3 8 3 269 30.4 7.78 15188.48633 1 Met-loss [N-Term] cell organization and biogenesis;regulation of biological process endoplasmic reticulum;Golgi;membrane protein binding Pf02077 20932 ENSMUSG00000014867.9 Surf4 2 COPI-dependent Golgi-to-ER retrograde traffic; Neutrophil degranulation 0 High Q8CFX1 GDH/6PGL endoplasmic bifunctional protein OS=Mus musculus OX=10090 GN=H6pd PE=1 SV=2 0 11.199 6 4 8 4 789 88.9 6.93 10938.25098 3536.772949 41420.76953 1 1 1 metabolic process cytoplasm;endoplasmic reticulum;mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf00479, Pf01182, Pf02781" 100198 ENSMUSG00000028980.14 H6pd 4 Metabolic pathways; Pentose phosphate pathway; Carbon metabolism 0 High Q9D8V0 Minor histocompatibility antigen H13 OS=Mus musculus OX=10090 GN=Hm13 PE=1 SV=1 0 13.802 12 2 8 1 378 41.7 6.04 39537.98438 1 metabolic process cell surface;endoplasmic reticulum;membrane catalytic activity;protein binding "Pf04258, Pf06550" 14950 ENSMUSG00000019188.16 H13 2 0 High G3UZ34 116 kDa U5 small nuclear ribonucleoprotein component OS=Mus musculus OX=10090 GN=Eftud2 PE=1 SV=1 0 17.358 11 7 8 6 962 108.3 5.02 50027.65137 125198.5117 54996.58594 39220.62012 3 2 1 3 catalytic activity;nucleotide binding "Pf00009, Pf00679, Pf03144, Pf03764, Pf14492" ENSMUSG00000020929.14 11 0 High P57016 Ladinin-1 OS=Mus musculus OX=10090 GN=Lad1 PE=1 SV=1 0 19.043 16 6 8 6 528 58.8 9.73 26215.18555 1 extracellular protein binding;structural molecule activity 16763 ENSMUSG00000041782.14 Lad1 1 0 High Q00623 Apolipoprotein A-I OS=Mus musculus OX=10090 GN=Apoa1 PE=1 SV=2 0 7.405 13 3 8 3 264 30.6 5.73 1 1 62304.23242 153143.4648 13297.59473 26403.13721 3 2 1 2 cell organization and biogenesis;cell proliferation;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytosol;extracellular;nucleus enzyme regulator activity;protein binding;transporter activity Pf01442 11806 ENSMUSG00000032083.8 Apoa1 9 Post-translational protein phosphorylation; Scavenging by Class A Receptors; Chylomicron assembly; Signaling by GPCR; ABC transporters in lipid homeostasis; HDL clearance; Chylomicron remodeling; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Scavenging by Class B Receptors; HDL assembly; Retinoid metabolism and transport; Platelet degranulation ; HDL remodeling; Scavenging of heme from plasma Vitamin digestion and absorption; PPAR signaling pathway; African trypanosomiasis; Fat digestion and absorption 0 High Q6PDN3 "Myosin light chain kinase, smooth muscle OS=Mus musculus OX=10090 GN=Mylk PE=1 SV=3" 0 17.089 4 6 8 6 1941 212.8 6.25 16546.45532 56179.38477 12943.58301 2 2 2 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00041, Pf00047, Pf00069, Pf07679, Pf07714, Pf13895, Pf13927" 107589 Mylk 16 0 High Q8VBT2 L-serine dehydratase/L-threonine deaminase OS=Mus musculus OX=10090 GN=Sds PE=1 SV=3 0 14.363 20 4 8 4 327 34.6 7.12 129237.3984 1 Met-loss+Acetyl [N-Term] metabolic process cytoplasm;cytosol;mitochondrion catalytic activity;protein binding Pf00291 231691 ENSMUSG00000029597.14 Sds 5 "Metabolic pathways; Biosynthesis of amino acids; Cysteine and methionine metabolism; Glycine, serine and threonine metabolism; Valine, leucine and isoleucine biosynthesis; Carbon metabolism" 0 High Q78IK2 "ATP synthase membrane subunit DAPIT, mitochondrial OS=Mus musculus OX=10090 GN=Atp5md PE=1 SV=1" 0 8.033 29 2 8 2 58 6.4 9.83 25940.50391 10929.34082 57557.26563 1 1 1 Met-loss [N-Term] membrane;mitochondrion Pf14960 66477; 102642507 ENSMUSG00000071528.3 Usmg5; LOC100504912; LOC102642507 19; 4 0 High O54825 Bystin OS=Mus musculus OX=10090 GN=Bysl PE=1 SV=3 0 13.541 8 3 8 3 436 49.8 7.78 1823462.328 2646241.375 2155280.75 2077729.583 1 1 1 1 cell differentiation;cell proliferation;metabolic process cytoplasm;membrane;nucleus RNA binding Pf05291 53414 ENSMUSG00000023988.8 Bysl 17 0 High P25911 Tyrosine-protein kinase Lyn OS=Mus musculus OX=10090 GN=Lyn PE=1 SV=4 0 14.065 9 4 8 3 512 58.8 7.15 7243015.494 4366533.5 1300271 858015.6836 3 1 1 2 cell communication;cell differentiation;cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;Golgi;membrane;nucleus;vacuole catalytic activity;nucleotide binding;protein binding "Pf00017, Pf00018, Pf00069, Pf07653, Pf07714, Pf14604" 17096 ENSMUSG00000042228.14 Lyn 4 Cell surface interactions at the vascular wall; FCERI mediated NF-kB activation; Role of LAT2/NTAL/LAB on calcium mobilization; CD28 co-stimulation; CTLA4 inhibitory signaling; FCGR activation; Cyclin D associated events in G1; CD209 (DC-SIGN) signaling; Platelet Adhesion to exposed collagen; FCERI mediated Ca+2 mobilization; GPVI-mediated activation cascade; Regulation of KIT signaling; EPHB-mediated forward signaling; FCERI mediated MAPK activation; EPHA-mediated growth cone collapse; CD22 mediated BCR regulation; Growth hormone receptor signaling; EPH-ephrin mediated repulsion of cells Epstein-Barr virus infection; Chemokine signaling pathway; Platelet activation; B cell receptor signaling pathway; Fc gamma R-mediated phagocytosis; Long-term depression; NF-kappa B signaling pathway; Fc epsilon RI signaling pathway; Viral carcinogenesis 1 High P80317 T-complex protein 1 subunit zeta OS=Mus musculus OX=10090 GN=Cct6a PE=1 SV=3 0 13.243 16 5 8 5 531 58 7.08 10934.55103 21393.53125 6564.677734 2 1 1 metabolic process;regulation of biological process;transport cytoplasm;cytosol;membrane nucleotide binding;protein binding;RNA binding "Pf00118, Pf05504" 12466 Cct6a 5 0 High A2AFQ2 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Mus musculus OX=10090 GN=Hsd17b10 PE=1 SV=1 0 15.146 36 5 8 5 271 28.4 8.76 2 2 167704.2988 50978.91309 42324.26953 35232.54297 3 2 1 1 cell organization and biogenesis;metabolic process endoplasmic reticulum;membrane;mitochondrion catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00106, Pf08659, Pf13561" 15108 ENSMUSG00000025260.10 Hsd17b10 X Branched-chain amino acid catabolism 0 High P52430 Serum paraoxonase/arylesterase 1 OS=Mus musculus OX=10090 GN=Pon1 PE=1 SV=2 0 15.178 29 6 8 1 355 39.5 5.22 476529.3223 227038.5781 22398.48633 193481.2998 2 1 1 2 metabolic process;regulation of biological process;response to stimulus extracellular catalytic activity;metal ion binding;protein binding "Pf01731, Pf03088, Pf08450" 18979 ENSMUSG00000002588.12 Pon1 6 Synthesis of 5-eicosatetraenoic acids Metabolic pathways 5 High P97450 "ATP synthase-coupling factor 6, mitochondrial OS=Mus musculus OX=10090 GN=Atp5pf PE=1 SV=1" 0 6.387 22 2 8 2 108 12.5 9.36 6987.58252 9011.619141 1 1 metabolic process;transport membrane;mitochondrion catalytic activity;transporter activity Pf05511 11957 ENSMUSG00000022890.13 Atp5j 16 Cristae formation; Formation of ATP by chemiosmotic coupling Metabolic pathways; Huntington's disease; Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High Q07797 Galectin-3-binding protein OS=Mus musculus OX=10090 GN=Lgals3bp PE=1 SV=1 0 15.408 10 3 8 3 577 64.5 5.14 23322.51367 10629.29492 1 1 transport extracellular;membrane protein binding;receptor activity "Pf00530, Pf07707" 19039 ENSMUSG00000033880.11 Lgals3bp 11 Platelet degranulation 0 High O88967 ATP-dependent zinc metalloprotease YME1L1 OS=Mus musculus OX=10090 GN=Yme1l1 PE=1 SV=1 0 11.141 8 4 8 4 715 80 8.97 35393.26172 58427.53125 88819.86719 2 1 4 cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding "Pf00004, Pf01078, Pf01434, Pf05496, Pf06068, Pf07724, Pf07728, Pf13191, Pf13207, Pf13401, Pf13481" 27377 ENSMUSG00000026775.9 Yme1l1 2 Processing of SMDT1 0 High O54833 Casein kinase II subunit alpha' OS=Mus musculus OX=10090 GN=Csnk2a2 PE=1 SV=1 0 16.094 23 6 8 6 350 41.2 8.56 16100.97852 44908.89453 111504.1016 18574.01172 1 1 1 1 cell death;metabolic process;regulation of biological process;response to stimulus chromosome;cytoplasm;membrane;nucleus catalytic activity;nucleotide binding;protein binding "Pf00069, Pf01636, Pf07714" 13000 ENSMUSG00000046707.9 Csnk2a2 8 WNT mediated activation of DVL; Regulation of TP53 Activity through Phosphorylation; Synthesis of PC; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Condensation of Prometaphase Chromosomes; Receptor Mediated Mitophagy; Regulation of PTEN stability and activity; Signal transduction by L1; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Herpes simplex infection; Wnt signaling pathway; Epstein-Barr virus infection; Adherens junction; Ribosome biogenesis in eukaryotes; NF-kappa B signaling pathway; Tight junction; Measles 0 High O54941 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Mus musculus OX=10090 GN=Smarce1 PE=1 SV=1 0 12.162 11 4 8 4 411 46.6 4.88 48775.38232 8389.375977 2 1 cell differentiation;cell organization and biogenesis;regulation of biological process nucleus catalytic activity;DNA binding;protein binding;RNA binding Pf00505 57376 ENSMUSG00000037935.16 Smarce1 11 RMTs methylate histone arginines; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 0 High A0A2I3BPW0 Protein NDRG2 (Fragment) OS=Mus musculus OX=10090 GN=Ndrg2 PE=1 SV=1 0 14.242 26 4 8 4 273 30.5 5.11 105002.0117 2 Met-loss+Acetyl [N-Term] 0 High Q8R010 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 OS=Mus musculus OX=10090 GN=Aimp2 PE=1 SV=2 0 10.68 8 1 8 1 320 35.4 7.83 12468.64844 343806 1 1 cell death;cell differentiation;cell organization and biogenesis;development;metabolic process;regulation of biological process cytoplasm;cytosol;membrane;nucleus protein binding;structural molecule activity "Pf00043, Pf13410, Pf14497" 231872 ENSMUSG00000029610.13 Aimp2 5 0 High P61750 ADP-ribosylation factor 4 OS=Mus musculus OX=10090 GN=Arf4 PE=1 SV=2 0 10.93 41 5 8 3 180 20.4 7.14 42031.21484 28241.64648 1 1 cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;Golgi;membrane catalytic activity;nucleotide binding;protein binding;signal transducer activity "Pf00025, Pf00071, Pf00503, Pf04670, Pf08477, Pf09439" 11843 ENSMUSG00000021877.11 Arf4 14 VxPx cargo-targeting to cilium; COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic 2 High Q8VCD5 Mediator of RNA polymerase II transcription subunit 17 OS=Mus musculus OX=10090 GN=Med17 PE=1 SV=1 0 6.912 4 3 8 3 649 72.4 7.3 18920.88672 21125.16211 48048.85547 12031.37109 1 1 1 1 metabolic process;regulation of biological process;response to stimulus membrane;nucleus catalytic activity;protein binding;receptor activity Pf10156 234959 ENSMUSG00000031935.9 Med17 9 Generic Transcription Pathway; Mus musculus biological processes; Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes Thyroid hormone signaling pathway 0 High P61205 ADP-ribosylation factor 3 OS=Mus musculus OX=10090 GN=Arf3 PE=2 SV=2 0 13.066 35 4 8 2 181 20.6 7.43 7589.027832 45223.77734 1 1 regulation of biological process;response to stimulus;transport cytoplasm;Golgi catalytic activity;nucleotide binding;protein binding;signal transducer activity "Pf00025, Pf00071, Pf00503, Pf01926, Pf04670, Pf08477, Pf09439" 11842 ENSMUSG00000051853.9 Arf3 15 Synthesis of PIPs at the Golgi membrane Endocytosis 0 High Q8CGB6 Tensin-2 OS=Mus musculus OX=10090 GN=Tns2 PE=1 SV=1 0 11.939 4 4 8 4 1400 151.9 8.48 95010.53735 25992.6582 3 1 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus membrane catalytic activity;metal ion binding;protein binding;receptor activity;signal transducer activity "Pf00017, Pf00130, Pf03154, Pf05109, Pf08416, Pf09770, Pf10409, Pf13388" 209039 ENSMUSG00000037003.15 Tenc1; Tns2 15 0 High E9PWY9 Phenylalanine--tRNA ligase alpha subunit OS=Mus musculus OX=10090 GN=Farsa PE=1 SV=1 0 6.253 5 2 8 2 507 57.4 8.02 99805.40625 2524.35791 5098.344238 1 1 1 Met-loss+Acetyl [N-Term] metabolic process cytoplasm catalytic activity;nucleotide binding;RNA binding "Pf00152, Pf01409, Pf08279" ENSMUSG00000003808.18 8 0 High A0A075B5S5 Immunoglobulin heavy variable 7-4 OS=Mus musculus OX=10090 GN=Ighv7-4 PE=4 SV=1 0 10.863 23 2 8 2 120 13.4 8.9 76083.59961 24205.80908 3 2 ENSMUSG00000076668.4 12 0 High O89017 Legumain OS=Mus musculus OX=10090 GN=Lgmn PE=1 SV=1 0 7.559 9 3 8 3 435 49.3 6.39 53616.46875 12394.16504 1 1 metabolic process;regulation of biological process;response to stimulus endosome;vacuole catalytic activity Pf01650 19141 ENSMUSG00000021190.14 Lgmn 12 MHC class II antigen presentation; Vitamin D (calciferol) metabolism; Trafficking and processing of endosomal TLR Lysosome; Antigen processing and presentation 0 High Q60900 ELAV-like protein 3 OS=Mus musculus OX=10090 GN=Elavl3 PE=1 SV=1 0 6.68 8 3 8 1 367 39.5 9.28 cell differentiation;development RNA binding "Pf00076, Pf13893, Pf14259" 15571 ENSMUSG00000003410.8 Elavl3 9 0 High Q61233 Plastin-2 OS=Mus musculus OX=10090 GN=Lcp1 PE=1 SV=4 0 8.088 7 4 8 4 627 70.1 5.33 95012.24023 37924.84375 2 1 cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane metal ion binding;protein binding "Pf00036, Pf00307, Pf13405, Pf13499, Pf13833" 18826 ENSMUSG00000021998.16 Lcp1 14 0 High A0A0A0MQ76 Nucleolar protein 58 OS=Mus musculus OX=10090 GN=Nop58 PE=1 SV=1 0 15.253 16 5 8 5 444 50 9.42 17622.95313 1 "Pf01798, Pf08060, Pf08156" ENSMUSG00000026020.9 1 0 High A0A1Y7VNF4 ERO1-like beta (S. cerevisiae) OS=Mus musculus OX=10090 GN=Ero1lb PE=1 SV=1 0 19.584 15 6 8 6 493 55.9 7.8 12249.62305 5168.290527 89177.69336 2 1 2 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;transport endoplasmic reticulum;membrane catalytic activity Pf04137 67475 Ero1lb 13 0 High P11087 Collagen alpha-1(I) chain OS=Mus musculus OX=10090 GN=Col1a1 PE=1 SV=4 0 8.866 5 5 8 5 1453 137.9 5.85 5 1 6 2 1797216.906 2207735.813 516797.5488 305657.9063 5 4 4 3 cell communication;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;extracellular;Golgi metal ion binding;protein binding;structural molecule activity "Pf00093, Pf01391, Pf01410" 12842 ENSMUSG00000001506.10 Col1a1 11 Anchoring fibril formation; ECM proteoglycans; Cell surface interactions at the vascular wall; Platelet Aggregation (Plug Formation); Integrin cell surface interactions; Collagen degradation; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; Crosslinking of collagen fibrils; Collagen chain trimerization; GP1b-IX-V activation signalling; Platelet Adhesion to exposed collagen; MET activates PTK2 signaling; GPVI-mediated activation cascade; Non-integrin membrane-ECM interactions AGE-RAGE signaling pathway in diabetic complications; Focal adhesion; Protein digestion and absorption; Platelet activation; Proteoglycans in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway; Amoebiasis 0 High Q9D1I6 "39S ribosomal protein L14, mitochondrial OS=Mus musculus OX=10090 GN=Mrpl14 PE=1 SV=1" 0.003 3.672 12 2 8 2 145 15.9 10.99 metabolic process mitochondrion;ribosome RNA binding;structural molecule activity Pf00238 68463 ENSMUSG00000023939.7 Mrpl14 17 Mitochondrial translation termination; Mitochondrial translation elongation Ribosome 0 High P62315 Small nuclear ribonucleoprotein Sm D1 OS=Mus musculus OX=10090 GN=Snrpd1 PE=1 SV=1 0 7.886 28 2 8 2 119 13.3 11.56 4944.699707 281590.9453 11054.94238 52204.57031 1 2 1 2 cell organization and biogenesis;metabolic process cytoplasm;cytosol;nucleus;spliceosomal complex RNA binding Pf01423 20641 ENSMUSG00000002477.4 Snrpd1 18 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; snRNP Assembly Spliceosome; Systemic lupus erythematosus 0 High Q9DBM1 G patch domain-containing protein 1 OS=Mus musculus OX=10090 GN=Gpatch1 PE=2 SV=1 0.004 2.682 1 1 8 1 930 102.9 6.98 61706.71094 76816.6875 69014.27344 118221.6484 1 1 1 1 metabolic process spliceosomal complex "Pf01585, Pf07713" 67471 ENSMUSG00000063808.14 Gpatch1 7 0 High Q8BGT5 Alanine aminotransferase 2 OS=Mus musculus OX=10090 GN=Gpt2 PE=1 SV=1 0 11.946 13 4 8 4 522 57.9 8 19370.28809 20584.41699 2 2 metabolic process mitochondrion catalytic activity Pf00155 108682 ENSMUSG00000031700.11 Gpt2 8 Amino acid synthesis and interconversion (transamination) "Metabolic pathways; Biosynthesis of amino acids; 2-Oxocarboxylic acid metabolism; Carbon metabolism; Alanine, aspartate and glutamate metabolism; Arginine biosynthesis" 0 High G3UX26 Voltage-dependent anion-selective channel protein 2 OS=Mus musculus OX=10090 GN=Vdac2 PE=1 SV=1 0 8.546 11 2 8 2 283 30.4 7.58 1 1 98453.91016 286515.625 233155.0938 2 2 2 transport membrane transporter activity Pf01459 ENSMUSG00000021771.13 14 0 High P58022 Lysyl oxidase homolog 2 OS=Mus musculus OX=10090 GN=Loxl2 PE=1 SV=2 0 10.126 5 2 8 2 776 86.9 6.57 23112.9043 1 cell organization and biogenesis;cell proliferation;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport chromosome;extracellular;membrane;nucleus catalytic activity;metal ion binding;protein binding;receptor activity "Pf00530, Pf01186" 94352 ENSMUSG00000034205.16 Loxl2 14 0 High P11031 Activated RNA polymerase II transcriptional coactivator p15 OS=Mus musculus OX=10090 GN=Sub1 PE=1 SV=3 0 5.76 16 2 8 2 127 14.4 9.6 67311.91895 71669.70313 9855.15625 30368.55469 2 2 1 2 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus nucleus catalytic activity;DNA binding;protein binding;RNA binding Pf02229 20024 ENSMUSG00000022205.15 Sub1 15 0 High Q8BGH2 Sorting and assembly machinery component 50 homolog OS=Mus musculus OX=10090 GN=Samm50 PE=1 SV=1 0 8.627 9 4 7 4 469 51.8 6.8 96899.08691 151329.4238 103042.3828 213007.3125 3 3 3 3 cell organization and biogenesis;transport cytoplasm;membrane;mitochondrion protein binding "Pf01103, Pf07244" 68653 ENSMUSG00000022437.6 Samm50 15 0 High G3UY72 Alpha-aminoadipic semialdehyde dehydrogenase (Fragment) OS=Mus musculus OX=10090 GN=Aldh7a1 PE=1 SV=1 0 8.537 14 3 7 3 321 35.1 8.28 24074.77612 7843.506348 3 1 metabolic process catalytic activity Pf00171 ENSMUSG00000053644.13 18 0 High P16332 "Methylmalonyl-CoA mutase, mitochondrial OS=Mus musculus OX=10090 GN=Mmut PE=1 SV=2" 0 11.905 7 3 7 3 748 82.8 6.89 166944.9883 148369.0762 13284.9668 81868.79688 3 3 1 3 metabolic process mitochondrion;organelle lumen catalytic activity;metal ion binding "Pf01642, Pf02310" 17850 ENSMUSG00000023921.8 Mut 17 "Propionyl-CoA catabolism; Cobalamin (Cbl, vitamin B12) transport and metabolism" "Valine, leucine and isoleucine degradation; Metabolic pathways; Propanoate metabolism; Carbon metabolism; Glyoxylate and dicarboxylate metabolism" 0 High Q8QZR5 Alanine aminotransferase 1 OS=Mus musculus OX=10090 GN=Gpt PE=1 SV=3 0 7.961 8 3 7 3 496 55.1 6.64 13336.99365 10094.96143 2 2 metabolic process cytoplasm catalytic activity Pf00155 76282 ENSMUSG00000022546.4 Gpt 15 Amino acid synthesis and interconversion (transamination) "Metabolic pathways; Biosynthesis of amino acids; 2-Oxocarboxylic acid metabolism; Carbon metabolism; Alanine, aspartate and glutamate metabolism; Arginine biosynthesis" 0 High P12815 Programmed cell death protein 6 OS=Mus musculus OX=10090 GN=Pdcd6 PE=1 SV=2 0 8.176 9 2 7 2 191 21.9 5.4 5872.527344 2727.588379 1 1 cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;endosome;membrane;nucleus catalytic activity;metal ion binding;protein binding "Pf00036, Pf13405, Pf13499, Pf13833" 18570 ENSMUSG00000021576.5 Pdcd6 13 0 High A0A075B5Q5 Immunoglobulin heavy variable 2-9 (Fragment) OS=Mus musculus OX=10090 GN=Ighv2-9 PE=4 SV=1 0.002 5.216 14 1 7 1 116 12.5 8.16 1 2 475144.625 8482.583008 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000096638.2 LOC674142 12 0 High Q8BHY2 Nucleolar complex protein 4 homolog OS=Mus musculus OX=10090 GN=Noc4l PE=2 SV=1 0.002 4.922 4 2 7 2 516 58.6 6.77 metabolic process membrane;nucleus RNA binding Pf03914 100608 ENSMUSG00000033294.11 Noc4l 5 Major pathway of rRNA processing in the nucleolus and cytosol 0 High Q8BH00 2-aminomuconic semialdehyde dehydrogenase OS=Mus musculus OX=10090 GN=Aldh8a1 PE=1 SV=1 0 11.796 11 3 7 3 487 53.6 7.55 39315.40259 170032.1094 27020.83594 3 1 1 metabolic process cytoplasm catalytic activity Pf00171 237320 ENSMUSG00000037542.13 Aldh8a1 10 RA biosynthesis pathway 0 High Q8BHN3 Neutral alpha-glucosidase AB OS=Mus musculus OX=10090 GN=Ganab PE=1 SV=1 0 12.754 7 5 7 5 944 106.8 6.06 134854.1094 4 metabolic process endoplasmic reticulum;Golgi;membrane catalytic activity;protein binding;RNA binding "Pf01055, Pf13802" 14376 Ganab 19 Calnexin/calreticulin cycle Metabolic pathways; N-Glycan biosynthesis; Protein processing in endoplasmic reticulum 0 High Q3U0S6 Ras-interacting protein 1 OS=Mus musculus OX=10090 GN=Rasip1 PE=1 SV=3 0 24.432 12 6 7 6 961 103.5 7.83 58085.75977 85384.35938 87302.88867 18237.11328 2 1 2 2 cell differentiation;regulation of biological process;response to stimulus cytoplasm;Golgi protein binding "Pf00788, Pf01843" 69903 ENSMUSG00000044562.12 Rasip1 7 0 High P06909 Complement factor H OS=Mus musculus OX=10090 GN=Cfh PE=1 SV=2 0 11.931 8 7 7 7 1234 139 6.99 45894.63623 27936.84473 6437.474609 3 2 1 defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;extracellular;membrane;nucleus protein binding Pf00084 12628 ENSMUSG00000026365.15 Cfh 1 Regulation of Complement cascade Staphylococcus aureus infection; Complement and coagulation cascades 0 High Q64726 Zinc-alpha-2-glycoprotein OS=Mus musculus OX=10090 GN=Azgp1 PE=1 SV=2 0 15.38 18 4 7 4 307 35.3 6.18 17330.44336 6872.789551 1 1 regulation of biological process;response to stimulus extracellular;membrane;nucleus "Pf00129, Pf07654" 12007 ENSMUSG00000037053.6 Azgp1 5 Miscellaneous transport and binding events 0 High P29699 Alpha-2-HS-glycoprotein OS=Mus musculus OX=10090 GN=Ahsg PE=1 SV=1 0 22.315 30 5 7 5 345 37.3 6.51 82960.95654 20431.62305 40674.56641 3 1 1 cell organization and biogenesis;defense response;regulation of biological process;response to stimulus extracellular;Golgi enzyme regulator activity Pf00031 11625 ENSMUSG00000022868.5 Ahsg 16 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Platelet degranulation ; Neutrophil degranulation; Post-translational protein phosphorylation 0 High Q9D0S9 "Histidine triad nucleotide-binding protein 2, mitochondrial OS=Mus musculus OX=10090 GN=Hint2 PE=1 SV=1" 0 21.703 40 4 7 4 163 17.3 9.82 cell death;metabolic process;regulation of biological process mitochondrion catalytic activity;nucleotide binding "Pf01230, Pf11969" 68917 ENSMUSG00000028470.10 Hint2 4 0 High A2AP82 Transcription initiation factor TFIID subunit 9B OS=Mus musculus OX=10090 GN=Taf9b PE=1 SV=1 0.003 3.662 4 1 7 1 293 32 5.43 29059118.72 28668161.08 17055477.91 19905367.21 2 2 2 2 cell organization and biogenesis;metabolic process;regulation of biological process nucleus catalytic activity;DNA binding;protein binding "Pf02291, Pf15630" 407786 ENSMUSG00000047242.14 Taf9b X 0 High Q9JKX3 Transferrin receptor protein 2 OS=Mus musculus OX=10090 GN=Tfr2 PE=1 SV=2 0 14.366 8 6 7 6 798 88.3 6.13 2641.54248 1 cellular homeostasis;defense response;regulation of biological process;response to stimulus;transport cytoplasm;membrane protein binding;receptor activity "Pf02225, Pf04253, Pf04389" 50765 ENSMUSG00000029716.13 Tfr2 5 Transferrin endocytosis and recycling 0 High Q8K426 Resistin-like gamma OS=Mus musculus OX=10090 GN=Retnlg PE=1 SV=1 0 15.041 38 3 7 3 117 12.5 7.39 114542.187 2 cellular component movement;regulation of biological process;response to stimulus extracellular protein binding Pf06954 245195 ENSMUSG00000022651.5 Retnlg 16 0 High Q9JKX6 ADP-sugar pyrophosphatase OS=Mus musculus OX=10090 GN=Nudt5 PE=1 SV=1 0 11.031 17 3 7 3 218 24 5.48 5341.293945 3042.801514 23307.48828 1 1 2 cell organization and biogenesis;metabolic process nucleus catalytic activity;metal ion binding;protein binding;RNA binding Pf00293 53893 ENSMUSG00000025817.12 Nudt5 2 Phosphate bond hydrolysis by NUDT proteins Purine metabolism 0 High H7BX99 Prothrombin OS=Mus musculus OX=10090 GN=F2 PE=1 SV=1 0 10.808 12 5 7 5 617 70.2 6.43 coagulation;defense response;metabolic process;regulation of biological process;response to stimulus extracellular catalytic activity;metal ion binding "Pf00051, Pf00089, Pf00594, Pf09342, Pf09396" ENSMUSG00000027249.15 2 0 High F8VPU2 "FERM, ARHGEF and pleckstrin domain-containing protein 1 OS=Mus musculus OX=10090 GN=Farp1 PE=1 SV=1" 0 11.673 6 5 7 5 1048 118.8 7.88 269429.9248 168697.5156 85304.69531 57751.73438 3 1 1 1 Met-loss+Acetyl [N-Term] cell organization and biogenesis;development;regulation of biological process cytoplasm;cytoskeleton;cytosol;membrane protein binding "Pf00169, Pf00373, Pf00621, Pf08736, Pf09379, Pf09380" 223254 ENSMUSG00000025555.14 Farp1 14 0 High Q6ZWQ7 Signal peptidase complex subunit 3 OS=Mus musculus OX=10090 GN=Spcs3 PE=1 SV=1 0 7.966 18 3 7 3 180 20.3 8.62 189510.7109 2 metabolic process endoplasmic reticulum;membrane catalytic activity Pf04573 76687 ENSMUSG00000054408.9 Spcs3 8 "Synthesis, secretion, and deacylation of Ghrelin" Protein export 0 High O89079 Coatomer subunit epsilon OS=Mus musculus OX=10090 GN=Cope PE=1 SV=3 0 11.564 24 4 7 4 308 34.5 5.06 34913.78125 1 Met-loss [N-Term] transport cytoplasm;Golgi;membrane protein binding;structural molecule activity Pf04733 59042 ENSMUSG00000055681.14 Cope 8 COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic 0 High Q3UZG4 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Mus musculus OX=10090 GN=Aimp1 PE=1 SV=1 0 11.173 20 4 7 4 319 35.1 8.57 22999.38086 47201.01563 60635.54102 1 1 2 cell communication;cell death;cellular component movement;defense response;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;cytosol;endoplasmic reticulum;extracellular;Golgi;membrane;nucleus protein binding;RNA binding Pf01588 13722 ENSMUSG00000028029.10 Aimp1 3 0 High P97479 Unconventional myosin-VIIa OS=Mus musculus OX=10090 GN=Myo7a PE=1 SV=2 0 14.242 4 6 7 6 2215 254.8 8.54 cell differentiation;cell organization and biogenesis;cellular component movement;transport cytoplasm;cytoskeleton;cytosol;membrane catalytic activity;motor activity;nucleotide binding;protein binding "Pf00063, Pf00373, Pf00612, Pf00784" 17921 ENSMUSG00000030761.15 Myo7a 7 The canonical retinoid cycle in rods (twilight vision); Signaling by GPCR 0 High Q61503 5'-nucleotidase OS=Mus musculus OX=10090 GN=Nt5e PE=1 SV=2 0 11.264 12 6 7 6 576 63.8 6.64 33082.95313 2 metabolic process;regulation of biological process cell surface;cytosol;membrane catalytic activity;metal ion binding;nucleotide binding "Pf00149, Pf02872, Pf09587" 23959 ENSMUSG00000032420.8 Nt5e 9 Nicotinate metabolism; Purine catabolism; Pyrimidine catabolism Metabolic pathways; Nicotinate and nicotinamide metabolism; Purine metabolism; Pyrimidine metabolism 0 High Q62009 Periostin OS=Mus musculus OX=10090 GN=Postn PE=1 SV=2 0 11.111 12 6 7 6 838 93.1 7.53 2 5 2 5 848019.7813 622299.7813 453625.3633 70629.62109 4 3 2 2 cell communication;cell growth;cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;extracellular;Golgi metal ion binding;protein binding "Pf02469, Pf07546" 50706 ENSMUSG00000027750.16 Postn 3 0 High E0CXS8 Predicted gene 8113 OS=Mus musculus OX=10090 GN=Gm8113 PE=4 SV=1 0.002 4.537 2 2 7 2 587 66 8.78 membrane ENSMUSG00000089901.1 14 0 Medium G3UYC6 Synaptotagmin-like protein 4 (Fragment) OS=Mus musculus OX=10090 GN=Sytl4 PE=1 SV=8 0.035 1.464 5 1 7 1 185 21.6 9.07 4091361.5 3033614 5377768.25 3961605.375 1 1 1 1 regulation of biological process;transport protein binding Pf02318 ENSMUSG00000031255.14 X 0 High Q61137 Astrotactin-1 OS=Mus musculus OX=10090 GN=Astn1 PE=1 SV=4 0 14.385 7 6 7 6 1302 144.8 5.21 44510.11523 1731260.25 65904.71875 2 1 1 cellular component movement;response to stimulus endosome;membrane protein binding Pf14670 11899 ENSMUSG00000026587.15 Astn1 1 0 High P30115 Glutathione S-transferase A3 OS=Mus musculus OX=10090 GN=Gsta3 PE=1 SV=2 0 11.69 22 3 7 3 221 25.3 8.73 107859.3047 87709.92188 6268.381836 1 1 1 Met-loss+Acetyl [N-Term] metabolic process cytoplasm;cytosol catalytic activity;protein binding "Pf00043, Pf02798, Pf13417, Pf14497" 14859 ENSMUSG00000025934.15 Gsta3 1 Glutathione conjugation Glutathione metabolism; Platinum drug resistance; Drug metabolism - cytochrome P450; Chemical carcinogenesis; Metabolism of xenobiotics by cytochrome P450 0 High P97315 Cysteine and glycine-rich protein 1 OS=Mus musculus OX=10090 GN=Csrp1 PE=1 SV=3 0 17.773 29 3 7 3 193 20.6 8.57 211954.8201 75943.11816 3 2 cell organization and biogenesis cytoskeleton;nucleus metal ion binding;protein binding;RNA binding Pf00412 13007 ENSMUSG00000026421.14 Csrp1 1 0 High P49718 DNA replication licensing factor MCM5 OS=Mus musculus OX=10090 GN=Mcm5 PE=1 SV=2 0 9.147 6 4 7 4 734 82.4 8.29 13070.94824 1 0 High Q9EQH2 Endoplasmic reticulum aminopeptidase 1 OS=Mus musculus OX=10090 GN=Erap1 PE=1 SV=2 0 9.958 4 3 7 3 930 106.5 6.2 2328.194092 13898.23145 142505.5527 1 1 3 cell communication;metabolic process;regulation of biological process;response to stimulus cytoplasm;endoplasmic reticulum;extracellular;membrane;organelle lumen catalytic activity;metal ion binding;protein binding "Pf01433, Pf11838, Pf13485" 80898 ENSMUSG00000021583.6 Erap1 13 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC" 0 High E9PXX7 Thioredoxin domain-containing protein 5 OS=Mus musculus OX=10090 GN=Txndc5 PE=1 SV=1 0 15.692 18 4 7 4 344 38.5 5.39 64301.52344 59507.03125 1 1 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport endoplasmic reticulum;organelle lumen catalytic activity "Pf00085, Pf07449, Pf13098, Pf13905" 105245 ENSMUSG00000038991.16 Txndc5 13 0 High P47857 "ATP-dependent 6-phosphofructokinase, muscle type OS=Mus musculus OX=10090 GN=Pfkm PE=1 SV=3" 0 9.211 9 4 7 3 780 85.2 8 27211.44727 29211.91602 1 2 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process cytoplasm;cytosol;membrane;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding Pf00365 18642 ENSMUSG00000033065.13 Pfkm 15 Glycolysis RNA degradation; Metabolic pathways; Biosynthesis of amino acids; Glycolysis / Gluconeogenesis; Pentose phosphate pathway; AMPK signaling pathway; Carbon metabolism; Fructose and mannose metabolism; Galactose metabolism; Central carbon metabolism in cancer 0 High E9QNL5 Sulfotransferase OS=Mus musculus OX=10090 GN=Sult1a1 PE=1 SV=2 0 9.762 19 4 7 4 298 34.6 8.1 6776.453125 1 Met-loss+Acetyl [N-Term] 0 High Q64727 Vinculin OS=Mus musculus OX=10090 GN=Vcl PE=1 SV=4 0 13.43 8 5 7 5 1066 116.6 6 3716.787842 13120.80371 3382.871338 1 1 1 cell growth;cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton;membrane protein binding;structural molecule activity Pf01044 22330 ENSMUSG00000021823.9 Vcl 14 Platelet degranulation ; Neutrophil degranulation; Smooth Muscle Contraction Leukocyte transendothelial migration; Regulation of actin cytoskeleton; Focal adhesion; Adherens junction; Amoebiasis; Bacterial invasion of epithelial cells 0 High Q9D1M0 Protein SEC13 homolog OS=Mus musculus OX=10090 GN=Sec13 PE=1 SV=3 0 12.394 17 3 7 3 322 35.5 5.38 212825.9844 1 Met-loss+Acetyl [N-Term] cell organization and biogenesis;regulation of biological process;transport chromosome;cytosol;endoplasmic reticulum;membrane;nucleus;vacuole protein binding Pf00400 110379 ENSMUSG00000030298.10 Sec13 6 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal; Resolution of Sister Chromatid Cohesion; Separation of Sister Chromatids; RHO GTPases Activate Formins; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; MHC class II antigen presentation; COPII (Coat Protein 2) Mediated Vesicle Transport" mTOR signaling pathway; RNA transport; Protein processing in endoplasmic reticulum 0 High Q922Q1 Mitochondrial amidoxime reducing component 2 OS=Mus musculus OX=10090 GN=Mtarc2 PE=1 SV=1 0 14.209 17 5 7 4 338 38.2 8.68 229599.252 760683.7539 22288.84766 2 2 1 metabolic process membrane;mitochondrion catalytic activity;metal ion binding "Pf03473, Pf03476" 67247 ENSMUSG00000073481.9 Marc2; Mosc2 1 Phase I - Functionalization of compounds 0 Medium Q9ES03 T-box transcription factor TBX20 OS=Mus musculus OX=10090 GN=Tbx20 PE=2 SV=3 0.035 1.46 3 1 7 1 445 49.1 7.71 592641.3125 2563244 824613.3125 1340454.875 1 1 1 1 Acetyl [N-Term] cell differentiation;cell proliferation;cellular component movement;development;metabolic process;regulation of biological process cytoplasm;nucleus DNA binding;protein binding "Pf00907, Pf05872" 57246 ENSMUSG00000031965.15 Tbx20 9 0 High Q91WT7 3-alpha-hydroxysteroid dehydrogenase type 1 OS=Mus musculus OX=10090 GN=Akr1c14 PE=1 SV=1 0 7.901 14 4 7 3 323 37.2 7.2 metabolic process catalytic activity Pf00248 105387 ENSMUSG00000033715.14 Akr1c14 13 RA biosynthesis pathway; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; Signaling by GPCR; Retinoid metabolism and transport; Synthesis of bile acids and bile salts via 24-hydroxycholesterol; Synthesis of bile acids and bile salts via 27-hydroxycholesterol; Synthesis of Prostaglandins (PG) and Thromboxanes (TX) 0 High H3BL34 Carboxylic ester hydrolase OS=Mus musculus OX=10090 GN=Ces1e PE=1 SV=1 0 10.533 12 5 7 4 561 61.5 6.15 51700.09375 7239.823242 144125.3977 1 1 3 metabolic process endoplasmic reticulum catalytic activity "Pf00135, Pf00326, Pf00756, Pf07859" 13897 ENSMUSG00000061959.13 Ces1e 8 1 High Q62318 Transcription intermediary factor 1-beta OS=Mus musculus OX=10090 GN=Trim28 PE=1 SV=3 0 19.469 12 5 7 5 834 88.8 5.77 2129.867188 55337.58789 1 2 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus chromosome;nucleus catalytic activity;DNA binding;metal ion binding;protein binding;RNA binding "Pf00628, Pf00643" 21849 ENSMUSG00000005566.14 Trim28 7 Generic Transcription Pathway 0 High Q99M74 "Keratin, type II cuticular Hb2 OS=Mus musculus OX=10090 GN=Krt82 PE=1 SV=2" 0.003 3.659 3 2 7 2 516 57.1 6.25 1 1 355408.6724 1493671.5 365932.8125 520521.5227 2 1 1 2 structural molecule activity Pf00038 114566 ENSMUSG00000049548.8 Krt82 15 Formation of the cornified envelope 0 High Q61792 LIM and SH3 domain protein 1 OS=Mus musculus OX=10090 GN=Lasp1 PE=1 SV=1 0 12.759 21 5 7 5 263 30 7.05 39350.06055 40153.375 2 1 transport cytoplasm;cytoskeleton metal ion binding;protein binding;transporter activity "Pf00018, Pf00412, Pf00880, Pf07653, Pf14604" 16796 ENSMUSG00000038366.15 Lasp1 11 0 High Q5U465 Coiled-coil domain-containing protein 125 OS=Mus musculus OX=10090 GN=Ccdc125 PE=2 SV=2 0 10.489 10 4 6 4 500 56.6 6.84 6980.143066 156745.9648 43148.88281 1 4 3 cellular component movement;regulation of biological process cytoplasm Pf13851 76041 ENSMUSG00000048924.13 Ccdc125 13 0 High Q9JLV1 BAG family molecular chaperone regulator 3 OS=Mus musculus OX=10090 GN=Bag3 PE=1 SV=2 0 7.12 7 3 6 3 577 61.8 7.27 45174.60547 29142.89258 8909.458008 1 1 1 cell death;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;nucleus enzyme regulator activity;nucleotide binding;protein binding "Pf00397, Pf02179" 29810 ENSMUSG00000030847.8 Bag3 7 0 High Q8C7V3 U3 small nucleolar RNA-associated protein 15 homolog OS=Mus musculus OX=10090 GN=Utp15 PE=1 SV=1 0 8.058 8 3 6 3 528 59.3 8.79 metabolic process;regulation of biological process cytoplasm;endoplasmic reticulum;nucleus protein binding;RNA binding "Pf00400, Pf09384" 105372 ENSMUSG00000041747.2 Utp15 13 Major pathway of rRNA processing in the nucleolus and cytosol Ribosome biogenesis in eukaryotes 0 High Q9QXY6 EH domain-containing protein 3 OS=Mus musculus OX=10090 GN=Ehd3 PE=1 SV=2 0 8.677 9 3 6 3 535 60.8 6.46 11610.5498 1 cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;cytosol;endosome;membrane metal ion binding;nucleotide binding;protein binding "Pf00350, Pf01926, Pf12763" 57440 ENSMUSG00000024065.7 Ehd3 17 Factors involved in megakaryocyte development and platelet production Endocytosis 0 High A2ADH1 Magnesium transporter protein 1 OS=Mus musculus OX=10090 GN=Magt1 PE=1 SV=1 0 13.5 10 5 6 5 368 41.6 10.05 64512.33984 132891.9883 1 2 metabolic process;transport endoplasmic reticulum;membrane catalytic activity;transporter activity Pf04756 67075 ENSMUSG00000031232.16 Magt1 X Neutrophil degranulation; Miscellaneous transport and binding events 0 High O54749 Cytochrome P450 2J5 OS=Mus musculus OX=10090 GN=Cyp2j5 PE=1 SV=1 0 9.789 9 3 6 3 501 57.7 8.73 metabolic process;regulation of biological process;transport endoplasmic reticulum;membrane catalytic activity;metal ion binding Pf00067 13109 ENSMUSG00000052520.7 Cyp2j5 4 Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET); Fatty acids Ovarian steroidogenesis; Metabolic pathways; Linoleic acid metabolism; Arachidonic acid metabolism; Serotonergic synapse; Inflammatory mediator regulation of TRP channels 0 High Q60749 "KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Mus musculus OX=10090 GN=Khdrbs1 PE=1 SV=2" 0 6.368 5 2 6 2 443 48.3 8.72 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus protein binding;RNA binding "Pf00013, Pf13014" 20218 ENSMUSG00000028790.13 Khdrbs1 4 PTK6 Regulates Proteins Involved in RNA Processing 0 High J3QMG3 Voltage-dependent anion-selective channel protein 3 OS=Mus musculus OX=10090 GN=Vdac3 PE=1 SV=1 0 10.597 11 2 6 2 284 30.8 8.79 40410.39063 118584.3918 20171.08105 1 2 2 Met-loss+Acetyl [N-Term] regulation of biological process;transport membrane;mitochondrion transporter activity Pf01459 ENSMUSG00000008892.12 8 0 High Q9Z2N8 Actin-like protein 6A OS=Mus musculus OX=10090 GN=Actl6a PE=1 SV=2 0 6.401 9 3 6 3 429 47.4 5.6 448933.085 257823.4883 235203.6836 253212.6831 3 2 2 2 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus membrane;nucleus DNA binding;protein binding Pf00022 56456 ENSMUSG00000027671.14 Actl6a 3 DNA Damage Recognition in GG-NER; RMTs methylate histone arginines; UCH proteinases; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 0 High A0A075B5P8 Immunoglobulin heavy variable 2-2 (Fragment) OS=Mus musculus OX=10090 GN=Ighv2-2 PE=4 SV=1 0 8.483 14 1 6 1 116 12.6 8.48 1 1 3 1 958137.125 242260.7188 62032.28516 2 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000096464.2 LOC674126 12 0 High A0A075B5V5 Immunoglobulin heavy variable 1-39 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-39 PE=4 SV=1 0.002 5.277 13 1 6 1 117 12.9 8.41 1 2 1466913.75 326616.7188 112507.8516 1 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding "Pf00047, Pf07686" ENSMUSG00000095130.1 12 0 High A0A0N4SW28 Guanine nucleotide-binding protein subunit gamma OS=Mus musculus OX=10090 GN=Gng12 PE=1 SV=1 0 14.822 39 3 6 3 83 9.2 9.25 regulation of biological process;response to stimulus membrane signal transducer activity Pf00631 ENSMUSG00000036402.13 6 0 High D3Z4J5 Golgi to ER traffic protein 4 homolog (Fragment) OS=Mus musculus OX=10090 GN=Get4 PE=1 SV=1 0 9.761 17 3 6 3 246 27.6 6.95 85128.49707 122460.584 48925.01563 12760.78711 2 4 1 1 Met-loss+Acetyl [N-Term] Pf04190 ENSMUSG00000025858.12 5 0 High E0CZD7 Traf2 and NCK-interacting protein kinase OS=Mus musculus OX=10090 GN=Tnik PE=1 SV=1 0.002 5.192 3 2 6 1 1276 145.1 7.06 1379344.75 513212.875 287838.4063 1 1 1 metabolic process catalytic activity;nucleotide binding "Pf00069, Pf00780, Pf07714, Pf14531" ENSMUSG00000027692.16 3 0 High E0CX53 TBC1 domain family member 4 OS=Mus musculus OX=10090 GN=Tbc1d4 PE=1 SV=1 0 6.046 4 3 6 3 1306 147.2 7.39 1 1 132680.2852 106779.7441 105355.4434 2 2 2 regulation of biological process;response to stimulus;transport cytoplasm;cytosol enzyme regulator activity;protein binding "Pf00566, Pf00640, Pf11830" 210789 ENSMUSG00000033083.16 Tbc1d4 14 Translocation of GLUT4 to the plasma membrane 0 High E9PVB5 Tetratricopeptide repeat protein 17 OS=Mus musculus OX=10090 GN=Ttc17 PE=1 SV=1 0 11.362 8 6 6 6 1198 135.4 6.47 5579.25 16356.88867 1 1 cell organization and biogenesis cytoplasm;cytoskeleton;cytosol;membrane catalytic activity;nucleotide binding;protein binding "Pf00515, Pf02841, Pf13414, Pf13424, Pf13432" 74569 ENSMUSG00000027194.16 Ttc17 2 0 High A0A0R4J0B4 N-acylneuraminate cytidylyltransferase OS=Mus musculus OX=10090 GN=Cmas PE=1 SV=1 0.003 3.562 6 2 6 2 432 48 8.1 26643.625 1 metabolic process membrane;nucleus catalytic activity "Pf02348, Pf12804" 12764 ENSMUSG00000030282.14 Cmas 6 Sialic acid metabolism Metabolic pathways; Amino sugar and nucleotide sugar metabolism 0 High D3Z7C6 Prostaglandin E synthase 3 OS=Mus musculus OX=10090 GN=Ptges3 PE=1 SV=1 0 5.8 15 2 6 2 130 15 4.79 66857.15039 31646.15625 2 1 cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process;response to stimulus protein binding Pf04969 ENSMUSG00000071072.12 10 0 High O54950 5'-AMP-activated protein kinase subunit gamma-1 OS=Mus musculus OX=10090 GN=Prkag1 PE=1 SV=2 0 9.011 9 2 6 2 330 37.5 7.14 9931.821289 17087.1731 1 2 cell organization and biogenesis;metabolic process;regulation of biological process;transport cytosol;membrane;nucleus catalytic activity;nucleotide binding;protein binding Pf00571 19082 ENSMUSG00000067713.6 Prkag1 15 Macroautophagy; Regulation of TP53 Activity through Phosphorylation; Energy dependent regulation of mTOR by LKB1-AMPK; TP53 Regulates Metabolic Genes Oxytocin signaling pathway; FoxO signaling pathway; Hypertrophic cardiomyopathy (HCM); Insulin signaling pathway; Insulin resistance; Circadian rhythm; Longevity regulating pathway; Non-alcoholic fatty liver disease (NAFLD); Adipocytokine signaling pathway; AMPK signaling pathway; Glucagon signaling pathway; Longevity regulating pathway - multiple species 0 High Q6DYE8 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 OS=Mus musculus OX=10090 GN=Enpp3 PE=1 SV=2 0 14.942 9 6 6 6 874 98.6 6.52 metabolic process;response to stimulus;transport extracellular;membrane catalytic activity;metal ion binding;receptor activity "Pf01033, Pf01223, Pf01663, Pf01676" 209558 ENSMUSG00000019989.8 Enpp3 10 Metabolic pathways; Nicotinate and nicotinamide metabolism; Purine metabolism; Starch and sucrose metabolism; Pyrimidine metabolism; Pantothenate and CoA biosynthesis 0 High Z4YKH8 "Troponin T, fast skeletal muscle OS=Mus musculus OX=10090 GN=Tnnt3 PE=1 SV=1" 0 12.747 19 4 6 3 259 30.6 6.2 123103.7446 216100.0957 60400.57617 68101.90234 4 3 2 3 regulation of biological process ENSMUSG00000061723.18 7 Striated Muscle Contraction 1 High G5E850 Cytochrome b5 OS=Mus musculus OX=10090 GN=Cyb5a PE=1 SV=1 0 13.774 43 3 6 3 98 11.1 5.3 5660.140137 100720.6084 2 1 metabolic process;transport cytosol;endoplasmic reticulum;membrane;mitochondrion catalytic activity;metal ion binding;protein binding Pf00173 109672 ENSMUSG00000024646.13 Cyb5; Cyb5a 18 0 High Q5SSI6 U3 small nucleolar RNA-associated protein 18 homolog OS=Mus musculus OX=10090 GN=Utp18 PE=1 SV=1 0 12.911 8 3 6 3 552 61.2 8.78 2171.789307 40155.10156 3027.299561 1 1 1 metabolic process membrane;nucleus protein binding;RNA binding 217109 ENSMUSG00000054079.12 Utp18 11 Major pathway of rRNA processing in the nucleolus and cytosol Ribosome biogenesis in eukaryotes 0 High O70318 Band 4.1-like protein 2 OS=Mus musculus OX=10090 GN=Epb41l2 PE=1 SV=2 0 9.869 4 2 6 1 988 109.9 5.43 cell division;cell organization and biogenesis;regulation of biological process;transport cytoplasm;cytoskeleton;membrane;nucleus protein binding;structural molecule activity "Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380" 13822 ENSMUSG00000019978.16 Epb4.1l2; Epb41l2 10 Neurexins and neuroligins Tight junction 0 High Q99LB7 "Sarcosine dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Sardh PE=1 SV=1" 0 11.41 4 3 6 3 919 101.6 6.74 25569.4939 10039.34863 10419.14063 3145.802734 2 1 1 1 metabolic process mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf01266, Pf01571, Pf08669" 192166 ENSMUSG00000009614.16 Sardh 2 Choline catabolism "Metabolic pathways; Glycine, serine and threonine metabolism" 0 High Q8C4J7 Transducin beta-like protein 3 OS=Mus musculus OX=10090 GN=Tbl3 PE=2 SV=1 0 8.785 8 4 6 4 801 88.2 6.81 9547.023438 7778.494629 1 1 metabolic process nucleus protein binding;RNA binding "Pf00400, Pf08625" 213773 ENSMUSG00000040688.16 Tbl3 17 Major pathway of rRNA processing in the nucleolus and cytosol Ribosome biogenesis in eukaryotes 0 High Q9QXD1 Peroxisomal acyl-coenzyme A oxidase 2 OS=Mus musculus OX=10090 GN=Acox2 PE=1 SV=2 0 8.997 7 4 6 4 681 76.8 7.46 34219.91846 17762.82617 2 1 metabolic process;regulation of biological process mitochondrion catalytic activity;nucleotide binding;protein binding "Pf01756, Pf14749" 93732 ENSMUSG00000021751.13 Acox2 14 Beta-oxidation of pristanoyl-CoA; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol PPAR signaling pathway; Metabolic pathways; Primary bile acid biosynthesis; Peroxisome 0 High Q9Z329 "Inositol 1,4,5-trisphosphate receptor type 2 OS=Mus musculus OX=10090 GN=Itpr2 PE=1 SV=4" 0 11.813 2 4 6 4 2701 307.3 6.44 1 1 43394.62354 105221 9990.546875 3 2 1 cellular homeostasis;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;membrane;nucleus metal ion binding;protein binding;receptor activity;signal transducer activity;transporter activity "Pf01365, Pf02815, Pf08454, Pf08709, Pf12670" 16439 ENSMUSG00000030287.15 Itpr2 6 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Ion homeostasis; Effects of PIP2 hydrolysis; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Gastrin-CREB signalling pathway via PKC and MAPK; Elevation of cytosolic Ca2+ levels Oxytocin signaling pathway; Cholinergic synapse; Retrograde endocannabinoid signaling; Pancreatic secretion; Dopaminergic synapse; NOD-like receptor signaling pathway; Long-term potentiation; Platelet activation; Thyroid hormone synthesis; Oocyte meiosis; Glutamatergic synapse; Proteoglycans in cancer; Long-term depression; cGMP-PKG signaling pathway; Calcium signaling pathway; Salivary secretion; Alzheimer's disease; Vascular smooth muscle contraction; Aldosterone synthesis and secretion; GnRH signaling pathway; Gastric acid secretion; Renin secretion; Gap junction; Estrogen signaling pathway; Glucagon signaling pathway; Phosphatidylinositol signaling system; Serotonergic synapse; Inflammatory mediator regulation of TRP channels; Apoptosis 0 High Q9JI95 CPN10-like protein OS=Mus musculus OX=10090 GN=Hspe1-rs1 PE=3 SV=1 0 9.475 33 3 6 3 102 11 8.92 72981.73828 149001.5469 48590.19531 17596.89063 3 2 2 1 metabolic process cytoplasm Pf00166 628438 Hspe1-rs1 18 0 High Q9DBG7 Signal recognition particle receptor subunit alpha OS=Mus musculus OX=10090 GN=Srpra PE=1 SV=1 0 8.755 6 3 6 3 636 69.6 8.95 3534.640137 35687.52344 1 1 cell organization and biogenesis;transport endoplasmic reticulum;membrane catalytic activity;nucleotide binding;RNA binding "Pf00448, Pf02881, Pf04086" 67398 ENSMUSG00000032042.11 Srpr 9 Protein export 0 High Q6PDJ6 F-box only protein 42 OS=Mus musculus OX=10090 GN=Fbxo42 PE=1 SV=1 0 9.393 6 3 6 3 717 77.7 7.58 4948.928711 56962.14453 1 1 protein binding "Pf00646, Pf01344, Pf07646, Pf12937, Pf13415, Pf13418, Pf13854, Pf13964" 213499 ENSMUSG00000028920.9 Fbxo42 4 0 High Q9EQ32 Phosphoinositide 3-kinase adapter protein 1 OS=Mus musculus OX=10090 GN=Pik3ap1 PE=1 SV=1 0 8.26 6 4 6 4 811 90.9 5.17 26144.78125 803298.8262 14032.00586 1 2 1 regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;nucleus protein binding Pf14545 83490 ENSMUSG00000025017.9 Pik3ap1 19 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers" B cell receptor signaling pathway; PI3K-Akt signaling pathway 0 High Q8CHR6 Dihydropyrimidine dehydrogenase [NADP(+)] OS=Mus musculus OX=10090 GN=Dpyd PE=1 SV=1 0 6.079 4 3 6 3 1025 111.2 7.27 11033.26172 14539.86621 12917.8999 2 1 2 metabolic process;response to stimulus cytoplasm;cytosol catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf01180, Pf01207, Pf07992, Pf12838, Pf13183, Pf13187, Pf13237, Pf13450, Pf14691, Pf14697" 99586 ENSMUSG00000033308.16 Dpyd 3 Pyrimidine catabolism Metabolic pathways; beta-Alanine metabolism; Pyrimidine metabolism; Drug metabolism - other enzymes; Pantothenate and CoA biosynthesis 0 High A0A0A0MQM2 Phosphoinositide phospholipase C OS=Mus musculus OX=10090 GN=Plch1 PE=1 SV=1 0.007 2.301 1 1 6 1 1073 122.5 7.72 644864.8789 1 metabolic process;regulation of biological process;response to stimulus catalytic activity;metal ion binding;protein binding;signal transducer activity "Pf00036, Pf00168, Pf00387, Pf00388, Pf09279, Pf13499, Pf14788" ENSMUSG00000036834.16 3 0 High A0A1B0GRR8 U1 small nuclear ribonucleoprotein 70 kDa (Fragment) OS=Mus musculus OX=10090 GN=Snrnp70 PE=1 SV=1 0 14.162 36 5 6 5 168 20 7.53 20883.0835 51968.13281 3 1 RNA binding "Pf00076, Pf12220, Pf13893, Pf14259" ENSMUSG00000063511.11 7 0 High Q6XVG2 Cytochrome P450 2C54 OS=Mus musculus OX=10090 GN=Cyp2c54 PE=1 SV=1 0 18.659 8 3 6 2 490 55.8 7.47 metabolic process endoplasmic reticulum;membrane catalytic activity;metal ion binding Pf00067 404195 ENSMUSG00000067225.1 Cyp2c54 19 Steroid hormone biosynthesis; Retinol metabolism; Metabolic pathways; Linoleic acid metabolism; Arachidonic acid metabolism; Chemical carcinogenesis; Serotonergic synapse; Inflammatory mediator regulation of TRP channels 0 High Q9CYD3 Cartilage-associated protein OS=Mus musculus OX=10090 GN=Crtap PE=1 SV=3 0 12.965 18 6 6 6 400 46.1 5.71 28554.82813 280565.293 1 5 metabolic process;regulation of biological process endoplasmic reticulum;extracellular protein binding 56693 ENSMUSG00000032431.6 Crtap 9 Collagen biosynthesis and modifying enzymes 0 High Q07417 "Short-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Acads PE=1 SV=2" 0 8.024 13 4 6 4 412 44.9 8.47 1 1 203939.2285 101552.2148 91701.17969 62567.80469 3 2 1 2 cell organization and biogenesis;metabolic process membrane;mitochondrion;nucleus;organelle lumen catalytic activity;nucleotide binding "Pf00441, Pf02770, Pf02771, Pf08028" 11409 ENSMUSG00000029545.13 Acads 5 Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA "Fatty acid metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Fatty acid degradation; Butanoate metabolism; Carbon metabolism" 0 High P10852 4F2 cell-surface antigen heavy chain OS=Mus musculus OX=10090 GN=Slc3a2 PE=1 SV=1 0 9.66 9 3 6 3 526 58.3 5.91 20530.50195 39749.87109 1 1 metabolic process;response to stimulus;transport cell surface;cytosol;membrane;nucleus catalytic activity;protein binding;RNA binding;transporter activity Pf00128 17254 ENSMUSG00000010095.13 Slc3a2 19 Amino acid transport across the plasma membrane; Tryptophan catabolism; Basigin interactions mTOR signaling pathway; Protein digestion and absorption 0 High E9Q8B6 Predicted gene 4788 OS=Mus musculus OX=10090 GN=Gm4788 PE=1 SV=1 0 10.699 6 5 6 5 820 92.8 7.17 34158.05566 4352.704102 2 1 Pf00084 214403 ENSMUSG00000070594.10 Gm4788 1 Regulation of Complement cascade 0 High A0A0N4SV00 T-complex protein 1 subunit eta OS=Mus musculus OX=10090 GN=Cct7 PE=1 SV=1 0 6.875 7 4 6 4 502 55 7.83 276890.5889 38658.72363 55805.80859 39696.03516 3 2 1 1 metabolic process;transport cytoplasm;mitochondrion nucleotide binding;protein binding Pf00118 ENSMUSG00000030007.8 6 0 High Q8BK64 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Mus musculus OX=10090 GN=Ahsa1 PE=1 SV=2 0 8.118 18 4 6 4 338 38.1 5.53 33512.83203 3576.907227 1 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;endoplasmic reticulum enzyme regulator activity;protein binding "Pf08327, Pf09229" 217737 ENSMUSG00000021037.6 Ahsa1 12 0 High Q8K1N2 Pleckstrin homology-like domain family B member 2 OS=Mus musculus OX=10090 GN=Phldb2 PE=1 SV=2 0 14.729 7 6 6 6 1249 141.4 7.68 cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;cytosol;Golgi;membrane catalytic activity;motor activity;protein binding "Pf00169, Pf01576, Pf02463, Pf03234, Pf03938, Pf04111, Pf04156, Pf05483, Pf05667, Pf07701, Pf09730, Pf09731, Pf10174, Pf10473, Pf12128, Pf13166, Pf13851, Pf13868, Pf14943, Pf14992, Pf15413" 208177 ENSMUSG00000033149.16 Phldb2 16 0 High Q8CH72 E3 ubiquitin-protein ligase TRIM32 OS=Mus musculus OX=10090 GN=Trim32 PE=1 SV=2 0 6.777 4 2 6 2 655 72 6.9 32267.57227 29476.42578 17898.44922 1 1 1 Met-loss+Acetyl [N-Term] cell differentiation;cell organization and biogenesis;cellular homeostasis;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus catalytic activity;metal ion binding;protein binding;RNA binding "Pf00097, Pf00643, Pf01436, Pf10186, Pf13445, Pf13639, Pf13920, Pf13923, Pf14570, Pf14634, Pf15227" 69807 ENSMUSG00000051675.13 Trim32 4 Regulation of innate immune responses to cytosolic DNA Ubiquitin mediated proteolysis 0 High O35326 Serine/arginine-rich splicing factor 5 OS=Mus musculus OX=10090 GN=Srsf5 PE=1 SV=2 0.002 4.337 6 2 6 1 269 30.9 11.56 7664.790039 13846.73438 7070.192871 7983.831055 1 1 1 1 metabolic process;regulation of biological process;response to stimulus nucleus protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 20384 ENSMUSG00000021134.17 Srsf5 12 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript Herpes simplex infection; Spliceosome 0 High Q60584 F-box/WD repeat-containing protein 2 OS=Mus musculus OX=10090 GN=Fbxw2 PE=2 SV=2 0 7.136 11 3 6 3 422 47.9 6.79 1 1 126601.9609 11871.30273 44386.53711 2 1 2 metabolic process cytoplasm;nucleus catalytic activity;protein binding "Pf00400, Pf12937" 30050 Fbxw2 2 0 High G3UY93 Valyl-tRNA synthetase (Fragment) OS=Mus musculus OX=10090 GN=Vars PE=1 SV=1 0 8.573 3 3 6 3 1278 141.3 7.75 28980.87573 33264.28125 7854.755371 2 2 1 metabolic process;regulation of biological process cytoplasm catalytic activity;nucleotide binding "Pf00043, Pf00133, Pf08264, Pf09334, Pf13603" ENSMUSG00000007029.16 17 0 High Q9QXD6 "Fructose-1,6-bisphosphatase 1 OS=Mus musculus OX=10090 GN=Fbp1 PE=1 SV=3" 0.002 4.588 8 2 6 2 338 36.9 6.57 42375.52344 37411.96484 98830.27344 13528.15918 1 1 1 1 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00316, Pf00459" 14121 ENSMUSG00000069805.10 Fbp1 13 Gluconeogenesis Insulin signaling pathway; Metabolic pathways; Glycolysis / Gluconeogenesis; Pentose phosphate pathway; AMPK signaling pathway; Carbon metabolism; Fructose and mannose metabolism; Glucagon signaling pathway 0 High Q8VCU2 Glycosylphosphatidylinositol specific phospholipase D1 OS=Mus musculus OX=10090 GN=Gpld1 PE=1 SV=1 0 18.536 8 5 6 5 842 93.6 6.8 130961.2456 2 cell differentiation;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;extracellular;membrane catalytic activity;protein binding "Pf00882, Pf01839, Pf13517" 14756 ENSMUSG00000021340.12 Gpld1 13 Post-translational modification: synthesis of GPI-anchored proteins Glycosylphosphatidylinositol (GPI)-anchor biosynthesis 0 High Q542V3 Serine/arginine-rich-splicing factor 4 OS=Mus musculus OX=10090 GN=Srsf4 PE=1 SV=1 0.002 4.753 3 2 6 1 491 56.2 11.37 5344.956543 12849.26172 1 1 cell differentiation;metabolic process;regulation of biological process;response to stimulus nucleus RNA binding "Pf00076, Pf13893, Pf14259" 57317 ENSMUSG00000028911.16 Srsf4 4 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript Herpes simplex infection; Spliceosome 0 High F6YX19 Phosphatidylinositol-glycan biosynthesis class X protein OS=Mus musculus OX=10090 GN=Pigx PE=1 SV=1 0 10.994 25 4 6 4 252 28.4 6.4 10597.74902 5130.737305 79050.14771 1 1 3 metabolic process membrane Pf08320 ENSMUSG00000023791.15 16 0 High P62855 40S ribosomal protein S26 OS=Mus musculus OX=10090 GN=Rps26 PE=1 SV=3 0 5.545 18 2 6 2 115 13 11 41488.65625 56908.625 1 1 metabolic process;regulation of biological process membrane;ribosome protein binding;RNA binding;structural molecule activity Pf01283 27370; 100042812 ENSMUSG00000025362.6 Rps26; Rps26-ps1 10; 8 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High Q922J9 Fatty acyl-CoA reductase 1 OS=Mus musculus OX=10090 GN=Far1 PE=1 SV=1 0 8.979 7 3 6 3 515 59.4 9.19 70731.82031 185226.2031 34985.36328 1 1 1 metabolic process membrane catalytic activity "Pf01370, Pf03015, Pf07993" 67420 ENSMUSG00000030759.16 Far1 7 Wax biosynthesis Peroxisome 0 High Q3UVK0 Endoplasmic reticulum metallopeptidase 1 OS=Mus musculus OX=10090 GN=Ermp1 PE=1 SV=2 0 12.203 10 6 6 6 898 100.1 7.49 223889.0918 5 metabolic process endoplasmic reticulum;membrane catalytic activity;metal ion binding "Pf04389, Pf14264" 226090 ENSMUSG00000046324.12 Ermp1 19 0 High P51658 Estradiol 17-beta-dehydrogenase 2 OS=Mus musculus OX=10090 GN=Hsd17b2 PE=1 SV=2 0 14.819 19 6 6 6 381 41.8 8.57 43585.95996 25933.25 2 1 metabolic process;response to stimulus membrane catalytic activity "Pf00106, Pf08643, Pf13561" 15486 ENSMUSG00000031844.8 Hsd17b2 8 Estrogen biosynthesis Steroid hormone biosynthesis; Ovarian steroidogenesis; Metabolic pathways 0 High E9PYI7 LIM domain only 7 OS=Mus musculus OX=10090 GN=Lmo7 PE=1 SV=1 0 10.775 2 3 6 3 1453 164.6 5.73 Acetyl [N-Term] metabolic process;regulation of biological process membrane catalytic activity;protein binding "Pf00595, Pf13180" 380928 ENSMUSG00000033060.15 Lmo7 14 Neddylation; Antigen processing: Ubiquitination & Proteasome degradation 0 High P25206 DNA replication licensing factor MCM3 OS=Mus musculus OX=10090 GN=Mcm3 PE=1 SV=2 0 9.821 6 4 5 4 812 91.5 5.55 2985.047363 215302.0313 99029.72656 1 1 1 metabolic process cytoplasm;membrane;nucleus catalytic activity;DNA binding;nucleotide binding "Pf00493, Pf01078, Pf07728, Pf14551" 17215 ENSMUSG00000041859.10 Mcm3 1 Removal of licensing factors from origins; Activation of the pre-replicative complex; Assembly of the pre-replicative complex; Orc1 removal from chromatin; M/G1 Transition; Activation of ATR in response to replication stress; Regulation of DNA replication DNA replication; Cell cycle 0 High A0A0R4J1H2 Glycerate kinase OS=Mus musculus OX=10090 GN=Glyctk PE=1 SV=1 0 5.994 13 3 5 3 523 55.3 6.67 metabolic process cytoplasm;cytosol;Golgi;mitochondrion catalytic activity;nucleotide binding "Pf05161, Pf13660" 235582 ENSMUSG00000020258.16 Glyctk 9 Fructose catabolism "Metabolic pathways; Glycine, serine and threonine metabolism; Pentose phosphate pathway; Carbon metabolism; Glycerolipid metabolism; Glyoxylate and dicarboxylate metabolism" 0 High P32261 Antithrombin-III OS=Mus musculus OX=10090 GN=Serpinc1 PE=1 SV=1 0 12.583 14 4 5 4 465 52 6.46 65686.83008 10887.64648 10199.40381 2 1 2 coagulation;defense response;regulation of biological process;response to stimulus;transport extracellular enzyme regulator activity;protein binding Pf00079 11905 ENSMUSG00000026715.12 Serpinc1 1 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Common Pathway of Fibrin Clot Formation; Intrinsic Pathway of Fibrin Clot Formation; Post-translational protein phosphorylation Complement and coagulation cascades 0 High A0A140LIZ5 26S proteasome regulatory subunit 6B OS=Mus musculus OX=10090 GN=Psmc4 PE=1 SV=1 0 6.745 11 3 5 3 387 43.5 5.26 metabolic process;regulation of biological process;response to stimulus cytoplasm catalytic activity;nucleotide binding;RNA binding "Pf00004, Pf00006, Pf00910, Pf01057, Pf01078, Pf05496, Pf07724, Pf07726, Pf07728, Pf13191" ENSMUSG00000030603.16 7 0 High Q99LE6 ATP-binding cassette sub-family F member 2 OS=Mus musculus OX=10090 GN=Abcf2 PE=1 SV=1 0 10.212 7 4 5 4 628 71.7 7.05 9411.771484 16532.11328 1 1 membrane;mitochondrion catalytic activity;nucleotide binding "Pf00005, Pf12848" 27407 ENSMUSG00000028953.10 Abcf2 5 0 High E9QNY3 Myosin regulatory light chain 10 OS=Mus musculus OX=10090 GN=Myl10 PE=1 SV=1 0 6.228 7 1 5 1 147 16.9 4.7 2861.030273 28830.87305 7019.818848 1 2 1 Met-loss [N-Term] mitochondrion metal ion binding;protein binding "Pf00036, Pf13405" 59310 ENSMUSG00000005474.9 Myl10 5 0 High A0A075B5L3 Immunoglobulin kappa chain variable 4-90 (Fragment) OS=Mus musculus OX=10090 GN=Igkv4-90 PE=4 SV=5 0 6.207 14 1 5 1 117 12.6 5.11 1 1 203938.7344 1 response to stimulus "Pf00047, Pf07686" 434034 ENSMUSG00000076533.3 Igkv4-90 6 0 High Q9R0E2 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 OS=Mus musculus OX=10090 GN=Plod1 PE=1 SV=1" 0 7.102 9 4 5 4 728 83.5 6.54 38599.77734 34043.60156 22523.67383 113417.4873 1 2 1 4 metabolic process;response to stimulus endoplasmic reticulum;membrane catalytic activity;metal ion binding;protein binding Pf03171 18822 ENSMUSG00000019055.15 Plod1 4 Collagen biosynthesis and modifying enzymes Lysine degradation 0 High Q61881 DNA replication licensing factor MCM7 OS=Mus musculus OX=10090 GN=Mcm7 PE=1 SV=1 0 7.089 7 4 5 4 719 81.2 6.37 3294.779053 1 cell proliferation;metabolic process;regulation of biological process;response to stimulus cytosol;membrane;nucleus catalytic activity;DNA binding;nucleotide binding;protein binding "Pf00493, Pf07728, Pf14551" 17220 ENSMUSG00000029730.16 Mcm7 5 Removal of licensing factors from origins; Activation of the pre-replicative complex; Assembly of the pre-replicative complex; Orc1 removal from chromatin; M/G1 Transition; Activation of ATR in response to replication stress; Regulation of DNA replication DNA replication; Cell cycle 0 High O89023 Tripeptidyl-peptidase 1 OS=Mus musculus OX=10090 GN=Tpp1 PE=1 SV=2 0 13.526 9 3 5 3 562 61.3 6.57 141703.4727 104805.6914 25151.70313 124564.5781 1 2 1 3 cell differentiation;cell organization and biogenesis;metabolic process mitochondrion;vacuole catalytic activity;metal ion binding;protein binding "Pf00082, Pf09286" 12751 ENSMUSG00000030894.5 Tpp1 7 Lysosome 0 High Q8BH59 Calcium-binding mitochondrial carrier protein Aralar1 OS=Mus musculus OX=10090 GN=Slc25a12 PE=1 SV=1 0 7.732 6 4 5 2 677 74.5 8.25 40450.37109 13531.62793 8543.086914 1 1 1 response to stimulus;transport membrane;mitochondrion metal ion binding;transporter activity "Pf00153, Pf13499" 78830 ENSMUSG00000027010.16 Slc25a12 2 Gluconeogenesis 0 High P59325 Eukaryotic translation initiation factor 5 OS=Mus musculus OX=10090 GN=Eif5 PE=1 SV=1 0 7.653 10 4 5 4 429 48.9 5.52 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;cytosol;membrane nucleotide binding;protein binding;RNA binding "Pf01873, Pf02020" 217869; 102641436 ENSMUSG00000021282.16 Eif5; LOC100047658; LOC102641436 12; 10 Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit RNA transport 0 High Q80ZW2 Protein THEM6 OS=Mus musculus OX=10090 GN=Them6 PE=1 SV=1 0 6.785 9 2 5 2 207 23.8 9.11 7740.892334 6167.646729 44830.56641 36300.74561 2 1 1 1 extracellular "Pf03061, Pf13279" 223626 ENSMUSG00000056665.2 4930572J05Rik; Them6 15 0 High Q91WM3 U3 small nucleolar RNA-interacting protein 2 OS=Mus musculus OX=10090 GN=Rrp9 PE=1 SV=1 0.002 4.756 7 3 5 3 475 52.1 7.88 4132.146973 13176.22656 1 1 metabolic process nucleus protein binding;RNA binding Pf00400 27966 ENSMUSG00000041506.15 Rrp9 9 Major pathway of rRNA processing in the nucleolus and cytosol 0 High P08121 Collagen alpha-1(III) chain OS=Mus musculus OX=10090 GN=Col3a1 PE=1 SV=4 0 7.085 5 4 5 4 1464 138.9 6.52 2 1 3 1 473897.582 512493.0391 118905.2344 17860.73242 3 3 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus extracellular metal ion binding;protein binding;structural molecule activity "Pf00093, Pf01391, Pf01410, Pf14828" 12825 ENSMUSG00000026043.18 Col3a1 1 ECM proteoglycans; Collagen chain trimerization; Integrin cell surface interactions; MET activates PTK2 signaling; NCAM1 interactions; Collagen degradation; Non-integrin membrane-ECM interactions; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; Signaling by PDGF; Assembly of collagen fibrils and other multimeric structures AGE-RAGE signaling pathway in diabetic complications; Protein digestion and absorption; Platelet activation; Amoebiasis 0 Low Q8BH82 N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D OS=Mus musculus OX=10090 GN=Napepld PE=1 SV=1 0.073 1.195 2 1 5 1 396 45.8 5.94 37627.125 62416.01953 106633.9688 1 1 1 metabolic process;response to stimulus cytosol;membrane catalytic activity;metal ion binding;protein binding "Pf00753, Pf12706, Pf13483" 242864 ENSMUSG00000044968.16 Napepld 5 Retrograde endocannabinoid signaling 0 High A0A0A6YY60 Immunoglobulin heavy variable V8-5 (Fragment) OS=Mus musculus OX=10090 GN=Ighv8-5 PE=4 SV=1 0 7.124 26 2 5 2 119 13.2 8.46 173879.2969 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000102364.1 12 Regulation of Complement cascade; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Cell surface interactions at the vascular wall; FCERI mediated NF-kB activation; Role of LAT2/NTAL/LAB on calcium mobilization; Role of phospholipids in phagocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR activation; Classical antibody-mediated complement activation; FCERI mediated Ca+2 mobilization; FCERI mediated MAPK activation; CD22 mediated BCR regulation; Scavenging of heme from plasma 0 High G5E881 "Phosphatidate cytidylyltransferase, mitochondrial OS=Mus musculus OX=10090 GN=Tamm41 PE=1 SV=1" 0 7.869 7 2 5 2 337 37.9 9.11 2359.443115 18433.05273 73751.07617 1 1 2 Met-loss+Acetyl [N-Term] metabolic process membrane;mitochondrion catalytic activity Pf09139 68971 ENSMUSG00000030316.13 Tamm41 6 0 High Q9QWR8 Alpha-N-acetylgalactosaminidase OS=Mus musculus OX=10090 GN=Naga PE=1 SV=2 0 9.379 9 3 5 3 415 47.2 6.44 3196.292236 45755.23828 86230.07422 1 1 2 metabolic process cytoplasm;vacuole catalytic activity;protein binding Pf02065 17939 ENSMUSG00000022453.7 Naga 15 Glycosphingolipid biosynthesis - globo and isoglobo series; Lysosome 0 High Q922Q8 Leucine-rich repeat-containing protein 59 OS=Mus musculus OX=10090 GN=Lrrc59 PE=1 SV=1 0 7.758 11 3 5 3 307 34.9 9.52 46882.53223 128933.1602 6912.999023 47998.15088 2 2 1 2 endoplasmic reticulum;membrane;nucleus protein binding;RNA binding "Pf12799, Pf13855" 98238 ENSMUSG00000020869.8 Lrrc59 11 0 High E9Q7C8 Cytochrome P450 2C40 OS=Mus musculus OX=10090 GN=Cyp2c40 PE=3 SV=1 0 8.141 7 3 5 1 520 59.1 7.93 2530.148438 8641.301758 12162.1582 1 1 1 metabolic process endoplasmic reticulum;membrane catalytic activity;metal ion binding Pf00067 13099 ENSMUSG00000025004.15 Cyp2c40 19 Steroid hormone biosynthesis; Retinol metabolism; Metabolic pathways; Linoleic acid metabolism; Arachidonic acid metabolism; Chemical carcinogenesis; Serotonergic synapse; Inflammatory mediator regulation of TRP channels 2 High P50172 Corticosteroid 11-beta-dehydrogenase isozyme 1 OS=Mus musculus OX=10090 GN=Hsd11b1 PE=1 SV=3 0 6.293 12 3 5 3 292 32.3 8.46 56412.01611 150414.875 3 3 metabolic process;regulation of biological process cytoplasm;endoplasmic reticulum;membrane catalytic activity;nucleotide binding "Pf00106, Pf08643, Pf08659, Pf13460, Pf13561" 15483 ENSMUSG00000016194.14 Hsd11b1 1 Glucocorticoid biosynthesis Steroid hormone biosynthesis; Metabolic pathways; Chemical carcinogenesis; Metabolism of xenobiotics by cytochrome P450 0 High P47758 Signal recognition particle receptor subunit beta OS=Mus musculus OX=10090 GN=Srprb PE=1 SV=1 0 9.867 20 4 5 4 269 29.6 9.28 regulation of biological process;response to stimulus cytoplasm;endoplasmic reticulum;membrane nucleotide binding;protein binding "Pf00009, Pf00025, Pf01926, Pf09439" 20818 ENSMUSG00000032553.14 Srprb 9 Protein export 0 High Q8VG01 Olfactory receptor OS=Mus musculus OX=10090 GN=Olfr599 PE=3 SV=1 0.006 2.412 3 1 5 1 315 35.5 8.98 40416470.31 30577057.17 17725575.89 31838015.89 1 1 1 1 regulation of biological process;response to stimulus membrane receptor activity;signal transducer activity "Pf00001, Pf13853" 258726 ENSMUSG00000073950.6 Olfr599 7 Olfactory transduction 0 High Q61466 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 OS=Mus musculus OX=10090 GN=Smarcd1 PE=1 SV=3 0 9.717 12 5 5 5 515 58.2 9.25 74169.40625 13816.02832 1 2 cell organization and biogenesis;regulation of biological process;response to stimulus nucleus protein binding;structural molecule activity "Pf02084, Pf02201" 83797 ENSMUSG00000023018.4 Smarcd1 15 RMTs methylate histone arginines; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 0 High A0A075B5W5 Immunoglobulin heavy variable V1-54 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-54 PE=4 SV=1 0 8.586 34 2 5 2 117 12.7 8.84 2 2 2810395.5 3579963.043 2375656.25 1185306.875 3 3 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000094787.2 12 0 High A0A0G2JGD2 Protein S100-A4 (Fragment) OS=Mus musculus OX=10090 GN=S100a4 PE=1 SV=1 0 5.46 23 1 5 1 78 9.1 5.21 4190.182617 1 Met-loss+Acetyl [N-Term] metal ion binding;protein binding Pf01023 ENSMUSG00000001020.8 3 0 High Q8BW75 Amine oxidase [flavin-containing] B OS=Mus musculus OX=10090 GN=Maob PE=1 SV=4 0 8.761 13 4 5 4 520 58.5 8.29 5570.710449 66703.85938 1 1 metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion catalytic activity;nucleotide binding;protein binding "Pf01593, Pf13450" 109731 ENSMUSG00000040147.14 Maob X Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB "Histidine metabolism; Arginine and proline metabolism; Tryptophan metabolism; Dopaminergic synapse; Drug metabolism - cytochrome P450; Metabolic pathways; Amphetamine addiction; Glycine, serine and threonine metabolism; Cocaine addiction; Alcoholism; Phenylalanine metabolism; Tyrosine metabolism; Serotonergic synapse" 0 High Q8BZ09 Mitochondrial 2-oxodicarboxylate carrier OS=Mus musculus OX=10090 GN=Slc25a21 PE=1 SV=1 0 9.752 12 3 5 3 298 33.2 9.72 60385.19141 19539.33398 1 1 Met-loss+Acetyl [N-Term] transport membrane;mitochondrion transporter activity Pf00153 217593 ENSMUSG00000035472.14 Slc25a21 12 Lysine catabolism 0 High Q8QZR3 Pyrethroid hydrolase Ces2a OS=Mus musculus OX=10090 GN=Ces2a PE=1 SV=1 0 8.091 12 4 5 4 558 61.9 6.16 10996.47559 9998.741211 16193.26416 1 1 2 metabolic process catalytic activity "Pf00135, Pf07859" 102022 ENSMUSG00000055730.16 Ces2a 8 Phase I - Functionalization of compounds Drug metabolism - other enzymes 0 High Q99ME9 Nucleolar GTP-binding protein 1 OS=Mus musculus OX=10090 GN=Gtpbp4 PE=1 SV=3 0.003 3.687 3 2 5 2 634 74.1 9.52 cell differentiation;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;Golgi;membrane;nucleus catalytic activity;nucleotide binding;RNA binding "Pf00009, Pf01926, Pf02421, Pf06858, Pf08155, Pf08477" 69237 ENSMUSG00000021149.7 Gtpbp4 13 Ribosome biogenesis in eukaryotes 0 High Q8VDM4 26S proteasome non-ATPase regulatory subunit 2 OS=Mus musculus OX=10090 GN=Psmd2 PE=1 SV=1 0 12.119 5 3 5 3 908 100.1 5.17 46582.90039 4385.677246 2 1 metabolic process;regulation of biological process membrane;nucleus;proteasome catalytic activity;enzyme regulator activity;protein binding Pf01851 21762 ENSMUSG00000006998.15 Psmd2 16 The role of GTSE1 in G2/M progression after G2 checkpoint; CDT1 association with the CDC6:ORC:origin complex; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Degradation of beta-catenin by the destruction complex; Autodegradation of the E3 ubiquitin ligase COP1; UCH proteinases; MAPK6/MAPK4 signaling; SCF-beta-TrCP mediated degradation of Emi1; CDK-mediated phosphorylation and removal of Cdc6; Separation of Sister Chromatids; SCF(Skp2)-mediated degradation of p27/p21; GLI3 is processed to GLI3R by the proteasome; Ub-specific processing proteases; Regulation of ornithine decarboxylase (ODC); Activation of NF-kappaB in B cells; Degradation of GLI1 by the proteasome; FCERI mediated NF-kB activation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Hedgehog ligand biogenesis; Neutrophil degranulation; Downstream TCR signaling; Autodegradation of Cdh1 by Cdh1:APC/C; Regulation of RAS by GAPs; Interleukin-1 family signaling; Asymmetric localization of PCP proteins; G2/M Checkpoints; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Regulation of PTEN stability and activity; Ubiquitin-dependent degradation of Cyclin D1; NIK-->noncanonical NF-kB signaling; Removal of licensing factors from origins; M/G1 Transition; Interleukin-20 family signaling; Regulation of RUNX2 expression and activity; Cross-presentation of soluble exogenous antigens (endosomes); ABC-family proteins mediated transport; APC/C:Cdc20 mediated degradation of Securin; Regulation of DNA replication; Dectin-1 mediated noncanonical NF-kB signaling; Antigen processing: Ubiquitination & Proteasome degradation; Orc1 removal from chromatin; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of RUNX3 expression and activity; Hedgehog 'on' state; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Degradation of DVL; Degradation of AXIN Proteasome; Epstein-Barr virus infection 0 High A0A075B5W7 Immunoglobulin heavy variable 1-56 OS=Mus musculus OX=10090 GN=Ighv1-56 PE=4 SV=1 0 10.661 19 1 5 1 98 10.8 8.47 43506.30859 76361.98438 284160.2813 1 1 1 Pf07686 ENSMUSG00000094862.2 LOC673634 12 0 High E9Q718 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 OS=Mus musculus OX=10090 GN=Plod2 PE=1 SV=1" 0 8.274 5 4 5 4 758 86.8 6.89 metabolic process;response to stimulus endoplasmic reticulum;membrane catalytic activity;metal ion binding Pf03171 26432 ENSMUSG00000032374.14 Plod2 9 0 High Q99PG0 Arylacetamide deacetylase OS=Mus musculus OX=10090 GN=Aadac PE=1 SV=3 0 9.26 14 4 5 4 398 45.2 7.49 11844.64258 44626.14063 31276.78906 1 1 1 metabolic process;regulation of biological process endoplasmic reticulum;membrane catalytic activity "Pf00326, Pf05448, Pf07859" 67758 ENSMUSG00000027761.4 Aadac 3 Phase I - Functionalization of compounds 0 High Q8BH35 Complement component C8 beta chain OS=Mus musculus OX=10090 GN=C8b PE=1 SV=1 0 11.016 9 4 5 4 589 66.2 7.77 4943.026855 53051.44922 1 1 defense response;metabolic process;regulation of biological process;response to stimulus extracellular protein binding "Pf00057, Pf00090, Pf01823" 110382 ENSMUSG00000029656.13 C8b 4 Regulation of Complement cascade; Terminal pathway of complement Complement and coagulation cascades; Prion diseases; Systemic lupus erythematosus; Amoebiasis 0 High F8WI14 Extracellular matrix protein 1 OS=Mus musculus OX=10090 GN=Ecm1 PE=1 SV=1 0 6.377 7 3 5 3 558 62.7 6.89 24111.3291 6572.244141 7693.802734 2 2 1 defense response;regulation of biological process;response to stimulus extracellular protein binding;signal transducer activity Pf05782 13601 ENSMUSG00000028108.15 Ecm1 3 0 Medium Q8CI17 Protein mab-21-like 3 OS=Mus musculus OX=10090 GN=Mab21L3 PE=2 SV=2 0.012 2.096 4 1 5 1 429 49.7 8.88 1 1 1813360.125 3077276.75 1682273.875 1596055.25 1 1 1 1 Pf03281 242125 ENSMUSG00000044313.13 Mab21l3 3 0 High Q9D8C4 Interferon-induced 35 kDa protein homolog OS=Mus musculus OX=10090 GN=Ifi35 PE=1 SV=3 0 7.053 19 3 5 3 286 31.9 5.87 Met-loss+Acetyl [N-Term] nucleus "Pf07292, Pf07334" 70110 ENSMUSG00000010358.13 Ifi35 11 0 High O89112 Glutathione S-transferase LANCL1 OS=Mus musculus OX=10090 GN=Lancl1 PE=1 SV=1 0 6.206 3 1 5 1 399 45.3 7.77 7925.413574 67949.44873 9675.443359 1 2 2 regulation of biological process;response to stimulus cytoplasm;membrane metal ion binding;protein binding Pf05147 14768 ENSMUSG00000026000.16 Lancl1 1 0 High P54116 Erythrocyte band 7 integral membrane protein OS=Mus musculus OX=10090 GN=Stom PE=1 SV=3 0 7.945 15 3 5 3 284 31.4 6.93 425649.1094 2 cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton;cytosol;endoplasmic reticulum;membrane;mitochondrion protein binding Pf01145 13830 ENSMUSG00000026880.11 Stom 2 Neutrophil degranulation 0 High A0A0N4SUQ1 Plasminogen activator inhibitor 1 RNA-binding protein OS=Mus musculus OX=10090 GN=Serbp1 PE=1 SV=1 0 8.672 33 3 5 3 147 16.1 9.66 111049.627 45779.83984 2 1 Met-loss [N-Term] RNA binding ENSMUSG00000036371.6 6 0 High Q9CQQ7 "ATP synthase F(0) complex subunit B1, mitochondrial OS=Mus musculus OX=10090 GN=Atp5pb PE=1 SV=1" 0 6.255 13 3 5 3 256 28.9 9.06 23406.85742 1 metabolic process;transport membrane;mitochondrion;nucleus catalytic activity;transporter activity Pf05405 11950 ENSMUSG00000000563.17 Atp5f1 3 Cristae formation; Formation of ATP by chemiosmotic coupling Metabolic pathways; Huntington's disease; Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High Q8VC57 BTB/POZ domain-containing protein KCTD5 OS=Mus musculus OX=10090 GN=Kctd5 PE=1 SV=1 0.003 3.328 5 1 5 1 234 26.1 5.95 1 1 65919.53906 67614.63281 35591.78125 1 1 1 cell organization and biogenesis;metabolic process cytoplasm;cytosol protein binding Pf02214 69259 Kctd5 17 0 High P26369 Splicing factor U2AF 65 kDa subunit OS=Mus musculus OX=10090 GN=U2af2 PE=1 SV=3 0 5.684 4 1 5 1 475 53.5 9.09 49723.64063 44648.11621 1 1 metabolic process;regulation of biological process nucleus;spliceosomal complex protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 22185 ENSMUSG00000030435.16 U2af2 7 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript Spliceosome 0 Medium A0A3B2WC92 Spastin OS=Mus musculus OX=10090 GN=Spast PE=1 SV=1 0.011 2.113 3 1 5 1 581 62.7 9.76 0 High P52792 Hexokinase-4 OS=Mus musculus OX=10090 GN=Gck PE=1 SV=1 0 12.62 13 4 5 4 465 52.1 5.29 cell communication;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;mitochondrion;nucleus catalytic activity;enzyme regulator activity;metal ion binding;nucleotide binding;protein binding "Pf00349, Pf03727" 103988 ENSMUSG00000041798.15 Gck 11 Regulation of Glucokinase by Glucokinase Regulatory Protein "Neomycin, kanamycin and gentamicin biosynthesis; Type II diabetes mellitus; Prolactin signaling pathway; Insulin signaling pathway; Metabolic pathways; Maturity onset diabetes of the young; Amino sugar and nucleotide sugar metabolism; Starch and sucrose metabolism; Glycolysis / Gluconeogenesis; Carbon metabolism; Insulin secretion; Galactose metabolism; Central carbon metabolism in cancer; Glucagon signaling pathway" 0 High A3KGR9 Histocompatibility 13 (Fragment) OS=Mus musculus OX=10090 GN=H13 PE=1 SV=1 0 6.229 10 2 5 1 347 38.2 8.4 101191.1621 5420.031738 2 1 metabolic process cell surface;endoplasmic reticulum;membrane catalytic activity;protein binding Pf04258 14950 ENSMUSG00000019188.16 H13 2 1 High Q3TUQ7 Non-specific serine/threonine protein kinase OS=Mus musculus OX=10090 GN=Prkaa1 PE=1 SV=1 0 13.281 11 4 5 4 550 62.7 7.59 46541.30664 8201.249023 3356.477051 2 2 1 cell communication;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00069, Pf07714, Pf14531" 105787 Prkaa1 15 Oxytocin signaling pathway; FoxO signaling pathway; mTOR signaling pathway; Hypertrophic cardiomyopathy (HCM); Insulin signaling pathway; Insulin resistance; Circadian rhythm; Longevity regulating pathway; Non-alcoholic fatty liver disease (NAFLD); Autophagy; Adipocytokine signaling pathway; PI3K-Akt signaling pathway; AMPK signaling pathway; Glucagon signaling pathway; Longevity regulating pathway - multiple species 0 High Q3TJZ6 Protein FAM98A OS=Mus musculus OX=10090 GN=Fam98a PE=1 SV=1 0 6.728 8 3 5 3 515 55 8.95 1 1 54043.56982 149006.9219 2 2 metabolic process;regulation of biological process catalytic activity;protein binding;RNA binding Pf10239 72722 ENSMUSG00000002017.9 Fam98a 17 0 High P08228 Superoxide dismutase [Cu-Zn] OS=Mus musculus OX=10090 GN=Sod1 PE=1 SV=2 0 13.24 16 2 5 2 154 15.9 6.51 2335.676514 118991.2227 22553.47852 1 1 1 cell organization and biogenesis;cellular component movement;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;extracellular;membrane;mitochondrion;nucleus;vacuole antioxidant activity;catalytic activity;metal ion binding;protein binding Pf00080 20655 ENSMUSG00000022982.9 Sod1 16 Platelet degranulation ; Detoxification of Reactive Oxygen Species Amyotrophic lateral sclerosis (ALS); Huntington's disease; Prion diseases; Longevity regulating pathway - multiple species; Peroxisome 0 High Q9Z0K8 Pantetheinase OS=Mus musculus OX=10090 GN=Vnn1 PE=1 SV=3 0 12.587 14 4 5 4 512 57.1 5.94 24291.71729 27041.16016 7002.871582 3 2 1 defense response;metabolic process;regulation of biological process;response to stimulus membrane catalytic activity Pf00795 22361 ENSMUSG00000037440.8 Vnn1 10 Post-translational modification: synthesis of GPI-anchored proteins; Neutrophil degranulation; Vitamin B5 (pantothenate) metabolism Pantothenate and CoA biosynthesis 0 High Q9JMD3 START domain-containing protein 10 OS=Mus musculus OX=10090 GN=Stard10 PE=1 SV=1 0 6.805 15 3 5 3 291 32.9 7.12 58863.71875 12283.08984 1 1 Acetyl [N-Term] regulation of biological process;transport cytoplasm;cytosol;membrane Pf01852 56018 ENSMUSG00000030688.15 Stard10 7 Synthesis of PC 0 High E9PXP7 Stonin-2 OS=Mus musculus OX=10090 GN=Ston2 PE=1 SV=1 0 13.464 8 5 5 5 898 99.8 5.48 regulation of biological process;transport "Pf00928, Pf12016" ENSMUSG00000020961.14 12 0 High E9Q7U2 Calcium-binding and coiled-coil domain-containing protein 1 OS=Mus musculus OX=10090 GN=Calcoco1 PE=1 SV=1 0 9.283 9 4 5 4 633 70.9 4.86 3741.000488 1 cellular component movement;metabolic process;regulation of biological process;response to stimulus catalytic activity;motor activity;protein binding "Pf01576, Pf04111, Pf05667, Pf06008, Pf07888, Pf09789, Pf12128, Pf13514, Pf13851" ENSMUSG00000023055.9 15 0 High Q8C767 Protein phosphatase 1 regulatory subunit 3B OS=Mus musculus OX=10090 GN=Ppp1r3b PE=1 SV=1 0 11.508 20 4 5 4 284 32.4 5.87 2 2 416938.6101 330100.7344 75491.24219 3 2 2 metabolic process;regulation of biological process catalytic activity;enzyme regulator activity;protein binding Pf03370 244416 ENSMUSG00000046794.9 Ppp1r3b 8 Insulin signaling pathway; Insulin resistance 0 High A0A0B4J1I7 Immunoglobulin kappa variable 4-68 (Fragment) OS=Mus musculus OX=10090 GN=Igkv4-68 PE=4 SV=1 0.002 5.079 17 1 5 1 117 12.7 7.96 1 3 1397541.688 165789.2422 1 1 response to stimulus "Pf00047, Pf07686" 384515 ENSMUSG00000076549.2 Igkv4-68 6 0 High O70165 Ficolin-1 OS=Mus musculus OX=10090 GN=Fcn1 PE=1 SV=1 0 7.099 10 3 5 3 334 36.3 6.52 29599.20117 1 defense response;metabolic process;regulation of biological process;response to stimulus extracellular;membrane metal ion binding;protein binding;receptor activity;signal transducer activity "Pf00147, Pf01391, Pf14513" 14133 ENSMUSG00000026938.10 Fcna 2 0 High Q9JII5 DAZ-associated protein 1 OS=Mus musculus OX=10090 GN=Dazap1 PE=1 SV=2 0.002 4.569 4 1 5 1 406 43.2 8.56 27370.84277 53485.58398 5536.179688 2 2 1 cell differentiation;cell proliferation;development;regulation of biological process cytoplasm;cytosol;nucleus RNA binding "Pf00076, Pf13893, Pf14259" 70248 ENSMUSG00000069565.12 Dazap1 10 mRNA surveillance pathway 0 High Q8VCM8 Nicalin OS=Mus musculus OX=10090 GN=Ncln PE=1 SV=2 0 9.143 8 4 5 4 563 62.9 6.49 7445.636719 1712.701904 1 1 metabolic process;regulation of biological process endoplasmic reticulum;membrane "Pf04389, Pf05450" 103425 ENSMUSG00000020238.14 Ncln 10 0 High Q64471 Glutathione S-transferase theta-1 OS=Mus musculus OX=10090 GN=Gstt1 PE=1 SV=4 0.002 4.646 13 3 5 3 240 27.4 7.27 metabolic process;response to stimulus cytoplasm;cytosol;nucleus antioxidant activity;catalytic activity;protein binding "Pf00043, Pf02798, Pf13409, Pf13410, Pf13417, Pf14497" 14871 ENSMUSG00000001663.10 Gstt1 10 Glutathione metabolism; Platinum drug resistance; Drug metabolism - cytochrome P450; Chemical carcinogenesis; Metabolism of xenobiotics by cytochrome P450 0 High F6Q2Y9 Protein transport protein sec16 (Fragment) OS=Mus musculus OX=10090 GN=Sec16b PE=1 SV=2 0 9.298 6 4 5 4 699 77.3 5.47 6583.811035 3734.031738 1 1 cell organization and biogenesis;transport endoplasmic reticulum;Golgi;membrane "Pf12931, Pf12932" ENSMUSG00000026589.14 1 0 High Q9CWY4 Gem-associated protein 7 OS=Mus musculus OX=10090 GN=Gemin7 PE=2 SV=1 0.002 4.113 29 2 5 2 129 14.2 7.52 165157.2188 28086.23047 11797.8916 1 1 1 Acetyl [N-Term] cell organization and biogenesis;metabolic process cytoplasm;cytosol;nucleus protein binding Pf11095 69731 ENSMUSG00000044709.6 Gemin7 7 snRNP Assembly RNA transport 0 High Q9QYI4 DnaJ homolog subfamily B member 12 OS=Mus musculus OX=10090 GN=Dnajb12 PE=1 SV=2 0 8.55 10 3 5 3 376 42 8.51 20804.18164 113256.1152 11189.75098 1 1 1 cell organization and biogenesis;metabolic process;response to stimulus endoplasmic reticulum;membrane;nucleus protein binding "Pf00226, Pf09320" 56709 ENSMUSG00000020109.13 Dnajb12 10 Protein processing in endoplasmic reticulum 0 High Q9QY76 Vesicle-associated membrane protein-associated protein B OS=Mus musculus OX=10090 GN=Vapb PE=1 SV=3 0.002 4.85 11 2 5 1 243 26.9 7.78 26084.23047 91550.00781 36242.37891 1 1 1 cell organization and biogenesis;cellular homeostasis;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;Golgi;membrane protein binding Pf00635 56491 Vapb 2 0 High P01723 Ig lambda-1 chain V region OS=Mus musculus OX=10090 PE=1 SV=2 0.002 4.21 36 2 5 1 117 12.2 5.21 1 1 1 1 3303629 957651.875 203859.3125 1 1 1 response to stimulus membrane Pf07686 16142 Iglv1 16 1 High Q3UDC3 Target of Myb protein 1 OS=Mus musculus OX=10090 GN=Tom1 PE=1 SV=1 0 8.055 10 3 5 3 516 57.1 4.97 Acetyl [N-Term] transport cytoplasm;cytosol;endosome;membrane protein binding "Pf00790, Pf03127" 21968 ENSMUSG00000042870.15 Tom1 8 0 High A0A571BEI2 AP2-associated protein kinase 1 (Fragment) OS=Mus musculus OX=10090 GN=Aak1 PE=1 SV=1 0 11.821 13 4 5 4 510 54 5.01 279205.9063 60570.52295 1 2 0 High Q9Z204 Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Mus musculus OX=10090 GN=Hnrnpc PE=1 SV=1 0 7.249 11 3 5 3 313 34.4 5.05 55791.03052 2 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process cytoskeleton;cytosol;extracellular;membrane;nucleus;spliceosomal complex DNA binding;enzyme regulator activity;protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 15381 ENSMUSG00000060373.14 Hnrnpc 14 mRNA Splicing - Major Pathway; SUMOylation of RNA binding proteins Spliceosome 0 High O35129 Prohibitin-2 OS=Mus musculus OX=10090 GN=Phb2 PE=1 SV=1 0 9.539 16 4 5 4 299 33.3 9.83 77003.71777 40562.13477 10997.7168 62180.88916 4 2 1 3 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;membrane;mitochondrion;nucleus protein binding Pf01145 12034 ENSMUSG00000004264.17 Phb2 6 Processing of SMDT1 0 High Q8K2C9 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Mus musculus OX=10090 GN=Hacd3 PE=1 SV=2 0 14.393 13 3 5 3 362 43.1 9.13 20140.28906 32092.16602 1 1 Acetyl [N-Term] metabolic process;regulation of biological process;response to stimulus cytosol;endoplasmic reticulum;membrane;mitochondrion catalytic activity;protein binding "Pf04387, Pf04969" 57874 ENSMUSG00000033629.6 Ptplad1; Hacd3 9 Fatty acid metabolism; Fatty acid elongation; Biosynthesis of unsaturated fatty acids 0 High Q64374 Regucalcin OS=Mus musculus OX=10090 GN=Rgn PE=1 SV=1 0 8.479 15 3 5 3 299 33.4 5.34 13484.96631 2 cellular homeostasis;metabolic process;regulation of biological process cytoplasm;cytosol;extracellular;nucleus catalytic activity;enzyme regulator activity;metal ion binding Pf08450 19733 ENSMUSG00000023070.6 Rgn X Metabolic pathways; Pentose phosphate pathway; Ascorbate and aldarate metabolism; Carbon metabolism 0 High Q91WL5 Cytochrome P450 4A12A OS=Mus musculus OX=10090 GN=Cyp4a12a PE=1 SV=2 0 10.553 10 4 5 4 508 58.3 9.13 57762.90039 12340.7207 15215.78711 3739.531494 2 1 1 1 metabolic process endoplasmic reticulum;membrane catalytic activity;metal ion binding Pf00067 277753 ENSMUSG00000066071.6 Cyp4a12a 4 Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE); Fatty acids PPAR signaling pathway; Retinol metabolism; Metabolic pathways; Fatty acid degradation; Vascular smooth muscle contraction; Arachidonic acid metabolism; Inflammatory mediator regulation of TRP channels 0 High Q99P30 Peroxisomal coenzyme A diphosphatase NUDT7 OS=Mus musculus OX=10090 GN=Nudt7 PE=1 SV=2 0 10.127 15 3 5 3 236 26.8 6.34 4657.46875 107488.6797 177357.5 1 1 1 Met-loss+Acetyl [N-Term] cell differentiation;metabolic process catalytic activity;metal ion binding;protein binding;RNA binding Pf00293 67528 ENSMUSG00000031767.13 Nudt7 8 Peroxisomal lipid metabolism Peroxisome 0 High V9GXX7 DNA repair protein SWI5 homolog (Fragment) OS=Mus musculus OX=10090 GN=Swi5 PE=1 SV=1 0 12.283 26 3 5 3 140 16.1 6.02 61479.83887 6279.088867 6749.293457 2 1 1 metabolic process "Pf04111, Pf07061" ENSMUSG00000044627.11 2 0 High Q569X9 "Cytochrome P450, family 2, subfamily c, polypeptide 67 OS=Mus musculus OX=10090 GN=Cyp2c67 PE=1 SV=1" 0 8.772 8 3 5 1 491 56.1 7.36 metabolic process catalytic activity;metal ion binding Pf00067 545288 ENSMUSG00000062624.5 Cyp2c67 19 0 High B7ZNL2 Nap1l4 protein OS=Mus musculus OX=10090 GN=Nap1l4 PE=1 SV=1 0 6.35 7 2 4 1 386 43.9 4.68 cell organization and biogenesis cytoplasm;nucleus protein binding;RNA binding Pf00956 17955 ENSMUSG00000059119.9 Nap1l4 7 0 Medium A0A0G2JGN4 Small nuclear ribonucleoprotein-associated protein B OS=Mus musculus OX=10090 GN=Snrpb PE=4 SV=1 0.013 1.983 10 1 4 1 70 8.4 9.07 21977.36719 46371.03516 43190.98047 52818.88672 1 1 1 1 regulation of biological process "Pf01423, Pf03614" ENSMUSG00000027404.15 2 0 High P10922 Histone H1.0 OS=Mus musculus OX=10090 GN=H1-0 PE=2 SV=4 0.002 4.574 7 1 4 1 194 20.8 10.9 64815.9375 50775.59766 36902.16406 1 1 1 cell organization and biogenesis chromosome;cytoskeleton;Golgi;nucleus DNA binding;RNA binding Pf00538 14958 ENSMUSG00000096210.1 H1f0 15 Activation of DNA fragmentation factor; Formation of Senescence-Associated Heterochromatin Foci (SAHF) 0 High Q80UW8 "DNA-directed RNA polymerases I, II, and III subunit RPABC1 OS=Mus musculus OX=10090 GN=Polr2e PE=1 SV=1" 0 7.118 11 2 4 2 210 24.6 5.95 18945.20703 5836.57666 71239.38281 1 1 2 metabolic process nucleus catalytic activity;DNA binding "Pf01191, Pf03871" 66420 ENSMUSG00000004667.18 Polr2e 10 mRNA Capping; RNA Polymerase II Transcription Initiation; Transcriptional regulation by small RNAs; RNA Polymerase II Pre-transcription Events; RNA Polymerase I Transcription Termination; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Formation of RNA Pol II elongation complex ; mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; RNA Pol II CTD phosphorylation and interaction with CE; FGFR2 alternative splicing; RNA Polymerase I Transcription Initiation; B-WICH complex positively regulates rRNA expression; mRNA Splicing - Minor Pathway; RNA Polymerase III Transcription Initiation From Type 1 Promoter; Dual incision in TC-NER; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA polymerase II transcribes snRNA genes; Formation of the Early Elongation Complex; TP53 Regulates Transcription of DNA Repair Genes; RNA Polymerase I Promoter Escape; Gap-filling DNA repair synthesis and ligation in TC-NER; RNA Polymerase I Chain Elongation; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA polymerase; Epstein-Barr virus infection; Metabolic pathways; Purine metabolism; Huntington's disease; Pyrimidine metabolism; Cytosolic DNA-sensing pathway 0 High P08122 Collagen alpha-2(IV) chain OS=Mus musculus OX=10090 GN=Col4a2 PE=1 SV=4 0 7.21 2 3 4 3 1707 167.2 8.48 2 2 269552.6504 16256.63867 3 1 cell differentiation;metabolic process;regulation of biological process;response to stimulus extracellular structural molecule activity "Pf01391, Pf01413" 12827 ENSMUSG00000031503.13 Col4a2 8 Anchoring fibril formation; Laminin interactions; Crosslinking of collagen fibrils; Collagen chain trimerization; Integrin cell surface interactions; NCAM1 interactions; Collagen degradation; Non-integrin membrane-ECM interactions; Signaling by PDGF AGE-RAGE signaling pathway in diabetic complications; Focal adhesion; Protein digestion and absorption; Small cell lung cancer; Pathways in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway; Amoebiasis 0 High Q9WUM3 Coronin-1B OS=Mus musculus OX=10090 GN=Coro1b PE=1 SV=1 0 7.114 7 3 4 3 484 53.9 5.78 43825.95313 1 cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane protein binding "Pf00400, Pf08953, Pf08954" 23789 ENSMUSG00000024835.14; ENSMUSG00000097771.7 Coro1b 19; CHR_MG153_PATCH 0 High Q9JJA4 Ribosome biogenesis protein WDR12 OS=Mus musculus OX=10090 GN=Wdr12 PE=1 SV=1 0 6.585 11 4 4 4 423 47.3 5.6 42981.44482 4 cell proliferation;metabolic process;regulation of biological process;response to stimulus nucleus protein binding "Pf00400, Pf08154" 57750 ENSMUSG00000026019.15 Wdr12 1 Major pathway of rRNA processing in the nucleolus and cytosol 0 High Q64691 Calpain-3 OS=Mus musculus OX=10090 GN=Capn3 PE=1 SV=2 0 7.51 5 3 4 3 821 94.2 6.14 3 4 3291.465576 797852.7031 52395.40039 14017.61523 1 2 1 1 cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;nucleus catalytic activity;enzyme regulator activity;metal ion binding;protein binding;structural molecule activity "Pf00036, Pf00648, Pf01067, Pf13405, Pf13499, Pf13833" 12335 ENSMUSG00000079110.11 Capn3 2 0 High Q811S7 Upstream-binding protein 1 OS=Mus musculus OX=10090 GN=Ubp1 PE=1 SV=1 0 7.412 10 3 4 3 540 60.2 6.27 29863.96826 553398.5625 8350.198242 2 1 1 metabolic process;regulation of biological process cytosol;nucleus DNA binding Pf04516 22221 ENSMUSG00000009741.15 Ubp1 9 0 High Q9CYI4 Putative RNA-binding protein Luc7-like 1 OS=Mus musculus OX=10090 GN=Luc7l PE=1 SV=2 0 5.786 13 4 4 2 371 43.9 9.88 21311.34375 33345.59375 1 1 cell organization and biogenesis;regulation of biological process nucleus;spliceosomal complex protein binding;RNA binding Pf03194 66978 ENSMUSG00000024188.15 Luc7l 17 0 High A0A2R8W6R3 E3 ubiquitin-protein ligase RBX1 OS=Mus musculus OX=10090 GN=Rbx1 PE=1 SV=1 0 6.803 24 2 4 2 83 9.1 5.8 69692.10938 1 Met-loss+Acetyl [N-Term] 0 High A2BDX2 Dolichol-phosphate mannosyltransferase subunit 1 OS=Mus musculus OX=10090 GN=Dpm1 PE=1 SV=1 0 12.402 27 4 4 4 208 23.4 9.31 13330.04199 362817.5313 31621.97852 1 1 1 metabolic process endoplasmic reticulum;membrane;nucleus catalytic activity "Pf00535, Pf10111, Pf13641, Pf13704, Pf13712" 13480 ENSMUSG00000078919.10 Dpm1 2 0 Medium O35226 26S proteasome non-ATPase regulatory subunit 4 OS=Mus musculus OX=10090 GN=Psmd4 PE=1 SV=1 0.013 1.996 5 1 4 1 376 40.7 4.79 cell organization and biogenesis;metabolic process cytoplasm;cytosol;nucleus;proteasome protein binding;RNA binding "Pf02809, Pf04056, Pf13519" 19185 ENSMUSG00000005625.15 Psmd4 3 The role of GTSE1 in G2/M progression after G2 checkpoint; CDT1 association with the CDC6:ORC:origin complex; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Degradation of beta-catenin by the destruction complex; Autodegradation of the E3 ubiquitin ligase COP1; UCH proteinases; MAPK6/MAPK4 signaling; SCF-beta-TrCP mediated degradation of Emi1; CDK-mediated phosphorylation and removal of Cdc6; Separation of Sister Chromatids; SCF(Skp2)-mediated degradation of p27/p21; GLI3 is processed to GLI3R by the proteasome; Ub-specific processing proteases; Regulation of ornithine decarboxylase (ODC); Activation of NF-kappaB in B cells; FCERI mediated NF-kB activation; Degradation of GLI1 by the proteasome; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Hedgehog ligand biogenesis; Downstream TCR signaling; Autodegradation of Cdh1 by Cdh1:APC/C; Regulation of RAS by GAPs; Interleukin-1 family signaling; Asymmetric localization of PCP proteins; G2/M Checkpoints; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Regulation of PTEN stability and activity; Ubiquitin-dependent degradation of Cyclin D1; NIK-->noncanonical NF-kB signaling; Removal of licensing factors from origins; M/G1 Transition; Interleukin-20 family signaling; Regulation of RUNX2 expression and activity; Cross-presentation of soluble exogenous antigens (endosomes); ABC-family proteins mediated transport; APC/C:Cdc20 mediated degradation of Securin; Regulation of DNA replication; Dectin-1 mediated noncanonical NF-kB signaling; Antigen processing: Ubiquitination & Proteasome degradation; Orc1 removal from chromatin; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of RUNX3 expression and activity; Hedgehog 'on' state; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Degradation of DVL; Degradation of AXIN Proteasome; Epstein-Barr virus infection 0 High A0A0R4J1Q0 Enhancer of mRNA-decapping protein 4 OS=Mus musculus OX=10090 GN=Edc4 PE=1 SV=1 0.002 4.186 2 2 4 2 1390 150.6 5.68 20658.4375 2 metabolic process cytoplasm;membrane;nucleus protein binding Pf00400 234699 ENSMUSG00000036270.16 Edc4 8 mRNA decay by 5' to 3' exoribonuclease 0 High Q4FZF3 Probable ATP-dependent RNA helicase DDX49 OS=Mus musculus OX=10090 GN=Ddx49 PE=2 SV=1 0.006 2.391 2 1 4 1 480 54.1 8.78 metabolic process cytoplasm catalytic activity;nucleotide binding;RNA binding "Pf00270, Pf00271" 234374 ENSMUSG00000057788.13 Ddx49 8 Major pathway of rRNA processing in the nucleolus and cytosol 0 High Q91ZJ5 UTP--glucose-1-phosphate uridylyltransferase OS=Mus musculus OX=10090 GN=Ugp2 PE=1 SV=3 0.002 4.02 3 2 4 2 508 56.9 7.61 15405.48145 4623.832031 15287.01563 2 1 2 metabolic process cytoplasm;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding Pf01704 216558 ENSMUSG00000001891.16 Ugp2 11 "Formation of the active cofactor, UDP-glucuronate; Glycogen synthesis" Metabolic pathways; Amino sugar and nucleotide sugar metabolism; Starch and sucrose metabolism; Pentose and glucuronate interconversions; Galactose metabolism 0 High Q6ZQL4 WD repeat-containing protein 43 OS=Mus musculus OX=10090 GN=Wdr43 PE=1 SV=2 0 7.51 9 4 4 4 677 75.3 5.38 metabolic process;regulation of biological process nucleus protein binding;RNA binding "Pf00400, Pf04003" 72515 ENSMUSG00000041057.9 Wdr43 17 Major pathway of rRNA processing in the nucleolus and cytosol Ribosome biogenesis in eukaryotes 0 High Q9EQY0 Serine/threonine-protein kinase/endoribonuclease IRE1 OS=Mus musculus OX=10090 GN=Ern1 PE=1 SV=1 0 8.566 6 4 4 4 977 110.1 6.51 251368.0693 22930.30176 19507.38867 43270.53516 3 2 1 1 cell death;cell proliferation;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cytoplasm;endoplasmic reticulum;membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00069, Pf06479, Pf07714, Pf13360" 78943 ENSMUSG00000020715.9 Ern1 11 IRE1alpha activates chaperones Non-alcoholic fatty liver disease (NAFLD); Alzheimer's disease; Protein processing in endoplasmic reticulum; Apoptosis 0 High Q9DCY0 Glycine N-acyltransferase-like protein Keg1 OS=Mus musculus OX=10090 GN=Keg1 PE=1 SV=1 0 8.65 13 3 4 3 295 33.7 8.43 5415.726074 1 cytoplasm;cytoskeleton;mitochondrion catalytic activity "Pf06021, Pf08444" 64697 ENSMUSG00000024694.9 Keg1 19 Phenylalanine metabolism 0 High A0A087WQ94 Tensin 1 (Fragment) OS=Mus musculus OX=10090 GN=Tns1 PE=1 SV=1 0.002 4.832 3 3 4 3 1719 183.3 7.49 1 1 136423.0908 24818.7207 50178.12842 3 1 3 cell organization and biogenesis;cellular component movement protein binding;RNA binding "Pf00017, Pf08416, Pf10409" ENSMUSG00000055322.15 1 0 High Q61425 "Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Hadh PE=1 SV=2" 0 6.107 12 3 4 3 314 34.4 8.65 2 1 2 1 479366.4922 318541.1719 134238.5703 63467.22656 3 2 2 2 metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf00070, Pf00725, Pf01266, Pf02737, Pf13450" 15107 ENSMUSG00000027984.8 Hadh 3 Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA "Fatty acid metabolism; Tryptophan metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Lysine degradation; Fatty acid degradation; Butanoate metabolism; Fatty acid elongation" 0 High P85094 Isochorismatase domain-containing protein 2A OS=Mus musculus OX=10090 GN=Isoc2a PE=1 SV=1 0.002 4.517 24 2 4 2 206 22.4 8.02 2 1 3 1 510211.4844 134936.7813 229761.3125 128183.8633 2 1 2 2 metabolic process;regulation of biological process cytoplasm;mitochondrion;nucleus catalytic activity Pf00857 664994 ENSMUSG00000086784.2 Isoc2a 7 0 High Q91WU0 Carboxylesterase 1F OS=Mus musculus OX=10090 GN=Ces1f PE=1 SV=1 0 9.803 7 3 4 1 561 61.6 6.48 232726.8438 1 metabolic process cytoplasm;cytosol;endoplasmic reticulum catalytic activity "Pf00135, Pf00326, Pf00756, Pf07859, Pf12695" 234564 ENSMUSG00000031725.8 Ces1f 8 Phase I - Functionalization of compounds 0 High A2A6K0 "Troponin I, fast skeletal muscle (Fragment) OS=Mus musculus OX=10090 GN=Tnni2 PE=1 SV=1" 0 12.577 44 3 4 3 135 15.7 8.57 9370.994141 1 regulation of biological process nucleus metal ion binding;protein binding Pf00992 21953 ENSMUSG00000031097.15 Tnni2 7 0 High P16331 Phenylalanine-4-hydroxylase OS=Mus musculus OX=10090 GN=Pah PE=1 SV=4 0 7.243 8 3 4 3 453 51.9 6.3 125029.1133 184876.9219 52631.78906 53716.36328 1 1 1 1 metabolic process catalytic activity;metal ion binding;protein binding "Pf00351, Pf01842" 18478 ENSMUSG00000020051.17 Pah 10 Phenylalanine and tyrosine catabolism "Metabolic pathways; Phenylalanine, tyrosine and tryptophan biosynthesis; Biosynthesis of amino acids; Phenylalanine metabolism" 0 Medium Q3TCN2 Putative phospholipase B-like 2 OS=Mus musculus OX=10090 GN=Plbd2 PE=1 SV=2 0.018 1.818 1 1 4 1 594 66.2 6.13 39590.78906 169832.3594 118822.6719 1 1 1 metabolic process organelle lumen;vacuole catalytic activity Pf04916 71772 ENSMUSG00000029598.12 Plbd2 5 0 High Q61171 Peroxiredoxin-2 OS=Mus musculus OX=10090 GN=Prdx2 PE=1 SV=3 0 5.77 18 3 4 3 198 21.8 5.41 79860.59375 27454.53906 24790.44141 101526.2598 2 1 1 3 cell proliferation;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;mitochondrion antioxidant activity;catalytic activity;protein binding "Pf00578, Pf08534, Pf10417" 21672 ENSMUSG00000005161.15 Prdx2 8 Detoxification of Reactive Oxygen Species; TP53 Regulates Metabolic Genes 0 High Q3TAQ9 WD repeat domain 36 OS=Mus musculus OX=10090 GN=Wdr36 PE=1 SV=1 0 7.762 4 3 4 3 899 99.7 7.11 metabolic process;regulation of biological process protein binding;RNA binding "Pf00400, Pf04192" 225348 ENSMUSG00000038299.15 Wdr36 18 Major pathway of rRNA processing in the nucleolus and cytosol Ribosome biogenesis in eukaryotes 0 High Q9QYB5 Gamma-adducin OS=Mus musculus OX=10090 GN=Add3 PE=1 SV=2 0 8.074 7 3 4 3 706 78.7 5.95 63063.20898 20777.4585 8776.512451 2 2 2 Met-loss+Acetyl [N-Term] response to stimulus chromosome;cytoplasm;cytoskeleton;membrane protein binding;structural molecule activity Pf00596 27360 ENSMUSG00000025026.14 Add3 19 Miscellaneous transport and binding events 0 High H7BWY3 "Alanine--glyoxylate aminotransferase 2, mitochondrial OS=Mus musculus OX=10090 GN=Agxt2 PE=1 SV=1" 0 5.505 7 3 4 3 541 60.1 7.9 1438.737183 1 metabolic process;regulation of biological process mitochondrion catalytic activity;protein binding "Pf00155, Pf00202" 268782 ENSMUSG00000089678.8 Agxt2 15 0 High O70472 Transmembrane protein 131 OS=Mus musculus OX=10090 GN=Tmem131 PE=2 SV=2 0 10.243 2 4 4 4 1877 204.5 8.54 20710.99805 13279.9873 48112.00977 1 1 3 membrane Pf12371 56030 ENSMUSG00000026116.11 Tmem131 1 0 High P04186 Complement factor B OS=Mus musculus OX=10090 GN=Cfb PE=1 SV=2 0.002 5.155 5 2 4 2 761 85 7.37 7530.368164 43434.03687 29424.16992 1 2 1 cell proliferation;defense response;metabolic process;regulation of biological process;response to stimulus extracellular catalytic activity "Pf00084, Pf00089, Pf00092, Pf13519" 14962 ENSMUSG00000090231.10 Cfb 17 Regulation of Complement cascade; Alternative complement activation; Activation of C3 and C5 0 High Q9QZB7 Actin-related protein 10 OS=Mus musculus OX=10090 GN=Actr10 PE=1 SV=2 0.002 4.514 4 1 4 1 417 46.2 7.61 cellular component movement cytoplasm;cytoskeleton protein binding Pf00022 56444 ENSMUSG00000021076.5 Actr10 12 COPI-independent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; MHC class II antigen presentation; Neutrophil degranulation; HSP90 chaperone cycle for steroid hormone receptors (SHR) 0 High P84228 Histone H3.2 OS=Mus musculus OX=10090 GN=H3c2 PE=1 SV=2 0.005 3.135 29 2 4 2 136 15.4 11.27 191728.6719 1 cell organization and biogenesis;regulation of biological process chromosome;membrane;nucleus DNA binding;protein binding Pf00125 319149; 260423; 15077; 319154; 97114; 319148; 319151; 319150 ENSMUSG00000081058.5; ENSMUSG00000093769.4; ENSMUSG00000074403.2; ENSMUSG00000100210.1; ENSMUSG00000069273.2; ENSMUSG00000099583.1; ENSMUSG00000069310.3; ENSMUSG00000069267.2 Hist1h3d; Hist1h3f; Hist2h3c1; Hist2h3b; Hist2h3c2; Hist1h3c; Hist1h3e; Hist1h3b 13; 3 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Transcriptional regulation by small RNAs; Interleukin-7 signaling; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HATs acetylate histones; Oxidative Stress Induced Senescence; Meiotic Recombination; Senescence-Associated Secretory Phenotype (SASP); HDMs demethylate histones; PRC2 methylates histones and DNA; SIRT1 negatively regulates rRNA expression; B-WICH complex positively regulates rRNA expression; RNA Polymerase I Promoter Opening; NoRC negatively regulates rRNA expression; Meiotic Synapsis; RMTs methylate histone arginines; PKMTs methylate histone lysines; Mus musculus biological processes; RNA Polymerase I Chain Elongation; NoRC negatively regulates rRNA expression; Factors involved in megakaryocyte development and platelet production Transcriptional misregulation in cancer; Alcoholism; Systemic lupus erythematosus 0 High Q8BJT9 ER degradation-enhancing alpha-mannosidase-like protein 2 OS=Mus musculus OX=10090 GN=Edem2 PE=1 SV=1 0 8.339 9 3 4 3 577 64.6 5.55 13839.25293 66740.16113 1 3 metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;membrane catalytic activity;metal ion binding;protein binding Pf01532 108687 ENSMUSG00000038312.10 Edem2 2 ER Quality Control Compartment (ERQC) Protein processing in endoplasmic reticulum 0 High P56379 "ATP synthase subunit ATP5MPL, mitochondrial OS=Mus musculus OX=10090 GN=Atp5mpl PE=1 SV=1" 0.002 4.146 34 2 4 2 58 6.7 9.99 2446.670654 17556.56055 14661.93652 1 1 1 membrane;mitochondrion Pf08039 70257 ENSMUSG00000021290.5 2010107E04Rik 12 0 High Q9D0D4 Probable dimethyladenosine transferase OS=Mus musculus OX=10090 GN=Dimt1 PE=2 SV=1 0 5.366 7 2 4 2 313 35.3 9.99 20227.69336 1 metabolic process;regulation of biological process cytosol;nucleus;organelle lumen catalytic activity;RNA binding "Pf00398, Pf13659" 66254 ENSMUSG00000021692.8 Dimt1 13 0 High P01887 Beta-2-microglobulin OS=Mus musculus OX=10090 GN=B2m PE=1 SV=2 0 5.533 16 2 4 2 119 13.8 8.44 24978.18262 19408.62109 25291.51367 2 1 1 cell differentiation;defense response;metabolic process;regulation of biological process;response to stimulus;transport cytosol;extracellular;Golgi;membrane protein binding Pf07654 12010 ENSMUSG00000060802.8 B2m 2 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Endosomal/Vacuolar pathway; Neutrophil degranulation; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; ER-Phagosome pathway; DAP12 signaling" Antigen processing and presentation 0 High Q01320 DNA topoisomerase 2-alpha OS=Mus musculus OX=10090 GN=Top2a PE=1 SV=2 0.003 3.661 1 2 4 2 1528 172.7 8.6 cell differentiation;cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus chromosome;nucleus catalytic activity;DNA binding;metal ion binding;nucleotide binding;protein binding;RNA binding "Pf00204, Pf00521, Pf01751, Pf02449, Pf02518, Pf08070" 21973 ENSMUSG00000020914.17 Top2a 11 SUMOylation of DNA replication proteins Platinum drug resistance 0 High Q920E5 Farnesyl pyrophosphate synthase OS=Mus musculus OX=10090 GN=Fdps PE=1 SV=1 0 12.148 12 3 4 3 353 40.6 5.66 51860.67969 1 metabolic process;regulation of biological process cytoplasm;cytosol;mitochondrion;organelle lumen catalytic activity;metal ion binding;RNA binding Pf00348 110196 ENSMUSG00000059743.12 Fdps 3 Cholesterol biosynthesis Metabolic pathways; Terpenoid backbone biosynthesis; HTLV-I infection; Influenza A 0 High A0A0R4J0D3 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Mus musculus OX=10090 GN=Stt3b PE=1 SV=1 0 6.843 4 3 4 2 823 93.3 9 111142.6289 2 metabolic process;response to stimulus endoplasmic reticulum;membrane catalytic activity;metal ion binding "Pf02516, Pf13231" 68292 ENSMUSG00000032437.10 Stt3b 9 Metabolic pathways; N-Glycan biosynthesis; Protein processing in endoplasmic reticulum 0 High Q05685 Folate receptor beta OS=Mus musculus OX=10090 GN=Folr2 PE=2 SV=1 0 9.261 9 2 4 2 251 28.8 7.55 cell organization and biogenesis;regulation of biological process;transport cell surface;membrane transporter activity Pf03024 14276 ENSMUSG00000032725.10 Folr2 7 Post-translational modification: synthesis of GPI-anchored proteins; Metabolism of folate and pterines Endocytosis; Antifolate resistance 0 High O88441 Metaxin-2 OS=Mus musculus OX=10090 GN=Mtx2 PE=1 SV=1 0.002 4.887 16 2 4 2 263 29.7 5.63 15419.7002 12211.97949 61924.37451 1 1 2 Met-loss+Acetyl [N-Term] transport membrane;mitochondrion "Pf11801, Pf13410, Pf14497" 53375 ENSMUSG00000027099.9 Mtx2 2 0 High Q3TLP8 Ras-related C3 botulinum toxin substrate 1 OS=Mus musculus OX=10090 GN=Rac1 PE=1 SV=1 0 6.721 16 4 4 4 211 23.4 8.69 13387.87988 14434.1416 1 1 cell communication;cell differentiation;cell organization and biogenesis;cell proliferation;cellular component movement;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;membrane;nucleus catalytic activity;nucleotide binding;protein binding "Pf00025, Pf00071, Pf08477" 19353 ENSMUSG00000001847.14 Rac1 5 0 High P60867 40S ribosomal protein S20 OS=Mus musculus OX=10090 GN=Rps20 PE=1 SV=1 0.002 4.308 16 2 4 2 119 13.4 9.94 19640.26953 16953.1543 28691.97461 1 1 1 metabolic process cytoplasm;membrane;ribosome RNA binding;structural molecule activity Pf00338 67427 ENSMUSG00000028234.6 Rps20 4 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High P22315 "Ferrochelatase, mitochondrial OS=Mus musculus OX=10090 GN=Fech PE=1 SV=2" 0 6.152 9 3 4 3 420 47.1 8.91 14523.34375 64221.28516 2 1 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion catalytic activity;metal ion binding;protein binding;RNA binding Pf00762 14151 Fech 18 0 High Q920A5 Retinoid-inducible serine carboxypeptidase OS=Mus musculus OX=10090 GN=Scpep1 PE=1 SV=2 0.002 4.039 6 2 4 2 452 50.9 5.66 metabolic process cytosol;extracellular catalytic activity Pf00450 74617 ENSMUSG00000000278.10 Scpep1 11 0 High Q61820 "GTP-binding nuclear protein Ran, testis-specific isoform OS=Mus musculus OX=10090 GN=Rasl2-9 PE=2 SV=1" 0.002 4.027 12 2 4 2 216 24.4 6.54 19419.01953 1 Met-loss+Acetyl [N-Term] regulation of biological process;response to stimulus;transport cytoplasm;nucleus catalytic activity;nucleotide binding "Pf00025, Pf00071, Pf01926, Pf04670, Pf08477" 19428 ENSMUSG00000083649.5 Rasl2-9 7 Transcriptional regulation by small RNAs; Regulation of cholesterol biosynthesis by SREBP (SREBF) Epstein-Barr virus infection; HTLV-I infection; Ribosome biogenesis in eukaryotes; RNA transport 0 High Q69ZR2 E3 ubiquitin-protein ligase HECTD1 OS=Mus musculus OX=10090 GN=Hectd1 PE=1 SV=2 0 6.259 1 3 4 3 2618 289.9 5.41 5420.935547 17311.59961 8303.685547 1 1 1 cell differentiation;metabolic process;regulation of biological process cytoplasm catalytic activity;metal ion binding;protein binding "Pf00023, Pf00632, Pf00754, Pf06701, Pf07738, Pf12796, Pf13606, Pf13637, Pf13857" 207304 ENSMUSG00000035247.16 Hectd1 12 0 Medium P03930 ATP synthase protein 8 OS=Mus musculus OX=10090 GN=Mtatp8 PE=1 SV=1 0.018 1.805 15 1 4 1 67 7.8 9.88 24277.20508 12624.73926 18504.89453 1 1 1 metabolic process;response to stimulus;transport membrane;mitochondrion catalytic activity;transporter activity Pf00895 17706; 3338900 ENSMUSG00000064356.3 ATP8 MT Cristae formation; Formation of ATP by chemiosmotic coupling Metabolic pathways; Huntington's disease; Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High Q9QYI3 DnaJ homolog subfamily C member 7 OS=Mus musculus OX=10090 GN=Dnajc7 PE=1 SV=2 0 7.846 7 3 4 3 494 56.4 6.49 2519.899414 1 metabolic process cytoplasm;cytoskeleton;cytosol;membrane;nucleus protein binding "Pf00226, Pf00515, Pf07719, Pf13414, Pf13424, Pf13431, Pf13432, Pf14559" 56354 ENSMUSG00000014195.15 Dnajc7 11 0 High Q91ZA3 "Propionyl-CoA carboxylase alpha chain, mitochondrial OS=Mus musculus OX=10090 GN=Pcca PE=1 SV=2" 0 9.177 8 4 4 4 724 79.9 7.25 1 1 166753.0664 363753.8281 77631.82227 3 3 3 extracellular;mitochondrion;organelle lumen catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00289, Pf00364, Pf01071, Pf02222, Pf02258, Pf02785, Pf02786, Pf07478, Pf08442, Pf13533, Pf13535, Pf13549, Pf15632" 110821 ENSMUSG00000041650.15 Pcca 14 Propionyl-CoA catabolism; Biotin transport and metabolism "Valine, leucine and isoleucine degradation; Metabolic pathways; Propanoate metabolism; Carbon metabolism; Glyoxylate and dicarboxylate metabolism" 0 Medium P97463 Neurturin OS=Mus musculus OX=10090 GN=Nrtn PE=1 SV=1 0.031 1.508 4 1 4 1 195 22.2 10.92 8571.693359 2943.817871 9215.461914 7346.520508 1 1 1 1 cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus extracellular protein binding Pf00019 18188 ENSMUSG00000039481.5 Nrtn 17 RET signaling; RAF/MAP kinase cascade; Interleukin-20 family signaling 0 High P70698 CTP synthase 1 OS=Mus musculus OX=10090 GN=Ctps1 PE=1 SV=2 0 9.102 8 4 4 4 591 66.6 6.58 3846.252197 1 cell proliferation;metabolic process membrane catalytic activity;nucleotide binding;protein binding "Pf00117, Pf06418, Pf07722" 51797 ENSMUSG00000028633.7 Ctps 4 Interconversion of nucleotide di- and triphosphates Metabolic pathways; Pyrimidine metabolism 0 High Q9CR14 E3 ubiquitin-protein ligase FANCL OS=Mus musculus OX=10090 GN=Fancl PE=1 SV=1 0 8.681 9 3 4 3 375 42.5 6.52 2376.898438 24328.08203 1 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus catalytic activity;metal ion binding;protein binding "Pf09765, Pf11793, Pf12861" 67030 ENSMUSG00000004018.9 Fancl 11 Fanconi Anemia Pathway Ubiquitin mediated proteolysis; Fanconi anemia pathway 0 High J3QNY6 Bile salt export pump OS=Mus musculus OX=10090 GN=Abcb11 PE=1 SV=1 0 8.834 3 3 4 3 1321 146.7 7.46 transport membrane catalytic activity;nucleotide binding;transporter activity "Pf00005, Pf00664" ENSMUSG00000027048.15 2 0 High P70699 Lysosomal alpha-glucosidase OS=Mus musculus OX=10090 GN=Gaa PE=1 SV=2 0 6.249 3 3 4 3 953 106.2 5.83 2327.115234 14033.4873 1 1 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus membrane;vacuole catalytic activity "Pf00088, Pf01055, Pf13802" 14387 ENSMUSG00000025579.14 Gaa 11 Glycogen breakdown (glycogenolysis); Neutrophil degranulation; Lysosomal glycogen catabolism Metabolic pathways; Lysosome; Starch and sucrose metabolism; Galactose metabolism 0 High Q61937 Nucleophosmin OS=Mus musculus OX=10090 GN=Npm1 PE=1 SV=1 0 7.982 12 2 4 2 292 32.5 4.77 10533.0293 64732.36719 30400.65234 28316.79688 1 1 1 1 cell growth;cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;membrane;nucleus DNA binding;enzyme regulator activity;nucleotide binding;protein binding;RNA binding Pf03066 18148 ENSMUSG00000057113.13 Npm1 11 0 High Q3UNH6 Cyclic AMP-responsive element-binding protein 3 OS=Mus musculus OX=10090 GN=Creb3 PE=2 SV=1 0 6.94 10 3 4 3 379 42.4 4.98 8820.238281 30775.28809 2 2 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;endoplasmic reticulum;Golgi;membrane;nucleus DNA binding;protein binding "Pf00170, Pf03131, Pf07716" 12913 ENSMUSG00000028466.15 Creb3 4 CREB3 factors activate genes Cholinergic synapse; Dopaminergic synapse; TNF signaling pathway; Amphetamine addiction; Insulin resistance; Melanogenesis; Hepatitis B; Thyroid hormone synthesis; Longevity regulating pathway; Huntington's disease; Cocaine addiction; cGMP-PKG signaling pathway; Alcoholism; PI3K-Akt signaling pathway; cAMP signaling pathway; AMPK signaling pathway; Aldosterone synthesis and secretion; Vasopressin-regulated water reabsorption; Insulin secretion; Estrogen signaling pathway; Glucagon signaling pathway; Viral carcinogenesis; Adrenergic signaling in cardiomyocytes; Prostate cancer 0 High Q8CBR6 Tsukushin OS=Mus musculus OX=10090 GN=Tsku PE=2 SV=2 0 12.018 8 2 4 2 354 38.3 6.61 18965.22852 1 cell organization and biogenesis;regulation of biological process;response to stimulus extracellular;membrane protein binding;receptor activity;signal transducer activity "Pf12799, Pf13855" 244152 ENSMUSG00000049580.12 Tsku 7 0 High A8DIL0 Galectin OS=Mus musculus OX=10090 GN=Lgals8 PE=1 SV=1 0 10.836 14 4 4 4 325 37 8.95 cell differentiation;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane protein binding Pf00337 56048 ENSMUSG00000057554.13 Lgals8 13 0 High P22437 Prostaglandin G/H synthase 1 OS=Mus musculus OX=10090 GN=Ptgs1 PE=1 SV=1 0 10.44 7 3 4 3 602 69 6.83 14629.46191 7247.788574 1 1 cell differentiation;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;endoplasmic reticulum;Golgi;membrane;nucleus antioxidant activity;catalytic activity;metal ion binding;protein binding "Pf00008, Pf03098, Pf07974" 19224 ENSMUSG00000047250.13 Ptgs1 2 Synthesis of Prostaglandins (PG) and Thromboxanes (TX); COX reactions Regulation of lipolysis in adipocytes; Metabolic pathways; Platelet activation; Arachidonic acid metabolism; Serotonergic synapse 0 High A0A171KXD3 Protein arginine N-methyltransferase 1 OS=Mus musculus OX=10090 GN=Prmt1 PE=1 SV=1 0.002 5.226 12 3 4 3 318 36.5 6.19 1704.826782 13118.34082 1 1 cell organization and biogenesis;metabolic process catalytic activity "Pf05175, Pf06325, Pf08241, Pf12847, Pf13489, Pf13649, Pf13847" ENSMUSG00000109324.1 7 0 Medium A2AG06 Meiosis-specific coiled-coil domain-containing protein MEIOC OS=Mus musculus OX=10090 GN=Meioc PE=1 SV=1 0.022 1.64 1 1 4 1 965 108.8 6.89 1 1 2 1 281283.5625 298984.4375 181139.4219 65442.04297 1 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus protein binding Pf15189 268491 ENSMUSG00000051455.13 Gm1564; Meioc 11 0 High Q9D6Z1 Nucleolar protein 56 OS=Mus musculus OX=10090 GN=Nop56 PE=1 SV=2 0 7.252 4 2 4 2 580 64.4 9.14 7561.928223 1 metabolic process cytoplasm;membrane;nucleus protein binding;RNA binding "Pf01798, Pf08060, Pf08156" 67134 ENSMUSG00000027405.16 Nop56 2 Major pathway of rRNA processing in the nucleolus and cytosol Ribosome biogenesis in eukaryotes 0 High Q9CQ69 Cytochrome b-c1 complex subunit 8 OS=Mus musculus OX=10090 GN=Uqcrq PE=1 SV=3 0 5.54 26 2 4 2 82 9.8 10.26 65669.03613 80437.4082 57876.51758 154276.707 2 2 2 2 metabolic process;transport membrane;mitochondrion catalytic activity;transporter activity Pf02939 22272 ENSMUSG00000044894.14 Uqcrq 11 Respiratory electron transport Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 High Q8BJ64 "Choline dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Chdh PE=1 SV=1" 0 9.875 7 3 4 3 596 66.4 8.51 metabolic process membrane;mitochondrion catalytic activity;nucleotide binding "Pf00732, Pf01266, Pf05199, Pf05834, Pf13450" 218865 ENSMUSG00000015970.18 Chdh 14 Choline catabolism "Metabolic pathways; Glycine, serine and threonine metabolism" 0 High B1AQF4 Dual specificity protein phosphatase OS=Mus musculus OX=10090 GN=Dusp3 PE=1 SV=1 0.002 5.07 14 2 4 2 210 23.2 7.31 metabolic process;regulation of biological process cytosol;nucleus catalytic activity;protein binding "Pf00102, Pf00782" 72349 ENSMUSG00000003518.13 Dusp3 11 0 High Q6GQT9 Nodal modulator 1 OS=Mus musculus OX=10090 GN=Nomo1 PE=1 SV=1 0 5.317 3 2 4 2 1214 133.3 6.09 31413.68652 2 membrane "Pf05738, Pf13620, Pf13715, Pf14686" 211548 ENSMUSG00000030835.6 Nomo1 7 0 High P22725 Protein Wnt-5a OS=Mus musculus OX=10090 GN=Wnt5a PE=1 SV=2 0.002 4.377 7 2 4 2 380 42.3 8.46 cell communication;cell differentiation;cell organization and biogenesis;cell proliferation;cellular component movement;development;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;extracellular;organelle lumen DNA binding;protein binding Pf00110 22418 ENSMUSG00000021994.14 Wnt5a 14 "WNT5A-dependent internalization of FZD4; WNT ligand biogenesis and trafficking; Asymmetric localization of PCP proteins; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Ca2+ pathway; Cargo recognition for clathrin-mediated endocytosis" mTOR signaling pathway; Wnt signaling pathway; Basal cell carcinoma; Hippo signaling pathway; Breast cancer; Signaling pathways regulating pluripotency of stem cells; Melanogenesis; Axon guidance; HTLV-I infection; Proteoglycans in cancer; Pathways in cancer 0 High Q9DCT8 Cysteine-rich protein 2 OS=Mus musculus OX=10090 GN=Crip2 PE=1 SV=1 0 9.063 35 3 4 3 208 22.7 8.63 22976.03027 33483.07422 2 1 regulation of biological process metal ion binding;protein binding Pf00412 68337 ENSMUSG00000006356.10 Crip2 12 0 High Q8BHG3 Cell cycle control protein 50B OS=Mus musculus OX=10090 GN=Tmem30b PE=2 SV=1 0.002 4.449 6 2 4 1 353 39.2 7.36 100636.4063 20531.10156 1 1 regulation of biological process;transport membrane transporter activity Pf03381 238257 ENSMUSG00000034435.5 Tmem30b 12 0 Medium Q3TQQ9 Uncharacterized protein C1orf112 homolog OS=Mus musculus OX=10090 PE=1 SV=2 0.027 1.564 1 1 4 1 903 101.2 6.84 6577.551758 1 Pf14868 381306 ENSMUSG00000041406.14 BC055324 1 0 High Q9DBB8 "Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase OS=Mus musculus OX=10090 GN=Dhdh PE=1 SV=1" 0.002 4.532 7 2 4 2 333 36.3 6.44 48867.30859 33482.17969 9000.707031 9635.493164 1 1 1 1 metabolic process catalytic activity "Pf01408, Pf02894, Pf03807" 71755 ENSMUSG00000011382.8 Dhdh 7 Pentose and glucuronate interconversions; Metabolism of xenobiotics by cytochrome P450 0 High Q8BFW7 Lipoma-preferred partner homolog OS=Mus musculus OX=10090 GN=Lpp PE=1 SV=1 0.002 4.718 4 2 4 2 613 65.8 7.37 11485.72266 6261.744629 1 1 cytoplasm;cytosol;nucleus metal ion binding;protein binding "Pf00412, Pf02318" 210126 ENSMUSG00000033306.14 Lpp 16 0 High Q9D0T1 NHP2-like protein 1 OS=Mus musculus OX=10090 GN=Snu13 PE=1 SV=4 0.003 3.648 16 2 4 2 128 14.2 8.46 cell organization and biogenesis;metabolic process membrane;nucleus;spliceosomal complex protein binding;RNA binding Pf01248 20826; 100862468 ENSMUSG00000063480.7 Nhp2l1; Snu13; LOC100862468 15; 4 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Major pathway of rRNA processing in the nucleolus and cytosol Spliceosome; Ribosome biogenesis in eukaryotes 0 High Q8BQ46 "TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor OS=Mus musculus OX=10090 GN=Taf15 PE=1 SV=1" 0 5.9 6 2 4 1 557 58.6 8.4 1 1 regulation of biological process cytoplasm;nucleus metal ion binding;RNA binding "Pf00076, Pf00641, Pf13893, Pf14259" 70439 ENSMUSG00000020680.15 Taf15 11 Basal transcription factors; Transcriptional misregulation in cancer 0 High Q99KB8 "Hydroxyacylglutathione hydrolase, mitochondrial OS=Mus musculus OX=10090 GN=Hagh PE=1 SV=2" 0 7.868 11 3 4 3 309 34.1 7.75 8338.331055 8849.071289 1 1 metabolic process cytoplasm;mitochondrion;organelle lumen catalytic activity;metal ion binding Pf00753 14651 Hagh 17 Pyruvate metabolism 0 High A0A0B4J1J0 Immunoglobulin kappa variable 4-50 (Fragment) OS=Mus musculus OX=10090 GN=Igkv4-50 PE=4 SV=1 0 7.32 26 2 4 2 117 12.8 5.19 2 4 903931.9688 103821.0703 2 1 response to stimulus "Pf00047, Pf07679, Pf07686" 381782 ENSMUSG00000076562.1 Igkv4-50 6 0 High Q01768 Nucleoside diphosphate kinase B OS=Mus musculus OX=10090 GN=Nme2 PE=1 SV=1 0 6.289 20 3 4 3 152 17.4 7.5 98244.19165 58767.42334 80165.04883 69186.70215 3 2 1 2 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding Pf00334 18103 ENSMUSG00000020857.11 Nme2 11 Interconversion of nucleotide di- and triphosphates; Neutrophil degranulation Metabolic pathways; Purine metabolism; Pyrimidine metabolism 0 Medium Q31125 Zinc transporter SLC39A7 OS=Mus musculus OX=10090 GN=Slc39a7 PE=1 SV=2 0.04 1.416 2 1 4 1 476 50.6 6.87 1442.455933 1 cellular homeostasis;transport endoplasmic reticulum;Golgi;membrane protein binding;transporter activity Pf02535 14977 ENSMUSG00000024327.15 Slc39a7 17 Zinc influx into cells by the SLC39 gene family 0 High Q8BU03 Periodic tryptophan protein 2 homolog OS=Mus musculus OX=10090 GN=Pwp2 PE=1 SV=1 0.002 4.388 3 3 4 3 919 102.8 6.23 11068.66895 1 cell organization and biogenesis;metabolic process nucleus protein binding;RNA binding "Pf00400, Pf04003" 110816 ENSMUSG00000032834.11 Pwp2 10 Major pathway of rRNA processing in the nucleolus and cytosol Ribosome biogenesis in eukaryotes 0 High Q9D0I9 "Arginine--tRNA ligase, cytoplasmic OS=Mus musculus OX=10090 GN=Rars1 PE=1 SV=2" 0 7.61 5 3 4 3 660 75.6 7.55 2138.122559 1 metabolic process cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00750, Pf03485, Pf05746" 104458 ENSMUSG00000018848.4 Rars 11 Aminoacyl-tRNA biosynthesis 0 High P33267 Cytochrome P450 2F2 OS=Mus musculus OX=10090 GN=Cyp2f2 PE=1 SV=1 0 6.029 5 2 4 2 491 55.9 7.9 34222.88672 1 metabolic process;response to stimulus endoplasmic reticulum;membrane catalytic activity;metal ion binding Pf00067 13107 ENSMUSG00000052974.8 Cyp2f2 7 Xenobiotics Metabolism of xenobiotics by cytochrome P450 0 High Q6P542 ATP-binding cassette sub-family F member 1 OS=Mus musculus OX=10090 GN=Abcf1 PE=1 SV=1 0 7.997 5 3 4 3 837 94.9 6.51 metabolic process;regulation of biological process cytoplasm;cytosol;membrane;nucleus;ribosome catalytic activity;nucleotide binding;RNA binding;translation regulator activity "Pf00005, Pf13304" 224742 ENSMUSG00000038762.15 Abcf1 17 ABC-family proteins mediated transport 0 High D6REG4 Glyoxylate reductase/hydroxypyruvate reductase OS=Mus musculus OX=10090 GN=Grhpr PE=1 SV=1 0.005 2.92 6 1 4 1 197 21.2 7.8 9527.65918 16749.23633 12530.3291 1 1 1 metabolic process catalytic activity;nucleotide binding "Pf00389, Pf02826" ENSMUSG00000035637.14 4 0 Medium Q9QZZ4 Unconventional myosin-XV OS=Mus musculus OX=10090 GN=Myo15a PE=1 SV=2 0.031 1.508 0 1 4 1 3511 395.4 9.16 54422.46094 105550.1406 66059.67969 93376.22656 1 1 1 1 response to stimulus cytoplasm;cytoskeleton catalytic activity;motor activity;nucleotide binding;protein binding "Pf00063, Pf00373, Pf00784, Pf07653" 17910 ENSMUSG00000042678.16 Myo15 11 0 High P60122 RuvB-like 1 OS=Mus musculus OX=10090 GN=Ruvbl1 PE=1 SV=1 0 5.891 8 3 4 3 456 50.2 6.42 16655.11865 12514.10156 2 1 cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytosol;nucleus catalytic activity;nucleotide binding;protein binding "Pf00004, Pf01078, Pf01695, Pf05496, Pf06068, Pf06414, Pf07726, Pf13191, Pf13238, Pf13245, Pf13481" 56505 ENSMUSG00000030079.15 Ruvbl1 6 DNA Damage Recognition in GG-NER; Ub-specific processing proteases; UCH proteinases; Deposition of new CENPA-containing nucleosomes at the centromere; Formation of the beta-catenin:TCF transactivating complex Wnt signaling pathway 0 High Q9D6Y9 "1,4-alpha-glucan-branching enzyme OS=Mus musculus OX=10090 GN=Gbe1 PE=1 SV=1" 0 7.165 4 2 4 2 702 80.3 6.43 1 1 101830.1719 52074.98828 71147.75684 2 1 2 metabolic process catalytic activity "Pf00128, Pf02806, Pf02922" 74185 ENSMUSG00000022707.16 Gbe1 16 Glycogen synthesis Metabolic pathways; Starch and sucrose metabolism 0 High P97807 "Fumarate hydratase, mitochondrial OS=Mus musculus OX=10090 GN=Fh PE=1 SV=3" 0.002 4.11 6 2 4 2 507 54.3 9.04 1 2 1 1 2 1 409560.4063 209582.8672 192531.2344 73035.56445 2 2 1 2 metabolic process cytoplasm;mitochondrion catalytic activity "Pf00206, Pf10415" 14194 ENSMUSG00000026526.14 Fh1 1 Citric acid cycle (TCA cycle) Pyruvate metabolism; Citrate cycle (TCA cycle); Metabolic pathways; Pathways in cancer; Renal cell carcinoma; Carbon metabolism 0 High Q80VA0 N-acetylgalactosaminyltransferase 7 OS=Mus musculus OX=10090 GN=Galnt7 PE=1 SV=2 0.002 5.141 5 3 3 3 657 75.4 7.93 545539.75 376280.3125 127717.8203 1 1 1 metabolic process Golgi;membrane catalytic activity;metal ion binding "Pf00535, Pf00652, Pf02709, Pf10111" 108150 ENSMUSG00000031608.13 Galnt7 8 O-linked glycosylation of mucins Metabolic pathways; Mucin type O-glycan biosynthesis 0 High Q8K0M3 Sorbs3 protein OS=Mus musculus OX=10090 GN=Sorbs3 PE=1 SV=1 0 8.959 7 3 3 3 680 76.7 9.29 11837.77344 1 Acetyl [N-Term] cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton;nucleus protein binding "Pf00018, Pf02208, Pf07653, Pf14604" 20410 Sorbs3 14 0 High P28654 Decorin OS=Mus musculus OX=10090 GN=Dcn PE=1 SV=1 0.002 4.576 7 2 3 2 354 39.8 8.68 67621.25391 156312.9961 10696.52051 2 2 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;extracellular enzyme regulator activity;protein binding;RNA binding "Pf01462, Pf12799, Pf13306, Pf13855" 13179 ENSMUSG00000019929.16 Dcn 10 A tetrasaccharide linker sequence is required for GAG synthesis; ECM proteoglycans; CS/DS degradation; Degradation of the extracellular matrix; Dermatan sulfate biosynthesis; Chondroitin sulfate biosynthesis Proteoglycans in cancer; TGF-beta signaling pathway 0 High Q8CHQ9 N-acetyltransferase family 8 member 2 OS=Mus musculus OX=10090 GN=Nat8f2 PE=1 SV=1 0 5.883 8 2 3 2 238 26.4 9.58 development;regulation of biological process endoplasmic reticulum;Golgi;membrane catalytic activity "Pf00583, Pf13302, Pf13508, Pf13523, Pf13527, Pf13673, Pf14542" 93673 ENSMUSG00000033634.7 Cml2; Nat8f2 6 0 Medium D6RJM1 E3 ubiquitin-protein ligase TRIM62 OS=Mus musculus OX=10090 GN=Trim62 PE=1 SV=1 0.011 2.141 5 1 3 1 145 16.4 5.78 metal ion binding;protein binding "Pf00097, Pf13639, Pf13923, Pf14835, Pf15227" ENSMUSG00000041000.8 4 0 High A0A0B4J1J4 Immunoglobulin heavy variable V9-2 (Fragment) OS=Mus musculus OX=10090 GN=Ighv9-2 PE=4 SV=1 0.002 4.937 26 2 3 1 117 13.3 8.41 1 1 72392.76563 24694.875 93180.625 66413.875 1 1 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding "Pf00047, Pf07686" ENSMUSG00000094102.1 LOC674146 12 0 Medium A2A432 Cullin-4B OS=Mus musculus OX=10090 GN=Cul4b PE=1 SV=1 0.013 1.947 1 1 3 1 970 110.6 8.37 18711.96484 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytosol;nucleus catalytic activity;DNA binding;protein binding "Pf00888, Pf10557" 72584 ENSMUSG00000031095.15 Cul4b X Dual incision in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; DNA Damage Recognition in GG-NER; Formation of Incision Complex in GG-NER; Neddylation; Formation of TC-NER Pre-Incision Complex; Gap-filling DNA repair synthesis and ligation in TC-NER Ubiquitin mediated proteolysis; Nucleotide excision repair 0 Medium A0A1C7CYV0 Plastin-3 (Fragment) OS=Mus musculus OX=10090 GN=Pls3 PE=1 SV=1 0.02 1.684 2 1 3 1 629 70.6 5.62 13094.9248 14326.21777 1 1 metal ion binding;protein binding "Pf00307, Pf13499" ENSMUSG00000016382.15 X 0 High Q3UFB7 High affinity nerve growth factor receptor OS=Mus musculus OX=10090 GN=Ntrk1 PE=1 SV=2 0.002 4.665 5 3 3 3 799 87.7 6.29 19148.74805 14603.05762 1 1 cell death;cell differentiation;cell organization and biogenesis;cellular component movement;development;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;endosome;membrane catalytic activity;nucleotide binding;protein binding;receptor activity;signal transducer activity "Pf00069, Pf07679, Pf07714" 18211 ENSMUSG00000028072.6 Ntrk1 3 Frs2-mediated activation; Retrograde neurotrophin signalling; TRKA activation by NGF; PI3K/AKT activation; ARMS-mediated activation Endocytosis; MAPK signaling pathway; Transcriptional misregulation in cancer; Neurotrophin signaling pathway; Pathways in cancer; Thyroid cancer; Central carbon metabolism in cancer; Inflammatory mediator regulation of TRP channels; Apoptosis 0 High P63085 Mitogen-activated protein kinase 1 OS=Mus musculus OX=10090 GN=Mapk1 PE=1 SV=3 0.002 4.36 7 2 3 2 358 41.2 6.98 5401.88623 8881.855469 1 1 cell communication;cell death;cell differentiation;cell proliferation;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;endosome;Golgi;membrane;mitochondrion;nucleus catalytic activity;nucleotide binding;protein binding;signal transducer activity "Pf00069, Pf01636, Pf07714" 26413 ENSMUSG00000063358.15 Mapk1 16 "NCAM signaling for neurite out-growth; MAP2K and MAPK activation; Spry regulation of FGF signaling; Signal transduction by L1; FCERI mediated MAPK activation; phospho-PLA2 pathway; Regulation of HSF1-mediated heat shock response; Activated TLR4 signalling; Signaling by GPCR; Neutrophil degranulation; Gastrin-CREB signalling pathway via PKC and MAPK; MAPK1 (ERK2) activation; Recycling pathway of L1; Thrombin signalling through proteinase activated receptors (PARs); RHO GTPases Activate WASPs and WAVEs; Golgi Cisternae Pericentriolar Stack Reorganization; Interleukin-20 family signaling; RSK activation; Regulation of actin dynamics for phagocytic cup formation; Activation of the AP-1 family of transcription factors; Growth hormone receptor signaling; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Oxidative Stress Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); Oncogene Induced Senescence; ERKs are inactivated; Negative feedback regulation of MAPK pathway" Oxytocin signaling pathway; ErbB signaling pathway; FoxO signaling pathway; Acute myeloid leukemia; AGE-RAGE signaling pathway in diabetic complications; mTOR signaling pathway; Cholinergic synapse; Platinum drug resistance; Chagas disease (American trypanosomiasis); T cell receptor signaling pathway; Phospholipase D signaling pathway; Retrograde endocannabinoid signaling; Regulation of actin cytoskeleton; MAPK signaling pathway; Type II diabetes mellitus; Progesterone-mediated oocyte maturation; Ras signaling pathway; Prolactin signaling pathway; TNF signaling pathway; VEGF signaling pathway; Focal adhesion; NOD-like receptor signaling pathway; Insulin signaling pathway; Endometrial cancer; Long-term potentiation; Toxoplasmosis; Chemokine signaling pathway; Breast cancer; Melanoma; Platelet activation; Signaling pathways regulating pluripotency of stem cells; Tuberculosis; Melanogenesis; Hepatitis B; Axon guidance; Oocyte meiosis; Osteoclast differentiation; Non-small cell lung cancer; Adherens junction; Sphingolipid signaling pathway; B cell receptor signaling pathway; Dorso-ventral axis formation; Glutamatergic synapse; Toll-like receptor signaling pathway; Pertussis; Proteoglycans in cancer; Salmonella infection; Fc gamma R-mediated phagocytosis; Thyroid hormone signaling pathway; Neurotrophin signaling pathway; Long-term depression; cGMP-PKG signaling pathway; TGF-beta signaling pathway; Rap1 signaling pathway; HIF-1 signaling pathway; Pathways in cancer; Influenza A; Hepatitis C; Alzheimer's disease; Alcoholism; Pancreatic cancer; Thyroid cancer; PI3K-Akt signaling pathway; cAMP signaling pathway; Vascular smooth muscle contraction; Renal cell carcinoma; GnRH signaling pathway; Natural killer cell mediated cytotoxicity; Prion diseases; Gap junction; Circadian entrainment; Glioma; Fc epsilon RI signaling pathway; EGFR tyrosine kinase inhibitor resistance; Leishmaniasis; Central carbon metabolism in cancer; Choline metabolism in cancer; Estrogen signaling pathway; Th1 and Th2 cell differentiation; Colorectal cancer; Viral carcinogenesis; Chronic myeloid leukemia; Serotonergic synapse; Adrenergic signaling in cardiomyocytes; Prostate cancer; Endocrine resistance; Bladder cancer; Aldosterone-regulated sodium reabsorption; Apoptosis 0 High D3YVC9 Graves disease carrier protein homolog (Fragment) OS=Mus musculus OX=10090 GN=Slc25a16 PE=1 SV=1 0.005 2.956 4 1 3 1 322 34.9 9.95 18052.41992 30824.29297 1 1 transport membrane;mitochondrion Pf00153 ENSMUSG00000071253.8 10 0 High Q8BJU0 Small glutamine-rich tetratricopeptide repeat-containing protein alpha OS=Mus musculus OX=10090 GN=Sgta PE=1 SV=2 0.004 3.396 7 2 3 2 315 34.3 5.06 42055.04688 7211.448242 1 1 metabolic process;regulation of biological process cytoplasm;cytosol;membrane;nucleus protein binding "Pf00515, Pf07719, Pf13181, Pf13414, Pf13424, Pf13431, Pf13432, Pf14559" 52551 ENSMUSG00000004937.6 Sgta 10 0 High Q5SRY7 F-box/WD repeat-containing protein 11 OS=Mus musculus OX=10090 GN=Fbxw11 PE=1 SV=1 0.002 4.779 7 2 3 2 542 62 7.12 106762.2734 68657.05469 13639.04492 1 1 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;nucleus catalytic activity;protein binding "Pf00400, Pf00646, Pf08801, Pf12125, Pf12937" 103583 ENSMUSG00000020271.17 Fbxw11 11 Dectin-1 mediated noncanonical NF-kB signaling; NIK-->noncanonical NF-kB signaling; Activation of NF-kappaB in B cells; Activated TLR4 signalling; Antigen processing: Ubiquitination & Proteasome degradation; FCERI mediated NF-kB activation; Regulation of PLK1 Activity at G2/M Transition; Downstream TCR signaling; Interleukin-1 family signaling; Neddylation; MAP3K8 (TPL2)-dependent MAPK1/3 activation Wnt signaling pathway; Ubiquitin mediated proteolysis; Hippo signaling pathway; Circadian rhythm; Oocyte meiosis; Hedgehog signaling pathway 0 Medium P56546 C-terminal-binding protein 2 OS=Mus musculus OX=10090 GN=Ctbp2 PE=1 SV=2 0.011 2.209 2 1 3 1 445 48.9 6.95 6272.249512 1 cell differentiation;metabolic process;regulation of biological process cytosol;nucleus catalytic activity;nucleotide binding;protein binding "Pf00389, Pf02826" 13017 ENSMUSG00000030970.16 Ctbp2 7 Wnt signaling pathway; Notch signaling pathway; Pathways in cancer; Chronic myeloid leukemia 0 High G3X9M0 "28S ribosomal protein S29, mitochondrial OS=Mus musculus OX=10090 GN=Dap3 PE=1 SV=1" 0.002 4.4 8 2 3 2 396 45.3 9.11 8699.102539 86524.21875 6653.753906 2 1 1 cell death;cell organization and biogenesis mitochondrion;organelle lumen;ribosome RNA binding;structural molecule activity "Pf05673, Pf10236" 65111 ENSMUSG00000068921.14 Dap3 3 0 Medium Q8VFG4 Olfactory receptor OS=Mus musculus OX=10090 GN=Olfr1370 PE=2 SV=1 0.05 1.337 3 1 3 1 316 35.3 8.9 379688.5625 42420.82422 1 1 Met-loss [N-Term] regulation of biological process;response to stimulus membrane receptor activity;signal transducer activity "Pf00001, Pf13853" 258528 ENSMUSG00000042869.2 Olfr1370 13 Olfactory transduction 0 High Q80UY2 E3 ubiquitin-protein ligase KCMF1 OS=Mus musculus OX=10090 GN=Kcmf1 PE=1 SV=1 0.005 3.159 4 1 3 1 381 41.8 5.76 26288.10352 1 metabolic process catalytic activity;metal ion binding "Pf00569, Pf05605" 74287 ENSMUSG00000055239.10 Kcmf1 6 Neutrophil degranulation 0 High A0A0R3P9C8 "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial OS=Mus musculus OX=10090 GN=Ndufa9 PE=1 SV=1" 0 6.59 16 3 3 3 373 42.1 9.09 36420.30859 30658.38672 1 1 metabolic process membrane;mitochondrion catalytic activity "Pf01073, Pf01370, Pf05368, Pf13460" ENSMUSG00000000399.10 6 0 High I7HJR3 Beta-2-glycoprotein 1 (Fragment) OS=Mus musculus OX=10090 GN=Apoh PE=1 SV=1 0.003 3.691 19 2 3 2 154 16.8 8.62 coagulation;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;extracellular;membrane enzyme regulator activity;protein binding Pf00084 11818 ENSMUSG00000000049.11 Apoh 11 0 High P52196 Thiosulfate sulfurtransferase OS=Mus musculus OX=10090 GN=Tst PE=1 SV=3 0 7.111 10 2 3 2 297 33.4 7.85 28336.04785 5911.126465 3515.198486 2 1 1 cell differentiation;transport membrane;mitochondrion;organelle lumen catalytic activity;RNA binding Pf00581 22117 ENSMUSG00000044986.8 Tst 15 Metabolic pathways; Sulfur relay system; Cysteine and methionine metabolism; Sulfur metabolism 0 High A0A0G2JDE3 Adhesion G protein-coupled receptor L2 OS=Mus musculus OX=10090 GN=Adgrl2 PE=1 SV=1 0.003 3.635 1 1 3 1 1403 157 6.54 regulation of biological process;response to stimulus membrane protein binding;receptor activity;signal transducer activity "Pf00002, Pf01825, Pf02140, Pf02191, Pf02354, Pf02793, Pf12003" 99633 ENSMUSG00000028184.12 Lphn2; Adgrl2 3 0 High A2ATP6 Myelin expression factor 2 OS=Mus musculus OX=10090 GN=Myef2 PE=1 SV=2 0.002 4.295 4 2 3 2 567 61.1 8.75 6472.237305 1 regulation of biological process nucleus DNA binding;RNA binding "Pf00076, Pf11608, Pf13893, Pf14259" 17876 ENSMUSG00000027201.16 Myef2 2 0 High Q9DB91 Mediator of RNA polymerase II transcription subunit 29 OS=Mus musculus OX=10090 GN=Med29 PE=2 SV=1 0.002 4.818 9 1 3 1 199 21 6.29 89923.53906 23515.85352 1 1 metabolic process;regulation of biological process nucleus Pf11568 67224 ENSMUSG00000003444.8 Med29 7 Mus musculus biological processes; Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes 0 High E9PVX6 Proliferation marker protein Ki-67 OS=Mus musculus OX=10090 GN=Mki67 PE=1 SV=1 0 5.588 2 1 3 1 3177 350.7 9.72 31778.7168 1 cell proliferation;metabolic process;regulation of biological process;response to stimulus chromosome;cytoplasm;membrane;nucleus DNA binding;nucleotide binding;protein binding;RNA binding "Pf00498, Pf08065, Pf15276" 17345 ENSMUSG00000031004.8 Mki67 7 0 High A0A2R8VHW2 Ribosomal L1 domain-containing protein 1 (Fragment) OS=Mus musculus OX=10090 GN=Rsl1d1 PE=1 SV=1 0.002 4.113 7 1 3 1 238 26.6 9.86 8384.980469 1 0 High Q921G9 Tight junction protein 3 OS=Mus musculus OX=10090 GN=Tjp3 PE=1 SV=1 0.002 4.85 3 2 3 1 904 99.1 6.76 10031.92188 4516.525879 34811.42578 1 1 1 regulation of biological process cell surface;membrane;nucleus protein binding "Pf00595, Pf00625, Pf07653, Pf13180" 27375 ENSMUSG00000034917.8 Tjp3 10 Tight junction 0 Medium Q64702 Serine/threonine-protein kinase PLK4 OS=Mus musculus OX=10090 GN=Plk4 PE=1 SV=2 0.017 1.842 1 1 3 1 925 103.7 8.32 14210718.19 11836757.72 11366388.81 2262254.688 1 1 1 1 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process chromosome;cytoplasm;cytoskeleton;cytosol;nucleus catalytic activity;nucleotide binding;protein binding "Pf00069, Pf00659, Pf07714" 20873 ENSMUSG00000025758.10 Plk4 3 Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes FoxO signaling pathway 0 High Q6PAC3 DDB1- and CUL4-associated factor 13 OS=Mus musculus OX=10090 GN=Dcaf13 PE=2 SV=2 0 5.724 3 1 3 1 445 51.4 9.32 metabolic process cytosol;nucleus protein binding;RNA binding "Pf00400, Pf04158" 223499 ENSMUSG00000022300.9; ENSMUSG00000106903.1 Dcaf13 15; CHR_MG4261_PATCH Neddylation; Major pathway of rRNA processing in the nucleolus and cytosol 0 High P34884 Macrophage migration inhibitory factor OS=Mus musculus OX=10090 GN=Mif PE=1 SV=2 0 6.696 18 2 3 2 115 12.5 7.34 60465.17383 2 Met-loss [N-Term] cell organization and biogenesis;cell proliferation;defense response;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;cytosol;extracellular;nucleus catalytic activity;protein binding Pf01187 17319 ENSMUSG00000033307.7 Mif 10 Cell surface interactions at the vascular wall; Neutrophil degranulation Phenylalanine metabolism; Tyrosine metabolism 0 High Q9DBR0 A-kinase anchor protein 8 OS=Mus musculus OX=10090 GN=Akap8 PE=1 SV=1 0 6.906 12 3 3 3 687 76.2 5.14 32312.27148 14479.03027 40723.58984 16747.37012 1 1 1 2 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus;transport chromosome;cytoplasm;Golgi;membrane;mitochondrion;nucleus catalytic activity;DNA binding;metal ion binding;protein binding;RNA binding Pf04988 56399 ENSMUSG00000024045.5 Akap8 17 0 High A0A075B5L6 Immunoglobulin kappa variable 4-81 OS=Mus musculus OX=10090 GN=Igkv4-81 PE=4 SV=7 0.006 2.394 19 1 3 1 96 10.2 5.1 1 1 550002 249896.9063 60283.57422 245291.125 1 1 1 1 Pf07686 ENSMUSG00000076539.3 6 0 High O88685 26S proteasome regulatory subunit 6A OS=Mus musculus OX=10090 GN=Psmc3 PE=1 SV=2 0.005 3.018 6 2 3 2 442 49.5 5.19 metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus;proteasome catalytic activity;nucleotide binding;protein binding "Pf00004, Pf01078, Pf05496, Pf07724, Pf07728, Pf13191" 19182 ENSMUSG00000002102.15 Psmc3 2 The role of GTSE1 in G2/M progression after G2 checkpoint; CDT1 association with the CDC6:ORC:origin complex; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Degradation of beta-catenin by the destruction complex; Autodegradation of the E3 ubiquitin ligase COP1; UCH proteinases; MAPK6/MAPK4 signaling; SCF-beta-TrCP mediated degradation of Emi1; CDK-mediated phosphorylation and removal of Cdc6; Separation of Sister Chromatids; SCF(Skp2)-mediated degradation of p27/p21; GLI3 is processed to GLI3R by the proteasome; Ub-specific processing proteases; Regulation of ornithine decarboxylase (ODC); Activation of NF-kappaB in B cells; Degradation of GLI1 by the proteasome; FCERI mediated NF-kB activation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Hedgehog ligand biogenesis; Neutrophil degranulation; Downstream TCR signaling; Autodegradation of Cdh1 by Cdh1:APC/C; Regulation of RAS by GAPs; Interleukin-1 family signaling; Asymmetric localization of PCP proteins; G2/M Checkpoints; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Regulation of PTEN stability and activity; Ubiquitin-dependent degradation of Cyclin D1; NIK-->noncanonical NF-kB signaling; Removal of licensing factors from origins; M/G1 Transition; Interleukin-20 family signaling; Regulation of RUNX2 expression and activity; Cross-presentation of soluble exogenous antigens (endosomes); ABC-family proteins mediated transport; APC/C:Cdc20 mediated degradation of Securin; Regulation of DNA replication; Dectin-1 mediated noncanonical NF-kB signaling; Antigen processing: Ubiquitination & Proteasome degradation; Orc1 removal from chromatin; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of RUNX3 expression and activity; Hedgehog 'on' state; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Degradation of DVL; Degradation of AXIN Proteasome; Epstein-Barr virus infection 0 High Q8BU14 Translocation protein SEC62 OS=Mus musculus OX=10090 GN=Sec62 PE=1 SV=1 0 6.087 5 2 3 2 398 45.6 7.31 2750.224121 1 cell organization and biogenesis;transport endoplasmic reticulum;membrane transporter activity Pf03839 69276 ENSMUSG00000027706.8 Sec62 3 XBP1(S) activates chaperone genes Protein export; Protein processing in endoplasmic reticulum 0 High A0A075B5K5 Immunoglobulin kappa variable 2-112 OS=Mus musculus OX=10090 GN=Igkv2-112 PE=1 SV=1 0 5.542 13 1 3 1 119 13.2 5.4 1 1 2 1 628340.3125 122006.0156 1 1 Pf07679 ENSMUSG00000076518.6 6 0 High P58854 Gamma-tubulin complex component 3 OS=Mus musculus OX=10090 GN=Tubgcp3 PE=1 SV=2 0.002 5.129 3 2 3 2 905 103.4 8.32 16636.08008 33333.44922 1 1 cell organization and biogenesis cytoplasm;cytoskeleton;membrane protein binding;structural molecule activity Pf04130 259279 ENSMUSG00000000759.14 Tubgcp3 8 Recruitment of NuMA to mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes 0 High Q9QUJ7 Long-chain-fatty-acid--CoA ligase 4 OS=Mus musculus OX=10090 GN=Acsl4 PE=1 SV=2 0 5.366 4 2 3 2 711 79 8.28 16669.84668 8774.782959 2 2 cell differentiation;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;membrane;mitochondrion catalytic activity;nucleotide binding Pf00501 50790 ENSMUSG00000031278.12 Acsl4 X Synthesis of very long-chain fatty acyl-CoAs PPAR signaling pathway; Fatty acid metabolism; Metabolic pathways; Fatty acid degradation; Adipocytokine signaling pathway; Fatty acid biosynthesis; Peroxisome 0 High Q9D6Y7 Mitochondrial peptide methionine sulfoxide reductase OS=Mus musculus OX=10090 GN=Msra PE=1 SV=1 0 5.494 16 3 3 3 233 26 8.41 2710.637695 70905.20313 1 1 metabolic process cytoplasm;cytoskeleton;cytosol;membrane;mitochondrion;nucleus catalytic activity Pf01625 110265 ENSMUSG00000054733.9 Msra 14 Protein repair 0 Medium A2AEG2 Oral-facial-digital syndrome 1 protein homolog OS=Mus musculus OX=10090 GN=Ofd1 PE=1 SV=1 0.044 1.372 1 1 3 1 1019 117.6 5.88 968139.2813 739264.4375 734985.9844 928843.9688 1 1 1 1 cell organization and biogenesis;cellular component movement;regulation of biological process cytoplasm;cytoskeleton;membrane;nucleus catalytic activity;protein binding "Pf06785, Pf10459, Pf13166" 237222 ENSMUSG00000040586.8 Ofd1 X Anchoring of the basal body to the plasma membrane; Hedgehog 'on' state; AURKA Activation by TPX2; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Hedgehog 'off' state; Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes 0 High P57716 Nicastrin OS=Mus musculus OX=10090 GN=Ncstn PE=1 SV=3 0 6.217 3 2 3 2 708 78.4 6.09 cell proliferation;metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;Golgi;membrane catalytic activity;protein binding Pf05450 59287 ENSMUSG00000003458.12 Ncstn 1 Signaling by NOTCH3; Signaling by NOTCH; NRIF signals cell death from the nucleus; Neutrophil degranulation; Signalling by NGF; Nuclear signaling by ERBB4; Signaling by NOTCH4; Regulated proteolysis of p75NTR; EPH-ephrin mediated repulsion of cells Notch signaling pathway; Alzheimer's disease 0 High F8VQB6 Unconventional myosin-X OS=Mus musculus OX=10090 GN=Myo10 PE=1 SV=1 0.005 2.924 1 2 3 1 2062 237.2 6.25 25614.94531 31118.32813 1 1 cellular component movement;regulation of biological process;transport cytoplasm;cytoskeleton;cytosol;membrane catalytic activity;motor activity;nucleotide binding;protein binding "Pf00063, Pf00169, Pf00373, Pf00769, Pf00784, Pf00887, Pf12325, Pf15409" 17909 ENSMUSG00000022272.17 Myo10 15 Regulation of actin dynamics for phagocytic cup formation Fc gamma R-mediated phagocytosis 0 High Q9CPP0 Nucleoplasmin-3 OS=Mus musculus OX=10090 GN=Npm3 PE=1 SV=3 0.005 3.074 10 1 3 1 175 19 4.82 Met-loss+Acetyl [N-Term] metabolic process cytoskeleton;cytosol;nucleus protein binding;RNA binding Pf03066 18150 ENSMUSG00000056209.7 Npm3 19 0 High Q91WT9 Cystathionine beta-synthase OS=Mus musculus OX=10090 GN=Cbs PE=1 SV=3 0 7.521 9 3 3 3 561 61.5 6.48 2698.286377 9528.46582 3422.611816 1 1 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;nucleus catalytic activity;metal ion binding;protein binding "Pf00291, Pf00571" 12411 ENSMUSG00000024039.14 Cbs 17 Cysteine formation from homocysteine "Metabolic pathways; Biosynthesis of amino acids; Cysteine and methionine metabolism; Glycine, serine and threonine metabolism" 0 High Q6PGF5 "BMS1 homolog, ribosome assembly protein (Yeast) OS=Mus musculus OX=10090 GN=Bms1 PE=1 SV=1" 0.003 3.615 1 1 3 1 1284 145.3 6.27 metabolic process nucleus catalytic activity;nucleotide binding;RNA binding "Pf04950, Pf08142" 213895 ENSMUSG00000030138.8 Bms1 6 Major pathway of rRNA processing in the nucleolus and cytosol Ribosome biogenesis in eukaryotes 0 High Q9CWY6 RNA-binding protein with multiple-splicing 2 OS=Mus musculus OX=10090 GN=Rbpms2 PE=1 SV=1 0.002 4.289 27 2 3 2 168 18.3 9.29 13111.19092 6682.176758 2 1 Met-loss+Acetyl [N-Term] development;regulation of biological process cytoplasm protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 71973 ENSMUSG00000032387.15 Rbpms2 9 0 High P29595 NEDD8 OS=Mus musculus OX=10090 GN=Nedd8 PE=1 SV=2 0.002 4.401 17 1 3 1 81 9 7.25 6891.526367 4095.427246 1 1 metabolic process;regulation of biological process;response to stimulus nucleus protein binding "Pf00240, Pf11976" 18002 ENSMUSG00000010376.14 Nedd8 14 Iron uptake and transport; Neddylation; UCH proteinases; Cargo recognition for clathrin-mediated endocytosis; TGF-beta receptor signaling activates SMADs 0 High Q8K5B2 Multiple coagulation factor deficiency protein 2 homolog OS=Mus musculus OX=10090 GN=Mcfd2 PE=1 SV=1 0.002 4.859 36 2 3 2 145 16.2 4.72 metabolic process;regulation of biological process;transport endoplasmic reticulum;extracellular;Golgi metal ion binding Pf13499 193813 ENSMUSG00000024150.11 Mcfd2 17 COPII (Coat Protein 2) Mediated Vesicle Transport; Cargo concentration in the ER 0 High P60060 Protein transport protein Sec61 subunit gamma OS=Mus musculus OX=10090 GN=Sec61g PE=3 SV=1 0.002 4.318 18 1 3 1 68 7.7 9.99 1884.36731 1 Acetyl [N-Term] transport endoplasmic reticulum;membrane transporter activity Pf00584 100042561; 20335; 100043027; 102637269; 100043039 ENSMUSG00000078974.10 Gm10177; Sec61g; Gm11575; LOC102637269; Gm4184 9; 11; 1; 10 XBP1(S) activates chaperone genes Phagosome; Protein export; Protein processing in endoplasmic reticulum 0 High Q8BSE0 Regulator of microtubule dynamics protein 2 OS=Mus musculus OX=10090 GN=Rmdn2 PE=1 SV=1 0.002 4.333 7 2 3 2 410 47 7.56 3872.885498 1 cytoplasm;cytoskeleton;cytosol;membrane;mitochondrion protein binding 381110 ENSMUSG00000036368.7 Fam82a1; Rmdn2 17 0 High A0A075B6A7 Immunoglobulin heavy variable 2-6 (Fragment) OS=Mus musculus OX=10090 GN=Ighv2-6 PE=4 SV=1 0 6.411 14 1 3 1 116 12.6 8.48 74250.28125 17568.32813 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000096670.1 LOC674132 12 0 High P61211 ADP-ribosylation factor-like protein 1 OS=Mus musculus OX=10090 GN=Arl1 PE=1 SV=1 0 6.758 22 3 3 3 181 20.4 5.72 325745 145781.4414 79668.52344 205548.5039 2 2 1 3 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;Golgi;membrane catalytic activity;enzyme regulator activity;metal ion binding;nucleotide binding;protein binding;signal transducer activity "Pf00025, Pf00071, Pf00503, Pf01926, Pf04670, Pf08477, Pf09439" 104303 ENSMUSG00000060904.14 Arl1 10 Retrograde transport at the Trans-Golgi-Network 0 High A0A075B5K6 Immunoglobulin kappa variable 2-109 (Fragment) OS=Mus musculus OX=10090 GN=Igkv2-109 PE=4 SV=4 0.002 4.688 11 1 3 1 120 13 7.12 1 1 224932.9063 237710.9219 16614.36523 163039.2031 1 1 1 1 response to stimulus "Pf07679, Pf07686" 628268 ENSMUSG00000105606.1 Igkv2-109 6 0 High Q8R404 MICOS complex subunit MIC13 OS=Mus musculus OX=10090 GN=Micos13 PE=1 SV=1 0.007 2.335 17 1 3 1 119 13.4 8.63 1 1 81694.28906 90332.96094 30120.51367 64643.94922 1 1 1 1 cell organization and biogenesis membrane;mitochondrion 224904 ENSMUSG00000049760.5 2410015M20Rik 17 0 High Q9DBE8 "Alpha-1,3/1,6-mannosyltransferase ALG2 OS=Mus musculus OX=10090 GN=Alg2 PE=1 SV=2" 0 8.4 12 3 3 3 415 47.4 7.97 66752.67969 2303.677246 1 1 metabolic process;response to stimulus cytoplasm;membrane;nucleus catalytic activity;protein binding "Pf00534, Pf13439, Pf13524, Pf13579, Pf13692" 56737 ENSMUSG00000039740.6 Alg2 4 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" Metabolic pathways; N-Glycan biosynthesis 0 High Q8CHT0 "Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Aldh4a1 PE=1 SV=3" 0 8.169 6 3 3 3 562 61.8 8.24 31044.76025 3 cell organization and biogenesis;metabolic process mitochondrion;organelle lumen catalytic activity;protein binding "Pf00171, Pf06810" 212647 ENSMUSG00000028737.15 Aldh4a1 4 Proline catabolism; Glyoxylate metabolism and glycine degradation "Arginine and proline metabolism; Metabolic pathways; Alanine, aspartate and glutamate metabolism" 0 High Q60766 Immunity-related GTPase family M protein 1 OS=Mus musculus OX=10090 GN=Irgm1 PE=1 SV=1 0 8.489 16 3 3 3 409 46.5 8.28 30545.44922 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;endosome;Golgi;membrane;vacuole catalytic activity;nucleotide binding "Pf01926, Pf05049" 15944 ENSMUSG00000046879.7 Irgm1 11 Toxoplasmosis 0 High A0A0R4J0V5 DNA-directed RNA polymerase subunit OS=Mus musculus OX=10090 GN=Polr2a PE=1 SV=1 0.002 4.291 3 2 3 2 1932 213.3 7.43 113608.125 314066.9375 77123.21094 256567.6484 1 2 1 2 metabolic process;regulation of biological process cytoplasm;nucleus catalytic activity;DNA binding;metal ion binding;protein binding;RNA binding "Pf00623, Pf04983, Pf04990, Pf04992, Pf04997, Pf04998, Pf05000" 20020 ENSMUSG00000005198.15 Polr2a 11 0 High A0A0B4J1E6 "Fc receptor, IgG, low affinity IIb OS=Mus musculus OX=10090 GN=Fcgr2b PE=1 SV=1" 0 6.176 8 2 3 2 340 37.8 6.73 cell organization and biogenesis;defense response;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;cytoskeleton;endosome;extracellular;membrane protein binding;receptor activity;signal transducer activity "Pf00047, Pf07679, Pf13895, Pf13927" 14130 ENSMUSG00000026656.15 Fcgr2b 1 Role of phospholipids in phagocytosis; Neutrophil degranulation; Regulation of actin dynamics for phagocytic cup formation; FCGR activation 0 High P56656 Cytochrome P450 2C39 OS=Mus musculus OX=10090 GN=Cyp2c39 PE=1 SV=2 0.002 4.728 6 2 3 1 490 55.8 7.93 metabolic process endoplasmic reticulum;membrane catalytic activity;metal ion binding Pf00067 13098 ENSMUSG00000025003.6 Cyp2c39 19 Steroid hormone biosynthesis; Retinol metabolism; Metabolic pathways; Linoleic acid metabolism; Arachidonic acid metabolism; Chemical carcinogenesis; Serotonergic synapse; Inflammatory mediator regulation of TRP channels 0 High Q9D024 Coiled-coil domain-containing protein 47 OS=Mus musculus OX=10090 GN=Ccdc47 PE=1 SV=2 0 6.322 8 2 3 2 483 55.8 4.84 87112.3125 321041.375 8941.399414 102915.2148 1 1 1 2 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;membrane metal ion binding;RNA binding Pf07946 67163 ENSMUSG00000078622.8 Ccdc47 11 0 High A2ABV5 Mediator of RNA polymerase II transcription subunit 14 OS=Mus musculus OX=10090 GN=Med14 PE=1 SV=1 0 5.621 2 2 3 2 1459 160.9 8.53 32037.98804 11634.20215 2 1 metabolic process;regulation of biological process;response to stimulus membrane;nucleus receptor activity "Pf08638, Pf15449" 26896 ENSMUSG00000064127.13 Med14 X Generic Transcription Pathway; Mus musculus biological processes; Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes Thyroid hormone signaling pathway 0 High D3Z5J3 Sorbin and SH3 domain-containing protein 1 OS=Mus musculus OX=10090 GN=Sorbs1 PE=1 SV=1 0.005 2.899 3 2 3 2 938 103.9 5.94 6405.919922 1 cell organization and biogenesis;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;membrane;nucleus protein binding "Pf00018, Pf02208, Pf07267, Pf07653, Pf14604" 20411 ENSMUSG00000025006.15 Sorbs1 19 Smooth Muscle Contraction 0 High F8WJ05 Inter-alpha-trypsin inhibitor heavy chain H1 OS=Mus musculus OX=10090 GN=Itih1 PE=1 SV=1 0 7.159 5 3 3 3 911 101.6 6.96 4146.592773 38818.24219 1 1 metabolic process;regulation of biological process extracellular enzyme regulator activity "Pf00092, Pf06668, Pf08487, Pf13519, Pf13768" 16424 ENSMUSG00000006529.14 Itih1 14 0 High Q3V1T4 Prolyl 3-hydroxylase 1 OS=Mus musculus OX=10090 GN=P3h1 PE=1 SV=2 0.002 4.554 7 3 3 3 739 83.6 5.14 47176.94531 61297.35156 27593.95117 1 1 1 cell growth;cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;endoplasmic reticulum;extracellular;membrane;nucleus catalytic activity;metal ion binding;protein binding Pf13640 56401 ENSMUSG00000028641.16 Lepre1; P3h1 4 Collagen biosynthesis and modifying enzymes 0 High P08249 "Malate dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Mdh2 PE=1 SV=3" 0.002 4.104 5 1 3 1 338 35.6 8.68 1 1 20910.79883 184185.8906 29088.3457 1 1 1 metabolic process membrane;mitochondrion;nucleus;organelle lumen catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00056, Pf01073, Pf01118, Pf02866, Pf13460" 17448 ENSMUSG00000019179.10 Mdh2 5 Gluconeogenesis; Citric acid cycle (TCA cycle) Pyruvate metabolism; Citrate cycle (TCA cycle); Metabolic pathways; Cysteine and methionine metabolism; Carbon metabolism; Glyoxylate and dicarboxylate metabolism 0 High A0A0R4J1Z3 Transmembrane protein 33 OS=Mus musculus OX=10090 GN=Tmem33 PE=1 SV=1 0.003 3.346 7 2 3 2 246 27.9 9.66 3482.557861 1 cell organization and biogenesis;regulation of biological process;response to stimulus endoplasmic reticulum;membrane;nucleus protein binding;structural molecule activity Pf03661 67878 ENSMUSG00000037720.16 Tmem33 5 0 High Q71RI9 Kynurenine--oxoglutarate transaminase 3 OS=Mus musculus OX=10090 GN=Kyat3 PE=1 SV=1 0.005 2.907 6 2 3 2 455 51.1 8.37 4128.641602 1 metabolic process mitochondrion catalytic activity;protein binding;RNA binding "Pf00155, Pf01041, Pf01053" 229905 ENSMUSG00000040213.13 Ccbl2; Kyat3 3 Tryptophan metabolism; Metabolic pathways; Selenocompound metabolism; Chemical carcinogenesis 0 High Q91VS8 "FERM, ARHGEF and pleckstrin domain-containing protein 2 OS=Mus musculus OX=10090 GN=Farp2 PE=1 SV=2" 0 5.985 2 2 3 2 1065 121.2 8.44 2217.503662 11505.88965 6798.516113 1 1 1 cell differentiation;cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol protein binding "Pf00169, Pf00373, Pf00621, Pf08736, Pf09379, Pf09380" 227377 ENSMUSG00000034066.13 Farp2 1 SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Adherens junction; Rap1 signaling pathway 0 High P10810 Monocyte differentiation antigen CD14 OS=Mus musculus OX=10090 GN=Cd14 PE=1 SV=1 0.002 5.259 9 2 3 2 366 39.2 5.21 28903.38477 18916.08594 4435.400391 1 1 1 defense response;regulation of biological process;response to stimulus;transport cell surface;extracellular;Golgi;membrane protein binding 12475 ENSMUSG00000051439.6 Cd14 18 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon; Ligand-dependent caspase activation; Activated TLR4 signalling; Regulation of TLR by endogenous ligand; Neutrophil degranulation; IKK complex recruitment mediated by RIP1; Transfer of LPS from LBP carrier to CD14; TRAF6-mediated induction of TAK1 complex within TLR4 complex; TRIF-mediated programmed cell death Regulation of actin cytoskeleton; MAPK signaling pathway; Tuberculosis; Phagosome; Toll-like receptor signaling pathway; Transcriptional misregulation in cancer; Pertussis; Salmonella infection; Legionellosis; NF-kappa B signaling pathway; Hematopoietic cell lineage; Amoebiasis 0 High Q8K0L9 Zinc finger and BTB domain-containing protein 20 OS=Mus musculus OX=10090 GN=Zbtb20 PE=1 SV=1 0 7.92 4 2 3 2 741 81 6.55 34163.23877 183618.8438 31627.74414 32204.76367 2 1 1 1 metabolic process;regulation of biological process nucleus DNA binding;metal ion binding;protein binding "Pf00096, Pf00651, Pf13465" 56490 ENSMUSG00000022708.16 Zbtb20 16 0 High Q9ERU9 E3 SUMO-protein ligase RanBP2 OS=Mus musculus OX=10090 GN=Ranbp2 PE=1 SV=2 0 9.263 1 3 3 3 3053 340.9 6.18 9309.385742 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport membrane;mitochondrion;nucleus catalytic activity;enzyme regulator activity;metal ion binding;protein binding;RNA binding "Pf00160, Pf00515, Pf00638, Pf00641, Pf07719, Pf12185, Pf13414, Pf13432" 19386 ENSMUSG00000003226.7 Ranbp2 10 Transcriptional regulation by small RNAs; SUMOylation of RNA binding proteins; snRNP Assembly; SUMOylation of chromatin organization proteins; Resolution of Sister Chromatid Cohesion; Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal; Separation of Sister Chromatids; RHO GTPases Activate Formins; Nuclear Pore Complex (NPC) Disassembly; Regulation of Glucokinase by Glucokinase Regulatory Protein; Transport of Mature mRNA derived from an Intron-Containing Transcript; SUMOylation of DNA damage response and repair proteins; SUMOylation of DNA replication proteins RNA transport 0 High D3YTT4 "Isobutyryl-CoA dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Acad8 PE=1 SV=1" 0.002 4.434 3 1 3 1 413 45 8.02 59178.08594 95341.71875 36690.39844 1 1 1 metabolic process catalytic activity;nucleotide binding "Pf00441, Pf02770, Pf02771, Pf08028" ENSMUSG00000031969.16 9 Branched-chain amino acid catabolism 0 High Q9Z247 Peptidyl-prolyl cis-trans isomerase FKBP9 OS=Mus musculus OX=10090 GN=Fkbp9 PE=1 SV=1 0.004 2.695 3 2 3 2 570 63 5.21 13700.08203 1 metabolic process endoplasmic reticulum;organelle lumen catalytic activity;metal ion binding "Pf00254, Pf13499" 27055 ENSMUSG00000029781.7 Fkbp9 6 0 High Q9DBD0 Inhibitor of carbonic anhydrase OS=Mus musculus OX=10090 GN=Ica PE=1 SV=1 0.004 2.597 2 1 3 1 700 76.7 7.25 regulation of biological process extracellular enzyme regulator activity;metal ion binding Pf00405 71775 ENSMUSG00000033688.10 1300017J02Rik 9 Mineral absorption; HIF-1 signaling pathway 0 High A0A1D5RLI1 "Cytochrome P450, family 2, subfamily c, polypeptide 23 OS=Mus musculus OX=10090 GN=Cyp2c23 PE=1 SV=1" 0 5.312 10 3 3 3 456 52.1 8.13 54142.55371 72622.87256 2 2 metabolic process catalytic activity;metal ion binding Pf00067 226143 ENSMUSG00000025197.9 Cyp2c44; Cyp2c23 19 0 High B0V2N8 Annexin (Fragment) OS=Mus musculus OX=10090 GN=Anxa2 PE=1 SV=1 0.002 3.913 11 2 3 2 176 19.6 5.96 65744.53906 25247.00586 1 1 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;cytosol;endosome;extracellular;membrane;nucleus enzyme regulator activity;metal ion binding;protein binding;RNA binding Pf00191 12306 ENSMUSG00000032231.14 Anxa2 9 0 High Q61554 Fibrillin-1 OS=Mus musculus OX=10090 GN=Fbn1 PE=1 SV=2 0.003 3.704 1 2 3 2 2873 312.1 4.92 1 1 200427.5 53167.7207 22207.94287 2 2 2 metabolic process;regulation of biological process;response to stimulus cell surface;extracellular;membrane metal ion binding;protein binding;structural molecule activity "Pf00683, Pf06247, Pf07645, Pf12662, Pf12947, Pf14670" 14118 ENSMUSG00000027204.13 Fbn1 2 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Molecules associated with elastic fibres; Degradation of the extracellular matrix; Post-translational protein phosphorylation; Integrin cell surface interactions 0 High Q5HZI1 Microtubule-associated tumor suppressor 1 homolog OS=Mus musculus OX=10090 GN=Mtus1 PE=1 SV=2 0 6.703 3 3 3 3 1210 134.3 6.86 18817.47656 6515.252441 1 1 cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;Golgi;membrane;mitochondrion;nucleus catalytic activity;motor activity;protein binding;structural molecule activity "Pf00038, Pf01486, Pf01576, Pf02463, Pf03357, Pf03961, Pf04111, Pf04849, Pf05010, Pf05483, Pf05557, Pf05622, Pf06160, Pf06818, Pf07888, Pf08317, Pf09726, Pf09728, Pf09731, Pf09755, Pf10174, Pf12128, Pf12474, Pf12718, Pf13094, Pf13166, Pf13514, Pf13851, Pf14915, Pf15294" 102103 Mtus1 8 0 Medium Q3TKR3 "NACHT, LRR and PYD domains-containing protein 4C OS=Mus musculus OX=10090 GN=Nlrp4c PE=2 SV=1" 0.014 1.887 1 1 3 1 982 112.6 6.92 7056.97168 1700.991455 1 1 defense response;response to stimulus nucleotide binding;protein binding "Pf02758, Pf05729" 83564 ENSMUSG00000034690.13 Nlrp4c 7 IRF3-mediated induction of type I IFN; Regulation of innate immune responses to cytosolic DNA 0 High Q9DCL9 Multifunctional protein ADE2 OS=Mus musculus OX=10090 GN=Paics PE=1 SV=4 0 6.017 4 1 3 1 425 47 7.23 5856.18457 21762.17188 1 1 metabolic process cytoplasm;membrane catalytic activity;nucleotide binding;protein binding "Pf00731, Pf01259" 67054 ENSMUSG00000029247.17 Paics 5 Purine ribonucleoside monophosphate biosynthesis Metabolic pathways; Purine metabolism 0 High A0A494B9S9 "Splicing factor 3b, subunit 2 (Fragment) OS=Mus musculus OX=10090 GN=Sf3b2 PE=1 SV=1" 0.002 3.821 9 2 3 2 308 33.1 5.08 14399.45605 27811.75977 8456.019531 1 1 1 0 High P06684 Complement C5 OS=Mus musculus OX=10090 GN=C5 PE=1 SV=2 0.002 5.243 3 3 3 3 1680 188.8 6.81 12220.61523 6629.775391 1 1 defense response;metabolic process;regulation of biological process;response to stimulus extracellular enzyme regulator activity;protein binding "Pf00207, Pf01759, Pf01821, Pf01835, Pf07677, Pf07678, Pf07703, Pf11974" 15139 ENSMUSG00000026874.10 Hc 2 Regulation of Complement cascade; Peptide ligand-binding receptors; G alpha (i) signalling events; Activation of C3 and C5; Terminal pathway of complement Herpes simplex infection; Staphylococcus aureus infection; Complement and coagulation cascades; Pertussis; Prion diseases; Systemic lupus erythematosus 0 High A0A0J9YU92 F-box only protein 21 (Fragment) OS=Mus musculus OX=10090 GN=Fbxo21 PE=1 SV=1 0.003 3.646 5 1 3 1 504 59.1 6.23 54771.62891 29381.95898 1 1 DNA binding;protein binding "Pf08755, Pf13369" ENSMUSG00000032898.9 5 0 High Q6ZWX6 Eukaryotic translation initiation factor 2 subunit 1 OS=Mus musculus OX=10090 GN=Eif2s1 PE=1 SV=3 0.005 3.116 6 2 3 2 315 36.1 5.08 cell communication;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus;ribosome protein binding;RNA binding "Pf00575, Pf07541" 13665 ENSMUSG00000021116.10 Eif2s1 12 "L13a-mediated translational silencing of Ceruloplasmin expression; PERK regulates gene expression; Recycling of eIF2:GDP; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ABC-family proteins mediated transport; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Herpes simplex infection; Non-alcoholic fatty liver disease (NAFLD); Influenza A; Hepatitis C; RNA transport; Protein processing in endoplasmic reticulum; Measles; Apoptosis 0 High Q9EQ61 Pescadillo homolog OS=Mus musculus OX=10090 GN=Pes1 PE=1 SV=1 0 6.013 4 2 3 2 584 67.8 6.84 3503.904785 1 cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process chromosome;cytosol;membrane;nucleus protein binding;RNA binding "Pf00533, Pf06732" 64934 ENSMUSG00000020430.12 Pes1 11 Major pathway of rRNA processing in the nucleolus and cytosol 0 High Q64514 Tripeptidyl-peptidase 2 OS=Mus musculus OX=10090 GN=Tpp2 PE=1 SV=3 0.004 3.419 2 2 3 2 1262 139.8 6.58 8935.569336 2 metabolic process cytoplasm;cytosol;nucleus catalytic activity;protein binding "Pf00082, Pf12580, Pf13739" 22019 ENSMUSG00000041763.14 Tpp2 1 Antigen processing: Ubiquitination & Proteasome degradation 0 High Q91WS0 CDGSH iron-sulfur domain-containing protein 1 OS=Mus musculus OX=10090 GN=Cisd1 PE=1 SV=1 0.005 3.245 14 1 3 1 108 12.1 9.06 1 1 regulation of biological process membrane;mitochondrion metal ion binding;protein binding Pf09360 52637 ENSMUSG00000037710.8 Cisd1 10 0 High A0A075B5T5 Immunoglobulin heavy variable V1-5 OS=Mus musculus OX=10090 GN=Ighv1-5 PE=4 SV=1 0 8.578 19 1 3 1 98 10.8 9.07 1 1 285137.0313 1 ENSMUSG00000096499.2 LOC671380 12 0 High E9QAH1 "Golgi autoantigen, golgin subfamily b, macrogolgin 1 OS=Mus musculus OX=10090 GN=Golgb1 PE=1 SV=1" 0.002 4.441 1 2 3 2 3197 365.1 5.06 12294.38086 1 metabolic process Golgi;membrane RNA binding "Pf04111, Pf05622, Pf07888, Pf09726, Pf12128, Pf13166" 224139 ENSMUSG00000034243.16 Golgb1 16 COPI-mediated anterograde transport; Golgi Associated Vesicle Biogenesis 0 High Q922W5 "Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Mus musculus OX=10090 GN=Pycr1 PE=1 SV=1" 0 6.631 8 2 3 2 309 32.4 6.86 10701.36816 10255.58008 15793.19824 1 1 1 metabolic process;regulation of biological process;response to stimulus mitochondrion catalytic activity;nucleotide binding;protein binding "Pf01210, Pf03807, Pf14748" 209027 ENSMUSG00000025140.15 Pycr1 11 Amino acid synthesis and interconversion (transamination) Arginine and proline metabolism; Metabolic pathways; Biosynthesis of amino acids 0 Medium A0A0A6YWB0 Muscleblind-like protein 1 OS=Mus musculus OX=10090 GN=Mbnl1 PE=1 SV=1 0.013 1.976 3 1 3 1 347 37.8 8.75 23576.17578 6631.238281 1 1 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;cytosol;nucleus metal ion binding;RNA binding 56758 ENSMUSG00000027763.13 Mbnl1 3 0 High Q9EQ06 Estradiol 17-beta-dehydrogenase 11 OS=Mus musculus OX=10090 GN=Hsd17b11 PE=1 SV=1 0 6.078 11 3 3 1 298 32.9 8.66 metabolic process cytoplasm;extracellular catalytic activity "Pf00106, Pf08659, Pf13561" 114664 ENSMUSG00000029311.16 Hsd17b11 5 Estrogen biosynthesis 0 High Q9Z1T1 AP-3 complex subunit beta-1 OS=Mus musculus OX=10090 GN=Ap3b1 PE=1 SV=2 0 12.805 4 3 3 3 1105 122.7 5.66 23984.80859 6615.983398 1 1 cell organization and biogenesis;cellular component movement;coagulation;regulation of biological process;transport Golgi;membrane protein binding "Pf01602, Pf13646, Pf14796" 11774 ENSMUSG00000021686.4 Ap3b1 13 Golgi Associated Vesicle Biogenesis Lysosome 0 High Q8BLF1 Neutral cholesterol ester hydrolase 1 OS=Mus musculus OX=10090 GN=Nceh1 PE=1 SV=1 0 6.204 12 3 3 3 408 45.7 7.05 10015.7373 1 metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;membrane catalytic activity "Pf00135, Pf07859" 320024 ENSMUSG00000027698.14 Nceh1 3 LDL clearance Bile secretion 0 High P21614 Vitamin D-binding protein OS=Mus musculus OX=10090 GN=Gc PE=1 SV=2 0 8.048 9 2 3 2 476 53.6 5.5 13615.92188 1 metabolic process;transport cytosol;extracellular protein binding;transporter activity "Pf00273, Pf09164" 14473 ENSMUSG00000035540.12 Gc 5 Vitamin D (calciferol) metabolism 0 High A0A494B9H1 Nucleotide exchange factor SIL1 OS=Mus musculus OX=10090 GN=Sil1 PE=1 SV=1 0.002 3.838 9 2 3 2 417 46.8 6 59460.66406 116090.4844 1 2 0 High A0A1B0GR08 Gamma-tubulin complex component (Fragment) OS=Mus musculus OX=10090 GN=Tubgcp2 PE=1 SV=1 0 5.702 2 1 3 1 900 102.7 6.77 77224.5 244503.125 39077.67578 306605.4688 1 1 1 1 cell organization and biogenesis cytoplasm;cytoskeleton protein binding Pf04130 ENSMUSG00000025474.9 7 0 High P01674 Ig kappa chain V-III region PC 2154 OS=Mus musculus OX=10090 PE=1 SV=1 0 6.525 51 3 3 3 108 11.7 6.27 1 1 837355.3125 307123.3555 162874.0703 70448.23633 2 2 2 2 "Pf00047, Pf07679, Pf07686" 0 High Q3U9G9 Delta(14)-sterol reductase LBR OS=Mus musculus OX=10090 GN=Lbr PE=1 SV=2 0 8.57 7 3 3 3 626 71.4 9.36 31794.86914 15453.42969 21873.13281 1 1 1 metabolic process cytoplasm;membrane;nucleus catalytic activity;DNA binding;protein binding;RNA binding "Pf01222, Pf09465" 98386 ENSMUSG00000004880.11 Lbr 1 Cholesterol biosynthesis 0 High Q61316 Heat shock 70 kDa protein 4 OS=Mus musculus OX=10090 GN=Hspa4 PE=1 SV=1 0 7.565 5 3 3 2 841 94.1 5.24 17555.76172 5839.312012 1 1 cell organization and biogenesis;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;nucleus nucleotide binding;protein binding "Pf00012, Pf06723" 15525 Hspa4 11 0 High P97384 Annexin A11 OS=Mus musculus OX=10090 GN=Anxa11 PE=1 SV=2 0 6.437 5 2 3 2 503 54 7.66 7745.087891 1 cell division;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;membrane;nucleus;vacuole metal ion binding;protein binding;RNA binding Pf00191 11744 ENSMUSG00000021866.15 Anxa11 14 0 High E9PUP1 "Synapse defective 1, Rho GTPase, homolog 2 (C. elegans) OS=Mus musculus OX=10090 GN=Syde2 PE=1 SV=2" 0.003 3.662 2 2 3 2 1314 144.5 8.66 1593284.625 66192.53906 278616.3789 32933.23047 1 1 2 1 regulation of biological process;response to stimulus cytoplasm Pf00620 214804 ENSMUSG00000036863.12 Syde2 3 Rho GTPase cycle 0 High Q64516 Glycerol kinase OS=Mus musculus OX=10090 GN=Gk PE=1 SV=2 0.003 3.566 4 2 3 2 559 61.2 5.87 4531.668945 10144.9707 1 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;nucleotide binding;protein binding "Pf00370, Pf02782" 14933 ENSMUSG00000025059.16 Gyk; Gk X Triglyceride biosynthesis PPAR signaling pathway; Metabolic pathways; Glycerolipid metabolism 0 High Q9R0P3 S-formylglutathione hydrolase OS=Mus musculus OX=10090 GN=Esd PE=1 SV=1 0 6.151 16 3 3 3 282 31.3 7.12 18156.59912 18827.94849 2860.859375 2 2 1 metabolic process cytoplasm catalytic activity;protein binding "Pf00326, Pf00756, Pf05448, Pf12695, Pf12697" 13885 ENSMUSG00000021996.16 Esd 14 Glutathione conjugation Carbon metabolism 0 Medium A0A0R4J1I6 Nuclear pore membrane glycoprotein 210 OS=Mus musculus OX=10090 GN=Nup210 PE=1 SV=1 0.025 1.592 1 1 3 1 1842 199.4 6.6 7121.276855 1 transport endoplasmic reticulum;membrane;nucleus protein binding 54563 ENSMUSG00000030091.17 Nup210 6 0 High O35465 Peptidyl-prolyl cis-trans isomerase FKBP8 OS=Mus musculus OX=10090 GN=Fkbp8 PE=1 SV=2 0 7.013 8 2 3 2 402 43.5 5.16 13069.44238 1 cell death;metabolic process;regulation of biological process;response to stimulus cytosol;endoplasmic reticulum;membrane;mitochondrion catalytic activity;protein binding "Pf00254, Pf00515, Pf07719, Pf13181, Pf13414, Pf13424, Pf13431, Pf13432, Pf14559" 14232 ENSMUSG00000019428.16 Fkbp8 8 0 Medium E9Q616 AHNAK nucleoprotein (desmoyokin) OS=Mus musculus OX=10090 GN=Ahnak PE=1 SV=1 0.016 1.864 2 1 3 1 5656 603.9 6.3 1 1 61408.75391 299814.2813 21506.68555 48061.19141 1 1 1 1 cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton;cytosol;membrane;nucleus protein binding;RNA binding;structural molecule activity 66395 ENSMUSG00000069833.12 Ahnak 19 0 High O08914 Fatty-acid amide hydrolase 1 OS=Mus musculus OX=10090 GN=Faah PE=1 SV=1 0.002 4.448 7 2 3 2 579 63.2 7.87 45034.36719 8956.59375 1 1 metabolic process endoplasmic reticulum;Golgi;membrane catalytic activity;protein binding Pf01425 14073 ENSMUSG00000034171.13 Faah 4 Arachidonic acid metabolism Retrograde endocannabinoid signaling 0 High Q9CQI9 Mediator of RNA polymerase II transcription subunit 30 OS=Mus musculus OX=10090 GN=Med30 PE=1 SV=1 0.002 4.308 7 1 3 1 178 20.3 8.28 9443.463867 45086.85547 13517.63379 28197.5625 1 1 1 1 metabolic process;regulation of biological process;response to stimulus nucleus catalytic activity;protein binding;receptor activity Pf11315 69790 ENSMUSG00000038622.7 Med30 15 Generic Transcription Pathway; Mus musculus biological processes; Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes Thyroid hormone signaling pathway 0 High E9Q9E1 Eukaryotic translation initiation factor 4 gamma 1 OS=Mus musculus OX=10090 GN=Eif4g1 PE=1 SV=1 0.002 4.171 2 2 3 2 1593 175.2 5.38 29553.73828 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus nucleotide binding;protein binding;RNA binding "Pf00566, Pf02020, Pf02847, Pf02854" 208643 ENSMUSG00000045983.15 Eif4g1 16 0 High P42669 Transcriptional activator protein Pur-alpha OS=Mus musculus OX=10090 GN=Pura PE=1 SV=1 0 6.258 18 3 3 2 321 34.9 6.44 190995.7676 108451.8828 75333.96094 146773.584 3 2 2 2 cell death;cell differentiation;cell proliferation;metabolic process;regulation of biological process cytoplasm;nucleus DNA binding;protein binding;RNA binding;translation regulator activity Pf04845 19290 ENSMUSG00000043991.4 Pura 18 1 High P54818 Galactocerebrosidase OS=Mus musculus OX=10090 GN=Galc PE=1 SV=2 0.005 3.177 2 1 3 1 684 77.2 6.74 29175.74023 127828.6484 10258.46875 1 1 1 metabolic process mitochondrion;vacuole catalytic activity Pf02057 14420 ENSMUSG00000021003.9 Galc 12 Glycosphingolipid metabolism Metabolic pathways; Lysosome; Sphingolipid metabolism 0 High Q9CQC9 GTP-binding protein SAR1b OS=Mus musculus OX=10090 GN=Sar1b PE=1 SV=1 0.005 3.248 12 2 3 2 198 22.4 6.11 4933.793457 1 regulation of biological process;response to stimulus;transport endoplasmic reticulum;Golgi;membrane catalytic activity;metal ion binding;nucleotide binding;protein binding;signal transducer activity "Pf00025, Pf00503, Pf01926, Pf08477, Pf09439" 66397 ENSMUSG00000020386.5 Sar1b 11 "Cargo concentration in the ER; Chylomicron assembly; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; COPII (Coat Protein 2) Mediated Vesicle Transport; MHC class II antigen presentation" Legionellosis; Protein processing in endoplasmic reticulum 0 High E9Q8F0 RNA-binding protein 39 OS=Mus musculus OX=10090 GN=Rbm39 PE=1 SV=1 0 6.064 7 2 3 2 415 47 10.52 7712.583984 3900.981445 1 1 metabolic process nucleus RNA binding "Pf00076, Pf13893, Pf14259, Pf15519" ENSMUSG00000027620.16 2 0 Medium A0A140T8N4 Immunoglobulin kappa variable 5-37 (Fragment) OS=Mus musculus OX=10090 GN=Igkv5-37 PE=4 SV=2 0.018 1.818 10 1 3 1 115 12.6 8 1 2 181350.8281 19503.80859 1 1 "Pf00047, Pf07679, Pf07686" 384417 ENSMUSG00000076571.2 Igkv5-37 6 0 High F8WHM5 Golgi apparatus protein 1 (Fragment) OS=Mus musculus OX=10090 GN=Glg1 PE=1 SV=1 0 7.954 2 2 3 2 1163 132.3 6.93 17047.9375 28908.7793 4550.481445 1 1 1 regulation of biological process Golgi;membrane protein binding Pf00839 ENSMUSG00000003316.14 8 0 High Q5SUF2 Luc7-like protein 3 OS=Mus musculus OX=10090 GN=Luc7l3 PE=1 SV=1 0.004 3.472 3 1 3 1 432 51.4 9.77 5933.895996 63959.95313 1 1 cell organization and biogenesis;metabolic process nucleus;spliceosomal complex DNA binding;RNA binding Pf03194 67684 ENSMUSG00000020863.15 Luc7l3 11 0 Medium Q6P6J0 tRNA-specific adenosine deaminase 2 OS=Mus musculus OX=10090 GN=Adat2 PE=1 SV=1 0.032 1.48 4 1 3 1 191 21.3 5.88 191968.3008 707535.125 843115.1719 682169.0313 1 1 1 1 metabolic process catalytic activity;metal ion binding "Pf00383, Pf14439" 66757 ENSMUSG00000019808.8 Adat2 10 0 High Q78XF5 Oligosaccharyltransferase complex subunit OSTC OS=Mus musculus OX=10090 GN=Ostc PE=1 SV=1 0.003 3.711 8 1 3 1 149 16.8 9.13 metabolic process endoplasmic reticulum;membrane Pf04756 66357 ENSMUSG00000041084.8 Ostc 3 0 High Q9QYJ0 DnaJ homolog subfamily A member 2 OS=Mus musculus OX=10090 GN=Dnaja2 PE=1 SV=1 0 8.735 5 2 3 2 412 45.7 6.48 metabolic process;regulation of biological process;response to stimulus cytosol;membrane;nucleus enzyme regulator activity;metal ion binding;nucleotide binding;protein binding "Pf00226, Pf00684, Pf01556" 56445 ENSMUSG00000031701.6 Dnaja2 8 HSP90 chaperone cycle for steroid hormone receptors (SHR) Protein processing in endoplasmic reticulum 0 Low H3BLI5 Coiled-coil domain-containing protein 137 (Fragment) OS=Mus musculus OX=10090 GN=Ccdc137 PE=1 SV=1 0.06 1.263 4 1 3 1 241 27.1 10.21 870841.1875 1391212.875 1556505 1786539.375 1 1 1 1 ENSMUSG00000049957.14 11 0 High O88668 Protein CREG1 OS=Mus musculus OX=10090 GN=Creg1 PE=1 SV=1 0.002 5.087 13 2 3 2 220 24.4 6.42 16032.33789 1 regulation of biological process extracellular protein binding Pf13883 433375 ENSMUSG00000040713.12 Creg1 1 Neutrophil degranulation 0 High A0A0A6YWF9 Tyrosine-protein kinase receptor OS=Mus musculus OX=10090 GN=Ntrk3 PE=1 SV=1 0.005 3.241 1 1 3 1 839 94.3 6.55 42225.16895 27824.08008 2 1 cell differentiation;cellular component movement;development;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane catalytic activity;nucleotide binding;protein binding;receptor activity;signal transducer activity "Pf00047, Pf00069, Pf01462, Pf07679, Pf07714, Pf08205, Pf12799, Pf13306, Pf13855, Pf13895, Pf13927" 18213 ENSMUSG00000059146.12 Ntrk3 7 0 High A0A1B0GSG5 Ribonuclease inhibitor OS=Mus musculus OX=10090 GN=Rnh1 PE=1 SV=1 0 6.326 9 3 3 3 492 53.9 5.01 regulation of biological process cytoplasm;cytosol enzyme regulator activity;protein binding 107702 ENSMUSG00000038650.15 Rnh1 7 0 High Q921X9 Protein disulfide-isomerase A5 OS=Mus musculus OX=10090 GN=Pdia5 PE=1 SV=1 0.002 4.884 7 3 3 3 517 59.2 7.5 26776.75098 3 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;organelle lumen catalytic activity "Pf00085, Pf13098, Pf13899, Pf13905" 72599 ENSMUSG00000022844.7 Pdia5 16 0 High Q6PD21 SH2 domain-containing adapter protein B OS=Mus musculus OX=10090 GN=Shb PE=1 SV=2 0.002 4.087 4 2 3 2 503 54.7 8.78 cell death;cell differentiation;cell proliferation;development;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane protein binding Pf00017 230126 ENSMUSG00000044813.15 Shb 4 VEGFA-VEGFR2 Pathway; EPHB-mediated forward signaling 0 Medium E9Q892 DISP complex protein LRCH3 OS=Mus musculus OX=10090 GN=Lrch3 PE=1 SV=1 0.014 1.934 2 1 3 1 624 68.7 7.02 5611.943359 18473.91602 39144.10938 1 1 1 protein binding "Pf00307, Pf11971, Pf12799, Pf13855" ENSMUSG00000022801.13 16 0 High Q3UQ28 Peroxidasin homolog OS=Mus musculus OX=10090 GN=Pxdn PE=1 SV=2 0 5.859 3 3 3 3 1475 165 7.14 17304.44043 11937.33301 2 2 cell organization and biogenesis;metabolic process;response to stimulus endoplasmic reticulum;extracellular antioxidant activity;catalytic activity;metal ion binding;protein binding;structural molecule activity "Pf00047, Pf00093, Pf03098, Pf05825, Pf07679, Pf07686, Pf12799, Pf13855, Pf13895, Pf13927" 69675 ENSMUSG00000020674.17 Pxdn 12 Crosslinking of collagen fibrils 0 High Q9WUA5 Laforin OS=Mus musculus OX=10090 GN=Epm2a PE=1 SV=2 0 7.671 8 2 3 2 330 36.9 6.32 290678.1875 367686 85299.05078 69154.91406 2 1 1 2 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;endoplasmic reticulum;membrane;nucleus catalytic activity;protein binding;receptor activity;signal transducer activity "Pf00686, Pf00782, Pf05222" 13853 ENSMUSG00000055493.4 Epm2a 10 Glycogen synthesis 0 High A0A0R4IZY2 Cytochrome P450 2D26 OS=Mus musculus OX=10090 GN=Cyp2d26 PE=1 SV=1 0 6.862 7 3 3 3 500 56.9 6.64 42071.5625 1 metabolic process;response to stimulus endoplasmic reticulum;membrane catalytic activity;metal ion binding Pf00067 76279 ENSMUSG00000022445.6 Cyp2d26 15 Xenobiotics Steroid hormone biosynthesis; Serotonergic synapse 0 High A2API8 Paralemmin A kinase anchor protein OS=Mus musculus OX=10090 GN=Pakap PE=1 SV=1 0 6.47 3 2 3 2 921 101.5 5.2 cell organization and biogenesis;regulation of biological process;response to stimulus protein binding 11641 ENSMUSG00000038729.23 Akap2 4 0 High O54962 Barrier-to-autointegration factor OS=Mus musculus OX=10090 GN=Banf1 PE=1 SV=1 0.002 3.985 27 1 3 1 89 10.1 6.09 323077.8125 309360.8906 336229.7813 320371.6875 1 1 1 1 metabolic process;regulation of biological process chromosome;cytoplasm;cytosol;nucleus DNA binding;protein binding Pf02961 23825 ENSMUSG00000024844.14 Banf1 19 Clearance of Nuclear Envelope Membranes from Chromatin; Initiation of Nuclear Envelope Reformation; Nuclear Envelope Breakdown 0 High B2RQY6 BC035947 protein OS=Mus musculus OX=10090 GN=BC035947 PE=1 SV=1 0 6.001 3 2 3 2 695 76.5 7.94 234651.4375 1 membrane structural molecule activity Pf00429 269211 ENSMUSG00000090486.2 BC035947 1 0 High E9Q6B2 Coiled-coil domain-containing protein 85C OS=Mus musculus OX=10090 GN=Ccdc85c PE=1 SV=1 0 7.886 8 2 3 2 420 45.3 6.96 92338.02344 77597.16406 1 1 development Pf10226 668158 ENSMUSG00000084883.1 Ccdc85c 12 0 High A0A0G2JF45 Immunoglobulin kappa variable 14-130 (Fragment) OS=Mus musculus OX=10090 GN=Igkv14-130 PE=4 SV=4 0.002 4.498 11 1 3 1 117 13.1 4.56 485992.875 328692.5938 34273.46484 1 1 1 response to stimulus "Pf00047, Pf07679, Pf07686, Pf13927" 628072 ENSMUSG00000096461.5 Igkv14-130 6 0 High Q3UC82 DNA ligase OS=Mus musculus OX=10090 GN=Lig3 PE=1 SV=1 0.002 4.805 3 3 3 3 1011 112.6 8.98 29207.83398 35801.91406 40155.10938 1 1 1 cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus chromosome;mitochondrion;nucleus catalytic activity;DNA binding;metal ion binding;nucleotide binding;protein binding "Pf00533, Pf00645, Pf01068, Pf04675, Pf04679" 16882 ENSMUSG00000020697.16 Lig3 11 APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway; HDR through MMEJ (alt-NHEJ); Gap-filling DNA repair synthesis and ligation in TC-NER; Resolution of AP sites via the single-nucleotide replacement pathway 0 High Q91WN4 Kynurenine 3-monooxygenase OS=Mus musculus OX=10090 GN=Kmo PE=1 SV=1 0 7.582 8 3 3 3 479 54.5 8.88 metabolic process;response to stimulus membrane;mitochondrion catalytic activity;nucleotide binding Pf01494 98256 ENSMUSG00000039783.15 Kmo 1 Tryptophan catabolism Tryptophan metabolism; Metabolic pathways 0 High P31786 Acyl-CoA-binding protein OS=Mus musculus OX=10090 GN=Dbi PE=1 SV=2 0.002 3.982 38 2 3 2 87 10 8.82 6447.401855 23840.17188 60281.94141 1 1 2 Met-loss+Acetyl [N-Term] cell proliferation;defense response;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;Golgi;membrane;mitochondrion;nucleus protein binding Pf00887 13167 ENSMUSG00000026385.16 Dbi 1 Mitochondrial Fatty Acid Beta-Oxidation PPAR signaling pathway 0 High P61620 Protein transport protein Sec61 subunit alpha isoform 1 OS=Mus musculus OX=10090 GN=Sec61a1 PE=1 SV=2 0 6.778 6 3 3 3 476 52.2 8.06 cell growth;cell organization and biogenesis;development;response to stimulus;transport endoplasmic reticulum;membrane transporter activity "Pf00344, Pf10559" 53421 ENSMUSG00000030082.14 Sec61a1 6 XBP1(S) activates chaperone genes Phagosome; Protein export; Protein processing in endoplasmic reticulum 0 High Q91VL8 Telomeric repeat-binding factor 2-interacting protein 1 OS=Mus musculus OX=10090 GN=Terf2ip PE=1 SV=1 0.005 3.017 8 1 3 1 393 43.3 4.81 21020.00586 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus chromosome;cytoplasm;cytosol;nucleus DNA binding;protein binding "Pf08914, Pf11626" 57321 ENSMUSG00000033430.10 Terf2ip 8 Mus musculus biological processes; DNA Damage/Telomere Stress Induced Senescence; Meiotic Synapsis 0 High Q8BL97 Serine/arginine-rich splicing factor 7 OS=Mus musculus OX=10090 GN=Srsf7 PE=1 SV=1 0.002 3.803 9 2 3 1 267 30.8 11.9 62332.91797 137485.3594 30969.22266 91266.26953 1 2 1 2 metabolic process;regulation of biological process;transport cytoplasm;nucleus metal ion binding;protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 225027 Srsf7 17 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript Herpes simplex infection; Spliceosome 1 High Q9WV55 Vesicle-associated membrane protein-associated protein A OS=Mus musculus OX=10090 GN=Vapa PE=1 SV=2 0.005 3.007 10 2 3 1 249 27.8 8.4 7085.589844 1 cell death;cell organization and biogenesis;regulation of biological process;response to stimulus;transport cytoskeleton;endoplasmic reticulum;membrane;nucleus protein binding;signal transducer activity Pf00635 30960 ENSMUSG00000024091.8 Vapa 17 Neutrophil degranulation; Sphingolipid de novo biosynthesis Tight junction 0 High Q8BXZ1 Protein disulfide-isomerase TMX3 OS=Mus musculus OX=10090 GN=Tmx3 PE=1 SV=2 0 9.813 12 3 3 3 456 51.8 5.16 9615.713867 1 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cell surface;endoplasmic reticulum;membrane catalytic activity "Pf00085, Pf13098, Pf13848, Pf13899" 67988 ENSMUSG00000024614.6 Tmx3 18 Platelet degranulation 0 High Q05D44 Eukaryotic translation initiation factor 5B OS=Mus musculus OX=10090 GN=Eif5b PE=1 SV=2 0 7.15 4 3 3 3 1216 137.5 5.59 3989.839355 25742.07227 1 2 metabolic process;regulation of biological process cytoplasm catalytic activity;metal ion binding;nucleotide binding;RNA binding "Pf00009, Pf01926, Pf03144, Pf11987, Pf14578" 226982 ENSMUSG00000026083.12 Eif5b 1 Cap-dependent Translation Initiation; GTP hydrolysis and joining of the 60S ribosomal subunit RNA transport 0 High Q9DBB9 Carboxypeptidase N subunit 2 OS=Mus musculus OX=10090 GN=Cpn2 PE=1 SV=2 0.002 4.477 6 2 3 2 547 60.4 5.88 21088.87891 99978.875 11939.80273 131387.75 1 1 1 2 extracellular protein binding "Pf12799, Pf13306, Pf13855" 71756 ENSMUSG00000023176.8 Cpn2 16 Regulation of Complement cascade 0 High A0A0N4SUV6 Selenocysteine-specific elongation factor OS=Mus musculus OX=10090 GN=Eefsec PE=1 SV=1 0 5.531 11 2 3 2 534 58 7.33 174618.8867 144907.8125 92511.08594 8521.699219 3 2 1 1 metabolic process;regulation of biological process mitochondrion catalytic activity;nucleotide binding;RNA binding "Pf00009, Pf03144" ENSMUSG00000033216.9 6 0 High A2AFI3 "RNA-binding motif protein, X chromosome OS=Mus musculus OX=10090 GN=Rbmx PE=1 SV=1" 0.003 3.341 4 1 2 1 301 32.7 9.88 34907.60938 16161.01758 1 1 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus membrane;nucleus;spliceosomal complex DNA binding;protein binding;RNA binding "Pf00076, Pf08081, Pf13893, Pf14259" 19655 ENSMUSG00000031134.16 Rbmx X 0 High P11440 Cyclin-dependent kinase 1 OS=Mus musculus OX=10090 GN=Cdk1 PE=1 SV=3 0.003 3.594 8 2 2 1 297 34.1 8.43 5881.606934 1 cell death;cell differentiation;cell division;cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;mitochondrion;nucleus;organelle lumen catalytic activity;nucleotide binding;protein binding "Pf00069, Pf01636, Pf07714, Pf14531" 12534 ENSMUSG00000019942.13 Cdk1 10 "The role of GTSE1 in G2/M progression after G2 checkpoint; Loss of Nlp from mitotic centrosomes; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Ovarian tumor domain proteases; Recruitment of NuMA to mitotic centrosomes; MAPK6/MAPK4 signaling; Interleukin-20 family signaling; Cyclin A/B1/B2 associated events during G2/M transition; Resolution of Sister Chromatid Cohesion; MAPK3 (ERK1) activation; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Recruitment of mitotic centrosome proteins and complexes; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Depolymerisation of the Nuclear Lamina; Regulation of PLK1 Activity at G2/M Transition; Regulation of TP53 Degradation; Transcriptional regulation by RUNX2; APC/C:Cdc20 mediated degradation of Cyclin B; Condensation of Prophase Chromosomes; Phosphorylation of Emi1; Phosphorylation of the APC/C; Nuclear Pore Complex (NPC) Disassembly; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; G2/M DNA replication checkpoint; Activation of NIMA Kinases NEK9, NEK6, NEK7" Herpes simplex infection; p53 signaling pathway; Progesterone-mediated oocyte maturation; Epstein-Barr virus infection; Oocyte meiosis; Cell cycle; Gap junction; Viral carcinogenesis 0 Medium A0A494BAP3 Ferritin (Fragment) OS=Mus musculus OX=10090 GN=Fth1 PE=1 SV=1 0.018 1.812 12 1 2 1 59 6.8 6.77 5074.007324 25225.375 1 1 0 Medium P56475 Gamma-aminobutyric acid receptor subunit rho-1 OS=Mus musculus OX=10090 GN=Gabrr1 PE=2 SV=2 0.017 1.831 1 1 2 1 480 55.5 8.92 regulation of biological process;response to stimulus;transport membrane protein binding;receptor activity;signal transducer activity;transporter activity "Pf02931, Pf02932" 14408 ENSMUSG00000028280.9 Gabrr1 4 GABA A (rho) receptor activation Morphine addiction; Retrograde endocannabinoid signaling; GABAergic synapse; Nicotine addiction; Neuroactive ligand-receptor interaction 0 High Q99L45 Eukaryotic translation initiation factor 2 subunit 2 OS=Mus musculus OX=10090 GN=Eif2s2 PE=1 SV=1 0.004 2.583 3 1 2 1 331 38.1 5.8 30246.6582 1 cell proliferation;metabolic process cytoplasm metal ion binding;protein binding;RNA binding Pf01873 67204 ENSMUSG00000074656.12 Eif2s2 2 "L13a-mediated translational silencing of Ceruloplasmin expression; Recycling of eIF2:GDP; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ABC-family proteins mediated transport; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" RNA transport 0 High O55111 Desmoglein-2 OS=Mus musculus OX=10090 GN=Dsg2 PE=1 SV=3 0 7.884 2 1 2 1 1122 122.3 5.3 cell organization and biogenesis;regulation of biological process;response to stimulus cell surface;membrane metal ion binding;protein binding Pf00028 13511 ENSMUSG00000044393.15 Dsg2 18 Formation of the cornified envelope; Apoptotic cleavage of cell adhesion proteins Arrhythmogenic right ventricular cardiomyopathy (ARVC) 0 High Q8BZ03 Serine/threonine-protein kinase D2 OS=Mus musculus OX=10090 GN=Prkd2 PE=1 SV=1 0.005 3.24 4 2 2 2 875 96.5 6.89 cell death;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;Golgi;membrane;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00069, Pf00130, Pf00169, Pf07714, Pf14531" 101540 ENSMUSG00000041187.16 Prkd2 7 Sphingolipid de novo biosynthesis Rap1 signaling pathway; Aldosterone synthesis and secretion 0 High Q8R127 Saccharopine dehydrogenase-like oxidoreductase OS=Mus musculus OX=10090 GN=Sccpdh PE=1 SV=1 0.003 3.547 5 2 2 2 429 47.1 8.6 4792.757324 1 metabolic process membrane;mitochondrion;nucleus catalytic activity "Pf03435, Pf13460" 109232 ENSMUSG00000038936.13 Sccpdh 1 Platelet degranulation 0 High Q9Z1J3 "Cysteine desulfurase, mitochondrial OS=Mus musculus OX=10090 GN=Nfs1 PE=1 SV=3" 0.003 3.604 5 2 2 2 459 50.5 8.16 18392.03418 41764.25391 14170.95654 2 2 2 cell organization and biogenesis;metabolic process cytoplasm;cytosol;mitochondrion;nucleus;organelle lumen catalytic activity;metal ion binding;protein binding "Pf00266, Pf00282, Pf01212" 18041 ENSMUSG00000027618.17 Nfs1 2 Mitochondrial iron-sulfur cluster biogenesis; Molybdenum cofactor biosynthesis Thiamine metabolism; Metabolic pathways; Sulfur relay system 0 High Q80VD1 Protein FAM98B OS=Mus musculus OX=10090 GN=Fam98b PE=1 SV=1 0.004 2.719 3 1 2 1 429 45.3 8.5 25796.69922 26327.6582 14717.35449 1 1 1 metabolic process;regulation of biological process cytoplasm;nucleus catalytic activity;protein binding;RNA binding Pf10239 68215 ENSMUSG00000027349.5 Fam98b 2 0 High O35453 Serine protease hepsin OS=Mus musculus OX=10090 GN=Hpn PE=1 SV=3 0 6.895 5 2 2 2 436 46.8 7.43 32120.80273 11575.44336 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;extracellular;membrane catalytic activity;transporter activity "Pf00089, Pf09272, Pf09342, Pf15494" 15451 ENSMUSG00000001249.14 Hpn 7 MET Receptor Activation Viral carcinogenesis 0 High E9Q7G4 BAH and coiled-coil domain-containing protein 1 OS=Mus musculus OX=10090 GN=Bahcc1 PE=1 SV=1 0.006 2.419 0 1 2 1 2643 282.4 9.03 cell organization and biogenesis;regulation of biological process chromosome DNA binding Pf01426 268515 ENSMUSG00000039741.15 Bahcc1 11 0 High Q3UHC0 Trinucleotide repeat-containing gene 6C protein OS=Mus musculus OX=10090 GN=Tnrc6c PE=1 SV=2 0.006 2.394 1 1 2 1 1690 175.7 6.86 7077.316406 1 regulation of biological process protein binding;RNA binding "Pf00076, Pf00627, Pf10427, Pf12938, Pf13893, Pf14259" 217351 Tnrc6c 11 0 High Q9DBH5 Vesicular integral-membrane protein VIP36 OS=Mus musculus OX=10090 GN=Lman2 PE=1 SV=2 0.002 3.996 6 2 2 2 358 40.4 6.95 5503.42627 1 regulation of biological process;transport cell surface;Golgi;membrane metal ion binding;protein binding Pf03388 66890 ENSMUSG00000021484.7 Lman2 13 Protein processing in endoplasmic reticulum 0 High P84750 Ig kappa chain V region Mem5 (Fragment) OS=Mus musculus OX=10090 PE=1 SV=1 0.005 2.918 13 2 2 1 121 13.2 8.81 1 1 19389.90039 1 extracellular "Pf00047, Pf07679, Pf07686" 0 Medium P62876 "DNA-directed RNA polymerases I, II, and III subunit RPABC5 OS=Mus musculus OX=10090 GN=Polr2l PE=3 SV=1" 0.03 1.531 13 1 2 1 67 7.6 7.77 metabolic process nucleus catalytic activity;DNA binding;metal ion binding Pf01194 66491 ENSMUSG00000038489.8 Polr2l 7 mRNA Capping; RNA Polymerase II Transcription Initiation; Transcriptional regulation by small RNAs; RNA Polymerase II Pre-transcription Events; RNA Polymerase I Transcription Termination; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Formation of RNA Pol II elongation complex ; mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; RNA Pol II CTD phosphorylation and interaction with CE; FGFR2 alternative splicing; RNA Polymerase I Transcription Initiation; B-WICH complex positively regulates rRNA expression; mRNA Splicing - Minor Pathway; RNA Polymerase III Transcription Initiation From Type 1 Promoter; Dual incision in TC-NER; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA polymerase II transcribes snRNA genes; Formation of the Early Elongation Complex; TP53 Regulates Transcription of DNA Repair Genes; RNA Polymerase I Promoter Escape; Gap-filling DNA repair synthesis and ligation in TC-NER; RNA Polymerase I Chain Elongation; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA polymerase; Epstein-Barr virus infection; Metabolic pathways; Purine metabolism; Huntington's disease; Pyrimidine metabolism; Cytosolic DNA-sensing pathway 0 High Q3ULB1 Testin OS=Mus musculus OX=10090 GN=Tes PE=1 SV=1 0.002 5.162 6 2 2 2 410 46.6 7.87 14344.88379 6542.230469 1 1 regulation of biological process cytoplasm;cytosol;membrane;nucleus metal ion binding;protein binding;RNA binding "Pf00412, Pf06297" 21753 ENSMUSG00000029552.19 Tes 6 0 High Q921M3 Splicing factor 3B subunit 3 OS=Mus musculus OX=10090 GN=Sf3b3 PE=1 SV=1 0.006 2.411 1 1 2 1 1217 135.5 5.26 18249.58008 6004.794922 1 1 metabolic process;regulation of biological process nucleus;spliceosomal complex protein binding;RNA binding "Pf03178, Pf10433" 101943 ENSMUSG00000033732.10 Sf3b3 8 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway Spliceosome 0 High Q8CC86 Nicotinate phosphoribosyltransferase OS=Mus musculus OX=10090 GN=Naprt PE=1 SV=1 0.005 2.905 3 1 2 1 538 58.2 6.46 metabolic process;response to stimulus cytoplasm;cytosol catalytic activity Pf04095 223646 ENSMUSG00000022574.6 Naprt1; Naprt 15 Neutrophil degranulation; Nicotinamide salvaging Metabolic pathways; Nicotinate and nicotinamide metabolism 0 High Q6NZQ4 PAX-interacting protein 1 OS=Mus musculus OX=10090 GN=Paxip1 PE=1 SV=1 0.003 3.579 3 2 2 2 1056 119.2 7.2 6379.657715 1 cell differentiation;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus chromosome;nucleus protein binding "Pf00533, Pf12738" 55982 ENSMUSG00000002221.11 Paxip1 5 Nonhomologous End-Joining (NHEJ) 0 High Q8BGQ4 Protein O-mannosyl-transferase 2 OS=Mus musculus OX=10090 GN=Pomt2 PE=1 SV=1 0 5.492 3 2 2 2 820 92.3 9.8 metabolic process;response to stimulus endoplasmic reticulum;membrane catalytic activity "Pf02366, Pf02815" 217734 ENSMUSG00000034126.4 Pomt2 12 O-linked glycosylation Other types of O-glycan biosynthesis 0 High I7HLV5 Novel protein (Fragment) OS=Mus musculus OX=10090 GN=Fam3a PE=1 SV=1 0 5.878 15 2 2 2 199 21.8 8.28 defense response;response to stimulus extracellular;membrane 66294 ENSMUSG00000031399.15 Fam3a X 0 High J3QPC8 "Troponin T, slow skeletal muscle OS=Mus musculus OX=10090 GN=Tnnt1 PE=1 SV=1" 0.003 3.658 8 2 2 1 261 31.3 6.39 regulation of biological process Pf00992 ENSMUSG00000064179.13 7 0 Medium A0A0A0MQC5 Tetratricopeptide repeat protein 39A OS=Mus musculus OX=10090 GN=Ttc39a PE=4 SV=1 0.018 1.798 4 1 2 1 189 20.8 5.71 Pf10300 230603 ENSMUSG00000028555.15 Ttc39a 4 0 High O08705 Sodium/bile acid cotransporter OS=Mus musculus OX=10090 GN=Slc10a1 PE=1 SV=1 0.003 3.382 4 1 2 1 362 39.4 9.03 transport membrane transporter activity "Pf01758, Pf13593" 20493 ENSMUSG00000021135.8 Slc10a1 12 Recycling of bile acids and salts Bile secretion 0 High O70546 Lysine-specific demethylase 6A OS=Mus musculus OX=10090 GN=Kdm6a PE=1 SV=2 0.004 2.652 1 1 2 1 1401 154.3 7.39 6448.578613 1 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus nucleus catalytic activity;DNA binding;metal ion binding;protein binding "Pf00515, Pf02373, Pf05109, Pf13414, Pf13424, Pf13431, Pf13432" 22289 ENSMUSG00000037369.16 Kdm6a X HDMs demethylate histones Transcriptional misregulation in cancer 0 High Q9QUI0 Transforming protein RhoA OS=Mus musculus OX=10090 GN=Rhoa PE=1 SV=1 0.003 3.633 8 1 2 1 193 21.8 6.1 11480.29297 5109.416992 1 1 cell differentiation;cell division;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;endosome;membrane;mitochondrion;nucleus catalytic activity;nucleotide binding;protein binding "Pf00025, Pf00071, Pf08477" 11848 ENSMUSG00000007815.13 Rhoa 9 "RHO GTPases activate KTN1; PCP/CE pathway; Ovarian tumor domain proteases; ERBB2 Regulates Cell Motility; G beta:gamma signalling through PI3Kgamma; RHO GTPases Activate Rhotekin and Rhophilins; Sema4D induced cell migration and growth-cone collapse; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; Rho GTPase cycle; Sema4D mediated inhibition of cell attachment and migration; GPVI-mediated activation cascade; EPHB-mediated forward signaling; EPHA-mediated growth cone collapse; RHO GTPases activate PKNs; SLIT2:ROBO1 increases RHOA activity; VEGFA-VEGFR2 Pathway; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition); RHO GTPases activate CIT; Neutrophil degranulation; Axonal growth stimulation; Axonal growth inhibition (RHOA activation); RHO GTPases Activate ROCKs; RHO GTPases Activate Formins; G alpha (12/13) signalling events; PI3K/AKT activation" Oxytocin signaling pathway; Leukocyte transendothelial migration; Endocytosis; mTOR signaling pathway; Wnt signaling pathway; T cell receptor signaling pathway; Phospholipase D signaling pathway; Regulation of actin cytoskeleton; Pancreatic secretion; MicroRNAs in cancer; Ras signaling pathway; Focal adhesion; NOD-like receptor signaling pathway; Chemokine signaling pathway; Platelet activation; Tuberculosis; Axon guidance; Adherens junction; Sphingolipid signaling pathway; Pertussis; Proteoglycans in cancer; Neurotrophin signaling pathway; cGMP-PKG signaling pathway; TGF-beta signaling pathway; Rap1 signaling pathway; Pathways in cancer; cAMP signaling pathway; Vascular smooth muscle contraction; Tight junction; Colorectal cancer; Viral carcinogenesis; Bacterial invasion of epithelial cells 0 High O89051 Integral membrane protein 2B OS=Mus musculus OX=10090 GN=Itm2b PE=1 SV=1 0.004 3.475 11 2 2 2 266 30.2 5.3 59053.44141 55385.82813 26118.02734 1 1 1 regulation of biological process;response to stimulus endosome;extracellular;Golgi;membrane nucleotide binding;protein binding Pf04089 16432 ENSMUSG00000022108.7 Itm2b 14 0 High Q925B0 PRKC apoptosis WT1 regulator protein OS=Mus musculus OX=10090 GN=Pawr PE=1 SV=2 0.002 4.14 19 2 2 2 333 35.9 5.92 cell death;cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;membrane;nucleus protein binding;transporter activity "Pf01544, Pf05911, Pf08614" 114774 ENSMUSG00000035873.8 Pawr 10 0 High A0A1B0GT54 RuvB-like helicase (Fragment) OS=Mus musculus OX=10090 GN=Ruvbl2 PE=1 SV=1 0.007 2.262 9 1 2 1 134 14.2 10.43 metabolic process;regulation of biological process;response to stimulus nucleus catalytic activity;nucleotide binding "Pf00004, Pf03796, Pf06068, Pf06414, Pf06745, Pf07726, Pf07728, Pf13481" ENSMUSG00000003868.14 7 0 Medium F8WHX2 Copper homeostasis protein cutC homolog OS=Mus musculus OX=10090 GN=Cutc PE=1 SV=1 0.013 2.01 5 1 2 1 262 27.9 7.94 9753.306641 50820.30078 18029.49805 15236.77051 1 1 1 1 cell organization and biogenesis cytoplasm;cytosol;nucleus metal ion binding Pf03932 66388 ENSMUSG00000025193.14 Cutc 19 0 High P11859 Angiotensinogen OS=Mus musculus OX=10090 GN=Agt PE=1 SV=1 0.006 2.401 3 1 2 1 477 52 5.44 cell differentiation;cell growth;cell organization and biogenesis;cell proliferation;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;extracellular enzyme regulator activity;protein binding Pf00079 11606 Agt 8 0 High Q9EQF5 Dihydropyrimidinase OS=Mus musculus OX=10090 GN=Dpys PE=1 SV=2 0.003 3.37 8 2 2 2 519 56.7 7.2 57718.68359 73955.03125 45615.95313 30078.48633 1 1 1 1 cell organization and biogenesis;metabolic process cytoplasm;cytosol catalytic activity;metal ion binding;protein binding "Pf01979, Pf07969, Pf13147, Pf13594" 64705 ENSMUSG00000022304.12 Dpys 15 Pyrimidine catabolism Metabolic pathways; beta-Alanine metabolism; Pyrimidine metabolism; Drug metabolism - other enzymes; Pantothenate and CoA biosynthesis 0 Medium Q60631 Growth factor receptor-bound protein 2 OS=Mus musculus OX=10090 GN=Grb2 PE=1 SV=1 0.019 1.774 3 1 2 1 217 25.2 6.32 cell differentiation;cell organization and biogenesis;cellular component movement;defense response;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;endosome;Golgi;membrane;nucleus catalytic activity;protein binding;RNA binding "Pf00017, Pf00018, Pf07653, Pf14604" 14784 ENSMUSG00000059923.13 Grb2 11 "MET activates PI3K/AKT signaling; Signal regulatory protein family interactions; NCAM signaling for neurite out-growth; Signal attenuation; MET activates RAS signaling; FRS-mediated FGFR3 signaling; SHC-mediated cascade:FGFR3; Downstream signal transduction; FRS-mediated FGFR2 signaling; RAF/MAP kinase cascade; SHC1 events in ERBB4 signaling; GRB2 events in EGFR signaling; Spry regulation of FGF signaling; GPVI-mediated activation cascade; Regulation of KIT signaling; SHC-mediated cascade:FGFR4; FRS-mediated FGFR4 signaling; FCERI mediated MAPK activation; PI-3K cascade:FGFR4; PI-3K cascade:FGFR3; RET signaling; Signalling to RAS; EGFR downregulation; Role of LAT2/NTAL/LAB on calcium mobilization; Regulation of signaling by CBL; CD28 dependent Vav1 pathway; SOS-mediated signalling; RHO GTPases Activate WASPs and WAVEs; GRB2:SOS provides linkage to MAPK signaling for Integrins ; MET activates RAP1 and RAC1; Cargo recognition for clathrin-mediated endocytosis; SHC-related events triggered by IGF1R; Interleukin-15 signaling; MET activates PTPN11; G beta:gamma signalling through PI3Kgamma; Interleukin receptor SHC signaling; SHC1 events in EGFR signaling; Negative regulation of MET activity; Interleukin-20 family signaling; Regulation of actin dynamics for phagocytic cup formation; EGFR Transactivation by Gastrin; DAP12 signaling; Tie2 Signaling; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; GAB1 signalosome; PI3K Cascade; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; SHC-mediated cascade:FGFR2; GRB2 events in ERBB2 signaling; PI3K events in ERBB2 signaling; PI-3K cascade:FGFR2; FRS-mediated FGFR1 signaling; MET receptor recycling; FCERI mediated Ca+2 mobilization; SHC-mediated cascade:FGFR1; PI-3K cascade:FGFR1" ErbB signaling pathway; FoxO signaling pathway; Acute myeloid leukemia; mTOR signaling pathway; T cell receptor signaling pathway; Phospholipase D signaling pathway; MAPK signaling pathway; MicroRNAs in cancer; Ras signaling pathway; Prolactin signaling pathway; Focal adhesion; Jak-STAT signaling pathway; Insulin signaling pathway; Endometrial cancer; Chemokine signaling pathway; Breast cancer; Signaling pathways regulating pluripotency of stem cells; Hepatitis B; Osteoclast differentiation; Non-small cell lung cancer; B cell receptor signaling pathway; Dorso-ventral axis formation; Proteoglycans in cancer; Neurotrophin signaling pathway; Pathways in cancer; Hepatitis C; Alcoholism; PI3K-Akt signaling pathway; Renal cell carcinoma; GnRH signaling pathway; Natural killer cell mediated cytotoxicity; Gap junction; Glioma; Fc epsilon RI signaling pathway; EGFR tyrosine kinase inhibitor resistance; Choline metabolism in cancer; Estrogen signaling pathway; Viral carcinogenesis; Chronic myeloid leukemia; Prostate cancer; Endocrine resistance 0 Low Q9CXU1 Mediator of RNA polymerase II transcription subunit 31 OS=Mus musculus OX=10090 GN=Med31 PE=1 SV=2 0.073 1.207 5 1 2 1 131 15.8 8.54 9531.976563 7386.555176 12539.40918 1 1 1 metabolic process;regulation of biological process nucleus catalytic activity;protein binding Pf05669 67279 ENSMUSG00000020801.8 Med31 11 Generic Transcription Pathway; Mus musculus biological processes; Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes 0 High P40936 Indolethylamine N-methyltransferase OS=Mus musculus OX=10090 GN=Inmt PE=1 SV=1 0.004 2.82 16 2 2 2 264 29.4 6.39 6563.768066 9421.369141 1 1 metabolic process;response to stimulus cytoplasm;cytosol catalytic activity Pf01234 21743 ENSMUSG00000003477.5 Inmt 6 Tryptophan metabolism; Selenocompound metabolism 0 Medium O35295 Transcriptional activator protein Pur-beta OS=Mus musculus OX=10090 GN=Purb PE=1 SV=3 0.013 1.971 4 2 2 1 324 33.9 5.43 12287.1748 19122.37305 9367.189453 15864.73145 1 1 1 1 cell death;cell differentiation;cell proliferation;metabolic process;regulation of biological process nucleus DNA binding;protein binding;RNA binding;translation regulator activity Pf04845 19291 ENSMUSG00000094483.2 Purb 11 0 High Q9Z2Z6 Mitochondrial carnitine/acylcarnitine carrier protein OS=Mus musculus OX=10090 GN=Slc25a20 PE=1 SV=1 0.004 2.864 7 2 2 2 301 33 9.11 18022.38867 81579.5625 16759.76758 35211.14453 1 1 1 1 transport cytosol;membrane;mitochondrion transporter activity Pf00153 57279 ENSMUSG00000032602.6 Slc25a20 9 Import of palmitoyl-CoA into the mitochondrial matrix 0 High Q9D3A8 Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein OS=Mus musculus OX=10090 GN=Nos1ap PE=1 SV=3 0.003 3.654 8 2 2 2 503 55.8 6.09 4064.884033 1 regulation of biological process cytoplasm;cytosol;membrane;mitochondrion;nucleus protein binding Pf00640 70729 ENSMUSG00000038473.14 Nos1ap 1 Circadian entrainment 0 High Q8BTV2 Cleavage and polyadenylation specificity factor subunit 7 OS=Mus musculus OX=10090 GN=Cpsf7 PE=1 SV=2 0.002 4.842 6 2 2 2 471 52 8 41954.0127 2 cell organization and biogenesis;metabolic process membrane;nucleus RNA binding "Pf00076, Pf14259" 269061 ENSMUSG00000034820.3 Cpsf7 19 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Processing of Intronless Pre-mRNAs; Cleavage of Growing Transcript in the Termination Region mRNA surveillance pathway 0 High E9Q3B1 RCC1 and BTB domain-containing protein 2 OS=Mus musculus OX=10090 GN=Rcbtb2 PE=1 SV=1 0.006 2.405 3 1 2 1 517 56.3 5.47 3462.693604 1 protein binding "Pf00415, Pf00651, Pf13540" ENSMUSG00000022106.14 14 0 High Q9R092 17-beta-hydroxysteroid dehydrogenase type 6 OS=Mus musculus OX=10090 GN=Hsd17b6 PE=1 SV=1 0.002 4.782 7 2 2 2 317 36.1 8.4 metabolic process endoplasmic reticulum;endosome;membrane catalytic activity Pf00106 27400 ENSMUSG00000025396.7 Hsd17b6 10 Steroid hormone biosynthesis; Retinol metabolism; Metabolic pathways 0 Medium A0A075B5S1 Immunoglobulin heavy variable 9-1 OS=Mus musculus OX=10090 GN=Ighv9-1 PE=4 SV=1 0.011 2.156 15 1 2 1 98 11.1 7.94 1 2 407559.8438 22303.59766 1 1 "Pf00047, Pf07686" ENSMUSG00000096805.2 12 0 High Q9JLJ5 Elongation of very long chain fatty acids protein 1 OS=Mus musculus OX=10090 GN=Elovl1 PE=1 SV=1 0.004 2.641 5 1 2 1 279 32.7 9.63 Acetyl [N-Term] metabolic process endoplasmic reticulum;membrane catalytic activity Pf01151 54325 ENSMUSG00000006390.15 Elovl1 4 Synthesis of very long-chain fatty acyl-CoAs; alpha-linolenic acid (ALA) metabolism; Linoleic acid (LA) metabolism Fatty acid elongation 0 High E9PZD2 MICAL-like protein 2 OS=Mus musculus OX=10090 GN=Micall2 PE=1 SV=1 0.005 3.187 5 2 2 2 926 98.7 9.76 cell organization and biogenesis;transport cytoplasm;cytoskeleton;endosome;membrane metal ion binding;protein binding "Pf00412, Pf12130" 231830 ENSMUSG00000036718.17 Micall2 5 0 High Q61553 Fascin OS=Mus musculus OX=10090 GN=Fscn1 PE=1 SV=4 0.002 4.63 5 2 2 2 493 54.5 6.89 11637.53613 2574.442139 145586.1628 1 1 2 cell organization and biogenesis;cellular component movement;regulation of biological process cytoplasm;cytoskeleton;cytosol;membrane protein binding;RNA binding "Pf06229, Pf06268" 14086 ENSMUSG00000029581.14 Fscn1 5 0 Low Q24JP3 Protein FAM178B OS=Mus musculus OX=10090 GN=Fam178b PE=2 SV=2 0.083 1.089 2 1 2 1 464 52.5 6.33 15841358 9231635 4559308.531 4891731.438 1 1 1 1 Pf14816 381337 Fam178b 1 0 High A2AJW4 "Protein phosphatase 1, regulatory subunit 3D OS=Mus musculus OX=10090 GN=Ppp1r3d PE=1 SV=1" 0.002 3.947 5 1 2 1 279 30.5 8.25 1 1 97084.75 265758.1563 36697.89063 1 1 1 metabolic process;regulation of biological process catalytic activity;protein binding Pf03370 228966 ENSMUSG00000049999.4 Ppp1r3d 2 Insulin signaling pathway; Insulin resistance 0 High Q62241 U1 small nuclear ribonucleoprotein C OS=Mus musculus OX=10090 GN=Snrpc PE=1 SV=1 0.006 2.433 11 1 2 1 159 17.4 9.67 cell organization and biogenesis;metabolic process nucleus;spliceosomal complex metal ion binding;protein binding;RNA binding Pf06220 20630 ENSMUSG00000024217.9 Snrpc 17 mRNA Splicing - Major Pathway Spliceosome 0 Low D3YTQ7 Lactase-like protein OS=Mus musculus OX=10090 GN=Lctl PE=3 SV=1 0.076 1.16 7 1 2 1 409 47.2 6.76 5974080 4375659 2892041.25 1 1 1 metabolic process endoplasmic reticulum;membrane catalytic activity Pf00232 235435 ENSMUSG00000032401.15 Lctl 9 0 High P50543 Protein S100-A11 OS=Mus musculus OX=10090 GN=S100a11 PE=1 SV=1 0 7.378 16 1 2 1 98 11.1 5.45 44993.12891 37910.17578 63871.26953 1 1 1 regulation of biological process cytoplasm;extracellular;nucleus metal ion binding;protein binding "Pf00036, Pf01023, Pf13499, Pf13833" 20195 ENSMUSG00000027907.4 S100a11 3 Neutrophil degranulation 0 High Q9D7P6 "Iron-sulfur cluster assembly enzyme ISCU, mitochondrial OS=Mus musculus OX=10090 GN=Iscu PE=1 SV=1" 0.004 2.592 15 2 2 2 168 18.1 9.29 25999.48242 16869.54883 9893.967773 1 1 1 cell organization and biogenesis;cellular homeostasis;metabolic process cytoplasm;cytosol;mitochondrion;organelle lumen catalytic activity;metal ion binding;protein binding;structural molecule activity Pf01592 66383 ENSMUSG00000025825.12 Iscu 5 Mitochondrial iron-sulfur cluster biogenesis 0 High Q4FK66 Pre-mRNA-splicing factor 38A OS=Mus musculus OX=10090 GN=Prpf38a PE=1 SV=1 0.002 4.903 6 2 2 2 312 37.4 10.01 120850.9553 73374.60156 2 1 metabolic process membrane;nucleus;spliceosomal complex RNA binding Pf03371 230596 ENSMUSG00000063800.5 Prpf38a 4 mRNA Splicing - Major Pathway Spliceosome 0 Low Q8BHB4 WD repeat-containing protein 3 OS=Mus musculus OX=10090 GN=Wdr3 PE=1 SV=1 0.062 1.251 1 1 2 1 942 105.7 6.64 metabolic process membrane;nucleus protein binding;RNA binding "Pf00400, Pf04003" 269470 ENSMUSG00000033285.15 Wdr3 3 Major pathway of rRNA processing in the nucleolus and cytosol Ribosome biogenesis in eukaryotes 0 High A0A494B870 Transmembrane protein 132E OS=Mus musculus OX=10090 GN=Tmem132e PE=4 SV=1 0.007 2.325 1 1 2 1 982 106.9 6.04 0 High P12246 Serum amyloid P-component OS=Mus musculus OX=10090 GN=Apcs PE=1 SV=2 0.003 3.74 9 1 2 1 224 26.2 6.35 cell organization and biogenesis;defense response;regulation of biological process;response to stimulus extracellular;nucleus metal ion binding;protein binding "Pf00354, Pf13385" 20219 ENSMUSG00000026542.6 Apcs 1 0 Medium A0A0A6YXK7 Centrosomal protein of 170 kDa (Fragment) OS=Mus musculus OX=10090 GN=Cep170 PE=1 SV=1 0.021 1.719 1 1 2 1 787 85.9 8.63 Pf15308 ENSMUSG00000057335.11 1 0 High Q00977 Gap junction beta-2 protein OS=Mus musculus OX=10090 GN=Gjb2 PE=1 SV=1 0.002 4.016 6 2 2 2 226 26.4 9.01 cell communication;cell organization and biogenesis;response to stimulus;transport cytoplasm;cytosol;membrane protein binding;transporter activity "Pf00029, Pf10582" 14619 ENSMUSG00000046352.7 Gjb2 14 Transport of connexons to the plasma membrane 0 High Q9WUR2 "Enoyl-CoA delta isomerase 2, mitochondrial OS=Mus musculus OX=10090 GN=Eci2 PE=1 SV=2" 0.002 3.793 4 1 2 1 391 43.2 8.92 50963.57813 27647.17773 1 1 metabolic process membrane;mitochondrion;organelle lumen catalytic activity;protein binding "Pf00378, Pf00887" 23986 ENSMUSG00000021417.14 Eci2 13 Beta-oxidation of very long chain fatty acids Fatty acid degradation; Peroxisome 0 High Q9DB77 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Mus musculus OX=10090 GN=Uqcrc2 PE=1 SV=1" 0 6.488 6 2 2 2 453 48.2 9.25 60209.95703 1 metabolic process;transport membrane;mitochondrion catalytic activity;metal ion binding;protein binding "Pf00675, Pf05193" 67003 ENSMUSG00000030884.12 Uqcrc2 7 Respiratory electron transport Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 High Q05186 Reticulocalbin-1 OS=Mus musculus OX=10090 GN=Rcn1 PE=1 SV=1 0.003 3.7 6 2 2 2 325 38.1 4.84 7525.886719 6163.580566 5766.464355 1 1 1 endoplasmic reticulum;organelle lumen metal ion binding Pf13499 19672 ENSMUSG00000005973.6 Rcn1 2 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation 0 High Q0VBK4 "Cholinergic receptor, nicotinic, alpha polypeptide 3 OS=Mus musculus OX=10090 GN=Chrna3 PE=2 SV=1" 0 6.797 6 2 2 2 504 57.6 5.94 cell communication;cell organization and biogenesis;regulation of biological process;response to stimulus;transport membrane protein binding;receptor activity;signal transducer activity;transporter activity "Pf02931, Pf02932" 110834 ENSMUSG00000032303.7 Chrna3 9 Highly calcium permeable postsynaptic nicotinic acetylcholine receptors; Highly calcium permeable nicotinic acetylcholine receptors; Highly sodium permeable acetylcholine nicotinic receptors Cholinergic synapse; Neuroactive ligand-receptor interaction 0 Medium Q9CXI5 Mesencephalic astrocyte-derived neurotrophic factor OS=Mus musculus OX=10090 GN=Manf PE=1 SV=1 0.024 1.61 8 1 2 1 179 20.4 8.07 12191.40234 1 cell differentiation;cell organization and biogenesis;regulation of biological process;response to stimulus endoplasmic reticulum;extracellular;nucleus protein binding;RNA binding Pf10208 74840 Manf 9 0 High A0A452J8C1 Ras-related protein Rab-18 OS=Mus musculus OX=10090 GN=Rab18 PE=1 SV=1 0.002 4.197 11 2 2 2 194 22 9.04 20582.92578 14221.88965 46966.18555 1 1 2 0 Medium Q8C0Y0 Serine/threonine-protein phosphatase 4 regulatory subunit 4 OS=Mus musculus OX=10090 GN=Ppp4r4 PE=1 SV=2 0.022 1.64 1 1 2 1 875 99.4 7.71 177244.7969 151105.6563 273012.8438 1 1 1 regulation of biological process cytoplasm;cytosol enzyme regulator activity;protein binding 74521 ENSMUSG00000021209.12 Ppp4r4 12 0 Medium Q8R5H1 Ubiquitin carboxyl-terminal hydrolase 15 OS=Mus musculus OX=10090 GN=Usp15 PE=1 SV=1 0.04 1.403 2 1 2 1 981 112.3 5.17 8011.963379 12012.81055 2619.003418 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;mitochondrion;nucleus catalytic activity;protein binding "Pf00443, Pf06337, Pf13423, Pf14533, Pf14836" 14479 ENSMUSG00000020124.10 Usp15 10 Ub-specific processing proteases 0 Low Q61768 Kinesin-1 heavy chain OS=Mus musculus OX=10090 GN=Kif5b PE=1 SV=3 0.069 1.233 1 1 2 1 963 109.5 6.44 5650.222168 4060.57373 1 1 cell differentiation;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;cytosol;membrane catalytic activity;motor activity;nucleotide binding;protein binding "Pf00225, Pf01576, Pf02463, Pf03999, Pf04111, Pf04156, Pf05483, Pf05557, Pf05622, Pf06160, Pf07111, Pf07888, Pf10174, Pf12128, Pf13514, Pf14915" 16573 ENSMUSG00000006740.13 Kif5b 18 Endocytosis; Dopaminergic synapse 0 High Q7M6Z4 Kinesin-like protein KIF27 OS=Mus musculus OX=10090 GN=Kif27 PE=1 SV=1 0.003 3.334 1 2 2 1 1394 158.9 7.14 cell organization and biogenesis;cellular component movement;regulation of biological process cytoplasm;cytoskeleton catalytic activity;motor activity;nucleotide binding;protein binding "Pf00225, Pf02463, Pf05557, Pf09726, Pf09731" 75050 ENSMUSG00000060176.3 Kif27 13 0 High Q99J99 3-mercaptopyruvate sulfurtransferase OS=Mus musculus OX=10090 GN=Mpst PE=1 SV=4 0.002 4.404 13 2 2 2 297 33.1 6.47 82495.35938 6298.87207 47458.70703 1 1 2 0 High O35988 Syndecan-4 OS=Mus musculus OX=10090 GN=Sdc4 PE=1 SV=1 0.002 4.645 15 2 2 2 198 21.5 4.41 43467.43359 1 cell organization and biogenesis;regulation of biological process;response to stimulus cell surface;extracellular;membrane;organelle lumen protein binding;receptor activity;signal transducer activity Pf01034 20971 ENSMUSG00000017009.3 Sdc4 2 HS-GAG degradation; A tetrasaccharide linker sequence is required for GAG synthesis; Cell surface interactions at the vascular wall; Signaling by GPCR; Retinoid metabolism and transport; HS-GAG biosynthesis; Syndecan interactions Cell adhesion molecules (CAMs); Proteoglycans in cancer; ECM-receptor interaction 0 Medium Q8VDP4 Cell cycle and apoptosis regulator protein 2 OS=Mus musculus OX=10090 GN=Ccar2 PE=1 SV=2 0.02 1.673 1 1 2 1 922 102.9 5.25 24555.36523 21362.06836 34804.66797 8195.000977 1 1 1 1 cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus;organelle lumen;spliceosomal complex enzyme regulator activity;protein binding;RNA binding "Pf14443, Pf14444" 219158 ENSMUSG00000033712.5 2610301G19Rik; Ccar2 14 Regulation of HSF1-mediated heat shock response 0 High Q9Z1Z0 General vesicular transport factor p115 OS=Mus musculus OX=10090 GN=Uso1 PE=1 SV=2 0.003 3.576 2 2 2 2 959 106.9 4.93 18243.10303 2 cell organization and biogenesis;transport cytoplasm;cytosol;endoplasmic reticulum;Golgi;membrane protein binding;RNA binding;transporter activity "Pf04869, Pf04871, Pf13514" 56041 ENSMUSG00000029407.10 Uso1 5 COPI-mediated anterograde transport; COPII (Coat Protein 2) Mediated Vesicle Transport 0 High P70206 Plexin-A1 OS=Mus musculus OX=10090 GN=Plxna1 PE=1 SV=1 0.003 3.624 2 2 2 2 1894 211 6.9 4169.421875 1 cell growth;cellular component movement;regulation of biological process;response to stimulus membrane protein binding;receptor activity;signal transducer activity "Pf01403, Pf01437, Pf01833, Pf08337" 18844 ENSMUSG00000030084.11 Plxna1 6 CRMPs in Sema3A signaling; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion; Other semaphorin interactions; Sema3A PAK dependent Axon repulsion Axon guidance 0 Medium Q9JII6 Aldo-keto reductase family 1 member A1 OS=Mus musculus OX=10090 GN=Akr1a1 PE=1 SV=3 0.032 1.477 4 1 2 1 325 36.6 7.39 Met-loss+Acetyl [N-Term] metabolic process cytosol;membrane catalytic activity Pf00248 58810 ENSMUSG00000028692.14 Akr1a1 4 Glutathione conjugation; Catabolism of glucuronate to xylulose-5-phosphate Metabolic pathways; Glycolysis / Gluconeogenesis; Glycerolipid metabolism; Pentose and glucuronate interconversions 0 High A0A2I3BPG9 "Ribosomal protein L36A, pseudogene 1 OS=Mus musculus OX=10090 GN=Rpl36a-ps1 PE=3 SV=1" 0.007 2.33 8 1 2 1 106 12.4 10.51 28177.24414 1 0 High Q6ZQ38 Cullin-associated NEDD8-dissociated protein 1 OS=Mus musculus OX=10090 GN=Cand1 PE=1 SV=2 0.007 2.313 1 1 2 1 1230 136.2 5.78 15876.92578 3823.693604 1 1 Met-loss+Acetyl [N-Term] cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;cytosol;Golgi;membrane;nucleus protein binding "Pf08623, Pf12755, Pf13513" 71902 ENSMUSG00000020114.12 Cand1 10 Neddylation; Neutrophil degranulation; Iron uptake and transport 0 Medium G3UWL2 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (Fragment) OS=Mus musculus OX=10090 GN=Ppp2r1a PE=1 SV=1 0.011 2.115 11 1 2 1 143 15.9 4.73 17464.75391 79498.74219 18325.51172 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process cytosol catalytic activity;enzyme regulator activity;protein binding ENSMUSG00000007564.14 17 0 High Q5SVW9 Transmembrane emp24 domain-containing protein 4 (Fragment) OS=Mus musculus OX=10090 GN=Tmed4 PE=1 SV=1 0.005 3.141 6 1 2 1 170 19.1 6.64 16681.99805 10848.42188 1 1 regulation of biological process;transport endoplasmic reticulum;membrane signal transducer activity Pf01105 103694 ENSMUSG00000004394.12 Tmed4 11 0 High E9PWN8 Glycosyltransferase 8 domain-containing protein 2 OS=Mus musculus OX=10090 GN=Glt8d2 PE=4 SV=1 0.005 3.071 8 2 2 2 363 40.7 8.47 catalytic activity Pf01501 ENSMUSG00000020251.13 10 0 High Q3TNA1 Xylulose kinase OS=Mus musculus OX=10090 GN=Xylb PE=1 SV=1 0 6.028 5 2 2 2 551 59.5 6.9 68625.76563 58369.42578 1 1 metabolic process cytoplasm catalytic activity;nucleotide binding "Pf00370, Pf02782" 102448 ENSMUSG00000035769.9 Xylb 9 Catabolism of glucuronate to xylulose-5-phosphate Metabolic pathways; Pentose and glucuronate interconversions 0 Medium A0A571BEV2 Predicted gene 8251 OS=Mus musculus OX=10090 GN=Gm8251 PE=4 SV=1 0.031 1.487 0 1 2 1 6590 746.9 9.54 8077.69873 2558715.445 12527.06738 1 1 1 0 High Q99J09 Methylosome protein 50 OS=Mus musculus OX=10090 GN=Wdr77 PE=1 SV=1 0 10.845 5 1 2 1 342 36.9 5.27 cell differentiation;regulation of biological process cytoplasm;cytosol;Golgi;nucleus DNA binding;nucleotide binding;protein binding "Pf00400, Pf11768" 70465 ENSMUSG00000000561.14 Wdr77 3 RMTs methylate histone arginines; snRNP Assembly 0 Medium Q8R2N2 U3 small nucleolar RNA-associated protein 4 homolog OS=Mus musculus OX=10090 GN=Utp4 PE=2 SV=3 0.026 1.575 1 1 2 1 686 76.9 8.87 10248.80664 1 metabolic process;regulation of biological process chromosome;nucleus protein binding;RNA binding "Pf00400, Pf07433" 21771 ENSMUSG00000041438.8 Cirh1a; Utp4 8 Major pathway of rRNA processing in the nucleolus and cytosol Ribosome biogenesis in eukaryotes 0 High Q60932 Voltage-dependent anion-selective channel protein 1 OS=Mus musculus OX=10090 GN=Vdac1 PE=1 SV=3 0.004 2.795 4 1 2 1 296 32.3 8.43 cell communication;cell death;cell differentiation;defense response;regulation of biological process;response to stimulus;transport membrane;mitochondrion;nucleus nucleotide binding;protein binding;transporter activity Pf01459 22333 ENSMUSG00000020402.11 Vdac1 11 Pink/Parkin Mediated Mitophagy NOD-like receptor signaling pathway; HTLV-I infection; Huntington's disease; Parkinson's disease; cGMP-PKG signaling pathway; Calcium signaling pathway; Influenza A 0 High K3W4Q8 Basigin OS=Mus musculus OX=10090 GN=Bsg PE=1 SV=1 0.002 4.738 6 1 2 1 218 24.1 5.36 16713.31396 19013.04102 22720.8457 2 1 2 cell organization and biogenesis membrane;mitochondrion protein binding "Pf00047, Pf07679, Pf13927" 12215 ENSMUSG00000023175.15 Bsg 10 0 Low G5E880 Lymphoid-restricted membrane protein OS=Mus musculus OX=10090 GN=Lrmp PE=1 SV=1 0.07 1.231 3 1 2 1 539 59.4 5.08 chromosome;cytoplasm;cytoskeleton;endoplasmic reticulum;membrane;nucleus protein binding Pf05781 16970 ENSMUSG00000030263.13 Lrmp 6 Neutrophil degranulation 0 High A0A1B0GRU8 Pre-mRNA-processing factor 40 homolog A OS=Mus musculus OX=10090 GN=Prpf40a PE=1 SV=1 0.005 3.187 2 2 2 2 926 105.5 7.99 786178.6875 1060222.375 299855.4063 1 1 1 cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process cytosol;membrane;nucleus;spliceosomal complex protein binding;RNA binding "Pf00397, Pf01846" 56194 ENSMUSG00000061136.14 Prpf40a 2 0 High P62192 26S proteasome regulatory subunit 4 OS=Mus musculus OX=10090 GN=Psmc1 PE=1 SV=1 0.002 3.772 5 2 2 1 440 49.2 6.21 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;nucleus;proteasome catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00004, Pf00910, Pf01078, Pf05496, Pf05673, Pf05729, Pf07724, Pf07726, Pf07728, Pf13191, Pf13401" 19179 ENSMUSG00000021178.8 Psmc1 12 The role of GTSE1 in G2/M progression after G2 checkpoint; CDT1 association with the CDC6:ORC:origin complex; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Degradation of beta-catenin by the destruction complex; Autodegradation of the E3 ubiquitin ligase COP1; UCH proteinases; MAPK6/MAPK4 signaling; SCF-beta-TrCP mediated degradation of Emi1; CDK-mediated phosphorylation and removal of Cdc6; Separation of Sister Chromatids; SCF(Skp2)-mediated degradation of p27/p21; GLI3 is processed to GLI3R by the proteasome; Ub-specific processing proteases; Regulation of ornithine decarboxylase (ODC); Activation of NF-kappaB in B cells; Degradation of GLI1 by the proteasome; FCERI mediated NF-kB activation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Hedgehog ligand biogenesis; Downstream TCR signaling; Autodegradation of Cdh1 by Cdh1:APC/C; Regulation of RAS by GAPs; N-glycan trimming in the ER and Calnexin/Calreticulin cycle; Interleukin-1 family signaling; Asymmetric localization of PCP proteins; G2/M Checkpoints; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Regulation of PTEN stability and activity; Ubiquitin-dependent degradation of Cyclin D1; NIK-->noncanonical NF-kB signaling; Removal of licensing factors from origins; M/G1 Transition; Interleukin-20 family signaling; Regulation of RUNX2 expression and activity; Cross-presentation of soluble exogenous antigens (endosomes); ABC-family proteins mediated transport; APC/C:Cdc20 mediated degradation of Securin; Regulation of DNA replication; Dectin-1 mediated noncanonical NF-kB signaling; Antigen processing: Ubiquitination & Proteasome degradation; Orc1 removal from chromatin; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of RUNX3 expression and activity; Hedgehog 'on' state; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Degradation of DVL; Degradation of AXIN Proteasome; Epstein-Barr virus infection; Viral carcinogenesis 0 Low F8VPV0 Pericentrin OS=Mus musculus OX=10090 GN=Pcnt PE=1 SV=1 0.08 1.116 1 1 2 1 2916 331.1 5.38 787572.4375 3777608.75 1529265.25 1 1 1 cell organization and biogenesis;cell proliferation;cellular component movement;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane protein binding;structural molecule activity "Pf09731, Pf10495" 18541 ENSMUSG00000001151.10 Pcnt 10 Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes 0 High A0A5F8MPM3 Olfactomedin-like 1 OS=Mus musculus OX=10090 GN=Olfml1 PE=4 SV=1 0.002 4.859 8 2 2 2 232 26.3 6.4 0 High P53986 Monocarboxylate transporter 1 OS=Mus musculus OX=10090 GN=Slc16a1 PE=1 SV=1 0 6.718 4 2 2 2 493 53.2 7.47 73982.24219 12819.4248 146673.9063 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport membrane;mitochondrion protein binding;transporter activity "Pf00083, Pf07690" 20501 ENSMUSG00000032902.1 Slc16a1 3 Basigin interactions; Proton-coupled monocarboxylate transport; Pyruvate metabolism 0 High Q80ZM5 "H1 histone family, member X OS=Mus musculus OX=10090 GN=H1f10 PE=1 SV=1" 0.005 2.956 5 1 2 1 188 20.1 11.22 2620.782715 1 cell organization and biogenesis chromosome;nucleus DNA binding;protein binding;RNA binding Pf00538 243529 ENSMUSG00000044927.6 H1fx 6 0 High Q3U3K9 Ancient ubiquitous protein 1 OS=Mus musculus OX=10090 GN=Aup1 PE=1 SV=1 0.003 3.354 3 1 2 1 439 49.3 9.25 metabolic process;regulation of biological process;transport cytoplasm;endoplasmic reticulum;membrane enzyme regulator activity;protein binding Pf02845 11993 ENSMUSG00000068328.9 Aup1 6 0 Low A0A1D5RM97 Microtubule-associated serine/threonine-protein kinase 3 OS=Mus musculus OX=10090 GN=Mast3 PE=1 SV=1 0.06 1.268 1 1 2 1 1305 142.5 8.65 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00069, Pf00595, Pf07714, Pf08926, Pf13180, Pf14531" 546071 ENSMUSG00000031833.10; ENSMUSG00000110763.1 Mast3 8; CHR_MG190_MG3751_PATCH 0 High Q99JB8 Protein kinase C and casein kinase II substrate protein 3 OS=Mus musculus OX=10090 GN=Pacsin3 PE=1 SV=1 0.002 4.833 4 1 2 1 424 48.6 6.1 cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;cytosol;endosome;membrane catalytic activity;protein binding "Pf00018, Pf00611, Pf07653, Pf14604" 80708 ENSMUSG00000027257.13 Pacsin3 2 0 High Q9D8S4 "Oligoribonuclease, mitochondrial OS=Mus musculus OX=10090 GN=Rexo2 PE=1 SV=2" 0.002 4.403 12 2 2 2 237 26.7 7.15 18354.74121 11548.67285 5393.725586 2 1 1 metabolic process mitochondrion;nucleus;organelle lumen catalytic activity Pf00929 104444 ENSMUSG00000032026.7 Rexo2 9 Ribosome biogenesis in eukaryotes 0 High Q60865 Caprin-1 OS=Mus musculus OX=10090 GN=Caprin1 PE=1 SV=2 0 5.831 3 2 2 2 707 78.1 5.25 20721.14648 253434.2344 24874.83594 18476.61914 1 1 1 1 cell differentiation;regulation of biological process cytoplasm;cytosol;membrane RNA binding Pf12287 53872 ENSMUSG00000027184.14 Caprin1 2 0 Medium Q8R3L5 Solute carrier organic anion transporter family member 3A1 OS=Mus musculus OX=10090 GN=Slco3a1 PE=1 SV=1 0.013 2.026 1 1 2 1 710 76.7 7.05 transport cell surface;membrane protein binding;transporter activity "Pf03137, Pf07648, Pf07690" 108116 ENSMUSG00000025790.14 Slco3a1 7 Transport of organic anions 0 Medium P35278 Ras-related protein Rab-5C OS=Mus musculus OX=10090 GN=Rab5c PE=1 SV=2 0.042 1.381 5 1 2 1 216 23.4 8.41 10786.38867 4892.192383 20305.36523 1 1 1 cell organization and biogenesis;regulation of biological process;response to stimulus;transport endosome;membrane catalytic activity;nucleotide binding;protein binding "Pf00009, Pf00025, Pf00071, Pf04670, Pf08477" 19345 ENSMUSG00000019173.11 Rab5c 11 Neutrophil degranulation; Golgi Associated Vesicle Biogenesis Endocytosis; Ras signaling pathway; Tuberculosis; Phagosome; Vasopressin-regulated water reabsorption; Amoebiasis 0 High J3QNZ9 Immunoglobulin kappa variable 4-62 OS=Mus musculus OX=10090 GN=Igkv4-62 PE=1 SV=1 0.002 4.532 17 1 2 1 96 10.4 6.44 112422.1719 1 "Pf00047, Pf07679, Pf07686" ENSMUSG00000094262.2 6 0 High Q6PCN7 Helicase-like transcription factor OS=Mus musculus OX=10090 GN=Hltf PE=1 SV=1 0.002 4.167 3 2 2 2 1003 113.2 8.09 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus catalytic activity;DNA binding;metal ion binding;nucleotide binding;protein binding;RNA binding "Pf00097, Pf00176, Pf00271, Pf08797, Pf12678, Pf12861, Pf13445, Pf13639, Pf13920, Pf13923, Pf14634, Pf15227" 20585 ENSMUSG00000002428.12 Hltf 3 0 High Q9D0M5 "Dynein light chain 2, cytoplasmic OS=Mus musculus OX=10090 GN=Dynll2 PE=1 SV=1" 0 6.485 25 1 2 1 89 10.3 7.37 30062.56445 36138.0625 1 1 cell organization and biogenesis;cellular component movement;regulation of biological process;transport cytoplasm;cytoskeleton;membrane;nucleus catalytic activity;motor activity;protein binding Pf01221 68097 ENSMUSG00000020483.14 Dynll2 11 Activation of BMF and translocation to mitochondria; COPI-mediated anterograde transport; Macroautophagy; HSP90 chaperone cycle for steroid hormone receptors (SHR); Intraflagellar transport; Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal; Resolution of Sister Chromatid Cohesion; Separation of Sister Chromatids; COPI-independent Golgi-to-ER retrograde traffic; RHO GTPases Activate Formins; MHC class II antigen presentation Vasopressin-regulated water reabsorption 0 Low H3BLG5 Syntenin-1 (Fragment) OS=Mus musculus OX=10090 GN=Sdcbp PE=1 SV=1 0.063 1.25 4 1 2 1 249 26.8 7.42 4700.39502 1 cell communication;cell organization and biogenesis;regulation of biological process;response to stimulus protein binding "Pf00595, Pf13180" ENSMUSG00000028249.15 4 0 High Q9JKF1 Ras GTPase-activating-like protein IQGAP1 OS=Mus musculus OX=10090 GN=Iqgap1 PE=1 SV=2 0.004 2.815 1 2 2 1 1657 188.6 6.48 3142.455811 1 cell growth;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane;nucleus enzyme regulator activity;protein binding "Pf00307, Pf00616, Pf03836, Pf11016" 29875 ENSMUSG00000030536.10 Iqgap1 7 Nephrin family interactions; RHO GTPases activate IQGAPs; Neutrophil degranulation Regulation of actin cytoskeleton; Adherens junction; Proteoglycans in cancer 0 Medium P62317 Small nuclear ribonucleoprotein Sm D2 OS=Mus musculus OX=10090 GN=Snrpd2 PE=1 SV=1 0.023 1.635 8 1 2 1 118 13.5 9.91 8084.630859 20430.92773 25086.50586 11565.94824 1 1 1 1 cell organization and biogenesis;metabolic process cytoplasm;cytosol;nucleus;spliceosomal complex RNA binding Pf01423 107686 ENSMUSG00000040824.3 Snrpd2 7 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; snRNP Assembly Spliceosome 0 High A2AJI1 MAP7 domain-containing protein 1 OS=Mus musculus OX=10090 GN=Map7d1 PE=1 SV=1 0.005 2.936 2 1 2 1 774 85.7 9.95 6504.052246 27699.75195 1 1 cell organization and biogenesis cytoplasm;cytoskeleton;cytosol structural molecule activity 245877 ENSMUSG00000028849.17 Map7d1; Mtap7d1 4 0 High P62320 Small nuclear ribonucleoprotein Sm D3 OS=Mus musculus OX=10090 GN=Snrpd3 PE=1 SV=1 0 6.392 25 2 2 2 126 13.9 10.32 56102.86719 217616.8594 75233.78906 1 1 2 cell organization and biogenesis;metabolic process cytoplasm;cytosol;nucleus;spliceosomal complex protein binding;RNA binding Pf01423 67332 ENSMUSG00000020180.10 Snrpd3 10 mRNA Splicing - Minor Pathway; Cleavage of Growing Transcript in the Termination Region ; mRNA Splicing - Major Pathway; snRNP Assembly; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs; SLBP independent Processing of Histone Pre-mRNAs Spliceosome; Systemic lupus erythematosus 0 Medium A0A1L1STF9 SAFB-like transcription modulator OS=Mus musculus OX=10090 GN=Sltm PE=1 SV=1 0.022 1.659 1 1 2 1 664 72.6 5.55 3706.810059 1650.169678 1 1 RNA binding "Pf00076, Pf02037, Pf03344, Pf13893, Pf14259" ENSMUSG00000032212.10 9 0 High Q3UNZ8 Quinone oxidoreductase-like protein 2 OS=Mus musculus OX=10090 GN=Cryzl2 PE=1 SV=1 0.002 4.351 9 2 2 2 350 37.8 8.9 8568.996094 34799.54688 1 1 metabolic process mitochondrion catalytic activity "Pf00107, Pf08240, Pf13602" 226527 ENSMUSG00000033488.11 BC026585; Cryzl2 1 0 High P62274 40S ribosomal protein S29 OS=Mus musculus OX=10090 GN=Rps29 PE=1 SV=2 0.002 5.165 34 2 2 2 56 6.7 10.13 4103.340332 1 Met-loss [N-Term] metabolic process;regulation of biological process ribosome metal ion binding;structural molecule activity Pf00253 20090 ENSMUSG00000034892.8 Rps29 12 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High Q8R2M2 Deoxynucleotidyltransferase terminal-interacting protein 2 OS=Mus musculus OX=10090 GN=Dnttip2 PE=1 SV=1 0.005 2.929 2 1 2 1 758 84.2 6.44 metabolic process;regulation of biological process nucleus RNA binding Pf08698 99480 ENSMUSG00000039756.12 Dnttip2 3 0 Low E9PZU5 "Vomeronasal 2, receptor 96 OS=Mus musculus OX=10090 GN=Vmn2r96 PE=3 SV=2" 0.055 1.302 3 1 2 1 856 98.2 7.88 12963271 6950589.5 4236760.5 6616784.5 1 1 1 1 0 High Q8BU30 "Isoleucine--tRNA ligase, cytoplasmic OS=Mus musculus OX=10090 GN=Iars1 PE=1 SV=2" 0.005 2.925 2 2 2 2 1262 144.2 6.55 4056.275879 6339.984863 1 1 cell differentiation;metabolic process;regulation of biological process cytoplasm;cytosol;membrane catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00133, Pf01406, Pf08264, Pf09334" 105148 ENSMUSG00000037851.13 Iars 13 Aminoacyl-tRNA biosynthesis 0 High E9Q852 Afadin OS=Mus musculus OX=10090 GN=Afdn PE=1 SV=2 0.004 3.504 3 2 2 2 1805 204.4 6.24 cell differentiation;cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm protein binding "Pf00498, Pf00595, Pf00788, Pf01843" ENSMUSG00000068036.14 17 0 High A0A0A6YX73 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Mus musculus OX=10090 GN=Prkar2a PE=1 SV=1 0.002 4.936 4 1 2 1 380 43.1 4.93 1 1 131752.5352 64745.27832 76469.78906 1 1 1 regulation of biological process enzyme regulator activity;nucleotide binding "Pf00027, Pf02197" ENSMUSG00000032601.13 9 PKA activation; Signaling by GPCR; PKA activation in glucagon signalling; DARPP-32 events; Hedgehog 'off' state; Vasopressin regulates renal water homeostasis via Aquaporins; Factors involved in megakaryocyte development and platelet production 0 Medium A0A0U1RPB3 SEC23-interacting protein (Fragment) OS=Mus musculus OX=10090 GN=Sec23ip PE=4 SV=1 0.013 1.971 61 1 2 1 56 5.5 8.73 100673.8594 13538.71094 1 1 Met-loss+Acetyl [N-Term] ENSMUSG00000055319.8 7 COPII (Coat Protein 2) Mediated Vesicle Transport 0 Medium Q80Y37 "Heat shock transcription factor, Y-linked 2 OS=Mus musculus OX=10090 GN=Hsfy2 PE=2 SV=1" 0.029 1.545 3 1 2 1 392 44.2 6.7 46548.73828 1 regulation of biological process nucleus DNA binding Pf00447 71066 ENSMUSG00000045336.5 Hsfy2 1 0 High Q99KJ8 Dynactin subunit 2 OS=Mus musculus OX=10090 GN=Dctn2 PE=1 SV=3 0.002 3.785 7 2 2 2 402 44.1 5.26 82089.75 329669.1875 93238.97363 1 2 2 cell organization and biogenesis;cell proliferation;transport chromosome;cytoplasm;cytoskeleton;cytosol;membrane catalytic activity;motor activity;protein binding Pf04912 69654 ENSMUSG00000025410.10 Dctn2 10 Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; COPI-mediated anterograde transport; Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes; HSP90 chaperone cycle for steroid hormone receptors (SHR); COPI-independent Golgi-to-ER retrograde traffic; MHC class II antigen presentation Huntington's disease; Vasopressin-regulated water reabsorption 0 High A2AQD6 Protein ITPRID2 OS=Mus musculus OX=10090 GN=Itprid2 PE=1 SV=1 0.005 3.065 3 2 2 2 1219 133.4 5.21 cytoplasm;cytosol;membrane;nucleus protein binding "Pf14722, Pf14723" 70599 ENSMUSG00000027007.16 Ssfa2 2 0 High A0A0B4J1M0 Immunoglobulin heavy variable 1-77 OS=Mus musculus OX=10090 GN=Ighv1-77 PE=1 SV=1 0.005 3.101 14 1 2 1 98 10.7 9.22 "Pf00047, Pf07686" 16061 ENSMUSG00000096452.2 Igh-VJ558 12 0 Medium Q3V3R1 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Mus musculus OX=10090 GN=Mthfd1l PE=1 SV=2" 0.031 1.482 3 1 2 1 977 105.7 7.02 metabolic process membrane;mitochondrion catalytic activity;nucleotide binding;protein binding "Pf00763, Pf01268, Pf02882" 270685 ENSMUSG00000040675.17 Mthfd1l 10 Metabolism of folate and pterines Metabolic pathways; One carbon pool by folate 0 High S4R1V0 PDZ and LIM domain protein 1 (Fragment) OS=Mus musculus OX=10090 GN=Pdlim1 PE=1 SV=1 0.004 3.391 7 1 2 1 198 21.4 6.38 83214.63281 5234.513184 1 1 regulation of biological process cytoskeleton protein binding "Pf00595, Pf13180" ENSMUSG00000055044.12 19 0 High A0A1Y7VME9 Kinase D-interacting substrate 220 OS=Mus musculus OX=10090 GN=Kidins220 PE=1 SV=1 0.002 4.219 2 2 2 2 1763 195.7 6.71 Met-loss+Acetyl [N-Term] cell organization and biogenesis;regulation of biological process;response to stimulus endosome;membrane enzyme regulator activity;protein binding "Pf00023, Pf07693, Pf12796, Pf13606, Pf13637, Pf13857" 77480 Kidins220 12 0 Low H9KV15 Protein SON OS=Mus musculus OX=10090 GN=Son PE=1 SV=1 0.067 1.244 0 1 2 1 2343 253.9 5.4 58273.30859 13753.79199 1 1 cell organization and biogenesis;metabolic process;regulation of biological process nucleus DNA binding;protein binding;RNA binding 20658 ENSMUSG00000022961.17 Son 16 0 High E9PW37 RAS protein activator-like 2 OS=Mus musculus OX=10090 GN=Rasal2 PE=1 SV=1 0.004 2.722 2 2 2 2 1286 144.5 7.46 10271.26074 47431.78125 1 1 regulation of biological process;response to stimulus cytoplasm enzyme regulator activity;protein binding "Pf00168, Pf00616, Pf12004" 226525 ENSMUSG00000070565.11 Rasal2 1 Interleukin-20 family signaling; Regulation of RAS by GAPs Ras signaling pathway 0 High A0A0B4J1K5 Immunoglobulin lambda variable 3 (Fragment) OS=Mus musculus OX=10090 GN=Iglv3 PE=4 SV=1 0.002 3.944 16 2 2 2 122 13.4 5.76 39303.55469 17366.00195 1 1 response to stimulus "Pf07679, Pf07686" 404743 ENSMUSG00000076939.2 Iglv3; LOC102641542 16 0 High A0A075B5V3 Immunoglobulin heavy variable 1-36 OS=Mus musculus OX=10090 GN=Ighv1-36 PE=4 SV=1 0 5.681 30 2 2 2 116 12.9 8.41 2 2 937286 139677.125 2 1 ENSMUSG00000094051.6 12 0 High Q3UA06 Pachytene checkpoint protein 2 homolog OS=Mus musculus OX=10090 GN=Trip13 PE=1 SV=1 0.002 4.575 6 2 2 2 432 48.3 5.86 3745.84375 3750.251953 1 1 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus nucleus catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00004, Pf00910, Pf02367, Pf05496, Pf06068, Pf07726, Pf07728, Pf13191, Pf13207, Pf13238, Pf13401, Pf13521, Pf13671" 69716 ENSMUSG00000021569.9 Trip13 13 0 High Q9R0P9 Ubiquitin carboxyl-terminal hydrolase isozyme L1 OS=Mus musculus OX=10090 GN=Uchl1 PE=1 SV=1 0.003 3.558 9 1 2 1 223 24.8 5.24 8763.396484 1 cell communication;cell organization and biogenesis;cell proliferation;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;endoplasmic reticulum;membrane catalytic activity;protein binding Pf01088 22223 ENSMUSG00000029223.12 Uchl1 5 UCH proteinases Parkinson's disease 0 Medium Q9WUU7 Cathepsin Z OS=Mus musculus OX=10090 GN=Ctsz PE=1 SV=1 0.013 2.016 4 1 2 1 306 34 6.6 3320.107178 1 metabolic process;regulation of biological process cell surface;endoplasmic reticulum;vacuole catalytic activity Pf00112 64138 ENSMUSG00000016256.10 Ctsz 2 Metabolism of Angiotensinogen to Angiotensins; Lysosome Vesicle Biogenesis; Cargo concentration in the ER; COPII (Coat Protein 2) Mediated Vesicle Transport; Neutrophil degranulation Lysosome; Apoptosis 0 Medium D3Z0I3 "Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (Fragment) OS=Mus musculus OX=10090 GN=Myl2 PE=1 SV=1" 0.031 1.502 12 1 2 1 93 10.6 4.55 Acetyl [N-Term] cell organization and biogenesis;regulation of biological process metal ion binding "Pf00036, Pf13405, Pf13499" ENSMUSG00000013936.12 5 0 High Q91W43 "Glycine dehydrogenase (decarboxylating), mitochondrial OS=Mus musculus OX=10090 GN=Gldc PE=1 SV=1" 0 5.665 2 2 2 2 1025 113.2 7.56 metabolic process;response to stimulus membrane;mitochondrion;nucleus catalytic activity;protein binding "Pf01212, Pf02347" 104174 ENSMUSG00000024827.9 Gldc 19 Glycine degradation "Metabolic pathways; Glycine, serine and threonine metabolism; Carbon metabolism; Glyoxylate and dicarboxylate metabolism" 0 High Q9CRC0 Vitamin K epoxide reductase complex subunit 1 OS=Mus musculus OX=10090 GN=Vkorc1 PE=1 SV=1 0.002 4.008 8 1 2 1 161 17.8 9.14 20705.70508 1 coagulation;metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;membrane catalytic activity Pf07884 27973 ENSMUSG00000096145.2 Vkorc1 7 Metabolism of vitamin K Ubiquinone and other terpenoid-quinone biosynthesis 0 High Q99JZ7 ERBB receptor feedback inhibitor 1 OS=Mus musculus OX=10090 GN=Errfi1 PE=1 SV=1 0.006 2.378 4 1 2 1 461 50 7.72 regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;nucleus protein binding "Pf09027, Pf11555" 74155 ENSMUSG00000028967.10 Errfi1 4 0 High D3Z3S1 Prolactin regulatory element-binding protein OS=Mus musculus OX=10090 GN=Preb PE=1 SV=1 0.002 4.87 9 2 2 2 350 37.9 8.56 3697.352783 14964.33496 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;transport endoplasmic reticulum;membrane;nucleus DNA binding;enzyme regulator activity;protein binding Pf00400 50907 ENSMUSG00000045302.13 Preb 5 0 High G3X972 "Sec24-related gene family, member C (S. cerevisiae) OS=Mus musculus OX=10090 GN=Sec24c PE=1 SV=1" 0.002 3.8 3 2 2 2 1096 118.5 6.84 13661.14355 10930.74512 26942.70117 1 1 1 cell organization and biogenesis;transport cytoplasm;cytosol;membrane metal ion binding;protein binding "Pf00626, Pf04810, Pf04811, Pf04815, Pf08033, Pf09770" 218811 ENSMUSG00000039367.9 Sec24c 14 "Cargo concentration in the ER; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; COPII (Coat Protein 2) Mediated Vesicle Transport; MHC class II antigen presentation" 0 Medium Q9R0L7 A-kinase anchor protein 8-like OS=Mus musculus OX=10090 GN=Akap8l PE=1 SV=1 0.05 1.335 1 1 2 1 642 71.4 5.05 46060.84766 351073.9688 62866.46875 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process chromosome;cytoplasm;nucleus DNA binding;metal ion binding;protein binding;RNA binding Pf04988 54194 Akap8l 17 0 High P52651 Homeobox protein Rhox5 OS=Mus musculus OX=10090 GN=Rhox5 PE=2 SV=1 0.004 2.758 5 2 2 2 210 23 6.25 7500.133301 4662.32373 4704.009766 1 1 1 cell death;cell differentiation;cellular component movement;regulation of biological process cytoplasm;nucleus DNA binding;protein binding 18617 Rhox5 X 0 Medium A0A0R4J138 Arylsulfatase B OS=Mus musculus OX=10090 GN=Arsb PE=1 SV=1 0.018 1.816 2 1 2 1 534 59.7 7.14 7591.53125 5604.381836 15867.6123 1 1 1 cellular component movement;metabolic process;regulation of biological process;response to stimulus cell surface;endoplasmic reticulum;Golgi;mitochondrion;vacuole catalytic activity;metal ion binding Pf00884 11881 ENSMUSG00000042082.6 Arsb 13 CS/DS degradation; Neutrophil degranulation; Glycosphingolipid metabolism; The activation of arylsulfatases Metabolic pathways; Lysosome; Glycosaminoglycan degradation 0 High Q8C0T5 Signal-induced proliferation-associated 1-like protein 1 OS=Mus musculus OX=10090 GN=Sipa1l1 PE=1 SV=2 0.005 3.239 1 1 2 1 1782 196.9 8.13 4985.147461 1 cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane enzyme regulator activity;protein binding "Pf00595, Pf02145, Pf11881" 217692 ENSMUSG00000042700.15 Sipa1l1 12 Rap1 signaling pathway 0 High E9PWK1 Epoxide hydrolase OS=Mus musculus OX=10090 GN=Ephx1 PE=1 SV=1 0.002 5.229 6 2 2 2 441 50.9 8.15 19343.74414 1 metabolic process;response to stimulus endoplasmic reticulum;membrane catalytic activity;protein binding "Pf00561, Pf06441, Pf12697" 13849 ENSMUSG00000038776.13 Ephx1 1 0 High Q9JK92 Heat shock protein beta-8 OS=Mus musculus OX=10090 GN=Hspb8 PE=1 SV=1 0 6.14 8 1 2 1 196 21.5 5.02 cytoplasm;cytosol;nucleus protein binding Pf00011 80888 ENSMUSG00000041548.4 Hspb8 5 HSF1-dependent transactivation 0 Medium P23116 Eukaryotic translation initiation factor 3 subunit A OS=Mus musculus OX=10090 GN=Eif3a PE=1 SV=5 0.02 1.741 1 1 2 1 1344 161.8 6.77 7890.827637 1 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;cytoskeleton;cytosol;membrane;nucleus protein binding;RNA binding Pf01399 13669 ENSMUSG00000024991.7 Eif3a 19 "Formation of a pool of free 40S subunits; L13a-mediated translational silencing of Ceruloplasmin expression; Ribosomal scanning and start codon recognition; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation; GTP hydrolysis and joining of the 60S ribosomal subunit" RNA transport 0 High P83887 Tubulin gamma-1 chain OS=Mus musculus OX=10090 GN=Tubg1 PE=1 SV=1 0.004 2.624 2 1 2 1 451 51.1 6.02 17224.68945 7743.443359 1 1 cell organization and biogenesis;regulation of biological process chromosome;cytoplasm;cytoskeleton;endosome catalytic activity;nucleotide binding;protein binding;structural molecule activity "Pf00091, Pf03953" 103733 ENSMUSG00000035198.9 Tubg1 11 Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes 0 High P61164 Alpha-centractin OS=Mus musculus OX=10090 GN=Actr1a PE=1 SV=1 0.004 2.565 4 1 2 1 376 42.6 6.64 cytoplasm;cytoskeleton nucleotide binding Pf00022 54130 ENSMUSG00000025228.4 Actr1a 19 Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; COPI-mediated anterograde transport; Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes; HSP90 chaperone cycle for steroid hormone receptors (SHR); COPI-independent Golgi-to-ER retrograde traffic; MHC class II antigen presentation 0 High Q91X75 Cyp2a4 protein OS=Mus musculus OX=10090 GN=Cyp2a5 PE=1 SV=1 0.002 5.207 5 2 2 2 494 56.7 9.2 454904.5313 213846 78509.49219 1 1 1 metabolic process;response to stimulus membrane catalytic activity;metal ion binding;protein binding Pf00067 13087; 13086 ENSMUSG00000005547.14 Cyp2a5; Cyp2a4 7 Aflatoxin activation and detoxification; Xenobiotics Retinol metabolism; Metabolic pathways 0 High Q9R182 Angiopoietin-related protein 3 OS=Mus musculus OX=10090 GN=Angptl3 PE=1 SV=1 0 5.487 5 2 2 2 455 52.5 6.65 metabolic process;regulation of biological process;response to stimulus cell surface;endosome;extracellular;Golgi enzyme regulator activity;protein binding Pf00147 30924 ENSMUSG00000028553.12 Angptl3 4 Assembly of active LPL and LIPC lipase complexes 0 Medium O35658 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Mus musculus OX=10090 GN=C1qbp PE=1 SV=1" 0.014 1.922 5 1 2 1 278 31 4.92 17978.09375 5265.867188 1 1 cell death;cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;cytosol;extracellular;membrane;mitochondrion;nucleus;organelle lumen protein binding;RNA binding Pf02330 12261 C1qbp 11 0 High Q9QUK9 TESP4 OS=Mus musculus OX=10090 GN=Try5 PE=1 SV=1 0.004 2.682 8 1 2 1 246 26.3 5.3 1 1 metabolic process catalytic activity;metal ion binding Pf00089 103964 ENSMUSG00000036938.17 Try5 6 "Cobalamin (Cbl, vitamin B12) transport and metabolism; Neutrophil degranulation; Collagen degradation; Antimicrobial peptides; Activation of Matrix Metalloproteinases" Pancreatic secretion; Protein digestion and absorption; Influenza A; Neuroactive ligand-receptor interaction 0 Medium A0A1Y7VJ37 Tetraspanin-13 (Fragment) OS=Mus musculus OX=10090 GN=Tspan13 PE=1 SV=1 0.011 2.111 9 1 2 1 133 14.6 7.81 71891.14844 1 Met-loss [N-Term] regulation of biological process;response to stimulus membrane protein binding Pf00335 66109 Tspan13 12 0 High A0A1L1STE4 Interleukin enhancer-binding factor 3 OS=Mus musculus OX=10090 GN=Ilf3 PE=1 SV=1 0.005 3.168 2 2 2 2 908 97.4 8.92 5766.633301 3457.809082 5675.365723 1 1 1 defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;extracellular;membrane;mitochondrion;nucleus DNA binding;protein binding;RNA binding "Pf00035, Pf07528, Pf14709" 16201 ENSMUSG00000032178.14 Ilf3 9 0 High Q9DCT5 Stromal cell-derived factor 2 OS=Mus musculus OX=10090 GN=Sdf2 PE=1 SV=1 0.005 3.168 14 2 2 2 211 23.1 7.33 273347.0625 138214.3047 1 2 metabolic process;response to stimulus extracellular;membrane catalytic activity Pf02815 20316 Sdf2 11 0 High Q80TS8 Protein sel-1 homolog 3 OS=Mus musculus OX=10090 GN=Sel1l3 PE=2 SV=3 0 7.257 2 1 2 1 1137 128.6 6.64 membrane Pf08238 231238 ENSMUSG00000029189.10 Sel1l3 5 0 Medium Q8C5W0 Calmin OS=Mus musculus OX=10090 GN=Clmn PE=1 SV=2 0.019 1.77 2 1 2 1 1052 117.2 5.03 9331.319336 1 cell organization and biogenesis;regulation of biological process cytoplasm;membrane protein binding "Pf00307, Pf11971" 94040 ENSMUSG00000021097.14 Clmn 12 0 High Q9CQ39 Mediator of RNA polymerase II transcription subunit 21 OS=Mus musculus OX=10090 GN=Med21 PE=1 SV=1 0.002 3.845 22 2 2 2 144 15.6 4.53 8292.359375 44909.38477 1 2 metabolic process;regulation of biological process nucleus catalytic activity;protein binding Pf11221 108098 ENSMUSG00000030291.12 Med21 6 Mus musculus biological processes; Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes 0 Medium A0A0G2JGT5 Eukaryotic translation initiation factor 4E (Fragment) OS=Mus musculus OX=10090 GN=Eif4e PE=1 SV=1 0.029 1.543 6 1 2 1 183 21.4 5.2 4184.922363 1 defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm RNA binding Pf01652 ENSMUSG00000028156.12 3 0 High Q8VE73 Cullin-7 OS=Mus musculus OX=10090 GN=Cul7 PE=1 SV=2 0.003 3.58 2 2 2 2 1689 192.2 6.29 cell death;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;cytoskeleton;Golgi protein binding "Pf00888, Pf11515" 66515 ENSMUSG00000038545.13 Cul7 17 Neddylation Ubiquitin mediated proteolysis 0 High P48678 Prelamin-A/C OS=Mus musculus OX=10090 GN=Lmna PE=1 SV=2 0.002 4.206 2 1 2 1 665 74.2 6.98 1 1 119273.3203 1 cell organization and biogenesis;regulation of biological process;response to stimulus;transport membrane;nucleus protein binding;structural molecule activity "Pf00038, Pf00932, Pf12128" 16905 ENSMUSG00000028063.15 Lmna 3 Clearance of Nuclear Envelope Membranes from Chromatin; Breakdown of the nuclear lamina; Depolymerisation of the Nuclear Lamina; Initiation of Nuclear Envelope Reformation Hypertrophic cardiomyopathy (HCM); Arrhythmogenic right ventricular cardiomyopathy (ARVC); Dilated cardiomyopathy; Apoptosis 0 High Q8BT60 Copine-3 OS=Mus musculus OX=10090 GN=Cpne3 PE=1 SV=2 0 7.717 5 2 2 2 533 59.5 5.78 7841.87793 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;protein binding;RNA binding "Pf00168, Pf07002, Pf10138" 70568 ENSMUSG00000028228.5 Cpne3 4 Neutrophil degranulation; Glycerophospholipid biosynthesis 0 High H3BKG0 Caveolin-1 OS=Mus musculus OX=10090 GN=Cav1 PE=1 SV=1 0.002 4.516 15 1 2 1 93 10.4 6.05 1 2 44519.33252 737376.9531 60016.52734 137248.9648 1 1 1 1 cell differentiation;cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport endoplasmic reticulum;Golgi;membrane enzyme regulator activity;protein binding;structural molecule activity Pf01146 ENSMUSG00000007655.16 6 0 High Q9Z179 SHC SH2 domain-binding protein 1 OS=Mus musculus OX=10090 GN=Shcbp1 PE=1 SV=1 0.003 3.355 3 2 2 2 668 75.9 4.97 regulation of biological process;response to stimulus cytoplasm;cytoskeleton protein binding "Pf05048, Pf12708, Pf13229" 20419 ENSMUSG00000022322.8 Shcbp1 8 0 High A2ARZ3 Fibrous sheath-interacting protein 2 OS=Mus musculus OX=10090 GN=Fsip2 PE=1 SV=3 0.004 2.573 0 2 2 2 6995 784.4 6.51 104510.2852 106273.3242 12310.45117 30013.33398 2 2 1 1 mitochondrion protein binding 241516 ENSMUSG00000075249.12 Fsip2 2 0 High Q3TAA8 Phosphatidylinositol glycan anchor biosynthesis class U protein OS=Mus musculus OX=10090 GN=Pigu PE=1 SV=1 0.002 4.065 6 2 2 2 435 49.9 7.72 metabolic process;regulation of biological process endoplasmic reticulum;membrane catalytic activity Pf06728 228812 ENSMUSG00000038383.16 Pigu 2 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Metabolic pathways 0 High A0A075B5N6 Immunoglobulin kappa variable 8-16 OS=Mus musculus OX=10090 GN=Igkv8-16 PE=4 SV=7 0.005 3.121 16 2 2 1 120 13.4 6.49 1 1 "Pf07679, Pf07686" ENSMUSG00000076591.3 6 0 Medium B2RY56 RNA-binding protein 25 OS=Mus musculus OX=10090 GN=Rbm25 PE=1 SV=2 0.042 1.393 1 1 2 1 838 99.5 6.32 12157.07031 16865.10938 8809.666016 1 1 1 cell death;metabolic process;regulation of biological process cytoplasm;nucleus;spliceosomal complex RNA binding "Pf00076, Pf01480, Pf14259" 67039 ENSMUSG00000010608.15 Rbm25 12 Spliceosome 0 Medium A2A930 Histone-lysine N-methyltransferase PRDM16 OS=Mus musculus OX=10090 GN=Prdm16 PE=1 SV=1 0.02 1.696 1 1 2 1 1257 138.8 6.14 cell differentiation;metabolic process;regulation of biological process cytosol;nucleus DNA binding;metal ion binding;protein binding "Pf00096, Pf00856, Pf02892, Pf13465" 70673 ENSMUSG00000039410.16 Prdm16 4 0 High Q9CQU3 Protein RER1 OS=Mus musculus OX=10090 GN=Rer1 PE=1 SV=1 0.004 2.593 10 1 2 1 196 23 9.51 Met-loss+Acetyl [N-Term] cell organization and biogenesis;regulation of biological process;transport cell surface;Golgi;membrane protein binding Pf03248 67830 ENSMUSG00000029048.3 Rer1 4 0 High F6RJV6 LanC-like protein 2 (Fragment) OS=Mus musculus OX=10090 GN=Lancl2 PE=1 SV=1 0.002 3.909 3 1 2 1 441 49.7 7.14 Pf05147 ENSMUSG00000062190.12 6 0 Medium Q3U1N2 Sterol regulatory element-binding protein 2 OS=Mus musculus OX=10090 GN=Srebf2 PE=1 SV=2 0.049 1.34 1 1 2 1 1130 122.8 8.44 cell communication;metabolic process;regulation of biological process;response to stimulus cytoplasm;endoplasmic reticulum;Golgi;membrane;mitochondrion;nucleus DNA binding;protein binding Pf00010 20788 ENSMUSG00000022463.7 Srebf2 15 Regulation of cholesterol biosynthesis by SREBP (SREBF) 0 High P12849 cAMP-dependent protein kinase type I-beta regulatory subunit OS=Mus musculus OX=10090 GN=Prkar1b PE=1 SV=2 0.005 2.946 5 2 2 2 381 43.2 5.96 cell proliferation;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane enzyme regulator activity;nucleotide binding;protein binding "Pf00027, Pf02197" 19085 ENSMUSG00000025855.13 Prkar1b 5 PKA activation; Signaling by GPCR; PKA activation in glucagon signalling; DARPP-32 events; Hedgehog 'off' state; Vasopressin regulates renal water homeostasis via Aquaporins; Factors involved in megakaryocyte development and platelet production Insulin signaling pathway 0 Low Q3UFQ8 "Capping protein, Arp2/3 and myosin-I linker protein 3 OS=Mus musculus OX=10090 GN=Carmil3 PE=1 SV=2" 0.081 1.102 1 1 2 1 1375 150.3 7.72 578897.1875 666705.875 353899.0313 588324.0625 1 1 1 1 cytoplasm;membrane protein binding 268747 ENSMUSG00000022211.8 Lrrc16b; Carmil3 14 0 Medium A0A1D5RLV7 WD repeat and FYVE domain-containing protein 3 OS=Mus musculus OX=10090 GN=Wdfy3 PE=1 SV=1 0.012 2.051 0 1 2 1 3512 392.6 6.74 14223.75391 11364.79199 1 1 cell communication;metabolic process;response to stimulus cytoplasm;cytosol;membrane;nucleus;vacuole catalytic activity;metal ion binding;protein binding "Pf00400, Pf01363, Pf02138, Pf13385, Pf14844" 72145 ENSMUSG00000043940.15 Wdfy3 5 0 High Q9CZD3 Glycine--tRNA ligase OS=Mus musculus OX=10090 GN=Gars1 PE=1 SV=1 0.004 2.697 3 2 2 2 729 81.8 6.65 metabolic process cytoplasm;cytosol;extracellular;mitochondrion catalytic activity;nucleotide binding;protein binding "Pf00458, Pf00587, Pf03129" 353172 ENSMUSG00000029777.10 Gars 6 Aminoacyl-tRNA biosynthesis 0 Medium Q3TEA8 Heterochromatin protein 1-binding protein 3 OS=Mus musculus OX=10090 GN=Hp1bp3 PE=1 SV=1 0.026 1.58 1 1 2 1 554 60.8 9.7 3883.949707 3371.238525 5383.5625 1 1 1 cell organization and biogenesis;regulation of biological process;response to stimulus chromosome;nucleus DNA binding;protein binding Pf00538 15441 ENSMUSG00000028759.13 Hp1bp3 4 0 High P50462 Cysteine and glycine-rich protein 3 OS=Mus musculus OX=10090 GN=Csrp3 PE=1 SV=1 0.002 3.786 18 2 2 2 194 20.9 8.54 61437.30469 1 cell differentiation;cell organization and biogenesis;cellular homeostasis;development;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;nucleus metal ion binding;protein binding;structural molecule activity Pf00412 13009 ENSMUSG00000030470.15 Csrp3 7 0 High Q91YX5 Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 OS=Mus musculus OX=10090 GN=Lpgat1 PE=1 SV=1 0.003 3.389 6 2 2 2 370 43.1 8.79 98910.80469 1 metabolic process;regulation of biological process cytoplasm;endoplasmic reticulum;membrane catalytic activity Pf01553 226856 ENSMUSG00000026623.16 Lpgat1 1 Acyl chain remodelling of PG Glycerophospholipid metabolism 0 High P97298 Pigment epithelium-derived factor OS=Mus musculus OX=10090 GN=Serpinf1 PE=1 SV=2 0.002 4.968 10 2 2 2 417 46.2 6.98 cellular homeostasis;regulation of biological process;response to stimulus extracellular enzyme regulator activity Pf00079 20317 ENSMUSG00000000753.15 Serpinf1 11 Wnt signaling pathway 0 Medium Q80V94 AP-4 complex subunit epsilon-1 OS=Mus musculus OX=10090 GN=Ap4e1 PE=1 SV=3 0.039 1.433 1 1 2 1 1122 124.8 5.72 1 1 199758.0156 262995.7422 403334.7188 584732.7813 1 1 1 1 transport Golgi;membrane protein binding "Pf01602, Pf14807" 108011 ENSMUSG00000001998.15 Ap4e1 2 Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis Lysosome 0 High Q5SSK3 "Transcription elongation factor, mitochondrial OS=Mus musculus OX=10090 GN=Tefm PE=1 SV=1" 0.005 3.087 10 2 2 2 364 41.8 9.51 6367.185059 1 cell organization and biogenesis;metabolic process;regulation of biological process mitochondrion;organelle lumen enzyme regulator activity;RNA binding Pf12836 68550 ENSMUSG00000046909.9 Tefm 11 0 Medium A0A338P6I2 "DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Mus musculus OX=10090 GN=Polr2h PE=1 SV=1" 0.04 1.408 4 1 2 1 143 16.5 5.05 7162.050781 1 0 High E9PW43 Protein transport protein Sec61 subunit beta OS=Mus musculus OX=10090 GN=Gm10320 PE=3 SV=1 0.007 2.327 10 1 2 1 113 11.8 11.58 transport endoplasmic reticulum;membrane transporter activity Pf03911 ENSMUSG00000092116.1 13 XBP1(S) activates chaperone genes 0 High D4AFX7 DnaJ heat shock protein family (Hsp40) member C13 OS=Mus musculus OX=10090 GN=Dnajc13 PE=1 SV=1 0.002 4.931 2 2 2 2 2248 254.9 6.77 63120.85352 36930.61523 2 2 cell differentiation;cell organization and biogenesis;regulation of biological process;transport cytosol;membrane "Pf00226, Pf14237" 235567 ENSMUSG00000032560.14 Dnajc13 9 Neutrophil degranulation 0 Medium Q9WUL6 Mitogen-activated protein kinase kinase kinase 14 OS=Mus musculus OX=10090 GN=Map3k14 PE=1 SV=1 0.01 2.227 6 2 2 2 942 103 7.5 defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;nucleus catalytic activity;nucleotide binding;protein binding;signal transducer activity "Pf00069, Pf07714" 53859 ENSMUSG00000020941.7 Map3k14 11 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway; Dectin-1 mediated noncanonical NF-kB signaling; NIK-->noncanonical NF-kB signaling; CD28 dependent PI3K/Akt signaling T cell receptor signaling pathway; MAPK signaling pathway; TNF signaling pathway; Epstein-Barr virus infection; HTLV-I infection; Intestinal immune network for IgA production; Osteoclast differentiation; NF-kappa B signaling pathway; Apoptosis 0 High E9PVA8 eIF-2-alpha kinase activator GCN1 OS=Mus musculus OX=10090 GN=Gcn1 PE=1 SV=1 0.004 2.593 1 2 2 2 2671 292.8 7.36 98378.99219 75203.45776 29165.62305 1 2 1 cell communication;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane enzyme regulator activity;protein binding;RNA binding "Pf12074, Pf13646" 231659 ENSMUSG00000041638.18 Gcn1l1 5 0 High Q64012 RNA-binding protein Raly OS=Mus musculus OX=10090 GN=Raly PE=1 SV=3 0.006 2.378 3 1 2 1 312 33.2 8.84 3889.491943 5952.716797 4593.227539 1 1 1 metabolic process;regulation of biological process nucleus;spliceosomal complex RNA binding "Pf00076, Pf13893, Pf14259" 19383 ENSMUSG00000027593.15 Raly 2 0 High Q9DBR7 Protein phosphatase 1 regulatory subunit 12A OS=Mus musculus OX=10090 GN=Ppp1r12a PE=1 SV=2 0.005 2.977 2 2 2 2 1029 114.9 5.49 11414.84375 3006.963135 8767.732422 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus chromosome;cytoplasm;cytoskeleton;cytosol catalytic activity;enzyme regulator activity;protein binding "Pf00023, Pf03961, Pf12796, Pf13606, Pf13637, Pf13857" 17931 ENSMUSG00000019907.10 Ppp1r12a 10 RHO GTPases activate PAKs; Regulation of PLK1 Activity at G2/M Transition; RHO GTPases activate PKNs Oxytocin signaling pathway; Regulation of actin cytoskeleton; Focal adhesion; Platelet activation; Proteoglycans in cancer; cGMP-PKG signaling pathway; cAMP signaling pathway; Vascular smooth muscle contraction 0 High Q9Z2X8 Kelch-like ECH-associated protein 1 OS=Mus musculus OX=10090 GN=Keap1 PE=1 SV=1 0.004 3.466 4 2 2 2 624 69.5 6.44 5563.090332 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;endoplasmic reticulum;nucleus catalytic activity;protein binding "Pf00651, Pf01344, Pf07646, Pf07707, Pf13415, Pf13418, Pf13964" 50868 ENSMUSG00000003308.15 Keap1 9 Neddylation; Ub-specific processing proteases Ubiquitin mediated proteolysis 0 Medium Q8R191 Synaptogyrin-3 OS=Mus musculus OX=10090 GN=Syngr3 PE=1 SV=1 0.011 2.202 5 1 2 1 229 24.5 8.18 regulation of biological process;transport membrane protein binding Pf01284 20974 ENSMUSG00000007021.4 Syngr3 17 0 Medium B2RX70 Cadherin-like and PC-esterase domain-containing 1 OS=Mus musculus OX=10090 GN=Cped1 PE=2 SV=1 0.022 1.654 1 1 2 1 1026 116.8 7.96 endoplasmic reticulum "Pf12733, Pf13839" 214642 ENSMUSG00000062980.15 A430107O13Rik; Cped1 6 0 High Q00724 Retinol-binding protein 4 OS=Mus musculus OX=10090 GN=Rbp4 PE=1 SV=2 0.002 3.951 9 1 2 1 201 23.2 5.99 metabolic process;regulation of biological process;response to stimulus;transport extracellular protein binding;transporter activity "Pf00061, Pf08212" 19662 ENSMUSG00000024990.12 Rbp4 19 The canonical retinoid cycle in rods (twilight vision); Signaling by GPCR; Retinoid metabolism and transport 0 High A0A2I3BQ16 Leucine-rich repeat and calponin homology domain-containing protein 1 OS=Mus musculus OX=10090 GN=Lrch1 PE=1 SV=1 0.002 4.079 4 2 2 2 682 76 6.09 195645.5 132348.3594 1 1 0 Medium P32067 Lupus La protein homolog OS=Mus musculus OX=10090 GN=Ssb PE=1 SV=1 0.039 1.422 2 1 2 1 415 47.7 9.77 metabolic process;transport cytoplasm;nucleus RNA binding "Pf00076, Pf05383, Pf08777, Pf14259" 20823 ENSMUSG00000068882.13 Ssb 2 Systemic lupus erythematosus 0 High P42208 Septin-2 OS=Mus musculus OX=10090 GN=Septin2 PE=1 SV=2 0.005 3.141 7 2 2 2 361 41.5 6.55 46634.61328 11438.36035 19982.41211 2 1 2 cell differentiation;cell division;cell organization and biogenesis;regulation of biological process;response to stimulus cell surface;chromosome;cytoplasm;cytoskeleton;cytosol;membrane;nucleus catalytic activity;enzyme regulator activity;nucleotide binding;protein binding;structural molecule activity "Pf00071, Pf00735, Pf01926" 18000 ENSMUSG00000026276.18; ENSMUSG00000112508.1 Sept2 1 Anchoring of the basal body to the plasma membrane Bacterial invasion of epithelial cells 0 High Q9WTS2 "Alpha-(1,6)-fucosyltransferase OS=Mus musculus OX=10090 GN=Fut8 PE=1 SV=2" 0 7.337 5 2 2 2 575 66.5 7.52 20877.71094 14764.43164 1 1 cellular component movement;metabolic process;regulation of biological process;response to stimulus cytosol;Golgi;membrane catalytic activity;protein binding "Pf00018, Pf02050, Pf14604" 53618 ENSMUSG00000021065.16 Fut8 12 Reactions specific to the complex N-glycan synthesis pathway Metabolic pathways; N-Glycan biosynthesis; Transcriptional misregulation in cancer; Glycosaminoglycan biosynthesis - keratan sulfate 0 High A0A0G2JFN9 Immunoglobulin heavy variable V1-67 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-67 PE=4 SV=1 0.003 3.665 11 1 2 1 117 12.9 8.27 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000095863.2 LOC641089 12 0 High P11438 Lysosome-associated membrane glycoprotein 1 OS=Mus musculus OX=10090 GN=Lamp1 PE=1 SV=2 0.004 2.782 3 1 2 1 406 43.8 8.4 2432.081543 7066.07373 1 1 cell death;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;cytosol;endosome;membrane;vacuole protein binding Pf01299 16783 ENSMUSG00000031447.7 Lamp1 8 Neutrophil degranulation Tuberculosis; Lysosome; Phagosome 0 High Q62351 Transferrin receptor protein 1 OS=Mus musculus OX=10090 GN=Tfrc PE=1 SV=1 0 5.699 3 2 2 2 763 85.7 6.57 cell communication;cell differentiation;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;endosome;extracellular;membrane;mitochondrion;nucleus protein binding;receptor activity;RNA binding;transporter activity "Pf02225, Pf04253, Pf04389" 22042 ENSMUSG00000022797.15 Tfrc 16 Golgi Associated Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis; Transferrin endocytosis and recycling Endocytosis; Phagosome; HIF-1 signaling pathway; Hematopoietic cell lineage 0 High Q9CQ92 Mitochondrial fission 1 protein OS=Mus musculus OX=10090 GN=Fis1 PE=1 SV=1 0.002 4.009 10 1 2 1 152 17 8.53 3704.620117 1 Acetyl [N-Term] cell death;cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport endoplasmic reticulum;membrane;mitochondrion protein binding "Pf14852, Pf14853" 66437 ENSMUSG00000019054.13 Fis1 5 0 High Q99JR5 Tubulointerstitial nephritis antigen-like OS=Mus musculus OX=10090 GN=Tinagl1 PE=1 SV=1 0.002 4.066 3 1 2 1 466 52.6 6.77 1 1 34833.02344 100534.6719 9052.923828 1 1 1 metabolic process;response to stimulus;transport cytoplasm;extracellular;vacuole catalytic activity;protein binding;receptor activity "Pf00112, Pf01033" 94242 ENSMUSG00000028776.14 Tinagl1 4 0 High A0A2R8VHR3 Mannan-binding lectin serine protease 1 OS=Mus musculus OX=10090 GN=Masp1 PE=4 SV=1 0.002 3.804 7 2 2 2 385 44.1 4.68 0 High Q9CWU3 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B OS=Mus musculus OX=10090 GN=Ppp2r2a PE=1 SV=1 0.004 2.567 3 1 2 1 367 42.6 5.36 8379.874023 3645.935303 8298.904297 1 1 1 metabolic process;regulation of biological process;response to stimulus cytosol catalytic activity;enzyme regulator activity;protein binding 71978 Ppp2r2a 14 0 High P24456 Cytochrome P450 2D10 OS=Mus musculus OX=10090 GN=Cyp2d10 PE=1 SV=2 0 6.309 7 2 2 2 504 57.2 6.61 71546.7207 46874.72266 12201.0918 25979.74609 2 1 1 1 metabolic process endoplasmic reticulum;membrane catalytic activity;metal ion binding Pf00067 13101 ENSMUSG00000094806.1 Cyp2d10 15 Xenobiotics Steroid hormone biosynthesis; Serotonergic synapse 0 High G5E8K5 Ankyrin-3 OS=Mus musculus OX=10090 GN=Ank3 PE=1 SV=1 0.004 3.453 1 2 2 1 1961 213.9 6.7 cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;cytoskeleton;endoplasmic reticulum;membrane;vacuole protein binding;structural molecule activity "Pf00023, Pf00531, Pf00791, Pf12796, Pf13606, Pf13637, Pf13857" 11735 ENSMUSG00000069601.14 Ank3 10 COPI-mediated anterograde transport Proteoglycans in cancer 0 High A0A0N4SVS6 Cellular nucleic acid-binding protein OS=Mus musculus OX=10090 GN=Cnbp PE=1 SV=1 0.004 3.502 9 1 2 1 171 18.8 7.71 metabolic process;regulation of biological process cytoplasm;cytosol;endoplasmic reticulum;nucleus DNA binding;metal ion binding;RNA binding 12785 ENSMUSG00000030057.15 Cnbp 6 0 Medium O70310 Glycylpeptide N-tetradecanoyltransferase 1 OS=Mus musculus OX=10090 GN=Nmt1 PE=1 SV=1 0.012 2.066 3 1 2 1 496 56.9 8 21400.8125 15488.90332 1 1 metabolic process cytoplasm;cytosol;membrane catalytic activity "Pf01233, Pf02799" 18107 ENSMUSG00000020936.8 Nmt1 11 "Inactivation, recovery and regulation of the phototransduction cascade; Activation, myristolyation of BID and translocation to mitochondria; Signaling by GPCR" 0 Medium Q9CX53 Gem-associated protein 6 OS=Mus musculus OX=10090 GN=Gemin6 PE=1 SV=2 0.017 1.845 8 1 2 1 166 18.7 5.25 185681.6406 68263.14063 1 1 cell organization and biogenesis;metabolic process cytoplasm;cytosol;nucleus protein binding Pf06372 67242 ENSMUSG00000055760.12 Gemin6 17 snRNP Assembly RNA transport 0 High Q8R3X6 Glypican-6 OS=Mus musculus OX=10090 GN=Gpc6 PE=1 SV=1 0 5.4 4 2 2 1 565 64.3 5.67 2509.193604 1 cellular component movement extracellular;membrane;nucleus protein binding Pf01153 23888 ENSMUSG00000058571.10 Gpc6 14 0 Medium P62715 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform OS=Mus musculus OX=10090 GN=Ppp2cb PE=1 SV=1 0.024 1.602 4 1 2 1 309 35.6 5.43 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus chromosome;cytoplasm;cytoskeleton;cytosol;nucleus catalytic activity;metal ion binding;protein binding Pf00149 19053 ENSMUSG00000009630.10 Ppp2cb 8 "RAF activation; Interleukin-20 family signaling; Cyclin A/B1/B2 associated events during G2/M transition; Resolution of Sister Chromatid Cohesion; Separation of Sister Chromatids; Spry regulation of FGF signaling; Beta-catenin phosphorylation cascade; Activated TLR4 signalling; Signaling by GPCR; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Regulation of TP53 Degradation; CTLA4 inhibitory signaling; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Negative regulation of MAPK pathway; Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal; RHO GTPases Activate Formins; ERKs are inactivated; DARPP-32 events" mRNA surveillance pathway; Chagas disease (American trypanosomiasis); Dopaminergic synapse; Hippo signaling pathway; Oocyte meiosis; Sphingolipid signaling pathway; Long-term depression; TGF-beta signaling pathway; Hepatitis C; PI3K-Akt signaling pathway; AMPK signaling pathway; Tight junction; Adrenergic signaling in cardiomyocytes 0 Medium A0A1W2P7T9 Protein EFR3 homolog B (Fragment) OS=Mus musculus OX=10090 GN=Efr3b PE=1 SV=1 0.012 2.106 1 1 2 1 657 74.2 6.61 36298.875 1 cell organization and biogenesis;metabolic process cytoplasm;membrane 668212 ENSMUSG00000020658.10 Efr3b 12 0 High O88829 "Lactosylceramide alpha-2,3-sialyltransferase OS=Mus musculus OX=10090 GN=St3gal5 PE=2 SV=2" 0 5.436 5 2 2 2 414 47.3 8.51 19785.43994 2 metabolic process Golgi;membrane catalytic activity Pf00777 20454 ENSMUSG00000056091.12 St3gal5 6 Sialic acid metabolism Metabolic pathways; Glycosphingolipid biosynthesis - ganglio series 0 Low O88543 COP9 signalosome complex subunit 3 OS=Mus musculus OX=10090 GN=Cops3 PE=1 SV=3 0.059 1.272 3 1 2 1 423 47.8 6.65 Met-loss+Acetyl [N-Term] metabolic process cytoplasm;cytosol;nucleus protein binding Pf01399 26572 ENSMUSG00000019373.11 Cops3 11 DNA Damage Recognition in GG-NER; Neddylation; Formation of TC-NER Pre-Incision Complex; Cargo recognition for clathrin-mediated endocytosis 0 Medium E0CYC4 Cyclin-dependent kinase 8 (Fragment) OS=Mus musculus OX=10090 GN=Cdk8 PE=1 SV=1 0.019 1.761 4 1 2 1 245 28.5 8.98 6666.713867 14278.76953 13646.21387 1 1 1 metabolic process catalytic activity;nucleotide binding "Pf00069, Pf07714" ENSMUSG00000029635.15 5 0 High Q9CXU0 Mediator of RNA polymerase II transcription subunit 10 OS=Mus musculus OX=10090 GN=Med10 PE=1 SV=1 0.005 3.065 16 2 2 2 135 15.7 6.19 36702.39551 2 metabolic process;regulation of biological process nucleus catalytic activity Pf09748 28077 ENSMUSG00000021598.8 Med10 13 Generic Transcription Pathway; Mus musculus biological processes; Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes 0 High Q8BX02 KN motif and ankyrin repeat domain-containing protein 2 OS=Mus musculus OX=10090 GN=Kank2 PE=1 SV=1 0.004 2.88 3 2 2 2 843 90.2 5.55 7613.648438 1 cell death;metabolic process;regulation of biological process cytoplasm;mitochondrion protein binding "Pf00023, Pf12075, Pf12796, Pf13606, Pf13637, Pf13857" 235041 ENSMUSG00000032194.9 Kank2 9 0 High O88986 "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial OS=Mus musculus OX=10090 GN=Gcat PE=1 SV=2" 0 5.756 3 1 2 1 416 44.9 7.33 metabolic process membrane;mitochondrion;nucleus catalytic activity "Pf00155, Pf00266, Pf00464" 26912 ENSMUSG00000006378.13 Gcat 15 "Glycine, serine and threonine metabolism" 0 High P14206 40S ribosomal protein SA OS=Mus musculus OX=10090 GN=Rpsa PE=1 SV=4 0 5.488 8 2 2 2 295 32.8 4.87 10572.51538 83719.63281 12678.26855 2 1 1 cell differentiation;cell organization and biogenesis;metabolic process;transport cytoplasm;cytosol;membrane;nucleus;ribosome protein binding;receptor activity;RNA binding;structural molecule activity Pf00318 16785; 100045332; 102642689 ENSMUSG00000032518.6 Rpsa; LOC100045332; LOC100505031; LOC102642689 9; 19 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 Medium Q9D8M4 60S ribosomal protein L7-like 1 OS=Mus musculus OX=10090 GN=Rpl7l1 PE=1 SV=1 0.019 1.781 7 1 2 1 246 28.5 10.64 8663.361328 5872.181641 5707.07666 1 1 1 metabolic process ribosome RNA binding;structural molecule activity Pf00327 66229 ENSMUSG00000063888.6 Rpl7l1 17 0 High O08547 Vesicle-trafficking protein SEC22b OS=Mus musculus OX=10090 GN=Sec22b PE=1 SV=3 0.002 3.928 11 2 2 2 215 24.7 8.51 70472.84375 3714.044922 4740.594238 1 1 1 cell organization and biogenesis;regulation of biological process;transport endoplasmic reticulum;Golgi;membrane protein binding "Pf00957, Pf13774" 20333 ENSMUSG00000027879.9 Sec22b 3 Cargo concentration in the ER; ER-Phagosome pathway; COPI-dependent Golgi-to-ER retrograde traffic; COPII (Coat Protein 2) Mediated Vesicle Transport Phagosome; SNARE interactions in vesicular transport; Legionellosis 0 High Q9JK53 Prolargin OS=Mus musculus OX=10090 GN=Prelp PE=1 SV=2 0.005 2.553 3 1 2 1 378 43.3 9.54 21077.89844 21079.22461 36170.69141 1 1 1 cell organization and biogenesis extracellular protein binding;structural molecule activity "Pf01462, Pf12799, Pf13855" 116847 ENSMUSG00000041577.5 Prelp 1 Keratan sulfate degradation; Keratan sulfate biosynthesis 0 Low Q792Z0 "Protease, serine 3 OS=Mus musculus OX=10090 GN=Prss3 PE=1 SV=1" 0.076 1.151 8 1 2 1 246 26.2 5.03 219396.9375 203786.1406 230493.0781 1 1 1 metabolic process catalytic activity Pf00089 22073 ENSMUSG00000071519.6 Prss3 6 "Cobalamin (Cbl, vitamin B12) transport and metabolism; Neutrophil degranulation; Collagen degradation; Antimicrobial peptides; Activation of Matrix Metalloproteinases" 0 Medium P81122 Insulin receptor substrate 2 OS=Mus musculus OX=10090 GN=Irs2 PE=1 SV=2 0.01 2.223 1 1 2 1 1321 136.7 8.69 9132.38916 7400.256348 63199.30078 30642.41211 1 1 1 1 cell proliferation;cellular homeostasis;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane protein binding;signal transducer activity "Pf00169, Pf02174, Pf15413" 384783 ENSMUSG00000038894.7 Irs2 8 "RET signaling; PI3K Cascade; Signal attenuation; Interleukin-7 signaling; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Interleukin-20 family signaling; Signaling by Leptin; IRS activation; Signaling by Leptin; RAF/MAP kinase cascade; SOS-mediated signalling; Mus musculus biological processes; PI3K/AKT activation" FoxO signaling pathway; Type II diabetes mellitus; MicroRNAs in cancer; Regulation of lipolysis in adipocytes; Insulin signaling pathway; Insulin resistance; Longevity regulating pathway; Non-alcoholic fatty liver disease (NAFLD); cGMP-PKG signaling pathway; Adipocytokine signaling pathway; AMPK signaling pathway; Longevity regulating pathway - multiple species 0 Medium P09411 Phosphoglycerate kinase 1 OS=Mus musculus OX=10090 GN=Pgk1 PE=1 SV=4 0.012 2.092 4 1 2 1 417 44.5 7.9 49763.41797 142849.9531 13170.68164 1 1 1 cell differentiation;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane catalytic activity;nucleotide binding Pf00162 18655 ENSMUSG00000062070.12 Pgk1 X Gluconeogenesis; Glycolysis Metabolic pathways; Biosynthesis of amino acids; Glycolysis / Gluconeogenesis; HIF-1 signaling pathway; Carbon metabolism 0 High O55125 Protein NipSnap homolog 1 OS=Mus musculus OX=10090 GN=Nipsnap1 PE=1 SV=1 0.004 2.583 3 1 2 1 284 33.3 9.44 10756.00098 1 membrane;mitochondrion protein binding Pf07978 18082 ENSMUSG00000034285.15 Nipsnap1 11 0 High A0A0G2JGN3 Immunoglobulin heavy variable 1-78 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-78 PE=1 SV=1 0.005 3.153 26 2 2 2 117 13.2 7.99 197233.625 201077.0156 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000096326.2 LOC636126 12 0 High Q810V0 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Mus musculus OX=10090 GN=Mphosph10 PE=1 SV=2 0.004 3.485 3 1 2 1 681 78.7 4.87 metabolic process;regulation of biological process chromosome;nucleus RNA binding Pf04006 67973 ENSMUSG00000030521.11 Mphosph10 7 Major pathway of rRNA processing in the nucleolus and cytosol Ribosome biogenesis in eukaryotes 0 High Q9R099 Transducin beta-like protein 2 OS=Mus musculus OX=10090 GN=Tbl2 PE=1 SV=2 0.002 4.427 3 1 2 1 442 49.6 9.04 cell communication;regulation of biological process;response to stimulus cytoplasm;endoplasmic reticulum protein binding;RNA binding Pf00400 27368 ENSMUSG00000005374.13 Tbl2 5 0 Low Q9Z0M5 Lysosomal acid lipase/cholesteryl ester hydrolase OS=Mus musculus OX=10090 GN=Lipa PE=1 SV=2 0.075 1.179 6 1 1 1 397 45.3 8.07 cell organization and biogenesis;cell proliferation;defense response;metabolic process;response to stimulus vacuole catalytic activity "Pf00561, Pf04083, Pf12695, Pf12697" 16889 ENSMUSG00000024781.15 Lipa 19 LDL clearance Steroid biosynthesis; Lysosome 0 High Q8BTV1 Tumor suppressor candidate 3 OS=Mus musculus OX=10090 GN=Tusc3 PE=1 SV=1 0.005 2.492 3 1 1 1 347 39.5 10.11 metabolic process;transport endoplasmic reticulum;membrane;mitochondrion catalytic activity;transporter activity Pf04756 80286 ENSMUSG00000039530.17 Tusc3 8 Miscellaneous transport and binding events Metabolic pathways; N-Glycan biosynthesis; Protein processing in endoplasmic reticulum 0 High E9Q265 Formylglycine-generating enzyme OS=Mus musculus OX=10090 GN=Sumf1 PE=1 SV=1 0.004 3.419 5 1 1 1 347 37.8 7.42 7835.307129 1 endoplasmic reticulum protein binding Pf03781 ENSMUSG00000030101.15 6 0 High A2AUR3 Phosphotriesterase-related protein (Fragment) OS=Mus musculus OX=10090 GN=Pter PE=1 SV=2 0.005 2.52 8 1 1 1 321 35.8 6.38 metabolic process catalytic activity;metal ion binding "Pf01026, Pf02126" ENSMUSG00000026730.12 2 0 Medium Q62077 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 OS=Mus musculus OX=10090 GN=Plcg1 PE=1 SV=2" 0.05 1.336 2 1 1 1 1302 149.6 5.8 558160 730433.5 122921.7422 1 1 1 cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;membrane catalytic activity;metal ion binding;protein binding;signal transducer activity "Pf00017, Pf00018, Pf00168, Pf00169, Pf00387, Pf00388, Pf03009, Pf07653, Pf09279, Pf14604" 18803 ENSMUSG00000016933.17 Plcg1 2 Role of phospholipids in phagocytosis; Downstream signal transduction; Phospholipase C-mediated cascade; FGFR2; DAP12 signaling; Phospholipase C-mediated cascade: FGFR1; VEGFR2 mediated cell proliferation; FCERI mediated MAPK activation; RET signaling; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; EGFR interacts with phospholipase C-gamma; Frs2-mediated activation; Phospholipase C-mediated cascade; FGFR3; Phospholipase C-mediated cascade; FGFR4; ISG15 antiviral mechanism; Synthesis of IP3 and IP4 in the cytosol; FCERI mediated Ca+2 mobilization; Generation of second messenger molecules ErbB signaling pathway; Leukocyte transendothelial migration; AGE-RAGE signaling pathway in diabetic complications; T cell receptor signaling pathway; Phospholipase D signaling pathway; MicroRNAs in cancer; Ras signaling pathway; VEGF signaling pathway; Epstein-Barr virus infection; Metabolic pathways; Axon guidance; Non-small cell lung cancer; Proteoglycans in cancer; Fc gamma R-mediated phagocytosis; Thyroid hormone signaling pathway; Neurotrophin signaling pathway; Rap1 signaling pathway; HIF-1 signaling pathway; Pathways in cancer; Calcium signaling pathway; NF-kappa B signaling pathway; Inositol phosphate metabolism; Natural killer cell mediated cytotoxicity; Glioma; Fc epsilon RI signaling pathway; EGFR tyrosine kinase inhibitor resistance; Choline metabolism in cancer; Th1 and Th2 cell differentiation; Phosphatidylinositol signaling system; Inflammatory mediator regulation of TRP channels 0 Low Q9CQ73 Plakophilin 2 OS=Mus musculus OX=10090 GN=Pkp2 PE=1 SV=1 0.069 1.234 2 1 1 1 795 88 9.33 59961.96094 42606.40625 1 1 cell communication;cell organization and biogenesis;regulation of biological process membrane protein binding;structural molecule activity Pf00514 67451 ENSMUSG00000041957.15 Pkp2 16 Formation of the cornified envelope Arrhythmogenic right ventricular cardiomyopathy (ARVC) 0 High A0A286YCD7 Adenosine kinase (Fragment) OS=Mus musculus OX=10090 GN=Adk PE=1 SV=1 0.002 3.772 6 1 1 1 205 22.9 7.09 3201.66626 1 0 High F8WH29 Fibrocystin-L OS=Mus musculus OX=10090 GN=Pkhd1l1 PE=1 SV=1 0.006 2.369 1 1 1 1 4247 464.2 6.42 protein binding "Pf01833, Pf07691, Pf10162, Pf13229" ENSMUSG00000038725.12 15 0 Low Q3THK7 GMP synthase [glutamine-hydrolyzing] OS=Mus musculus OX=10090 GN=Gmps PE=1 SV=2 0.075 1.188 1 1 1 1 693 76.7 6.73 metabolic process cytoplasm;cytosol catalytic activity;nucleotide binding "Pf00117, Pf00733, Pf00958, Pf01171, Pf02540, Pf03054, Pf06508, Pf07722" 229363 ENSMUSG00000027823.9 Gmps 3 Purine ribonucleoside monophosphate biosynthesis Metabolic pathways; Purine metabolism; Drug metabolism - other enzymes 0 Medium P63158 High mobility group protein B1 OS=Mus musculus OX=10090 GN=Hmgb1 PE=1 SV=2 0.019 1.766 7 1 1 1 215 24.9 5.74 2867.662842 1 cell differentiation;cell organization and biogenesis;cell proliferation;cellular component movement;cellular homeostasis;defense response;metabolic process;regulation of biological process;response to stimulus;transport cell surface;chromosome;cytoplasm;endosome;extracellular;membrane;nucleus catalytic activity;DNA binding;enzyme regulator activity;protein binding;RNA binding "Pf00505, Pf09011" 15289; 100862258 ENSMUSG00000066551.12 Hmgb1; Gm21596; LOC100862258 5; 2 DEx/H-box helicases activate type I IFN and inflammatory cytokines production ; Activation of DNA fragmentation factor; Activated TLR4 signalling; TAK1 activates NFkB by phosphorylation and activation of IKKs complex; RIP-mediated NFkB activation via ZBP1; Neutrophil degranulation; TRAF6 mediated NF-kB activation; Advanced glycosylation endproduct receptor signaling; Interleukin-1 family signaling; Regulation of TLR by endogenous ligand Base excision repair 0 Medium Q9CQJ2 PIH1 domain-containing protein 1 OS=Mus musculus OX=10090 GN=Pih1d1 PE=1 SV=1 0.023 1.636 4 1 1 1 290 32.2 5.21 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;nucleus DNA binding;protein binding Pf08190 68845 ENSMUSG00000003423.15 Pih1d1 7 0 High A0A0G2JFX7 RNA-binding protein 8A OS=Mus musculus OX=10090 GN=Rbm8a PE=1 SV=1 0.004 2.634 6 1 1 1 171 19.1 4.97 21413.73828 18658.03906 10871.62891 26104.49805 1 1 1 1 metabolic process;transport cytoplasm;nucleus RNA binding "Pf00076, Pf08777, Pf13893, Pf14259" ENSMUSG00000038374.10 3 0 High Q9EPA7 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 OS=Mus musculus OX=10090 GN=Nmnat1 PE=1 SV=2 0.002 3.784 4 1 1 1 285 32.3 9 4550.342285 7570.260254 1 1 metabolic process;response to stimulus nucleus catalytic activity;nucleotide binding;protein binding Pf01467 66454 ENSMUSG00000028992.13 Nmnat1 4 Nicotinate metabolism Metabolic pathways; Nicotinate and nicotinamide metabolism 0 Low Q61647 Hyaluronan synthase 1 OS=Mus musculus OX=10090 GN=Has1 PE=1 SV=1 0.076 1.167 1 1 1 1 583 65.5 9.06 8551.418945 5148.600098 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane catalytic activity "Pf00535, Pf03142, Pf13506, Pf13632, Pf13641" 15116 ENSMUSG00000003665.6 Has1 17 Hyaluronan biosynthesis and export 0 High Q69Z89 Ras-associating and dilute domain-containing protein OS=Mus musculus OX=10090 GN=Radil PE=1 SV=2 0.005 3.059 1 1 1 1 1099 120.3 6.57 1 1 251809.2188 1 cell organization and biogenesis;development;regulation of biological process;response to stimulus protein binding "Pf00498, Pf00595, Pf00788, Pf01843" 231858 ENSMUSG00000029576.17 Radil 5 0 High P63168 "Dynein light chain 1, cytoplasmic OS=Mus musculus OX=10090 GN=Dynll1 PE=1 SV=1" 0.006 2.435 25 1 1 1 89 10.4 7.4 61556.44531 52757.57813 1 1 cell death;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;transport chromosome;cytoplasm;cytoskeleton;cytosol;membrane;mitochondrion;nucleus catalytic activity;enzyme regulator activity;motor activity;protein binding Pf01221 56455 ENSMUSG00000009013.5 Dynll1 5 Activation of BIM and translocation to mitochondria ; Loss of Nlp from mitotic centrosomes; COPI-mediated anterograde transport; Macroautophagy; Recruitment of NuMA to mitotic centrosomes; Intraflagellar transport; Resolution of Sister Chromatid Cohesion; Separation of Sister Chromatids; COPI-independent Golgi-to-ER retrograde traffic; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Recruitment of mitotic centrosome proteins and complexes; Regulation of PLK1 Activity at G2/M Transition; Neutrophil degranulation; HSP90 chaperone cycle for steroid hormone receptors (SHR); Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal; RHO GTPases Activate Formins; MHC class II antigen presentation Vasopressin-regulated water reabsorption 0 Medium P28653 Biglycan OS=Mus musculus OX=10090 GN=Bgn PE=1 SV=1 0.02 1.696 3 1 1 1 369 41.6 7.27 11194.51367 1 metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;extracellular;membrane enzyme regulator activity;protein binding "Pf01462, Pf12799, Pf13855, Pf14580" 12111 ENSMUSG00000031375.17 Bgn X A tetrasaccharide linker sequence is required for GAG synthesis; ECM proteoglycans; CS/DS degradation; Dermatan sulfate biosynthesis; Chondroitin sulfate biosynthesis 0 Medium Q8K2A1 PTB domain-containing engulfment adapter protein 1 OS=Mus musculus OX=10090 GN=Gulp1 PE=1 SV=1 0.012 2.106 6 1 1 1 304 34.4 7.9 cell death;cell organization and biogenesis;regulation of biological process;transport cytoplasm DNA binding;protein binding "Pf00640, Pf04977, Pf07716, Pf08416" 70676 ENSMUSG00000056870.9 Gulp1 1 0 Medium E9Q3I4 Intersectin-1 OS=Mus musculus OX=10090 GN=Itsn1 PE=1 SV=1 0.021 1.727 2 1 1 1 1176 133.1 7.88 25778.65625 32997.80859 11420.5127 141486.8906 1 1 1 1 metabolic process;regulation of biological process;response to stimulus;transport catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00018, Pf02463, Pf02841, Pf03357, Pf03938, Pf04111, Pf04156, Pf04502, Pf05262, Pf05557, Pf06818, Pf07653, Pf07888, Pf09726, Pf09731, Pf09756, Pf09798, Pf10037, Pf10174, Pf10186, Pf11559, Pf11600, Pf12072, Pf12128, Pf12763, Pf13868, Pf14604, Pf14915, Pf15346, Pf15558, Pf15619" ENSMUSG00000022957.19 16 0 High Q5FW60 Major urinary protein 20 OS=Mus musculus OX=10090 GN=Mup20 PE=1 SV=1 0.005 2.509 8 1 1 1 181 20.9 4.89 44602.93359 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytosol;extracellular;nucleus catalytic activity;protein binding;receptor activity;signal transducer activity;transporter activity Pf00061 381530 ENSMUSG00000078672.2 Mup20; LOC100505376 4 0 Low Q99L85 Elongator complex protein 5 OS=Mus musculus OX=10090 GN=Elp5 PE=2 SV=1 0.058 1.275 3 1 1 1 300 33.5 5.49 7514.335449 1 metabolic process;regulation of biological process cytoplasm;cytosol;nucleus Pf10483 54351 ENSMUSG00000018565.17 Elp5 11 0 Medium P46096 Synaptotagmin-1 OS=Mus musculus OX=10090 GN=Syt1 PE=1 SV=1 0.012 2.102 3 1 1 1 421 47.4 8.53 cell differentiation;cell organization and biogenesis;regulation of biological process;response to stimulus;transport cytoplasm;Golgi;membrane metal ion binding;protein binding Pf00168 20979 ENSMUSG00000035864.14 Syt1 10 "Acetylcholine Neurotransmitter Release Cycle; Cargo recognition for clathrin-mediated endocytosis; Norepinephrine Neurotransmitter Release Cycle; GABA synthesis, release, reuptake and degradation; Glutamate Neurotransmitter Release Cycle" Synaptic vesicle cycle 0 Low P50516 V-type proton ATPase catalytic subunit A OS=Mus musculus OX=10090 GN=Atp6v1a PE=1 SV=2 0.06 1.259 2 1 1 1 617 68.3 5.58 14168.57617 22370.33789 1 1 cellular homeostasis;metabolic process;response to stimulus;transport cytosol;membrane;mitochondrion catalytic activity;nucleotide binding;transporter activity "Pf00006, Pf00306, Pf02874" 11964 ENSMUSG00000052459.13 Atp6v1a 16 "Ion channel transport; ROS, RNS production in phagocytes; Transferrin endocytosis and recycling; Insulin receptor recycling" mTOR signaling pathway; Rheumatoid arthritis; Metabolic pathways; Phagosome; Oxidative phosphorylation; Synaptic vesicle cycle; Collecting duct acid secretion 0 Medium Q9JMD0 BUB3-interacting and GLEBS motif-containing protein ZNF207 OS=Mus musculus OX=10090 GN=Znf207 PE=1 SV=1 0.023 1.638 3 1 1 1 495 52.8 9.1 37336.87109 22503.92773 7750.819336 36053.76172 1 1 1 1 cell division;cell organization and biogenesis;regulation of biological process chromosome;cytoplasm;cytoskeleton;nucleus metal ion binding;protein binding;RNA binding 22680 ENSMUSG00000017421.18 Zfp207 11 0 High Q4VAA7 Sorting nexin-33 OS=Mus musculus OX=10090 GN=Snx33 PE=1 SV=1 0.002 4.022 2 1 1 1 574 65.3 6.79 63101.52734 1 cell division;cell organization and biogenesis;regulation of biological process;transport cytoplasm;cytosol;membrane protein binding "Pf00018, Pf00787, Pf07653, Pf10456, Pf14604" 235406 ENSMUSG00000032733.6 Snx33 9 0 Medium E9QP59 Inner nuclear membrane protein Man1 OS=Mus musculus OX=10090 GN=Lemd3 PE=1 SV=1 0.017 1.825 1 1 1 1 918 100.1 7.55 cell differentiation;cell organization and biogenesis;cellular component movement;regulation of biological process membrane;nucleus DNA binding "Pf03020, Pf09402" 380664 ENSMUSG00000048661.14 Lemd3 10 0 Medium Q5SU71 E3 ubiquitin/ISG15 ligase TRIM25 OS=Mus musculus OX=10090 GN=Trim25 PE=1 SV=1 0.017 1.836 2 1 1 1 626 70.7 8.12 defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol catalytic activity;metal ion binding;protein binding;RNA binding "Pf00097, Pf00622, Pf13445, Pf13639, Pf13765, Pf13920, Pf13923, Pf14634, Pf15227" 217069 ENSMUSG00000000275.16 Trim25 11 0 Low P63154 Crooked neck-like protein 1 OS=Mus musculus OX=10090 GN=Crnkl1 PE=1 SV=1 0.06 1.258 2 1 1 1 690 83.4 6.93 66295.21875 23976.19141 40206.94141 1 1 1 cell organization and biogenesis;metabolic process nucleus;spliceosomal complex protein binding;RNA binding "Pf02184, Pf05843" 66877 ENSMUSG00000001767.5 Crnkl1 2 mRNA Splicing - Major Pathway Spliceosome 0 High Q5I2A0 Serine protease inhibitor A3G OS=Mus musculus OX=10090 GN=Serpina3g PE=1 SV=2 0.002 4.499 3 1 1 1 440 49 6.46 15487.00195 1 cell death;regulation of biological process;response to stimulus cytoplasm;nucleus enzyme regulator activity Pf00079 20715 Serpina3g 12 0 Medium Q6R891 Neurabin-2 OS=Mus musculus OX=10090 GN=Ppp1r9b PE=1 SV=1 0.011 2.178 1 1 1 1 817 89.5 4.92 cell differentiation;cell organization and biogenesis;cellular component movement;development;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;membrane;nucleus catalytic activity;enzyme regulator activity;protein binding;transporter activity "Pf00595, Pf01496, Pf04111, Pf04156, Pf05557, Pf07106, Pf07888" 217124 ENSMUSG00000038976.12 Ppp1r9b 11 0 High P63325 40S ribosomal protein S10 OS=Mus musculus OX=10090 GN=Rps10 PE=1 SV=1 0.004 2.797 9 1 1 1 165 18.9 10.15 6676.168457 1 cell organization and biogenesis cytoplasm;cytosol;membrane;nucleus;ribosome RNA binding;structural molecule activity Pf03501 67097 ENSMUSG00000052146.15 Rps10 17 Ribosome 0 Medium Q4FE56 Probable ubiquitin carboxyl-terminal hydrolase FAF-X OS=Mus musculus OX=10090 GN=Usp9x PE=1 SV=1 0.044 1.368 1 1 1 1 2554 290 5.83 cell division;cell growth;cellular component movement;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane catalytic activity;protein binding "Pf00443, Pf13423" 22284 ENSMUSG00000031010.17 Usp9x X Downregulation of SMAD2/3:SMAD4 transcriptional activity; Ub-specific processing proteases; Synthesis of active ubiquitin: roles of E1 and E2 enzymes 0 High B1AUE5 Peroxisome biogenesis factor 10 OS=Mus musculus OX=10090 GN=Pex10 PE=2 SV=1 0.005 2.96 3 1 1 1 324 37.1 9.94 cell organization and biogenesis;transport membrane metal ion binding;protein binding "Pf00097, Pf04757, Pf12678, Pf13639, Pf13920, Pf13923, Pf14634, Pf15227" 668173 ENSMUSG00000029047.13 Pex10 4 E3 ubiquitin ligases ubiquitinate target proteins Peroxisome 0 Medium Q8K2A6 Lipase member M OS=Mus musculus OX=10090 GN=Lipm PE=2 SV=1 0.013 1.98 2 1 1 1 422 48.2 8.53 metabolic process extracellular catalytic activity "Pf00561, Pf04083, Pf12695, Pf12697" 78753 ENSMUSG00000056078.5 Lipm 19 Formation of the cornified envelope 0 High Q9CYA0 Protein disulfide isomerase Creld2 OS=Mus musculus OX=10090 GN=Creld2 PE=1 SV=1 0.005 2.906 5 1 1 1 350 38.2 4.58 endoplasmic reticulum;extracellular;Golgi metal ion binding "Pf03302, Pf11938" 76737 ENSMUSG00000023272.3 Creld2 15 0 High P97364 "Selenide, water dikinase 2 OS=Mus musculus OX=10090 GN=Sephs2 PE=1 SV=3" 0.003 3.325 7 1 1 1 452 47.8 6.06 Met-loss+Acetyl [N-Term] metabolic process catalytic activity;nucleotide binding "Pf00586, Pf02769" 20768 ENSMUSG00000049091.6 Sephs2 7 Selenocysteine synthesis Metabolic pathways; Selenocompound metabolism 0 High A0A075B5Y3 Immunoglobulin heavy variable 1-80 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-80 PE=1 SV=1 0.002 5.237 13 1 1 1 117 12.8 8.78 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000094075.1 LOC677445 12 0 Medium A0A0R4J0Q5 Lamin-B2 OS=Mus musculus OX=10090 GN=Lmnb2 PE=1 SV=1 0.024 1.622 2 1 1 1 615 69 5.55 membrane;nucleus structural molecule activity "Pf00038, Pf00932, Pf04156" 16907 ENSMUSG00000062075.13 Lmnb2 10 0 Medium Q9CQT1 Methylthioribose-1-phosphate isomerase OS=Mus musculus OX=10090 GN=Mri1 PE=1 SV=1 0.011 2.173 3 1 1 1 369 39.4 5.91 8626.551758 1 metabolic process cytoplasm;cytosol;nucleus catalytic activity;protein binding Pf01008 67873 ENSMUSG00000004996.9 Mri1 8 Methionine salvage pathway Metabolic pathways; Cysteine and methionine metabolism 0 Medium Q91YN9 BAG family molecular chaperone regulator 2 OS=Mus musculus OX=10090 GN=Bag2 PE=1 SV=1 0.013 2 5 1 1 1 210 23.5 6.42 metabolic process;regulation of biological process enzyme regulator activity;nucleotide binding;protein binding Pf02179 213539 ENSMUSG00000042215.8 Bag2 1 Protein processing in endoplasmic reticulum 0 Low P59470 DNA-directed RNA polymerase III subunit RPC2 OS=Mus musculus OX=10090 GN=Polr3b PE=1 SV=2 0.068 1.242 1 1 1 1 1133 127.6 8.5 defense response;metabolic process;regulation of biological process;response to stimulus nucleus catalytic activity;DNA binding;metal ion binding "Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf04566, Pf04567" 70428 ENSMUSG00000034453.8 Polr3b 10 RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA polymerase; Epstein-Barr virus infection; Metabolic pathways; Purine metabolism; Pyrimidine metabolism; Cytosolic DNA-sensing pathway 0 High D3Z2U5 Inactive serine/threonine-protein kinase VRK3 (Fragment) OS=Mus musculus OX=10090 GN=Vrk3 PE=1 SV=9 0.004 2.875 14 1 1 1 175 19.4 9.19 regulation of biological process nucleus protein binding "Pf10571, Pf12773, Pf13240, Pf13248" ENSMUSG00000002205.16 7 0 Medium A0A0A6YX72 Immunoglobulin heavy variable V15-2 (Fragment) OS=Mus musculus OX=10090 GN=Ighv15-2 PE=4 SV=1 0.024 1.617 14 1 1 1 118 13.1 5.15 11076.1875 14633.46973 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000076688.2 12 0 Low E9PYF9 Cytosolic carboxypeptidase 1 OS=Mus musculus OX=10090 GN=Agtpbp1 PE=4 SV=1 0.06 1.262 17 1 1 1 42 4.8 9.88 ENSMUSG00000021557.14 13 0 High A0A075B5K9 Immunoglobulin kappa variable 12-98 OS=Mus musculus OX=10090 GN=Igkv12-98 PE=4 SV=7 0 6.22 17 1 1 1 114 12.3 7.83 141784.4844 1 Pf07686 ENSMUSG00000076526.6 6 0 Medium A0A087WP87 E3 ubiquitin-protein ligase RING2 (Fragment) OS=Mus musculus OX=10090 GN=Rnf2 PE=1 SV=1 0.035 1.448 3 1 1 1 211 23.2 8.16 ENSMUSG00000026484.13 1 0 Medium A0A498WGD8 Thioredoxin-like protein 1 OS=Mus musculus OX=10090 GN=Txnl1 PE=1 SV=1 0.022 1.657 8 1 1 1 292 32.7 5.07 10915.45508 1 Met-loss [N-Term] 0 High P61967 AP-1 complex subunit sigma-1A OS=Mus musculus OX=10090 GN=Ap1s1 PE=1 SV=1 0.002 3.835 10 1 1 1 158 18.7 5.73 response to stimulus;transport cytosol;Golgi;membrane protein binding;transporter activity Pf01217 11769 ENSMUSG00000004849.14 Ap1s1 5 MHC class II antigen presentation; Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis Lysosome 0 Medium Q3V0K9 Plastin-1 OS=Mus musculus OX=10090 GN=Pls1 PE=1 SV=1 0.03 1.526 2 1 1 1 630 70.4 5.38 12484.92773 71621.25781 1 1 cell organization and biogenesis;regulation of biological process;transport cytoplasm;cytoskeleton metal ion binding;protein binding "Pf00036, Pf00307, Pf13405, Pf13499, Pf13833" 102502 ENSMUSG00000049493.13 Pls1 9 0 Low Q3V009 Transmembrane emp24 domain-containing protein 1 OS=Mus musculus OX=10090 GN=Tmed1 PE=1 SV=1 0.076 1.15 6 1 1 1 227 25.2 4.5 6664.177246 1 transport endoplasmic reticulum;Golgi;membrane Pf01105 17083 ENSMUSG00000032180.11 Tmed1 9 0 Medium Q6IQX7 Chondroitin sulfate synthase 2 OS=Mus musculus OX=10090 GN=Chpf PE=1 SV=1 0.025 1.597 1 1 1 1 774 85.5 6.84 metabolic process cytoplasm;cytosol;Golgi;membrane;mitochondrion;organelle lumen catalytic activity;metal ion binding;protein binding "Pf02434, Pf05679" 74241 ENSMUSG00000032997.16 Chpf 1 Chondroitin sulfate biosynthesis Metabolic pathways; Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate 0 High Q4VAC9 Pleckstrin homology domain-containing family G member 3 OS=Mus musculus OX=10090 GN=Plekhg3 PE=1 SV=2 0.006 2.431 2 1 1 1 1341 148.4 5.68 regulation of biological process "Pf00169, Pf00621" 263406 ENSMUSG00000052609.9 Plekhg3 12 0 Low Q70FJ1 A-kinase anchor protein 9 OS=Mus musculus OX=10090 GN=Akap9 PE=1 SV=2 0.076 1.161 0 1 1 1 3797 435.9 5.03 3936.7771 1 cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;Golgi protein binding;structural molecule activity "Pf05852, Pf10495, Pf12128, Pf13166" 100986 Akap9 5 0 Low Q63918 Caveolae-associated protein 2 OS=Mus musculus OX=10090 GN=Cavin2 PE=1 SV=3 0.073 1.19 2 1 1 1 418 46.7 5.21 79623.25781 1 cell organization and biogenesis;regulation of biological process cytoplasm;cytosol;membrane protein binding Pf15237 20324 ENSMUSG00000045954.7 Sdpr; Cavin2 1 0 High Q924Z4 Ceramide synthase 2 OS=Mus musculus OX=10090 GN=Cers2 PE=1 SV=1 0.005 2.482 2 1 1 1 380 45 8.75 metabolic process;regulation of biological process endoplasmic reticulum;membrane;nucleus catalytic activity;DNA binding Pf03798 76893 ENSMUSG00000015714.11 Cers2; Lass2 3 Sphingolipid de novo biosynthesis Metabolic pathways; Sphingolipid signaling pathway; Sphingolipid metabolism 0 Medium B1AQH6 Mediator of RNA polymerase II transcription subunit 1 OS=Mus musculus OX=10090 GN=Med1 PE=3 SV=1 0.047 1.353 3 1 1 1 629 70.1 7.72 6465.060547 11109.74609 1 1 cell differentiation;cell organization and biogenesis;cell proliferation;development;metabolic process;regulation of biological process;response to stimulus;transport chromosome;membrane;nucleus catalytic activity;DNA binding;protein binding;receptor activity Pf10744 19014 ENSMUSG00000018160.15 Med1 11 0 Low Q9Z126 Platelet factor 4 OS=Mus musculus OX=10090 GN=Pf4 PE=1 SV=1 0.053 1.315 11 1 1 1 105 11.2 9.29 cell organization and biogenesis;cellular component movement;defense response;regulation of biological process;response to stimulus cytoplasm;extracellular protein binding Pf00048 56744 ENSMUSG00000029373.7 Pf4 5 G alpha (i) signalling events; Cell surface interactions at the vascular wall; Chemokine receptors bind chemokines; Common Pathway of Fibrin Clot Formation; Platelet degranulation Chemokine signaling pathway; Cytokine-cytokine receptor interaction 0 Medium G3UWB7 Transmembrane protein 255B OS=Mus musculus OX=10090 GN=Tmem255b PE=4 SV=1 0.04 1.416 7 1 1 1 328 35 7.12 membrane Pf14967 272465 ENSMUSG00000038457.17 Fam70b; Tmem255b 8 0 Medium Q8R155 "Lymphocyte antigen 6 complex, locus G2 OS=Mus musculus OX=10090 GN=Ly6g2 PE=1 SV=1" 0.016 1.861 20 1 1 1 124 13.4 4.59 Pf00021 223631 ENSMUSG00000047728.12 BC025446 15 0 Low Q9Z0G2 SRSF protein kinase 3 OS=Mus musculus OX=10090 GN=Srpk3 PE=1 SV=1 0.06 1.266 7 1 1 1 565 62.3 7.21 cell differentiation;cell organization and biogenesis;development;metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus catalytic activity;nucleotide binding "Pf00069, Pf07714" 56504 ENSMUSG00000002007.5 Srpk3 X 0 Medium Q8BR37 E3 ubiquitin-protein ligase NHLRC1 OS=Mus musculus OX=10090 GN=Nhlrc1 PE=2 SV=1 0.021 1.731 4 1 1 1 401 42.7 7.31 35167.5 1 metabolic process;regulation of biological process endoplasmic reticulum;nucleus catalytic activity;metal ion binding;protein binding 105193 ENSMUSG00000044231.2 Nhlrc1 13 Glycogen synthesis Ubiquitin mediated proteolysis 0 Medium P60229 Eukaryotic translation initiation factor 3 subunit E OS=Mus musculus OX=10090 GN=Eif3e PE=1 SV=1 0.018 1.819 2 1 1 1 445 52.2 6.04 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;cytosol;membrane;nucleus protein binding;RNA binding "Pf01399, Pf09440" 16341 ENSMUSG00000022336.2 Eif3e 15 "Formation of a pool of free 40S subunits; L13a-mediated translational silencing of Ceruloplasmin expression; Ribosomal scanning and start codon recognition; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation; GTP hydrolysis and joining of the 60S ribosomal subunit" Hepatitis C; RNA transport 0 Medium P70208 Plexin-A3 OS=Mus musculus OX=10090 GN=Plxna3 PE=1 SV=2 0.049 1.339 0 1 1 1 1872 207.8 7.09 cell growth;cellular component movement;regulation of biological process;response to stimulus membrane;nucleus protein binding;receptor activity;signal transducer activity "Pf01403, Pf01437, Pf01833, Pf08337" 18846 ENSMUSG00000031398.13 Plxna3 X CRMPs in Sema3A signaling; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion; Sema3A PAK dependent Axon repulsion Axon guidance 0 Low Q8BHD0 Ras-related protein Rab-39A OS=Mus musculus OX=10090 GN=Rab39a PE=1 SV=1 0.053 1.32 5 1 1 1 217 25 7.06 13841.24023 6871.401367 1 1 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport Golgi;membrane;vacuole catalytic activity;nucleotide binding;protein binding "Pf00025, Pf00071, Pf08477" 270160 ENSMUSG00000055069.3 Rab39 9 RAB GEFs exchange GTP for GDP on RABs; Intra-Golgi traffic 0 High Q924Y0 Gamma-butyrobetaine dioxygenase OS=Mus musculus OX=10090 GN=Bbox1 PE=1 SV=1 0.007 2.329 3 1 1 1 387 44.7 6.92 metabolic process cytoplasm;mitochondrion catalytic activity;metal ion binding;protein binding "Pf02668, Pf06155" 170442 ENSMUSG00000041660.8 Bbox1 2 Carnitine synthesis Lysine degradation 0 Low A0A0R4J187 X-ray repair cross-complementing protein 6 OS=Mus musculus OX=10090 GN=Xrcc6 PE=1 SV=1 0.079 1.132 2 1 1 1 608 69.4 6.52 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus chromosome;cytoplasm;membrane;nucleus catalytic activity;DNA binding;nucleotide binding;protein binding;RNA binding "Pf02037, Pf02735, Pf03730, Pf03731" 14375 ENSMUSG00000022471.13 Xrcc6 15 Neutrophil degranulation; Nonhomologous End-Joining (NHEJ) Non-homologous end-joining 0 Medium Q9JHP7 Protein O-glucosyltransferase 2 OS=Mus musculus OX=10090 GN=Poglut2 PE=1 SV=1 0.011 2.196 4 1 1 1 502 57.9 7.9 10710.83887 6846.214844 11114.03906 30420.29297 1 1 1 1 metabolic process endoplasmic reticulum;organelle lumen catalytic activity;protein binding "Pf00630, Pf05686, Pf13524" 72050 ENSMUSG00000026047.13 Kdelc1 1 0 Low E9PU96 Nucleolar pre-ribosomal-associated protein 1 OS=Mus musculus OX=10090 GN=Urb1 PE=1 SV=1 0.079 1.131 2 1 1 1 2277 254.7 6.96 nucleus RNA binding Pf11707 207932 ENSMUSG00000039929.14 Urb1 16 0 Medium D3Z2B1 Low-density lipoprotein receptor-related protein 11 OS=Mus musculus OX=10090 GN=Lrp11 PE=1 SV=1 0.017 1.829 3 1 1 1 438 47.4 8.38 6987.369629 1 protein binding "Pf00057, Pf07502" ENSMUSG00000019796.12 10 0 Medium Q80YE7 Death-associated protein kinase 1 OS=Mus musculus OX=10090 GN=Dapk1 PE=1 SV=3 0.02 1.697 1 1 1 1 1442 161.3 6.89 cell death;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane catalytic activity;nucleotide binding;protein binding "Pf00023, Pf00069, Pf00531, Pf07714, Pf12796, Pf13606, Pf13637, Pf13857" 69635 Dapk1 13 Pathways in cancer; Bladder cancer 0 High Q91WT8 RNA-binding protein 47 OS=Mus musculus OX=10090 GN=Rbm47 PE=1 SV=1 0.005 3.168 2 1 1 1 590 64 8.19 cell differentiation;metabolic process nucleus protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 245945 ENSMUSG00000070780.11 Rbm47 5 0 High Q9Z0H3 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 OS=Mus musculus OX=10090 GN=Smarcb1 PE=1 SV=1 0.006 2.377 3 1 1 1 385 44.1 6.23 7087.496582 1 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus chromosome;nucleus DNA binding;protein binding Pf04855 20587 ENSMUSG00000000902.13 Smarcb1 10 RMTs methylate histone arginines; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 0 Medium Q8BG19 Protein O-mannosyl-transferase TMTC4 OS=Mus musculus OX=10090 GN=Tmtc4 PE=2 SV=1 0.016 1.863 2 1 1 1 741 82.9 8.69 4676.005371 4978.635254 2146.124023 1 1 1 membrane protein binding "Pf00515, Pf07719, Pf08409, Pf13181, Pf13414, Pf13424, Pf13431, Pf13432, Pf14559" 70551 ENSMUSG00000041594.17 Tmtc4 14 0 Low Q8VC97 Beta-ureidopropionase OS=Mus musculus OX=10090 GN=Upb1 PE=1 SV=1 0.06 1.267 5 1 1 1 393 43.9 6.79 4237.137207 1 metabolic process cytoplasm catalytic activity;metal ion binding Pf00795 103149 ENSMUSG00000033427.14 Upb1 10 Pyrimidine catabolism Metabolic pathways; beta-Alanine metabolism; Pyrimidine metabolism; Drug metabolism - other enzymes; Pantothenate and CoA biosynthesis 0 Medium P58269 Zinc finger protein DPF3 OS=Mus musculus OX=10090 GN=Dpf3 PE=1 SV=2 0.047 1.352 3 1 1 1 378 43 6.42 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process nucleus metal ion binding;protein binding "Pf00628, Pf14051" 70127 ENSMUSG00000021221.15 Dpf3 12 0 Low P0DM40 Fer-1-like protein 5 OS=Mus musculus OX=10090 GN=Fer1l5 PE=1 SV=1 0.056 1.295 1 1 1 1 2038 235.7 7.83 membrane protein binding "Pf00168, Pf08150, Pf08151" 100534273 ENSMUSG00000037432.15 Fer1l5 1 0 High A0A0N4SUU0 "Pleckstrin homology domain-containing, family A member 5 (Fragment) OS=Mus musculus OX=10090 GN=Plekha5 PE=1 SV=1" 0.004 2.781 1 1 1 1 956 108.5 8.84 2866.777588 1 metabolic process cytosol;membrane "Pf00169, Pf04111, Pf15413" ENSMUSG00000030231.11 6 0 Medium Q91W92 Cdc42 effector protein 1 OS=Mus musculus OX=10090 GN=Cdc42ep1 PE=1 SV=1 0.022 1.649 5 1 1 1 409 43.1 7.21 cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane enzyme regulator activity;protein binding Pf00786 104445 Cdc42ep1 15 0 Low Q4U2R1 E3 ubiquitin-protein ligase HERC2 OS=Mus musculus OX=10090 GN=Herc2 PE=1 SV=3 0.073 1.208 0 1 1 1 4836 527.1 6.27 metabolic process;response to stimulus cytoplasm;cytoskeleton;membrane;nucleus catalytic activity;metal ion binding;protein binding "Pf00173, Pf00415, Pf00569, Pf00632, Pf03256, Pf06701, Pf11515, Pf13540" 15204 ENSMUSG00000030451.15 Herc2 7 G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ); SUMOylation of DNA damage response and repair proteins; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Ubiquitin mediated proteolysis 0 High P70245 "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase OS=Mus musculus OX=10090 GN=Ebp PE=1 SV=3" 0.003 3.341 6 1 1 1 230 26.2 7.56 138637.4219 987156.75 1 1 Met-loss+Acetyl [N-Term] metabolic process endoplasmic reticulum;membrane;nucleus catalytic activity Pf05241 13595 ENSMUSG00000031168.14 Ebp X Cholesterol biosynthesis via desmosterol; Cholesterol biosynthesis via lathosterol Steroid biosynthesis; Metabolic pathways 0 Medium Q9DAA6 Exosome complex component CSL4 OS=Mus musculus OX=10090 GN=Exosc1 PE=1 SV=1 0.031 1.489 6 1 1 1 195 21.4 8.24 metabolic process cytoplasm;nucleus protein binding;RNA binding "Pf10447, Pf14382" 66583 ENSMUSG00000034321.13 Exosc1 19 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease; Major pathway of rRNA processing in the nucleolus and cytosol; KSRP (KHSRP) binds and destabilizes mRNA RNA degradation 0 High A0A087WQZ9 Lymphocyte antigen 96 OS=Mus musculus OX=10090 GN=Ly96 PE=1 SV=1 0.003 3.382 11 1 1 1 142 16.2 6.77 defense response;regulation of biological process;response to stimulus extracellular protein binding;receptor activity;signal transducer activity Pf02221 17087 ENSMUSG00000025779.10 Ly96 1 0 Medium Q8CC47 N-acetylgalactosamine-6-sulfatase OS=Mus musculus OX=10090 GN=Galns PE=1 SV=1 0.042 1.39 2 1 1 1 440 48.5 6.52 4693.330566 1 metabolic process vacuole catalytic activity;metal ion binding "Pf00884, Pf01663, Pf02995, Pf14707" 50917 ENSMUSG00000015027.11 Galns 8 0 Medium P61079 Ubiquitin-conjugating enzyme E2 D3 OS=Mus musculus OX=10090 GN=Ube2d3 PE=1 SV=1 0.021 1.665 16 1 1 1 147 16.7 7.8 cell death;metabolic process;response to stimulus endosome;membrane catalytic activity;nucleotide binding;protein binding "Pf00179, Pf14461" 66105 ENSMUSG00000078578.9 Ube2d3 3 E3 ubiquitin ligases ubiquitinate target proteins; Activated TLR4 signalling; Downregulation of SMAD2/3:SMAD4 transcriptional activity; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Signaling by BMP; Neddylation; IKK complex recruitment mediated by RIP1 Ubiquitin mediated proteolysis; Protein processing in endoplasmic reticulum 0 Medium Q9QYK4 Heparan-sulfate 6-O-sulfotransferase 3 OS=Mus musculus OX=10090 GN=Hs6st3 PE=1 SV=2 0.021 1.717 1 1 1 1 470 55 7.01 metabolic process membrane catalytic activity Pf03567 50787 ENSMUSG00000053465.5 Hs6st3 14 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 0 Medium S4R2T8 Disks large homolog 1 OS=Mus musculus OX=10090 GN=Dlg1 PE=1 SV=1 0.011 2.182 3 1 1 1 558 60.7 6 protein binding "Pf00595, Pf09058, Pf10600, Pf10608, Pf13180" ENSMUSG00000022770.16 16 0 Medium Q8BRJ4 Protein phosphatase 1 regulatory subunit 3E OS=Mus musculus OX=10090 GN=Ppp1r3e PE=1 SV=2 0.024 1.616 5 1 1 1 279 30.6 11.15 23625.51758 13173.54395 6448.532227 1 1 1 metabolic process;regulation of biological process catalytic activity;protein binding Pf03370 105651 Ppp1r3e 14 0 Low F7CRG8 Serine/threonine-protein kinase MARK2 (Fragment) OS=Mus musculus OX=10090 GN=Mark2 PE=1 SV=1 0.059 1.276 12 1 1 1 174 18.6 11.52 33954.97656 133874.375 1 1 cell organization and biogenesis;metabolic process catalytic activity ENSMUSG00000024969.15 19 0 Low E9PZ67 Calsequestrin (Fragment) OS=Mus musculus OX=10090 GN=Casq2 PE=1 SV=1 0.052 1.329 4 1 1 1 312 36.4 4.58 9423.833984 1 metal ion binding "Pf01216, Pf13848" ENSMUSG00000027861.13 3 0 Medium P60766 Cell division control protein 42 homolog OS=Mus musculus OX=10090 GN=Cdc42 PE=1 SV=2 0.012 2.071 5 1 1 1 191 21.2 6.55 cell communication;cell differentiation;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;membrane;vacuole catalytic activity;nucleotide binding;protein binding "Pf00025, Pf00071, Pf08477" 12540 ENSMUSG00000006699.17 Cdc42 4 RHO GTPases activate KTN1; EGFR downregulation; VEGFA-VEGFR2 Pathway; CD28 dependent Vav1 pathway; MAPK6/MAPK4 signaling; Regulation of actin dynamics for phagocytic cup formation; RHO GTPases activate PAKs; RHO GTPases activate IQGAPs; Rho GTPase cycle; Mitotic Prometaphase; RHO GTPases Activate Formins; RHO GTPases Activate WASPs and WAVEs; DCC mediated attractive signaling; Factors involved in megakaryocyte development and platelet production; EPHB-mediated forward signaling; CDO in myogenesis Leukocyte transendothelial migration; AGE-RAGE signaling pathway in diabetic complications; Endocytosis; T cell receptor signaling pathway; Regulation of actin cytoskeleton; MAPK signaling pathway; Ras signaling pathway; VEGF signaling pathway; Focal adhesion; Chemokine signaling pathway; Axon guidance; Adherens junction; Non-alcoholic fatty liver disease (NAFLD); Proteoglycans in cancer; Salmonella infection; Fc gamma R-mediated phagocytosis; Neurotrophin signaling pathway; Rap1 signaling pathway; Pathways in cancer; Pancreatic cancer; Renal cell carcinoma; GnRH signaling pathway; Tight junction; Viral carcinogenesis; Bacterial invasion of epithelial cells 0 Medium F8WHP8 "ATP synthase, H+-transporting, mitochondrial F0 complex, subunit F2 OS=Mus musculus OX=10090 GN=Atp5j2 PE=1 SV=1" 0.019 1.775 16 1 1 1 76 9 9.88 membrane;mitochondrion Pf10206 ENSMUSG00000038690.15 5 0 Medium O70479 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 OS=Mus musculus OX=10090 GN=Tnfaip1 PE=2 SV=1 0.018 1.811 2 1 1 1 316 36.1 7.84 cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus cytoplasm;endosome;nucleus catalytic activity;protein binding Pf02214 21927 ENSMUSG00000017615.12 Tnfaip1 11 0 Medium E9Q8K5 Titin OS=Mus musculus OX=10090 GN=Ttn PE=1 SV=1 0.018 1.809 0 1 1 1 33467 3713.7 6.37 23071012 10710664 12526267 1 1 1 metabolic process catalytic activity;nucleotide binding;protein binding "Pf00041, Pf00047, Pf00069, Pf07679, Pf07686, Pf07714, Pf09042, Pf13895, Pf13927" ENSMUSG00000051747.14 2 0 Medium E9Q3T7 Adenylosuccinate lyase OS=Mus musculus OX=10090 GN=Adsl PE=1 SV=1 0.011 2.125 3 1 1 1 425 48.3 7.78 8264.097656 3070.666016 4485.471191 1 1 1 metabolic process mitochondrion catalytic activity Pf00206 ENSMUSG00000022407.9 15 0 Medium P61924 Coatomer subunit zeta-1 OS=Mus musculus OX=10090 GN=Copz1 PE=1 SV=1 0.022 1.643 8 1 1 1 177 20.2 4.81 Acetyl [N-Term] transport cytoplasm;Golgi;membrane Pf01217 56447 ENSMUSG00000060992.8 Copz1 15 COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic 0 Medium Q62418 Drebrin-like protein OS=Mus musculus OX=10090 GN=Dbnl PE=1 SV=2 0.035 1.462 5 1 1 1 436 48.7 4.92 cell organization and biogenesis;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;endosome;Golgi;membrane protein binding "Pf00018, Pf00241, Pf07653, Pf14604" 13169 ENSMUSG00000020476.14 Dbnl 11 Neutrophil degranulation; Caspase-mediated cleavage of cytoskeletal proteins; Neurexins and neuroligins 0 High Q61830 Macrophage mannose receptor 1 OS=Mus musculus OX=10090 GN=Mrc1 PE=1 SV=2 0.007 2.303 1 1 1 1 1456 164.9 6.83 regulation of biological process;response to stimulus;transport cell surface;endosome;membrane receptor activity;signal transducer activity "Pf00040, Pf00059, Pf00652" 17533 ENSMUSG00000026712.3 Mrc1 2 Tuberculosis; Phagosome 0 Low A0A0R4J049 Protein arginine N-methyltransferase 5 OS=Mus musculus OX=10090 GN=Prmt5 PE=1 SV=1 0.08 1.117 1 1 1 1 637 72.7 6.34 2470.397949 1 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;cytosol;Golgi;nucleus catalytic activity;DNA binding;nucleotide binding;protein binding "Pf02475, Pf05185, Pf13659" 27374 ENSMUSG00000023110.12 Prmt5 14 RMTs methylate histone arginines; snRNP Assembly; Regulation of TP53 Activity through Methylation RNA transport 0 Low Q3TZG8 Nucleolar protein 4-like OS=Mus musculus OX=10090 GN=Nol4l PE=1 SV=1 0.06 1.258 4 1 1 1 435 47.2 5.08 1 1 129032.6953 74062.40625 1 1 cytosol 329540 ENSMUSG00000061411.12 8430427H17Rik; Nol4l 2 0 Medium P35456 Urokinase plasminogen activator surface receptor OS=Mus musculus OX=10090 GN=Plaur PE=1 SV=1 0.019 1.772 5 1 1 1 327 35.4 6.83 cell differentiation;metabolic process;regulation of biological process;response to stimulus cell surface;extracellular;membrane catalytic activity;protein binding;receptor activity;signal transducer activity Pf00021 18793 ENSMUSG00000046223.10 Plaur 7 Dissolution of Fibrin Clot; Neutrophil degranulation; Attachment of GPI anchor to uPAR Complement and coagulation cascades; Proteoglycans in cancer 0 High Q920V1 "UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 OS=Mus musculus OX=10090 GN=B3galnt1 PE=2 SV=2" 0.003 3.316 3 1 1 1 331 39.3 8.02 metabolic process Golgi;membrane catalytic activity Pf01762 26879 ENSMUSG00000043300.2 B3galnt1 3 Glycosphingolipid metabolism Glycosphingolipid biosynthesis - globo and isoglobo series; Metabolic pathways; Glycosphingolipid biosynthesis - lacto and neolacto series 0 Low Q8CF66 Ragulator complex protein LAMTOR4 OS=Mus musculus OX=10090 GN=Lamtor4 PE=1 SV=2 0.076 1.17 11 1 1 1 99 10.7 5.76 9345.65332 57802.22656 1 1 Met-loss [N-Term] cell organization and biogenesis;regulation of biological process;response to stimulus vacuole protein binding;structural molecule activity 66096 ENSMUSG00000050552.8 0910001L09Rik; Lamtor4 5 Regulation of PTEN gene transcription; mTORC1-mediated signalling; TP53 Regulates Metabolic Genes; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK mTOR signaling pathway 0 Low Q810B6 Rabankyrin-5 OS=Mus musculus OX=10090 GN=Ankfy1 PE=1 SV=2 0.083 1.052 3 1 1 1 1169 128.6 5.91 cell organization and biogenesis;regulation of biological process;transport cytoplasm;cytosol;endosome;membrane metal ion binding;protein binding "Pf00023, Pf00651, Pf01363, Pf07707, Pf12796, Pf13606, Pf13637, Pf13857" 11736 ENSMUSG00000020790.14 Ankfy1 11 0 High Q8VCS6 Mediator of RNA polymerase II transcription subunit 9 OS=Mus musculus OX=10090 GN=Med9 PE=2 SV=1 0.005 3.254 16 1 1 1 142 15.7 7.44 15128.48047 43509.97266 1 1 metabolic process;regulation of biological process nucleus protein binding Pf07544 192191 ENSMUSG00000061650.6 Med9 11 Mus musculus biological processes; Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes 0 Medium Q61495 Desmoglein-1-alpha OS=Mus musculus OX=10090 GN=Dsg1a PE=2 SV=2 0.013 2.029 1 1 1 1 1057 114.5 4.89 membrane metal ion binding;protein binding "Pf00028, Pf01049" 13510 ENSMUSG00000069441.3 Dsg1a 18 Formation of the cornified envelope; Neutrophil degranulation; Apoptotic cleavage of cell adhesion proteins Staphylococcus aureus infection 0 Medium A0A0R4IZY9 tRNA-dihydrouridine(47) synthase [NAD(P)(+)] OS=Mus musculus OX=10090 GN=Dus3l PE=1 SV=1 0.015 1.868 3 1 1 1 637 71.1 7.9 metabolic process catalytic activity;metal ion binding;nucleotide binding;RNA binding Pf01207 224907 ENSMUSG00000007603.8 Dus3l 17 0 High Q9CXW2 "28S ribosomal protein S22, mitochondrial OS=Mus musculus OX=10090 GN=Mrps22 PE=1 SV=1" 0.005 3.09 3 1 1 1 359 41.2 8.56 11668.79395 60278.69922 12434.09668 19199.47461 1 1 1 1 mitochondrion;ribosome structural molecule activity Pf10245 64655 ENSMUSG00000032459.9 Mrps22 9 Mitochondrial translation termination; Mitochondrial translation elongation 0 Medium Q9D823 60S ribosomal protein L37 OS=Mus musculus OX=10090 GN=Rpl37 PE=3 SV=3 0.013 2.001 10 1 1 1 97 11.1 11.74 Met-loss [N-Term] metabolic process ribosome metal ion binding;protein binding;RNA binding;structural molecule activity Pf01907 100502825; 67281 ENSMUSG00000041841.7 Gm13826; Rpl37rt; Rpl37 5; 15 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 Medium Q61024 Asparagine synthetase [glutamine-hydrolyzing] OS=Mus musculus OX=10090 GN=Asns PE=1 SV=3 0.012 2.091 2 1 1 1 561 64.2 6.58 2526.575684 7063.975586 1 1 cell communication;metabolic process;regulation of biological process;response to stimulus cytosol catalytic activity;nucleotide binding;protein binding "Pf00310, Pf00733, Pf12481, Pf13522, Pf13537" 27053 ENSMUSG00000029752.12 Asns 6 Amino acid synthesis and interconversion (transamination) "Metabolic pathways; Alanine, aspartate and glutamate metabolism" 0 Medium Q9CYN9 Renin receptor OS=Mus musculus OX=10090 GN=Atp6ap2 PE=1 SV=2 0.018 1.782 2 1 1 1 350 39.1 5.54 5249.984863 1 metabolic process;regulation of biological process membrane protein binding;receptor activity Pf07850 70495 ENSMUSG00000031007.2 Atp6ap2 X Metabolism of Angiotensinogen to Angiotensins; Neutrophil degranulation Renin-angiotensin system 0 Medium F8WJ94 Killer cell lectin-like receptor 7 OS=Mus musculus OX=10090 GN=Klra7 PE=4 SV=1 0.042 1.385 3 1 1 1 280 32.5 8.12 1 1 139647.2656 69941.17188 1 1 membrane "Pf00059, Pf08391" 16638 ENSMUSG00000067599.13 Klra7 6 Graft-versus-host disease; Natural killer cell mediated cytotoxicity 0 Medium Q8BG13 RNA-binding protein 3 OS=Mus musculus OX=10090 GN=Rbm3 PE=1 SV=1 0.021 1.706 12 1 1 1 154 16.8 8.38 metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus RNA binding "Pf00076, Pf13893, Pf14259" 19652 ENSMUSG00000031167.16 Rbm3 X 0 Medium Q03141 MAP/microtubule affinity-regulating kinase 3 OS=Mus musculus OX=10090 GN=Mark3 PE=1 SV=2 0.011 2.142 2 1 1 1 753 84.3 9.51 cell organization and biogenesis;metabolic process;regulation of biological process membrane catalytic activity;nucleotide binding;protein binding "Pf00069, Pf00627, Pf02149, Pf07714, Pf14531" 17169 Mark3 12 MAP2K and MAPK activation; Negative regulation of MAPK pathway; RAF activation; Interleukin-20 family signaling 0 Medium Q921C3 Bromodomain and WD repeat-containing protein 1 OS=Mus musculus OX=10090 GN=Brwd1 PE=1 SV=2 0.02 1.668 0 1 1 1 2304 259.1 8.4 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;cytosol;nucleus protein binding "Pf00400, Pf00439" 93871 ENSMUSG00000022914.15 Brwd1 16 Chromatin modifying enzymes; Interleukin-7 signaling 0 Low Q8CIL4 Uncharacterized protein C1orf131 homolog OS=Mus musculus OX=10090 PE=1 SV=1 0.077 1.158 4 1 1 1 281 31.3 9.85 chromosome RNA binding Pf15375 66523 ENSMUSG00000031984.8 2810004N23Rik 8 0 Medium A0A0U1RPA0 Pleckstrin homology domain-containing family A member 7 (Fragment) OS=Mus musculus OX=10090 GN=Plekha7 PE=1 SV=1 0.012 2.033 1 1 1 1 1212 137.2 9.28 3546.777832 1 metabolic process "Pf00169, Pf02463, Pf04111, Pf07798, Pf14992, Pf15409, Pf15413" ENSMUSG00000045659.18 7 0 High Q8VCY6 U3 small nucleolar RNA-associated protein 6 homolog OS=Mus musculus OX=10090 GN=Utp6 PE=2 SV=1 0.004 2.771 3 1 1 1 597 70.4 7.71 metabolic process nucleus protein binding;RNA binding Pf08640 216987 ENSMUSG00000035575.11 Utp6 11 Major pathway of rRNA processing in the nucleolus and cytosol Ribosome biogenesis in eukaryotes 0 Low Q9Z0P4 Paralemmin-1 OS=Mus musculus OX=10090 GN=Palm PE=1 SV=1 0.083 1.054 4 1 1 1 383 41.6 4.84 1 1 258513.8594 124680.5703 263294.75 1 1 1 cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus protein binding Pf03285 18483 ENSMUSG00000035863.14 Palm 10 0 High G3UXL2 Phosphoribosyl pyrophosphate synthetase 1-like 3 OS=Mus musculus OX=10090 GN=Prps1l3 PE=3 SV=1 0.004 2.609 7 1 1 1 318 34.8 6.98 16604.76367 5052215 2532849.25 3476728.5 1 1 1 1 metabolic process catalytic activity;metal ion binding "Pf00156, Pf13793, Pf14572" 328099 ENSMUSG00000079104.4 Prps1l3 12 Metabolic pathways; Biosynthesis of amino acids; Purine metabolism; Pentose phosphate pathway; Carbon metabolism 0 Medium Q3UG20 Inactive histone-lysine N-methyltransferase 2E OS=Mus musculus OX=10090 GN=Kmt2e PE=1 SV=2 0.014 1.925 1 1 1 1 1868 204.4 7.42 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport nucleus catalytic activity;metal ion binding;protein binding;transporter activity "Pf00430, Pf00628, Pf00856, Pf09770" 69188 ENSMUSG00000029004.15 Kmt2e; Mll5 5 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; PKMTs methylate histone lysines Lysine degradation 0 Medium D3Z3F1 Pre-mRNA 3'-end-processing factor FIP1 (Fragment) OS=Mus musculus OX=10090 GN=Fip1l1 PE=1 SV=2 0.031 1.492 3 1 1 1 434 46.4 4.74 9695.404297 2677.727295 1 1 Pf05182 ENSMUSG00000029227.15 5 0 High Q3UEL5 Urocanate hydratase OS=Mus musculus OX=10090 GN=Uroc1 PE=1 SV=1 0.002 4.077 2 1 1 1 710 78.4 7.27 11805.38965 10261.92188 6952.39209 1 1 1 metabolic process cytosol catalytic activity Pf01175 243537 ENSMUSG00000034456.15 Uroc1 6 Histidine metabolism; Metabolic pathways 0 High Q91VZ6 Stromal membrane-associated protein 1 OS=Mus musculus OX=10090 GN=Smap1 PE=1 SV=1 0.007 2.35 3 1 1 1 440 47.6 8.51 cell organization and biogenesis;regulation of biological process cytoplasm;membrane enzyme regulator activity;metal ion binding;protein binding Pf01412 98366 ENSMUSG00000026155.13 Smap1 1 Endocytosis 0 Medium Q99LH2 Phosphatidylserine synthase 1 OS=Mus musculus OX=10090 GN=Ptdss1 PE=1 SV=1 0.011 2.217 2 1 1 1 473 55.6 8.28 metabolic process endoplasmic reticulum;membrane catalytic activity Pf03034 19210 ENSMUSG00000021518.3 Ptdss1 13 Synthesis of PS Metabolic pathways; Glycerophospholipid metabolism 0 Low A0A087WNL5 E3 ubiquitin-protein ligase MSL2 OS=Mus musculus OX=10090 GN=Msl2 PE=1 SV=1 0.076 1.158 13 1 1 1 100 10.9 8.48 154732.8438 17480.49023 24688.06055 1 1 1 ENSMUSG00000066415.4 9 0 Low Q9ESJ0 Exportin-4 OS=Mus musculus OX=10090 GN=Xpo4 PE=1 SV=2 0.08 1.116 2 1 1 1 1151 129.9 5.12 242584.9063 186715.2813 1 1 Met-loss+Acetyl [N-Term] regulation of biological process;transport cytoplasm;cytosol;nucleus protein binding;transporter activity 57258 ENSMUSG00000021952.15 Xpo4 14 0 High Q61985 Endoplasmic reticulum membrane sensor NFE2L1 OS=Mus musculus OX=10090 GN=Nfe2l1 PE=1 SV=2 0.006 2.465 2 1 1 1 741 81.5 4.7 18808 10964.84961 1 1 cell differentiation;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;endoplasmic reticulum;membrane;nucleus DNA binding;protein binding "Pf00170, Pf03131, Pf07716" 18023 ENSMUSG00000038615.17 Nfe2l1 11 0 High Q80X81 Acetyl-Coenzyme A acetyltransferase 3 OS=Mus musculus OX=10090 GN=Acat3 PE=1 SV=1 0.007 2.242 3 1 1 1 397 41.4 7.94 metabolic process cytoplasm;cytosol;mitochondrion;nucleus catalytic activity "Pf00108, Pf00109, Pf02803, Pf08541" 224530 ENSMUSG00000062480.11 Acat3 17 Cholesterol biosynthesis 0 Medium Q8VE22 "28S ribosomal protein S23, mitochondrial OS=Mus musculus OX=10090 GN=Mrps23 PE=1 SV=1" 0.017 1.825 6 1 1 1 177 20.3 8.59 7660.030762 8941.147461 13709.82617 1 1 1 metabolic process cytoskeleton;membrane;mitochondrion;ribosome RNA binding;structural molecule activity "Pf10484, Pf13741" 64656 ENSMUSG00000023723.17; ENSMUSG00000098375.6 Mrps23 11; CHR_MG3829_PATCH Mitochondrial translation termination; Mitochondrial translation elongation 0 Low Q5SV80 Unconventional myosin-XIX OS=Mus musculus OX=10090 GN=Myo19 PE=1 SV=1 0.072 1.216 3 1 1 1 963 108 7.9 cellular component movement;regulation of biological process cytoplasm;cytoskeleton;membrane;mitochondrion catalytic activity;motor activity;nucleotide binding;protein binding "Pf00063, Pf00612" 66196 ENSMUSG00000020527.14 Myo19 11 0 Medium A0A0R4J2B6 Retinoblastoma-binding protein 5 OS=Mus musculus OX=10090 GN=Rbbp5 PE=1 SV=1 0.04 1.417 4 1 1 1 537 59 5.1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus nucleus catalytic activity;DNA binding;protein binding Pf00400 213464 ENSMUSG00000026439.14 Rbbp5 1 0 Medium Q5F2F2 Protein ABHD15 OS=Mus musculus OX=10090 GN=Abhd15 PE=1 SV=1 0.011 2.158 3 1 1 1 459 51.1 7.99 metabolic process extracellular;membrane catalytic activity 67477 ENSMUSG00000000686.11 Abhd15 11 0 Medium A0A2R8VHT2 Cytochrome P450 2D9 (Fragment) OS=Mus musculus OX=10090 GN=Cyp2d9 PE=1 SV=1 0.017 1.846 5 1 1 1 208 23.7 6.55 7861.575195 1 0 Medium Q5DTJ9 Myopalladin OS=Mus musculus OX=10090 GN=Mypn PE=1 SV=2 0.022 1.64 2 1 1 1 1315 144 6.54 cell organization and biogenesis;regulation of biological process cytoplasm;nucleus protein binding "Pf00047, Pf07679, Pf13895, Pf13927" 68802 ENSMUSG00000020067.8 Mypn 10 0 Medium O35375 Neuropilin-2 OS=Mus musculus OX=10090 GN=Nrp2 PE=1 SV=2 0.042 1.387 2 1 1 1 931 104.6 5.24 cell differentiation;cell growth;cellular component movement;development;regulation of biological process;response to stimulus membrane catalytic activity;metal ion binding;protein binding;receptor activity;signal transducer activity "Pf00431, Pf00629, Pf00754, Pf11980" 18187 ENSMUSG00000025969.15 Nrp2 1 Neurophilin interactions with VEGF and VEGFR 0 High P47856 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Mus musculus OX=10090 GN=Gfpt1 PE=1 SV=3 0.005 2.935 3 1 1 1 697 78.5 6.84 cell organization and biogenesis;metabolic process;regulation of biological process catalytic activity "Pf00310, Pf01380, Pf13230, Pf13522, Pf13537, Pf13580" 14583 ENSMUSG00000029992.14 Gfpt1 6 Synthesis of UDP-N-acetyl-glucosamine "Metabolic pathways; Insulin resistance; Amino sugar and nucleotide sugar metabolism; Alanine, aspartate and glutamate metabolism" 0 Medium Q7TNL7 Dual specificity protein phosphatase OS=Mus musculus OX=10090 GN=Dusp9 PE=1 SV=1 0.02 1.698 2 1 1 1 452 48.6 5.16 5583.31543 1 metabolic process;regulation of biological process cytoplasm catalytic activity "Pf00102, Pf00782, Pf03162, Pf14566" 75590 ENSMUSG00000031383.8 Dusp9 X RAF-independent MAPK1/3 activation; Negative regulation of MAPK pathway; Interleukin-20 family signaling MAPK signaling pathway; Signaling pathways regulating pluripotency of stem cells 0 Medium O55222 Integrin-linked protein kinase OS=Mus musculus OX=10090 GN=Ilk PE=1 SV=2 0.039 1.425 2 1 1 1 452 51.3 8.07 15444.62207 14585.16406 12106.01953 1 1 1 cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane catalytic activity;nucleotide binding;protein binding;signal transducer activity "Pf00023, Pf00069, Pf07714, Pf12796, Pf13606, Pf13637, Pf13857" 16202 ENSMUSG00000030890.16 Ilk 7 Localization of the PINCH-ILK-PARVIN complex to focal adhesions PPAR signaling pathway; Focal adhesion; Endometrial cancer; Axon guidance; Bacterial invasion of epithelial cells 0 Medium E0CYI4 All-trans-retinol dehydrogenase [NAD(+)] ADH4 (Fragment) OS=Mus musculus OX=10090 GN=Adh4 PE=1 SV=8 0.036 1.441 9 1 1 1 216 23.2 8.25 metabolic process catalytic activity;metal ion binding Pf08240 ENSMUSG00000037797.14 3 0 Medium Q9Z1N5 Spliceosome RNA helicase Ddx39b OS=Mus musculus OX=10090 GN=Ddx39b PE=1 SV=1 0.022 1.647 2 1 1 1 428 49 5.67 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;nucleus;spliceosomal complex catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00270, Pf00271, Pf14617" 53817 ENSMUSG00000019432.15 Ddx39b 17 mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA surveillance pathway; Spliceosome; Influenza A; RNA transport 0 Low Q8VEL0 Motile sperm domain-containing protein 1 OS=Mus musculus OX=10090 GN=Mospd1 PE=1 SV=1 0.079 1.134 14 1 1 1 213 24.1 7.74 cell differentiation;regulation of biological process cytoplasm;endoplasmic reticulum;Golgi;membrane;nucleus Pf00635 70380 ENSMUSG00000023074.11 Mospd1 X 0 High P16301 Phosphatidylcholine-sterol acyltransferase OS=Mus musculus OX=10090 GN=Lcat PE=1 SV=2 0.004 2.568 3 1 1 1 438 49.7 6.43 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport extracellular catalytic activity;protein binding "Pf02450, Pf06821" 16816 ENSMUSG00000035237.7 Lcat 8 HDL remodeling Glycerophospholipid metabolism 0 Medium A2AMD0 Predicted gene 12666 (Fragment) OS=Mus musculus OX=10090 GN=Gm12666 PE=1 SV=1 0.02 1.677 4 1 1 1 254 28.4 9.72 RNA binding "Pf00076, Pf13893, Pf14259" 68280 ENSMUSG00000066107.6 Gm12666 4 0 Medium Q05117 Tartrate-resistant acid phosphatase type 5 OS=Mus musculus OX=10090 GN=Acp5 PE=1 SV=2 0.03 1.516 6 1 1 1 327 36.8 8.9 20152.76367 1 defense response;metabolic process;regulation of biological process;response to stimulus vacuole catalytic activity;metal ion binding Pf00149 11433 ENSMUSG00000001348.15 Acp5 9 Vitamin B2 (riboflavin) metabolism Rheumatoid arthritis; Lysosome; Osteoclast differentiation 0 Low A2AI05 NADPH-dependent diflavin oxidoreductase 1 OS=Mus musculus OX=10090 GN=Ndor1 PE=2 SV=1 0.069 1.233 2 1 1 1 598 67.1 6.61 cell death;metabolic process;response to stimulus cytoplasm;cytoskeleton;cytosol;nucleus catalytic activity;nucleotide binding "Pf00175, Pf00258, Pf00667" 78797 ENSMUSG00000006471.18 Ndor1 2 0 High O09159 Lysosomal alpha-mannosidase OS=Mus musculus OX=10090 GN=Man2b1 PE=1 SV=4 0.002 4.235 1 1 1 1 1013 114.6 8.13 metabolic process;response to stimulus vacuole catalytic activity;metal ion binding "Pf01074, Pf07748, Pf09261" 17159 ENSMUSG00000005142.10 Man2b1 8 Lysosomal oligosaccharide catabolism; Neutrophil degranulation Lysosome; Other glycan degradation 0 Medium Q99P87 Resistin OS=Mus musculus OX=10090 GN=Retn PE=1 SV=1 0.021 1.726 11 1 1 1 114 12.5 7.75 1 1 cell differentiation;regulation of biological process;response to stimulus extracellular;nucleus protein binding Pf06954 57264 ENSMUSG00000012705.16 Retn 8 Neutrophil degranulation 0 High B2RRI5 Leucine-rich repeats and immunoglobulin-like domains protein 2 OS=Mus musculus OX=10090 GN=Lrig2 PE=1 SV=1 0.005 2.911 2 1 1 1 1047 117 5.58 regulation of biological process cytoplasm;membrane protein binding "Pf00047, Pf07679, Pf12799, Pf13306, Pf13855, Pf13895, Pf13927, Pf14580" 269473 ENSMUSG00000032913.13 Lrig2 3 0 Medium A0A0B4J1H5 "T cell receptor beta, variable 20 (Fragment) OS=Mus musculus OX=10090 GN=Trbv20 PE=4 SV=1" 0.044 1.369 29 1 1 1 111 12.4 8.76 Pf07679 ENSMUSG00000076476.1 6 0 High A0A0G2JDZ8 Nexilin (Fragment) OS=Mus musculus OX=10090 GN=Nexn PE=1 SV=1 0.004 2.767 6 1 1 1 272 32.7 5.38 2733.892822 1 ENSMUSG00000039103.12 3 0 Low P12710 "Fatty acid-binding protein, liver OS=Mus musculus OX=10090 GN=Fabp1 PE=1 SV=2" 0.055 1.302 9 1 1 1 127 14.2 8.56 regulation of biological process;response to stimulus;transport cytoplasm;cytosol;nucleus;organelle lumen antioxidant activity;catalytic activity;transporter activity "Pf00061, Pf14651" 14080 ENSMUSG00000054422.7 Fabp1 6 Triglyceride catabolism; Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) PPAR signaling pathway; Fat digestion and absorption 0 High Q2TPA8 Hydroxysteroid dehydrogenase-like protein 2 OS=Mus musculus OX=10090 GN=Hsdl2 PE=1 SV=1 0.005 2.916 3 1 1 1 490 54.2 6.74 37336.87109 22503.92773 7750.819336 36053.76172 1 1 1 1 metabolic process membrane;mitochondrion catalytic activity "Pf00106, Pf02036, Pf14864" 72479 ENSMUSG00000028383.17 Hsdl2 4 0 Low Q9CRA0 Ecto-ADP-ribosyltransferase 4 OS=Mus musculus OX=10090 GN=Art4 PE=1 SV=1 0.076 1.178 2 1 1 1 300 33.1 8.47 metabolic process membrane catalytic activity Pf01129 109978 ENSMUSG00000030217.2 Art4 6 Post-translational modification: synthesis of GPI-anchored proteins 0 High Q8JZQ9 Eukaryotic translation initiation factor 3 subunit B OS=Mus musculus OX=10090 GN=Eif3b PE=1 SV=1 0.006 2.427 1 1 1 1 803 91.3 5.02 6336.137695 4615.157227 1 1 metabolic process;regulation of biological process cytoplasm protein binding;RNA binding "Pf00076, Pf08662, Pf13893, Pf14259" 27979 ENSMUSG00000056076.13 Eif3b 5 "Formation of a pool of free 40S subunits; L13a-mediated translational silencing of Ceruloplasmin expression; Ribosomal scanning and start codon recognition; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation; GTP hydrolysis and joining of the 60S ribosomal subunit" RNA transport 0 Medium Q9WVA4 Transgelin-2 OS=Mus musculus OX=10090 GN=Tagln2 PE=1 SV=4 0.012 2.041 6 1 1 1 199 22.4 8.24 cell differentiation protein binding "Pf00307, Pf00402" 21346 ENSMUSG00000026547.15 Tagln2 1 Platelet degranulation 0 Medium O88983 Syntaxin-8 OS=Mus musculus OX=10090 GN=Stx8 PE=1 SV=1 0.013 1.95 3 1 1 1 236 26.9 5.01 21379.33203 10113.7959 1 1 cell organization and biogenesis;regulation of biological process;transport cytosol;endosome;membrane protein binding Pf05739 55943 ENSMUSG00000020903.13 Stx8 11 SNARE interactions in vesicular transport 0 Medium Q8K0G8 Epithelial splicing regulatory protein 2 OS=Mus musculus OX=10090 GN=Esrp2 PE=1 SV=1 0.047 1.347 4 1 1 1 717 77.3 6.38 metabolic process;regulation of biological process nucleus RNA binding "Pf00076, Pf14259" 77411 ENSMUSG00000084128.10 Esrp2 8 FGFR2 alternative splicing 0 High Q9D1J1 Adaptin ear-binding coat-associated protein 2 OS=Mus musculus OX=10090 GN=Necap2 PE=1 SV=1 0.004 2.789 7 1 1 1 266 28.6 7.94 transport membrane Pf07933 66147 ENSMUSG00000028923.14 Necap2 4 0 Medium D3Z276 RIKEN cDNA 2410002F23 gene (Fragment) OS=Mus musculus OX=10090 GN=2410002F23Rik PE=1 SV=7 0.012 2.041 6 1 1 1 156 17.9 5 ENSMUSG00000045411.16 7 0 Medium P28660 Nck-associated protein 1 OS=Mus musculus OX=10090 GN=Nckap1 PE=1 SV=2 0.026 1.581 1 1 1 1 1128 128.7 6.62 116452.4375 36085.37891 1 1 cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus cytoplasm;membrane protein binding Pf09735 50884 ENSMUSG00000027002.13 Nckap1 2 RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway; Regulation of actin dynamics for phagocytic cup formation Regulation of actin cytoskeleton 0 High Q9CPZ6 ORM1-like protein 3 OS=Mus musculus OX=10090 GN=Ormdl3 PE=2 SV=1 0.007 2.251 10 1 1 1 153 17.5 9.64 Acetyl [N-Term] cellular homeostasis;metabolic process;regulation of biological process endoplasmic reticulum;membrane Pf04061 66612 ENSMUSG00000038150.7 Ormdl3 11 Neutrophil degranulation; Sphingolipid de novo biosynthesis 0 High Q61406 Complement factor H-related 1 OS=Mus musculus OX=10090 GN=Cfhr1 PE=1 SV=1 0.005 2.554 2 1 1 1 343 38.4 7.93 regulation of biological process protein binding Pf00084 50702 ENSMUSG00000057037.8 Cfhr1 1 Regulation of Complement cascade 0 Medium B1AUB9 Nuclear factor 1 OS=Mus musculus OX=10090 GN=Nfia PE=1 SV=1 0.019 1.781 2 1 1 1 487 53.6 9.01 17629.17383 1 cell organization and biogenesis;metabolic process;regulation of biological process nucleus DNA binding;protein binding "Pf00859, Pf03165, Pf10524" 18027 ENSMUSG00000028565.18 Nfia 4 0 Medium P54728 UV excision repair protein RAD23 homolog B OS=Mus musculus OX=10090 GN=Rad23b PE=1 SV=2 0.012 2.045 3 1 1 1 416 43.5 4.83 3743.030273 2082.562256 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;nucleus;proteasome DNA binding;protein binding "Pf00240, Pf00627, Pf09280, Pf11976, Pf13881" 19359 ENSMUSG00000028426.10 Rad23b 4 N-glycan trimming in the ER and Calnexin/Calreticulin cycle; DNA Damage Recognition in GG-NER; Formation of Incision Complex in GG-NER Nucleotide excision repair; Protein processing in endoplasmic reticulum 0 High P61027 Ras-related protein Rab-10 OS=Mus musculus OX=10090 GN=Rab10 PE=1 SV=1 0.002 4.552 6 1 1 1 200 22.5 8.38 cell differentiation;cell organization and biogenesis;regulation of biological process;response to stimulus;transport endoplasmic reticulum;endosome;Golgi;membrane catalytic activity;nucleotide binding;protein binding "Pf00025, Pf00071, Pf04670, Pf08477" 19325 ENSMUSG00000020671.9 Rab10 12 RAB GEFs exchange GTP for GDP on RABs; Neutrophil degranulation Endocytosis; AMPK signaling pathway 0 Medium Q8VDM6 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Mus musculus OX=10090 GN=Hnrnpul1 PE=1 SV=1 0.014 1.913 2 1 1 1 859 95.9 6.58 3116.69458 1 metabolic process;regulation of biological process;response to stimulus nucleus protein binding;RNA binding "Pf00622, Pf02037, Pf13671" 232989 ENSMUSG00000040725.13 Hnrnpul1 7 mRNA Splicing - Major Pathway Influenza A 0 Low E9Q2X6 Structural maintenance of chromosomes protein OS=Mus musculus OX=10090 GN=Smc4 PE=1 SV=1 0.075 1.184 1 1 1 1 1261 144.1 7.58 2006.42395 53581.82813 1 1 cell organization and biogenesis;metabolic process chromosome;nucleus nucleotide binding;protein binding "Pf02463, Pf06470, Pf13304, Pf13476, Pf13555" ENSMUSG00000034349.14 3 0 Medium P57784 U2 small nuclear ribonucleoprotein A' OS=Mus musculus OX=10090 GN=Snrpa1 PE=1 SV=2 0.035 1.447 5 1 1 1 255 28.3 8.62 metabolic process nucleus;spliceosomal complex protein binding;RNA binding "Pf12799, Pf13855, Pf14580" 68981 ENSMUSG00000030512.13 Snrpa1 7 mRNA Splicing - Major Pathway Spliceosome 0 High Q9CQZ0 ORM1-like protein 2 OS=Mus musculus OX=10090 GN=Ormdl2 PE=1 SV=1 0.004 2.845 10 1 1 1 153 17.4 9.64 90130.27344 1 Acetyl [N-Term] cellular homeostasis;metabolic process;regulation of biological process endoplasmic reticulum;membrane Pf04061 66844 ENSMUSG00000025353.5 Ormdl2 10 Sphingolipid de novo biosynthesis 0 High Q8BGG7 Ubiquitin-associated and SH3 domain-containing protein B OS=Mus musculus OX=10090 GN=Ubash3b PE=1 SV=1 0.002 3.918 2 1 1 1 638 71.4 6.81 metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus catalytic activity;protein binding "Pf00018, Pf00300, Pf00627, Pf13563, Pf14604" 72828 ENSMUSG00000032020.15 Ubash3b 9 0 High Q99LC9 Peroxisome assembly factor 2 OS=Mus musculus OX=10090 GN=Pex6 PE=1 SV=1 0.005 3.145 2 1 1 1 981 104.5 7.34 cell organization and biogenesis;regulation of biological process;transport cytoplasm;cytosol;membrane catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00004, Pf00910, Pf05729, Pf07724, Pf13086, Pf13191, Pf13207, Pf13245" 224824 ENSMUSG00000002763.16 Pex6 17 Peroxisome 0 High Q9JHI7 Exosome complex component RRP45 OS=Mus musculus OX=10090 GN=Exosc9 PE=1 SV=1 0.006 2.426 3 1 1 1 438 48.9 5.11 metabolic process;regulation of biological process chromosome;cytoplasm;nucleus catalytic activity;protein binding;RNA binding "Pf01138, Pf03725" 50911 ENSMUSG00000027714.11 Exosc9 3 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease; Major pathway of rRNA processing in the nucleolus and cytosol; KSRP (KHSRP) binds and destabilizes mRNA RNA degradation 0 Medium A0A0A6YWI9 Immunoglobulin heavy variable V1-11 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-11 PE=4 SV=1 0.031 1.5 11 1 1 1 117 12.9 8.28 257114.8125 30582.57813 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000102888.1 12 0 Low E9Q4M2 Hormone-sensitive lipase OS=Mus musculus OX=10090 GN=Lipe PE=1 SV=1 0.052 1.329 1 1 1 1 1072 117.2 6.83 1 1 60882.38672 111458.4531 9945.493164 14444.6748 1 1 1 1 metabolic process cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;protein binding;RNA binding "Pf06350, Pf07859, Pf10340, Pf12695" 16890 ENSMUSG00000003123.15 Lipe 7 0 Medium Q9CQA0 Centromere protein M OS=Mus musculus OX=10090 GN=Cenpm PE=2 SV=1 0.015 1.873 13 1 1 1 180 20 7.83 174651.9844 19413.00781 15792.80273 1 1 1 chromosome;cytoplasm;cytosol;nucleus Pf11111 66570 ENSMUSG00000068101.10 Cenpm 15 Resolution of Sister Chromatid Cohesion; Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal; Separation of Sister Chromatids; RHO GTPases Activate Formins; Deposition of new CENPA-containing nucleosomes at the centromere 0 Medium P50295 Arylamine N-acetyltransferase 2 OS=Mus musculus OX=10090 GN=Nat2 PE=1 SV=1 0.019 1.774 4 1 1 1 290 33.7 5.88 metabolic process cytoplasm;cytosol catalytic activity Pf00797 17961 ENSMUSG00000051147.10 Nat2 8 Acetylation Caffeine metabolism; Metabolic pathways; Drug metabolism - other enzymes; Chemical carcinogenesis 0 High E9QAF4 "Pleckstrin homology-like domain, family B, member 3 OS=Mus musculus OX=10090 GN=Phldb3 PE=1 SV=1" 0.006 2.373 1 1 1 1 648 72.7 6.24 11706.49316 9623.398438 1 1 protein binding "Pf00169, Pf12128, Pf14593" 232970 ENSMUSG00000074277.4 Phldb3 7 0 High Q8CBY8 Dynactin subunit 4 OS=Mus musculus OX=10090 GN=Dctn4 PE=1 SV=1 0.005 2.51 2 1 1 1 467 53 7.72 8775.734375 1 chromosome;cytoplasm;cytoskeleton protein binding Pf05502 67665 Dctn4 18 COPI-independent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) Huntington's disease; Vasopressin-regulated water reabsorption 0 Low Q8VCS3 Glycosaminoglycan xylosylkinase OS=Mus musculus OX=10090 GN=Fam20b PE=1 SV=1 0.076 1.159 2 1 1 1 409 46.6 6.95 metabolic process Golgi;membrane catalytic activity;enzyme regulator activity;metal ion binding;nucleotide binding Pf06702 215015 ENSMUSG00000033557.17 Fam20b 1 0 Medium A0A494BAM2 RNA 3'-terminal phosphate cyclase-like protein OS=Mus musculus OX=10090 GN=Rcl1 PE=1 SV=1 0.013 2.011 4 1 1 1 337 36.7 9 0 Medium Q3U2P1 Protein transport protein Sec24A OS=Mus musculus OX=10090 GN=Sec24a PE=1 SV=1 0.024 1.603 1 1 1 1 1090 118.7 7.83 16392.27734 8008.632813 1 1 cell organization and biogenesis;regulation of biological process;transport cytoplasm;cytosol;endoplasmic reticulum;membrane metal ion binding "Pf00626, Pf04810, Pf04811, Pf04815, Pf07271, Pf08033" 77371 ENSMUSG00000036391.16 Sec24a 11 "Cargo concentration in the ER; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; COPII (Coat Protein 2) Mediated Vesicle Transport; MHC class II antigen presentation" Protein processing in endoplasmic reticulum 0 Medium O70194 Eukaryotic translation initiation factor 3 subunit D OS=Mus musculus OX=10090 GN=Eif3d PE=1 SV=2 0.023 1.634 3 1 1 1 548 63.9 6.05 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;membrane RNA binding Pf05091 55944 ENSMUSG00000016554.8 Eif3d 15 "Formation of a pool of free 40S subunits; L13a-mediated translational silencing of Ceruloplasmin expression; Ribosomal scanning and start codon recognition; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation; GTP hydrolysis and joining of the 60S ribosomal subunit" RNA transport 0 Medium Q9CZ13 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Mus musculus OX=10090 GN=Uqcrc1 PE=1 SV=2" 0.02 1.747 2 1 1 1 480 52.8 6.21 18522.83789 100487.9063 46100.68359 22038.30078 1 1 1 1 metabolic process;response to stimulus;transport cytosol;membrane;mitochondrion catalytic activity;metal ion binding;protein binding "Pf00675, Pf05193, Pf08367" 22273 ENSMUSG00000025651.14; ENSMUSG00000107235.3 Uqcrc1 9; CHR_MG117_PATCH Respiratory electron transport Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 Low D6RJ68 Four and a half LIM domains protein 3 OS=Mus musculus OX=10090 GN=Fhl3 PE=1 SV=1 0.06 1.264 6 1 1 1 120 13.6 4.5 3086.784912 1 cell organization and biogenesis nucleus metal ion binding;protein binding Pf00412 ENSMUSG00000032643.12 4 0 Medium E9Q8J5 Predicted gene 597 OS=Mus musculus OX=10090 GN=Gm597 PE=1 SV=1 0.026 1.582 3 1 1 1 896 100 8.98 membrane Pf14650 210962 ENSMUSG00000048411.4 Gm597 1 0 Medium Q9JJK5 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein OS=Mus musculus OX=10090 GN=Herpud1 PE=1 SV=1 0.03 1.525 7 1 1 1 391 43.9 5.53 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport endoplasmic reticulum;membrane protein binding Pf00240 64209 ENSMUSG00000031770.16 Herpud1 8 Protein processing in endoplasmic reticulum 0 High Q80SW1 S-adenosylhomocysteine hydrolase-like protein 1 OS=Mus musculus OX=10090 GN=Ahcyl1 PE=1 SV=1 0.005 2.51 2 1 1 1 530 58.9 6.89 16950.29688 1 metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;endoplasmic reticulum;membrane catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00670, Pf01262, Pf01488, Pf02254, Pf02826, Pf05221" 229709 ENSMUSG00000027893.14 Ahcyl1 3 Ion homeostasis Metabolic pathways; Cysteine and methionine metabolism 0 Medium Q8BGZ4 Cell division cycle protein 23 homolog OS=Mus musculus OX=10090 GN=Cdc23 PE=1 SV=2 0.026 1.571 2 1 1 1 597 68.5 7.18 13740.91016 1 cell division;metabolic process;regulation of biological process catalytic activity;protein binding "Pf00515, Pf01981, Pf04049, Pf13414, Pf13432" 52563 Cdc23 18 Progesterone-mediated oocyte maturation; Ubiquitin mediated proteolysis; HTLV-I infection; Oocyte meiosis; Cell cycle 0 Medium Q8VG76 Olfactory receptor OS=Mus musculus OX=10090 GN=Olfr910 PE=3 SV=1 0.02 1.694 5 1 1 1 310 34.8 8.32 11747.80371 1 regulation of biological process;response to stimulus membrane receptor activity;signal transducer activity "Pf00001, Pf13853" 258807 ENSMUSG00000060114.4 Olfr910 9 Olfactory transduction 0 Medium A3KFV1 Collagen alpha-1(XVI) chain (Fragment) OS=Mus musculus OX=10090 GN=Col16a1 PE=4 SV=1 0.049 1.343 100 1 1 1 22 2.4 7.25 564376.75 528265.3125 202053.9219 204734.9219 1 1 1 1 cell organization and biogenesis;regulation of biological process;response to stimulus extracellular protein binding 107581 ENSMUSG00000040690.15 Col16a1 4 0 Medium D3Z191 Transmembrane protein 106B (Fragment) OS=Mus musculus OX=10090 GN=Tmem106b PE=1 SV=8 0.027 1.564 14 1 1 1 185 20.7 8.56 membrane Pf07092 ENSMUSG00000029571.14 6 0 Medium F6ZX28 ATP-dependent RNA helicase DDX18 (Fragment) OS=Mus musculus OX=10090 GN=Ddx18 PE=1 SV=1 0.018 1.8 6 1 1 1 171 19.7 9.13 4675.273926 9533.029297 4427.200195 1 1 1 Pf00271 ENSMUSG00000001674.11 1 0 High Q91XH6 Vesicle transport through interaction with t-SNAREs 1B homolog OS=Mus musculus OX=10090 GN=Vti1b PE=1 SV=1 0.004 2.609 6 1 1 1 232 26.7 9.04 Met-loss+Acetyl [N-Term] cell organization and biogenesis;regulation of biological process;transport cytosol;endosome;Golgi;membrane;vacuole protein binding "Pf03908, Pf05008, Pf12352" 53612 ENSMUSG00000021124.13 Vti1b 12 Platelet degranulation SNARE interactions in vesicular transport 0 Low E9PX47 Olfactory receptor OS=Mus musculus OX=10090 GN=Olfr544 PE=3 SV=1 0.078 1.142 10 1 1 1 334 37.2 9.47 regulation of biological process;response to stimulus membrane receptor activity;signal transducer activity "Pf00001, Pf13853" 257926 ENSMUSG00000043925.7 Olfr544 7 Olfactory transduction 0 High A0A0U1RNI2 Serine/threonine-protein phosphatase 6 regulatory subunit 1 (Fragment) OS=Mus musculus OX=10090 GN=Ppp6r1 PE=1 SV=1 0.004 2.865 8 1 1 1 253 28.8 4.87 37903.55469 4816.533203 1 1 Pf04499 ENSMUSG00000052296.7 7 0 Low Q99JI4 26S proteasome non-ATPase regulatory subunit 6 OS=Mus musculus OX=10090 GN=Psmd6 PE=1 SV=1 0.057 1.293 2 1 1 1 389 45.5 5.52 metabolic process;regulation of biological process proteasome enzyme regulator activity;protein binding "Pf01399, Pf10602" 66413 ENSMUSG00000021737.3 Psmd6 14 The role of GTSE1 in G2/M progression after G2 checkpoint; CDT1 association with the CDC6:ORC:origin complex; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Degradation of beta-catenin by the destruction complex; Autodegradation of the E3 ubiquitin ligase COP1; UCH proteinases; MAPK6/MAPK4 signaling; SCF-beta-TrCP mediated degradation of Emi1; CDK-mediated phosphorylation and removal of Cdc6; Separation of Sister Chromatids; SCF(Skp2)-mediated degradation of p27/p21; GLI3 is processed to GLI3R by the proteasome; Ub-specific processing proteases; Regulation of ornithine decarboxylase (ODC); Activation of NF-kappaB in B cells; Degradation of GLI1 by the proteasome; FCERI mediated NF-kB activation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Hedgehog ligand biogenesis; Neutrophil degranulation; Downstream TCR signaling; Autodegradation of Cdh1 by Cdh1:APC/C; Regulation of RAS by GAPs; Interleukin-1 family signaling; Asymmetric localization of PCP proteins; G2/M Checkpoints; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Regulation of PTEN stability and activity; Ubiquitin-dependent degradation of Cyclin D1; NIK-->noncanonical NF-kB signaling; Removal of licensing factors from origins; M/G1 Transition; Interleukin-20 family signaling; Regulation of RUNX2 expression and activity; Cross-presentation of soluble exogenous antigens (endosomes); ABC-family proteins mediated transport; APC/C:Cdc20 mediated degradation of Securin; Regulation of DNA replication; Dectin-1 mediated noncanonical NF-kB signaling; Antigen processing: Ubiquitination & Proteasome degradation; Orc1 removal from chromatin; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of RUNX3 expression and activity; Hedgehog 'on' state; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Degradation of DVL; Degradation of AXIN Proteasome; Epstein-Barr virus infection 0 Medium Q5XJY5 Coatomer subunit delta OS=Mus musculus OX=10090 GN=Arcn1 PE=1 SV=2 0.022 1.658 2 1 1 1 511 57.2 6.21 5698.567871 1 Met-loss [N-Term] response to stimulus;transport cytoplasm;endoplasmic reticulum;Golgi;membrane RNA binding Pf00928 213827 ENSMUSG00000032096.16 Arcn1 9 COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic 0 Medium Q8CG76 Aflatoxin B1 aldehyde reductase member 2 OS=Mus musculus OX=10090 GN=Akr7a2 PE=1 SV=3 0.012 2.085 5 1 1 1 367 40.6 8.12 16452.93555 20131.4707 1 1 metabolic process cytoplasm;cytosol;Golgi;mitochondrion catalytic activity Pf00248 110198 ENSMUSG00000028743.7 Akr7a5 4 Aflatoxin activation and detoxification Metabolism of xenobiotics by cytochrome P450 0 Medium D3YU83 Cell growth-regulating nucleolar protein (Fragment) OS=Mus musculus OX=10090 GN=Lyar PE=1 SV=1 0.019 1.775 14 1 1 1 99 11.2 8.46 10708.83301 64741.73047 1 1 Met-loss [N-Term] Pf08790 ENSMUSG00000067367.9 5 0 Medium Q8VCX1 Aldo-keto reductase family 1 member D1 OS=Mus musculus OX=10090 GN=Akr1d1 PE=1 SV=1 0.02 1.666 3 1 1 1 325 37.3 6.9 metabolic process cytoplasm;cytosol catalytic activity Pf00248 208665 ENSMUSG00000038641.12 Akr1d1 6 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; Synthesis of bile acids and bile salts via 24-hydroxycholesterol; Synthesis of bile acids and bile salts via 27-hydroxycholesterol Steroid hormone biosynthesis; Metabolic pathways; Primary bile acid biosynthesis 0 High A0A338P7E3 Ribonuclease T2-B OS=Mus musculus OX=10090 GN=Rnaset2b PE=1 SV=1 0.005 3.225 9 1 1 1 163 18.8 7.08 0 High A0A1B0GRG7 Erlin-2 (Fragment) OS=Mus musculus OX=10090 GN=Erlin2 PE=1 SV=1 0.009 2.234 14 1 1 1 85 9 7.46 99799.625 1 metabolic process endoplasmic reticulum protein binding Pf01145 ENSMUSG00000031483.8 8 0 High F6Q269 JmjC domain-containing protein 8 OS=Mus musculus OX=10090 GN=Jmjd8 PE=1 SV=2 0.005 3.059 7 1 1 1 186 20.9 7.3 123647.6484 1 0 Low Q3TVF6 Protein FAM207A (Fragment) OS=Mus musculus OX=10090 GN=Fam207a PE=1 SV=1 0.083 1.088 6 1 1 1 200 22.9 10.64 Pf15341 108707 ENSMUSG00000032977.9 1810008A18Rik; Fam207a 10 0 High Q8BJL1 F-box only protein 30 OS=Mus musculus OX=10090 GN=Fbxo30 PE=1 SV=2 0.005 2.487 1 1 1 1 746 82.6 5.26 metabolic process catalytic activity;metal ion binding;protein binding "Pf00646, Pf12937" 71865 ENSMUSG00000047648.13 Fbxo30 10 Neddylation; Antigen processing: Ubiquitination & Proteasome degradation 0 High P16294 Coagulation factor IX OS=Mus musculus OX=10090 GN=F9 PE=2 SV=3 0.002 4.708 3 1 1 1 471 52.9 5.44 coagulation;metabolic process extracellular catalytic activity;metal ion binding;protein binding "Pf00008, Pf00089, Pf00594, Pf13365, Pf14670" 14071 ENSMUSG00000031138.4 F9 X Removal of aminoterminal propeptides from gamma-carboxylated proteins; Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus; Intrinsic Pathway of Fibrin Clot Formation; Gamma-carboxylation of protein precursors; Extrinsic Pathway of Fibrin Clot Formation Complement and coagulation cascades 0 Low Q5XG71 Small subunit processome component 20 homolog OS=Mus musculus OX=10090 GN=Utp20 PE=1 SV=2 0.076 1.177 1 1 1 1 2788 317.5 8.09 11017.59277 15937.4834 1 1 metabolic process membrane;nucleus RNA binding Pf07539 70683 Utp20 10 0 Medium P14246 "Solute carrier family 2, facilitated glucose transporter member 2 OS=Mus musculus OX=10090 GN=Slc2a2 PE=1 SV=3" 0.019 1.765 2 1 1 1 523 57.1 6.73 transport cytoplasm;cytosol;endosome;membrane protein binding;transporter activity "Pf00083, Pf07690, Pf13347" 20526 ENSMUSG00000027690.13 Slc2a2 3 Intestinal hexose absorption; Regulation of insulin secretion; Cellular hexose transport Type II diabetes mellitus; Carbohydrate digestion and absorption; Prolactin signaling pathway; Insulin resistance; Maturity onset diabetes of the young; Insulin secretion; Central carbon metabolism in cancer; Glucagon signaling pathway 0 High Q8VCC1 15-hydroxyprostaglandin dehydrogenase [NAD(+)] OS=Mus musculus OX=10090 GN=Hpgd PE=1 SV=1 0.003 3.687 4 1 1 1 269 29.2 6.54 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane catalytic activity;nucleotide binding;protein binding;receptor activity;signal transducer activity "Pf00106, Pf01370, Pf08659, Pf13561" 15446 ENSMUSG00000031613.9 Hpgd 8 Synthesis of Lipoxins (LX); Arachidonic acid metabolism Transcriptional misregulation in cancer 0 Medium Q9D1D4 Transmembrane emp24 domain-containing protein 10 OS=Mus musculus OX=10090 GN=Tmed10 PE=1 SV=1 0.021 1.717 4 1 1 1 219 24.9 6.7 cell organization and biogenesis;regulation of biological process;response to stimulus;transport endoplasmic reticulum;Golgi;membrane protein binding Pf01105 68581 ENSMUSG00000021248.8 Tmed10 12 Cargo concentration in the ER; COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic; COPII (Coat Protein 2) Mediated Vesicle Transport 0 Medium A0A075B5W6 Immunoglobulin heavy variable 1-55 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-55 PE=1 SV=1 0.018 1.792 21 1 1 1 117 12.7 8.27 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000095589.2 12 0 High Q3U6K9 Phosphoserine aminotransferase OS=Mus musculus OX=10090 GN=Psat1 PE=1 SV=1 0.004 2.698 4 1 1 1 367 40.2 7.65 11342.32813 1 metabolic process cytoplasm;cytosol catalytic activity Pf00266 107272 ENSMUSG00000024640.9 Psat1 19 0 Medium P62331 ADP-ribosylation factor 6 OS=Mus musculus OX=10090 GN=Arf6 PE=1 SV=2 0.049 1.341 9 1 1 1 175 20.1 8.95 cell death;cell differentiation;cell division;cell organization and biogenesis;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;endosome;Golgi;membrane catalytic activity;nucleotide binding;protein binding;signal transducer activity "Pf00025, Pf00071, Pf00503, Pf04670, Pf08477, Pf09439" 11845 ENSMUSG00000044147.7 Arf6 12 Clathrin-mediated endocytosis; MET receptor recycling; TBC/RABGAPs Endocytosis; Phospholipase D signaling pathway; Ras signaling pathway; Fc gamma R-mediated phagocytosis 0 Low Q69ZK7 Protein FAM214A OS=Mus musculus OX=10090 GN=Fam214a PE=2 SV=3 0.062 1.252 2 1 1 1 1075 119.2 7.74 "Pf13889, Pf13915" 235493 ENSMUSG00000034858.16 BC031353; Fam214a 9 0 Medium A0A2I3BPR1 Collagen triple helix repeat-containing protein 1 OS=Mus musculus OX=10090 GN=Cthrc1 PE=1 SV=1 0.014 1.902 5 1 1 1 171 18.7 7.94 0 High Q91YL3 Uridine-cytidine kinase-like 1 OS=Mus musculus OX=10090 GN=Uckl1 PE=1 SV=1 0.006 2.423 1 1 1 1 548 60.8 7.15 4687.768555 8354.585938 5377.339844 1 1 1 metabolic process cytoplasm;cytosol;nucleus catalytic activity;enzyme regulator activity;nucleotide binding "Pf00485, Pf07931, Pf13207, Pf14681" 68556 ENSMUSG00000089917.7 Uckl1 2 Pyrimidine salvage Metabolic pathways; Pyrimidine metabolism; Drug metabolism - other enzymes 0 High H7BX01 "Dynamin-like 120 kDa protein, mitochondrial OS=Mus musculus OX=10090 GN=Opa1 PE=1 SV=1" 0.005 3.215 1 1 1 1 978 113.2 7.33 26509.9375 8592.115234 1 1 cell death;cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytosol;membrane;mitochondrion catalytic activity;nucleotide binding;protein binding "Pf00350, Pf01926" 74143 ENSMUSG00000038084.16 Opa1 16 0 High P28843 Dipeptidyl peptidase 4 OS=Mus musculus OX=10090 GN=Dpp4 PE=1 SV=3 0.005 3.203 1 1 1 1 760 87.4 6.42 cellular component movement;defense response;metabolic process;regulation of biological process;response to stimulus cell surface;endoplasmic reticulum;extracellular;Golgi;membrane catalytic activity;protein binding;receptor activity "Pf00326, Pf00930, Pf01738, Pf12695, Pf12697" 13482 ENSMUSG00000035000.8 Dpp4 2 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP); Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" Protein digestion and absorption 0 High O35309 N-myc-interactor OS=Mus musculus OX=10090 GN=Nmi PE=1 SV=1 0.004 2.813 5 1 1 1 314 35.2 5.05 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol protein binding "Pf07292, Pf07334" 64685 ENSMUSG00000026946.9 Nmi 2 0 Low E9QK39 Ribosomal protein S6 kinase OS=Mus musculus OX=10090 GN=Rps6ka6 PE=1 SV=1 0.055 1.307 1 1 1 1 860 97.4 7.56 metabolic process;regulation of biological process;response to stimulus cytoplasm;mitochondrion;nucleus catalytic activity;metal ion binding;nucleotide binding "Pf00069, Pf00433, Pf07714, Pf14531" 67071 ENSMUSG00000025665.16 Rps6ka6 X RSK activation mTOR signaling pathway; MAPK signaling pathway; Progesterone-mediated oocyte maturation; Long-term potentiation; Insulin resistance; Oocyte meiosis; Neurotrophin signaling pathway 0 High A0A140LHN0 Protein YIF1B (Fragment) OS=Mus musculus OX=10090 GN=Yif1b PE=1 SV=1 0.006 2.365 8 1 1 1 315 34.3 7.03 2941.453369 1 membrane Pf03878 ENSMUSG00000030588.12 7 0 Medium A2AJ72 Far upstream element (FUSE)-binding protein 3 OS=Mus musculus OX=10090 GN=Fubp3 PE=1 SV=1 0.03 1.529 3 1 1 1 569 61.4 8.28 metabolic process;regulation of biological process cytoplasm;membrane;nucleus DNA binding;RNA binding "Pf00013, Pf07650, Pf13014" 320267 ENSMUSG00000026843.15 Fubp3 2 0 High Q9CPS7 RNA-binding protein PNO1 OS=Mus musculus OX=10090 GN=Pno1 PE=1 SV=1 0.002 4.132 7 1 1 1 248 27.4 9.79 Acetyl [N-Term] nucleus RNA binding Pf00013 66249 ENSMUSG00000020116.7 Pno1 11 0 Medium A0A494BAU4 Cytosolic purine 5'-nucleotidase OS=Mus musculus OX=10090 GN=Nt5c2 PE=1 SV=1 0.04 1.417 21 1 1 1 62 7.2 9.48 8652.119141 1 0 Medium Q3TLD5 Unconventional prefoldin RPB5 interactor OS=Mus musculus OX=10090 GN=Uri1 PE=1 SV=2 0.018 1.785 2 1 1 1 531 59 5.07 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;mitochondrion;nucleus enzyme regulator activity;protein binding "Pf02996, Pf13758" 19777 ENSMUSG00000030421.9 C80913; Uri1 7 0 Low Q9D8T7 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Mus musculus OX=10090 GN=Slirp PE=1 SV=2" 0.083 1.089 11 1 1 1 112 12.6 9.82 cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process cytoplasm;mitochondrion;nucleus RNA binding "Pf00076, Pf05172, Pf13893, Pf14259" 380773 ENSMUSG00000021040.15 Slirp 12 0 Medium Q3UFY0 Ribosomal RNA processing protein 36 homolog OS=Mus musculus OX=10090 GN=Rrp36 PE=1 SV=1 0.029 1.552 3 1 1 1 244 28.6 10.56 metabolic process nucleus RNA binding Pf06102 224823 Rrp36 17 0 High E9Q7W0 Recombining-binding protein suppressor of hairless OS=Mus musculus OX=10090 GN=Rbpj PE=1 SV=1 0.004 2.865 2 1 1 1 485 54.3 8.02 9736.736328 1 cell differentiation;cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;nucleus DNA binding;protein binding "Pf09270, Pf09271" 19664 ENSMUSG00000039191.12 Rbpj 5 0 Low Q7TN16 Hedgehog-interacting protein OS=Mus musculus OX=10090 GN=Hhip PE=1 SV=2 0.07 1.223 2 1 1 1 700 78.5 7.91 164239.2656 1 cell proliferation;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;extracellular;membrane;nucleus catalytic activity;metal ion binding;protein binding "Pf03024, Pf07995" 15245 ENSMUSG00000064325.4 Hhip 8 Ligand-receptor interactions Basal cell carcinoma; Pathways in cancer; Hedgehog signaling pathway; cAMP signaling pathway 0 Medium Q9DC70 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial OS=Mus musculus OX=10090 GN=Ndufs7 PE=1 SV=1" 0.014 1.877 12 1 1 1 224 24.7 9.92 28447.90234 1 cell organization and biogenesis;metabolic process;transport membrane;mitochondrion catalytic activity;metal ion binding;protein binding Pf01058 75406 ENSMUSG00000020153.14 Ndufs7 10 Complex I biogenesis Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 Medium Q69ZX8 Actin-binding LIM protein 3 OS=Mus musculus OX=10090 GN=Ablim3 PE=1 SV=2 0.036 1.44 2 1 1 1 682 77.6 8.54 2330.936768 11512.1709 1 1 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm metal ion binding;protein binding "Pf00412, Pf02209" 319713 ENSMUSG00000032735.14 Ablim3 18 Axon guidance 0 High Q8CIZ8 von Willebrand factor OS=Mus musculus OX=10090 GN=Vwf PE=1 SV=2 0.007 2.243 0 1 1 1 2813 309.1 5.5 30663.91992 1 cell organization and biogenesis;coagulation cytoplasm;endoplasmic reticulum;extracellular protein binding "Pf00092, Pf00093, Pf00094, Pf01826, Pf08742" 22371 Vwf 6 Focal adhesion; Platelet activation; Complement and coagulation cascades; ECM-receptor interaction; PI3K-Akt signaling pathway 0 High Q8BUV3 Gephyrin OS=Mus musculus OX=10090 GN=Gphn PE=1 SV=2 0.006 2.4 1 1 1 1 769 83.2 5.6 16667.99219 1 cell organization and biogenesis;metabolic process;response to stimulus cytoplasm;cytoskeleton;membrane catalytic activity;metal ion binding;nucleotide binding;protein binding;structural molecule activity "Pf00994, Pf03453, Pf03454" 268566 ENSMUSG00000047454.12 Gphn 12 Molybdenum cofactor biosynthesis GABAergic synapse; Metabolic pathways; Folate biosynthesis 0 Medium A0A0A6YX50 Protoporphyrinogen oxidase (Fragment) OS=Mus musculus OX=10090 GN=Ppox PE=1 SV=1 0.013 1.976 3 1 1 1 389 41.2 8.84 10246.20996 6900.646973 16454.46484 1 1 1 metabolic process membrane;mitochondrion catalytic activity "Pf01266, Pf01593, Pf13450" ENSMUSG00000062729.11 1 0 High P02463 Collagen alpha-1(IV) chain OS=Mus musculus OX=10090 GN=Col4a1 PE=1 SV=4 0.007 2.251 1 1 1 1 1669 160.6 8.24 18037.81641 13046.78516 6301.602539 1 1 1 cell differentiation;cell organization and biogenesis;regulation of biological process;response to stimulus extracellular protein binding;structural molecule activity "Pf01391, Pf01413" 12826 ENSMUSG00000031502.11 Col4a1 8 Anchoring fibril formation; Laminin interactions; Crosslinking of collagen fibrils; Collagen chain trimerization; Integrin cell surface interactions; NCAM1 interactions; Collagen degradation; Non-integrin membrane-ECM interactions; Signaling by PDGF AGE-RAGE signaling pathway in diabetic complications; Focal adhesion; Protein digestion and absorption; Small cell lung cancer; Pathways in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway; Amoebiasis 0 Low E9Q5M1 Activated CDC42 kinase 1 (Fragment) OS=Mus musculus OX=10090 GN=Tnk2 PE=1 SV=10 0.076 1.157 3 1 1 1 311 33.8 5.03 0 High Q8QZY9 Splicing factor 3B subunit 4 OS=Mus musculus OX=10090 GN=Sf3b4 PE=1 SV=1 0.007 2.284 3 1 1 1 424 44.3 8.56 49406.61328 1 metabolic process;regulation of biological process nucleus;spliceosomal complex RNA binding "Pf00076, Pf13893, Pf14259" 107701 ENSMUSG00000068856.3 Sf3b4 3 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway Spliceosome 0 Low A0JNU3 60 kDa lysophospholipase OS=Mus musculus OX=10090 GN=Aspg PE=1 SV=1 0.076 1.155 3 1 1 1 564 60.6 5.88 metabolic process catalytic activity;protein binding "Pf00710, Pf12796, Pf13637, Pf13857" 104816 ENSMUSG00000037686.5 Aspg 12 Amino acid synthesis and interconversion (transamination) 0 High A2BE93 Protein SET (Fragment) OS=Mus musculus OX=10090 GN=Set PE=1 SV=1 0.005 3.294 5 1 1 1 215 24.9 5.55 cell organization and biogenesis;regulation of biological process cytoplasm;endoplasmic reticulum;nucleus DNA binding Pf00956 56086 ENSMUSG00000054766.13 Set 2 0 High Q8VBZ3 Cleft lip and palate transmembrane protein 1 homolog OS=Mus musculus OX=10090 GN=Clptm1 PE=1 SV=1 0 5.658 3 1 1 1 664 75.2 6.3 19648.14453 1 cell differentiation;development;regulation of biological process membrane Pf05602 56457 ENSMUSG00000002981.10 Clptm1 7 0 Low Q8K3J1 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial OS=Mus musculus OX=10090 GN=Ndufs8 PE=1 SV=1" 0.058 1.278 8 1 1 1 212 24 6.21 1 1 111509.6406 132214.6563 102907.8281 1 1 1 cell organization and biogenesis;metabolic process;response to stimulus;transport membrane;mitochondrion catalytic activity;metal ion binding "Pf00037, Pf12797, Pf12837, Pf12838, Pf13183, Pf13187, Pf13237, Pf13459, Pf13484, Pf13534, Pf14697" 225887 ENSMUSG00000059734.6 Ndufs8 19 Complex I biogenesis Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 Low F6SH71 BTB/POZ domain-containing protein KCTD2 (Fragment) OS=Mus musculus OX=10090 GN=Kctd2 PE=1 SV=1 0.056 1.298 6 1 1 1 278 30.1 5.29 1 1 18312.43555 260263.8594 182731.3125 1 1 1 cell organization and biogenesis protein binding Pf02214 ENSMUSG00000016940.18 11 0 Medium P26043 Radixin OS=Mus musculus OX=10090 GN=Rdx PE=1 SV=3 0.021 1.731 2 1 1 1 583 68.5 6.2 cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane protein binding;RNA binding "Pf00373, Pf00769, Pf09379, Pf09380" 19684 ENSMUSG00000032050.17 Rdx 9 Regulation of actin cytoskeleton; MicroRNAs in cancer; Proteoglycans in cancer 0 Low A0A0G2JEY4 RIKEN cDNA 3110082I17 gene OS=Mus musculus OX=10090 GN=3110082I17Rik PE=1 SV=1 0.075 1.183 15 1 1 1 178 20 9.88 Pf10180 ENSMUSG00000053553.11 5 0 Medium O09106 Histone deacetylase 1 OS=Mus musculus OX=10090 GN=Hdac1 PE=1 SV=1 0.011 2.217 4 1 1 1 482 55 5.48 33851.36328 1 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus chromosome;cytoplasm;cytosol;nucleus catalytic activity;DNA binding;metal ion binding;protein binding Pf00850 433759 ENSMUSG00000028800.15 Hdac1 4 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Deactivation of the beta-catenin transactivating complex; Downregulation of SMAD2/3:SMAD4 transcriptional activity; Formation of the beta-catenin:TCF transactivating complex; RNA Polymerase I Transcription Initiation; SUMOylation of chromatin organization proteins; G0 and Early G1; NoRC negatively regulates rRNA expression; Regulation of PTEN gene transcription; Regulation of TP53 Activity through Acetylation; Mus musculus biological processes; Factors involved in megakaryocyte development and platelet production Epstein-Barr virus infection; Amphetamine addiction; Huntington's disease; Transcriptional misregulation in cancer; Notch signaling pathway; Thyroid hormone signaling pathway; Cell cycle; Pathways in cancer; Alcoholism; Viral carcinogenesis; Chronic myeloid leukemia; Longevity regulating pathway - multiple species 0 Medium A0A0A6YX37 Hyaluronidase OS=Mus musculus OX=10090 GN=Hyal2 PE=1 SV=1 0.03 1.519 2 1 1 1 333 38.1 8.34 cell differentiation;defense response;metabolic process;regulation of biological process;response to stimulus cell surface;membrane catalytic activity;protein binding;receptor activity Pf01630 ENSMUSG00000010047.12 9 0 Low A0A0A6YWJ7 Feline leukemia virus subgroup C receptor-related protein 1 OS=Mus musculus OX=10090 GN=Flvcr1 PE=1 SV=1 0.078 1.144 7 1 1 1 246 26.1 6.3 31729.31641 1 cell differentiation;regulation of biological process;transport membrane;mitochondrion transporter activity Pf07690 226844 ENSMUSG00000066595.9 Flvcr1; Mfsd7b 1 0 Medium Q9WVJ2 26S proteasome non-ATPase regulatory subunit 13 OS=Mus musculus OX=10090 GN=Psmd13 PE=1 SV=1 0.026 1.572 3 1 1 1 376 42.8 5.71 2396.932617 1 cell organization and biogenesis;metabolic process cytosol;membrane;nucleus;proteasome catalytic activity;protein binding;structural molecule activity Pf01399 23997 ENSMUSG00000025487.15 Psmd13 7 The role of GTSE1 in G2/M progression after G2 checkpoint; CDT1 association with the CDC6:ORC:origin complex; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Degradation of beta-catenin by the destruction complex; Autodegradation of the E3 ubiquitin ligase COP1; UCH proteinases; MAPK6/MAPK4 signaling; SCF-beta-TrCP mediated degradation of Emi1; CDK-mediated phosphorylation and removal of Cdc6; Separation of Sister Chromatids; SCF(Skp2)-mediated degradation of p27/p21; GLI3 is processed to GLI3R by the proteasome; Ub-specific processing proteases; Regulation of ornithine decarboxylase (ODC); Activation of NF-kappaB in B cells; Degradation of GLI1 by the proteasome; FCERI mediated NF-kB activation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Hedgehog ligand biogenesis; Neutrophil degranulation; Downstream TCR signaling; Autodegradation of Cdh1 by Cdh1:APC/C; Regulation of RAS by GAPs; Interleukin-1 family signaling; Asymmetric localization of PCP proteins; G2/M Checkpoints; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Regulation of PTEN stability and activity; Ubiquitin-dependent degradation of Cyclin D1; NIK-->noncanonical NF-kB signaling; Removal of licensing factors from origins; M/G1 Transition; Interleukin-20 family signaling; Regulation of RUNX2 expression and activity; Cross-presentation of soluble exogenous antigens (endosomes); ABC-family proteins mediated transport; APC/C:Cdc20 mediated degradation of Securin; Regulation of DNA replication; Dectin-1 mediated noncanonical NF-kB signaling; Antigen processing: Ubiquitination & Proteasome degradation; Orc1 removal from chromatin; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of RUNX3 expression and activity; Hedgehog 'on' state; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Degradation of DVL; Degradation of AXIN Proteasome; Epstein-Barr virus infection 0 Low Q3UNH4 G protein-regulated inducer of neurite outgrowth 1 OS=Mus musculus OX=10090 GN=Gprin1 PE=1 SV=2 0.076 1.148 1 1 1 1 932 95.4 7.93 cell organization and biogenesis membrane protein binding Pf15235 26913 ENSMUSG00000069227.4 Gprin1 13 0 Low F6YD01 Pumilio homolog 2 (Fragment) OS=Mus musculus OX=10090 GN=Pum2 PE=1 SV=1 0.062 1.256 3 1 1 1 222 25.3 7.5 RNA binding Pf00806 ENSMUSG00000020594.14 12 0 Medium Q99LT0 Protein dpy-30 homolog OS=Mus musculus OX=10090 GN=Dpy30 PE=1 SV=1 0.02 1.699 9 1 1 1 99 11.2 4.88 4396.084961 1 cell organization and biogenesis;metabolic process;regulation of biological process;transport Golgi;nucleus catalytic activity;protein binding Pf05186 66310 ENSMUSG00000024067.13 Dpy30 17 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; PKMTs methylate histone lysines 0 Low D6RCI7 mRNA turnover protein 4 homolog (Fragment) OS=Mus musculus OX=10090 GN=Mrto4 PE=1 SV=2 0.059 1.273 13 1 1 1 61 7.2 10.76 1886.115234 1 Pf00466 ENSMUSG00000028741.13 4 0 Low Q91WN1 DnaJ homolog subfamily C member 9 OS=Mus musculus OX=10090 GN=Dnajc9 PE=1 SV=2 0.053 1.323 5 1 1 1 259 30 5.94 5848.624023 1 regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;nucleus protein binding Pf00226 108671 ENSMUSG00000021811.6 Dnajc9 14 0 High P55258 Ras-related protein Rab-8A OS=Mus musculus OX=10090 GN=Rab8a PE=1 SV=2 0.004 3.458 6 1 1 1 207 23.7 9.07 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;endosome;Golgi;membrane catalytic activity;nucleotide binding;protein binding "Pf00025, Pf00071, Pf08477" 17274 ENSMUSG00000003037.16 Rab8a 8 Anchoring of the basal body to the plasma membrane; VxPx cargo-targeting to cilium; TBC/RABGAPs; Regulation of PLK1 Activity at G2/M Transition; RAB geranylgeranylation Endocytosis; Pancreatic secretion; AMPK signaling pathway 0 Low D6RFR9 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 OS=Mus musculus OX=10090 GN=Alkbh6 PE=1 SV=1 0.055 1.314 11 1 1 1 112 12.7 6.55 Pf13532 ENSMUSG00000042831.13 7 0 High P19783 "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Mus musculus OX=10090 GN=Cox4i1 PE=1 SV=2" 0.007 2.245 7 1 1 1 169 19.5 9.23 7639.520508 25253.14258 25102.58203 20062.68359 1 1 1 1 metabolic process;response to stimulus;transport membrane;mitochondrion;nucleus catalytic activity;transporter activity Pf02936 12857 ENSMUSG00000031818.12 Cox4i1 8 Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 High A0A3Q4EH93 Cytosolic Fe-S cluster assembly factor NUBP2 OS=Mus musculus OX=10090 GN=Nubp2 PE=1 SV=1 0.004 2.707 6 1 1 1 211 23 5.81 0 Medium Q3UK02 "39S ribosomal protein L9, mitochondrial OS=Mus musculus OX=10090 GN=Mrpl9 PE=1 SV=1" 0.049 1.344 4 1 1 1 268 30.8 10.08 1 1 41366.125 76582.24219 63791.04297 1 1 1 metabolic process mitochondrion;ribosome RNA binding;structural molecule activity Pf01281 78523 ENSMUSG00000028140.13 Mrpl9 3 0 Medium O88552 Claudin-2 OS=Mus musculus OX=10090 GN=Cldn2 PE=1 SV=1 0.014 1.88 7 1 1 1 230 24.5 7.93 membrane protein binding;structural molecule activity Pf00822 12738 ENSMUSG00000047230.6 Cldn2 X Leukocyte transendothelial migration; Cell adhesion molecules (CAMs); Hepatitis C; Tight junction 0 Medium A0A140LHI4 Potassium voltage-gated channel subfamily C member 3 OS=Mus musculus OX=10090 GN=Kcnc3 PE=1 SV=1 0.037 1.438 1 1 1 1 730 77.8 6.52 cell organization and biogenesis;regulation of biological process;transport cytoplasm;cytoskeleton;membrane protein binding;transporter activity "Pf00520, Pf02214, Pf07885" 16504 ENSMUSG00000062785.14 Kcnc3 7 Voltage gated Potassium channels 0 Medium Q3U821 WD repeat-containing protein 75 OS=Mus musculus OX=10090 GN=Wdr75 PE=1 SV=1 0.02 1.691 3 1 1 1 830 94 6.18 metabolic process;regulation of biological process nucleus protein binding;RNA binding Pf00400 73674 ENSMUSG00000025995.16 Wdr75 1 Major pathway of rRNA processing in the nucleolus and cytosol Ribosome biogenesis in eukaryotes 0 Medium Q7TMF2 3'-5' exoribonuclease 1 OS=Mus musculus OX=10090 GN=Eri1 PE=1 SV=2 0.026 1.569 2 1 1 1 345 39.5 8.31 metabolic process;regulation of biological process cytoplasm;nucleus catalytic activity;metal ion binding;protein binding;RNA binding Pf00929 67276 Eri1 8 0 Low Q9DCM0 "Persulfide dioxygenase ETHE1, mitochondrial OS=Mus musculus OX=10090 GN=Ethe1 PE=1 SV=2" 0.058 1.282 5 1 1 1 254 27.7 7.23 6210.096191 1 metabolic process cytoplasm;mitochondrion;nucleus;organelle lumen catalytic activity;metal ion binding "Pf00753, Pf12706" 66071 ENSMUSG00000064254.6 Ethe1 7 Sulfide oxidation to sulfate Sulfur metabolism 0 High E9PX65 Tyrosine--tRNA ligase OS=Mus musculus OX=10090 GN=Yars2 PE=1 SV=1 0.007 2.281 3 1 1 1 349 38.6 9.55 metabolic process cytoplasm catalytic activity;nucleotide binding Pf00579 ENSMUSG00000022792.16 16 0 High P07309 Transthyretin OS=Mus musculus OX=10090 GN=Ttr PE=1 SV=1 0.007 2.257 7 1 1 1 147 15.8 6.16 metabolic process;regulation of biological process;transport extracellular protein binding Pf00576 22139 ENSMUSG00000061808.3 Ttr 18 The canonical retinoid cycle in rods (twilight vision); Neutrophil degranulation; Non-integrin membrane-ECM interactions; Signaling by GPCR; Retinoid metabolism and transport Thyroid hormone synthesis 0 High A0A1W2P729 Protein canopy homolog 2 (Fragment) OS=Mus musculus OX=10090 GN=Cnpy2 PE=1 SV=1 0.002 4.557 12 1 1 1 136 15.3 5.58 6204.484375 15934.21875 1 1 Pf11938 ENSMUSG00000025381.3 10 0 High F6V6T4 Transmembrane emp24 domain-containing protein 2 (Fragment) OS=Mus musculus OX=10090 GN=Tmed2 PE=1 SV=1 0.005 3.22 5 1 1 1 176 20 9.07 regulation of biological process;transport membrane Pf01105 ENSMUSG00000029390.13 5 0 Medium Q8BK06 F-box only protein 9 OS=Mus musculus OX=10090 GN=Fbxo9 PE=1 SV=1 0.014 1.903 3 1 1 1 437 50.7 6.84 8908.107422 1 cell differentiation;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm catalytic activity;protein binding "Pf00646, Pf04212, Pf12937" 71538 ENSMUSG00000001366.14 Fbxo9 9 Neddylation; Antigen processing: Ubiquitination & Proteasome degradation 0 Medium A0A1L1SSF2 ADP-dependent glucokinase OS=Mus musculus OX=10090 GN=Adpgk PE=1 SV=1 0.017 1.837 3 1 1 1 496 53.9 5.62 metabolic process endoplasmic reticulum;extracellular;membrane catalytic activity;metal ion binding Pf04587 72141 ENSMUSG00000025236.11 Adpgk 9 Glycolysis Metabolic pathways; Glycolysis / Gluconeogenesis; Carbon metabolism 0 Medium Q3UUY6 Prominin-2 OS=Mus musculus OX=10090 GN=Prom2 PE=1 SV=1 0.027 1.561 2 1 1 1 835 93.1 7.18 311729.875 87960.45313 103945.5625 76078.76563 1 1 1 1 regulation of biological process cell surface;membrane Pf05478 192212 ENSMUSG00000027376.15 Prom2 2 0 Low E9QLQ9 Adenomatous polyposis coli protein OS=Mus musculus OX=10090 GN=Apc PE=1 SV=1 0.069 1.232 1 1 1 1 2808 307.3 7.65 cellular component movement;regulation of biological process;response to stimulus cytoplasm;nucleus protein binding "Pf00514, Pf05923, Pf05924, Pf05937, Pf05956, Pf11414" ENSMUSG00000005871.14 18 Beta-catenin phosphorylation cascade; Apoptotic cleavage of cellular proteins; Deactivation of the beta-catenin transactivating complex; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Ovarian tumor domain proteases 0 Medium Q61133 Glutathione S-transferase theta-2 OS=Mus musculus OX=10090 GN=Gstt2 PE=1 SV=4 0.035 1.465 3 1 1 1 244 27.6 7.55 3630.256348 1 metabolic process cytoplasm;cytosol;nucleus antioxidant activity;catalytic activity;protein binding "Pf00043, Pf02798, Pf13409, Pf13410, Pf13417" 14872 ENSMUSG00000033318.7 Gstt2 10 Glutathione conjugation Glutathione metabolism; Platinum drug resistance; Drug metabolism - cytochrome P450; Chemical carcinogenesis; Metabolism of xenobiotics by cytochrome P450 0 Medium Q6P4T2 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Mus musculus OX=10090 GN=Snrnp200 PE=1 SV=1 0.02 1.684 0 1 1 1 2136 244.4 6.06 34335.83594 1 cell differentiation;metabolic process membrane;nucleus;spliceosomal complex catalytic activity;DNA binding;nucleotide binding;protein binding;RNA binding "Pf00270, Pf00271, Pf02889, Pf04851" 320632 ENSMUSG00000003660.10 Snrnp200 2 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway Spliceosome 0 High A0A140LHY3 Mucolipin-1 (Fragment) OS=Mus musculus OX=10090 GN=Mcoln1 PE=1 SV=1 0.004 3.41 16 1 1 1 115 12.8 5.26 cell organization and biogenesis membrane ENSMUSG00000004567.16 8 0 Low Q8BHN5 RNA-binding protein 45 OS=Mus musculus OX=10090 GN=Rbm45 PE=1 SV=1 0.07 1.225 3 1 1 1 476 53.3 7.69 911037.8125 1054309 1139369.375 1 1 1 cell differentiation;development cytoplasm;nucleus RNA binding "Pf00076, Pf13893, Pf14259" 241490 ENSMUSG00000042369.8 Rbm45 2 0 Medium Q01149 Collagen alpha-2(I) chain OS=Mus musculus OX=10090 GN=Col1a2 PE=1 SV=2 0.03 1.529 1 1 1 1 1372 129.5 9.19 1 1 149899.1875 217099.4219 75184.39844 62770.55859 1 1 1 1 cell organization and biogenesis;regulation of biological process;response to stimulus endoplasmic reticulum;extracellular metal ion binding;protein binding;structural molecule activity "Pf01391, Pf01410" 12843 ENSMUSG00000029661.16 Col1a2 6 Anchoring fibril formation; ECM proteoglycans; Cell surface interactions at the vascular wall; Platelet Aggregation (Plug Formation); Integrin cell surface interactions; Collagen degradation; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; Crosslinking of collagen fibrils; Collagen chain trimerization; GP1b-IX-V activation signalling; Platelet Adhesion to exposed collagen; MET activates PTK2 signaling; GPVI-mediated activation cascade; Non-integrin membrane-ECM interactions AGE-RAGE signaling pathway in diabetic complications; Focal adhesion; Protein digestion and absorption; Platelet activation; Proteoglycans in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway; Amoebiasis 0 High D6RFQ2 Predicted gene 42957 OS=Mus musculus OX=10090 GN=Gm42957 PE=1 SV=1 0.002 3.877 3 1 1 1 366 39.8 9.22 cell organization and biogenesis protein binding Pf05648 ENSMUSG00000106447.1 3 0 High B9EJ54 Nucleoporin 205 OS=Mus musculus OX=10090 GN=Nup205 PE=1 SV=1 0.005 2.544 0 1 1 1 2008 227.3 6.34 122056.7578 1 cell organization and biogenesis membrane structural molecule activity Pf11894 70699 ENSMUSG00000038759.15 Nup205 6 Transcriptional regulation by small RNAs; SUMOylation of RNA binding proteins; snRNP Assembly; SUMOylation of chromatin organization proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of Glucokinase by Glucokinase Regulatory Protein; Transport of Mature mRNA derived from an Intron-Containing Transcript; SUMOylation of DNA damage response and repair proteins; SUMOylation of DNA replication proteins RNA transport 0 Low E9PZM4 Chromodomain-helicase-DNA-binding protein 2 OS=Mus musculus OX=10090 GN=Chd2 PE=1 SV=1 0.079 1.125 0 1 1 1 1827 210.7 8.06 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus nucleus catalytic activity;DNA binding;nucleotide binding;protein binding;RNA binding "Pf00176, Pf00271, Pf00385, Pf11496, Pf13907" 244059 ENSMUSG00000078671.11 Chd2 7 0 Medium E9QN31 Probable 28S rRNA (cytosine-C(5))-methyltransferase OS=Mus musculus OX=10090 GN=Nop2 PE=1 SV=1 0.018 1.82 2 1 1 1 794 86.9 9.19 cell organization and biogenesis;metabolic process;regulation of biological process nucleus catalytic activity;RNA binding "Pf01189, Pf12847" 110109 ENSMUSG00000038279.10 Nop2 6 0 Medium Q61087 Laminin subunit beta-3 OS=Mus musculus OX=10090 GN=Lamb3 PE=1 SV=2 0.029 1.556 1 1 1 1 1168 128.8 7.47 13243.76563 38447.28906 1 1 cell differentiation extracellular protein binding "Pf00053, Pf00055" 16780 ENSMUSG00000026639.18 Lamb3 1 Anchoring fibril formation; Laminin interactions; Degradation of the extracellular matrix; Type I hemidesmosome assembly; MET activates PTK2 signaling Focal adhesion; Toxoplasmosis; Small cell lung cancer; Pathways in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway; Amoebiasis 0 High Q9WTZ2 Membrane-bound transcription factor site-1 protease OS=Mus musculus OX=10090 GN=Mbtps1 PE=1 SV=1 0.002 5.091 1 1 1 1 1052 117.4 8.76 cell organization and biogenesis;metabolic process;regulation of biological process endoplasmic reticulum;Golgi;membrane;organelle lumen catalytic activity "Pf00082, Pf14258" 56453 ENSMUSG00000031835.16 Mbtps1 8 CREB3 factors activate genes; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Regulation of cholesterol biosynthesis by SREBP (SREBF); ATF6 (ATF6-alpha) activates chaperones Protein processing in endoplasmic reticulum 0 Medium Q9JL70 Fanconi anemia group A protein homolog OS=Mus musculus OX=10090 GN=Fanca PE=2 SV=2 0.012 2.066 1 1 1 1 1439 161.1 7.2 2018.118774 10800.64453 2887.199219 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus Pf03511 14087 ENSMUSG00000032815.16 Fanca 8 Fanconi Anemia Pathway Fanconi anemia pathway 0 Low Q3UXZ9 Lysine-specific demethylase 5A OS=Mus musculus OX=10090 GN=Kdm5a PE=1 SV=2 0.067 1.245 1 1 1 1 1690 192.1 6.39 cell organization and biogenesis;development;metabolic process;regulation of biological process nucleus catalytic activity;DNA binding;metal ion binding;protein binding "Pf00628, Pf01388, Pf02373, Pf02375, Pf02928, Pf08429" 214899 ENSMUSG00000030180.15 Kdm5a 6 HDMs demethylate histones 0 Medium Q792Z1 Trypsin 10 OS=Mus musculus OX=10090 GN=Try10 PE=1 SV=1 0.013 1.948 5 1 1 1 246 26.2 5.83 202086.2344 262542.1563 79099.49219 1 1 1 metabolic process catalytic activity Pf00089 436522 ENSMUSG00000071521.4 Try10 6 "Cobalamin (Cbl, vitamin B12) transport and metabolism; Neutrophil degranulation; Collagen degradation; Antimicrobial peptides; Activation of Matrix Metalloproteinases" Pancreatic secretion; Protein digestion and absorption; Influenza A; Neuroactive ligand-receptor interaction 0 Medium P27641 X-ray repair cross-complementing protein 5 OS=Mus musculus OX=10090 GN=Xrcc5 PE=1 SV=4 0.039 1.415 1 1 1 1 732 83 5.16 1989.867188 3048.518311 1 1 cell differentiation;cell organization and biogenesis;cell proliferation;defense response;metabolic process;regulation of biological process;response to stimulus chromosome;cytoplasm;membrane;nucleus catalytic activity;DNA binding;nucleotide binding;protein binding;RNA binding "Pf02735, Pf03730, Pf03731, Pf08785" 22596 ENSMUSG00000026187.8 Xrcc5 1 Neutrophil degranulation; Nonhomologous End-Joining (NHEJ) Non-homologous end-joining 0 High A9JEI5 Toll-interacting protein OS=Mus musculus OX=10090 GN=Tollip PE=1 SV=1 0.004 2.661 6 1 1 1 205 22.9 4.91 defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm protein binding "Pf00168, Pf02845" 54473 ENSMUSG00000025139.14 Tollip 7 0 High Q8R3Q0 Store-operated calcium entry-associated regulatory factor OS=Mus musculus OX=10090 GN=Saraf PE=1 SV=2 0.004 2.609 6 1 1 1 334 35.8 8.19 regulation of biological process;transport endoplasmic reticulum;membrane Pf06682 67887 Tmem66; Saraf 8 0 High A0A0B4J1H9 Immunoglobulin kappa variable 1-132 (Fragment) OS=Mus musculus OX=10090 GN=Igkv1-132 PE=4 SV=1 0.004 2.721 11 1 1 1 120 13.4 5.96 22379.33984 1 response to stimulus Pf07686 243423 ENSMUSG00000096580.1 Igkv1-132 6 0 Medium P09671 "Superoxide dismutase [Mn], mitochondrial OS=Mus musculus OX=10090 GN=Sod2 PE=1 SV=3" 0.023 1.631 6 1 1 1 222 24.6 8.62 20436.73828 13927.21094 1 1 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;mitochondrion;organelle lumen antioxidant activity;catalytic activity;DNA binding;metal ion binding;protein binding "Pf00081, Pf02777" 20656 ENSMUSG00000006818.4 Sod2 17 Transcriptional activation of mitochondrial biogenesis; Detoxification of Reactive Oxygen Species FoxO signaling pathway; Longevity regulating pathway; Huntington's disease; Longevity regulating pathway - multiple species; Peroxisome 0 High Q921I9 Exosome complex component RRP41 OS=Mus musculus OX=10090 GN=Exosc4 PE=1 SV=3 0.004 2.786 7 1 1 1 245 26.2 6.15 12199.98438 1 defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;nucleus protein binding;RNA binding "Pf01138, Pf03725" 109075 ENSMUSG00000034259.7 Exosc4 15 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease; Major pathway of rRNA processing in the nucleolus and cytosol; KSRP (KHSRP) binds and destabilizes mRNA RNA degradation 0 Low A0A1B0GSR9 L-lactate dehydrogenase OS=Mus musculus OX=10090 GN=Ldha PE=1 SV=1 0.053 1.317 3 1 1 1 315 34.6 8.56 17258.26172 22128.90625 1 1 metabolic process cytoplasm catalytic activity "Pf00056, Pf02866" ENSMUSG00000063229.15 7 0 Medium A0A1B0GRY3 Predicted gene 45861 OS=Mus musculus OX=10090 GN=Gm45861 PE=4 SV=1 0.011 2.111 1 1 1 1 1923 215.4 5.88 52424.89063 249028.8594 262956.375 466289.125 1 1 1 1 protein binding "Pf00023, Pf02463, Pf12001, Pf12128, Pf12796, Pf13606, Pf13637, Pf13857" ENSMUSG00000110333.1 8 0 Low Q9D8U3 Endoplasmic reticulum resident protein 27 OS=Mus musculus OX=10090 GN=Erp27 PE=1 SV=1 0.08 1.111 8 1 1 1 272 30.7 5 21781.28906 29262.21484 1 1 endoplasmic reticulum;organelle lumen Pf13848 69187 ENSMUSG00000030219.13 Erp27 6 0 High A2AEX6 Four and a half LIM domains protein 1 OS=Mus musculus OX=10090 GN=Fhl1 PE=1 SV=1 0.005 3.271 4 1 1 1 309 35.1 8.44 1 1 383902.4375 272892.1563 1 1 cell differentiation;development;regulation of biological process cytoplasm;cytosol;membrane;nucleus metal ion binding;protein binding Pf00412 14199 ENSMUSG00000023092.16 Fhl1 X 0 Low Q9JJQ0 GPI mannosyltransferase 3 OS=Mus musculus OX=10090 GN=Pigb PE=2 SV=2 0.058 1.279 2 1 1 1 542 63.1 9.23 4091.372314 3285.456299 6196.538086 1 1 1 metabolic process endoplasmic reticulum;membrane catalytic activity Pf03901 55981 ENSMUSG00000079469.10 Pigb 9 Synthesis of glycosylphosphatidylinositol (GPI) Glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Metabolic pathways 0 High K3W4L3 Prosaposin OS=Mus musculus OX=10090 GN=Psap PE=1 SV=1 0.004 2.661 2 1 1 1 556 61.3 5.24 metabolic process vacuole "Pf02199, Pf03489, Pf05184" ENSMUSG00000004207.14 10 0 Medium Q9CZ82 Mediator of RNA polymerase II transcription subunit 18 OS=Mus musculus OX=10090 GN=Med18 PE=1 SV=1 0.025 1.589 5 1 1 1 208 23.6 6.54 18738.39844 1 metabolic process;regulation of biological process nucleus catalytic activity Pf09637 67219 ENSMUSG00000066042.4 Med18 4 Mus musculus biological processes; Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes 0 Medium P70289 Receptor-type tyrosine-protein phosphatase V OS=Mus musculus OX=10090 GN=Ptprv PE=2 SV=1 0.039 1.428 0 1 1 1 1705 186.7 6.23 cell proliferation;metabolic process;regulation of biological process;response to stimulus membrane catalytic activity;protein binding "Pf00041, Pf00102, Pf00782, Pf13350, Pf14566" 13924 Ptprv 1 0 High P49312 Heterogeneous nuclear ribonucleoprotein A1 OS=Mus musculus OX=10090 GN=Hnrnpa1 PE=1 SV=2 0.005 2.968 5 1 1 1 320 34.2 9.23 9166.308594 1 metabolic process;transport cytoplasm;nucleus;spliceosomal complex DNA binding;RNA binding "Pf00076, Pf13893, Pf14259" 15382 ENSMUSG00000046434.15 Hnrnpa1 15 mRNA Splicing - Major Pathway; FGFR2 alternative splicing Spliceosome 0 High Q5F2E7 Nuclear fragile X mental retardation-interacting protein 2 OS=Mus musculus OX=10090 GN=Nufip2 PE=1 SV=1 0.002 4.134 2 1 1 1 692 75.6 8.7 cytoplasm;cytosol;membrane;nucleus;ribosome RNA binding Pf15293 68564 ENSMUSG00000037857.16 Nufip2 11 0 High O54904 "Beta-1,3-galactosyltransferase 1 OS=Mus musculus OX=10090 GN=B3galt1 PE=1 SV=2" 0.004 2.642 5 1 1 1 326 38 9.29 metabolic process Golgi;membrane catalytic activity Pf01762 26877 ENSMUSG00000034780.6 B3galt1 2 Metabolic pathways; Glycosphingolipid biosynthesis - lacto and neolacto series 0 Low P45376 Aldo-keto reductase family 1 member B1 OS=Mus musculus OX=10090 GN=Akr1b1 PE=1 SV=3 0.053 1.322 2 1 1 1 316 35.7 7.18 3160.195068 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;vacuole catalytic activity Pf00248 11677 ENSMUSG00000001642.18 Akr1b3 6 Pregnenolone biosynthesis; Fructose biosynthesis Metabolic pathways; Glycerolipid metabolism; Fructose and mannose metabolism; Pentose and glucuronate interconversions; Galactose metabolism 0 Medium A0A0R4J0B2 Phospholipase B-like OS=Mus musculus OX=10090 GN=Plbd1 PE=1 SV=1 0.013 1.991 2 1 1 1 550 63 8.87 metabolic process vacuole catalytic activity Pf04916 66857 ENSMUSG00000030214.6 Plbd1 6 Acyl chain remodelling of PI; Hydrolysis of LPC; Acyl chain remodelling of PC; Acyl chain remodelling of PE 0 High Q9DCN2 NADH-cytochrome b5 reductase 3 OS=Mus musculus OX=10090 GN=Cyb5r3 PE=1 SV=3 0.006 2.409 3 1 1 1 301 34.1 8.38 metabolic process cytoplasm;endoplasmic reticulum;membrane;mitochondrion catalytic activity;nucleotide binding;protein binding "Pf00175, Pf00970" 109754 ENSMUSG00000018042.17 Cyb5r3 15 Phase I - Functionalization of compounds; Neutrophil degranulation; Vitamin C (ascorbate) metabolism Amino sugar and nucleotide sugar metabolism 0 Medium A2AFI6 Transmembrane 9 superfamily member OS=Mus musculus OX=10090 GN=Gm364 PE=1 SV=1 0.029 1.554 2 1 1 1 671 77.2 6.48 membrane Pf02990 245423 ENSMUSG00000079584.2 Gm364 X 0 High Q8CGY8 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Mus musculus OX=10090 GN=Ogt PE=1 SV=2 0.003 3.541 1 1 1 1 1046 116.9 6.7 6454.61084 1 cell death;cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;protein binding "Pf00515, Pf04184, Pf07719, Pf13176, Pf13181, Pf13374, Pf13414, Pf13424, Pf13428, Pf13429, Pf13431, Pf13432, Pf13844, Pf14559" 108155 ENSMUSG00000034160.13 Ogt X HATs acetylate histones; UCH proteinases Insulin resistance; Other types of O-glycan biosynthesis 0 Medium G3UYV7 40S ribosomal protein S28 (Fragment) OS=Mus musculus OX=10090 GN=Rps28 PE=1 SV=1 0.04 1.408 20 1 1 1 56 6.3 9.96 metabolic process ribosome structural molecule activity Pf01200 ENSMUSG00000067288.12 17 0 High Q8BP48 Methionine aminopeptidase 1 OS=Mus musculus OX=10090 GN=Metap1 PE=1 SV=1 0.004 2.763 3 1 1 1 386 43.2 7.17 metabolic process cytoplasm catalytic activity;metal ion binding Pf00557 75624 ENSMUSG00000005813.12 Metap1 3 "Inactivation, recovery and regulation of the phototransduction cascade; Signaling by GPCR" 0 Medium Q91V41 Ras-related protein Rab-14 OS=Mus musculus OX=10090 GN=Rab14 PE=1 SV=3 0.026 1.58 14 1 1 1 215 23.9 6.21 cell organization and biogenesis;defense response;regulation of biological process;response to stimulus;transport cytosol;endoplasmic reticulum;endosome;Golgi;membrane;vacuole catalytic activity;nucleotide binding;protein binding "Pf00009, Pf00025, Pf00071, Pf04670, Pf08477" 68365 ENSMUSG00000026878.16 Rab14 2 RAB GEFs exchange GTP for GDP on RABs; Synthesis of PIPs at the plasma membrane; Neutrophil degranulation AMPK signaling pathway 0 High A0A075B5J6 "Predicted gene, 20730 OS=Mus musculus OX=10090 GN=Gm20730 PE=4 SV=7" 0.002 4.339 11 1 1 1 119 13.1 5.96 41912.96094 197739.4531 1 1 response to stimulus Pf07679 ENSMUSG00000076500.2 6 0 Medium Q8BZY3 DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b OS=Mus musculus OX=10090 GN=Ddx19b PE=1 SV=1 0.02 1.746 3 1 1 1 494 55.6 8.54 metabolic process;regulation of biological process cytoplasm;membrane;spliceosomal complex catalytic activity;nucleotide binding "Pf00270, Pf00271" 234733 ENSMUSG00000033658.16 Ddx19b 8 0 Medium P12787 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Mus musculus OX=10090 GN=Cox5a PE=1 SV=2" 0.026 1.573 5 1 1 1 146 16.1 6.54 28421.95898 89397.21094 69108.78125 55656.50781 1 1 1 1 metabolic process;transport membrane;mitochondrion catalytic activity;metal ion binding;transporter activity Pf02284 12858 ENSMUSG00000000088.7 Cox5a 9 Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 Medium Q8R1Q8 Cytoplasmic dynein 1 light intermediate chain 1 OS=Mus musculus OX=10090 GN=Dync1li1 PE=1 SV=1 0.035 1.445 2 1 1 1 523 56.6 6.42 4427.272461 1 cell division;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport chromosome;cytoplasm;cytoskeleton;endosome;membrane;vacuole catalytic activity;motor activity;nucleotide binding;protein binding;RNA binding "Pf00005, Pf05783, Pf10662" 235661 ENSMUSG00000032435.9 Dync1li1 9 COPI-mediated anterograde transport; Neutrophil degranulation; HSP90 chaperone cycle for steroid hormone receptors (SHR); Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal; Resolution of Sister Chromatid Cohesion; Separation of Sister Chromatids; COPI-independent Golgi-to-ER retrograde traffic; RHO GTPases Activate Formins; MHC class II antigen presentation Phagosome; Salmonella infection; Vasopressin-regulated water reabsorption 0 Medium A2AQH4 BCL-6 corepressor-like protein 1 OS=Mus musculus OX=10090 GN=Bcorl1 PE=2 SV=1 0.026 1.582 1 1 1 1 1781 190.4 7.78 cell organization and biogenesis;metabolic process;regulation of biological process membrane;nucleus protein binding "Pf00023, Pf12796, Pf13606, Pf13637, Pf13857" 320376 ENSMUSG00000036959.15 Bcorl1 X 0 Low D3Z7R9 Cell cycle progression protein 1 OS=Mus musculus OX=10090 GN=Ccpg1 PE=1 SV=1 0.06 1.27 2 1 1 1 778 89.1 6.06 59589.92969 1 regulation of biological process membrane protein binding 72278 ENSMUSG00000034563.16 Ccpg1 9 0 Medium Q3UXJ2 Transforming growth factor-beta-induced protein ig-h3 OS=Mus musculus OX=10090 GN=Tgfbi PE=1 SV=1 0.019 1.764 2 1 1 1 651 70.9 7.03 1 1 150569.9531 57713.66406 81001.97656 1 1 1 cell organization and biogenesis;cell proliferation extracellular protein binding "Pf02469, Pf07546" 21810 Tgfbi 13 0 Medium P23249 Putative helicase MOV-10 OS=Mus musculus OX=10090 GN=Mov10 PE=1 SV=2 0.028 1.552 1 1 1 1 1004 113.5 9.01 4022.869873 1 metabolic process;regulation of biological process cytoplasm;cytosol catalytic activity;nucleotide binding;protein binding;RNA binding "Pf13086, Pf13087, Pf13191, Pf13245, Pf13401, Pf13604" 17454 ENSMUSG00000002227.15 Mov10 3 0 Medium O55029 Coatomer subunit beta' OS=Mus musculus OX=10090 GN=Copb2 PE=1 SV=2 0.012 2.074 1 1 1 1 905 102.4 5.3 2178.851074 10731.83203 1 1 transport cytoplasm;cytosol;Golgi;membrane protein binding;structural molecule activity "Pf00400, Pf04053" 50797 ENSMUSG00000032458.6 Copb2 9 COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic 0 Medium F6WMD1 Alpha-2-macroglobulin receptor-associated protein (Fragment) OS=Mus musculus OX=10090 GN=Lrpap1 PE=1 SV=1 0.014 1.909 8 1 1 1 153 18.3 8.32 30147.32031 1 endoplasmic reticulum protein binding "Pf06400, Pf06401" ENSMUSG00000029103.16 5 0 Medium P28028 Serine/threonine-protein kinase B-raf OS=Mus musculus OX=10090 GN=Braf PE=1 SV=3 0.012 2.033 1 1 1 1 804 88.7 7.65 13091.01465 1 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding;signal transducer activity "Pf00069, Pf00130, Pf02196, Pf07714, Pf14531" 109880 ENSMUSG00000002413.15 Braf 6 CREB phosphorylation through the activation of Ras; RAF activation; Interleukin-20 family signaling; MAP2K and MAPK activation; Spry regulation of FGF signaling; Negative feedback regulation of MAPK pathway ErbB signaling pathway; FoxO signaling pathway; Acute myeloid leukemia; mTOR signaling pathway; Regulation of actin cytoskeleton; MAPK signaling pathway; Progesterone-mediated oocyte maturation; Focal adhesion; Insulin signaling pathway; Endometrial cancer; Long-term potentiation; Chemokine signaling pathway; Breast cancer; Melanoma; Non-small cell lung cancer; Dorso-ventral axis formation; Proteoglycans in cancer; Neurotrophin signaling pathway; Long-term depression; Rap1 signaling pathway; Pathways in cancer; Hepatitis C; Alcoholism; Pancreatic cancer; Thyroid cancer; cAMP signaling pathway; Vascular smooth muscle contraction; Renal cell carcinoma; Natural killer cell mediated cytotoxicity; Glioma; EGFR tyrosine kinase inhibitor resistance; Colorectal cancer; Chronic myeloid leukemia; Serotonergic synapse; Prostate cancer; Endocrine resistance; Bladder cancer 0 Medium Q9D5T0 ATPase family AAA domain-containing protein 1 OS=Mus musculus OX=10090 GN=Atad1 PE=1 SV=1 0.016 1.859 4 1 1 1 361 40.7 6.9 metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion;nucleus catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00004, Pf00910, Pf01078, Pf05496, Pf06068, Pf07724, Pf07726, Pf13173, Pf13191, Pf13207, Pf13479" 67979 ENSMUSG00000013662.5 Atad1 19 0 Medium Q6PGG6 Guanine nucleotide-binding protein-like 3-like protein OS=Mus musculus OX=10090 GN=Gnl3l PE=1 SV=1 0.04 1.403 2 1 1 1 577 65.2 8.6 regulation of biological process cytosol;membrane;nucleus catalytic activity;nucleotide binding;RNA binding "Pf01926, Pf02421" 237107 ENSMUSG00000025266.11 Gnl3l X Ribosome biogenesis in eukaryotes 0 Low Q99PA7 Mage-k1 OS=Mus musculus OX=10090 GN=4930550L24Rik PE=1 SV=1 0.06 1.27 9 1 1 1 320 35 5.14 Pf01454 75352 ENSMUSG00000046180.11 4930550L24Rik X 0 Low Q8BHC4 Dephospho-CoA kinase domain-containing protein OS=Mus musculus OX=10090 GN=Dcakd PE=1 SV=1 0.081 1.106 6 1 1 1 231 26.5 9.58 metabolic process membrane;mitochondrion catalytic activity;nucleotide binding "Pf01121, Pf13189" 68087 ENSMUSG00000020935.8 Dcakd 11 0 Medium P01819 Ig heavy chain V region MOPC 141 OS=Mus musculus OX=10090 PE=4 SV=1 0.013 1.957 8 1 1 1 144 15.7 8.43 1 1 119961.4766 1 Pf07686 0 Medium P98083 SHC-transforming protein 1 OS=Mus musculus OX=10090 GN=Shc1 PE=1 SV=3 0.02 1.684 3 1 1 1 579 62.6 6.54 cell differentiation;cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus;organelle lumen protein binding "Pf00017, Pf00640" 20416 ENSMUSG00000042626.13 Shc1 3 Signal attenuation; MET activates RAS signaling; Interleukin-15 signaling; G beta:gamma signalling through PI3Kgamma; Interleukin receptor SHC signaling; SHC1 events in EGFR signaling; SHC-mediated cascade:FGFR3; Interleukin-20 family signaling; SHC1 events in ERBB4 signaling; RAF/MAP kinase cascade; DAP12 signaling; GPVI-mediated activation cascade; SHC-mediated cascade:FGFR4; FCERI mediated MAPK activation; Tie2 Signaling; SHC1 events in ERBB2 signaling; RET signaling; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Signalling to RAS; Role of LAT2/NTAL/LAB on calcium mobilization; SHC-mediated cascade:FGFR2; FCERI mediated Ca+2 mobilization; Integrin alphaIIb beta3 signaling; SHC-mediated cascade:FGFR1; SHC-related events triggered by IGF1R ErbB signaling pathway; Phospholipase D signaling pathway; MicroRNAs in cancer; Ras signaling pathway; Prolactin signaling pathway; Focal adhesion; Insulin signaling pathway; Chemokine signaling pathway; Breast cancer; Neurotrophin signaling pathway; Alcoholism; Natural killer cell mediated cytotoxicity; Glioma; EGFR tyrosine kinase inhibitor resistance; Estrogen signaling pathway; Chronic myeloid leukemia; Endocrine resistance; Bacterial invasion of epithelial cells 0 High Q9Z0R9 Acyl-CoA 6-desaturase OS=Mus musculus OX=10090 GN=Fads2 PE=1 SV=1 0.006 2.471 3 1 1 1 444 52.4 8.82 metabolic process;transport endoplasmic reticulum;membrane catalytic activity "Pf00173, Pf00487" 56473 ENSMUSG00000024665.7 Fads2 19 alpha-linolenic acid (ALA) metabolism; Linoleic acid (LA) metabolism PPAR signaling pathway; Fatty acid metabolism; alpha-Linolenic acid metabolism; Biosynthesis of unsaturated fatty acids 0 Medium Q99J39 "Malonyl-CoA decarboxylase, mitochondrial OS=Mus musculus OX=10090 GN=Mlycd PE=1 SV=1" 0.013 2 2 1 1 1 492 54.7 8.94 15175.58594 26363.47461 4106.167969 1 1 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;mitochondrion;organelle lumen catalytic activity;protein binding Pf05292 56690 ENSMUSG00000074064.6 Mlycd 8 Beta-oxidation of very long chain fatty acids Metabolic pathways; beta-Alanine metabolism; Propanoate metabolism; AMPK signaling pathway; Peroxisome 0 Medium Q99KP6 Pre-mRNA-processing factor 19 OS=Mus musculus OX=10090 GN=Prpf19 PE=1 SV=1 0.019 1.766 2 1 1 1 504 55.2 6.61 cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane;nucleus;spliceosomal complex catalytic activity;metal ion binding;protein binding "Pf00400, Pf04564, Pf08606, Pf11789" 28000 ENSMUSG00000024735.13 Prpf19 19 mRNA Splicing - Major Pathway; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of TC-NER Pre-Incision Complex Ubiquitin mediated proteolysis; Spliceosome 0 Low A0A0G2JDK2 Glucosylceramidase OS=Mus musculus OX=10090 GN=Gba PE=1 SV=1 0.068 1.238 3 1 1 1 388 43.3 8.75 18248.98633 1 cell communication;metabolic process;regulation of biological process;response to stimulus membrane;organelle lumen;vacuole catalytic activity;protein binding Pf02055 14466 ENSMUSG00000028048.11 Gba 3 0 Medium Q3U3R4 Lipase maturation factor 1 OS=Mus musculus OX=10090 GN=Lmf1 PE=1 SV=1 0.029 1.553 3 1 1 1 574 65.8 9.29 13244.44824 1 metabolic process;regulation of biological process;transport endoplasmic reticulum;Golgi;membrane protein binding Pf06762 76483 ENSMUSG00000002279.18 Lmf1 17 Assembly of active LPL and LIPC lipase complexes 0 Medium Q9R1T2 SUMO-activating enzyme subunit 1 OS=Mus musculus OX=10090 GN=Sae1 PE=1 SV=1 0.02 1.687 6 1 1 1 350 38.6 5.36 22903.44141 18179.72461 1 1 metabolic process cytoplasm;nucleus catalytic activity;protein binding Pf00899 56459 ENSMUSG00000052833.9 Sae1 7 "SUMO is transferred from E1 to E2 (UBE2I, UBC9); SUMO is conjugated to E1 (UBA2:SAE1)" Ubiquitin mediated proteolysis 0 High P17918 Proliferating cell nuclear antigen OS=Mus musculus OX=10090 GN=Pcna PE=1 SV=2 0.005 3.046 6 1 1 1 261 28.8 4.77 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus nucleus catalytic activity;DNA binding;enzyme regulator activity;protein binding "Pf00705, Pf02747" 18538 ENSMUSG00000027342.14 Pcna 2 Termination of translesion DNA synthesis; Polymerase switching on the C-strand of the telomere; Translesion synthesis by POLI; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion synthesis by POLK; Gap-filling DNA repair synthesis and ligation in TC-NER; Polymerase switching; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Removal of the Flap Intermediate from the C-strand; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; PCNA-Dependent Long Patch Base Excision Repair; Recognition of DNA damage by PCNA-containing replication complex; Dual incision in TC-NER; Translesion synthesis by REV1; HDR through Homologous Recombination (HRR); SUMOylation of DNA replication proteins DNA replication; Hepatitis B; HTLV-I infection; Nucleotide excision repair; Cell cycle; Base excision repair; Mismatch repair 0 High O88531 Palmitoyl-protein thioesterase 1 OS=Mus musculus OX=10090 GN=Ppt1 PE=1 SV=2 0.005 2.981 5 1 1 1 306 34.5 8 59878.95703 11963.12793 1 1 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytosol;extracellular;Golgi;membrane;nucleus;vacuole catalytic activity;protein binding Pf02089 19063 ENSMUSG00000028657.14 Ppt1 4 Fatty acyl-CoA biosynthesis Fatty acid metabolism; Metabolic pathways; Lysosome; Fatty acid elongation 0 Low Q80SY6 Adenosine deaminase-like protein OS=Mus musculus OX=10090 GN=Adal PE=2 SV=1 0.073 1.198 4 1 1 1 360 41 6.35 metabolic process cytosol catalytic activity;metal ion binding Pf00962 75894 ENSMUSG00000027259.15 Adal 2 Abacavir metabolism; Purine salvage 0 Medium A0A140LI05 Mucin 16 (Fragment) OS=Mus musculus OX=10090 GN=Muc16 PE=4 SV=1 0.049 1.339 0 1 1 1 2566 285.9 6.86 regulation of biological process membrane Pf01390 ENSMUSG00000109564.1 9 Termination of O-glycan biosynthesis 0 Low Q8BKC5 Importin-5 OS=Mus musculus OX=10090 GN=Ipo5 PE=1 SV=3 0.082 1.096 1 1 1 1 1097 123.5 4.93 regulation of biological process;response to stimulus;transport cytoplasm;membrane;nucleus protein binding;RNA binding;transporter activity "Pf02985, Pf12755, Pf13513, Pf13646" 70572 ENSMUSG00000030662.9 Ipo5 14 0 Low E9PUC6 Alpha-1-antitrypsin 1-6 OS=Mus musculus OX=10090 GN=Serpina1f PE=3 SV=1 0.068 1.235 3 1 1 1 356 40.2 8.22 regulation of biological process extracellular enzyme regulator activity Pf00079 68348 ENSMUSG00000021081.12 Serpina1f 12 0 Low G3X9Y6 "Aldo-keto reductase family 1, member C19 OS=Mus musculus OX=10090 GN=Akr1c19 PE=1 SV=1" 0.081 1.099 6 1 1 1 323 37 7.23 11544.5791 14183.0293 9756.733398 1 1 1 metabolic process catalytic activity Pf00248 432720 ENSMUSG00000071551.12 Akr1c19 13 RA biosynthesis pathway; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; Signaling by GPCR; Retinoid metabolism and transport; Synthesis of bile acids and bile salts via 24-hydroxycholesterol; Synthesis of bile acids and bile salts via 27-hydroxycholesterol; Synthesis of Prostaglandins (PG) and Thromboxanes (TX) 0 Medium Q99LP6 "GrpE protein homolog 1, mitochondrial OS=Mus musculus OX=10090 GN=Grpel1 PE=1 SV=1" 0.011 2.21 5 1 1 1 217 24.3 8.38 142678.6094 1 metabolic process;regulation of biological process;transport mitochondrion;nucleus;organelle lumen enzyme regulator activity;nucleotide binding;protein binding Pf01025 17713 ENSMUSG00000029198.3 Grpel1 5 0 Low H3BJ51 "All-trans-retinol 13,14-reductase OS=Mus musculus OX=10090 GN=Retsat PE=1 SV=1" 0.059 1.273 4 1 1 1 548 61.1 9.07 metabolic process membrane catalytic activity ENSMUSG00000056666.13 6 0 Medium P58710 L-gulonolactone oxidase OS=Mus musculus OX=10090 GN=Gulo PE=1 SV=3 0.021 1.733 2 1 1 1 440 50.4 8.24 metabolic process endoplasmic reticulum;membrane catalytic activity;nucleotide binding "Pf01565, Pf04030" 268756 ENSMUSG00000034450.7 Gulo 14 Metabolic pathways; Ascorbate and aldarate metabolism 0 High F8VPM7 ELKS/Rab6-interacting/CAST family member 1 OS=Mus musculus OX=10090 GN=Erc1 PE=1 SV=1 0.005 3.132 1 1 1 1 1120 128.3 5.91 8732.15332 1 metabolic process;regulation of biological process;transport cytoplasm;endoplasmic reticulum;Golgi;membrane protein binding "Pf04156, Pf05529, Pf05557, Pf05622, Pf09457, Pf09726, Pf10174, Pf12128, Pf13166" 111173 ENSMUSG00000030172.15 Erc1 6 0 Medium Q921V5 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Mus musculus OX=10090 GN=Mgat2 PE=1 SV=1" 0.026 1.568 3 1 1 1 442 51 8.59 48847.88281 21029.39648 35209.50781 1 1 1 metabolic process Golgi;membrane catalytic activity Pf05060 217664 ENSMUSG00000043998.10 Mgat2 12 Reactions specific to the complex N-glycan synthesis pathway Metabolic pathways; N-Glycan biosynthesis 0 Medium A0A494BAK4 Endoplasmic reticulum-Golgi intermediate compartment protein 1 OS=Mus musculus OX=10090 GN=Ergic1 PE=1 SV=1 0.047 1.356 4 1 1 1 247 27.7 7.61 3774.669189 1 0 Low A0A140LHJ6 Oxygen-regulated protein 1 OS=Mus musculus OX=10090 GN=Rp1 PE=1 SV=1 0.053 1.328 1 1 1 1 1371 153.2 8.09 cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytoskeleton protein binding "Pf01477, Pf03607" 19888 ENSMUSG00000025900.12 Rp1 1 0 Medium Q9D023 Mitochondrial pyruvate carrier 2 OS=Mus musculus OX=10090 GN=Mpc2 PE=1 SV=1 0.011 2.149 10 1 1 1 127 14.3 10.61 47306.62109 133919.25 1 1 regulation of biological process;transport membrane;mitochondrion;nucleus transporter activity Pf03650 70456 ENSMUSG00000026568.6 Mpc2 1 0 Medium Q9WTQ8 Mitochondrial import inner membrane translocase subunit Tim23 OS=Mus musculus OX=10090 GN=Timm23 PE=1 SV=1 0.024 1.614 5 1 1 1 209 22 9.13 transport membrane;mitochondrion protein binding;transporter activity Pf02466 53600 Timm23 14 0 High O35604 NPC intracellular cholesterol transporter 1 OS=Mus musculus OX=10090 GN=Npc1 PE=1 SV=2 0.004 3.478 1 1 1 1 1277 142.8 5.71 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport endoplasmic reticulum;endosome;extracellular;Golgi;membrane;vacuole protein binding;transporter activity "Pf00873, Pf02460, Pf03176, Pf12349" 18145 ENSMUSG00000024413.13 Npc1 18 LDL clearance Lysosome 0 Medium P62835 Ras-related protein Rap-1A OS=Mus musculus OX=10090 GN=Rap1a PE=1 SV=1 0.014 1.889 8 1 1 1 184 21 6.67 9541.490234 1 cellular homeostasis;regulation of biological process;response to stimulus;transport cytoplasm;endosome;membrane catalytic activity;nucleotide binding;protein binding;transporter activity "Pf00009, Pf00071, Pf08477" 109905 ENSMUSG00000068798.10 Rap1a 3 Neutrophil degranulation; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Rap1 signalling; p130Cas linkage to MAPK signaling for integrins; ARMS-mediated activation; GRB2:SOS provides linkage to MAPK signaling for Integrins ; MET activates RAP1 and RAC1 Leukocyte transendothelial migration; MAPK signaling pathway; Pancreatic secretion; Ras signaling pathway; Focal adhesion; Long-term potentiation; Chemokine signaling pathway; Platelet activation; Neurotrophin signaling pathway; Rap1 signaling pathway; cAMP signaling pathway; Renal cell carcinoma 0 Medium A0A0N4SVT1 Probable ATP-dependent RNA helicase DDX47 (Fragment) OS=Mus musculus OX=10090 GN=Ddx47 PE=1 SV=1 0.018 1.802 3 1 1 1 380 42.3 8.19 catalytic activity;nucleotide binding "Pf00270, Pf00271" ENSMUSG00000030204.10 6 0 Medium P27546 Microtubule-associated protein 4 OS=Mus musculus OX=10090 GN=Map4 PE=1 SV=3 0.035 1.461 2 1 1 1 1125 117.4 4.98 cell division;cell organization and biogenesis;cellular component movement;regulation of biological process cytoplasm;cytoskeleton protein binding;RNA binding Pf00418 17758 ENSMUSG00000032479.15 Map4; Mtap4 9 0 Low Q7TPD1 F-box only protein 11 OS=Mus musculus OX=10090 GN=Fbxo11 PE=1 SV=3 0.064 1.248 1 1 1 1 930 103.7 7.05 23666.66602 8770.535156 7326.937012 1 1 1 metabolic process chromosome;cytoplasm;cytosol;nucleus catalytic activity;metal ion binding;protein binding "Pf00646, Pf02207, Pf05048, Pf12937, Pf13229" 225055 ENSMUSG00000005371.14 Fbxo11 17 Neddylation; Antigen processing: Ubiquitination & Proteasome degradation 0 Medium Q8BI84 Transport and Golgi organization protein 1 homolog OS=Mus musculus OX=10090 GN=Mia3 PE=1 SV=2 0.016 1.855 1 1 1 1 1930 213.5 4.75 cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus;transport endoplasmic reticulum;membrane protein binding;transporter activity "Pf02463, Pf05483, Pf05557, Pf05622, Pf06409, Pf07653, Pf10174, Pf11559, Pf13166, Pf13851" 338366 Mia3 1 0 High Q8BGD9 Eukaryotic translation initiation factor 4B OS=Mus musculus OX=10090 GN=Eif4b PE=1 SV=1 0.005 2.537 3 1 1 1 611 68.8 5.67 31203.25781 1 cell organization and biogenesis;metabolic process RNA binding "Pf00076, Pf14259" 75705 ENSMUSG00000058655.8 Eif4b 15 L13a-mediated translational silencing of Ceruloplasmin expression; mTORC1-mediated signalling; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Deadenylation of mRNA mTOR signaling pathway; Proteoglycans in cancer; PI3K-Akt signaling pathway; RNA transport 0 Medium Q8BFW6 Ectonucleoside triphosphate diphosphohydrolase 3 OS=Mus musculus OX=10090 GN=Entpd3 PE=1 SV=1 0.021 1.718 2 1 1 1 529 58.9 6.15 metabolic process membrane catalytic activity Pf01150 215446 ENSMUSG00000041608.8 Entpd3 9 Phosphate bond hydrolysis by NTPDase proteins Epstein-Barr virus infection; Purine metabolism; Pyrimidine metabolism 0 Medium A2AGH8 Mediator of RNA polymerase II transcription subunit 12 OS=Mus musculus OX=10090 GN=Med12 PE=1 SV=1 0.011 2.18 1 1 1 1 2157 240.7 7.17 metabolic process;regulation of biological process;response to stimulus membrane;nucleus catalytic activity;DNA binding;protein binding;receptor activity "Pf09497, Pf09606, Pf12144, Pf12145" 59024 ENSMUSG00000079487.11 Med12 X 0 High Q8BIA4 F-box/WD repeat-containing protein 8 OS=Mus musculus OX=10090 GN=Fbxw8 PE=1 SV=2 0.004 2.646 2 1 1 1 598 67.9 6.16 cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process cytoplasm;cytosol;Golgi catalytic activity;protein binding "Pf00646, Pf12937" 231672 ENSMUSG00000032867.8 Fbxw8 5 Neddylation; Antigen processing: Ubiquitination & Proteasome degradation Ubiquitin mediated proteolysis 0 High A2AWT7 Nucleolar transcription factor 1 OS=Mus musculus OX=10090 GN=Ubtf PE=1 SV=1 0.004 2.581 2 1 1 1 752 88.3 9.89 metabolic process;regulation of biological process nucleus DNA binding;protein binding;RNA binding "Pf00505, Pf09011, Pf14887" 21429 ENSMUSG00000020923.17 Ubtf 11 RNA Polymerase I Promoter Escape; RNA Polymerase I Promoter Opening; RNA Polymerase I Chain Elongation; RNA Polymerase I Transcription Termination; RNA Polymerase I Transcription Initiation 0 Medium P97376 Protein FRG1 OS=Mus musculus OX=10090 GN=Frg1 PE=1 SV=2 0.018 1.819 5 1 1 1 258 29.1 8.92 metabolic process cytoplasm;nucleus;spliceosomal complex protein binding;RNA binding "Pf06229, Pf06268" 14300 ENSMUSG00000031590.8 Frg1 8 0 High Q64339 Ubiquitin-like protein ISG15 OS=Mus musculus OX=10090 GN=Isg15 PE=1 SV=4 0.004 2.591 6 1 1 1 161 17.9 7.9 14650.96777 12770.1123 30498.10938 1 1 1 defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;extracellular protein binding "Pf00240, Pf11976" 100038882 ENSMUSG00000035692.6 Isg15 4 Termination of translesion DNA synthesis; ISG15 antiviral mechanism RIG-I-like receptor signaling pathway 0 Medium A0A0R4J1N9 "Transcription factor A, mitochondrial OS=Mus musculus OX=10090 GN=Tfam PE=1 SV=1" 0.018 1.816 5 1 1 1 199 23.4 9.72 61732.62891 121345.1484 44079.50781 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process mitochondrion;nucleus DNA binding;protein binding;RNA binding "Pf00505, Pf09011" 21780 ENSMUSG00000003923.14 Tfam 10 0 Low Q80W93 Hydrocephalus-inducing protein OS=Mus musculus OX=10090 GN=Hydin PE=1 SV=2 0.083 1.061 1 1 1 1 5154 581.2 6.38 cellular component movement;development Pf00635 244653 ENSMUSG00000059854.8 Hydin 8 0 Low P33587 Vitamin K-dependent protein C OS=Mus musculus OX=10090 GN=Proc PE=1 SV=2 0.06 1.27 4 1 1 1 460 51.8 6.35 coagulation;metabolic process;regulation of biological process endoplasmic reticulum;extracellular;Golgi catalytic activity;metal ion binding;protein binding "Pf00008, Pf00089, Pf00594, Pf13365, Pf14670" 19123 ENSMUSG00000024386.8 Proc 18 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Removal of aminoterminal propeptides from gamma-carboxylated proteins; Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus; Intrinsic Pathway of Fibrin Clot Formation; Gamma-carboxylation of protein precursors; Cell surface interactions at the vascular wall; Post-translational protein phosphorylation; Common Pathway of Fibrin Clot Formation Complement and coagulation cascades 0 High A0A1W2P7C7 Plasma membrane calcium-transporting ATPase 1 (Fragment) OS=Mus musculus OX=10090 GN=Atp2b1 PE=1 SV=1 0.005 2.481 3 1 1 1 430 46.9 5.35 transport membrane catalytic activity;nucleotide binding;transporter activity "Pf00122, Pf00690" ENSMUSG00000019943.10 10 0 High Q62189 U1 small nuclear ribonucleoprotein A OS=Mus musculus OX=10090 GN=Snrpa PE=1 SV=3 0.007 2.285 10 1 1 1 287 31.8 9.8 metabolic process nucleus;spliceosomal complex RNA binding "Pf00076, Pf13893, Pf14259" 53607 ENSMUSG00000061479.15 Snrpa 7 mRNA Splicing - Major Pathway Spliceosome 0 Medium Q9R013 Cathepsin F OS=Mus musculus OX=10090 GN=Ctsf PE=1 SV=1 0.011 2.2 3 1 1 1 462 51.6 6.55 metabolic process vacuole catalytic activity "Pf00112, Pf08246" 56464 ENSMUSG00000083282.2 Ctsf 19 MHC class II antigen presentation Lysosome; Apoptosis 0 Medium F6VAN0 Cyclic AMP-dependent transcription factor ATF-6 alpha OS=Mus musculus OX=10090 GN=Atf6 PE=1 SV=2 0.03 1.531 1 1 1 1 656 72.6 7.77 3928.405518 4626.737305 1 1 metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;Golgi;membrane;nucleus DNA binding;protein binding "Pf00170, Pf03131, Pf06156, Pf07716, Pf09726" 226641 ENSMUSG00000026663.6 Atf6 1 ATF6 (ATF6-alpha) activates chaperones Alzheimer's disease; Protein processing in endoplasmic reticulum 0 Medium B2RSU6 Cingulin-like 1 OS=Mus musculus OX=10090 GN=Cgnl1 PE=1 SV=1 0.014 1.928 1 1 1 1 1297 148.1 5.77 3618.946045 5042.763672 1 1 cell differentiation;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;Golgi catalytic activity;motor activity;protein binding;structural molecule activity;transporter activity "Pf00038, Pf00261, Pf00769, Pf01496, Pf01576, Pf02463, Pf03961, Pf03962, Pf04094, Pf04111, Pf04156, Pf05262, Pf05483, Pf05557, Pf05622, Pf05667, Pf05701, Pf05911, Pf06008, Pf06160, Pf06548, Pf06785, Pf06810, Pf07111, Pf07888, Pf07946, Pf09726, Pf09730, Pf10174, Pf12128, Pf13166, Pf13514, Pf13654, Pf13851, Pf13863, Pf13868, Pf15070, Pf15450, Pf15619" 68178 ENSMUSG00000032232.14 Cgnl1 9 0 High Q91VK4 Integral membrane protein 2C OS=Mus musculus OX=10090 GN=Itm2c PE=1 SV=2 0.004 2.801 4 1 1 1 269 30.5 8.59 cell differentiation;regulation of biological process Golgi;membrane;vacuole nucleotide binding Pf04089 64294 ENSMUSG00000026223.15 Itm2c 1 0 Medium A0A1B0GRE0 Ras association domain-containing protein 7 OS=Mus musculus OX=10090 GN=Rassf7 PE=1 SV=1 0.044 1.375 2 1 1 1 383 41.6 5.49 regulation of biological process;response to stimulus Pf00788 ENSMUSG00000038618.12 7 0 High P06797 Cathepsin L1 OS=Mus musculus OX=10090 GN=Ctsl PE=1 SV=2 0.004 2.649 6 1 1 1 334 37.5 6.83 cell communication;cell death;cell differentiation;metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus;vacuole catalytic activity;protein binding "Pf00112, Pf08246" 13039 ENSMUSG00000021477.8 Ctsl 13 MHC class II antigen presentation; RUNX1 regulates transcription of genes involved in differentiation of keratinocytes; Activation of Matrix Metalloproteinases Rheumatoid arthritis; Lysosome; Phagosome; Proteoglycans in cancer; Antigen processing and presentation; Apoptosis 0 Low A0A0J9YVH6 RIKEN cDNA 1520401A03 gene OS=Mus musculus OX=10090 GN=1520401A03Rik PE=4 SV=1 0.075 1.182 4 1 1 1 598 59.7 9.99 320309 ENSMUSG00000043747.12 1520401A03Rik 17 0 Medium Q8R050 Eukaryotic peptide chain release factor GTP-binding subunit ERF3A OS=Mus musculus OX=10090 GN=Gspt1 PE=1 SV=2 0.05 1.334 1 1 1 1 636 68.6 5.21 1629.769287 4826.432617 1 1 cell organization and biogenesis;metabolic process cytosol catalytic activity;nucleotide binding;RNA binding "Pf00009, Pf03143, Pf03144, Pf07145" 14852 ENSMUSG00000062203.14 Gspt1 16 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination mRNA surveillance pathway 0 Medium A0A571BEG0 Maestro heat-like repeat family member 5 OS=Mus musculus OX=10090 GN=Mroh5 PE=4 SV=1 0.012 2.093 1 1 1 1 1293 146.8 7.42 0 Medium A0A140T8S0 Multiple epidermal growth factor-like domains protein 10 (Fragment) OS=Mus musculus OX=10090 GN=Megf10 PE=1 SV=2 0.029 1.545 1 1 1 1 1061 113.8 7.2 cell death;cell differentiation;cell organization and biogenesis;cell proliferation;cellular component movement membrane protein binding Pf07546 ENSMUSG00000024593.15 18 0 Low Q9CRA9 FGFR1 oncogene partner 2 homolog OS=Mus musculus OX=10090 GN=Fgfr1op2 PE=1 SV=1 0.073 1.209 5 1 1 1 253 29.4 5.83 Met-loss+Acetyl [N-Term] response to stimulus cytoplasm protein binding "Pf05769, Pf11262" 67529 ENSMUSG00000040242.14 Fgfr1op2 6 0 Medium Q8VCA6 Transmembrane protein 161A OS=Mus musculus OX=10090 GN=Tmem161a PE=2 SV=1 0.031 1.487 2 1 1 1 480 54 8.38 regulation of biological process;response to stimulus membrane Pf10268 234371 ENSMUSG00000002342.17 Tmem161a 8 0 Medium Q9JJN5 Carboxypeptidase N catalytic chain OS=Mus musculus OX=10090 GN=Cpn1 PE=1 SV=1 0.033 1.477 4 1 1 1 457 51.8 8.28 metabolic process;response to stimulus extracellular;Golgi catalytic activity;metal ion binding "Pf00246, Pf13620, Pf13715" 93721 ENSMUSG00000025196.4 Cpn1 19 Regulation of Complement cascade 0 Medium Q3TWZ5 Thioredoxin domain-containing protein 11 OS=Mus musculus OX=10090 GN=Txndc11 PE=1 SV=1 0.02 1.735 2 1 1 1 639 70.4 7.31 1599.233398 12863.47852 1 1 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;membrane catalytic activity "Pf00085, Pf13905" 106200 ENSMUSG00000022498.16 Txndc11 16 0 Low A0A2I3BR95 Kinase suppressor of Ras 1 OS=Mus musculus OX=10090 GN=Ksr1 PE=1 SV=1 0.059 1.272 1 1 1 1 818 91.3 8.21 193239.6875 59053.35547 64864.51953 1 1 1 0 Medium A0A2I3BR17 Spermatogenesis-associated protein 3 OS=Mus musculus OX=10090 GN=Spata3 PE=4 SV=1 0.013 2 3 1 1 1 333 36.8 8.9 12297.01953 1 0 High Q91XU0 ATPase WRNIP1 OS=Mus musculus OX=10090 GN=Wrnip1 PE=1 SV=2 0.007 2.334 2 1 1 1 660 71.7 6.18 5126.606445 1 metabolic process;regulation of biological process;response to stimulus membrane;nucleus catalytic activity;DNA binding;metal ion binding;nucleotide binding;protein binding;RNA binding "Pf00004, Pf00006, Pf00308, Pf00910, Pf03215, Pf04851, Pf05496, Pf07724, Pf07728, Pf12002, Pf13173, Pf13177, Pf13191, Pf13401" 78903 ENSMUSG00000021400.6 Wrnip1 13 0 Medium Q9JKC8 AP-3 complex subunit mu-1 OS=Mus musculus OX=10090 GN=Ap3m1 PE=1 SV=1 0.047 1.348 3 1 1 1 418 46.9 6.93 5074.957031 1 cellular component movement;transport Golgi;membrane protein binding "Pf00928, Pf01217" 55946 ENSMUSG00000021824.12 Ap3m1 14 Lysosome 0 Medium Q9DA19 Corepressor interacting with RBPJ 1 OS=Mus musculus OX=10090 GN=Cir1 PE=1 SV=2 0.011 2.159 3 1 1 1 450 51.8 9.92 metabolic process;regulation of biological process cytoplasm;cytoskeleton;nucleus protein binding Pf10197 66935 ENSMUSG00000041777.11 Cir1 2 Notch signaling pathway 0 Medium Q8BSI6 R3H and coiled-coil domain-containing protein 1 OS=Mus musculus OX=10090 GN=R3hcc1 PE=1 SV=3 0.03 1.53 1 1 1 1 488 54.1 4.94 RNA binding "Pf01424, Pf10309" 71843 ENSMUSG00000034194.17 R3hcc1 14 0 Low B7ZC46 Septin-8 OS=Mus musculus OX=10090 GN=Septin8 PE=1 SV=1 0.079 1.122 2 1 1 1 440 50.9 6.09 24625.38086 1 cytoplasm;cytoskeleton nucleotide binding Pf00735 20362 ENSMUSG00000018398.18 Sept8 11 0 High A0A1L1SSA8 Transmembrane protein 205 (Fragment) OS=Mus musculus OX=10090 GN=Tmem205 PE=1 SV=1 0.004 3.427 10 1 1 1 173 19.6 9.41 membrane Pf13664 ENSMUSG00000040883.16 9 0 Medium Z4YJT3 La-related protein 1 OS=Mus musculus OX=10090 GN=Larp1 PE=1 SV=1 0.031 1.498 1 1 1 1 1072 121.1 8.79 cell proliferation;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane protein binding;RNA binding;translation regulator activity Pf05383 73158 ENSMUSG00000037331.15 Larp1 11 0 Low Q3TNL8 "Inositol 1,4,5-trisphosphate receptor-interacting protein OS=Mus musculus OX=10090 GN=Itprip PE=1 SV=1" 0.055 1.313 3 1 1 1 555 63.2 5.72 6351.557129 1 regulation of biological process membrane enzyme regulator activity;protein binding Pf03281 414801 ENSMUSG00000044948.16 Itprip 19 0 Medium A0A140LIS5 Arginine and glutamate-rich protein 1 (Fragment) OS=Mus musculus OX=10090 GN=Arglu1 PE=1 SV=1 0.02 1.754 4 1 1 1 215 25.9 10.62 7243.069824 1 ENSMUSG00000040459.11 8 0 Medium Q62426 Cystatin-B OS=Mus musculus OX=10090 GN=Cstb PE=1 SV=1 0.011 2.115 21 1 1 1 98 11 7.39 14566.71973 1 regulation of biological process;response to stimulus cytoplasm;cytosol;nucleus enzyme regulator activity;protein binding;RNA binding Pf00031 13014 ENSMUSG00000005054.7 Cstb 10 Neutrophil degranulation 0