Protein FDR Confidence: Combined Accession Description Exp. q-value: Combined Sum PEP Score Coverage [%] # Peptides # PSMs # Unique Peptides # AAs MW [kDa] calc. pI # Peptides (by Search Engine): A2 Sequest HT (BAT IgG) # Peptides (by Search Engine): B2 Sequest HT (BAT SKO) # Peptides (by Search Engine): C2 Sequest HT (BAT WT) # Peptides (by Search Engine): D2 Sequest HT (BAT HKO) # PSMs (by Search Engine): A2 Sequest HT (BAT IgG) # PSMs (by Search Engine): B2 Sequest HT (BAT SKO) # PSMs (by Search Engine): C2 Sequest HT (BAT WT) # PSMs (by Search Engine): D2 Sequest HT (BAT HKO) "Abundance: F6: Sample, BAT IgG" "Abundance: F7: Sample, BAT SKO" "Abundance: F8: Sample, BAT WT" "Abundance: F9: Sample, BAT HKO" "Abundances Count: F6: Sample, BAT IgG" "Abundances Count: F7: Sample, BAT SKO" "Abundances Count: F8: Sample, BAT WT" "Abundances Count: F9: Sample, BAT HKO" Modifications Biological Process Cellular Component Molecular Function Pfam IDs Entrez Gene ID Ensembl Gene ID Gene Symbol Chromosome Reactome Pathways KEGG Pathways # Razor Peptides High P20029 Endoplasmic reticulum chaperone BiP OS=Mus musculus OX=10090 GN=Hspa5 PE=1 SV=3 0 212.974 62 47 245 45 655 72.4 5.16 16 2 47 21 2 222 11958011.63 72708106.03 14019265.31 1679456580 20 37 27 55 cell communication;cell death;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;endoplasmic reticulum;extracellular;membrane;mitochondrion;nucleus;organelle lumen catalytic activity;nucleotide binding;protein binding "Pf00012, Pf01968, Pf06723" 14828 ENSMUSG00000026864.13 Hspa5 2 Thyroid hormone synthesis; Antigen processing and presentation; Protein export; Prion diseases; Protein processing in endoplasmic reticulum 3 High P00688 Pancreatic alpha-amylase OS=Mus musculus OX=10090 GN=Amy2 PE=1 SV=2 0 106.758 60 22 184 16 508 57.3 7.28 20 18 14 11 84 48 30 22 1195834212 253022929.7 164793454.1 53856147.72 32 31 31 28 metabolic process extracellular catalytic activity;metal ion binding "Pf00128, Pf02806" 109959; 100043688; 100043686; 100043684 ENSMUSG00000074268.4; ENSMUSG00000096770.2; ENSMUSG00000093931.2; ENSMUSG00000096569.2 Amy2a5; Amy2a2; Amy2a3; Amy2a4 3 Digestion of dietary carbohydrate Pancreatic secretion; Carbohydrate digestion and absorption; Metabolic pathways; Starch and sucrose metabolism 10 High Q8R0Y6 Cytosolic 10-formyltetrahydrofolate dehydrogenase OS=Mus musculus OX=10090 GN=Aldh1l1 PE=1 SV=1 0 132.225 60 44 161 44 902 98.6 5.91 33 24 41 46 38 77 411672.6865 149187176.5 124338281.6 186674166.2 9 46 46 46 metabolic process cytoplasm;cytosol;mitochondrion catalytic activity;protein binding "Pf00171, Pf00550, Pf00551, Pf02911" 107747 ENSMUSG00000030088.15 Aldh1l1 6 Metabolism of folate and pterines One carbon pool by folate 0 High P08113 Endoplasmin OS=Mus musculus OX=10090 GN=Hsp90b1 PE=1 SV=2 0 146.829 52 41 128 41 802 92.4 4.82 41 128 471933.5889 4124788.613 1466711.469 724583159 7 23 15 44 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytosol;endoplasmic reticulum;extracellular;membrane;nucleus;organelle lumen nucleotide binding;protein binding;RNA binding "Pf00183, Pf02518, Pf13589" 22027 ENSMUSG00000020048.13 Hsp90b1 10 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Scavenging by Class A Receptors; Trafficking and processing of endosomal TLR Thyroid hormone synthesis; Pathways in cancer; PI3K-Akt signaling pathway; Protein processing in endoplasmic reticulum; Estrogen signaling pathway; Prostate cancer 0 High F8VPN4 "Amylo-1,6-glucosidase, 4-alpha-glucanotransferase OS=Mus musculus OX=10090 GN=Agl PE=1 SV=1" 0 87.686 31 39 101 39 1532 174.2 6.74 1 21 22 33 1 25 27 48 13331347.79 46121594.14 47640346.41 57563533.42 34 39 37 38 metabolic process;response to stimulus cytoplasm;endoplasmic reticulum;nucleus catalytic activity;protein binding "Pf00128, Pf06202, Pf14699, Pf14701, Pf14702" 77559 ENSMUSG00000033400.14 Agl 3 Glycogen breakdown (glycogenolysis); Neutrophil degranulation Metabolic pathways; Starch and sucrose metabolism 0 High J3QJX3 Protein sel-1 homolog 1 OS=Mus musculus OX=10090 GN=Sel1l PE=1 SV=1 0 125.393 42 20 99 20 740 82.4 6.02 3 8 20 3 15 81 1339646.75 12732673.13 48317600.92 495377758.7 3 15 18 21 metabolic process;response to stimulus;transport protein binding Pf08238 ENSMUSG00000020964.14 12 0 High Q8K2C7 Protein OS-9 OS=Mus musculus OX=10090 GN=Os9 PE=1 SV=2 0 125.242 64 36 94 36 672 76.1 4.84 1 5 35 1 5 88 41756.46875 5342567.697 11027871.58 559104874.4 1 16 18 36 metabolic process;response to stimulus;transport endoplasmic reticulum;organelle lumen protein binding "Pf07915, Pf13015" 216440 ENSMUSG00000040462.13 Os9 10 Hedgehog ligand biogenesis; ABC-family proteins mediated transport; ER Quality Control Compartment (ERQC) Protein processing in endoplasmic reticulum 0 High Q99JY0 "Trifunctional enzyme subunit beta, mitochondrial OS=Mus musculus OX=10090 GN=Hadhb PE=1 SV=1" 0 50.302 49 22 84 22 475 51.4 9.38 7 16 12 21 7 25 13 39 52927992.45 53790320.91 43210116.97 88458906.25 21 21 21 22 metabolic process endoplasmic reticulum;membrane;mitochondrion catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00108, Pf00109, Pf02803" 231086 ENSMUSG00000059447.13 Hadhb 5 Beta oxidation of myristoyl-CoA to lauroyl-CoA; Acyl chain remodeling of CL; Beta oxidation of palmitoyl-CoA to myristoyl-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA "Fatty acid metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Fatty acid degradation; Fatty acid elongation" 0 High B1B0C7 Basement membrane-specific heparan sulfate proteoglycan core protein OS=Mus musculus OX=10090 GN=Hspg2 PE=1 SV=1 0 69.522 13 38 83 38 4375 468.7 6.48 21 12 19 21 23 14 21 25 67848184.91 25880568.86 26395583.91 25268137.19 37 36 34 35 cell differentiation;cell organization and biogenesis;transport extracellular metal ion binding;protein binding "Pf00008, Pf00047, Pf00052, Pf00053, Pf00054, Pf00057, Pf02210, Pf07679, Pf07686, Pf12785, Pf13385, Pf13895, Pf13927" 15530 ENSMUSG00000028763.17 Hspg2 4 HS-GAG degradation; A tetrasaccharide linker sequence is required for GAG synthesis; Laminin interactions; Degradation of the extracellular matrix; Signaling by GPCR; Retinoid metabolism and transport; Integrin cell surface interactions; HS-GAG biosynthesis; Non-integrin membrane-ECM interactions 0 High P38647 "Stress-70 protein, mitochondrial OS=Mus musculus OX=10090 GN=Hspa9 PE=1 SV=3" 0 59.143 38 22 79 22 679 73.4 6.07 6 17 14 20 8 22 18 31 48636877.05 57133569.56 30616638.61 54154341.31 21 22 19 22 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;mitochondrion;nucleus;organelle lumen nucleotide binding;protein binding;RNA binding "Pf00012, Pf06723" 15526 ENSMUSG00000024359.8 Hspa9 18 RNA degradation; Tuberculosis 0 High P00687 Alpha-amylase 1 OS=Mus musculus OX=10090 GN=Amy1 PE=1 SV=2 0 36.975 25 10 66 4 511 57.6 6.96 6 8 8 6 23 19 14 10 1116958.5 3924260.313 3588231.109 1051619.383 4 4 4 4 metabolic process extracellular catalytic activity;metal ion binding "Pf00128, Pf02806" 11722 ENSMUSG00000074264.12 Amy1 3 Digestion of dietary carbohydrate Carbohydrate digestion and absorption; Metabolic pathways; Starch and sucrose metabolism 0 High Q99KI0 "Aconitate hydratase, mitochondrial OS=Mus musculus OX=10090 GN=Aco2 PE=1 SV=1" 0 41.868 28 17 63 17 780 85.4 7.93 8 13 9 14 8 17 15 23 44556298.3 39432738.25 45015683.25 53390017.31 17 16 17 17 metabolic process;response to stimulus mitochondrion catalytic activity;metal ion binding "Pf00330, Pf00694" 11429 ENSMUSG00000022477.12 Aco2 15 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Biosynthesis of amino acids; 2-Oxocarboxylic acid metabolism; Carbon metabolism; Glyoxylate and dicarboxylate metabolism 0 High Q8K010 5-oxoprolinase OS=Mus musculus OX=10090 GN=Oplah PE=1 SV=1 0 56.14 25 26 60 26 1288 137.5 6.28 1 16 14 20 1 18 18 23 3864983.383 34019311.13 30624147.55 31960815 21 25 25 25 metabolic process cytosol catalytic activity;nucleotide binding "Pf01968, Pf02538, Pf05378" 75475 ENSMUSG00000022562.14 Oplah 15 Glutathione synthesis and recycling Glutathione metabolism 0 High Q8VEH8 Endoplasmic reticulum lectin 1 OS=Mus musculus OX=10090 GN=Erlec1 PE=1 SV=1 0 99.198 61 22 59 22 483 54.9 6.25 1 7 22 1 8 50 5514354.145 29036883.46 129063565.7 15 22 25 metabolic process;transport endoplasmic reticulum;organelle lumen protein binding "Pf07915, Pf13015" 66753 ENSMUSG00000020311.17 Erlec1 11 Hedgehog ligand biogenesis; ABC-family proteins mediated transport Protein processing in endoplasmic reticulum 0 High Q8BMS1 "Trifunctional enzyme subunit alpha, mitochondrial OS=Mus musculus OX=10090 GN=Hadha PE=1 SV=1" 0 44.988 30 18 57 18 763 82.6 9.14 8 14 12 13 9 16 14 18 29310927.56 35869962.25 16844863.59 24444423.64 19 19 19 19 metabolic process;response to stimulus membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding;protein binding "Pf00378, Pf00725, Pf02737" 97212 ENSMUSG00000025745.11 Hadha 5 Beta oxidation of myristoyl-CoA to lauroyl-CoA; Acyl chain remodeling of CL; Beta oxidation of palmitoyl-CoA to myristoyl-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA "Fatty acid metabolism; Tryptophan metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Lysine degradation; Fatty acid degradation; Butanoate metabolism; beta-Alanine metabolism; Propanoate metabolism; Fatty acid elongation; Carbon metabolism; Biosynthesis of unsaturated fatty acids" 0 High Q3U3J1 2-oxoisovalerate dehydrogenase subunit alpha OS=Mus musculus OX=10090 GN=Bckdha PE=1 SV=1 0 41.089 43 14 53 14 446 50.7 8.06 2 13 8 14 2 16 10 25 13595953.64 23396257.88 14366064.18 25527717.38 12 14 14 14 metabolic process mitochondrion catalytic activity;metal ion binding;protein binding "Pf00456, Pf00676" 12039 ENSMUSG00000060376.7 Bckdha 7 Glyoxylate metabolism and glycine degradation; Branched-chain amino acid catabolism "Valine, leucine and isoleucine degradation; Metabolic pathways; Propanoate metabolism" 0 High P53395 "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial OS=Mus musculus OX=10090 GN=Dbt PE=1 SV=2" 0 32.773 31 15 47 15 482 53.2 8.6 6 7 4 15 6 8 5 28 32418359 35315460.72 17692009.16 50696904.31 15 15 15 15 metabolic process mitochondrion;organelle lumen catalytic activity;protein binding "Pf00198, Pf00364, Pf02817" 13171 ENSMUSG00000000340.10 Dbt 3 Glyoxylate metabolism and glycine degradation; Branched-chain amino acid catabolism "Valine, leucine and isoleucine degradation; Metabolic pathways; Propanoate metabolism" 0 High A2A513 "Keratin, type I cytoskeletal 10 OS=Mus musculus OX=10090 GN=Krt10 PE=1 SV=1" 0 25.789 12 8 44 4 561 57 5.07 2 7 5 8 2 15 10 17 73170615.13 75560021.06 45117380 102893260.9 10 11 11 11 cell differentiation;cell organization and biogenesis;metabolic process;response to stimulus cytoplasm;cytoskeleton;membrane;nucleus protein binding;structural molecule activity Pf00038 16661 ENSMUSG00000019761.10 Krt10 11 Formation of the cornified envelope Staphylococcus aureus infection 7 High P20152 Vimentin OS=Mus musculus OX=10090 GN=Vim PE=1 SV=3 0 29.312 34 15 39 15 466 53.7 5.12 12 4 6 12 12 4 8 15 39561595.25 9322156.719 14042678.63 19753889.47 15 15 15 15 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane protein binding;RNA binding;structural molecule activity "Pf00038, Pf04111, Pf04156, Pf04732, Pf05622, Pf10186" 22352 ENSMUSG00000026728.9 Vim 2 Striated Muscle Contraction; Caspase-mediated cleavage of cytoskeletal proteins MicroRNAs in cancer; Epstein-Barr virus infection 0 High E9PUQ5 Golgin subfamily A member 2 OS=Mus musculus OX=10090 GN=Golga2 PE=1 SV=1 0 36.341 22 20 35 20 1026 116.2 5.05 11 6 16 11 6 18 28649.24023 22651781.38 14127936.17 26272896.69 2 20 19 20 cell division;cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;Golgi;membrane;nucleus protein binding "Pf12128, Pf15070" 99412 ENSMUSG00000002546.16 Golga2 2 0 High Q9ET01 "Glycogen phosphorylase, liver form OS=Mus musculus OX=10090 GN=Pygl PE=1 SV=4" 0 30.613 20 16 35 11 850 97.4 7.09 2 10 10 8 2 11 12 10 11928733.13 17665017.16 22979764.88 12836289.91 14 15 16 15 Met-loss+Acetyl [N-Term] cell death;metabolic process cytoplasm catalytic activity;nucleotide binding;protein binding Pf00343 110095 ENSMUSG00000021069.16 Pygl 12 Glycogen breakdown (glycogenolysis); Neutrophil degranulation Insulin signaling pathway; Metabolic pathways; Insulin resistance; Starch and sucrose metabolism; Glucagon signaling pathway 5 High Q8BWT1 "3-ketoacyl-CoA thiolase, mitochondrial OS=Mus musculus OX=10090 GN=Acaa2 PE=1 SV=3" 0 43.428 51 13 35 13 397 41.8 8.09 2 5 4 11 2 8 5 20 23787361 18048604.66 20114874.2 75933856.5 13 13 12 13 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion;organelle lumen catalytic activity;RNA binding "Pf00108, Pf02801, Pf02803" 52538 ENSMUSG00000036880.9 Acaa2 18 Mitochondrial Fatty Acid Beta-Oxidation "Fatty acid metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Fatty acid degradation; Fatty acid elongation" 0 High P21981 Protein-glutamine gamma-glutamyltransferase 2 OS=Mus musculus OX=10090 GN=Tgm2 PE=1 SV=4 0 24.086 20 12 35 12 686 77 5.1 5 9 8 8 6 9 8 12 13248802.72 11421846.38 10587012.36 8120470.063 11 11 11 11 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;endoplasmic reticulum;membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00868, Pf00927, Pf01841" 21817 ENSMUSG00000037820.15 Tgm2 2 Huntington's disease 0 High P50544 "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Acadvl PE=1 SV=3" 0 28.385 26 13 29 13 656 70.8 8.75 1 5 4 12 1 6 5 17 6808970.844 7464322.563 7653656.281 14023355.56 13 13 13 13 cell differentiation;metabolic process;regulation of biological process;response to stimulus cytosol;membrane;mitochondrion;nucleus catalytic activity;nucleotide binding "Pf00441, Pf02770, Pf02771, Pf08028" 11370 ENSMUSG00000018574.14 Acadvl 11 Beta oxidation of palmitoyl-CoA to myristoyl-CoA Fatty acid metabolism; Metabolic pathways; Fatty acid degradation 0 High P63017 Heat shock cognate 71 kDa protein OS=Mus musculus OX=10090 GN=Hspa8 PE=1 SV=1 0 26.163 18 11 29 9 646 70.8 5.52 2 6 5 8 2 7 6 14 7318149.844 8111789.219 7977250.625 7284857.031 9 8 8 9 cell organization and biogenesis;metabolic process;regulation of biological process;transport cell surface;cytoplasm;cytosol;endosome;membrane;nucleus;spliceosomal complex;vacuole catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00012, Pf02463, Pf06723" 15481 ENSMUSG00000015656.17 Hspa8 9 "Regulation of HSF1-mediated heat shock response; Golgi Associated Vesicle Biogenesis; mRNA Splicing - Major Pathway; Attenuation phase; Neutrophil degranulation; AUF1 (hnRNP D0) binds and destabilizes mRNA; GABA synthesis, release, reuptake and degradation; HSP90 chaperone cycle for steroid hormone receptors (SHR); Protein methylation; Clathrin-mediated endocytosis" Endocytosis; MAPK signaling pathway; Toxoplasmosis; Epstein-Barr virus infection; Spliceosome; Legionellosis; Influenza A; Antigen processing and presentation; Protein processing in endoplasmic reticulum; Estrogen signaling pathway; Measles; Longevity regulating pathway - multiple species 0 High Q6P3A8 "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial OS=Mus musculus OX=10090 GN=Bckdhb PE=1 SV=2" 0 23.068 26 8 29 8 390 42.9 6.7 1 6 4 8 1 9 5 14 11840192.38 16528773.02 6320577.438 19796033.16 8 7 6 8 metabolic process membrane;mitochondrion;organelle lumen catalytic activity;protein binding "Pf02779, Pf02780" 12040 ENSMUSG00000032263.14 Bckdhb 9 Glyoxylate metabolism and glycine degradation; Branched-chain amino acid catabolism "Valine, leucine and isoleucine degradation; Metabolic pathways; Propanoate metabolism" 0 High Q9WUM5 "Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial OS=Mus musculus OX=10090 GN=Suclg1 PE=1 SV=4" 0 26.267 25 8 28 8 346 36.1 9.39 1 3 4 8 1 6 5 16 14675323.06 20330879.75 21740326.59 58782881.63 8 9 9 9 metabolic process cytosol;membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00549, Pf02629, Pf13607" 56451 ENSMUSG00000052738.14 Suclg1 6 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Propanoate metabolism; Carbon metabolism 0 High Q60597 "2-oxoglutarate dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Ogdh PE=1 SV=3" 0 31.499 21 16 27 16 1023 116.4 6.83 10 4 1 11 11 4 1 11 39436773.5 13143834.81 9981831.289 13138433.7 15 15 15 15 cellular component movement;metabolic process cytosol;membrane;mitochondrion;organelle lumen catalytic activity;metal ion binding;protein binding "Pf00676, Pf02779" 18293 ENSMUSG00000020456.17 Ogdh 11 Lysine catabolism; Citric acid cycle (TCA cycle); Glyoxylate metabolism and glycine degradation Tryptophan metabolism; Citrate cycle (TCA cycle); Metabolic pathways; Lysine degradation; Carbon metabolism 0 High Q6IFZ6 "Keratin, type II cytoskeletal 1b OS=Mus musculus OX=10090 GN=Krt77 PE=1 SV=1" 0 13.365 6 3 25 1 572 61.3 8.02 1 3 2 3 1 8 4 12 7643735 12778028 5623268 9234461 1 1 1 1 cytoskeleton protein binding;structural molecule activity "Pf00038, Pf09728, Pf13166" 406220 ENSMUSG00000067594.5 Krt77 15 Formation of the cornified envelope 0 High Q3TTY5 "Keratin, type II cytoskeletal 2 epidermal OS=Mus musculus OX=10090 GN=Krt2 PE=1 SV=1" 0 16.955 7 7 25 5 707 70.9 8.06 4 5 2 6 5 8 2 10 62356756 57140897.75 35507691.44 81874325.63 8 8 8 8 cell organization and biogenesis;cell proliferation;cellular component movement;metabolic process cytoskeleton;membrane;nucleus protein binding;structural molecule activity "Pf00038, Pf13166" 16681 ENSMUSG00000064201.8 Krt2 15 Formation of the cornified envelope 2 High E9PUU4 Gem-associated protein 5 OS=Mus musculus OX=10090 GN=Gemin5 PE=1 SV=1 0 17.605 8 11 24 11 1503 166.6 6.74 8 8 7 9 8 7 7419.044922 7140677.313 15206934.17 4624620.063 1 10 11 9 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;cytosol;membrane;nucleus protein binding;RNA binding Pf00400 216766 ENSMUSG00000037275.14 Gemin5 11 0 High Q6NXH9 "Keratin, type II cytoskeletal 73 OS=Mus musculus OX=10090 GN=Krt73 PE=1 SV=1" 0 13.467 8 5 22 1 539 58.9 8.09 3 3 2 5 4 6 2 10 15923522.25 28001054.34 16011345.16 29345047.97 4 4 4 4 transport nucleus catalytic activity;motor activity;protein binding;structural molecule activity "Pf00038, Pf01576, Pf03962, Pf04156, Pf08614, Pf09728, Pf09763, Pf11559, Pf12128, Pf13514" 223915 ENSMUSG00000063661.5 Krt73 15 Formation of the cornified envelope 3 High P19096 Fatty acid synthase OS=Mus musculus OX=10090 GN=Fasn PE=1 SV=2 0 23.518 8 16 21 16 2504 272.3 6.58 8 1 2 9 9 1 2 9 16750413.44 4110250.368 3184167.391 7060646.945 15 14 12 14 cell differentiation;metabolic process;response to stimulus cytoplasm;cytosol;Golgi;membrane;mitochondrion catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00106, Pf00107, Pf00109, Pf00550, Pf00698, Pf00975, Pf02801, Pf08241, Pf08242, Pf08659, Pf12847, Pf13489, Pf13602, Pf13847, Pf14765" 14104 ENSMUSG00000025153.9 Fasn 11 ChREBP activates metabolic gene expression; Fatty acyl-CoA biosynthesis; Vitamin B5 (pantothenate) metabolism Fatty acid metabolism; Insulin signaling pathway; Metabolic pathways; AMPK signaling pathway; Fatty acid biosynthesis 0 High P08730 "Keratin, type I cytoskeletal 13 OS=Mus musculus OX=10090 GN=Krt13 PE=1 SV=2" 0 11.836 6 4 20 1 437 47.7 4.86 1 4 1 4 1 7 2 10 28846786 33711632 33375536 33915412 1 1 1 1 cell organization and biogenesis;response to stimulus cytoskeleton;nucleus protein binding;structural molecule activity "Pf00038, Pf13514" 16663 ENSMUSG00000044041.4 Krt13 11 Formation of the cornified envelope 0 High A0A0A0MQF6 Glyceraldehyde-3-phosphate dehydrogenase OS=Mus musculus OX=10090 GN=Gapdh PE=1 SV=1 0 30.826 38 11 20 11 359 38.6 8.97 1 11 1 19 3966467.789 3233540.906 4888899.078 40881245.13 9 8 8 11 cell death;cell organization and biogenesis;defense response;development;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;mitochondrion;nucleus catalytic activity;enzyme regulator activity;nucleotide binding;protein binding "Pf00044, Pf02800" 14433 ENSMUSG00000057666.18 Gapdh 6 0 High Q922U2 "Keratin, type II cytoskeletal 5 OS=Mus musculus OX=10090 GN=Krt5 PE=1 SV=1" 0 12.278 10 7 19 3 580 61.7 7.75 2 5 2 5 3 6 3 7 39282676.69 30619598.5 18905453.48 33855932.05 5 5 4 5 metabolic process cytoplasm;membrane;mitochondrion;nucleus catalytic activity;motor activity;protein binding;structural molecule activity "Pf00038, Pf01576, Pf03961, Pf04111, Pf05957" 110308 ENSMUSG00000061527.6 Krt5 15 Type I hemidesmosome assembly; Formation of the cornified envelope 2 High Q9Z2I9 "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial OS=Mus musculus OX=10090 GN=Sucla2 PE=1 SV=2" 0 20.797 22 11 19 11 463 50.1 7.01 2 3 2 10 2 3 2 12 7657774.438 7510677.469 6405013.438 36377288.88 11 11 10 11 metabolic process mitochondrion catalytic activity;metal ion binding;nucleotide binding "Pf00549, Pf02222, Pf02786, Pf08442, Pf13535, Pf13549" 20916 ENSMUSG00000022110.13 Sucla2 14 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Propanoate metabolism; Carbon metabolism 0 High P35486 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Mus musculus OX=10090 GN=Pdha1 PE=1 SV=1" 0 18.58 30 10 18 10 390 43.2 8.19 1 2 10 1 2 15 4274411.844 1829480.586 2881875.102 11221465.39 6 8 8 9 metabolic process mitochondrion;nucleus;organelle lumen catalytic activity Pf00676 18597 ENSMUSG00000031299.10 Pdha1 X Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Glyoxylate metabolism and glycine degradation Pyruvate metabolism; Citrate cycle (TCA cycle); Metabolic pathways; Glycolysis / Gluconeogenesis; HIF-1 signaling pathway; Carbon metabolism; Central carbon metabolism in cancer; Glucagon signaling pathway 0 High Q8BFR5 "Elongation factor Tu, mitochondrial OS=Mus musculus OX=10090 GN=Tufm PE=1 SV=1" 0 22.926 27 10 18 10 452 49.5 7.56 2 2 10 2 2 14 2618840.32 4498299.469 4551752.25 11321574.75 8 10 9 10 metabolic process;response to stimulus membrane;mitochondrion catalytic activity;nucleotide binding;RNA binding "Pf00009, Pf03143, Pf03144" 233870 ENSMUSG00000073838.10 Tufm 7 0 High Q924X2 "Carnitine O-palmitoyltransferase 1, muscle isoform OS=Mus musculus OX=10090 GN=Cpt1b PE=1 SV=1" 0 23.518 14 12 18 12 772 88.2 8.38 12 18 2165338.32 1483970.07 2714918.195 14500267.28 10 11 10 12 metabolic process;transport membrane;mitochondrion catalytic activity Pf00755 12895 ENSMUSG00000078937.8 Cpt1b 15 Signaling by Retinoic Acid; Import of palmitoyl-CoA into the mitochondrial matrix PPAR signaling pathway; Fatty acid metabolism; Fatty acid degradation; Insulin resistance; Adipocytokine signaling pathway; AMPK signaling pathway; Glucagon signaling pathway 0 High Q8BH95 "Enoyl-CoA hydratase, mitochondrial OS=Mus musculus OX=10090 GN=Echs1 PE=1 SV=1" 0 11.123 23 5 18 5 290 31.5 8.48 2 4 3 5 2 4 4 8 10546732.56 7723771.156 9113004.344 9875297.844 5 5 5 5 metabolic process mitochondrion;organelle lumen catalytic activity Pf00378 93747 ENSMUSG00000025465.13 Echs1 7 Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA "Fatty acid metabolism; Tryptophan metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Lysine degradation; Fatty acid degradation; Butanoate metabolism; beta-Alanine metabolism; Propanoate metabolism; Fatty acid elongation; Carbon metabolism" 0 High P04104 "Keratin, type II cytoskeletal 1 OS=Mus musculus OX=10090 GN=Krt1 PE=1 SV=4" 0 13.91 4 3 18 2 637 65.6 8.15 1 2 3 3 1 4 4 9 12442099 33673002 10163659 33093275.5 2 2 2 2 defense response;metabolic process;regulation of biological process;response to stimulus cytoskeleton;membrane;nucleus structural molecule activity "Pf00038, Pf11853" 16678 ENSMUSG00000046834.6 Krt1 15 Formation of the cornified envelope; Neutrophil degranulation 0 High P12242 Mitochondrial brown fat uncoupling protein 1 OS=Mus musculus OX=10090 GN=Ucp1 PE=1 SV=2 0 24.598 25 8 17 8 307 33.2 9.14 1 1 1 8 2 1 1 13 8810358.063 5568479.906 5793803.125 21166575.56 9 9 8 8 Met-loss [N-Term] cell differentiation;regulation of biological process;response to stimulus;transport membrane;mitochondrion nucleotide binding;protein binding;transporter activity Pf00153 22227 ENSMUSG00000031710.4 Ucp1 8 The proton buffering model; The fatty acid cycling model PPAR signaling pathway; Huntington's disease 0 High Q8CGN5 Perilipin-1 OS=Mus musculus OX=10090 GN=Plin1 PE=1 SV=2 0 21.574 29 12 16 12 517 55.6 7.01 2 12 2 14 2689595.391 3478954.422 3874819.117 8301135.281 11 11 11 11 metabolic process cytosol;endoplasmic reticulum protein binding Pf03036 103968 ENSMUSG00000030546.14 Plin1 7 PPAR signaling pathway; Regulation of lipolysis in adipocytes 0 High Q3UV17 "Keratin, type II cytoskeletal 2 oral OS=Mus musculus OX=10090 GN=Krt76 PE=1 SV=1" 0 7.68 5 4 16 1 594 62.8 8.43 2 3 1 3 3 6 1 6 15100681.21 12617982.5 8301780.484 16659094 1 1 1 1 nucleus catalytic activity;motor activity;protein binding;structural molecule activity "Pf00038, Pf01576, Pf10473" 77055 ENSMUSG00000075402.1 Krt76 15 Formation of the cornified envelope 0 High Q64521 "Glycerol-3-phosphate dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Gpd2 PE=1 SV=2" 0 11.817 12 7 16 7 727 80.9 6.61 5 1 3 6 5 1 3 7 4919119.828 7825042.125 1993992.359 2714832.281 7 7 6 6 metabolic process membrane;mitochondrion catalytic activity;metal ion binding "Pf00890, Pf01266, Pf03486, Pf07992, Pf12831, Pf13499" 14571 ENSMUSG00000026827.12 Gpd2 2 Triglyceride catabolism; Synthesis of PA Glycerophospholipid metabolism 0 High P25444 40S ribosomal protein S2 OS=Mus musculus OX=10090 GN=Rps2 PE=1 SV=3 0 10.252 23 7 15 7 293 31.2 10.24 1 5 3 5 1 6 3 5 1813261.234 6595738.938 4417118.125 5366401.844 5 7 7 7 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity "Pf00333, Pf03719" 16898; 546298 ENSMUSG00000044533.15 Rps2; Rps2-ps13 17; X Ribosome 0 High Q62425 Cytochrome c oxidase subunit NDUFA4 OS=Mus musculus OX=10090 GN=Ndufa4 PE=1 SV=2 0 10.518 48 4 15 4 82 9.3 9.52 1 1 2 4 1 1 3 10 4400564.859 4773277.375 6437162.719 50189484.5 4 4 4 4 metabolic process;transport membrane;mitochondrion catalytic activity;protein binding;transporter activity Pf06522 17992 ENSMUSG00000029632.7 Ndufa4 6 Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High P51881 ADP/ATP translocase 2 OS=Mus musculus OX=10090 GN=Slc25a5 PE=1 SV=3 0 16.74 29 9 15 4 298 32.9 9.73 9 15 2451778.18 3080167.453 4632253.719 38414570.5 7 9 9 9 Met-loss+Acetyl [N-Term] cell organization and biogenesis;regulation of biological process;transport membrane;mitochondrion;nucleus protein binding;RNA binding;transporter activity Pf00153 11740 ENSMUSG00000016319.3 Slc25a5 X Regulation of insulin secretion HTLV-I infection; Huntington's disease; Parkinson's disease; cGMP-PKG signaling pathway; Calcium signaling pathway 5 High G5E8R3 Pyruvate carboxylase OS=Mus musculus OX=10090 GN=Pcx PE=1 SV=1 0 12.361 8 8 14 8 1178 129.6 6.71 2 1 3 8 2 1 3 8 5987773.563 2552601.422 2507593.82 3930277.266 8 8 8 8 metabolic process;regulation of biological process cytoplasm;membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00289, Pf00364, Pf00682, Pf02222, Pf02436, Pf02785, Pf02786, Pf07478, Pf08443, Pf13533, Pf13535, Pf15632" 18563 ENSMUSG00000024892.15 Pcx 19 Biotin transport and metabolism; Gluconeogenesis 0 High Q8CAQ8 MICOS complex subunit Mic60 OS=Mus musculus OX=10090 GN=Immt PE=1 SV=1 0 21.129 13 9 14 1 757 83.8 6.61 1 1 3 9 1 1 3 9 5735570.906 2331672.031 2638997.969 8691592.25 8 7 7 8 cell organization and biogenesis;cellular homeostasis membrane;mitochondrion protein binding;RNA binding Pf09731 76614 ENSMUSG00000052337.15 Immt 6 7 High P60710 "Actin, cytoplasmic 1 OS=Mus musculus OX=10090 GN=Actb PE=1 SV=1" 0 15.108 24 8 14 2 375 41.7 5.48 1 1 1 7 1 1 1 11 7449369.5 5070108.813 5109048.938 13689964.25 8 8 8 8 cell organization and biogenesis;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;nucleus DNA binding;nucleotide binding;protein binding Pf00022 11461 ENSMUSG00000029580.14 Actb 5 Interaction between L1 and Ankyrins; DNA Damage Recognition in GG-NER; VEGFA-VEGFR2 Pathway; Adherens junctions interactions; UCH proteinases; Regulation of actin dynamics for phagocytic cup formation; B-WICH complex positively regulates rRNA expression; RHO GTPases activate IQGAPs; Formation of annular gap junctions; RHO GTPases Activate Formins; Recycling pathway of L1; RHO GTPases Activate WASPs and WAVEs; Cell-extracellular matrix interactions; Clathrin-mediated endocytosis; EPHB-mediated forward signaling Oxytocin signaling pathway; Leukocyte transendothelial migration; Hypertrophic cardiomyopathy (HCM); Regulation of actin cytoskeleton; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Focal adhesion; Hippo signaling pathway; Platelet activation; Dilated cardiomyopathy; Adherens junction; Phagosome; Proteoglycans in cancer; Salmonella infection; Thyroid hormone signaling pathway; Rap1 signaling pathway; Influenza A; Viral myocarditis; Tight junction; Gastric acid secretion; Bacterial invasion of epithelial cells; Apoptosis 6 High Q91VA7 "Isocitrate dehydrogenase [NAD] subunit, mitochondrial OS=Mus musculus OX=10090 GN=Idh3b PE=1 SV=1" 0 18.618 27 9 14 9 384 42.2 8.6 1 1 9 1 1 12 3094912.172 4060059.781 4540880.688 17393882.81 8 9 9 9 metabolic process mitochondrion;nucleus catalytic activity;metal ion binding;nucleotide binding Pf00180 170718 ENSMUSG00000027406.12 Idh3b 2 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Biosynthesis of amino acids; 2-Oxocarboxylic acid metabolism; Carbon metabolism 0 High E9PV24 Fibrinogen alpha chain OS=Mus musculus OX=10090 GN=Fga PE=1 SV=1 0 15.136 8 6 14 6 789 87.4 6.11 1 3 4 4 1 4 5 4 5335369.156 7176647.938 3584051.969 4177226.406 6 6 5 6 cell organization and biogenesis;coagulation;defense response;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;endoplasmic reticulum;extracellular metal ion binding;protein binding;structural molecule activity "Pf00147, Pf08702, Pf12160" 14161 ENSMUSG00000028001.16 Fga 3 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); p130Cas linkage to MAPK signaling for integrins; Post-translational protein phosphorylation; Integrin cell surface interactions; Regulation of TLR by endogenous ligand; Common Pathway of Fibrin Clot Formation; GRB2:SOS provides linkage to MAPK signaling for Integrins ; Platelet degranulation Platelet activation; Complement and coagulation cascades 0 High Q9D2G2 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Mus musculus OX=10090 GN=Dlst PE=1 SV=1" 0 11.286 9 4 13 4 454 49 8.95 2 3 3 1 3 4 4 2 53546853.5 7799228 7327900.313 4092669.813 4 4 4 3 metabolic process membrane;mitochondrion;nucleus catalytic activity;protein binding "Pf00198, Pf00364" 78920 ENSMUSG00000004789.9 Dlst 12 Lysine catabolism; Citric acid cycle (TCA cycle); Glyoxylate metabolism and glycine degradation Citrate cycle (TCA cycle); Metabolic pathways; Lysine degradation; Carbon metabolism 0 High E9Q0F0 Keratin 78 OS=Mus musculus OX=10090 GN=Krt78 PE=1 SV=1 0 6.388 1 1 13 1 1068 112.2 7.97 1 1 1 1 1 4 3 5 9708293 13843181.75 7279048.375 14983779.5 2 2 2 2 cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;transport cytoskeleton;Golgi;membrane catalytic activity;motor activity;protein binding;structural molecule activity;transporter activity "Pf00038, Pf01576, Pf02050, Pf02321, Pf02403, Pf03280, Pf03938, Pf04111, Pf04156, Pf04740, Pf04977, Pf05008, Pf05103, Pf05335, Pf05483, Pf05557, Pf05622, Pf05642, Pf05667, Pf05911, Pf06013, Pf06133, Pf06160, Pf06810, Pf07321, Pf07926, Pf08614, Pf09606, Pf09726, Pf09731, Pf09755, Pf11559, Pf11932, Pf12128, Pf12325, Pf12329, Pf12795, Pf13514, Pf13851, Pf14362, Pf15070, Pf15397" 332131 ENSMUSG00000050463.8 Krt78 15 Formation of the cornified envelope 0 High Q3U7K7 E3 ubiquitin-protein ligase TRIM21 OS=Mus musculus OX=10090 GN=Trim21 PE=1 SV=1 0 17.177 19 9 13 9 462 53.3 6.7 1 1 9 1 1 11 3293574.219 4287074.431 3042554.055 5771440.773 7 8 7 8 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus catalytic activity;DNA binding;metal ion binding;protein binding;RNA binding "Pf00097, Pf00622, Pf00643, Pf13445, Pf13639, Pf13765, Pf13920, Pf13923, Pf14634, Pf14835, Pf15227" 20821 ENSMUSG00000030966.13 Trim21 7 Antigen processing: Ubiquitination & Proteasome degradation; Regulation of innate immune responses to cytosolic DNA Systemic lupus erythematosus 0 High P01027 Complement C3 OS=Mus musculus OX=10090 GN=C3 PE=1 SV=3 0 13.299 4 7 13 7 1663 186.4 6.73 1 3 7 1 4 8 290670.9922 7250573.125 18543922.13 23106154.25 2 6 7 7 cell organization and biogenesis;coagulation;defense response;metabolic process;regulation of biological process;response to stimulus extracellular enzyme regulator activity;protein binding "Pf00207, Pf01759, Pf01821, Pf01835, Pf07677, Pf07678, Pf07703, Pf10569, Pf11974" 12266 ENSMUSG00000024164.15 C3 17 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Regulation of Complement cascade; Peptide ligand-binding receptors; G alpha (i) signalling events; Activation of C3 and C5; Post-translational protein phosphorylation; Alternative complement activation; Neutrophil degranulation; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Herpes simplex infection; Chagas disease (American trypanosomiasis); Staphylococcus aureus infection; Tuberculosis; Phagosome; Complement and coagulation cascades; Pertussis; Legionellosis; Systemic lupus erythematosus; Leishmaniasis; Viral carcinogenesis 0 High A0A0U1RP81 MICOS complex subunit MIC60 OS=Mus musculus OX=10090 GN=Immt PE=1 SV=1 0 20.096 20 9 12 1 488 53.7 8.66 1 2 9 1 2 9 772176.375 380917.75 961217.4375 1 1 1 cellular homeostasis membrane;mitochondrion Pf09731 ENSMUSG00000052337.15 6 0 High P63268 "Actin, gamma-enteric smooth muscle OS=Mus musculus OX=10090 GN=Actg2 PE=1 SV=1" 0 13.264 21 7 12 1 376 41.9 5.48 1 1 1 6 1 1 1 9 229698.9531 209114.6406 261812.0938 911949.9375 1 1 1 1 regulation of biological process cytoplasm;cytoskeleton nucleotide binding Pf00022 11468 ENSMUSG00000059430.14 Actg2 6 Smooth Muscle Contraction Vascular smooth muscle contraction 0 High Q8CI94 "Glycogen phosphorylase, brain form OS=Mus musculus OX=10090 GN=Pygb PE=1 SV=3" 0 12.546 10 8 12 3 843 96.7 6.73 3 4 5 3 4 5 255267.5625 718832.7969 1107187.938 1469545.344 2 3 3 3 Met-loss+Acetyl [N-Term] metabolic process cytoplasm;membrane catalytic activity;protein binding Pf00343 110078 ENSMUSG00000033059.7 Pygb 2 Neutrophil degranulation Insulin signaling pathway; Metabolic pathways; Insulin resistance; Starch and sucrose metabolism; Glucagon signaling pathway 0 High Q9Z2K1 "Keratin, type I cytoskeletal 16 OS=Mus musculus OX=10090 GN=Krt16 PE=1 SV=3" 0 7.792 6 3 12 1 469 51.6 5.2 2 1 3 5 2 5 879170.5625 1296428 1 1 cell differentiation;cell organization and biogenesis;cellular component movement;defense response;regulation of biological process;response to stimulus cytoskeleton;nucleus protein binding;structural molecule activity "Pf00038, Pf13514" 16666 ENSMUSG00000053797.10 Krt16 11 Formation of the cornified envelope 0 High G5E8G0 Heterogeneous nuclear ribonucleoprotein D0 OS=Mus musculus OX=10090 GN=Hnrnpd PE=1 SV=1 0 14.701 23 6 12 1 287 30.6 8.41 1 1 3 6 1 1 3 7 770567.3125 3099773.25 4302670 5419939 1 1 1 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;nucleus DNA binding;protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 11991 ENSMUSG00000000568.15 Hnrnpd 5 0 High P62702 "40S ribosomal protein S4, X isoform OS=Mus musculus OX=10090 GN=Rps4x PE=1 SV=2" 0 12.576 21 6 12 6 263 29.6 10.15 1 2 1 6 1 2 1 8 2056315.445 4521353.609 2178015.18 5731645.484 6 7 6 7 development;metabolic process;regulation of biological process cytoplasm;membrane;nucleus;ribosome RNA binding;structural molecule activity "Pf00900, Pf08071" 20102 ENSMUSG00000031320.9 Rps4x X "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High P01872 Immunoglobulin heavy constant mu OS=Mus musculus OX=10090 GN=Ighm PE=1 SV=2 0 12.319 13 5 11 5 454 49.9 7.01 2 2 4 3 3 5 3762441.594 6276233.719 3606911.953 3747408.547 4 5 5 5 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytosol;extracellular;membrane protein binding;receptor activity;signal transducer activity "Pf07654, Pf07679" 16019 Ighm 12 0 High Q8VEK3 Heterogeneous nuclear ribonucleoprotein U OS=Mus musculus OX=10090 GN=Hnrnpu PE=1 SV=1 0 12.431 9 7 11 7 800 87.9 6.24 1 2 3 5 1 2 3 5 4618115.141 5348296.453 6196310.688 5498747.906 7 7 7 7 cell differentiation;metabolic process;regulation of biological process;response to stimulus cell surface;chromosome;cytoplasm;membrane;nucleus;spliceosomal complex DNA binding;nucleotide binding;protein binding;RNA binding "Pf00622, Pf13671" 51810 ENSMUSG00000039630.10; ENSMUSG00000111145.1 Hnrnpu 1; CHR_MG4281_PATCH mRNA Splicing - Major Pathway Spliceosome 0 High P48962 ADP/ATP translocase 1 OS=Mus musculus OX=10090 GN=Slc25a4 PE=1 SV=4 0 12.961 21 7 11 2 298 32.9 9.72 7 11 110120.8418 130136.9688 296516 2444971.75 2 1 2 2 cell organization and biogenesis;regulation of biological process;transport membrane;mitochondrion;nucleus protein binding;transporter activity Pf00153 11739 ENSMUSG00000031633.4 Slc25a4 8 Regulation of insulin secretion HTLV-I infection; Huntington's disease; Parkinson's disease; cGMP-PKG signaling pathway; Calcium signaling pathway 0 High Q99LC5 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Mus musculus OX=10090 GN=Etfa PE=1 SV=2" 0 11.59 17 6 10 6 333 35 8.38 1 2 6 1 2 7 1334238.031 1461792.203 1493673.844 7441864.125 4 5 4 6 metabolic process;transport mitochondrion;organelle lumen catalytic activity;nucleotide binding;protein binding "Pf00766, Pf01012" 110842 ENSMUSG00000032314.14 Etfa 9 Respiratory electron transport 0 High E9QM38 Solute carrier family 12 member 2 OS=Mus musculus OX=10090 GN=Slc12a2 PE=1 SV=1 0 8.636 5 4 10 4 1206 130.6 6.52 3 4 1 4 5 1 1325460.25 1442185.797 623320.9375 2 3 2 cellular homeostasis;regulation of biological process;response to stimulus;transport membrane catalytic activity;nucleotide binding;protein binding;transporter activity "Pf00324, Pf08403, Pf13520" 20496 ENSMUSG00000024597.10 Slc12a2 18 Cation-coupled Chloride cotransporters Pancreatic secretion; Salivary secretion 0 High A0A087WS56 Fibronectin OS=Mus musculus OX=10090 GN=Fn1 PE=1 SV=1 0 11.437 4 8 10 8 2266 249.4 5.82 2 2 3 3 2 2 3 3 3362041.336 3571076.406 3937049.984 2610385.547 7 8 8 7 cell differentiation;cell organization and biogenesis;cellular component movement;defense response;metabolic process;regulation of biological process;response to stimulus extracellular;membrane enzyme regulator activity;metal ion binding;protein binding "Pf00039, Pf00040, Pf00041" 14268 ENSMUSG00000026193.15 Fn1 1 0 High Q9Z1R9 "Protease, serine 1 (trypsin 1) OS=Mus musculus OX=10090 GN=Prss1 PE=1 SV=1" 0 5.631 8 1 10 1 246 26.1 4.94 1 1 1 1 2 3 2 3 72635097 65818337.81 40569475.81 36177133.91 2 2 2 2 metabolic process catalytic activity Pf00089 114228 ENSMUSG00000062751.5 Prss1 6 "Cobalamin (Cbl, vitamin B12) transport and metabolism; Neutrophil degranulation; Collagen degradation; Antimicrobial peptides; Activation of Matrix Metalloproteinases" 0 High Q6IFX2 "Keratin, type I cytoskeletal 42 OS=Mus musculus OX=10090 GN=Krt42 PE=1 SV=1" 0 6.98 6 3 10 2 452 50.1 5.16 1 2 2 3 1 3 2 4 3142363.75 4083572.375 2025023.281 3236863.25 2 2 2 2 cytoplasm structural molecule activity "Pf00038, Pf04156, Pf08317, Pf13166, Pf13514" 68239 ENSMUSG00000053654.7 Krt42 11 0 High E9PUM3 "Alpha-1,4 glucan phosphorylase OS=Mus musculus OX=10090 GN=Pygm PE=1 SV=1" 0 9.634 8 7 10 2 754 87.5 8.51 3 4 3 3 4 3 80790.33594 279523.6953 1174742.75 536796.1094 1 2 2 2 metabolic process catalytic activity Pf00343 ENSMUSG00000032648.14; ENSMUSG00000106877.3 19; CHR_MG4249_PATCH 0 High Q60668 Heterogeneous nuclear ribonucleoprotein D0 OS=Mus musculus OX=10090 GN=Hnrnpd PE=1 SV=2 0 12.329 18 6 10 1 355 38.3 7.81 1 2 6 1 2 7 3654810.031 10675015.13 22674217.19 25468294.88 3 5 6 6 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;nucleus DNA binding;protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 11991 ENSMUSG00000000568.15 Hnrnpd 5 mRNA Splicing - Major Pathway; AUF1 (hnRNP D0) binds and destabilizes mRNA 5 High Q8K2B3 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Mus musculus OX=10090 GN=Sdha PE=1 SV=1" 0 9.64 13 7 9 7 664 72.5 7.37 2 1 1 5 2 1 1 5 5554051.594 5201511.906 5706790.359 6387481.813 7 7 7 6 metabolic process;transport membrane;mitochondrion catalytic activity;nucleotide binding "Pf00890, Pf02910" 66945 ENSMUSG00000021577.13 Sdha 13 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Carbon metabolism 0 High P15105 Glutamine synthetase OS=Mus musculus OX=10090 GN=Glul PE=1 SV=6 0 6.58 10 3 9 3 373 42.1 7.08 1 3 2 2 1 3 3 2 10139889.06 4702256.313 5866441 3521704.906 3 3 3 3 Met-loss+Acetyl [N-Term] cell communication;cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;endoplasmic reticulum;mitochondrion;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00120, Pf03951" 14645 ENSMUSG00000026473.15 Glul 1 Astrocytic Glutamate-Glutamine Uptake And Metabolism; Amino acid synthesis and interconversion (transamination) "GABAergic synapse; Metabolic pathways; Nitrogen metabolism; Biosynthesis of amino acids; Glutamatergic synapse; Alanine, aspartate and glutamate metabolism; Arginine biosynthesis; Glyoxylate and dicarboxylate metabolism" 0 High Q3ULD5 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Mus musculus OX=10090 GN=Mccc2 PE=1 SV=1" 0 13.508 16 8 9 8 563 61.3 8 1 1 7 1 1 7 5332601.531 2985112.328 2051077.75 7158969.453 8 8 7 8 metabolic process mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf01039, Pf03255" 78038 ENSMUSG00000021646.8 Mccc2 13 Biotin transport and metabolism; Branched-chain amino acid catabolism "Valine, leucine and isoleucine degradation; Metabolic pathways" 0 High Q9EQ20 "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Mus musculus OX=10090 GN=Aldh6a1 PE=1 SV=1" 0 6.761 7 4 9 4 535 57.9 8.07 1 1 4 2 2 5 1122221.219 1277748.75 828657.0313 2069890.875 3 3 3 3 cell differentiation;metabolic process mitochondrion catalytic activity;RNA binding Pf00171 104776 ENSMUSG00000021238.10 Aldh6a1 12 Branched-chain amino acid catabolism "Valine, leucine and isoleucine degradation; Metabolic pathways; beta-Alanine metabolism; Propanoate metabolism; Inositol phosphate metabolism; Carbon metabolism" 0 High Q925I1 ATPase family AAA domain-containing protein 3 OS=Mus musculus OX=10090 GN=Atad3 PE=1 SV=1 0 16.383 13 6 9 6 591 66.7 9.29 1 6 1 8 527999.9063 827845.4766 1995658.457 5583292.656 4 5 6 6 cell growth;regulation of biological process membrane;mitochondrion catalytic activity;nucleotide binding;RNA binding "Pf00004, Pf00910, Pf01078, Pf05707, Pf06745, Pf07728, Pf12037, Pf13207, Pf13401" 108888 ENSMUSG00000029036.18 Atad3a 4 Neutrophil degranulation 0 High Q5SWU9 Acetyl-CoA carboxylase 1 OS=Mus musculus OX=10090 GN=Acaca PE=1 SV=1 0 11.917 4 7 9 7 2345 265.1 6.39 2 7 2 7 909328.7656 4102046.688 3043213.328 3730875.375 6 7 7 7 cell organization and biogenesis;metabolic process;response to stimulus cytoplasm;cytoskeleton;cytosol;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00289, Pf00364, Pf01039, Pf02222, Pf02655, Pf02785, Pf02786, Pf07478, Pf08326, Pf13535, Pf15632" 107476 ENSMUSG00000020532.18 Acaca 11 ChREBP activates metabolic gene expression; Biotin transport and metabolism; Fatty acyl-CoA biosynthesis; Import of palmitoyl-CoA into the mitochondrial matrix Fatty acid metabolism; Pyruvate metabolism; Insulin signaling pathway; Metabolic pathways; Propanoate metabolism; AMPK signaling pathway; Fatty acid biosynthesis; Glucagon signaling pathway 0 High P63038 "60 kDa heat shock protein, mitochondrial OS=Mus musculus OX=10090 GN=Hspd1 PE=1 SV=1" 0 14.408 13 7 9 7 573 60.9 6.18 2 7 2 7 987686.9453 2314403.805 2989477.75 6507210.375 5 7 7 7 cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;cytosol;endoplasmic reticulum;endosome;Golgi;membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding;protein binding;RNA binding Pf00118 15510 ENSMUSG00000025980.14 Hspd1 1 RNA degradation; Tuberculosis; Legionellosis; Type I diabetes mellitus 0 High O54724 Caveolae-associated protein 1 OS=Mus musculus OX=10090 GN=Cavin1 PE=1 SV=1 0 12.124 14 5 9 5 392 43.9 5.52 1 5 2 1 6 2 2619714.578 12689571.13 3194953.938 1590777.469 4 5 5 4 metabolic process;regulation of biological process cytoplasm;cytosol;endoplasmic reticulum;membrane;mitochondrion;nucleus protein binding;RNA binding Pf15237 19285 ENSMUSG00000004044.9 Ptrf; Cavin1 11 RNA Polymerase I Transcription Termination 0 High Q8BMF4 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Mus musculus OX=10090 GN=Dlat PE=1 SV=2" 0 6.294 10 4 8 4 642 67.9 8.57 4 1 7 1 11943629.75 3672020.484 4219688.469 1450877.297 4 4 4 4 metabolic process mitochondrion;organelle lumen catalytic activity;protein binding "Pf00198, Pf00364, Pf02817" 235339 ENSMUSG00000000168.9 Dlat 9 Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Glyoxylate metabolism and glycine degradation Pyruvate metabolism; Citrate cycle (TCA cycle); Metabolic pathways; Glycolysis / Gluconeogenesis; Carbon metabolism 0 High Q03265 "ATP synthase subunit alpha, mitochondrial OS=Mus musculus OX=10090 GN=Atp5f1a PE=1 SV=1" 0 10.02 12 6 8 6 553 59.7 9.19 1 6 1 7 641079.7188 486095.5938 715103.4922 4052847.094 5 5 5 5 metabolic process;regulation of biological process;transport membrane;mitochondrion catalytic activity;nucleotide binding;protein binding;RNA binding;transporter activity "Pf00006, Pf00306, Pf02663, Pf02874, Pf05943" 11946 ENSMUSG00000025428.15 Atp5a1 18 Cristae formation; Formation of ATP by chemiosmotic coupling Metabolic pathways; Huntington's disease; Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High Q9Z2T6 "Keratin, type II cuticular Hb5 OS=Mus musculus OX=10090 GN=Krt85 PE=1 SV=2" 0 6.794 7 4 8 3 507 55.7 6.42 1 4 1 1 6 1 152772.6406 5861237.375 1972.640869 1 3 1 structural molecule activity Pf00038 53622 Krt85 15 0 High P07724 Serum albumin OS=Mus musculus OX=10090 GN=Alb PE=1 SV=3 0 5.15 5 3 8 3 608 68.6 6.07 2 2 3 1 2 2 3 1 2229562.813 2107964.563 2178053.188 1721758.063 3 3 3 3 cell communication;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;extracellular;Golgi;nucleus DNA binding;metal ion binding;protein binding Pf00273 11657 ENSMUSG00000029368.10 Alb 5 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Recycling of bile acids and salts; Platelet degranulation ; Transport of organic anions; HDL remodeling; Scavenging of heme from plasma Thyroid hormone synthesis 0 High Q9CR57 60S ribosomal protein L14 OS=Mus musculus OX=10090 GN=Rpl14 PE=1 SV=3 0 4.262 12 2 8 2 217 23.5 11.02 1 1 1 2 2 2 1 3 1225255 1499813.75 979520.8125 1310081.078 2 2 2 2 metabolic process membrane;ribosome protein binding;RNA binding;structural molecule activity Pf01929 67115 ENSMUSG00000025794.9 Rpl14 9 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q61765 "Keratin, type I cuticular Ha1 OS=Mus musculus OX=10090 GN=Krt31 PE=1 SV=2" 0 10.054 14 6 8 4 416 47.1 4.89 6 1 7 1 38408.80469 7498890.938 88455.25098 1 5 2 catalytic activity;motor activity;structural molecule activity "Pf00038, Pf01576, Pf13514" 16660 ENSMUSG00000048981.1 Krt31 11 Formation of the cornified envelope 1 High P14106 Complement C1q subcomponent subunit B OS=Mus musculus OX=10090 GN=C1qb PE=1 SV=2 0 7.015 14 3 8 3 253 26.7 8.15 2 1 3 2 2 4 7894275.5 2054104.469 2704875.156 6240308.063 3 3 3 3 defense response;metabolic process;regulation of biological process;response to stimulus extracellular;membrane protein binding "Pf00229, Pf00386" 12260 ENSMUSG00000036905.8 C1qb 4 Regulation of Complement cascade; Classical antibody-mediated complement activation Chagas disease (American trypanosomiasis); Staphylococcus aureus infection; Complement and coagulation cascades; Pertussis; Prion diseases; Systemic lupus erythematosus 0 High Q8VCM7 Fibrinogen gamma chain OS=Mus musculus OX=10090 GN=Fgg PE=1 SV=1 0 7.692 12 4 8 4 436 49.4 5.86 1 3 2 2 1 3 2 2 2661503.563 2701050.219 1790391.5 1352951.984 4 4 2 4 cell organization and biogenesis;coagulation;defense response;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;extracellular metal ion binding;protein binding;structural molecule activity "Pf00147, Pf08702" 99571 ENSMUSG00000033860.13 Fgg 3 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); p130Cas linkage to MAPK signaling for integrins; Post-translational protein phosphorylation; Integrin cell surface interactions; Regulation of TLR by endogenous ligand; Common Pathway of Fibrin Clot Formation; GRB2:SOS provides linkage to MAPK signaling for Integrins ; Platelet degranulation Staphylococcus aureus infection; Platelet activation; Complement and coagulation cascades 0 High A8DUK4 Beta-globin OS=Mus musculus OX=10090 GN=Hbb-bs PE=1 SV=1 0 8.408 32 4 8 4 147 15.7 7.69 1 2 4 1 1 2 4 1 4475025.75 5655590.188 5304578.313 2784631.063 4 4 4 4 regulation of biological process;transport antioxidant activity;catalytic activity;metal ion binding;protein binding;transporter activity Pf00042 100503605; 101488143; 15129 ENSMUSG00000073940.3; ENSMUSG00000052305.6 Beta-s; Hbb-bs; Hbb-bt; Hbb-b1 7 Erythrocytes take up carbon dioxide and release oxygen; Neutrophil degranulation; Factors involved in megakaryocyte development and platelet production; Erythrocytes take up oxygen and release carbon dioxide; Scavenging of heme from plasma African trypanosomiasis; Malaria 0 High Q8QZT1 "Acetyl-CoA acetyltransferase, mitochondrial OS=Mus musculus OX=10090 GN=Acat1 PE=1 SV=1" 0 7.93 11 5 7 5 424 44.8 8.51 5 1 6 1 1172695.156 10044495.81 2455341.281 1505947.563 3 5 3 3 cell organization and biogenesis;metabolic process;response to stimulus membrane;mitochondrion;organelle lumen catalytic activity;metal ion binding;protein binding "Pf00108, Pf00109, Pf02803" 110446 ENSMUSG00000032047.5 Acat1 9 Synthesis of Ketone Bodies; Utilization of Ketone Bodies; Branched-chain amino acid catabolism "Fatty acid metabolism; Pyruvate metabolism; Tryptophan metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Terpenoid backbone biosynthesis; Lysine degradation; Fatty acid degradation; Butanoate metabolism; Propanoate metabolism; Synthesis and degradation of ketone bodies; Carbon metabolism; Glyoxylate and dicarboxylate metabolism" 0 High P11152 Lipoprotein lipase OS=Mus musculus OX=10090 GN=Lpl PE=1 SV=3 0 11.044 10 5 7 5 474 53.1 7.87 5 7 186943.3047 735284.9805 177433.0117 12563643.97 2 4 2 6 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cell surface;extracellular;membrane catalytic activity;protein binding "Pf00151, Pf01477, Pf12695, Pf12697" 16956 ENSMUSG00000015568.16 Lpl 8 Assembly of active LPL and LIPC lipase complexes; Chylomicron remodeling; Signaling by GPCR; Retinoid metabolism and transport PPAR signaling pathway; Alzheimer's disease; Glycerolipid metabolism 0 High Q99MR8 "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial OS=Mus musculus OX=10090 GN=Mccc1 PE=1 SV=2" 0 7.74 7 4 7 4 717 79.3 7.83 2 4 2 5 2425183.969 1881995.359 1944178.234 3557563.125 3 4 4 4 metabolic process membrane;mitochondrion;organelle lumen catalytic activity;metal ion binding;nucleotide binding "Pf00289, Pf00364, Pf01071, Pf02222, Pf02785, Pf02786, Pf07478, Pf13533, Pf13535, Pf15632" 72039 ENSMUSG00000027709.9 Mccc1 3 Biotin transport and metabolism; Branched-chain amino acid catabolism "Valine, leucine and isoleucine degradation; Metabolic pathways" 0 High Q80XR6 Heterogeneous nuclear ribonucleoprotein A/B OS=Mus musculus OX=10090 GN=Hnrnpab PE=1 SV=1 0 4.139 6 2 7 1 311 33.8 5.83 1 1 2 1 3 3 372396.25 446195.2813 1 1 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;nucleus DNA binding;protein binding;RNA binding "Pf00076, Pf08143, Pf13893, Pf14259" 15384 ENSMUSG00000020358.17 Hnrnpab 11 0 High P83741 Serine/threonine-protein kinase WNK1 OS=Mus musculus OX=10090 GN=Wnk1 PE=1 SV=2 0 6.454 2 4 7 4 2377 250.8 6.43 2 3 2 2 3 2 28212.52344 1900829.156 2617385.438 935311.5938 1 4 4 3 metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;membrane catalytic activity;enzyme regulator activity;metal ion binding;nucleotide binding;protein binding "Pf00069, Pf07714, Pf09770, Pf12202" 232341 ENSMUSG00000045962.16 Wnk1 6 Stimuli-sensing channels 0 High Q6P5H2 Nestin OS=Mus musculus OX=10090 GN=Nes PE=1 SV=1 0.013 1.542 0 1 6 1 1864 207 4.34 1 1 1 1 2 3 22260636 18303594 9912472 22824746 1 1 1 1 cell organization and biogenesis;cell proliferation;development;regulation of biological process cytoplasm;cytoskeleton protein binding;structural molecule activity "Pf00038, Pf02463" 18008 ENSMUSG00000004891.16 Nes 3 0 High Q02105 Complement C1q subcomponent subunit C OS=Mus musculus OX=10090 GN=C1qc PE=1 SV=2 0 4.966 13 3 6 3 246 26 8.54 2 2 2 2 2 2 11415725.5 3386121.813 4075212.5 8055846.625 3 3 3 3 defense response;metabolic process;regulation of biological process;response to stimulus extracellular;membrane protein binding "Pf00229, Pf00386, Pf01391" 12262 ENSMUSG00000036896.5 C1qc 4 Regulation of Complement cascade; Classical antibody-mediated complement activation Chagas disease (American trypanosomiasis); Staphylococcus aureus infection; Complement and coagulation cascades; Pertussis; Prion diseases; Systemic lupus erythematosus 0 High P19324 Serpin H1 OS=Mus musculus OX=10090 GN=Serpinh1 PE=1 SV=3 0 9.31 12 4 6 4 417 46.5 8.82 4 6 844335.0625 1193752.094 4556360.688 4 4 4 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;endoplasmic reticulum;membrane;organelle lumen enzyme regulator activity;protein binding;RNA binding Pf00079 12406 ENSMUSG00000070436.12 Serpinh1 7 Collagen biosynthesis and modifying enzymes 0 High Q91VT8 Small integral membrane protein 14 OS=Mus musculus OX=10090 GN=Smim14 PE=1 SV=1 0 15.346 43 2 6 2 99 10.7 5.73 2 6 56475.46875 332006.375 24504412.25 1 2 3 Met-loss [N-Term]; Met-loss+Acetyl [N-Term] endoplasmic reticulum;membrane Pf11027 68552 ENSMUSG00000037822.12 1110003E01Rik; Smim14 5 0 High A6BLY7 "Keratin, type I cytoskeletal 28 OS=Mus musculus OX=10090 GN=Krt28 PE=1 SV=1" 0 3.632 3 2 6 1 462 50.3 5.29 1 2 2 1 3 2 15561076 19301186 8151964.5 34193640 1 1 1 1 cytoplasm structural molecule activity Pf00038 70843 ENSMUSG00000055937.1 Krt28 11 Formation of the cornified envelope 0 High Q9CQA3 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Mus musculus OX=10090 GN=Sdhb PE=1 SV=1" 0 12.046 19 5 6 5 282 31.8 8.68 1 4 1 5 1481087.875 2746118.797 1964738.672 4874620.859 4 5 5 5 metabolic process;transport membrane;mitochondrion catalytic activity;metal ion binding "Pf13085, Pf13183, Pf13534" 67680 ENSMUSG00000009863.14 Sdhb 4 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Carbon metabolism 0 High H9KV15 Protein SON OS=Mus musculus OX=10090 GN=Son PE=1 SV=1 0 7.377 3 5 6 5 2343 253.9 5.4 1 5 1 5 1881815.094 1844740.844 2386440.781 5 4 5 cell organization and biogenesis;metabolic process;regulation of biological process nucleus DNA binding;protein binding;RNA binding 20658 ENSMUSG00000022961.17 Son 16 0 High P61358 60S ribosomal protein L27 OS=Mus musculus OX=10090 GN=Rpl27 PE=1 SV=2 0 4.714 18 3 6 3 136 15.8 10.56 3 3 3 3 410158.4766 1719468.438 985296.3438 960013.25 2 2 2 2 metabolic process membrane;nucleus;ribosome RNA binding;structural molecule activity "Pf00467, Pf01777" 19942; 108167922 ENSMUSG00000063316.13; ENSMUSG00000073640.2 Rpl27; LOC108167922 11; 18 Ribosome 0 High Q80X19 Collagen alpha-1(XIV) chain OS=Mus musculus OX=10090 GN=Col14a1 PE=1 SV=2 0 5.444 2 4 6 4 1797 192.9 5.1 2 1 3 2 1 3 1921202.531 1436245.625 2060290.805 938269.8906 4 4 4 4 cell organization and biogenesis;regulation of biological process extracellular protein binding;RNA binding "Pf00041, Pf00092, Pf01391, Pf13519" 12818 ENSMUSG00000022371.15 Col14a1 15 Collagen chain trimerization; Assembly of collagen fibrils and other multimeric structures 0 High Q9EQK5 Major vault protein OS=Mus musculus OX=10090 GN=Mvp PE=1 SV=4 0 3.896 3 3 5 3 861 95.9 5.59 2 1 2 2 1 2 2932375.688 1364802.375 2109104.219 910091.4688 3 3 3 3 cell proliferation;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;nucleus protein binding "Pf01145, Pf01505, Pf11978" 78388 Mvp 7 0 High Q9D9P1 MICOS complex subunit OS=Mus musculus OX=10090 GN=Chchd3 PE=1 SV=1 0 5.581 14 3 5 3 175 20.4 8.27 1 1 3 1 1 3 2447494.375 602569.9063 1141519.813 2887266.281 2 2 3 3 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;membrane;mitochondrion;nucleus protein binding;structural molecule activity Pf05300 66075 ENSMUSG00000053768.13 Chchd3 6 0 High P62918 60S ribosomal protein L8 OS=Mus musculus OX=10090 GN=Rpl8 PE=1 SV=2 0 3.398 11 2 5 2 257 28 11.03 1 2 1 2 2 1 1179383.063 1906525.438 1626130.375 1623334.906 2 2 2 2 metabolic process;response to stimulus cytoplasm;membrane;ribosome protein binding;RNA binding;structural molecule activity "Pf00181, Pf03947" 26961 ENSMUSG00000003970.8 Rpl8 15 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High O35206 Collagen alpha-1(XV) chain OS=Mus musculus OX=10090 GN=Col15a1 PE=1 SV=2 0 4.842 3 3 5 3 1367 140.4 4.89 2 3 2 3 2065086.969 1027051.047 800844.1563 779234.4336 2 2 2 3 extracellular structural molecule activity "Pf01391, Pf06482, Pf13385" 12819 ENSMUSG00000028339.17 Col15a1 4 Collagen chain trimerization; Collagen degradation Protein digestion and absorption 0 High A0A0R4J083 "Long-chain-specific acyl-CoA dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Acadl PE=1 SV=1" 0 5.39 5 3 5 3 430 47.9 8.15 2 1 2 2 1 2 2566988.844 1430085.531 1011493.469 1939612.688 3 3 2 3 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf00441, Pf02770, Pf02771, Pf08028" 11363 ENSMUSG00000026003.5 Acadl 1 Beta oxidation of myristoyl-CoA to lauroyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA PPAR signaling pathway; Fatty acid metabolism; Metabolic pathways; Fatty acid degradation 0 High P62889 60S ribosomal protein L30 OS=Mus musculus OX=10090 GN=Rpl30 PE=1 SV=2 0 3.916 27 2 5 2 115 12.8 9.63 1 1 2 1 2 2 784973.3594 840533.9375 551792.4375 1018176.344 2 1 1 2 defense response;metabolic process;response to stimulus membrane;nucleus;ribosome RNA binding;structural molecule activity Pf01248 19946; 667779; 666899 ENSMUSG00000058600.13 Rpl30; Rpl30-ps8; Gm12191 15; 12; 11 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q9DCD0 "6-phosphogluconate dehydrogenase, decarboxylating OS=Mus musculus OX=10090 GN=Pgd PE=1 SV=3" 0 8.568 10 5 5 5 483 53.2 7.23 5 5 171607.0977 169421.252 2509989.969 4 4 5 metabolic process cytoplasm;nucleus catalytic activity;nucleotide binding "Pf00393, Pf03446" 110208 ENSMUSG00000028961.15 Pgd 4 Pentose phosphate pathway (hexose monophosphate shunt) Glutathione metabolism; Metabolic pathways; Pentose phosphate pathway; Carbon metabolism 0 High Q3TML0 Protein disulfide-isomerase A6 OS=Mus musculus OX=10090 GN=Pdia6 PE=1 SV=1 0 11.142 16 5 5 5 445 48.7 5.19 5 5 28545.8457 297337.0547 24738.66602 5991566.688 1 2 1 5 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytosol;endoplasmic reticulum;membrane;organelle lumen catalytic activity "Pf00085, Pf13098, Pf13848, Pf13899, Pf13905" 71853 ENSMUSG00000020571.12 Pdia6 12 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation Protein processing in endoplasmic reticulum 0 High Q64475 Histone H2B type 1-B OS=Mus musculus OX=10090 GN=H2bc3 PE=1 SV=3 0 5.001 21 3 5 3 126 13.9 10.32 2 1 1 2 1 2 1222654.938 3863437.75 2210334.875 1612041.344 2 3 3 3 cell organization and biogenesis chromosome;cytosol;nucleus DNA binding;protein binding "Pf00125, Pf00808" 319178 ENSMUSG00000075031.3 Hist1h2bb 13 HATs acetylate histones; E3 ubiquitin ligases ubiquitinate target proteins; Meiotic Recombination; Mus musculus biological processes; NoRC negatively regulates rRNA expression; Meiotic Synapsis Alcoholism; Systemic lupus erythematosus; Viral carcinogenesis 0 High P62754 40S ribosomal protein S6 OS=Mus musculus OX=10090 GN=Rps6 PE=1 SV=1 0 3.297 9 2 5 2 249 28.7 10.84 2 1 3 2 981955.1875 470925.0313 830401.375 1 1 1 cell death;cell differentiation;cell proliferation;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity Pf01092 667739; 20104; 105244208 ENSMUSG00000028495.14 Rps6-ps4; Rps6; LOC105244208 2; 4 mTOR signaling pathway; Ribosome; Insulin signaling pathway; Proteoglycans in cancer; HIF-1 signaling pathway; PI3K-Akt signaling pathway; EGFR tyrosine kinase inhibitor resistance 0 High Q497I4 "Keratin, type I cuticular Ha5 OS=Mus musculus OX=10090 GN=Krt35 PE=1 SV=1" 0 5.183 5 3 5 1 455 50.5 4.97 3 1 4 1 376539 4339643.5 536580.0625 1 1 1 structural molecule activity Pf00038 53617 ENSMUSG00000048013.9 Krt35 11 Formation of the cornified envelope 0 High P14148 60S ribosomal protein L7 OS=Mus musculus OX=10090 GN=Rpl7 PE=1 SV=2 0 2.755 4 1 5 1 270 31.4 10.89 1 1 1 1 2 2 892267.125 1151678.25 687139.3125 766105.125 1 1 1 1 metabolic process cytoplasm;membrane;nucleus;ribosome DNA binding;protein binding;RNA binding;structural molecule activity "Pf00327, Pf08079" 19989 ENSMUSG00000043716.13 Rpl7 1 Ribosome 0 High P42125 "Enoyl-CoA delta isomerase 1, mitochondrial OS=Mus musculus OX=10090 GN=Eci1 PE=1 SV=2" 0 6.602 17 4 5 4 289 32.2 8.98 2 3 2 3 1627716.766 2317150.719 2467418.625 3514377.625 4 4 4 4 metabolic process membrane;mitochondrion;organelle lumen catalytic activity;protein binding Pf00378 13177 ENSMUSG00000024132.5 Eci1 17 mitochondrial fatty acid beta-oxidation of unsaturated fatty acids Fatty acid degradation 0 High B8JK33 Heterogeneous nuclear ribonucleoprotein M OS=Mus musculus OX=10090 GN=Hnrnpm PE=1 SV=1 0 11.271 10 5 5 5 640 68.1 8.32 5 5 1069267.078 1717055.156 3196591.844 4 4 5 metabolic process;regulation of biological process cell surface;membrane;nucleus;spliceosomal complex protein binding;RNA binding "Pf00076, Pf11532, Pf13893, Pf14259" 76936 ENSMUSG00000059208.14 Hnrnpm 17 0 High E9QNN1 ATP-dependent RNA helicase A OS=Mus musculus OX=10090 GN=Dhx9 PE=1 SV=1 0 4.354 2 2 5 2 1384 149.6 6.83 2 2 1 2 2 1 1773232 1083648.219 405489.25 625983.5313 2 2 1 2 cell death;cell differentiation;cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;membrane;nucleus;ribosome catalytic activity;DNA binding;metal ion binding;nucleotide binding;protein binding;RNA binding "Pf00035, Pf00270, Pf00271, Pf04408, Pf07717" 13211 ENSMUSG00000042699.11 Dhx9 1 DEx/H-box helicases activate type I IFN and inflammatory cytokines production ; Activated TLR4 signalling; mRNA Splicing - Major Pathway; TAK1 activates NFkB by phosphorylation and activation of IKKs complex; RIP-mediated NFkB activation via ZBP1; TRAF6 mediated NF-kB activation; Interleukin-1 family signaling 0 High Q9CR68 "Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Mus musculus OX=10090 GN=Uqcrfs1 PE=1 SV=1" 0 3.554 9 3 5 3 274 29.3 8.7 1 1 2 1 1 3 869970.0781 821910.3906 833581.7188 1511316.297 3 3 3 3 metabolic process;response to stimulus;transport membrane;mitochondrion catalytic activity;metal ion binding;protein binding;transporter activity "Pf00355, Pf02921, Pf09165" 66694 ENSMUSG00000038462.3 Uqcrfs1 13 Respiratory electron transport Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 High Q60936 "Atypical kinase COQ8A, mitochondrial OS=Mus musculus OX=10090 GN=Coq8a PE=1 SV=2" 0 9.675 11 5 5 5 645 71.7 6.54 5 5 872823.7266 834641.0859 971424.8008 4544582.813 3 3 4 5 metabolic process membrane;mitochondrion catalytic activity;nucleotide binding Pf03109 67426 ENSMUSG00000026489.13 Adck3; Coq8a 1 0 High P10126 Elongation factor 1-alpha 1 OS=Mus musculus OX=10090 GN=Eef1a1 PE=1 SV=3 0 5.098 6 3 5 3 462 50.1 9.01 2 3 2 3 3045250.563 3136095.344 2485398.688 2938701.313 3 3 3 3 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;nucleus catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00009, Pf03143, Pf03144" 13627 ENSMUSG00000037742.14 Eef1a1; LOC101056619 9 Legionellosis; RNA transport 0 High P62830 60S ribosomal protein L23 OS=Mus musculus OX=10090 GN=Rpl23 PE=1 SV=1 0 3.71 11 2 4 2 140 14.9 10.51 2 4 191391.4531 766911.7422 413233.5 1945397.406 1 2 2 2 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;ribosome protein binding;RNA binding;structural molecule activity Pf00238 65019; 100044627; 100862455 ENSMUSG00000071415.6 Rpl23; LOC100044627; LOC100862455 11; 17 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High O08749 "Dihydrolipoyl dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Dld PE=1 SV=2" 0 5.363 5 3 4 3 509 54.2 7.9 3 4 491282.9844 269491.2344 287201.3906 1765865.969 3 2 2 3 cellular homeostasis;metabolic process;regulation of biological process mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf00070, Pf00890, Pf01134, Pf01946, Pf02852, Pf03486, Pf07992, Pf12831, Pf13450" 13382 ENSMUSG00000020664.10 Dld 12 Glycine degradation; Signaling by Retinoic Acid; Citric acid cycle (TCA cycle); Lysine catabolism; Regulation of pyruvate dehydrogenase (PDH) complex; Branched-chain amino acid catabolism "Pyruvate metabolism; Citrate cycle (TCA cycle); Valine, leucine and isoleucine degradation; Metabolic pathways; Glycine, serine and threonine metabolism; Glycolysis / Gluconeogenesis; Propanoate metabolism; Carbon metabolism; Glyoxylate and dicarboxylate metabolism" 0 High Q7SIG6 "Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 OS=Mus musculus OX=10090 GN=Asap2 PE=1 SV=3" 0.009 1.632 1 1 4 1 958 106.7 6.65 1 1 1 1 1 2 36200784 59261220 36119460 44977868 1 1 1 1 regulation of biological process cytoplasm;Golgi;membrane enzyme regulator activity;metal ion binding;protein binding "Pf00018, Pf00023, Pf00169, Pf01412, Pf07653, Pf12796, Pf13637, Pf13857, Pf14604" 211914 ENSMUSG00000052632.15 Asap2 12 Endocytosis; Fc gamma R-mediated phagocytosis 0 High Q99M87 "DnaJ homolog subfamily A member 3, mitochondrial OS=Mus musculus OX=10090 GN=Dnaja3 PE=1 SV=1" 0 6.391 8 3 4 3 480 52.4 9.22 3 4 318039.3594 629707.8594 757379.3594 2976910.313 2 3 3 3 cell death;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus;organelle lumen enzyme regulator activity;metal ion binding;nucleotide binding;protein binding "Pf00226, Pf00684, Pf01556" 83945 ENSMUSG00000004069.16 Dnaja3 16 Viral carcinogenesis 0 High Q9CQ62 "2,4-dienoyl-CoA reductase, mitochondrial OS=Mus musculus OX=10090 GN=Decr1 PE=1 SV=1" 0 7.611 16 4 4 4 335 36.2 8.95 4 4 1194383.859 1323971.547 1052010.297 2674436.375 3 4 3 4 cell organization and biogenesis;metabolic process cytosol;mitochondrion;nucleus catalytic activity;nucleotide binding "Pf00106, Pf08659, Pf13561" 67460 ENSMUSG00000028223.8 Decr1 4 mitochondrial fatty acid beta-oxidation of unsaturated fatty acids 0 High P70404 "Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial OS=Mus musculus OX=10090 GN=Idh3g PE=1 SV=1" 0 4.585 5 2 4 2 393 42.8 9.01 1 2 1 3 949429.8125 1150841.781 955459.3438 2634844.188 2 2 2 2 metabolic process;regulation of biological process mitochondrion catalytic activity;metal ion binding;nucleotide binding Pf00180 15929 ENSMUSG00000002010.17 Idh3g X Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Biosynthesis of amino acids; 2-Oxocarboxylic acid metabolism; Carbon metabolism 0 High P01837 Immunoglobulin kappa constant OS=Mus musculus OX=10090 GN=Igkc PE=1 SV=2 0 3.897 10 1 4 1 107 11.9 5.9 1 1 1 1 1 1 1 1 6063568.5 6775779 4005312.25 8284304.5 1 1 1 1 0 High Q9Z204 Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Mus musculus OX=10090 GN=Hnrnpc PE=1 SV=1 0 4.49 10 3 4 3 313 34.4 5.05 2 1 1 2 1 1 507831.3281 1653607.969 1113830.906 1062710.125 2 3 3 3 Met-loss+Acetyl [N-Term] cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process cytoskeleton;cytosol;extracellular;membrane;nucleus;spliceosomal complex DNA binding;enzyme regulator activity;protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 15381 ENSMUSG00000060373.14 Hnrnpc 14 mRNA Splicing - Major Pathway; SUMOylation of RNA binding proteins Spliceosome 0 High P35441 Thrombospondin-1 OS=Mus musculus OX=10090 GN=Thbs1 PE=1 SV=1 0 6.954 4 4 4 4 1170 129.6 4.96 4 4 568568.5 2115916.469 2 3 cell organization and biogenesis;cellular component movement;defense response;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;endoplasmic reticulum;extracellular metal ion binding;protein binding "Pf00090, Pf00093, Pf02210, Pf02412, Pf05735, Pf12947, Pf14828" 21825 Thbs1 2 0 High Q8C2Q8 ATP synthase subunit gamma OS=Mus musculus OX=10090 GN=Atp5c1 PE=1 SV=1 0 7.809 16 4 4 4 274 30.2 8.84 4 4 425838.2891 609216.9063 698311.125 3100498.469 3 4 4 4 metabolic process;transport membrane;mitochondrion catalytic activity;RNA binding;transporter activity Pf00231 11949 ENSMUSG00000025781.14 Atp5c1 2 0 High P01898 "H-2 class I histocompatibility antigen, Q10 alpha chain OS=Mus musculus OX=10090 GN=H2-Q10 PE=1 SV=3" 0 8.79 16 4 4 4 325 37.2 5.25 4 4 59900.79688 2514271.719 1 3 cell surface;endoplasmic reticulum;Golgi;membrane protein binding;RNA binding "Pf00129, Pf07654, Pf08205" 15007 ENSMUSG00000067235.14 H2-Q10 17 Endocytosis; Herpes simplex infection; Allograft rejection; Epstein-Barr virus infection; Cell adhesion molecules (CAMs); HTLV-I infection; Phagosome; Graft-versus-host disease; Viral myocarditis; Antigen processing and presentation; Type I diabetes mellitus; Autoimmune thyroid disease; Viral carcinogenesis 0 High Q9D023 Mitochondrial pyruvate carrier 2 OS=Mus musculus OX=10090 GN=Mpc2 PE=1 SV=1 0 3.61 16 3 4 3 127 14.3 10.61 3 4 186768.4688 408159.6094 569354.6563 2883340.031 2 3 2 3 regulation of biological process;transport membrane;mitochondrion;nucleus transporter activity Pf03650 70456 ENSMUSG00000026568.6 Mpc2 1 0 High Q8VCT4 Carboxylesterase 1D OS=Mus musculus OX=10090 GN=Ces1d PE=1 SV=1 0 5.719 5 3 4 3 565 61.7 6.61 3 4 135617.7422 130223.0313 72056.35938 3117492.313 2 1 1 3 cell differentiation;cell organization and biogenesis;metabolic process;response to stimulus cytoplasm;cytosol;endoplasmic reticulum;organelle lumen catalytic activity "Pf00135, Pf00326, Pf00756, Pf07859, Pf12695" 104158 ENSMUSG00000056973.6 Ces1d 8 Phase I - Functionalization of compounds Metabolic pathways; Drug metabolism - other enzymes 0 High Q921W0 Charged multivesicular body protein 1a OS=Mus musculus OX=10090 GN=Chmp1a PE=1 SV=1 0 3.353 13 3 4 3 196 21.6 8.06 2 2 2 2 2033918.25 2743304.75 460549.2813 3 3 3 cell communication;cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport chromosome;cytoplasm;endosome;membrane;nucleus protein binding Pf03357 234852 ENSMUSG00000000743.9 Chmp1a 8 Endocytosis 0 High P86048 60S ribosomal protein L10-like OS=Mus musculus OX=10090 GN=Rpl10l PE=2 SV=1 0 3.796 15 3 4 3 214 24.5 10.11 1 1 1 1 2 1 1385249.531 2464798.25 1178331.031 1336719.188 3 3 3 3 cell organization and biogenesis;metabolic process membrane;nucleus;ribosome RNA binding;structural molecule activity Pf00252 238217 ENSMUSG00000060499.7 Rpl10l 12 0 High Q9D051 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Mus musculus OX=10090 GN=Pdhb PE=1 SV=1" 0 4.08 6 2 4 2 359 38.9 6.87 1 1 2 1 1 2 602453.625 354452.1094 350519.6094 2018588.938 1 2 2 2 metabolic process mitochondrion;nucleus;organelle lumen catalytic activity "Pf02779, Pf02780" 68263 ENSMUSG00000021748.8 Pdhb 14 Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Glyoxylate metabolism and glycine degradation Pyruvate metabolism; Citrate cycle (TCA cycle); Metabolic pathways; Glycolysis / Gluconeogenesis; HIF-1 signaling pathway; Carbon metabolism; Central carbon metabolism in cancer; Glucagon signaling pathway 0 High Q9D8L3 "Signal sequence receptor, delta OS=Mus musculus OX=10090 GN=Ssr4 PE=1 SV=1" 0 7.568 20 3 4 3 173 19 5.78 3 4 15724.36914 3419068.438 1 3 endoplasmic reticulum;membrane Pf05404 20832 ENSMUSG00000002014.12 Ssr4 X 0 High Q9CZU6 "Citrate synthase, mitochondrial OS=Mus musculus OX=10090 GN=Cs PE=1 SV=1" 0 2.958 4 2 4 2 464 51.7 8.57 1 1 2 1 1 2 738656 1247406.75 1292686.063 1366878.563 2 2 2 2 metabolic process mitochondrion;nucleus;organelle lumen catalytic activity;RNA binding Pf00285 12974 ENSMUSG00000005683.8 Cs 10 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Biosynthesis of amino acids; 2-Oxocarboxylic acid metabolism; Carbon metabolism; Glyoxylate and dicarboxylate metabolism 0 High O54988 STE20-like serine/threonine-protein kinase OS=Mus musculus OX=10090 GN=Slk PE=1 SV=2 0.011 1.261 1 1 4 1 1233 141.4 5.14 1 1 1 1 1 2 507330503.8 456432431.1 118669408.8 380699566.8 1 1 1 1 cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm catalytic activity;nucleotide binding;protein binding "Pf00069, Pf07714, Pf12474, Pf14531" 20874 ENSMUSG00000025060.14 Slk 19 Oocyte meiosis 0 High P35700 Peroxiredoxin-1 OS=Mus musculus OX=10090 GN=Prdx1 PE=1 SV=1 0 2.169 5 1 4 1 199 22.2 8.12 1 1 1 2 1 1 1268438 1248327.875 1066414.5 1302329.5 1 1 1 1 cell proliferation;cellular homeostasis;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;mitochondrion;nucleus;organelle lumen antioxidant activity;catalytic activity;protein binding;RNA binding "Pf00578, Pf08534, Pf10417" 18477 ENSMUSG00000028691.12 Prdx1 4 Detoxification of Reactive Oxygen Species; TP53 Regulates Metabolic Genes Peroxisome 0 High S4R1N6 40S ribosomal protein S18 OS=Mus musculus OX=10090 GN=Rps18 PE=3 SV=1 0 3.406 17 2 4 2 107 12.5 10.13 1 1 2 1 1 2 1171208.344 1774709.438 1859859.875 3139563.625 2 2 2 2 metabolic process ribosome RNA binding;structural molecule activity Pf00416 ENSMUSG00000008668.14 17 0 High Q91VB8 Alpha globin 1 OS=Mus musculus OX=10090 GN=Hba-a1 PE=1 SV=1 0 3.983 25 3 4 3 142 15.1 8.22 2 2 2 2 1697999.844 2470647.656 3174925.406 1944871.516 3 3 3 3 response to stimulus;transport membrane antioxidant activity;catalytic activity;metal ion binding;protein binding;transporter activity Pf00042 15122; 110257 ENSMUSG00000069919.7; ENSMUSG00000069917.7 Hba-a1; Hba-a2 11 Erythrocytes take up carbon dioxide and release oxygen; Erythrocytes take up oxygen and release carbon dioxide; Scavenging of heme from plasma African trypanosomiasis; Malaria 0 High A0A1D5RME4 60S ribosomal protein L18a (Fragment) OS=Mus musculus OX=10090 GN=Rpl18a PE=1 SV=1 0 2.045 7 1 4 1 123 14.4 10.61 1 1 1 1 1 1 1 1 1069233.375 1071382 541402 617249.6875 1 1 1 1 metabolic process ribosome structural molecule activity Pf01775 ENSMUSG00000045128.9 8 0 High C0HK80 Adipocyte-related X-chromosome expressed sequence 2 OS=Mus musculus OX=10090 GN=Arxes2 PE=1 SV=1 0 7.447 22 4 4 4 180 20.1 9.6 4 4 26992.00781 6531021.5 1 4 cell differentiation;metabolic process;transport endoplasmic reticulum;membrane catalytic activity Pf04573 76219; 76976 ENSMUSG00000048040.8; ENSMUSG00000048355.2 Arxes1; Arxes2 X Protein export 0 High O88569 Heterogeneous nuclear ribonucleoproteins A2/B1 OS=Mus musculus OX=10090 GN=Hnrnpa2b1 PE=1 SV=2 0 3.649 6 2 3 2 353 37.4 8.95 1 2 1 2 62338.6875 53253.98438 419652.625 580734.8438 1 1 2 2 cell organization and biogenesis;metabolic process;regulation of biological process;transport chromosome;cytoplasm;extracellular;membrane;nucleus;spliceosomal complex DNA binding;protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 53379 ENSMUSG00000004980.16 Hnrnpa2b1 6 mRNA Splicing - Major Pathway 0 High Q8K0E8 Fibrinogen beta chain OS=Mus musculus OX=10090 GN=Fgb PE=1 SV=1 0 3.994 9 3 3 3 481 54.7 7.08 1 1 1 1 1 1 2364227.75 3297094.188 1969570.438 1610962.375 3 3 3 3 cell organization and biogenesis;coagulation;defense response;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;extracellular protein binding;structural molecule activity "Pf00147, Pf01920, Pf08702" 110135 ENSMUSG00000033831.5 Fgb 3 p130Cas linkage to MAPK signaling for integrins; Integrin cell surface interactions; Regulation of TLR by endogenous ligand; Common Pathway of Fibrin Clot Formation; GRB2:SOS provides linkage to MAPK signaling for Integrins ; Platelet degranulation Platelet activation; Complement and coagulation cascades 0 High E9PWU4 Adiponectin (Fragment) OS=Mus musculus OX=10090 GN=Adipoq PE=1 SV=1 0 2.847 11 2 3 2 168 17.9 6.16 2 3 13652.04102 33781.36328 8190.035645 1544569.656 1 1 1 2 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum protein binding "Pf00386, Pf01391" ENSMUSG00000022878.5 16 0 High P54116 Erythrocyte band 7 integral membrane protein OS=Mus musculus OX=10090 GN=Stom PE=1 SV=3 0 4.791 9 3 3 3 284 31.4 6.93 3 3 987243.625 66330.98438 26613.83594 3326779.875 3 1 1 3 cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton;cytosol;endoplasmic reticulum;membrane;mitochondrion protein binding Pf01145 13830 ENSMUSG00000026880.11 Stom 2 Neutrophil degranulation 0 High P62908 40S ribosomal protein S3 OS=Mus musculus OX=10090 GN=Rps3 PE=1 SV=1 0 4.789 14 3 3 3 243 26.7 9.66 3 3 321184.125 887613.0313 641030.7891 2422840.625 2 3 3 3 cell death;cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;endoplasmic reticulum;membrane;mitochondrion;nucleus;organelle lumen;ribosome catalytic activity;DNA binding;protein binding;RNA binding;structural molecule activity "Pf00189, Pf07650" 27050 ENSMUSG00000030744.13 Rps3 7 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High Q9CZM2 60S ribosomal protein L15 OS=Mus musculus OX=10090 GN=Rpl15 PE=1 SV=4 0 3.676 11 2 3 2 204 24.1 11.62 1 1 1 1 1 1 1015674.328 822342.8125 848961.9688 784890.0625 2 2 2 1 metabolic process membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity Pf00827 66480 ENSMUSG00000012405.15 Rpl15 14 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q8BG05 Heterogeneous nuclear ribonucleoprotein A3 OS=Mus musculus OX=10090 GN=Hnrnpa3 PE=1 SV=1 0 5.281 6 2 3 2 379 39.6 9.01 1 2 1 2 380618.5156 558557.1953 897830.7188 1444408.781 2 2 2 2 metabolic process;transport cytoplasm;nucleus;spliceosomal complex RNA binding;transporter activity "Pf00076, Pf13893, Pf14259" 229279 ENSMUSG00000059005.13 Hnrnpa3 2 Spliceosome 0 High Q91ZE0 "Trimethyllysine dioxygenase, mitochondrial OS=Mus musculus OX=10090 GN=Tmlhe PE=1 SV=2" 0 6.525 5 2 3 2 421 49.6 8.25 2 3 38049.07031 481600.1797 553503.7734 3466787.625 1 2 2 2 metabolic process;regulation of biological process mitochondrion;organelle lumen catalytic activity;metal ion binding "Pf02668, Pf06155" 192289 ENSMUSG00000079834.2 Tmlhe X Carnitine synthesis Lysine degradation 0 High A0A1B0GSS8 60S ribosomal protein L18 OS=Mus musculus OX=10090 GN=Rpl18 PE=1 SV=1 0.01 1.179 6 1 3 1 155 17.9 11.91 1 1 1 1 1 1 261730.25 776210.375 637351.8125 336887.7188 1 1 1 1 metabolic process ribosome structural molecule activity Pf00828 ENSMUSG00000059070.16 7 0 High Q9DBG6 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Mus musculus OX=10090 GN=Rpn2 PE=1 SV=1 0 4.172 5 3 3 3 631 69 5.81 3 3 4056.87915 31830.62305 2009504.938 1 1 3 metabolic process;response to stimulus endoplasmic reticulum;membrane catalytic activity Pf05817 20014 ENSMUSG00000027642.15 Rpn2 2 Metabolic pathways; N-Glycan biosynthesis; Protein processing in endoplasmic reticulum 0 High P04117 "Fatty acid-binding protein, adipocyte OS=Mus musculus OX=10090 GN=Fabp4 PE=1 SV=3" 0 4.234 16 2 3 2 132 14.6 8.4 1 1 1 1 1 1 1264784.438 2008142.063 1878155.5 1803818.063 2 2 2 2 cell differentiation;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;nucleus transporter activity Pf00061 11770 ENSMUSG00000062515.3 Fabp4 3 Triglyceride catabolism; Mus musculus biological processes; Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes PPAR signaling pathway; Regulation of lipolysis in adipocytes 0 High Q60847 Collagen alpha-1(XII) chain OS=Mus musculus OX=10090 GN=Col12a1 PE=2 SV=3 0 4.768 1 3 3 3 3120 340 5.64 3 3 1459569.75 864976.5938 1220418.688 1923781.625 3 3 3 3 cell differentiation extracellular protein binding "Pf00041, Pf00092, Pf13519" 12816 Col12a1 9 Collagen chain trimerization; Collagen degradation; Assembly of collagen fibrils and other multimeric structures Protein digestion and absorption 0 High P62281 40S ribosomal protein S11 OS=Mus musculus OX=10090 GN=Rps11 PE=1 SV=3 0 4.649 22 3 3 3 158 18.4 10.3 3 3 929226.4219 2563037.563 1395841.625 3743780.125 3 3 3 3 cell differentiation;metabolic process cytoplasm;membrane;ribosome RNA binding;structural molecule activity Pf00366 27207 ENSMUSG00000003429.11 Rps11 7 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High O70325 Phospholipid hydroperoxide glutathione peroxidase OS=Mus musculus OX=10090 GN=Gpx4 PE=1 SV=4 0 2.716 10 2 3 2 197 22.2 8.46 1 1 1 1 1 1 513539.2969 658964.3281 480053.4531 975088.2813 2 2 2 2 cell organization and biogenesis;development;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus antioxidant activity;catalytic activity;protein binding Pf00255 625249 ENSMUSG00000075706.10 Gpx4 10 Synthesis of 12-eicosatetraenoic acid derivatives; Synthesis of 15-eicosatetraenoic acid derivatives Glutathione metabolism 0 High P14131 40S ribosomal protein S16 OS=Mus musculus OX=10090 GN=Rps16 PE=1 SV=4 0 5.304 19 3 3 3 146 16.4 10.21 3 3 198666.1328 574503.7031 398794.7031 1070820.344 2 2 2 2 metabolic process membrane;ribosome RNA binding;structural molecule activity Pf00380 100039355; 20055 ENSMUSG00000037563.15 Rps16-ps2; Rps16 5; 7 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High Q9CQR4 Acyl-coenzyme A thioesterase 13 OS=Mus musculus OX=10090 GN=Acot13 PE=1 SV=1 0 2.399 7 1 3 1 140 15.2 8.82 1 1 1 1 1 1 1287365.625 1603834.625 1944396.625 1965666.125 1 1 1 1 cell organization and biogenesis cytoplasm;cytoskeleton;cytosol;mitochondrion;nucleus catalytic activity Pf03061 66834 ENSMUSG00000006717.6 Acot13 13 Mitochondrial Fatty Acid Beta-Oxidation 0 High H3BLI5 Coiled-coil domain-containing protein 137 (Fragment) OS=Mus musculus OX=10090 GN=Ccdc137 PE=1 SV=1 0.01 1.243 4 1 3 1 241 27.1 10.21 1 1 1 2 16160371.63 11830189.59 14791998.97 13485388 1 1 1 1 ENSMUSG00000049957.14 11 0 High P43274 Histone H1.4 OS=Mus musculus OX=10090 GN=H1-4 PE=1 SV=2 0.013 1.495 5 1 3 1 219 22 11.11 1 1 1 2 717807.9375 469930.9063 254525.2813 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process chromosome;nucleus DNA binding;metal ion binding;nucleotide binding;protein binding;RNA binding Pf00538 50709 ENSMUSG00000051627.2 Hist1h1e 13 0 High P01901 "H-2 class I histocompatibility antigen, K-B alpha chain OS=Mus musculus OX=10090 GN=H2-K1 PE=1 SV=1" 0 3.006 6 2 3 2 369 41.3 6.39 2 3 10163.77539 769992.3125 1 2 defense response;regulation of biological process;response to stimulus cell surface;endoplasmic reticulum;Golgi;membrane protein binding;RNA binding "Pf00129, Pf06623, Pf07654" 14972 ENSMUSG00000061232.15 H2-K1 17 Endocytosis; Herpes simplex infection; Allograft rejection; Epstein-Barr virus infection; Cell adhesion molecules (CAMs); HTLV-I infection; Phagosome; Graft-versus-host disease; Viral myocarditis; Antigen processing and presentation; Type I diabetes mellitus; Natural killer cell mediated cytotoxicity; Autoimmune thyroid disease; Viral carcinogenesis 0 Medium P97351 40S ribosomal protein S3a OS=Mus musculus OX=10090 GN=Rps3a PE=1 SV=3 0.016 1.076 3 1 3 1 264 29.9 9.73 1 1 1 2 103626.0781 477618.1563 243254.6406 298619.8125 1 1 1 1 cell differentiation;metabolic process;regulation of biological process cytoplasm;cytosol;endoplasmic reticulum;nucleus;ribosome protein binding;RNA binding;structural molecule activity Pf01015 20091 ENSMUSG00000028081.6 Rps3a; Rps3a1 3 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High E9QQ30 Eukaryotic translation initiation factor 2-alpha kinase 3 OS=Mus musculus OX=10090 GN=Eif2ak3 PE=1 SV=1 0 4.234 3 3 3 3 1114 124.6 5.25 1 2 1 2 10562.125 1130668.922 922852.3125 1 3 3 cell communication;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;membrane catalytic activity;nucleotide binding;protein binding "Pf00069, Pf07714, Pf13360, Pf14531" 13666 ENSMUSG00000031668.14 Eif2ak3 6 PERK regulates gene expression 0 High A0A1L1STE6 "Isocitrate dehydrogenase [NAD] subunit, mitochondrial OS=Mus musculus OX=10090 GN=Idh3a PE=1 SV=1" 0 2.883 5 2 3 2 384 41.5 6.93 1 2 1 2 1376698.844 941139.8438 1069128.797 1802641.375 2 2 2 2 metabolic process mitochondrion catalytic activity;metal ion binding;nucleotide binding Pf00180 ENSMUSG00000032279.11 9 0 High Q62087 Serum paraoxonase/lactonase 3 OS=Mus musculus OX=10090 GN=Pon3 PE=1 SV=2 0 2.927 3 1 3 1 354 39.3 5.74 1 3 986089.125 1 metabolic process;regulation of biological process;response to stimulus extracellular catalytic activity;metal ion binding;protein binding "Pf01731, Pf03088" 269823 ENSMUSG00000029759.9 Pon3 6 Synthesis of 5-eicosatetraenoic acids Metabolic pathways 0 High Q8R0Y8 Mitochondrial coenzyme A transporter SLC25A42 OS=Mus musculus OX=10090 GN=Slc25a42 PE=1 SV=1 0 4.098 12 3 3 3 318 35.2 10.05 3 3 83886.90625 100861.4102 1949921.031 2 2 3 transport membrane;mitochondrion;nucleus catalytic activity;transporter activity Pf00153 73095 ENSMUSG00000002346.16 Slc25a42 8 0 High A0A2R8VHP3 Predicted pseudogene 5478 OS=Mus musculus OX=10090 GN=Gm5478 PE=1 SV=1 0 3.251 2 2 3 2 535 57.9 6.2 2 3 3369598.75 4904369.625 3568422 7050488.25 2 2 2 2 0 High P47915 60S ribosomal protein L29 OS=Mus musculus OX=10090 GN=Rpl29 PE=1 SV=2 0 3.008 12 2 3 2 160 17.6 11.84 1 1 1 1 1 1 534192.25 1427517.156 1055108.5 1289929.375 1 2 2 2 cell proliferation;metabolic process ribosome structural molecule activity Pf01779 19944; 666642 ENSMUSG00000048758.14 Rpl29; Gm8210 9; 1 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q7TPH6 E3 ubiquitin-protein ligase MYCBP2 OS=Mus musculus OX=10090 GN=Mycbp2 PE=1 SV=3 0 3.145 0 2 3 2 4749 520.9 7.09 1 2 1 2 800702.9688 753123.2813 210053.9688 2 2 1 0 High P99027 60S acidic ribosomal protein P2 OS=Mus musculus OX=10090 GN=Rplp2 PE=1 SV=3 0 3.693 17 2 3 2 115 11.6 4.54 1 1 1 1 1 1 560163.3906 1243028.719 797588.125 867782.8125 2 2 2 2 metabolic process membrane;ribosome structural molecule activity Pf00428 67186 ENSMUSG00000025508.13 Rplp2 7 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High P12382 "ATP-dependent 6-phosphofructokinase, liver type OS=Mus musculus OX=10090 GN=Pfkl PE=1 SV=4" 0 5.25 5 3 3 3 780 85.3 7.17 3 3 65220.25781 34159.73438 34859.30469 1162985.563 1 1 1 3 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane catalytic activity;metal ion binding;nucleotide binding;protein binding Pf00365 18641 ENSMUSG00000020277.10 Pfkl 10 Neutrophil degranulation; Glycolysis RNA degradation; Metabolic pathways; Biosynthesis of amino acids; Glycolysis / Gluconeogenesis; Pentose phosphate pathway; HIF-1 signaling pathway; AMPK signaling pathway; Carbon metabolism; Fructose and mannose metabolism; Galactose metabolism; Central carbon metabolism in cancer; Glucagon signaling pathway 0 High Q8K3B1 F-box/SPRY domain-containing protein 1 OS=Mus musculus OX=10090 GN=Fbxo45 PE=1 SV=2 0 4.022 12 3 3 3 286 30.6 7.85 1 2 1 2 22829.74805 673972.1719 778368.6406 532159.4219 1 3 3 3 cell organization and biogenesis;cellular component movement;development;metabolic process;response to stimulus membrane protein binding "Pf00622, Pf00646, Pf12937" 268882 ENSMUSG00000035764.5 Fbxo45 16 0 High Q9Z2Z6 Mitochondrial carnitine/acylcarnitine carrier protein OS=Mus musculus OX=10090 GN=Slc25a20 PE=1 SV=1 0 5.641 10 3 3 3 301 33 9.11 3 3 307493.0469 303213.1719 408592.4688 1425546.563 3 3 3 3 Met-loss+Acetyl [N-Term] transport cytosol;membrane;mitochondrion transporter activity Pf00153 57279 ENSMUSG00000032602.6 Slc25a20 9 Import of palmitoyl-CoA into the mitochondrial matrix 0 High Q9Z1E4 "Glycogen [starch] synthase, muscle OS=Mus musculus OX=10090 GN=Gys1 PE=1 SV=2" 0 3.816 6 3 3 3 738 83.9 6.11 1 2 1 2 955952.5156 1950157.906 1669911.813 1373167.938 3 3 3 3 metabolic process cytoplasm;membrane catalytic activity;protein binding "Pf00534, Pf05693, Pf13579" 14936 ENSMUSG00000003865.16 Gys1 7 Glycogen synthesis Insulin signaling pathway; Metabolic pathways; Insulin resistance; Starch and sucrose metabolism; PI3K-Akt signaling pathway; AMPK signaling pathway; Glucagon signaling pathway 0 High Q924L1 LETM1 domain-containing protein 1 OS=Mus musculus OX=10090 GN=Letmd1 PE=1 SV=1 0 5.195 8 3 3 3 360 41.7 10.54 3 3 456212.1563 858447.6094 705052.1875 1392697.125 2 3 3 3 cellular homeostasis membrane;mitochondrion Pf07766 68614 ENSMUSG00000037353.8 Letmd1 15 0 High J3QNW9 Kinesin-like protein KIF7 OS=Mus musculus OX=10090 GN=Kif7 PE=1 SV=1 0 3.21 2 1 3 1 1348 151.6 6.57 1 1 2 1 623390912 581552288 449547040 83579192 2 2 2 1 cellular component movement;regulation of biological process cytoplasm;cytoskeleton catalytic activity;motor activity;nucleotide binding;protein binding "Pf00225, Pf09726" 16576 ENSMUSG00000050382.14 Kif7 7 Hedgehog 'on' state; Hedgehog 'off' state Hedgehog signaling pathway 0 High Q01149 Collagen alpha-2(I) chain OS=Mus musculus OX=10090 GN=Col1a2 PE=1 SV=2 0 3.533 2 3 3 3 1372 129.5 9.19 1 2 1 2 6696703.75 1200577.156 1892409 1546457.969 3 3 3 3 cell organization and biogenesis;regulation of biological process;response to stimulus endoplasmic reticulum;extracellular metal ion binding;protein binding;structural molecule activity "Pf01391, Pf01410" 12843 ENSMUSG00000029661.16 Col1a2 6 Anchoring fibril formation; ECM proteoglycans; Cell surface interactions at the vascular wall; Platelet Aggregation (Plug Formation); Integrin cell surface interactions; Collagen degradation; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; Crosslinking of collagen fibrils; Collagen chain trimerization; GP1b-IX-V activation signalling; Platelet Adhesion to exposed collagen; MET activates PTK2 signaling; GPVI-mediated activation cascade; Non-integrin membrane-ECM interactions AGE-RAGE signaling pathway in diabetic complications; Focal adhesion; Protein digestion and absorption; Platelet activation; Proteoglycans in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway; Amoebiasis 0 High A2AJW4 "Protein phosphatase 1, regulatory subunit 3D OS=Mus musculus OX=10090 GN=Ppp1r3d PE=1 SV=1" 0 5.424 13 3 3 3 279 30.5 8.25 1 2 1 2 354511.4375 672098.6875 415936.7969 609992.3125 2 2 2 2 metabolic process;regulation of biological process catalytic activity;protein binding Pf03370 228966 ENSMUSG00000049999.4 Ppp1r3d 2 Insulin signaling pathway; Insulin resistance 0 High Q9DB20 "ATP synthase subunit O, mitochondrial OS=Mus musculus OX=10090 GN=Atp5po PE=1 SV=1" 0 5.649 15 3 3 3 213 23.3 9.99 3 3 301519.375 33275.19531 97395.74219 1710740.125 1 1 2 3 metabolic process;transport membrane;mitochondrion;nucleus catalytic activity;protein binding;transporter activity Pf00213 28080; 102641678 ENSMUSG00000022956.10 Atp5o; LOC100047429; LOC102641678 16; 3 Cristae formation; Formation of ATP by chemiosmotic coupling Metabolic pathways; Huntington's disease; Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High P68510 14-3-3 protein eta OS=Mus musculus OX=10090 GN=Ywhah PE=1 SV=2 0 2.907 7 2 3 2 246 28.2 4.89 1 1 1 1 1 1 191476.0781 761473.9219 500573.1875 807618.4688 1 2 1 2 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;membrane protein binding Pf00244 22629 ENSMUSG00000018965.11 Ywhah 5 Translocation of GLUT4 to the plasma membrane; Activation of BAD and translocation to mitochondria ; RHO GTPases activate PKNs; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex Epstein-Barr virus infection; Hippo signaling pathway; Oocyte meiosis; Cell cycle; PI3K-Akt signaling pathway; Viral carcinogenesis 0 High P62911 60S ribosomal protein L32 OS=Mus musculus OX=10090 GN=Rpl32 PE=1 SV=2 0 2.072 13 2 2 2 135 15.9 11.33 1 1 1 1 955256.8438 1947231.688 1100970.125 554522.3125 2 2 1 1 Met-loss [N-Term] metabolic process;response to stimulus membrane;ribosome RNA binding;structural molecule activity Pf01655 19951; 652989 ENSMUSG00000057841.5 Rpl32; Rpl32p 6; X L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High A0A0B4J1J7 Immunoglobulin heavy variable 1-82 OS=Mus musculus OX=10090 GN=Ighv1-82 PE=1 SV=1 0 2.297 27 2 2 2 98 10.6 9.29 2 2 1361093.219 1664217.25 657569.8281 1019730.656 2 2 2 2 Pf07686 16061 ENSMUSG00000095127.2 Igh-VJ558 12 0 High P47963 60S ribosomal protein L13 OS=Mus musculus OX=10090 GN=Rpl13 PE=1 SV=3 0 3.339 11 2 2 2 211 24.3 11.55 2 2 1090096.375 1490477.563 1038183.344 1126088.094 2 2 2 2 metabolic process membrane;nucleus;ribosome RNA binding;structural molecule activity Pf01294 270106 ENSMUSG00000000740.12 Rpl13 8 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High E9PUV4 S-phase kinase-associated protein 1A (Fragment) OS=Mus musculus OX=10090 GN=Skp1a PE=1 SV=1 0.012 1.354 8 1 2 1 96 10.6 4.7 1 1 1 1 1070950.375 832533.6875 1045367.125 1 1 1 metabolic process "Pf01466, Pf03931" ENSMUSG00000036309.14 11 0 High Q6P6J9 Thioredoxin domain-containing protein 15 OS=Mus musculus OX=10090 GN=Txndc15 PE=1 SV=1 0 2.665 10 2 2 2 344 38.1 4.77 2 2 412034.4375 1 cellular homeostasis;regulation of biological process membrane Pf00085 69672 ENSMUSG00000021497.9 Txndc15 13 0 High P24549 Retinal dehydrogenase 1 OS=Mus musculus OX=10090 GN=Aldh1a1 PE=1 SV=5 0 2.471 2 1 2 1 501 54.4 7.8 1 1 1 1 18741.50391 3031989 4147897 4322106 1 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;nucleus catalytic activity;nucleotide binding;protein binding "Pf00171, Pf05893, Pf07368" 11668 ENSMUSG00000053279.6 Aldh1a1 19 RA biosynthesis pathway; Ethanol oxidation; Fructose catabolism Retinol metabolism; Metabolic pathways 0 High Q9QZN4 F-box only protein 6 OS=Mus musculus OX=10090 GN=Fbxo6 PE=1 SV=1 0 2.454 7 2 2 2 295 34.5 8.18 2 2 473823.4063 366823.1094 933501.5 2 2 2 metabolic process;response to stimulus cytoplasm catalytic activity;protein binding "Pf00646, Pf04300, Pf12937" 50762 ENSMUSG00000055401.14 Fbxo6 4 Neddylation; Antigen processing: Ubiquitination & Proteasome degradation Protein processing in endoplasmic reticulum 0 High E9PZA4 Patatin-like phospholipase domain-containing protein 2 (Fragment) OS=Mus musculus OX=10090 GN=Pnpla2 PE=1 SV=1 0 3.164 7 2 2 2 305 33.5 7.15 2 2 273559 1 cell organization and biogenesis;metabolic process;regulation of biological process cytosol catalytic activity ENSMUSG00000025509.15 7 0 High P59913 Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 OS=Mus musculus OX=10090 GN=Pcmtd1 PE=1 SV=1 0 2.015 2 1 2 1 357 40.7 5.66 1 1 1 1 1685937.125 1649658 1330152.875 1221691.25 1 1 1 1 metabolic process cytoplasm;membrane catalytic activity "Pf01135, Pf12847, Pf13847" 319263 ENSMUSG00000051285.17 Pcmtd1 1 0 High B1AWT7 Ubiquitin-conjugating enzyme E2 J1 (Fragment) OS=Mus musculus OX=10090 GN=Ube2j1 PE=1 SV=1 0 4.627 13 2 2 2 157 16.8 5.97 2 2 825989.5313 2 metabolic process;regulation of biological process cytoplasm;endoplasmic reticulum;membrane catalytic activity;nucleotide binding;protein binding Pf00179 56228 ENSMUSG00000028277.13 Ube2j1 4 0 High P62264 40S ribosomal protein S14 OS=Mus musculus OX=10090 GN=Rps14 PE=1 SV=3 0 3.243 16 2 2 2 151 16.3 10.05 2 2 120854.1172 580306.5 916085.0313 1790634.25 1 2 2 2 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process membrane;mitochondrion;ribosome RNA binding;structural molecule activity;translation regulator activity Pf00411 20044 ENSMUSG00000024608.10 Rps14 18 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High Q9D9N8 Protease-associated domain-containing protein 1 OS=Mus musculus OX=10090 GN=Pradc1 PE=1 SV=1 0 2.435 9 2 2 2 188 21.1 5.72 2 2 2124243.938 2 extracellular Pf02225 73327 ENSMUSG00000030008.9 Pradc1 6 0 High Q8K297 Procollagen galactosyltransferase 1 OS=Mus musculus OX=10090 GN=Colgalt1 PE=1 SV=2 0 3.015 3 2 2 2 617 71 7.28 2 2 706794.125 2 endoplasmic reticulum;membrane;organelle lumen catalytic activity Pf01755 234407 ENSMUSG00000034807.9 Glt25d1; Colgalt1 8 Collagen biosynthesis and modifying enzymes Lysine degradation; Other types of O-glycan biosynthesis 0 High D3Z7R9 Cell cycle progression protein 1 OS=Mus musculus OX=10090 GN=Ccpg1 PE=1 SV=1 0 2.725 2 2 2 2 778 89.1 6.06 2 2 720330.4063 2 regulation of biological process membrane protein binding 72278 ENSMUSG00000034563.16 Ccpg1 9 0 High F6RYG0 All-trans retinoic acid-induced differentiation factor (Fragment) OS=Mus musculus OX=10090 GN=Atraid PE=1 SV=1 0 2.646 5 1 2 1 183 19.7 5.1 1 2 3511812.25 1 ENSMUSG00000013622.15 5 0 High P62267 40S ribosomal protein S23 OS=Mus musculus OX=10090 GN=Rps23 PE=1 SV=3 0.013 1.442 6 1 2 1 143 15.8 10.49 1 1 1 1 673243.25 1 cell organization and biogenesis;metabolic process membrane;ribosome RNA binding;structural molecule activity Pf00164 66475 ENSMUSG00000049517.7 Rps23 13 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High P11087 Collagen alpha-1(I) chain OS=Mus musculus OX=10090 GN=Col1a1 PE=1 SV=4 0 2.547 1 2 2 2 1453 137.9 5.85 1 1 1 1 1410631.5 291630.1563 470412.1563 386513.5313 1 1 1 1 cell communication;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;extracellular;Golgi metal ion binding;protein binding;structural molecule activity "Pf00093, Pf01391, Pf01410" 12842 ENSMUSG00000001506.10 Col1a1 11 Anchoring fibril formation; ECM proteoglycans; Cell surface interactions at the vascular wall; Platelet Aggregation (Plug Formation); Integrin cell surface interactions; Collagen degradation; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; Crosslinking of collagen fibrils; Collagen chain trimerization; GP1b-IX-V activation signalling; Platelet Adhesion to exposed collagen; MET activates PTK2 signaling; GPVI-mediated activation cascade; Non-integrin membrane-ECM interactions AGE-RAGE signaling pathway in diabetic complications; Focal adhesion; Protein digestion and absorption; Platelet activation; Proteoglycans in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway; Amoebiasis 0 High P50172 Corticosteroid 11-beta-dehydrogenase isozyme 1 OS=Mus musculus OX=10090 GN=Hsd11b1 PE=1 SV=3 0 3.165 6 2 2 2 292 32.3 8.46 2 2 9022.741211 501713.6875 1 1 metabolic process;regulation of biological process cytoplasm;endoplasmic reticulum;membrane catalytic activity;nucleotide binding "Pf00106, Pf08643, Pf08659, Pf13460, Pf13561" 15483 ENSMUSG00000016194.14 Hsd11b1 1 Glucocorticoid biosynthesis Steroid hormone biosynthesis; Metabolic pathways; Chemical carcinogenesis; Metabolism of xenobiotics by cytochrome P450 0 Medium H7BX95 Serine/arginine-rich-splicing factor 1 OS=Mus musculus OX=10090 GN=Srsf1 PE=1 SV=1 0.016 1.074 4 1 2 1 253 28.3 10.08 1 1 1 1 223844.8281 140560.9531 228073.8281 162253.8594 1 1 1 1 metabolic process nucleus protein binding;RNA binding "Pf00076, Pf13893, Pf14259" ENSMUSG00000018379.17; ENSMUSG00000098301.6 11; CHR_MG3829_PATCH 0 High G3UYC6 Synaptotagmin-like protein 4 (Fragment) OS=Mus musculus OX=10090 GN=Sytl4 PE=1 SV=8 0.011 1.256 5 1 2 1 185 21.6 9.07 1 2 74106624 94488024 58714184 46240728 1 1 1 1 regulation of biological process;transport protein binding Pf02318 ENSMUSG00000031255.14 X 0 High Q922Q8 Leucine-rich repeat-containing protein 59 OS=Mus musculus OX=10090 GN=Lrrc59 PE=1 SV=1 0.013 1.481 3 1 2 1 307 34.9 9.52 1 1 1 1 109665.3281 438786.0313 99703.32031 191620 1 1 1 1 endoplasmic reticulum;membrane;nucleus protein binding;RNA binding "Pf12799, Pf13855" 98238 ENSMUSG00000020869.8 Lrrc59 11 0 High P45952 "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Acadm PE=1 SV=1" 0.007 1.669 2 1 2 1 421 46.5 8.37 1 2 344776.625 274860.4375 385640.0938 668269.5 1 1 1 1 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion;nucleus;organelle lumen catalytic activity;nucleotide binding;protein binding "Pf00441, Pf02770, Pf02771, Pf08028" 11364 ENSMUSG00000062908.12 Acadm 3 mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA "PPAR signaling pathway; Fatty acid metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Fatty acid degradation; beta-Alanine metabolism; Propanoate metabolism; Carbon metabolism" 0 High Q6AXE3 ATP-binding cassette sub-family A member 3 OS=Mus musculus OX=10090 GN=Abca3 PE=1 SV=1 0 1.739 1 1 2 1 1449 163.4 7.83 1 2 28844962 23487758 19169619.5 21545425 1 1 1 1 transport membrane catalytic activity;nucleotide binding;transporter activity "Pf00005, Pf03193, Pf12698, Pf13304, Pf13476" 27410 ENSMUSG00000024130.15 Abca3 17 ABC transporters 0 High Q61646 Haptoglobin OS=Mus musculus OX=10090 GN=Hp PE=1 SV=1 0 2.771 6 2 2 2 347 38.7 6.29 2 2 431266.1875 1112308.406 2014890.813 2 2 2 defense response;metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;extracellular;Golgi antioxidant activity;catalytic activity;protein binding "Pf00084, Pf00089" 15439 ENSMUSG00000031722.10 Hp 8 Neutrophil degranulation; Scavenging of heme from plasma 0 High P62242 40S ribosomal protein S8 OS=Mus musculus OX=10090 GN=Rps8 PE=1 SV=2 0 2.27 6 1 2 1 208 24.2 10.32 1 1 1 1 290884.375 529196.5 296150.3125 440068.0938 1 1 1 1 metabolic process cytoplasm;cytosol;endoplasmic reticulum;membrane;nucleus;ribosome RNA binding;structural molecule activity Pf01201 20116; 100040298 ENSMUSG00000047675.15 Rps8; Gm15501 4; 7 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High Q6ZWZ4 60S ribosomal protein L36 OS=Mus musculus OX=10090 GN=Rpl36 PE=1 SV=1 0 1.816 9 1 2 1 105 12.2 11.59 1 1 1 1 544168 1044329.625 905514.4375 527804.5625 1 1 1 1 metabolic process ribosome RNA binding;structural molecule activity Pf01158 54217 ENSMUSG00000057863.5 Rpl36 17 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High P67778 Prohibitin OS=Mus musculus OX=10090 GN=Phb PE=1 SV=1 0 4.831 9 2 2 2 272 29.8 5.76 2 2 97589.78125 94127.57031 115006.2539 1087152.469 1 1 2 2 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;endosome;membrane;mitochondrion;nucleus DNA binding;protein binding Pf01145 18673 ENSMUSG00000038845.11 Phb 11 RAF activation; Interleukin-20 family signaling; Processing of SMDT1 0 High A0A087WS16 "Collagen, type VI, alpha 3 OS=Mus musculus OX=10090 GN=Col6a3 PE=1 SV=1" 0.011 1.249 0 1 2 1 2677 288.5 8.53 1 1 1 1 382281.1875 262107.2344 248350.4688 1 1 1 regulation of biological process extracellular;membrane enzyme regulator activity;protein binding "Pf00014, Pf00041, Pf00092, Pf01391, Pf13519, Pf13768" ENSMUSG00000048126.16 1 ECM proteoglycans; Collagen chain trimerization; Integrin cell surface interactions; NCAM1 interactions; Collagen degradation; Signaling by PDGF; Assembly of collagen fibrils and other multimeric structures 0 High P62317 Small nuclear ribonucleoprotein Sm D2 OS=Mus musculus OX=10090 GN=Snrpd2 PE=1 SV=1 0.012 1.367 8 1 2 1 118 13.5 9.91 1 1 1 1 282898.375 694998.1875 449671.1875 183774.4063 1 1 1 1 cell organization and biogenesis;metabolic process cytoplasm;cytosol;nucleus;spliceosomal complex RNA binding Pf01423 107686 ENSMUSG00000040824.3 Snrpd2 7 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; snRNP Assembly Spliceosome 0 High Q63918 Caveolae-associated protein 2 OS=Mus musculus OX=10090 GN=Cavin2 PE=1 SV=3 0 4.06 6 2 2 2 418 46.7 5.21 2 2 549066.9063 2228950.375 445645.7344 397435.25 2 2 2 2 cell organization and biogenesis;regulation of biological process cytoplasm;cytosol;membrane protein binding Pf15237 20324 ENSMUSG00000045954.7 Sdpr; Cavin2 1 0 High P62274 40S ribosomal protein S29 OS=Mus musculus OX=10090 GN=Rps29 PE=1 SV=2 0 3.033 34 2 2 2 56 6.7 10.13 2 2 246810.0469 376737.3438 1 1 Met-loss [N-Term] metabolic process;regulation of biological process ribosome metal ion binding;structural molecule activity Pf00253 20090 ENSMUSG00000034892.8 Rps29 12 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High Q9D6F9 Tubulin beta-4A chain OS=Mus musculus OX=10090 GN=Tubb4a PE=1 SV=3 0 4.013 5 2 2 2 444 49.6 4.88 2 2 101051.6797 96781.51563 263307.9922 1073899.031 1 1 2 2 cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton;nucleus catalytic activity;metal ion binding;nucleotide binding;structural molecule activity "Pf00091, Pf03953, Pf10644" 22153 ENSMUSG00000062591.5 Tubb4a 17 Anchoring of the basal body to the plasma membrane; Intraflagellar transport; Hedgehog 'on' state; AURKA Activation by TPX2; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Hedgehog 'off' state; Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes Phagosome; Gap junction 0 High Q9JJY4 Probable ATP-dependent RNA helicase DDX20 OS=Mus musculus OX=10090 GN=Ddx20 PE=1 SV=2 0 2.466 3 2 2 2 825 91.7 6.74 1 1 1 1 625195.1094 493595.9063 441518.625 2 2 2 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;cytosol;membrane;nucleus catalytic activity;DNA binding;nucleotide binding;protein binding "Pf00270, Pf00271" 53975 ENSMUSG00000027905.15 Ddx20 3 snRNP Assembly RNA transport 0 High K4DI77 WD repeat-containing protein 81 (Fragment) OS=Mus musculus OX=10090 GN=Wdr81 PE=1 SV=1 0 2.684 1 2 2 2 1934 211.8 5.77 1 1 1 1 6547.774902 580871.9375 475221.7656 182629.2734 1 2 2 2 cell organization and biogenesis mitochondrion protein binding "Pf00400, Pf02138" ENSMUSG00000045374.18 11 0 High A2ADH1 Magnesium transporter protein 1 OS=Mus musculus OX=10090 GN=Magt1 PE=1 SV=1 0 3.598 5 2 2 2 368 41.6 10.05 2 2 29645.20703 13642.58008 1993618.5 1 1 2 metabolic process;transport endoplasmic reticulum;membrane catalytic activity;transporter activity Pf04756 67075 ENSMUSG00000031232.16 Magt1 X Neutrophil degranulation; Miscellaneous transport and binding events 0 High Q8CG16 Complement C1r-A subcomponent OS=Mus musculus OX=10090 GN=C1ra PE=1 SV=1 0 2.552 3 2 2 2 707 80 5.66 2 2 453078.7188 142694.9375 643467.2031 1 1 2 defense response;metabolic process;regulation of biological process;response to stimulus catalytic activity;metal ion binding "Pf00084, Pf00089, Pf00431, Pf07645, Pf12662, Pf14670" 50909 ENSMUSG00000055172.10 C1ra 6 Regulation of Complement cascade; Classical antibody-mediated complement activation Staphylococcus aureus infection; Phagosome; Complement and coagulation cascades; Pertussis; Systemic lupus erythematosus 0 High E9Q0B5 Fc fragment of IgG-binding protein OS=Mus musculus OX=10090 GN=Fcgbp PE=1 SV=1 0 1.796 0 1 2 1 2583 275 5.03 1 1 1 1 11000842 9884583 4743629.5 13174266 1 1 1 1 protein binding "Pf00094, Pf01826, Pf08742, Pf12714" ENSMUSG00000047730.17 7 0 High B1ARA5 60S ribosomal protein L26 OS=Mus musculus OX=10090 GN=Rpl26 PE=1 SV=1 0.01 1.187 6 1 2 1 143 17 10.55 1 1 1 1 309696.4688 445635.8438 188445.8906 1 1 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;ribosome protein binding;RNA binding;structural molecule activity 19941 ENSMUSG00000060938.14 Rpl26 11 0 High P00405 Cytochrome c oxidase subunit 2 OS=Mus musculus OX=10090 GN=Mtco2 PE=1 SV=1 0.013 1.453 3 1 2 1 227 26 4.73 1 1 1 1 159140.7969 246104.875 269722.5 943370.3125 1 1 1 1 metabolic process;response to stimulus;transport membrane;mitochondrion catalytic activity;metal ion binding;transporter activity "Pf00116, Pf02790" 17709; 3338897 ENSMUSG00000064354.1 COX2 MT Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 High Q921R2 40S ribosomal protein S13 OS=Mus musculus OX=10090 GN=Rps13 PE=1 SV=1 0 2.787 14 2 2 2 140 16.1 10.71 2 2 126356.25 2027775.5 601073.625 2028547.125 1 2 1 2 metabolic process;regulation of biological process membrane;nucleus;ribosome RNA binding;structural molecule activity "Pf00312, Pf08069" 68052 ENSMUSG00000090862.3 Rps13 7 0 High A0A087WQ01 Inactive tyrosine-protein kinase PEAK1 OS=Mus musculus OX=10090 GN=Peak1 PE=1 SV=1 0 2.064 2 1 2 1 705 78.8 5.92 1 1 1 1 459568.1563 463784.75 404372.25 1 1 1 metabolic process catalytic activity;nucleotide binding Pf00069 ENSMUSG00000074305.9 9 0 High A0A0G2JGY8 60S ribosomal protein L34 (Fragment) OS=Mus musculus OX=10090 GN=Rpl34 PE=1 SV=4 0.013 1.564 15 1 2 1 59 6.7 11.66 1 1 1 1 504364.3438 707819.6875 367845.5313 462872 1 1 1 1 metabolic process mitochondrion;ribosome structural molecule activity Pf01199 ENSMUSG00000062006.12 3 0 High A0A0U1RNL7 Protein-serine/threonine kinase OS=Mus musculus OX=10090 GN=Bckdk PE=1 SV=1 0 3.325 10 2 2 2 335 38 9.42 1 1 1 1 448425.6094 782010.2188 301482.3125 762501.1719 2 2 2 2 metabolic process mitochondrion catalytic activity Pf10436 ENSMUSG00000030802.14 7 0 High D3Z0B1 Tyrosine 3-monooxygenase (Fragment) OS=Mus musculus OX=10090 GN=Th PE=1 SV=1 0.01 1.237 5 1 2 1 171 18.9 6.54 1 1 1 1 688152.1875 1 cell communication;metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus catalytic activity;metal ion binding Pf00351 ENSMUSG00000000214.11 7 0 High P05214 Tubulin alpha-3 chain OS=Mus musculus OX=10090 GN=Tuba3a PE=1 SV=1 0 4.467 4 2 2 2 450 49.9 5.1 2 2 133243.7813 269396.7266 201967.5313 1068800.375 1 2 1 2 cell organization and biogenesis cytoplasm;cytoskeleton;nucleus catalytic activity;nucleotide binding;structural molecule activity "Pf00091, Pf03953" 22147; 22144 ENSMUSG00000067338.6; ENSMUSG00000067702.5 Tuba3b; Tuba3a 6 Intraflagellar transport; Hedgehog 'on' state; Hedgehog 'off' state Phagosome; Gap junction; Apoptosis 0 High E9Q6M6 Mitochondrial glutamate carrier 1 OS=Mus musculus OX=10090 GN=Slc25a22 PE=1 SV=1 0 2.73 6 1 2 1 229 24.6 8.6 1 2 64040.44922 81100.02344 115005.5547 889960.875 1 1 1 1 transport membrane;mitochondrion Pf00153 ENSMUSG00000019082.18 7 0 High E9Q8K5 Titin OS=Mus musculus OX=10090 GN=Ttn PE=1 SV=1 0.011 1.283 0 1 2 1 33467 3713.7 6.37 1 1 1 1 11734583 44184008 35225336 38103096 1 1 1 1 metabolic process catalytic activity;nucleotide binding;protein binding "Pf00041, Pf00047, Pf00069, Pf07679, Pf07686, Pf07714, Pf09042, Pf13895, Pf13927" ENSMUSG00000051747.14 2 0 High Q64523 Histone H2A type 2-C OS=Mus musculus OX=10090 GN=H2ac20 PE=1 SV=3 0 2.404 7 1 2 1 129 14 10.9 1 1 1 1 373218.1875 1894107.5 688283.625 1025186.438 1 1 1 1 regulation of biological process chromosome;nucleus DNA binding;protein binding "Pf00125, Pf00808" 319176 ENSMUSG00000068855.3 Hist2h2ac 3 RMTs methylate histone arginines; Meiotic Recombination; Mus musculus biological processes; Ub-specific processing proteases; NoRC negatively regulates rRNA expression; UCH proteinases; Metalloprotease DUBs; Meiotic Synapsis Alcoholism; Systemic lupus erythematosus 0 High Q8C0L0 Thioredoxin-related transmembrane protein 4 OS=Mus musculus OX=10090 GN=Tmx4 PE=1 SV=2 0 3.16 9 2 2 2 335 37.1 4.37 2 2 752839.5313 2 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport endoplasmic reticulum;membrane catalytic activity Pf00085 52837 ENSMUSG00000034723.11 Tmx4 2 0 High Q91VT4 Carbonyl reductase family member 4 OS=Mus musculus OX=10090 GN=Cbr4 PE=1 SV=2 0 3.362 9 2 2 2 236 25.4 9.69 2 2 187661.8672 191606.4531 263112.5625 1801157.125 2 2 2 2 cell organization and biogenesis;metabolic process mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf00106, Pf03435, Pf08659, Pf13561" 234309 ENSMUSG00000031641.14 Cbr4 8 Fatty acyl-CoA biosynthesis 0 High A0A0N4SVE0 Electron transfer flavoprotein subunit beta OS=Mus musculus OX=10090 GN=Etfbl PE=3 SV=1 0 3.654 9 2 2 2 221 24.1 6.1 2 2 451705.1406 577862.125 248363.2188 2412279 2 2 1 2 metabolic process Pf01012 ENSMUSG00000107482.2 7 Protein methylation; Respiratory electron transport 0 High Q99LB2 Dehydrogenase/reductase SDR family member 4 OS=Mus musculus OX=10090 GN=Dhrs4 PE=1 SV=3 0.013 1.542 4 1 2 1 279 29.9 9.38 1 1 1 1 539187 635440.75 754874.9063 220755.7344 1 1 1 1 cell organization and biogenesis;metabolic process membrane;mitochondrion;nucleus catalytic activity;protein binding "Pf00106, Pf08659, Pf13561" 28200 ENSMUSG00000022210.6 Dhrs4 14 RA biosynthesis pathway Retinol metabolism; Metabolic pathways; Peroxisome 0 High F7CJS8 40S ribosomal protein S9 (Fragment) OS=Mus musculus OX=10090 GN=Rps9 PE=1 SV=1 0 3.004 13 2 2 2 135 16.2 10.8 2 2 1173401.813 1960248.125 814467.125 1169804.625 2 2 1 2 metabolic process ribosome RNA binding;structural molecule activity "Pf00163, Pf01479" ENSMUSG00000006333.14 7 0 High Q2TPA8 Hydroxysteroid dehydrogenase-like protein 2 OS=Mus musculus OX=10090 GN=Hsdl2 PE=1 SV=1 0 2.384 3 1 2 1 490 54.2 6.74 1 2 120533.3359 207886.4688 161130.4531 497220.2813 1 1 1 1 metabolic process membrane;mitochondrion catalytic activity "Pf00106, Pf02036, Pf14864" 72479 ENSMUSG00000028383.17 Hsdl2 4 0 High D3Z041 Long-chain-fatty-acid--CoA ligase 1 OS=Mus musculus OX=10090 GN=Acsl1 PE=1 SV=1 0 2.93 3 2 2 2 699 78 7.47 2 2 207630.2344 245222.9219 171392.1875 2176867.063 1 1 1 2 metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion catalytic activity Pf00501 ENSMUSG00000018796.13 8 0 High Q8CG14 Complement C1s-A subcomponent OS=Mus musculus OX=10090 GN=C1sa PE=2 SV=2 0 3.063 3 2 2 2 688 76.8 5.08 2 2 744301.125 300762.0938 594153.7813 1531328.219 1 1 2 2 defense response;metabolic process;regulation of biological process;response to stimulus extracellular catalytic activity;metal ion binding;protein binding "Pf00084, Pf00089, Pf00431, Pf07645, Pf14670" 50908 C1s; C1s1 6 Staphylococcus aureus infection; Complement and coagulation cascades; Pertussis; Systemic lupus erythematosus 0 High Q8K3K7 1-acyl-sn-glycerol-3-phosphate acyltransferase beta OS=Mus musculus OX=10090 GN=Agpat2 PE=1 SV=1 0 1.72 4 1 1 1 278 31 8.88 1 1 711628.0625 1 metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;membrane catalytic activity Pf01553 67512 ENSMUSG00000026922.13 Agpat2 2 Neutrophil degranulation; Synthesis of PA Phospholipase D signaling pathway; Fat digestion and absorption; Metabolic pathways; Glycerophospholipid metabolism; Glycerolipid metabolism 0 High E0CXJ2 Seipin OS=Mus musculus OX=10090 GN=Bscl2 PE=1 SV=1 0.014 1.602 4 1 1 1 213 23.6 8.88 1 1 737635.9375 760684.4375 470869.9688 618227.6875 1 1 1 1 membrane Pf06775 ENSMUSG00000071657.12 19 0 Medium P70168 Importin subunit beta-1 OS=Mus musculus OX=10090 GN=Kpnb1 PE=1 SV=2 0.018 1.054 1 1 1 1 876 97.1 4.78 1 1 1717435.875 1479122.75 1730862.25 1436570.375 1 1 1 1 cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;membrane;nucleus protein binding;RNA binding;transporter activity "Pf02985, Pf03810, Pf13513" 16211 ENSMUSG00000001440.5 Kpnb1 11 Activation of DNA fragmentation factor; Neutrophil degranulation; Regulation of cholesterol biosynthesis by SREBP (SREBF) RNA transport 0 High P62751 60S ribosomal protein L23a OS=Mus musculus OX=10090 GN=Rpl23a PE=1 SV=1 0 3.183 8 1 1 1 156 17.7 10.45 1 1 305790.2813 947271.1875 315579.8438 725542.3125 1 1 1 1 cell organization and biogenesis;metabolic process nucleus;ribosome protein binding;RNA binding;structural molecule activity "Pf00276, Pf03939" 268449 ENSMUSG00000058546.8 Rpl23a 11 Ribosome 0 High A0A0A0MQM2 Phosphoinositide phospholipase C OS=Mus musculus OX=10090 GN=Plch1 PE=1 SV=1 0.01 1.181 1 1 1 1 1073 122.5 7.72 1 1 2771156.5 1 metabolic process;regulation of biological process;response to stimulus catalytic activity;metal ion binding;protein binding;signal transducer activity "Pf00036, Pf00168, Pf00387, Pf00388, Pf09279, Pf13499, Pf14788" ENSMUSG00000036834.16 3 0 High P05208 Chymotrypsin-like elastase family member 2A OS=Mus musculus OX=10090 GN=Cela2a PE=1 SV=1 0 2.442 3 1 1 1 271 28.9 8.62 1 1 1778003.75 764550.8125 129827.8516 1 1 1 metabolic process extracellular catalytic activity Pf00089 13706 ENSMUSG00000058579.5 Cela2a 4 Formation of the cornified envelope Pancreatic secretion; Protein digestion and absorption 0 Medium D3Z4R1 Probable ATP-dependent DNA helicase HFM1 OS=Mus musculus OX=10090 GN=Hfm1 PE=3 SV=2 0.017 1.12 0 1 1 1 1434 161.3 7.85 1 1 3887375.75 3100728.25 3319396.75 1631819 1 1 1 1 cell differentiation;metabolic process cytoplasm catalytic activity;DNA binding;nucleotide binding "Pf00270, Pf00271, Pf02889, Pf04851" 330149 ENSMUSG00000043410.16 Hfm1 5 0 High Q9DB15 "39S ribosomal protein L12, mitochondrial OS=Mus musculus OX=10090 GN=Mrpl12 PE=1 SV=2" 0.012 1.411 7 1 1 1 201 21.7 9.29 1 1 457778.9063 787480.125 755305.3125 1530100.625 1 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process mitochondrion;ribosome structural molecule activity Pf00542 56282 ENSMUSG00000039640.7 Mrpl12 11 Mitochondrial translation termination; Mitochondrial translation elongation Ribosome 0 Medium Q9QYC7 Vitamin K-dependent gamma-carboxylase OS=Mus musculus OX=10090 GN=Ggcx PE=1 SV=1 0.014 1.14 2 1 1 1 757 87.1 8.02 1 1 272586.4688 1 metabolic process endoplasmic reticulum;membrane catalytic activity Pf05090 56316 ENSMUSG00000053460.8; ENSMUSG00000103019.2 Ggcx 6; CHR_MG184_PATCH Gamma-carboxylation of protein precursors Ubiquinone and other terpenoid-quinone biosynthesis 0 High Q9JK53 Prolargin OS=Mus musculus OX=10090 GN=Prelp PE=1 SV=2 0 2.136 3 1 1 1 378 43.3 9.54 1 1 411502.6875 1 cell organization and biogenesis extracellular protein binding;structural molecule activity "Pf01462, Pf12799, Pf13855" 116847 ENSMUSG00000041577.5 Prelp 1 Keratan sulfate degradation; Keratan sulfate biosynthesis 0 High P10605 Cathepsin B OS=Mus musculus OX=10090 GN=Ctsb PE=1 SV=2 0.013 1.538 2 1 1 1 339 37.3 5.91 1 1 cell differentiation;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;extracellular;membrane;mitochondrion;vacuole catalytic activity;protein binding "Pf00112, Pf08127" 13030 ENSMUSG00000021939.7 Ctsb 14 Neutrophil degranulation; Collagen degradation; Trafficking and processing of endosomal TLR NOD-like receptor signaling pathway; Lysosome; Antigen processing and presentation; Renin secretion; Apoptosis 0 Medium P17182 Alpha-enolase OS=Mus musculus OX=10090 GN=Eno1 PE=1 SV=3 0.018 1.061 2 1 1 1 434 47.1 6.8 1 1 241759.5781 187557.6875 269872.8438 266652.0938 1 1 1 1 metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;cytosol;membrane;nucleus catalytic activity;DNA binding;metal ion binding;protein binding;RNA binding "Pf00113, Pf03952, Pf13378" 13806; 433182 ENSMUSG00000059040.4; ENSMUSG00000063524.13 Eno1; Gm5506; Eno1b 4; 18 Gluconeogenesis; Glycolysis RNA degradation; Metabolic pathways; Biosynthesis of amino acids; Glycolysis / Gluconeogenesis; HIF-1 signaling pathway; Carbon metabolism 0 Medium P18242 Cathepsin D OS=Mus musculus OX=10090 GN=Ctsd PE=1 SV=1 0.016 1.08 2 1 1 1 410 44.9 7.15 1 1 36111.11719 28220.77734 398672.0313 1 1 1 cell organization and biogenesis;metabolic process extracellular;membrane;mitochondrion;vacuole catalytic activity "Pf00026, Pf07966, Pf14541, Pf14543" 13033 ENSMUSG00000007891.16 Ctsd 7 MHC class II antigen presentation; Neutrophil degranulation; Collagen degradation Tuberculosis; Lysosome; Sphingolipid signaling pathway; Apoptosis 0 High A0A0R4J0L1 Beta-galactosidase OS=Mus musculus OX=10090 GN=Glb1l2 PE=1 SV=1 0.011 1.257 2 1 1 1 652 73.9 7.87 1 1 56931.36328 290259.5625 1 1 metabolic process extracellular;vacuole catalytic activity "Pf01301, Pf02449" 244757 ENSMUSG00000036395.15 Glb1l2 9 0 Medium Q91Y06 Protocadherin beta 13 OS=Mus musculus OX=10090 GN=Pcdhb13 PE=2 SV=1 0.017 1.114 3 1 1 1 796 87.5 4.86 1 1 146109696 135550528 111603080 87105048 1 1 1 1 cell communication;cell organization and biogenesis membrane metal ion binding "Pf00028, Pf08266" 93884 ENSMUSG00000047307.2 Pcdhb13 18 0 High A0A2I3BQZ9 Amyloid-beta A4 protein OS=Mus musculus OX=10090 GN=App PE=1 SV=1 0.012 1.397 1 1 1 1 751 84.6 4.79 1 1 356963.7188 618127.6875 194375.7813 459770.2813 1 1 1 1 0 Medium P97807 "Fumarate hydratase, mitochondrial OS=Mus musculus OX=10090 GN=Fh PE=1 SV=3" 0.016 1.126 2 1 1 1 507 54.3 9.04 1 1 122522.9922 175810.25 315392.0313 1 1 1 metabolic process cytoplasm;mitochondrion catalytic activity "Pf00206, Pf10415" 14194 ENSMUSG00000026526.14 Fh1 1 Citric acid cycle (TCA cycle) Pyruvate metabolism; Citrate cycle (TCA cycle); Metabolic pathways; Pathways in cancer; Renal cell carcinoma; Carbon metabolism 0 Medium F7BB92 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial (Fragment) OS=Mus musculus OX=10090 GN=Clpx PE=1 SV=1" 0.017 1.123 7 1 1 1 192 20.9 5.91 1 1 6826.933594 22096.74023 22206.38281 111567.3594 1 1 1 1 metabolic process;regulation of biological process membrane;mitochondrion catalytic activity;nucleotide binding;protein binding "Pf00004, Pf00158, Pf01078, Pf05729, Pf07724, Pf07726, Pf07728, Pf13191, Pf13207, Pf13401, Pf14532" ENSMUSG00000015357.10 9 0 High P62082 40S ribosomal protein S7 OS=Mus musculus OX=10090 GN=Rps7 PE=2 SV=1 0.012 1.389 11 1 1 1 194 22.1 10.1 1 1 385043.4375 1 cell differentiation;metabolic process;regulation of biological process cytoplasm;cytoskeleton;membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity Pf01251 20115 ENSMUSG00000061477.3 Rps7 12 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High A0A0R4IZY9 tRNA-dihydrouridine(47) synthase [NAD(P)(+)] OS=Mus musculus OX=10090 GN=Dus3l PE=1 SV=1 0.012 1.398 5 1 1 1 637 71.1 7.9 1 1 metabolic process catalytic activity;metal ion binding;nucleotide binding;RNA binding Pf01207 224907 ENSMUSG00000007603.8 Dus3l 17 0 High Q8R404 MICOS complex subunit MIC13 OS=Mus musculus OX=10090 GN=Micos13 PE=1 SV=1 0.012 1.354 17 1 1 1 119 13.4 8.63 1 1 189448.3438 1 cell organization and biogenesis membrane;mitochondrion 224904 ENSMUSG00000049760.5 2410015M20Rik 17 0 High A0A2R8VHK1 "Cytochrome c1, heme protein, mitochondrial (Fragment) OS=Mus musculus OX=10090 GN=Cyc1 PE=1 SV=1" 0.01 1.166 7 1 1 1 165 17.9 5.47 1 1 77384.90625 105634.6641 99523.19531 326608 1 1 1 1 0 High G3UX27 General transcription factor II-I (Fragment) OS=Mus musculus OX=10090 GN=Gtf2i PE=1 SV=1 0.011 1.272 5 1 1 1 167 18.4 4.79 1 1 222295.2188 203831.2031 165952.9531 1 1 1 metabolic process;regulation of biological process nucleus DNA binding;protein binding Pf02946 ENSMUSG00000060261.15 5 0 High A0A1B0GRU8 Pre-mRNA-processing factor 40 homolog A OS=Mus musculus OX=10090 GN=Prpf40a PE=1 SV=1 0.011 1.323 2 1 1 1 926 105.5 7.99 1 1 3626413.25 3612117.5 2164318 1686045.25 1 1 1 1 cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process cytosol;membrane;nucleus;spliceosomal complex protein binding;RNA binding "Pf00397, Pf01846" 56194 ENSMUSG00000061136.14 Prpf40a 2 0 Medium P50171 Estradiol 17-beta-dehydrogenase 8 OS=Mus musculus OX=10090 GN=Hsd17b8 PE=1 SV=2 0.017 1.105 5 1 1 1 259 26.6 6.54 1 1 477307.9688 544621.875 501385.9375 355702.1563 1 1 1 1 cell organization and biogenesis;metabolic process membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf00106, Pf08659, Pf13561" 14979 ENSMUSG00000073422.10 H2-Ke6 17 Fatty acyl-CoA biosynthesis Steroid hormone biosynthesis; Metabolic pathways 0 High A0A140T8T4 "Ribosomal protein L9, pseudogene 6 OS=Mus musculus OX=10090 GN=Rpl9-ps6 PE=4 SV=1" 0.011 1.299 6 1 1 1 192 21.8 9.88 1 1 141737.2969 150994.4375 195607.8438 1 1 1 metabolic process ribosome RNA binding;structural molecule activity Pf00347 100042823 ENSMUSG00000062456.3 Rpl9-ps6 19 0 High Q9R0P5 Destrin OS=Mus musculus OX=10090 GN=Dstn PE=1 SV=3 0.011 1.262 4 1 1 1 165 18.5 7.97 1 1 cell organization and biogenesis;cellular component movement;regulation of biological process cytoplasm;cytoskeleton protein binding Pf00241 56431 ENSMUSG00000015932.8 Dstn 2 0 High A0A075B5U7 Immunoglobulin heavy variable 1-22 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-22 PE=1 SV=1 0 2.867 9 1 1 1 117 13 8.76 1 1 447506.2188 643348.1875 421750.75 1 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000094561.1 LOC673196 12 0 High D3YYS6 Monoglyceride lipase OS=Mus musculus OX=10090 GN=Mgll PE=1 SV=1 0.012 1.396 3 1 1 1 331 36.6 7.21 1 1 128861.8594 204521.9063 1 1 metabolic process catalytic activity "Pf00561, Pf00756, Pf00975, Pf01764, Pf12146, Pf12695, Pf12697" ENSMUSG00000033174.17 6 0 Medium A0A494B968 Matrin-3 (Fragment) OS=Mus musculus OX=10090 GN=Matr3 PE=4 SV=1 0.016 1.129 15 1 1 1 60 6.1 11.55 1 1 281168.5313 222895.4531 1 1 0 Medium Z4YJS5 Agrin OS=Mus musculus OX=10090 GN=Agrn PE=1 SV=1 0.031 0.974 2 1 1 1 1151 121.8 5.44 1 1 179458.4375 61236.0625 1 1 cell communication;cell differentiation;cell organization and biogenesis;development;metabolic process;regulation of biological process;transport cell surface;cytosol;membrane enzyme regulator activity;metal ion binding;protein binding;transporter activity "Pf00050, Pf00053, Pf01390, Pf03137, Pf07648" 11603 ENSMUSG00000041936.18 Agrn 4 0 High P12970 60S ribosomal protein L7a OS=Mus musculus OX=10090 GN=Rpl7a PE=1 SV=2 0.012 1.359 3 1 1 1 266 30 10.56 1 1 740247 614126.5625 429704.0625 452244.7188 1 1 1 1 metabolic process cytoplasm;membrane;nucleus;ribosome protein binding;RNA binding Pf01248 27176 ENSMUSG00000062647.16 Rpl7a 2 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High D3YWY6 Mitochondrial pyruvate carrier OS=Mus musculus OX=10090 GN=Mpc1 PE=1 SV=1 0.013 1.506 9 1 1 1 85 9.7 9.39 1 1 43498.75 209457.4688 1 1 transport membrane;mitochondrion Pf03650 ENSMUSG00000023861.17 17 0 High Q6ZWV7 60S ribosomal protein L35 OS=Mus musculus OX=10090 GN=Rpl35 PE=1 SV=1 0 2.161 8 1 1 1 123 14.5 11.05 1 1 200335.1875 419615.4063 178391.1875 775221.3125 1 1 1 1 metabolic process;response to stimulus membrane;ribosome RNA binding;structural molecule activity Pf00831 66489 ENSMUSG00000078193.2; ENSMUSG00000062997.6 Rpl35 2; 1 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 Medium P19536 "Cytochrome c oxidase subunit 5B, mitochondrial OS=Mus musculus OX=10090 GN=Cox5b PE=1 SV=1" 0.022 1.042 6 1 1 1 128 13.8 8.38 1 1 68131.96094 640563.4375 1 1 metabolic process;transport membrane;mitochondrion catalytic activity;metal ion binding;transporter activity Pf01215 12859 Cox5b 1 0 Medium P61027 Ras-related protein Rab-10 OS=Mus musculus OX=10090 GN=Rab10 PE=1 SV=1 0.016 1.087 6 1 1 1 200 22.5 8.38 1 1 133213.9219 221598.9219 485623.375 1 1 1 cell differentiation;cell organization and biogenesis;regulation of biological process;response to stimulus;transport endoplasmic reticulum;endosome;Golgi;membrane catalytic activity;nucleotide binding;protein binding "Pf00025, Pf00071, Pf04670, Pf08477" 19325 ENSMUSG00000020671.9 Rab10 12 RAB GEFs exchange GTP for GDP on RABs; Neutrophil degranulation Endocytosis; AMPK signaling pathway 0 High G5E902 "Phosphate carrier protein, mitochondrial OS=Mus musculus OX=10090 GN=Slc25a3 PE=1 SV=1" 0.013 1.429 3 1 1 1 358 39.7 9.29 1 1 56307.84766 68973.64844 125513.3516 930876.0625 1 1 1 1 transport membrane;mitochondrion protein binding;transporter activity Pf00153 18674 ENSMUSG00000061904.12 Slc25a3 10 0 High Q91YQ5 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Mus musculus OX=10090 GN=Rpn1 PE=1 SV=1 0 2.706 2 1 1 1 608 68.5 6.46 1 1 546772.9375 1 metabolic process cytosol;endoplasmic reticulum;membrane catalytic activity;RNA binding Pf04597 103963 ENSMUSG00000030062.7 Rpn1 6 Metabolic pathways; N-Glycan biosynthesis; Protein processing in endoplasmic reticulum 0 Medium A0A0G2JG10 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Mus musculus OX=10090 GN=Dhx15 PE=1 SV=1 0.017 1.104 2 1 1 1 608 68.5 6.8 1 1 431068.5313 566246.125 244524.6875 1 1 1 catalytic activity;nucleotide binding "Pf00270, Pf00271, Pf04408, Pf13401" ENSMUSG00000029169.11 5 0 High Q9D880 Mitochondrial import inner membrane translocase subunit TIM50 OS=Mus musculus OX=10090 GN=Timm50 PE=1 SV=1 0.011 1.281 3 1 1 1 353 39.8 8.13 1 1 101394.3125 63536.47656 130984.0781 641550.75 1 1 1 1 cell organization and biogenesis;metabolic process;transport membrane;mitochondrion catalytic activity;protein binding Pf03031 66525 ENSMUSG00000003438.17 Timm50 7 0 High Q91YW3 DnaJ homolog subfamily C member 3 OS=Mus musculus OX=10090 GN=Dnajc3 PE=1 SV=1 0.009 1.63 2 1 1 1 504 57.4 5.85 1 1 49817.28125 36762.33203 233606.0469 1 1 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;endoplasmic reticulum;membrane;organelle lumen enzyme regulator activity;protein binding "Pf00226, Pf00515, Pf13371, Pf13414, Pf13424, Pf14559" 100037258 ENSMUSG00000022136.7 Dnajc3 14 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Neutrophil degranulation; Post-translational protein phosphorylation Influenza A; Protein processing in endoplasmic reticulum 0 High Q61810 Latent-transforming growth factor beta-binding protein 3 OS=Mus musculus OX=10090 GN=Ltbp3 PE=1 SV=4 0 2.678 1 1 1 1 1253 134.3 6.18 1 1 0 Medium Q9QYI6 DnaJ homolog subfamily B member 9 OS=Mus musculus OX=10090 GN=Dnajb9 PE=1 SV=2 0.017 1.094 4 1 1 1 222 25.6 8.28 1 1 509142.7188 1 metabolic process cytoplasm;endoplasmic reticulum;organelle lumen protein binding Pf00226 27362 ENSMUSG00000014905.4 Dnajb9 12 0 High Q8CGV5 Matrix metallopeptidase 28 (Epilysin) OS=Mus musculus OX=10090 GN=Mmp28 PE=1 SV=1 0.012 1.369 2 1 1 1 510 57.3 9.47 1 1 332776.5 1 metabolic process;regulation of biological process cytoplasm catalytic activity;metal ion binding "Pf00045, Pf00413, Pf01471, Pf13574, Pf13688" 118453 ENSMUSG00000020682.17 Mmp28 11 0 High Q8BPT6 Mitochondrial inner membrane protease subunit 2 OS=Mus musculus OX=10090 GN=Immp2l PE=1 SV=1 0 1.915 6 1 1 1 175 19.6 9.54 1 1 598053 1 cell organization and biogenesis;metabolic process;response to stimulus membrane;mitochondrion catalytic activity "Pf00717, Pf10502" 93757 ENSMUSG00000056899.10 Immp2l 12 Protein export 0 Medium Q9DBB9 Carboxypeptidase N subunit 2 OS=Mus musculus OX=10090 GN=Cpn2 PE=1 SV=2 0.014 1.148 2 1 1 1 547 60.4 5.88 1 1 14052.33887 22604.35156 377597.375 1 1 1 extracellular protein binding "Pf12799, Pf13306, Pf13855" 71756 ENSMUSG00000023176.8 Cpn2 16 Regulation of Complement cascade 0 High P53986 Monocarboxylate transporter 1 OS=Mus musculus OX=10090 GN=Slc16a1 PE=1 SV=1 0 3.028 3 1 1 1 493 53.2 7.47 1 1 77544.11719 83573.16406 104752.8281 919882.0625 1 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport membrane;mitochondrion protein binding;transporter activity "Pf00083, Pf07690" 20501 ENSMUSG00000032902.1 Slc16a1 3 Basigin interactions; Proton-coupled monocarboxylate transport; Pyruvate metabolism 0 High A0A1B0GQX5 L-lactate dehydrogenase OS=Mus musculus OX=10090 GN=Ldha PE=1 SV=1 0.01 1.191 4 1 1 1 201 22.1 8.54 1 1 181565.0313 26251.98633 207038.4063 1 1 1 metabolic process catalytic activity "Pf00056, Pf02866" ENSMUSG00000063229.15 7 0 High Q08857 Platelet glycoprotein 4 OS=Mus musculus OX=10090 GN=Cd36 PE=1 SV=2 0 2.527 3 1 1 1 472 52.7 8.35 1 1 162601.1406 1211564.5 1 1 cell organization and biogenesis;cellular homeostasis;defense response;metabolic process;regulation of biological process;response to stimulus;transport cell surface;endoplasmic reticulum;Golgi;membrane;mitochondrion protein binding;receptor activity;signal transducer activity Pf01130 12491 ENSMUSG00000002944.15 Cd36 5 Scavenging by Class B Receptors; Cross-presentation of particulate exogenous antigens (phagosomes); Regulation of TLR by endogenous ligand; Neutrophil degranulation; Platelet degranulation PPAR signaling pathway; Fat digestion and absorption; Insulin resistance; Phagosome; Adipocytokine signaling pathway; ECM-receptor interaction; AMPK signaling pathway; Hematopoietic cell lineage; Malaria 0 High E9Q1W3 Nebulin OS=Mus musculus OX=10090 GN=Neb PE=1 SV=1 0.013 1.418 0 1 1 1 7152 828.1 9.07 1 1 5990129 6818616.5 5331183.5 5013753 1 1 1 1 cell organization and biogenesis;regulation of biological process protein binding "Pf00880, Pf14604" 17996 ENSMUSG00000026950.17 Neb 2 Striated Muscle Contraction 0 High Q99LF4 RNA-splicing ligase RtcB homolog OS=Mus musculus OX=10090 GN=Rtcb PE=1 SV=1 0.014 1.601 2 1 1 1 505 55.2 7.23 1 1 246841.5781 161608.9219 204283.125 1 1 1 metabolic process cytoplasm;cytosol;membrane;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding;RNA binding Pf01139 28088 ENSMUSG00000001783.3 D10Wsu52e; Rtcb 10 0 Medium Q9EP72 ER membrane protein complex subunit 7 OS=Mus musculus OX=10090 GN=Emc7 PE=1 SV=1 0.022 1.035 5 1 1 1 241 26.3 9.23 1 1 368953.5938 1 membrane Pf09430 73024 ENSMUSG00000055943.5 Emc7 2 0 Medium A0A0R4J002 Nuclear receptor-binding protein 2 OS=Mus musculus OX=10090 GN=Nrbp2 PE=1 SV=1 0.028 1.018 3 1 1 1 258 29.6 6.27 1 1 184127.9219 133782.1719 1 1 cell differentiation;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol catalytic activity;nucleotide binding Pf00069 223649 ENSMUSG00000075590.2 Nrbp2 15 0 High Q64435 UDP-glucuronosyltransferase 1-6 OS=Mus musculus OX=10090 GN=Ugt1a6 PE=1 SV=1 0.01 1.153 2 1 1 1 531 60.4 8.62 1 1 77765.57031 449043.1875 1 1 metabolic process endoplasmic reticulum;membrane catalytic activity;protein binding "Pf00201, Pf04101" 94284 ENSMUSG00000090124.7; ENSMUSG00000054545.17 Ugt1a6a 1 Glucuronidation Steroid hormone biosynthesis; Drug metabolism - cytochrome P450; Retinol metabolism; Metabolic pathways; Drug metabolism - other enzymes; Ascorbate and aldarate metabolism; Chemical carcinogenesis; Porphyrin and chlorophyll metabolism; Pentose and glucuronate interconversions; Metabolism of xenobiotics by cytochrome P450 0 High Q3UHJ0 AP2-associated protein kinase 1 OS=Mus musculus OX=10090 GN=Aak1 PE=1 SV=2 0 1.84 2 1 1 1 959 103.3 6.7 1 1 286721.7813 195300.75 169750.3438 1 1 1 metabolic process;regulation of biological process;transport cytoplasm;membrane catalytic activity;nucleotide binding;protein binding "Pf00069, Pf07714" 269774 ENSMUSG00000057230.13 Aak1 6 Cargo recognition for clathrin-mediated endocytosis 0 High Q3TQC7 Ectonucleoside triphosphate diphosphohydrolase 5 OS=Mus musculus OX=10090 GN=Entpd5 PE=1 SV=1 0.013 1.535 2 1 1 1 452 49.8 5.47 1 1 72079.25781 85029.08594 216670.875 1 1 1 cell growth;cell proliferation;metabolic process;regulation of biological process endoplasmic reticulum;extracellular;membrane catalytic activity Pf01150 12499 ENSMUSG00000021236.16 Entpd5 12 0 High Q8CH09 SURP and G-patch domain-containing protein 2 OS=Mus musculus OX=10090 GN=Sugp2 PE=1 SV=2 0.011 1.261 1 1 1 1 1067 118 8.31 1 1 143452.2344 147338.3281 93120.50781 1 1 1 metabolic process nucleus RNA binding "Pf01585, Pf01805" 234373 ENSMUSG00000036054.15 Sugp2 8 0 High Q9D8B3 Charged multivesicular body protein 4b OS=Mus musculus OX=10090 GN=Chmp4b PE=1 SV=2 0 2.161 4 1 1 1 224 24.9 4.82 1 1 19801.14063 747964.4375 915394 188628.5 1 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;cytosol;endosome;membrane;nucleus protein binding Pf03357 75608 ENSMUSG00000038467.15 Chmp4b 2 Macroautophagy; Endosomal Sorting Complex Required For Transport (ESCRT) Endocytosis 0 High P84099 60S ribosomal protein L19 OS=Mus musculus OX=10090 GN=Rpl19 PE=1 SV=1 0.007 1.69 5 1 1 1 196 23.5 11.47 1 1 341325.6875 400310.5 275123.875 327385.6563 1 1 1 1 metabolic process membrane;ribosome RNA binding;structural molecule activity Pf01280 19921; 100041511 ENSMUSG00000017404.12 Rpl19; Rpl19-ps11 11; 8 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Z4YKM2 "CDGSH iron-sulfur domain-containing protein 3, mitochondrial OS=Mus musculus OX=10090 GN=Cisd3 PE=1 SV=1" 0.012 1.348 7 1 1 1 115 13.1 9.83 1 1 12392.72754 114760.1797 148351.5938 588674.125 1 1 1 1 mitochondrion metal ion binding Pf09360 217149 ENSMUSG00000078695.8 Cisd3 11 0 High Q8VIB3 "Type 2 lactosamine alpha-2,3-sialyltransferase OS=Mus musculus OX=10090 GN=St3gal6 PE=2 SV=3" 0.007 1.675 5 1 1 1 329 37.8 9.16 1 1 64666.33984 1 metabolic process;response to stimulus Golgi;membrane catalytic activity Pf00777 54613 ENSMUSG00000022747.16 St3gal6 16 Keratan sulfate biosynthesis; Sialic acid metabolism Metabolic pathways; Glycosphingolipid biosynthesis - lacto and neolacto series 0 High Q8C190 VPS9 domain-containing protein 1 OS=Mus musculus OX=10090 GN=Vps9d1 PE=1 SV=1 0.011 1.275 3 1 1 1 649 71.2 6.87 1 1 Pf02204 72325 ENSMUSG00000001062.18 1300018I17Rik; Vps9d1 8 0 High D6REG4 Glyoxylate reductase/hydroxypyruvate reductase OS=Mus musculus OX=10090 GN=Grhpr PE=1 SV=1 0.012 1.4 6 1 1 1 197 21.2 7.8 1 1 23025.37695 78813.02344 43615.03906 285562.5625 1 1 1 1 metabolic process catalytic activity;nucleotide binding "Pf00389, Pf02826" ENSMUSG00000035637.14 4 0 High P01867 Ig gamma-2B chain C region OS=Mus musculus OX=10090 GN=Igh-3 PE=1 SV=3 0.01 1.215 4 1 1 1 404 44.2 6.52 1 1 615532.25 754512.9375 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus extracellular;membrane protein binding Pf07654 16016 Ighg2b 12 0 High Q8BUE4 Ferroptosis suppressor protein 1 OS=Mus musculus OX=10090 GN=Aifm2 PE=1 SV=1 0.013 1.574 3 1 1 1 373 40.6 8.98 1 1 142811.4531 87630.51563 683595 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;cytosol;membrane;mitochondrion catalytic activity;DNA binding;nucleotide binding "Pf00070, Pf07992" 71361 ENSMUSG00000020085.15 Aifm2 10 0 High E0CXN5 Glycerol-3-phosphate dehydrogenase [NAD(+)] OS=Mus musculus OX=10090 GN=Gpd1 PE=1 SV=1 0.01 1.215 3 1 1 1 326 35.2 7.59 1 1 450608.875 336714.4063 288713.125 351051.0313 1 1 1 1 metabolic process;regulation of biological process;response to stimulus;transport mitochondrion catalytic activity;nucleotide binding;protein binding "Pf01210, Pf07479" ENSMUSG00000023019.12 15 0 High H3BK03 Serum paraoxonase/arylesterase 1 (Fragment) OS=Mus musculus OX=10090 GN=Pon1 PE=1 SV=9 0.013 1.483 5 1 1 1 256 28.7 5.45 1 1 174347.8438 1045097.813 1 1 0 High F6VVY4 "Tricarboxylate transport protein, mitochondrial (Fragment) OS=Mus musculus OX=10090 GN=Slc25a1 PE=1 SV=1" 0 2.037 6 1 1 1 197 21.5 9.8 1 1 643745.375 1 transport membrane;mitochondrion Pf00153 ENSMUSG00000003528.14 16 0 High Q8R2R1 Protein O-mannosyl-transferase 1 OS=Mus musculus OX=10090 GN=Pomt1 PE=1 SV=1 0.01 1.245 2 1 1 1 746 85.2 8.29 1 1 505541.0313 1 cell organization and biogenesis;metabolic process;response to stimulus endoplasmic reticulum;membrane catalytic activity "Pf02366, Pf02815, Pf13231" 99011 ENSMUSG00000039254.16 Pomt1 2 O-linked glycosylation Other types of O-glycan biosynthesis 0 High P41105 60S ribosomal protein L28 OS=Mus musculus OX=10090 GN=Rpl28 PE=1 SV=2 0.01 1.162 8 1 1 1 137 15.7 12.02 1 1 361529.4375 582457.875 282190.4375 323788.3125 1 1 1 1 metabolic process;regulation of biological process membrane;ribosome RNA binding;structural molecule activity Pf01778 19943 ENSMUSG00000030432.12 Rpl28 7 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High P47757 F-actin-capping protein subunit beta OS=Mus musculus OX=10090 GN=Capzb PE=1 SV=3 0.011 1.258 5 1 1 1 277 31.3 5.74 1 1 118941.4766 82756.77344 163668.2188 1 1 1 cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton;membrane protein binding Pf01115 12345 ENSMUSG00000028745.18 Capzb 4 COPI-independent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; MHC class II antigen presentation; Factors involved in megakaryocyte development and platelet production; HSP90 chaperone cycle for steroid hormone receptors (SHR) Endocytosis 0 High P01029 Complement C4-B OS=Mus musculus OX=10090 GN=C4b PE=1 SV=3 0 1.891 0 1 1 1 1738 192.8 7.53 1 1 301066.1875 853037.875 755110.875 1 1 1 defense response;metabolic process;regulation of biological process;response to stimulus extracellular enzyme regulator activity;protein binding "Pf00207, Pf01759, Pf01821, Pf01835, Pf07677, Pf07678, Pf07703, Pf10569, Pf11974, Pf13249" 12268 ENSMUSG00000073418.4 C4b 17 Regulation of Complement cascade; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Activation of C3 and C5; Post-translational protein phosphorylation; Initial triggering of complement Staphylococcus aureus infection; Complement and coagulation cascades; Pertussis; Systemic lupus erythematosus 0 High Q91WS0 CDGSH iron-sulfur domain-containing protein 1 OS=Mus musculus OX=10090 GN=Cisd1 PE=1 SV=1 0.014 1.608 12 1 1 1 108 12.1 9.06 1 1 269486.5313 1 regulation of biological process membrane;mitochondrion metal ion binding;protein binding Pf09360 52637 ENSMUSG00000037710.8 Cisd1 10 0 Medium Q9ER05 Chymopasin OS=Mus musculus OX=10090 GN=Ctrl PE=1 SV=1 0.031 0.973 5 1 1 1 264 28.1 8.35 1 1 1294872.75 514292.2813 118358.6328 93495.57813 1 1 1 1 metabolic process catalytic activity "Pf00089, Pf09342" 109660 ENSMUSG00000031896.7 Ctrl 8 Pancreatic secretion; Protein digestion and absorption 0 High P83093 Stromal interaction molecule 2 OS=Mus musculus OX=10090 GN=Stim2 PE=1 SV=2 0 2.428 1 1 1 1 746 83.9 6.79 1 1 275995.0313 1 cellular homeostasis;regulation of biological process;transport endoplasmic reticulum;membrane metal ion binding;protein binding;transporter activity "Pf00536, Pf07647, Pf13868" 116873 ENSMUSG00000039156.19 Stim2 5 Calcium signaling pathway 0 High A0A0R4J0Z1 Protein disulfide-isomerase A4 OS=Mus musculus OX=10090 GN=Pdia4 PE=1 SV=1 0.012 1.331 2 1 1 1 641 72.3 5.22 1 1 380520 1 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cell surface;endoplasmic reticulum;organelle lumen catalytic activity;metal ion binding;RNA binding "Pf00085, Pf01216, Pf13098, Pf13848, Pf13905" 12304 ENSMUSG00000025823.9 Pdia4 6 Thyroid hormone synthesis; Protein processing in endoplasmic reticulum 0 High Q99M74 "Keratin, type II cuticular Hb2 OS=Mus musculus OX=10090 GN=Krt82 PE=1 SV=2" 0.01 1.237 2 1 1 1 516 57.1 6.25 1 1 269152.8125 1019636.813 78771.57031 1 1 1 structural molecule activity Pf00038 114566 ENSMUSG00000049548.8 Krt82 15 Formation of the cornified envelope 0 High Q99JB2 "Stomatin-like protein 2, mitochondrial OS=Mus musculus OX=10090 GN=Stoml2 PE=1 SV=1" 0.01 1.184 4 1 1 1 353 38.4 8.87 1 1 1764344.375 185876.5313 429228.1875 357667.1563 1 1 1 1 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;membrane;mitochondrion protein binding Pf01145 66592 ENSMUSG00000028455.15 Stoml2 4 Processing of SMDT1 0 High Q9CQ10 Charged multivesicular body protein 3 OS=Mus musculus OX=10090 GN=Chmp3 PE=1 SV=3 0.011 1.284 4 1 1 1 224 25.2 5.06 1 1 139099 356066.9375 35648.50391 1 1 1 cell division;cell organization and biogenesis;regulation of biological process;transport cytoplasm;cytosol;endosome;membrane protein binding Pf03357 66700 ENSMUSG00000053119.11 Chmp3 6 Macroautophagy; Endosomal Sorting Complex Required For Transport (ESCRT) Endocytosis 0 High P62843 40S ribosomal protein S15 OS=Mus musculus OX=10090 GN=Rps15 PE=1 SV=2 0 3.781 9 1 1 1 145 17 10.39 1 1 339483 901143 1 1 cell differentiation;cell organization and biogenesis;metabolic process;transport membrane;ribosome protein binding;RNA binding;structural molecule activity Pf00203 20054 ENSMUSG00000063457.14 Rps15 10 Ribosome 0 Medium O54991 Contactin-associated protein 1 OS=Mus musculus OX=10090 GN=Cntnap1 PE=1 SV=2 0.016 1.137 1 1 1 1 1385 156.2 7.06 1 1 406484.125 1 cell organization and biogenesis membrane protein binding "Pf00054, Pf00147, Pf00754, Pf02210" 53321 ENSMUSG00000017167.6 Cntnap1 11 Cell adhesion molecules (CAMs) 0 Medium O08528 Hexokinase-2 OS=Mus musculus OX=10090 GN=Hk2 PE=1 SV=1 0.017 1.101 1 1 1 1 917 102.5 6.11 1 1 15552.96094 86869.95313 359492.1875 1 1 1 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytosol;membrane;mitochondrion catalytic activity;nucleotide binding;protein binding "Pf00349, Pf03727" 15277 ENSMUSG00000000628.10 Hk2 6 Glycolysis "Neomycin, kanamycin and gentamicin biosynthesis; Type II diabetes mellitus; Carbohydrate digestion and absorption; Insulin signaling pathway; Metabolic pathways; Amino sugar and nucleotide sugar metabolism; Starch and sucrose metabolism; Glycolysis / Gluconeogenesis; HIF-1 signaling pathway; Carbon metabolism; Fructose and mannose metabolism; Galactose metabolism; Central carbon metabolism in cancer" 0 High Q9CPR4 60S ribosomal protein L17 OS=Mus musculus OX=10090 GN=Rpl17 PE=1 SV=3 0.014 1.595 5 1 1 1 184 21.4 10.18 1 1 572195.875 370788.9375 401560.2813 1 1 1 metabolic process;regulation of biological process nucleus;ribosome protein binding;RNA binding;structural molecule activity Pf00237 319195 Rpl17 18 0 Medium P29788 Vitronectin OS=Mus musculus OX=10090 GN=Vtn PE=1 SV=2 0.026 1.022 2 1 1 1 478 54.8 5.88 1 1 208681.6875 235041.5625 691588.9375 1 1 1 cell differentiation;cell organization and biogenesis;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;extracellular;organelle lumen protein binding;receptor activity "Pf00045, Pf01033" 22370 ENSMUSG00000017344.4 Vtn 11 Regulation of Complement cascade; ECM proteoglycans; Molecules associated with elastic fibres; Syndecan interactions; Integrin cell surface interactions Focal adhesion; Complement and coagulation cascades; Proteoglycans in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway 0 Medium A0A1B0GRM0 Retinoblastoma-like protein 2 OS=Mus musculus OX=10090 GN=Rbl2 PE=1 SV=1 0.032 0.999 1 1 1 1 1092 122.6 7.74 1 1 782407.5 442396.75 371803.8438 500445.8125 1 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process chromosome;cytosol;nucleus DNA binding;protein binding "Pf01857, Pf01858, Pf11934" 19651 ENSMUSG00000031666.15 Rbl2 8 0 Medium D3YVC9 Graves disease carrier protein homolog (Fragment) OS=Mus musculus OX=10090 GN=Slc25a16 PE=1 SV=1 0.022 1.039 2 1 1 1 322 34.9 9.95 1 1 239689.1406 1 transport membrane;mitochondrion Pf00153 ENSMUSG00000071253.8 10 0 Medium Q3UVK0 Endoplasmic reticulum metallopeptidase 1 OS=Mus musculus OX=10090 GN=Ermp1 PE=1 SV=2 0.022 1.043 1 1 1 1 898 100.1 7.49 1 1 268531.7188 1 metabolic process endoplasmic reticulum;membrane catalytic activity;metal ion binding "Pf04389, Pf14264" 226090 ENSMUSG00000046324.12 Ermp1 19 0 Medium Q9CQ69 Cytochrome b-c1 complex subunit 8 OS=Mus musculus OX=10090 GN=Uqcrq PE=1 SV=3 0.032 1.004 16 1 1 1 82 9.8 10.26 1 1 257470.2969 203607.2969 643991.5 1 1 1 metabolic process;transport membrane;mitochondrion catalytic activity;transporter activity Pf02939 22272 ENSMUSG00000044894.14 Uqcrq 11 Respiratory electron transport Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 High P14115 60S ribosomal protein L27a OS=Mus musculus OX=10090 GN=Rpl27a PE=1 SV=5 0.012 1.414 7 1 1 1 148 16.6 11.12 1 1 544034.5625 666009.75 482125.8125 810044.6875 1 1 1 1 metabolic process cytosol;endoplasmic reticulum;membrane;ribosome RNA binding;structural molecule activity Pf00828 26451 ENSMUSG00000046364.14 Rpl27a 7 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High A0A0R4J0D3 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Mus musculus OX=10090 GN=Stt3b PE=1 SV=1 0.011 1.299 1 1 1 1 823 93.3 9 1 1 493339.9688 1 Met-loss+Acetyl [N-Term] metabolic process;response to stimulus endoplasmic reticulum;membrane catalytic activity;metal ion binding "Pf02516, Pf13231" 68292 ENSMUSG00000032437.10 Stt3b 9 Metabolic pathways; N-Glycan biosynthesis; Protein processing in endoplasmic reticulum 0 High Q6PKB0 Fcgrt protein OS=Mus musculus OX=10090 GN=Fcgrt PE=1 SV=1 0.013 1.474 2 1 1 1 369 40.5 5.54 1 1 248825.2813 1 membrane protein binding;receptor activity;signal transducer activity "Pf00129, Pf07654" 14132 ENSMUSG00000003420.8 Fcgrt 7 0 High E9Q3X6 Amine oxidase OS=Mus musculus OX=10090 GN=Maob PE=1 SV=1 0 3.507 7 1 1 1 211 23.7 8.62 1 1 3600.654053 409559.6875 1 1 metabolic process membrane;mitochondrion catalytic activity "Pf01593, Pf13450" ENSMUSG00000040147.14 X 0 High Q02257 Junction plakoglobin OS=Mus musculus OX=10090 GN=Jup PE=1 SV=3 0.01 1.191 2 1 1 1 745 81.7 6.14 1 1 124315.5078 236415.5313 411962.125 1 1 1 cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;nucleus protein binding;signal transducer activity;structural molecule activity Pf00514 16480 ENSMUSG00000001552.14 Jup 11 Formation of the cornified envelope; VEGFR2 mediated vascular permeability; Neutrophil degranulation; Adherens junctions interactions Acute myeloid leukemia; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Transcriptional misregulation in cancer; Pathways in cancer 0 High Q8CC88 von Willebrand factor A domain-containing protein 8 OS=Mus musculus OX=10090 GN=Vwa8 PE=1 SV=2 0.01 1.149 1 1 1 1 1905 213.3 6.6 1 1 192330.2969 141777.1563 112086.2578 430963.4063 1 1 1 1 extracellular;mitochondrion catalytic activity;nucleotide binding "Pf00092, Pf07728, Pf13191, Pf13519, Pf13521" 219189 ENSMUSG00000058997.7 Vwa8 14 0 High P46412 Glutathione peroxidase 3 OS=Mus musculus OX=10090 GN=Gpx3 PE=1 SV=2 0.014 1.622 5 1 1 1 226 25.4 8.22 1 1 38136.92188 413008.5938 1 1 cell organization and biogenesis;metabolic process;response to stimulus extracellular antioxidant activity;catalytic activity Pf00255 14778 ENSMUSG00000018339.11 Gpx3 11 Detoxification of Reactive Oxygen Species Glutathione metabolism; Thyroid hormone synthesis; Arachidonic acid metabolism 0 High F8WJ41 40S ribosomal protein S15a (Fragment) OS=Mus musculus OX=10090 GN=Rps15a PE=1 SV=1 0.012 1.407 8 1 1 1 108 12.3 10.15 1 1 112524.75 288394.9688 155508.5781 624980.75 1 1 1 1 metabolic process mitochondrion;ribosome structural molecule activity Pf00410 ENSMUSG00000008683.16 7 0 High H7BXC3 Triosephosphate isomerase OS=Mus musculus OX=10090 GN=Tpi1 PE=1 SV=1 0.012 1.358 7 1 1 1 167 18 5.58 1 1 118518.7266 111736.8203 197127.125 1 1 1 development;metabolic process catalytic activity Pf00121 ENSMUSG00000023456.14 6 0 Medium A2AWH7 "Pyruvate dehydrogenase protein X component, mitochondrial (Fragment) OS=Mus musculus OX=10090 GN=Pdhx PE=1 SV=1" 0.017 1.093 6 1 1 1 218 23 6.34 1 1 984674.6875 173417.2813 166034.8125 243064.8281 1 1 1 1 metabolic process mitochondrion catalytic activity "Pf00364, Pf02817" 27402 ENSMUSG00000010914.10 Pdhx 2 0 High P10922 Histone H1.0 OS=Mus musculus OX=10090 GN=H1-0 PE=2 SV=4 0 2.329 5 1 1 1 194 20.8 10.9 1 1 732588.6875 389915.5313 446072.9375 1 1 1 cell organization and biogenesis chromosome;cytoskeleton;Golgi;nucleus DNA binding;RNA binding Pf00538 14958 ENSMUSG00000096210.1 H1f0 15 Activation of DNA fragmentation factor; Formation of Senescence-Associated Heterochromatin Foci (SAHF) 0 High P46978 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Mus musculus OX=10090 GN=Stt3a PE=1 SV=1 0.012 1.375 1 1 1 1 705 80.5 8.1 1 1 1328461.625 1 metabolic process endoplasmic reticulum;membrane catalytic activity;metal ion binding Pf02516 16430 ENSMUSG00000032116.18 Stt3a 9 Metabolic pathways; N-Glycan biosynthesis; Protein processing in endoplasmic reticulum 0 Medium P63276 40S ribosomal protein S17 OS=Mus musculus OX=10090 GN=Rps17 PE=1 SV=2 0.018 1.06 7 1 1 1 135 15.5 9.85 1 1 cell organization and biogenesis;metabolic process membrane;ribosome RNA binding;structural molecule activity Pf00833 20068 ENSMUSG00000061787.15 Rps17 7 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High Q9CXE7 Transmembrane emp24 domain-containing protein 5 OS=Mus musculus OX=10090 GN=Tmed5 PE=1 SV=1 0 1.816 5 1 1 1 229 26.2 4.93 1 1 213770.4375 1 cell organization and biogenesis;transport endoplasmic reticulum;Golgi;membrane Pf01105 73130 ENSMUSG00000063406.11 Tmed5 5 WNT ligand biogenesis and trafficking 0 High P51660 Peroxisomal multifunctional enzyme type 2 OS=Mus musculus OX=10090 GN=Hsd17b4 PE=1 SV=3 0 1.919 2 1 1 1 735 79.4 8.57 1 1 205827.4063 142696.75 109940.7188 110541.875 1 1 1 1 cell differentiation;metabolic process membrane;mitochondrion catalytic activity;protein binding "Pf00106, Pf01575, Pf02036, Pf08659, Pf13452, Pf13561, Pf14864" 15488 ENSMUSG00000024507.6 Hsd17b4 18 Beta-oxidation of pristanoyl-CoA; Beta-oxidation of very long chain fatty acids; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; alpha-linolenic acid (ALA) metabolism Metabolic pathways; Primary bile acid biosynthesis; Peroxisome 0 High A0A140T8P1 Immunoglobulin kappa variable 6-14 (Fragment) OS=Mus musculus OX=10090 GN=Igkv6-14 PE=4 SV=2 0.01 1.245 8 1 1 1 115 12.8 6.51 1 1 488889.2188 1 structural molecule activity "Pf00047, Pf01410, Pf07679, Pf07686" 667881 ENSMUSG00000096844.1 Igkv6-14 6 0 Medium P98086 Complement C1q subcomponent subunit A OS=Mus musculus OX=10090 GN=C1qa PE=1 SV=2 0.032 1.001 4 1 1 1 245 26 9.11 1 1 1463419.25 299057.4375 373239.8125 1063862.5 1 1 1 1 defense response;metabolic process;regulation of biological process;response to stimulus extracellular;membrane protein binding "Pf00229, Pf00386" 12259 ENSMUSG00000036887.5 C1qa 4 Regulation of Complement cascade; Classical antibody-mediated complement activation Chagas disease (American trypanosomiasis); Staphylococcus aureus infection; Complement and coagulation cascades; Pertussis; Prion diseases; Systemic lupus erythematosus 0 High F6SH71 BTB/POZ domain-containing protein KCTD2 (Fragment) OS=Mus musculus OX=10090 GN=Kctd2 PE=1 SV=1 0.012 1.353 4 1 1 1 278 30.1 5.29 1 1 390751.375 317792.25 279574.8125 1 1 1 cell organization and biogenesis protein binding Pf02214 ENSMUSG00000016940.18 11 0 High Q6ZQI3 Malectin OS=Mus musculus OX=10090 GN=Mlec PE=1 SV=2 0 2.334 4 1 1 1 291 32.3 6.05 1 1 50218.58203 99702.00781 1081197.25 1 1 1 metabolic process endoplasmic reticulum;membrane protein binding Pf11721 109154 ENSMUSG00000048578.11 Mlec 5 N-glycan trimming in the ER and Calnexin/Calreticulin cycle; Neutrophil degranulation 0 High P01746 Ig heavy chain V region 93G7 OS=Mus musculus OX=10090 PE=2 SV=1 0 1.938 7 1 1 1 140 15.5 8.4 1 1 447506.2188 643348.1875 421750.75 1 1 1 Pf07686 238440 LOC238440 12 0 High Q9Z2I8 "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial OS=Mus musculus OX=10090 GN=Suclg2 PE=1 SV=3" 0.012 1.393 2 1 1 1 433 46.8 7.02 1 1 31506.86328 35407.41797 257248.125 1 1 1 metabolic process membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00549, Pf01071, Pf08442, Pf13549" 20917 ENSMUSG00000061838.7 Suclg2 6 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Propanoate metabolism; Carbon metabolism 0 High Q9EQH2 Endoplasmic reticulum aminopeptidase 1 OS=Mus musculus OX=10090 GN=Erap1 PE=1 SV=2 0 1.887 1 1 1 1 930 106.5 6.2 1 1 cell communication;metabolic process;regulation of biological process;response to stimulus cytoplasm;endoplasmic reticulum;extracellular;membrane;organelle lumen catalytic activity;metal ion binding;protein binding "Pf01433, Pf11838, Pf13485" 80898 ENSMUSG00000021583.6 Erap1 13 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC" 0 High Q9Z1A1 TFG protein OS=Mus musculus OX=10090 GN=Tfg PE=1 SV=1 0 1.706 3 1 1 1 397 43 5.1 1 1 32618.51758 479321.25 918817.75 1 1 1 cell organization and biogenesis;regulation of biological process;response to stimulus;transport membrane protein binding;signal transducer activity "Pf00564, Pf08232" 21787 ENSMUSG00000022757.18 Tfg 16 COPII (Coat Protein 2) Mediated Vesicle Transport 0 High Q61838 Pregnancy zone protein OS=Mus musculus OX=10090 GN=Pzp PE=1 SV=3 0 1.766 1 1 1 1 1495 165.7 6.68 1 1 101121.2188 319806.4688 739007.375 1 1 1 regulation of biological process extracellular enzyme regulator activity;protein binding "Pf00207, Pf01835, Pf07677, Pf07678, Pf07703, Pf10569, Pf11974, Pf13249" 11287 ENSMUSG00000030359.14 Pzp 6 0 High Q99JR5 Tubulointerstitial nephritis antigen-like OS=Mus musculus OX=10090 GN=Tinagl1 PE=1 SV=1 0.011 1.326 3 1 1 1 466 52.6 6.77 1 1 550574.4375 242207.6719 295514.75 319718.0938 1 1 1 1 metabolic process;response to stimulus;transport cytoplasm;extracellular;vacuole catalytic activity;protein binding;receptor activity "Pf00112, Pf01033" 94242 ENSMUSG00000028776.14 Tinagl1 4 0 High Q3TU25 Probable ATP-dependent RNA helicase DDX17 OS=Mus musculus OX=10090 GN=Ddx17 PE=1 SV=1 0.013 1.417 3 1 1 1 418 47.4 8.02 1 1 275662.125 312122.8125 378630.625 396380.4688 1 1 1 1 cell differentiation;cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00270, Pf00271" 67040 Ddx17 15 0 Medium P01592 Immunoglobulin J chain OS=Mus musculus OX=10090 GN=Jchain PE=1 SV=4 0.032 0.976 5 1 1 1 159 18 4.89 1 1 289138.4688 284083.625 119458.6406 1 1 1 defense response;regulation of biological process;response to stimulus extracellular DNA binding;protein binding Pf15097 16069 ENSMUSG00000067149.6 Igj; Jchain 5 Cell surface interactions at the vascular wall; Scavenging of heme from plasma 0 Medium F8WJG3 Transformer-2 protein homolog beta OS=Mus musculus OX=10090 GN=Tra2b PE=1 SV=1 0.017 1.125 5 1 1 1 188 21.9 10.15 1 1 470754.6563 215380.9844 188289.4688 197096.0469 1 1 1 1 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus membrane;nucleus;spliceosomal complex protein binding;RNA binding "Pf00076, Pf08777, Pf13893, Pf14259" 20462 ENSMUSG00000022858.15 Tra2b 16 0 High Q9EPR2 Group XIIA secretory phospholipase A2 OS=Mus musculus OX=10090 GN=Pla2g12a PE=1 SV=2 0 1.802 5 1 1 1 192 21.3 7.15 1 1 510578.125 1 metabolic process;transport cytoplasm;endoplasmic reticulum;extracellular;Golgi catalytic activity;metal ion binding Pf06951 66350 ENSMUSG00000027999.15 Pla2g12a 3 Acyl chain remodelling of PI; Acyl chain remodelling of PG; Acyl chain remodelling of PC; Synthesis of PA; Acyl chain remodelling of PS; Acyl chain remodelling of PE Pancreatic secretion; Ras signaling pathway; Fat digestion and absorption; Metabolic pathways; Linoleic acid metabolism; Ether lipid metabolism; Glycerophospholipid metabolism; alpha-Linolenic acid metabolism; Vascular smooth muscle contraction; Arachidonic acid metabolism 0 High Q6P8I6 "Cytochrome c oxidase assembly protein COX11, mitochondrial OS=Mus musculus OX=10090 GN=Cox11 PE=1 SV=1" 0.01 1.169 10 1 1 1 275 30.8 8.78 1 1 regulation of biological process membrane;mitochondrion metal ion binding;protein binding Pf04442 69802 ENSMUSG00000020544.14 Cox11 11 Metabolic pathways; Oxidative phosphorylation 0 High Q9CR62 Mitochondrial 2-oxoglutarate/malate carrier protein OS=Mus musculus OX=10090 GN=Slc25a11 PE=1 SV=3 0.01 1.149 3 1 1 1 314 34.1 9.94 1 1 64851 642669.125 1 1 transport membrane;mitochondrion;nucleus RNA binding;transporter activity Pf00153 67863 ENSMUSG00000014606.14 Slc25a11 11 Gluconeogenesis 0 Medium Q6P6L6 Gem (Nuclear organelle) associated protein 4 OS=Mus musculus OX=10090 GN=Gemin4 PE=1 SV=1 0.026 1.021 1 1 1 1 1058 120.1 5.15 1 1 318854.6875 202504.8906 195212.3906 1 1 1 cell organization and biogenesis;metabolic process cytosol;membrane 276919 ENSMUSG00000049396.6 Gemin4 11 snRNP Assembly RNA transport 0 High B1AU25 "Apoptosis-inducing factor 1, mitochondrial OS=Mus musculus OX=10090 GN=Aifm1 PE=1 SV=1" 0 2.372 2 1 1 1 608 66.1 9.11 1 1 600638.9375 209091.4531 221619.8594 647079 1 1 1 1 cell death;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;DNA binding;nucleotide binding;protein binding "Pf00070, Pf07992, Pf14721, Pf14962" 26926 ENSMUSG00000036932.14 Aifm1 X 0 High A0A0R4J1J1 Probable hydrolase PNKD OS=Mus musculus OX=10090 GN=Pnkd PE=1 SV=1 0 3.052 8 1 1 1 142 15.6 10.27 1 1 46652.68359 386597.6875 1 1 metabolic process;regulation of biological process cytoplasm;membrane;mitochondrion;nucleus catalytic activity;metal ion binding;protein binding 56695 ENSMUSG00000026179.14 Pnkd 1 0 Medium Q1W617 Protein Shroom4 OS=Mus musculus OX=10090 GN=Shroom4 PE=1 SV=1 0.032 1.013 1 1 1 1 1475 163.1 6.73 1 1 605058.4375 499620.8125 1 1 cell organization and biogenesis;development cytoplasm;cytoskeleton;membrane protein binding "Pf00595, Pf08687" 208431 ENSMUSG00000068270.15 Shroom4 X Tight junction 0