Protein FDR Confidence: Combined Accession Description Exp. q-value: Combined Sum PEP Score Coverage [%] # Peptides # PSMs # Unique Peptides # AAs MW [kDa] calc. pI # Peptides (by Search Engine): A2 Sequest HT (IgG) # Peptides (by Search Engine): B2 Sequest HT (SKO) # Peptides (by Search Engine): C2 Sequest HT (WT) # Peptides (by Search Engine): D2 Sequest HT (HKO) # PSMs (by Search Engine): A2 Sequest HT (IgG) # PSMs (by Search Engine): B2 Sequest HT (SKO) # PSMs (by Search Engine): C2 Sequest HT (WT) # PSMs (by Search Engine): D2 Sequest HT (HKO) "Abundance: F1: Sample, IgG" "Abundance: F2: Sample, SKO" "Abundance: F3: Sample, WT" "Abundance: F4: Sample, HKO" "Abundances Count: F1: Sample, IgG" "Abundances Count: F2: Sample, SKO" "Abundances Count: F3: Sample, WT" "Abundances Count: F4: Sample, HKO" Modifications Biological Process Cellular Component Molecular Function Pfam IDs Entrez Gene ID Ensembl Gene ID Gene Symbol Chromosome Reactome Pathways KEGG Pathways # Razor Peptides High E9PZ16 Basement membrane-specific heparan sulfate proteoglycan core protein OS=Mus musculus OX=10090 GN=Hspg2 PE=1 SV=1 0 2148.481 71 199 1586 46 4383 469.5 6.47 196 153 144 114 760 308 314 204 6955558212 3778880229 3854056190 2793302039 238 195 190 158 cell differentiation;cell organization and biogenesis;transport extracellular metal ion binding;protein binding "Pf00008, Pf00047, Pf00052, Pf00053, Pf00054, Pf00057, Pf02210, Pf07679, Pf07686, Pf12785, Pf13385, Pf13895, Pf13927" 15530 ENSMUSG00000028763.17 Hspg2 4 HS-GAG degradation; A tetrasaccharide linker sequence is required for GAG synthesis; Laminin interactions; Degradation of the extracellular matrix; Signaling by GPCR; Retinoid metabolism and transport; Integrin cell surface interactions; HS-GAG biosynthesis; Non-integrin membrane-ECM interactions Hepatitis B; Proteoglycans in cancer; ECM-receptor interaction 192 High Q05793 Basement membrane-specific heparan sulfate proteoglycan core protein OS=Mus musculus OX=10090 GN=Hspg2 PE=1 SV=1 0 1607.896 60 154 1241 1 3707 398 6.32 152 120 115 90 584 243 251 163 1371034.5 1976815.375 2160687.25 1 1 1 cell differentiation;cell organization and biogenesis;transport extracellular;organelle lumen metal ion binding;protein binding "Pf00008, Pf00047, Pf00052, Pf00053, Pf00054, Pf00057, Pf02210, Pf07679, Pf07686, Pf12785, Pf13385, Pf13895, Pf13927" 15530 Hspg2 4 Hepatitis B; Proteoglycans in cancer; ECM-receptor interaction 0 High P20029 Endoplasmic reticulum chaperone BiP OS=Mus musculus OX=10090 GN=Hspa5 PE=1 SV=3 0 840.454 81 65 1226 63 655 72.4 5.16 23 47 29 65 30 115 46 1035 156982755.1 1452005673 576880050.7 57860868652 51 62 44 102 cell communication;cell death;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;endoplasmic reticulum;extracellular;membrane;mitochondrion;nucleus;organelle lumen catalytic activity;nucleotide binding;protein binding "Pf00012, Pf01968, Pf06723" 14828 ENSMUSG00000026864.13 Hspa5 2 Thyroid hormone synthesis; Antigen processing and presentation; Protein export; Prion diseases; Protein processing in endoplasmic reticulum 3 High Q9Z2G6 Protein sel-1 homolog 1 OS=Mus musculus OX=10090 GN=Sel1l PE=1 SV=2 0 1054.237 86 57 1121 57 790 88.3 5.57 22 34 56 55 135 931 73321242.38 655776070.9 3014026060 24813466639 24 43 60 86 metabolic process;regulation of biological process;response to stimulus;transport endoplasmic reticulum;membrane protein binding "Pf00040, Pf08238" 20338 ENSMUSG00000020964.14 Sel1l 12 Hedgehog ligand biogenesis; ABC-family proteins mediated transport; ER Quality Control Compartment (ERQC) Protein processing in endoplasmic reticulum 0 High P08113 Endoplasmin OS=Mus musculus OX=10090 GN=Hsp90b1 PE=1 SV=2 0 798.638 71 74 1058 72 802 92.4 4.82 6 15 11 74 7 25 14 1012 161230528.4 338042771.1 204306606.5 38151536030 28 34 27 107 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytosol;endoplasmic reticulum;extracellular;membrane;nucleus;organelle lumen nucleotide binding;protein binding;RNA binding "Pf00183, Pf02518, Pf13589" 22027 ENSMUSG00000020048.13 Hsp90b1 10 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Scavenging by Class A Receptors; Trafficking and processing of endosomal TLR Thyroid hormone synthesis; Pathways in cancer; PI3K-Akt signaling pathway; Protein processing in endoplasmic reticulum; Estrogen signaling pathway; Prostate cancer 4 High F8VPN4 4-alpha-glucanotransferase OS=Mus musculus OX=10090 GN=Agl PE=1 SV=1 0 974.844 81 105 845 105 1532 174.2 6.74 100 95 44 82 344 247 64 190 2582081783 2898333279 450519549 2345261707 120 110 74 100 metabolic process;response to stimulus cytoplasm;endoplasmic reticulum;nucleus catalytic activity;protein binding "Pf00128, Pf06202, Pf14699, Pf14701, Pf14702" 77559 ENSMUSG00000033400.14 Agl 3 Glycogen breakdown (glycogenolysis); Neutrophil degranulation Metabolic pathways; Starch and sucrose metabolism 0 High Q8K2C7 Protein OS-9 OS=Mus musculus OX=10090 GN=Os9 PE=1 SV=2 0 822.551 76 62 707 62 672 76.1 4.84 20 38 62 29 96 582 2762803.609 295063174.8 993558082.6 20975058718 7 34 48 80 metabolic process;response to stimulus;transport endoplasmic reticulum;organelle lumen protein binding "Pf07915, Pf13015" 216440 ENSMUSG00000040462.13 Os9 10 Hedgehog ligand biogenesis; ABC-family proteins mediated transport; ER Quality Control Compartment (ERQC) Protein processing in endoplasmic reticulum 0 High Q8BMS1 "Trifunctional enzyme subunit alpha, mitochondrial OS=Mus musculus OX=10090 GN=Hadha PE=1 SV=1" 0 597.072 72 51 610 51 763 82.6 9.14 48 46 41 47 223 133 113 141 2884484623 2439108120 2437766385 4002823454 63 57 56 61 metabolic process;response to stimulus membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding;protein binding "Pf00378, Pf00725, Pf02737" 97212 ENSMUSG00000025745.11 Hadha 5 Beta oxidation of myristoyl-CoA to lauroyl-CoA; Acyl chain remodeling of CL; Beta oxidation of palmitoyl-CoA to myristoyl-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA "Fatty acid metabolism; Tryptophan metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Lysine degradation; Fatty acid degradation; Butanoate metabolism; beta-Alanine metabolism; Propanoate metabolism; Fatty acid elongation; Carbon metabolism; Biosynthesis of unsaturated fatty acids" 0 High P01837 Immunoglobulin kappa constant OS=Mus musculus OX=10090 GN=Igkc PE=1 SV=2 0 245.604 95 12 488 12 107 11.9 5.9 11 11 12 9 171 98 138 81 3694712679 2687298905 3670485879 1956619822 22 21 22 20 0 High P19096 Fatty acid synthase OS=Mus musculus OX=10090 GN=Fasn PE=1 SV=2 0 720.765 61 114 486 114 2504 272.3 6.58 84 21 77 99 150 23 121 192 650984551.7 157049439.8 1037239071 2174720147 108 47 97 104 Acetyl [N-Term] cell differentiation;metabolic process;response to stimulus cytoplasm;cytosol;Golgi;membrane;mitochondrion catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00106, Pf00107, Pf00109, Pf00550, Pf00698, Pf00975, Pf02801, Pf08241, Pf08242, Pf08659, Pf12847, Pf13489, Pf13602, Pf13847, Pf14765" 14104 ENSMUSG00000025153.9 Fasn 11 ChREBP activates metabolic gene expression; Fatty acyl-CoA biosynthesis; Vitamin B5 (pantothenate) metabolism Fatty acid metabolism; Insulin signaling pathway; Metabolic pathways; AMPK signaling pathway; Fatty acid biosynthesis 0 High Q99KI0 "Aconitate hydratase, mitochondrial OS=Mus musculus OX=10090 GN=Aco2 PE=1 SV=1" 0 475.225 62 47 483 47 780 85.4 7.93 41 46 41 41 124 142 101 116 1071109215 2635928700 1639783174 2294809223 51 52 50 47 metabolic process;response to stimulus mitochondrion catalytic activity;metal ion binding "Pf00330, Pf00694" 11429 ENSMUSG00000022477.12 Aco2 15 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Biosynthesis of amino acids; 2-Oxocarboxylic acid metabolism; Carbon metabolism; Glyoxylate and dicarboxylate metabolism 0 High Q99JY0 "Trifunctional enzyme subunit beta, mitochondrial OS=Mus musculus OX=10090 GN=Hadhb PE=1 SV=1" 0 389.958 71 34 483 34 475 51.4 9.38 34 29 31 33 152 86 97 148 1706130675 1409627557 1435772828 2950005245 43 38 39 42 metabolic process endoplasmic reticulum;membrane;mitochondrion catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00108, Pf00109, Pf02803" 231086 ENSMUSG00000059447.13 Hadhb 5 Beta oxidation of myristoyl-CoA to lauroyl-CoA; Acyl chain remodeling of CL; Beta oxidation of palmitoyl-CoA to myristoyl-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA "Fatty acid metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Fatty acid degradation; Fatty acid elongation" 0 High Q9WUB3 "Glycogen phosphorylase, muscle form OS=Mus musculus OX=10090 GN=Pygm PE=1 SV=3" 0 429.343 76 70 440 56 842 97.2 7.11 66 52 47 54 156 89 85 110 3154995625 1198351073 734457500.1 1116650663 73 64 62 60 Met-loss+Acetyl [N-Term] cellular homeostasis;metabolic process;response to stimulus cytoplasm;endoplasmic reticulum catalytic activity;nucleotide binding Pf00343 19309 ENSMUSG00000032648.14; ENSMUSG00000106877.3 Pygm 19; CHR_MG4249_PATCH Glycogen breakdown (glycogenolysis) Insulin signaling pathway; Metabolic pathways; Insulin resistance; Starch and sucrose metabolism; Glucagon signaling pathway 18 High Q9DCL9 Multifunctional protein ADE2 OS=Mus musculus OX=10090 GN=Paics PE=1 SV=4 0 405.732 89 43 436 43 425 47 7.23 1 38 41 41 1 113 168 154 2865223.617 3460410757 5973226600 5224018886 7 46 48 47 Met-loss+Acetyl [N-Term] metabolic process cytoplasm;membrane catalytic activity;nucleotide binding;protein binding "Pf00731, Pf01259" 67054 ENSMUSG00000029247.17 Paics 5 Purine ribonucleoside monophosphate biosynthesis Metabolic pathways; Purine metabolism 0 High Q8VEH8 Endoplasmic reticulum lectin 1 OS=Mus musculus OX=10090 GN=Erlec1 PE=1 SV=1 0 561.735 86 40 419 40 483 54.9 6.25 19 31 40 38 115 266 44439149.1 423701947.9 2536847648 8311433113 6 28 42 50 metabolic process;transport endoplasmic reticulum;organelle lumen protein binding "Pf07915, Pf13015" 66753 ENSMUSG00000020311.17 Erlec1 11 Hedgehog ligand biogenesis; ABC-family proteins mediated transport Protein processing in endoplasmic reticulum 0 High Q91ZA3 "Propionyl-CoA carboxylase alpha chain, mitochondrial OS=Mus musculus OX=10090 GN=Pcca PE=1 SV=2" 0 507.897 72 53 403 53 724 79.9 7.25 6 41 46 51 6 72 142 183 23798307.53 839102606.2 2502157838 3914623961 19 47 55 55 extracellular;mitochondrion;organelle lumen catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00289, Pf00364, Pf01071, Pf02222, Pf02258, Pf02785, Pf02786, Pf07478, Pf08442, Pf13533, Pf13535, Pf13549, Pf15632" 110821 ENSMUSG00000041650.15 Pcca 14 Propionyl-CoA catabolism; Biotin transport and metabolism "Valine, leucine and isoleucine degradation; Metabolic pathways; Propanoate metabolism; Carbon metabolism; Glyoxylate and dicarboxylate metabolism" 0 High Q9ET01 "Glycogen phosphorylase, liver form OS=Mus musculus OX=10090 GN=Pygl PE=1 SV=4" 0 433.899 74 66 372 57 850 97.4 7.09 65 30 36 44 212 45 51 64 966028382.7 233936728.3 250406275.2 362224490.6 63 41 35 37 Met-loss+Acetyl [N-Term] cell death;metabolic process cytoplasm catalytic activity;nucleotide binding;protein binding Pf00343 110095 ENSMUSG00000021069.16 Pygl 12 Glycogen breakdown (glycogenolysis); Neutrophil degranulation Insulin signaling pathway; Metabolic pathways; Insulin resistance; Starch and sucrose metabolism; Glucagon signaling pathway 0 High Q60597 "2-oxoglutarate dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Ogdh PE=1 SV=3" 0 416.126 60 63 329 63 1023 116.4 6.83 57 39 46 43 119 65 76 69 802551589.5 619973125.7 781733316.8 928589241.3 69 58 61 60 cellular component movement;metabolic process cytosol;membrane;mitochondrion;organelle lumen catalytic activity;metal ion binding;protein binding "Pf00676, Pf02779" 18293 ENSMUSG00000020456.17 Ogdh 11 Lysine catabolism; Citric acid cycle (TCA cycle); Glyoxylate metabolism and glycine degradation Tryptophan metabolism; Citrate cycle (TCA cycle); Metabolic pathways; Lysine degradation; Carbon metabolism 0 High A0A0A6YVP0 Immunoglobulin heavy constant gamma 2B (Fragment) OS=Mus musculus OX=10090 GN=Ighg2b PE=1 SV=2 0 212.628 41 15 323 14 405 44.3 6.52 15 15 13 12 117 69 84 53 1136641615 623173828 1045120735 496911191.8 20 18 17 12 membrane "Pf07654, Pf08205" 3 High P00687 Alpha-amylase 1 OS=Mus musculus OX=10090 GN=Amy1 PE=1 SV=2 0 416.496 85 34 309 22 511 57.6 6.96 34 23 7 30 185 41 9 74 2212908107 532995732.6 162245233 1326578553 54 30 14 39 metabolic process extracellular catalytic activity;metal ion binding "Pf00128, Pf02806" 11722 ENSMUSG00000074264.12 Amy1 3 Digestion of dietary carbohydrate Carbohydrate digestion and absorption; Metabolic pathways; Starch and sucrose metabolism 17 High Q8BWT1 "3-ketoacyl-CoA thiolase, mitochondrial OS=Mus musculus OX=10090 GN=Acaa2 PE=1 SV=3" 0 413.366 83 31 306 31 397 41.8 8.09 27 27 25 30 65 53 60 128 569828478.4 652227931 827954929.3 3618013885 33 31 28 34 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion;organelle lumen catalytic activity;RNA binding "Pf00108, Pf02801, Pf02803" 52538 ENSMUSG00000036880.9 Acaa2 18 Mitochondrial Fatty Acid Beta-Oxidation "Fatty acid metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Fatty acid degradation; Fatty acid elongation" 0 High P38647 "Stress-70 protein, mitochondrial OS=Mus musculus OX=10090 GN=Hspa9 PE=1 SV=3" 0 324.411 58 45 303 44 679 73.4 6.07 40 39 38 42 95 61 60 87 1032169828 1095715839 957548638.4 1725908486 45 44 44 45 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;mitochondrion;nucleus;organelle lumen nucleotide binding;protein binding;RNA binding "Pf00012, Pf06723" 15526 ENSMUSG00000024359.8 Hspa9 18 RNA degradation; Tuberculosis 1 High P50544 "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Acadvl PE=1 SV=3" 0 343.175 79 45 287 45 656 70.8 8.75 34 33 35 43 61 56 69 101 236022952.8 402442807.1 616403276.9 1246593613 42 40 43 43 cell differentiation;metabolic process;regulation of biological process;response to stimulus cytosol;membrane;mitochondrion;nucleus catalytic activity;nucleotide binding "Pf00441, Pf02770, Pf02771, Pf08028" 11370 ENSMUSG00000018574.14 Acadvl 11 Beta oxidation of palmitoyl-CoA to myristoyl-CoA Fatty acid metabolism; Metabolic pathways; Fatty acid degradation 0 High Q99MN9 "Propionyl-CoA carboxylase beta chain, mitochondrial OS=Mus musculus OX=10090 GN=Pccb PE=1 SV=2" 0 330.726 83 37 263 37 541 58.4 7.66 4 27 34 36 5 57 94 107 36382472.19 628924423.9 1960825401 2726666137 16 35 37 38 metabolic process mitochondrion;organelle lumen catalytic activity;nucleotide binding Pf01039 66904 ENSMUSG00000032527.13 Pccb 9 Propionyl-CoA catabolism; Biotin transport and metabolism "Valine, leucine and isoleucine degradation; Metabolic pathways; Propanoate metabolism; Carbon metabolism; Glyoxylate and dicarboxylate metabolism" 0 High Q569Z6 Thyroid hormone receptor-associated protein 3 OS=Mus musculus OX=10090 GN=Thrap3 PE=1 SV=1 0 224.53 43 43 214 42 951 108.1 10.17 30 39 31 58 90 66 21804966.27 792170379.8 1338445357 1042001826 8 39 40 39 metabolic process;regulation of biological process;response to stimulus nucleus DNA binding;nucleotide binding;protein binding;receptor activity;RNA binding Pf15440 230753 ENSMUSG00000043962.16 Thrap3 4 Mus musculus biological processes; Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes 1 High Q60847 Collagen alpha-1(XII) chain OS=Mus musculus OX=10090 GN=Col12a1 PE=2 SV=3 0 235.197 21 56 205 56 3120 340 5.64 47 33 30 30 83 43 44 35 338219426.6 281419306.2 298158782.1 318292930.2 50 42 43 40 cell differentiation extracellular protein binding "Pf00041, Pf00092, Pf13519" 12816 Col12a1 9 Collagen chain trimerization; Collagen degradation; Assembly of collagen fibrils and other multimeric structures Protein digestion and absorption 0 High Q924X2 "Carnitine O-palmitoyltransferase 1, muscle isoform OS=Mus musculus OX=10090 GN=Cpt1b PE=1 SV=1" 0 221.436 57 38 204 38 772 88.2 8.38 20 15 24 38 35 20 41 108 95651932.09 158385831.3 325243217.4 2153170960 30 26 31 38 Met-loss+Acetyl [N-Term] metabolic process;transport membrane;mitochondrion catalytic activity Pf00755 12895 ENSMUSG00000078937.8 Cpt1b 15 Signaling by Retinoic Acid; Import of palmitoyl-CoA into the mitochondrial matrix PPAR signaling pathway; Fatty acid metabolism; Fatty acid degradation; Insulin resistance; Adipocytokine signaling pathway; AMPK signaling pathway; Glucagon signaling pathway 0 High Q8R4U7 Leucine zipper protein 1 OS=Mus musculus OX=10090 GN=Luzp1 PE=1 SV=2 0 308.039 67 62 201 62 1068 119.2 7.99 41 46 48 59 72 70 18614055.81 401210361.5 534406367.8 564092045.8 8 51 52 51 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process membrane;nucleus catalytic activity "Pf04111, Pf04799" 269593 ENSMUSG00000001089.14 Luzp1 4 0 High A0A075B5P6 Immunoglobulin heavy constant mu (Fragment) OS=Mus musculus OX=10090 GN=Ighm PE=1 SV=1 0 144.847 43 23 196 23 455 50 7.01 21 19 19 16 78 40 47 31 1124901363 590592591.5 770974914 531898448.5 28 22 22 20 "Pf07654, Pf07679" ENSMUSG00000076617.9 12 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Cell surface interactions at the vascular wall; CD22 mediated BCR regulation 0 High A0A1Y7VJN6 Immunoglobulin heavy constant gamma 3 (Fragment) OS=Mus musculus OX=10090 GN=Ighg3 PE=4 SV=1 0 122.792 53 17 193 17 399 44 7.14 16 9 13 12 80 27 56 30 696730061 242856708.7 606762944.3 308505230 19 14 16 15 membrane "Pf07654, Pf08205" 0 High Q3U7K7 E3 ubiquitin-protein ligase TRIM21 OS=Mus musculus OX=10090 GN=Trim21 PE=1 SV=1 0 170.586 55 31 184 31 462 53.3 6.7 25 23 25 24 59 40 49 36 396217419.3 527599770.1 631183980.4 651656543.6 29 29 28 27 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus catalytic activity;DNA binding;metal ion binding;protein binding;RNA binding "Pf00097, Pf00622, Pf00643, Pf13445, Pf13639, Pf13765, Pf13920, Pf13923, Pf14634, Pf14835, Pf15227" 20821 ENSMUSG00000030966.13 Trim21 7 Antigen processing: Ubiquitination & Proteasome degradation; Regulation of innate immune responses to cytosolic DNA Systemic lupus erythematosus 0 High Q8CI94 "Glycogen phosphorylase, brain form OS=Mus musculus OX=10090 GN=Pygb PE=1 SV=3" 0 229.679 57 46 184 33 843 96.7 6.73 43 24 13 27 86 33 24 41 3935936166 720341481.1 588680196.4 785583264.1 35 26 20 26 Met-loss+Acetyl [N-Term] metabolic process cytoplasm;membrane catalytic activity;protein binding Pf00343 110078 ENSMUSG00000033059.7 Pygb 2 Neutrophil degranulation Insulin signaling pathway; Metabolic pathways; Insulin resistance; Starch and sucrose metabolism; Glucagon signaling pathway 0 High Q8K2B3 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Mus musculus OX=10090 GN=Sdha PE=1 SV=1" 0 259.771 66 31 179 31 664 72.5 7.37 23 24 21 30 48 40 31 60 193272389.3 302020521.4 267065178.5 631318924.5 28 31 31 31 metabolic process;transport membrane;mitochondrion catalytic activity;nucleotide binding "Pf00890, Pf02910" 66945 ENSMUSG00000021577.13 Sdha 13 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Carbon metabolism 0 High Q8CG16 Complement C1r-A subcomponent OS=Mus musculus OX=10090 GN=C1ra PE=1 SV=1 0 221.04 66 34 173 34 707 80 5.66 30 22 21 19 67 36 45 25 660381212.8 259600607.5 333556533.8 329938587.5 33 25 26 23 defense response;metabolic process;regulation of biological process;response to stimulus catalytic activity;metal ion binding "Pf00084, Pf00089, Pf00431, Pf07645, Pf12662, Pf14670" 50909 ENSMUSG00000055172.10 C1ra 6 Regulation of Complement cascade; Classical antibody-mediated complement activation Staphylococcus aureus infection; Phagosome; Complement and coagulation cascades; Pertussis; Systemic lupus erythematosus 0 High A0A0A6YWR2 Ig gamma-1 chain C region secreted form (Fragment) OS=Mus musculus OX=10090 GN=Ighg1 PE=1 SV=1 0 140.124 43 11 171 3 393 43.4 6.44 11 8 8 9 69 26 41 35 499004889.4 343748603.4 468172373.5 292685850.8 17 12 13 13 membrane "Pf07654, Pf08205" ENSMUSG00000076614.7 12 Regulation of Complement cascade; Role of phospholipids in phagocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR activation; Classical antibody-mediated complement activation 12 High P16858 Glyceraldehyde-3-phosphate dehydrogenase OS=Mus musculus OX=10090 GN=Gapdh PE=1 SV=2 0 237.122 74 21 171 21 333 35.8 8.25 14 13 12 21 28 21 26 96 109149424.9 198834217.4 286607563.4 2149548457 20 16 19 30 Met-loss [N-Term] cell death;cell organization and biogenesis;defense response;development;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;mitochondrion;nucleus catalytic activity;enzyme regulator activity;nucleotide binding;protein binding "Pf00044, Pf02800" 14433; 100042025; 100042746 ENSMUSG00000057666.18 Gapdh; Gm20899; LOC100042025; Gapdh-ps15; Gm12033 6; Y; 11 Metabolic pathways; Biosynthesis of amino acids; Glycolysis / Gluconeogenesis; HIF-1 signaling pathway; Alzheimer's disease; Carbon metabolism 0 High P07724 Albumin OS=Mus musculus OX=10090 GN=Alb PE=1 SV=3 0 175.576 65 32 168 32 608 68.6 6.07 22 30 24 19 44 49 39 36 202490611.1 309324684.4 271504773.6 360958622.9 28 29 29 28 cell communication;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;extracellular;Golgi;nucleus DNA binding;metal ion binding;protein binding Pf00273 11657 ENSMUSG00000029368.10 Alb 5 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Recycling of bile acids and salts; Platelet degranulation ; Transport of organic anions; HDL remodeling; Scavenging of heme from plasma Thyroid hormone synthesis 0 High P01869 "Ig gamma-1 chain C region, membrane-bound form OS=Mus musculus OX=10090 GN=Ighg1 PE=1 SV=2" 0 135.685 32 9 165 1 393 43.4 6.44 9 7 8 7 65 27 42 31 181071479 101574135.3 141865477 38662361 2 2 2 2 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus membrane protein binding "Pf07654, Pf08205" 16017 Ighg1 12 0 High P63017 Heat shock cognate 71 kDa protein OS=Mus musculus OX=10090 GN=Hspa8 PE=1 SV=1 0 183.475 46 30 164 27 646 70.8 5.52 24 15 16 26 44 17 28 75 147088667.4 154961549.3 213974784.3 467175765.6 27 23 25 25 cell organization and biogenesis;metabolic process;regulation of biological process;transport cell surface;cytoplasm;cytosol;endosome;membrane;nucleus;spliceosomal complex;vacuole catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00012, Pf02463, Pf06723" 15481 ENSMUSG00000015656.17 Hspa8 9 "Regulation of HSF1-mediated heat shock response; Golgi Associated Vesicle Biogenesis; mRNA Splicing - Major Pathway; Attenuation phase; Neutrophil degranulation; AUF1 (hnRNP D0) binds and destabilizes mRNA; GABA synthesis, release, reuptake and degradation; HSP90 chaperone cycle for steroid hormone receptors (SHR); Protein methylation; Clathrin-mediated endocytosis" Endocytosis; MAPK signaling pathway; Toxoplasmosis; Epstein-Barr virus infection; Spliceosome; Legionellosis; Influenza A; Antigen processing and presentation; Protein processing in endoplasmic reticulum; Estrogen signaling pathway; Measles; Longevity regulating pathway - multiple species 0 High Q91VA7 "Isocitrate dehydrogenase [NAD] subunit, mitochondrial OS=Mus musculus OX=10090 GN=Idh3b PE=1 SV=1" 0 200.524 60 28 161 28 384 42.2 8.6 19 16 14 27 35 25 23 78 187487010.5 266956987.9 218274421.3 1209327200 24 22 22 27 metabolic process mitochondrion;nucleus catalytic activity;metal ion binding;nucleotide binding Pf00180 170718 ENSMUSG00000027406.12 Idh3b 2 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Biosynthesis of amino acids; 2-Oxocarboxylic acid metabolism; Carbon metabolism 0 High O88569 Heterogeneous nuclear ribonucleoproteins A2/B1 OS=Mus musculus OX=10090 GN=Hnrnpa2b1 PE=1 SV=2 0 215.893 74 27 159 24 353 37.4 8.95 23 24 22 22 46 46 31 36 314948790.5 583134657.5 406467461.5 527006569.8 29 28 27 26 cell organization and biogenesis;metabolic process;regulation of biological process;transport chromosome;cytoplasm;extracellular;membrane;nucleus;spliceosomal complex DNA binding;protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 53379 ENSMUSG00000004980.16 Hnrnpa2b1 6 mRNA Splicing - Major Pathway 3 High G5E8R3 Pyruvate carboxylase OS=Mus musculus OX=10090 GN=Pcx PE=1 SV=1 0 230.733 54 49 159 49 1178 129.6 6.71 36 18 24 36 62 21 29 47 237496775.9 133661418.2 181447111 404774879.8 44 33 36 43 metabolic process;regulation of biological process cytoplasm;membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00289, Pf00364, Pf00682, Pf02222, Pf02436, Pf02785, Pf02786, Pf07478, Pf08443, Pf13533, Pf13535, Pf15632" 18563 ENSMUSG00000024892.15 Pcx 19 Biotin transport and metabolism; Gluconeogenesis 0 High Q3UHU8 General transcription factor II-I OS=Mus musculus OX=10090 GN=Gtf2i PE=1 SV=1 0 209.454 54 48 157 48 962 108.3 7.8 40 24 20 20 76 30 24 27 195455989.9 211097450.9 171112300.9 220395982.6 44 38 34 33 cellular homeostasis;metabolic process;regulation of biological process cytoplasm;membrane;nucleus DNA binding;protein binding Pf02946 14886 ENSMUSG00000060261.15 Gtf2i 5 0 High Q9Z2I9 "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial OS=Mus musculus OX=10090 GN=Sucla2 PE=1 SV=2" 0 158.474 59 27 155 27 463 50.1 7.01 18 20 19 27 28 31 28 68 149695060.9 271483337.1 361588706.8 2100529385 23 25 25 26 metabolic process mitochondrion catalytic activity;metal ion binding;nucleotide binding "Pf00549, Pf02222, Pf02786, Pf08442, Pf13535, Pf13549" 20916 ENSMUSG00000022110.13 Sucla2 14 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Propanoate metabolism; Carbon metabolism 0 High P20152 Vimentin OS=Mus musculus OX=10090 GN=Vim PE=1 SV=3 0 161.95 70 36 152 33 466 53.7 5.12 30 20 21 27 57 24 33 38 349044815.5 214264873.9 265342984.6 431201122.3 35 27 29 29 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane protein binding;RNA binding;structural molecule activity "Pf00038, Pf04111, Pf04156, Pf04732, Pf05622, Pf10186" 22352 ENSMUSG00000026728.9 Vim 2 Striated Muscle Contraction; Caspase-mediated cleavage of cytoskeletal proteins MicroRNAs in cancer; Epstein-Barr virus infection 3 High Q8BMF4 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Mus musculus OX=10090 GN=Dlat PE=1 SV=2" 0 137.357 42 22 140 22 642 67.9 8.57 21 15 15 13 63 22 32 23 539411820.6 203239685.8 344633889.5 244117465.5 25 19 19 17 metabolic process mitochondrion;organelle lumen catalytic activity;protein binding "Pf00198, Pf00364, Pf02817" 235339 ENSMUSG00000000168.9 Dlat 9 Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Glyoxylate metabolism and glycine degradation Pyruvate metabolism; Citrate cycle (TCA cycle); Metabolic pathways; Glycolysis / Gluconeogenesis; Carbon metabolism 0 High Q8CG14 Complement C1s-A subcomponent OS=Mus musculus OX=10090 GN=C1sa PE=2 SV=2 0 176.059 56 31 140 18 688 76.8 5.08 29 19 19 14 60 29 31 20 401473575.1 231595405 286487845.1 194054476.8 31 25 26 20 defense response;metabolic process;regulation of biological process;response to stimulus extracellular catalytic activity;metal ion binding;protein binding "Pf00084, Pf00089, Pf00431, Pf07645, Pf14670" 50908 C1s; C1s1 6 Staphylococcus aureus infection; Complement and coagulation cascades; Pertussis; Systemic lupus erythematosus 13 High P15105 Glutamine synthetase OS=Mus musculus OX=10090 GN=Glul PE=1 SV=6 0 151.474 63 23 138 23 373 42.1 7.08 16 14 19 19 40 23 41 34 393972433.8 306559549.8 871316663.9 515915275.1 22 19 22 22 Met-loss+Acetyl [N-Term] cell communication;cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;endoplasmic reticulum;mitochondrion;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00120, Pf03951" 14645 ENSMUSG00000026473.15 Glul 1 Astrocytic Glutamate-Glutamine Uptake And Metabolism; Amino acid synthesis and interconversion (transamination) "GABAergic synapse; Metabolic pathways; Nitrogen metabolism; Biosynthesis of amino acids; Glutamatergic synapse; Alanine, aspartate and glutamate metabolism; Arginine biosynthesis; Glyoxylate and dicarboxylate metabolism" 0 High P21981 Protein-glutamine gamma-glutamyltransferase 2 OS=Mus musculus OX=10090 GN=Tgm2 PE=1 SV=4 0 180.381 58 33 132 33 686 77 5.1 31 18 25 14 58 24 33 17 436076919.8 243243845.4 251632197.5 138483130.4 30 25 25 20 Met-loss+Acetyl [N-Term] cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;endoplasmic reticulum;membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00868, Pf00927, Pf01841" 21817 ENSMUSG00000037820.15 Tgm2 2 Huntington's disease 0 High Q3ULD5 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Mus musculus OX=10090 GN=Mccc2 PE=1 SV=1" 0 179.322 73 28 130 28 563 61.3 8 21 17 21 21 37 23 33 37 104973508.2 152592414.5 231846893.7 313995341.6 24 25 24 23 metabolic process mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf01039, Pf03255" 78038 ENSMUSG00000021646.8 Mccc2 13 Biotin transport and metabolism; Branched-chain amino acid catabolism "Valine, leucine and isoleucine degradation; Metabolic pathways" 0 High P12242 Mitochondrial brown fat uncoupling protein 1 OS=Mus musculus OX=10090 GN=Ucp1 PE=1 SV=2 0 172.853 84 21 129 21 307 33.2 9.14 8 15 14 21 10 21 21 77 45015557.44 169866593.8 253494021.7 2132737004 13 17 15 21 Met-loss [N-Term] cell differentiation;regulation of biological process;response to stimulus;transport membrane;mitochondrion nucleotide binding;protein binding;transporter activity Pf00153 22227 ENSMUSG00000031710.4 Ucp1 8 The proton buffering model; The fatty acid cycling model PPAR signaling pathway; Huntington's disease 0 High Q8K010 5-oxoprolinase OS=Mus musculus OX=10090 GN=Oplah PE=1 SV=1 0 238.94 34 37 127 37 1288 137.5 6.28 29 14 18 32 44 15 19 49 88074589.06 105113347.8 136696731.3 307106366 34 30 31 32 metabolic process cytosol catalytic activity;nucleotide binding "Pf01968, Pf02538, Pf05378" 75475 ENSMUSG00000022562.14 Oplah 15 Glutathione synthesis and recycling Glutathione metabolism 0 High Q9WUM5 "Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial OS=Mus musculus OX=10090 GN=Suclg1 PE=1 SV=4" 0 139.081 54 17 126 17 346 36.1 9.39 12 13 14 16 34 21 25 46 201773808.2 240050148.7 341444844.7 1017196588 16 14 17 18 metabolic process cytosol;membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00549, Pf02629, Pf13607" 56451 ENSMUSG00000052738.14 Suclg1 6 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Propanoate metabolism; Carbon metabolism 0 High P53395 "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial OS=Mus musculus OX=10090 GN=Dbt PE=1 SV=2" 0 105.934 55 23 126 23 482 53.2 8.6 22 15 12 13 61 23 19 23 270554303.6 139906618.6 171267727.9 161532489.6 22 18 16 18 metabolic process mitochondrion;organelle lumen catalytic activity;protein binding "Pf00198, Pf00364, Pf02817" 13171 ENSMUSG00000000340.10 Dbt 3 Glyoxylate metabolism and glycine degradation; Branched-chain amino acid catabolism "Valine, leucine and isoleucine degradation; Metabolic pathways; Propanoate metabolism" 0 High P14106 Complement C1q subcomponent subunit B OS=Mus musculus OX=10090 GN=C1qb PE=1 SV=2 0 64.44 47 9 125 9 253 26.7 8.15 8 7 7 7 52 21 29 23 1034949290 594311510 808013045.1 607083946.1 12 10 10 9 defense response;metabolic process;regulation of biological process;response to stimulus extracellular;membrane protein binding "Pf00229, Pf00386" 12260 ENSMUSG00000036905.8 C1qb 4 Regulation of Complement cascade; Classical antibody-mediated complement activation Chagas disease (American trypanosomiasis); Staphylococcus aureus infection; Complement and coagulation cascades; Pertussis; Prion diseases; Systemic lupus erythematosus 0 High Q99MR8 "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial OS=Mus musculus OX=10090 GN=Mccc1 PE=1 SV=2" 0 170.606 51 31 125 30 717 79.3 7.83 18 17 21 23 28 22 34 41 96151477.38 151391318.8 272497064.6 394471486.4 25 25 26 27 metabolic process membrane;mitochondrion;organelle lumen catalytic activity;metal ion binding;nucleotide binding "Pf00289, Pf00364, Pf01071, Pf02222, Pf02785, Pf02786, Pf07478, Pf13533, Pf13535, Pf15632" 72039 ENSMUSG00000027709.9 Mccc1 3 Biotin transport and metabolism; Branched-chain amino acid catabolism "Valine, leucine and isoleucine degradation; Metabolic pathways" 0 High E9Q3L2 Phosphatidylinositol 4-kinase alpha OS=Mus musculus OX=10090 GN=Pi4ka PE=1 SV=2 0 200.887 29 48 124 48 2105 236.9 7.06 30 30 34 40 39 45 3791771.688 165363665.5 189962975.9 322193518.2 3 35 34 36 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane catalytic activity;nucleotide binding;protein binding "Pf00454, Pf00613" 224020 Pi4ka 16 Metabolic pathways; Inositol phosphate metabolism; Phosphatidylinositol signaling system 0 High Q8VCM7 Fibrinogen gamma chain OS=Mus musculus OX=10090 GN=Fgg PE=1 SV=1 0 152.396 59 22 123 22 436 49.4 5.86 20 13 15 15 51 20 28 24 191802421.2 117113551.1 193970211.3 132514161.5 21 19 21 17 cell organization and biogenesis;coagulation;defense response;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;extracellular metal ion binding;protein binding;structural molecule activity "Pf00147, Pf08702" 99571 ENSMUSG00000033860.13 Fgg 3 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); p130Cas linkage to MAPK signaling for integrins; Post-translational protein phosphorylation; Integrin cell surface interactions; Regulation of TLR by endogenous ligand; Common Pathway of Fibrin Clot Formation; GRB2:SOS provides linkage to MAPK signaling for Integrins ; Platelet degranulation Staphylococcus aureus infection; Platelet activation; Complement and coagulation cascades 0 High P70404 "Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial OS=Mus musculus OX=10090 GN=Idh3g PE=1 SV=1" 0 178.43 48 14 121 14 393 42.8 9.01 12 13 13 14 36 21 25 39 216658045.5 182345497.5 222792519.3 485239593 13 12 14 14 metabolic process;regulation of biological process mitochondrion catalytic activity;metal ion binding;nucleotide binding Pf00180 15929 ENSMUSG00000002010.17 Idh3g X Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Biosynthesis of amino acids; 2-Oxocarboxylic acid metabolism; Carbon metabolism 0 High P11276 Fibronectin OS=Mus musculus OX=10090 GN=Fn1 PE=1 SV=4 0 219.478 23 43 120 43 2477 272.4 5.59 43 17 15 4 75 21 20 4 249878215.9 126212871.8 150596924.1 43773723.88 42 26 28 10 cell differentiation;cell organization and biogenesis;cellular component movement;defense response;metabolic process;regulation of biological process;response to stimulus extracellular;membrane enzyme regulator activity;metal ion binding;protein binding "Pf00039, Pf00040, Pf00041" 14268 ENSMUSG00000026193.15 Fn1 1 ECM proteoglycans; Molecules associated with elastic fibres; Degradation of the extracellular matrix; Cell surface interactions at the vascular wall; Post-translational protein phosphorylation; Integrin cell surface interactions; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); p130Cas linkage to MAPK signaling for integrins; MET activates PTK2 signaling; GRB2:SOS provides linkage to MAPK signaling for Integrins ; Platelet degranulation ; Syndecan interactions; Fibronectin matrix formation AGE-RAGE signaling pathway in diabetic complications; Regulation of actin cytoskeleton; Focal adhesion; Small cell lung cancer; Proteoglycans in cancer; Pathways in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway; Amoebiasis; Bacterial invasion of epithelial cells 0 High Q03265 "ATP synthase subunit alpha, mitochondrial OS=Mus musculus OX=10090 GN=Atp5f1a PE=1 SV=1" 0 170.934 55 29 120 29 553 59.7 9.19 9 12 17 29 14 15 25 66 45252625.47 149777119.4 211502135.1 1029768474 17 21 23 29 metabolic process;regulation of biological process;transport membrane;mitochondrion catalytic activity;nucleotide binding;protein binding;RNA binding;transporter activity "Pf00006, Pf00306, Pf02663, Pf02874, Pf05943" 11946 ENSMUSG00000025428.15 Atp5a1 18 Cristae formation; Formation of ATP by chemiosmotic coupling Metabolic pathways; Huntington's disease; Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High P51881 ADP/ATP translocase 2 OS=Mus musculus OX=10090 GN=Slc25a5 PE=1 SV=3 0 76.778 67 18 118 9 298 32.9 9.73 9 13 12 18 17 21 21 59 18891277.94 64715350 64489806.5 868017935.9 5 6 6 9 Met-loss+Acetyl [N-Term] cell organization and biogenesis;regulation of biological process;transport membrane;mitochondrion;nucleus protein binding;RNA binding;transporter activity Pf00153 11740 ENSMUSG00000016319.3 Slc25a5 X Regulation of insulin secretion HTLV-I infection; Huntington's disease; Parkinson's disease; cGMP-PKG signaling pathway; Calcium signaling pathway 0 High P60710 "Actin, cytoplasmic 1 OS=Mus musculus OX=10090 GN=Actb PE=1 SV=1" 0 119.912 63 17 116 8 375 41.7 5.48 16 12 13 15 32 24 22 38 158126949.7 194590634.1 241754653 687208022.3 18 17 17 18 Met-loss+Acetyl [N-Term] cell organization and biogenesis;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;nucleus DNA binding;nucleotide binding;protein binding Pf00022 11461 ENSMUSG00000029580.14 Actb 5 Interaction between L1 and Ankyrins; DNA Damage Recognition in GG-NER; VEGFA-VEGFR2 Pathway; Adherens junctions interactions; UCH proteinases; Regulation of actin dynamics for phagocytic cup formation; B-WICH complex positively regulates rRNA expression; RHO GTPases activate IQGAPs; Formation of annular gap junctions; RHO GTPases Activate Formins; Recycling pathway of L1; RHO GTPases Activate WASPs and WAVEs; Cell-extracellular matrix interactions; Clathrin-mediated endocytosis; EPHB-mediated forward signaling Oxytocin signaling pathway; Leukocyte transendothelial migration; Hypertrophic cardiomyopathy (HCM); Regulation of actin cytoskeleton; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Focal adhesion; Hippo signaling pathway; Platelet activation; Dilated cardiomyopathy; Adherens junction; Phagosome; Proteoglycans in cancer; Salmonella infection; Thyroid hormone signaling pathway; Rap1 signaling pathway; Influenza A; Viral myocarditis; Tight junction; Gastric acid secretion; Bacterial invasion of epithelial cells; Apoptosis 11 High Q8K0E8 Fibrinogen beta chain OS=Mus musculus OX=10090 GN=Fgb PE=1 SV=1 0 149.02 61 23 116 23 481 54.7 7.08 18 14 15 14 38 20 33 25 191049723.9 117592038.9 220778634.4 179446643.3 22 20 23 18 cell organization and biogenesis;coagulation;defense response;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;extracellular protein binding;structural molecule activity "Pf00147, Pf01920, Pf08702" 110135 ENSMUSG00000033831.5 Fgb 3 p130Cas linkage to MAPK signaling for integrins; Integrin cell surface interactions; Regulation of TLR by endogenous ligand; Common Pathway of Fibrin Clot Formation; GRB2:SOS provides linkage to MAPK signaling for Integrins ; Platelet degranulation Platelet activation; Complement and coagulation cascades 0 High P00688 Pancreatic alpha-amylase OS=Mus musculus OX=10090 GN=Amy2 PE=1 SV=2 0 141.201 57 23 115 11 508 57.3 7.28 22 8 3 14 67 14 4 30 43318439.13 13480003.38 3317263.25 68889521.75 11 5 2 11 metabolic process extracellular catalytic activity;metal ion binding "Pf00128, Pf02806" 109959; 100043688; 100043686; 100043684 ENSMUSG00000074268.4; ENSMUSG00000096770.2; ENSMUSG00000093931.2; ENSMUSG00000096569.2 Amy2a5; Amy2a2; Amy2a3; Amy2a4 3 Digestion of dietary carbohydrate Pancreatic secretion; Carbohydrate digestion and absorption; Metabolic pathways; Starch and sucrose metabolism 0 High Q02105 Complement C1q subcomponent subunit C OS=Mus musculus OX=10090 GN=C1qc PE=1 SV=2 0 71.598 31 7 113 7 246 26 8.54 7 6 6 5 48 24 25 16 699737768.2 397636638.3 473047274.4 404172434.8 11 9 10 9 defense response;metabolic process;regulation of biological process;response to stimulus extracellular;membrane protein binding "Pf00229, Pf00386, Pf01391" 12262 ENSMUSG00000036896.5 C1qc 4 Regulation of Complement cascade; Classical antibody-mediated complement activation Chagas disease (American trypanosomiasis); Staphylococcus aureus infection; Complement and coagulation cascades; Pertussis; Prion diseases; Systemic lupus erythematosus 0 High A0A0R4J083 "Long-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Acadl PE=1 SV=1" 0 107.956 50 22 108 22 430 47.9 8.15 19 15 15 12 39 26 24 19 155723390.8 199022984.6 176546876.7 160833050.3 22 20 21 19 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf00441, Pf02770, Pf02771, Pf08028" 11363 ENSMUSG00000026003.5 Acadl 1 Beta oxidation of myristoyl-CoA to lauroyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA PPAR signaling pathway; Fatty acid metabolism; Metabolic pathways; Fatty acid degradation 0 High Q8CAQ8 MICOS complex subunit Mic60 OS=Mus musculus OX=10090 GN=Immt PE=1 SV=1 0 181.414 50 40 106 11 757 83.8 6.61 21 7 8 37 31 8 10 57 108384080.7 63091081.13 93237511.88 587944686 30 18 20 36 cell organization and biogenesis;cellular homeostasis membrane;mitochondrion protein binding;RNA binding Pf09731 76614 ENSMUSG00000052337.15 Immt 6 28 High Q8BH95 "Enoyl-CoA hydratase, mitochondrial OS=Mus musculus OX=10090 GN=Echs1 PE=1 SV=1" 0 86.931 55 14 102 14 290 31.5 8.48 12 11 11 11 31 25 20 26 231207776.9 196836710 260647934 481149591.8 15 12 14 13 metabolic process mitochondrion;organelle lumen catalytic activity Pf00378 93747 ENSMUSG00000025465.13 Echs1 7 Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA "Fatty acid metabolism; Tryptophan metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Lysine degradation; Fatty acid degradation; Butanoate metabolism; beta-Alanine metabolism; Propanoate metabolism; Fatty acid elongation; Carbon metabolism" 0 High Q8CGN5 Perilipin-1 OS=Mus musculus OX=10090 GN=Plin1 PE=1 SV=2 0 138.658 64 26 101 26 517 55.6 7.01 11 9 15 26 16 11 19 55 62089747.16 118310910.4 123482367.5 444739371.8 17 19 19 22 metabolic process cytosol;endoplasmic reticulum protein binding Pf03036 103968 ENSMUSG00000030546.14 Plin1 7 PPAR signaling pathway; Regulation of lipolysis in adipocytes 0 High D3Z041 Long-chain-fatty-acid--CoA ligase 1 OS=Mus musculus OX=10090 GN=Acsl1 PE=1 SV=1 0 184.846 60 36 99 33 699 78 7.47 12 6 4 36 15 6 4 74 48333871.28 73691456.63 85840791 893240408.1 26 14 20 38 Acetyl [N-Term] metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion catalytic activity Pf00501 ENSMUSG00000018796.13 8 3 High E9PV24 Fibrinogen alpha chain OS=Mus musculus OX=10090 GN=Fga PE=1 SV=1 0 93.84 30 21 99 21 789 87.4 6.11 18 13 15 15 36 16 25 22 152892599.7 104852753.1 171149236.7 151136291.8 19 15 20 16 cell organization and biogenesis;coagulation;defense response;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;endoplasmic reticulum;extracellular metal ion binding;protein binding;structural molecule activity "Pf00147, Pf08702, Pf12160" 14161 ENSMUSG00000028001.16 Fga 3 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); p130Cas linkage to MAPK signaling for integrins; Post-translational protein phosphorylation; Integrin cell surface interactions; Regulation of TLR by endogenous ligand; Common Pathway of Fibrin Clot Formation; GRB2:SOS provides linkage to MAPK signaling for Integrins ; Platelet degranulation Platelet activation; Complement and coagulation cascades 0 High P35486 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Mus musculus OX=10090 GN=Pdha1 PE=1 SV=1" 0 102.021 58 23 98 23 390 43.2 8.19 21 12 13 18 40 14 15 29 178492068.3 126461036.4 165885009.9 371072093.5 24 17 19 20 metabolic process mitochondrion;nucleus;organelle lumen catalytic activity Pf00676 18597 ENSMUSG00000031299.10 Pdha1 X Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Glyoxylate metabolism and glycine degradation Pyruvate metabolism; Citrate cycle (TCA cycle); Metabolic pathways; Glycolysis / Gluconeogenesis; HIF-1 signaling pathway; Carbon metabolism; Central carbon metabolism in cancer; Glucagon signaling pathway 0 High P01029 Complement C4-B OS=Mus musculus OX=10090 GN=C4b PE=1 SV=3 0 180.362 26 32 97 32 1738 192.8 7.53 28 15 20 10 43 18 26 10 140741648.9 117403013.1 158166716.3 92580677.25 33 24 25 16 defense response;metabolic process;regulation of biological process;response to stimulus extracellular enzyme regulator activity;protein binding "Pf00207, Pf01759, Pf01821, Pf01835, Pf07677, Pf07678, Pf07703, Pf10569, Pf11974, Pf13249" 12268 ENSMUSG00000073418.4 C4b 17 Regulation of Complement cascade; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Activation of C3 and C5; Post-translational protein phosphorylation; Initial triggering of complement Staphylococcus aureus infection; Complement and coagulation cascades; Pertussis; Systemic lupus erythematosus 0 High P19324 Serpin H1 OS=Mus musculus OX=10090 GN=Serpinh1 PE=1 SV=3 0 166.331 59 20 95 20 417 46.5 8.82 2 8 15 20 2 10 26 57 4209093.375 73924415.91 186692154.9 868102510.3 7 14 15 19 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;endoplasmic reticulum;membrane;organelle lumen enzyme regulator activity;protein binding;RNA binding Pf00079 12406 ENSMUSG00000070436.12 Serpinh1 7 Collagen biosynthesis and modifying enzymes 0 High Q3U3J1 2-oxoisovalerate dehydrogenase subunit alpha OS=Mus musculus OX=10090 GN=Bckdha PE=1 SV=1 0 140.046 59 19 95 19 446 50.7 8.06 15 11 10 11 41 18 15 21 250272220.1 104318500.3 115222399 165812284.6 21 15 12 14 metabolic process mitochondrion catalytic activity;metal ion binding;protein binding "Pf00456, Pf00676" 12039 ENSMUSG00000060376.7 Bckdha 7 Glyoxylate metabolism and glycine degradation; Branched-chain amino acid catabolism "Valine, leucine and isoleucine degradation; Metabolic pathways; Propanoate metabolism" 0 High Q91VB8 Alpha globin 1 OS=Mus musculus OX=10090 GN=Hba-a1 PE=1 SV=1 0 97.803 92 10 95 10 142 15.1 8.22 9 10 9 9 31 24 18 22 179980375.7 301002436.8 195086875.6 387487750.3 11 12 12 11 Met-loss [N-Term] response to stimulus;transport membrane antioxidant activity;catalytic activity;metal ion binding;protein binding;transporter activity Pf00042 15122; 110257 ENSMUSG00000069919.7; ENSMUSG00000069917.7 Hba-a1; Hba-a2 11 Erythrocytes take up carbon dioxide and release oxygen; Erythrocytes take up oxygen and release carbon dioxide; Scavenging of heme from plasma African trypanosomiasis; Malaria 0 High Q64521 "Glycerol-3-phosphate dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Gpd2 PE=1 SV=2" 0 137.856 57 32 93 32 727 80.9 6.61 24 11 16 29 28 11 16 38 79878551.41 92235248.63 119012692.6 276988026 29 25 27 29 metabolic process membrane;mitochondrion catalytic activity;metal ion binding "Pf00890, Pf01266, Pf03486, Pf07992, Pf12831, Pf13499" 14571 ENSMUSG00000026827.12 Gpd2 2 Triglyceride catabolism; Synthesis of PA Glycerophospholipid metabolism 0 High E9Q6P5 Tetratricopeptide repeat protein 7B OS=Mus musculus OX=10090 GN=Ttc7b PE=1 SV=1 0 148.23 51 32 92 32 843 94.1 6.9 14 26 25 16 40 36 2359594.039 116132340.6 220813549.6 230256451.8 4 23 22 24 cell organization and biogenesis;metabolic process cytoplasm;cytosol;membrane protein binding "Pf07719, Pf13414, Pf13424, Pf13432, Pf14559" 104718 ENSMUSG00000033530.7 Ttc7b 12 0 High Q99JC1 Ig lambda-2 chain C region (Fragment) OS=Mus musculus OX=10090 GN=Iglc2 PE=1 SV=1 0 86.14 89 6 92 6 105 11.3 6.27 6 4 5 46 20 26 195834250.8 121131316.1 165506811.8 10186050.13 8 7 7 2 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding "Pf07654, Pf08205, Pf13927" 110786 ENSMUSG00000076937.3 Iglc2 16 0 High Q3V117 ATP-citrate synthase OS=Mus musculus OX=10090 GN=Acly PE=1 SV=1 0 127.877 35 33 92 33 1101 120.7 7.44 22 3 16 25 34 4 19 35 63043062.55 29937827.84 102988808.9 233884262 25 13 21 24 metabolic process cytoplasm;cytosol;membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00285, Pf00549, Pf02629, Pf08442" 104112 ENSMUSG00000020917.17 Acly 11 0 High P10126 Elongation factor 1-alpha 1 OS=Mus musculus OX=10090 GN=Eef1a1 PE=1 SV=3 0 85.926 50 17 91 17 462 50.1 9.01 16 13 11 14 29 19 18 25 93466019.88 97719033.16 122208672.4 366246458 15 15 13 16 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;nucleus catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00009, Pf03143, Pf03144" 13627 ENSMUSG00000037742.14 Eef1a1; LOC101056619 9 Legionellosis; RNA transport 0 High P48962 ADP/ATP translocase 1 OS=Mus musculus OX=10090 GN=Slc25a4 PE=1 SV=4 0 97.019 65 20 91 11 298 32.9 9.72 7 10 7 20 9 15 12 55 36730800.91 169800770.4 183929327.3 1922904945 12 16 16 22 Met-loss+Acetyl [N-Term] cell organization and biogenesis;regulation of biological process;transport membrane;mitochondrion;nucleus protein binding;transporter activity Pf00153 11739 ENSMUSG00000031633.4 Slc25a4 8 Regulation of insulin secretion HTLV-I infection; Huntington's disease; Parkinson's disease; cGMP-PKG signaling pathway; Calcium signaling pathway 10 High P63038 "60 kDa heat shock protein, mitochondrial OS=Mus musculus OX=10090 GN=Hspd1 PE=1 SV=1" 0 170.689 57 27 90 27 573 60.9 6.18 13 11 8 24 20 20 12 38 46252779.94 94746799.41 81864886.83 400345424.6 21 21 20 25 cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;cytosol;endoplasmic reticulum;endosome;Golgi;membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding;protein binding;RNA binding Pf00118 15510 ENSMUSG00000025980.14 Hspd1 1 RNA degradation; Tuberculosis; Legionellosis; Type I diabetes mellitus 0 High P17182 Alpha-enolase OS=Mus musculus OX=10090 GN=Eno1 PE=1 SV=3 0 135.678 69 23 87 23 434 47.1 6.8 17 13 14 15 27 17 17 26 95504922.41 96199401.06 96645349.5 207149070 23 17 16 17 metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;cytosol;membrane;nucleus catalytic activity;DNA binding;metal ion binding;protein binding;RNA binding "Pf00113, Pf03952, Pf13378" 13806; 433182 ENSMUSG00000059040.4; ENSMUSG00000063524.13 Eno1; Gm5506; Eno1b 4; 18 Gluconeogenesis; Glycolysis RNA degradation; Metabolic pathways; Biosynthesis of amino acids; Glycolysis / Gluconeogenesis; HIF-1 signaling pathway; Carbon metabolism 0 High Q62009 Periostin OS=Mus musculus OX=10090 GN=Postn PE=1 SV=2 0 161.774 54 36 87 36 838 93.1 7.53 32 16 16 3 46 18 20 3 132063786.8 92378077.22 97976563.75 35382827.5 34 23 23 10 cell communication;cell growth;cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;extracellular;Golgi metal ion binding;protein binding "Pf02469, Pf07546" 50706 ENSMUSG00000027750.16 Postn 3 0 High Q60936 "Atypical kinase COQ8A, mitochondrial OS=Mus musculus OX=10090 GN=Coq8a PE=1 SV=2" 0 143.575 45 22 87 22 645 71.7 6.54 7 9 10 22 11 13 13 50 21009273.34 76299479.36 84470916.51 594897828.7 14 19 17 23 metabolic process membrane;mitochondrion catalytic activity;nucleotide binding Pf03109 67426 ENSMUSG00000026489.13 Adck3; Coq8a 1 0 High P62137 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit OS=Mus musculus OX=10090 GN=Ppp1ca PE=1 SV=1 0 129.261 67 21 86 9 330 37.5 6.33 20 12 7 12 43 18 11 14 153945558.7 93461660.25 85147685 164462018.8 21 13 11 16 Met-loss+Acetyl [N-Term] cell division;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;nucleus catalytic activity;metal ion binding;protein binding Pf00149 19045 ENSMUSG00000040385.6; ENSMUSG00000096994.2 Ppp1ca 19; CHR_MG153_PATCH DARPP-32 events; Signaling by GPCR Oxytocin signaling pathway; mRNA surveillance pathway; Herpes simplex infection; Regulation of actin cytoskeleton; Dopaminergic synapse; Focal adhesion; Insulin signaling pathway; Long-term potentiation; Amphetamine addiction; Hippo signaling pathway; Platelet activation; Insulin resistance; Oocyte meiosis; Proteoglycans in cancer; cGMP-PKG signaling pathway; Alcoholism; cAMP signaling pathway; Vascular smooth muscle contraction; Adrenergic signaling in cardiomyocytes; Inflammatory mediator regulation of TRP channels 14 High Q925I1 ATPase family AAA domain-containing protein 3 OS=Mus musculus OX=10090 GN=Atad3 PE=1 SV=1 0 106.496 47 29 85 29 591 66.7 9.29 11 10 10 29 17 11 11 46 40187149.97 65794908 82332627.56 424483147 19 17 19 24 Met-loss+Acetyl [N-Term] cell growth;regulation of biological process membrane;mitochondrion catalytic activity;nucleotide binding;RNA binding "Pf00004, Pf00910, Pf01078, Pf05707, Pf06745, Pf07728, Pf12037, Pf13207, Pf13401" 108888 ENSMUSG00000029036.18 Atad3a 4 Neutrophil degranulation 0 High Q9Z1E4 "Glycogen [starch] synthase, muscle OS=Mus musculus OX=10090 GN=Gys1 PE=1 SV=2" 0 132.501 45 23 84 22 738 83.9 6.11 21 9 5 13 46 15 6 17 118335137.3 72073809.88 59207269.13 112636158.8 25 14 13 15 metabolic process cytoplasm;membrane catalytic activity;protein binding "Pf00534, Pf05693, Pf13579" 14936 ENSMUSG00000003865.16 Gys1 7 Glycogen synthesis Insulin signaling pathway; Metabolic pathways; Insulin resistance; Starch and sucrose metabolism; PI3K-Akt signaling pathway; AMPK signaling pathway; Glucagon signaling pathway 2 High P63268 "Actin, gamma-enteric smooth muscle OS=Mus musculus OX=10090 GN=Actg2 PE=1 SV=1" 0 86.214 47 15 84 6 376 41.9 5.48 10 6 9 15 19 12 16 37 11920001.88 15987382.5 21438297.25 99280020 5 4 3 5 regulation of biological process cytoplasm;cytoskeleton nucleotide binding Pf00022 11468 ENSMUSG00000059430.14 Actg2 6 Smooth Muscle Contraction Vascular smooth muscle contraction 0 High Q8BFR5 "Elongation factor Tu, mitochondrial OS=Mus musculus OX=10090 GN=Tufm PE=1 SV=1" 0 115.192 58 23 82 23 452 49.5 7.56 13 11 9 20 19 14 10 39 59331987.16 85628632.5 115969815.4 468626791 18 19 19 21 metabolic process;response to stimulus membrane;mitochondrion catalytic activity;nucleotide binding;RNA binding "Pf00009, Pf03143, Pf03144" 233870 ENSMUSG00000073838.10 Tufm 7 0 High Q9D2G2 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Mus musculus OX=10090 GN=Dlst PE=1 SV=1" 0 69.237 37 14 81 14 454 49 8.95 13 11 12 6 34 16 21 10 206763845.8 140984256.6 241749579.8 163524712.8 16 11 13 9 metabolic process membrane;mitochondrion;nucleus catalytic activity;protein binding "Pf00198, Pf00364" 78920 ENSMUSG00000004789.9 Dlst 12 Lysine catabolism; Citric acid cycle (TCA cycle); Glyoxylate metabolism and glycine degradation Citrate cycle (TCA cycle); Metabolic pathways; Lysine degradation; Carbon metabolism 0 High P01644 Ig kappa chain V-V region HP R16.7 OS=Mus musculus OX=10090 PE=1 SV=1 0 64.901 61 5 80 4 108 11.9 7.97 5 5 5 4 42 12 15 11 385400555.9 226987282 249643518.5 193926672.3 7 5 5 5 Acetyl [N-Term] "Pf00047, Pf07679, Pf07686" 56304 Ce9 6 2 High A0A0A6YXW6 Immunoglobulin heavy constant alpha (Fragment) OS=Mus musculus OX=10090 GN=Igha PE=1 SV=1 0 113.174 31 10 80 10 389 42 4.94 10 9 9 7 29 18 21 12 203079054.5 189506621.1 153353343 78660896.75 13 12 11 7 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07654 ENSMUSG00000095079.6 12 Cell surface interactions at the vascular wall; Scavenging of heme from plasma 0 High A0A0U1RP81 MICOS complex subunit MIC60 OS=Mus musculus OX=10090 GN=Immt PE=1 SV=1 0 131.78 61 32 80 3 488 53.7 8.66 16 6 6 29 23 7 8 42 572655.625 2341730.5 4113194.5 21867409.75 1 1 1 2 cellular homeostasis membrane;mitochondrion Pf09731 ENSMUSG00000052337.15 6 0 High P42125 "Enoyl-CoA delta isomerase 1, mitochondrial OS=Mus musculus OX=10090 GN=Eci1 PE=1 SV=2" 0 89.736 66 15 79 15 289 32.2 8.98 9 11 8 15 20 18 12 29 120076813.5 142075692.6 149228110.6 418441037.5 14 14 14 16 metabolic process membrane;mitochondrion;organelle lumen catalytic activity;protein binding Pf00378 13177 ENSMUSG00000024132.5 Eci1 17 mitochondrial fatty acid beta-oxidation of unsaturated fatty acids Fatty acid degradation 0 High Q9CQA3 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Mus musculus OX=10090 GN=Sdhb PE=1 SV=1" 0 83.801 61 20 78 20 282 31.8 8.68 9 11 11 19 16 14 14 34 80489358.08 141245698 123489006.5 392741630.5 19 18 16 20 metabolic process;transport membrane;mitochondrion catalytic activity;metal ion binding "Pf13085, Pf13183, Pf13534" 67680 ENSMUSG00000009863.14 Sdhb 4 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Carbon metabolism 0 High A2A513 "Keratin, type I cytoskeletal 10 OS=Mus musculus OX=10090 GN=Krt10 PE=1 SV=1" 0 44.946 15 11 77 9 561 57 5.07 9 5 8 9 25 12 17 23 282100847.8 194060330.5 205969042.9 549822649.5 12 10 11 11 cell differentiation;cell organization and biogenesis;metabolic process;response to stimulus cytoplasm;cytoskeleton;membrane;nucleus protein binding;structural molecule activity Pf00038 16661 ENSMUSG00000019761.10 Krt10 11 Formation of the cornified envelope Staphylococcus aureus infection 2 High Q5SWU9 Acetyl-CoA carboxylase 1 OS=Mus musculus OX=10090 GN=Acaca PE=1 SV=1 0 150.24 21 41 76 34 2345 265.1 6.39 21 2 6 34 25 2 7 42 40375410.16 8402509.5 45610249 241939279 31 4 17 36 cell organization and biogenesis;metabolic process;response to stimulus cytoplasm;cytoskeleton;cytosol;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00289, Pf00364, Pf01039, Pf02222, Pf02655, Pf02785, Pf02786, Pf07478, Pf08326, Pf13535, Pf15632" 107476 ENSMUSG00000020532.18 Acaca 11 ChREBP activates metabolic gene expression; Biotin transport and metabolism; Fatty acyl-CoA biosynthesis; Import of palmitoyl-CoA into the mitochondrial matrix Fatty acid metabolism; Pyruvate metabolism; Insulin signaling pathway; Metabolic pathways; Propanoate metabolism; AMPK signaling pathway; Fatty acid biosynthesis; Glucagon signaling pathway 8 High O54724 Caveolae-associated protein 1 OS=Mus musculus OX=10090 GN=Cavin1 PE=1 SV=1 0 95.658 51 19 76 19 392 43.9 5.52 14 7 17 10 23 13 28 12 65249461.75 96054856.63 181125795 105522366.3 17 14 16 13 Acetyl [N-Term] metabolic process;regulation of biological process cytoplasm;cytosol;endoplasmic reticulum;membrane;mitochondrion;nucleus protein binding;RNA binding Pf15237 19285 ENSMUSG00000004044.9 Ptrf; Cavin1 11 RNA Polymerase I Transcription Termination 0 High Q9Z1R9 "Protease, serine 1 (trypsin 1) OS=Mus musculus OX=10090 GN=Prss1 PE=1 SV=1" 0 36.843 8 1 76 1 246 26.1 4.94 1 1 1 1 24 17 21 14 1412112193 984484508 1020429957 1310375709 2 2 2 2 metabolic process catalytic activity Pf00089 114228 ENSMUSG00000062751.5 Prss1 6 "Cobalamin (Cbl, vitamin B12) transport and metabolism; Neutrophil degranulation; Collagen degradation; Antimicrobial peptides; Activation of Matrix Metalloproteinases" 0 High E9QNN1 DEAH box protein 9 OS=Mus musculus OX=10090 GN=Dhx9 PE=1 SV=1 0 116.446 24 29 75 29 1384 149.6 6.83 27 13 10 6 42 15 11 7 117965825.1 70502092.34 53429553.78 58957229.38 27 19 17 16 cell death;cell differentiation;cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;membrane;nucleus;ribosome catalytic activity;DNA binding;metal ion binding;nucleotide binding;protein binding;RNA binding "Pf00035, Pf00270, Pf00271, Pf04408, Pf07717" 13211 ENSMUSG00000042699.11 Dhx9 1 DEx/H-box helicases activate type I IFN and inflammatory cytokines production ; Activated TLR4 signalling; mRNA Splicing - Major Pathway; TAK1 activates NFkB by phosphorylation and activation of IKKs complex; RIP-mediated NFkB activation via ZBP1; TRAF6 mediated NF-kB activation; Interleukin-1 family signaling 0 High Q99LC5 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Mus musculus OX=10090 GN=Etfa PE=1 SV=2" 0 133.102 72 20 74 20 333 35 8.38 7 12 10 20 9 16 14 35 40765118.67 134198031.4 86953205.38 434020362.5 15 16 15 18 metabolic process;transport mitochondrion;organelle lumen catalytic activity;nucleotide binding;protein binding "Pf00766, Pf01012" 110842 ENSMUSG00000032314.14 Etfa 9 Respiratory electron transport 0 High Q8VEK3 Heterogeneous nuclear ribonucleoprotein U OS=Mus musculus OX=10090 GN=Hnrnpu PE=1 SV=1 0 87.361 33 23 73 23 800 87.9 6.24 20 12 14 8 30 15 18 10 111561717.6 122575548.4 119362043.8 105473069.1 20 19 17 15 cell differentiation;metabolic process;regulation of biological process;response to stimulus cell surface;chromosome;cytoplasm;membrane;nucleus;spliceosomal complex DNA binding;nucleotide binding;protein binding;RNA binding "Pf00622, Pf13671" 51810 ENSMUSG00000039630.10; ENSMUSG00000111145.1 Hnrnpu 1; CHR_MG4281_PATCH mRNA Splicing - Major Pathway Spliceosome 0 High Q9EQK5 Major vault protein OS=Mus musculus OX=10090 GN=Mvp PE=1 SV=4 0 113.545 43 28 73 28 861 95.9 5.59 27 15 12 2 41 17 12 3 97080243.23 58356552 62789519.16 32357476.25 27 19 19 12 Met-loss+Acetyl [N-Term] cell proliferation;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;nucleus protein binding "Pf01145, Pf01505, Pf11978" 78388 Mvp 7 0 High Q8BG05 Heterogeneous nuclear ribonucleoprotein A3 OS=Mus musculus OX=10090 GN=Hnrnpa3 PE=1 SV=1 0 108.135 46 17 72 16 379 39.6 9.01 14 11 10 12 27 18 12 15 157281155.2 217541231.8 145631652.3 203363250.9 16 15 14 15 Acetyl [N-Term] metabolic process;transport cytoplasm;nucleus;spliceosomal complex RNA binding;transporter activity "Pf00076, Pf13893, Pf14259" 229279 ENSMUSG00000059005.13 Hnrnpa3 2 Spliceosome 1 High Q9EQ20 "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Mus musculus OX=10090 GN=Aldh6a1 PE=1 SV=1" 0 92.766 39 19 72 19 535 57.9 8.07 14 9 9 16 22 13 11 26 88194173.75 119016491.9 73932881.13 235729750.6 17 15 14 17 cell differentiation;metabolic process mitochondrion catalytic activity;RNA binding Pf00171 104776 ENSMUSG00000021238.10 Aldh6a1 12 Branched-chain amino acid catabolism "Valine, leucine and isoleucine degradation; Metabolic pathways; beta-Alanine metabolism; Propanoate metabolism; Inositol phosphate metabolism; Carbon metabolism" 0 High P13707 "Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic OS=Mus musculus OX=10090 GN=Gpd1 PE=1 SV=3" 0 118.636 65 21 71 21 349 37.5 7.17 17 9 9 16 22 14 14 21 201661439.6 222092186.6 224016038.3 293825107.9 19 17 17 17 metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;mitochondrion catalytic activity;nucleotide binding;protein binding "Pf01210, Pf07479" 14555 ENSMUSG00000023019.12 Gpd1 15 Synthesis of PA Glycerophospholipid metabolism 0 High Q3TML0 Protein disulfide-isomerase A6 OS=Mus musculus OX=10090 GN=Pdia6 PE=1 SV=1 0 198.125 63 24 71 24 445 48.7 5.19 7 4 24 8 4 59 17924621.81 19659108.3 1037230709 11 7 21 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytosol;endoplasmic reticulum;membrane;organelle lumen catalytic activity "Pf00085, Pf13098, Pf13848, Pf13899, Pf13905" 71853 ENSMUSG00000020571.12 Pdia6 12 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation Protein processing in endoplasmic reticulum 0 High Q3TTY5 "Keratin, type II cytoskeletal 2 epidermal OS=Mus musculus OX=10090 GN=Krt2 PE=1 SV=1" 0 39.33 10 11 71 6 707 70.9 8.06 9 8 7 8 26 12 11 22 133568893.2 85246186 117742851.1 530355014.5 8 7 7 7 cell organization and biogenesis;cell proliferation;cellular component movement;metabolic process cytoskeleton;membrane;nucleus protein binding;structural molecule activity "Pf00038, Pf13166" 16681 ENSMUSG00000064201.8 Krt2 15 Formation of the cornified envelope 0 High P04104 "Keratin, type II cytoskeletal 1 OS=Mus musculus OX=10090 GN=Krt1 PE=1 SV=4" 0 34.512 7 7 70 3 637 65.6 8.15 5 5 3 5 23 11 11 25 633971991.6 377770527 243231198.3 1123853726 5 4 4 5 defense response;metabolic process;regulation of biological process;response to stimulus cytoskeleton;membrane;nucleus structural molecule activity "Pf00038, Pf11853" 16678 ENSMUSG00000046834.6 Krt1 15 Formation of the cornified envelope; Neutrophil degranulation 2 High Q9D051 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Mus musculus OX=10090 GN=Pdhb PE=1 SV=1" 0 100.11 55 15 70 15 359 38.9 6.87 10 8 9 13 23 9 13 25 118505471.6 57420423.55 98361300.73 231774311.8 15 10 13 15 metabolic process mitochondrion;nucleus;organelle lumen catalytic activity "Pf02779, Pf02780" 68263 ENSMUSG00000021748.8 Pdhb 14 Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Glyoxylate metabolism and glycine degradation Pyruvate metabolism; Citrate cycle (TCA cycle); Metabolic pathways; Glycolysis / Gluconeogenesis; HIF-1 signaling pathway; Carbon metabolism; Central carbon metabolism in cancer; Glucagon signaling pathway 0 High P40142 Transketolase OS=Mus musculus OX=10090 GN=Tkt PE=1 SV=1 0 175.294 57 29 70 29 623 67.6 7.5 6 2 4 29 6 3 4 57 10770731.13 14953284.5 24001613 529896712.6 10 7 9 27 Acetyl [N-Term] metabolic process;regulation of biological process membrane catalytic activity;metal ion binding;protein binding "Pf00456, Pf00676, Pf02779, Pf02780" 21881 ENSMUSG00000021957.6 Tkt 14 Pentose phosphate pathway (hexose monophosphate shunt); Insulin effects increased synthesis of Xylulose-5-Phosphate Metabolic pathways; Biosynthesis of amino acids; Pentose phosphate pathway; Carbon metabolism 0 High Q8C767 Protein phosphatase 1 regulatory subunit 3B OS=Mus musculus OX=10090 GN=Ppp1r3b PE=1 SV=1 0 74.99 53 14 70 14 284 32.4 5.87 14 9 8 6 34 14 13 9 200993559.7 129178571.6 82579406.63 175265235 15 12 11 14 Met-loss+Acetyl [N-Term] metabolic process;regulation of biological process catalytic activity;enzyme regulator activity;protein binding Pf03370 244416 ENSMUSG00000046794.9 Ppp1r3b 8 Insulin signaling pathway; Insulin resistance 0 High O08528 Hexokinase-2 OS=Mus musculus OX=10090 GN=Hk2 PE=1 SV=1 0 131.352 44 32 69 32 917 102.5 6.11 9 4 17 28 10 4 19 36 27107094.19 30281232.81 89634003.75 331036050.5 19 14 23 29 Acetyl [N-Term] cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytosol;membrane;mitochondrion catalytic activity;nucleotide binding;protein binding "Pf00349, Pf03727" 15277 ENSMUSG00000000628.10 Hk2 6 Glycolysis "Neomycin, kanamycin and gentamicin biosynthesis; Type II diabetes mellitus; Carbohydrate digestion and absorption; Insulin signaling pathway; Metabolic pathways; Amino sugar and nucleotide sugar metabolism; Starch and sucrose metabolism; Glycolysis / Gluconeogenesis; HIF-1 signaling pathway; Carbon metabolism; Fructose and mannose metabolism; Galactose metabolism; Central carbon metabolism in cancer" 0 High P62141 Serine/threonine-protein phosphatase PP1-beta catalytic subunit OS=Mus musculus OX=10090 GN=Ppp1cb PE=1 SV=3 0 115.009 64 20 69 8 327 37.2 6.19 19 10 4 9 36 15 7 11 39526800.78 26202345.73 16579702.31 37438400.5 8 7 5 5 Met-loss+Acetyl [N-Term] cell division;metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus catalytic activity;metal ion binding;protein binding Pf00149 19046 ENSMUSG00000014956.15 Ppp1cb 5 RHO GTPases activate PAKs; Regulation of PLK1 Activity at G2/M Transition; RHO GTPases activate PKNs Oxytocin signaling pathway; mRNA surveillance pathway; Herpes simplex infection; Regulation of actin cytoskeleton; Dopaminergic synapse; Focal adhesion; Insulin signaling pathway; Long-term potentiation; Amphetamine addiction; Hippo signaling pathway; Platelet activation; Insulin resistance; Oocyte meiosis; Proteoglycans in cancer; cGMP-PKG signaling pathway; Alcoholism; cAMP signaling pathway; Vascular smooth muscle contraction; Adrenergic signaling in cardiomyocytes; Inflammatory mediator regulation of TRP channels 0 High P11152 Lipoprotein lipase OS=Mus musculus OX=10090 GN=Lpl PE=1 SV=3 0 125.014 56 21 69 21 474 53.1 7.87 7 2 1 21 10 2 1 56 22242478.69 15360638.75 9701850.25 1345420561 9 5 4 21 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cell surface;extracellular;membrane catalytic activity;protein binding "Pf00151, Pf01477, Pf12695, Pf12697" 16956 ENSMUSG00000015568.16 Lpl 8 Assembly of active LPL and LIPC lipase complexes; Chylomicron remodeling; Signaling by GPCR; Retinoid metabolism and transport PPAR signaling pathway; Alzheimer's disease; Glycerolipid metabolism 0 High Q9DCW4 Electron transfer flavoprotein subunit beta OS=Mus musculus OX=10090 GN=Etfb PE=1 SV=3 0 85.562 58 15 69 15 255 27.6 8.1 8 8 7 14 13 13 12 31 43334303.56 86260249.25 60246134.88 334801560 12 11 9 14 metabolic process;transport cytosol;mitochondrion;organelle lumen Pf01012 110826 ENSMUSG00000004610.4 Etfb 7 Protein methylation; Respiratory electron transport 0 High P51660 Peroxisomal multifunctional enzyme type 2 OS=Mus musculus OX=10090 GN=Hsd17b4 PE=1 SV=3 0 92.019 39 20 68 20 735 79.4 8.57 16 8 13 10 31 9 16 12 103843166.9 68233809.75 86295194.56 103681634.5 17 13 15 16 cell differentiation;metabolic process membrane;mitochondrion catalytic activity;protein binding "Pf00106, Pf01575, Pf02036, Pf08659, Pf13452, Pf13561, Pf14864" 15488 ENSMUSG00000024507.6 Hsd17b4 18 Beta-oxidation of pristanoyl-CoA; Beta-oxidation of very long chain fatty acids; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; alpha-linolenic acid (ALA) metabolism Metabolic pathways; Primary bile acid biosynthesis; Peroxisome 0 High A0A5F8MPH8 Tenascin XB OS=Mus musculus OX=10090 GN=Tnxb PE=1 SV=1 0 136.785 15 36 68 36 4356 473.8 5.39 35 6 5 1 55 6 6 1 79152706.88 41898600.69 38240106.75 25863094.25 32 11 10 7 0 High O08648 Mitogen-activated protein kinase kinase kinase 4 OS=Mus musculus OX=10090 GN=Map3k4 PE=1 SV=2 0 98.066 19 25 68 25 1597 179.7 6.43 12 22 18 17 27 24 1074976 69201698.72 101205874.6 123065454.8 2 19 18 19 cell differentiation;metabolic process;regulation of biological process;response to stimulus cytoplasm catalytic activity;metal ion binding;nucleotide binding;protein binding;signal transducer activity "Pf00069, Pf07714, Pf14531" 26407 ENSMUSG00000014426.8 Map3k4 17 MAPK signaling pathway; GnRH signaling pathway 0 High P16015 Carbonic anhydrase 3 OS=Mus musculus OX=10090 GN=Ca3 PE=1 SV=3 0 93.31 77 17 66 17 260 29.3 7.37 16 6 8 6 34 10 14 8 126125031.4 56274396 113432288.1 84038722.63 17 10 14 9 metabolic process;response to stimulus cytoplasm;cytosol catalytic activity;metal ion binding Pf00194 12350 ENSMUSG00000027559.5 Car3 3 Reversible hydration of carbon dioxide Nitrogen metabolism 0 High P45952 "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Acadm PE=1 SV=1" 0 86.489 48 18 66 18 421 46.5 8.37 9 7 8 16 14 11 11 30 44783488.56 68134743.41 59830398.81 269027794.5 14 11 11 16 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion;nucleus;organelle lumen catalytic activity;nucleotide binding;protein binding "Pf00441, Pf02770, Pf02771, Pf08028" 11364 ENSMUSG00000062908.12 Acadm 3 mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA "PPAR signaling pathway; Fatty acid metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Fatty acid degradation; beta-Alanine metabolism; Propanoate metabolism; Carbon metabolism" 0 High P04117 "Fatty acid-binding protein, adipocyte OS=Mus musculus OX=10090 GN=Fabp4 PE=1 SV=3" 0 38.346 77 9 66 9 132 14.6 8.4 8 7 8 7 20 17 15 14 137781533.5 179238814.5 159816353 203451420 9 9 8 8 Met-loss+Acetyl [N-Term] cell differentiation;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;nucleus transporter activity Pf00061 11770 ENSMUSG00000062515.3 Fabp4 3 Triglyceride catabolism; Mus musculus biological processes; Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes PPAR signaling pathway; Regulation of lipolysis in adipocytes 0 High A0A1L1STE6 "Isocitrate dehydrogenase [NAD] subunit, mitochondrial OS=Mus musculus OX=10090 GN=Idh3a PE=1 SV=1" 0 73.39 41 16 65 16 384 41.5 6.93 14 10 8 11 22 16 8 19 52087892.31 86940184.2 59882606.13 218460646 17 11 11 15 metabolic process mitochondrion catalytic activity;metal ion binding;nucleotide binding Pf00180 ENSMUSG00000032279.11 9 0 High A8DUK4 Beta-globin OS=Mus musculus OX=10090 GN=Hbb-bs PE=1 SV=1 0 77.729 96 14 64 14 147 15.7 7.69 9 11 11 10 14 20 15 15 115821965 234703459.5 172826363.5 233926600.8 12 13 13 12 Met-loss [N-Term] regulation of biological process;transport antioxidant activity;catalytic activity;metal ion binding;protein binding;transporter activity Pf00042 100503605; 101488143; 15129 ENSMUSG00000073940.3; ENSMUSG00000052305.6 Beta-s; Hbb-bs; Hbb-bt; Hbb-b1 7 Erythrocytes take up carbon dioxide and release oxygen; Neutrophil degranulation; Factors involved in megakaryocyte development and platelet production; Erythrocytes take up oxygen and release carbon dioxide; Scavenging of heme from plasma African trypanosomiasis; Malaria 0 High Q8QZT1 "Acetyl-CoA acetyltransferase, mitochondrial OS=Mus musculus OX=10090 GN=Acat1 PE=1 SV=1" 0 108.961 57 18 64 18 424 44.8 8.51 10 8 10 15 17 10 14 23 68703290.13 85527629.75 83289711.25 223175249.3 18 16 15 18 cell organization and biogenesis;metabolic process;response to stimulus membrane;mitochondrion;organelle lumen catalytic activity;metal ion binding;protein binding "Pf00108, Pf00109, Pf02803" 110446 ENSMUSG00000032047.5 Acat1 9 Synthesis of Ketone Bodies; Utilization of Ketone Bodies; Branched-chain amino acid catabolism "Fatty acid metabolism; Pyruvate metabolism; Tryptophan metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Terpenoid backbone biosynthesis; Lysine degradation; Fatty acid degradation; Butanoate metabolism; Propanoate metabolism; Synthesis and degradation of ketone bodies; Carbon metabolism; Glyoxylate and dicarboxylate metabolism" 0 High Q8VCT4 Carboxylesterase 1D OS=Mus musculus OX=10090 GN=Ces1d PE=1 SV=1 0 147.632 61 25 64 24 565 61.7 6.61 4 7 24 4 7 53 16130530.66 23682711.23 7012173.375 1000161496 14 10 3 23 cell differentiation;cell organization and biogenesis;metabolic process;response to stimulus cytoplasm;cytosol;endoplasmic reticulum;organelle lumen catalytic activity "Pf00135, Pf00326, Pf00756, Pf07859, Pf12695" 104158 ENSMUSG00000056973.6 Ces1d 8 Phase I - Functionalization of compounds Metabolic pathways; Drug metabolism - other enzymes 1 High A0A087WS16 "Collagen, type VI, alpha 3 OS=Mus musculus OX=10090 GN=Col6a3 PE=1 SV=1" 0 124.186 17 32 64 32 2677 288.5 8.53 30 6 12 3 42 6 13 3 77497487.05 28759595.31 49730395.31 17686217.53 31 15 19 7 regulation of biological process extracellular;membrane enzyme regulator activity;protein binding "Pf00014, Pf00041, Pf00092, Pf01391, Pf13519, Pf13768" ENSMUSG00000048126.16 1 ECM proteoglycans; Collagen chain trimerization; Integrin cell surface interactions; NCAM1 interactions; Collagen degradation; Signaling by PDGF; Assembly of collagen fibrils and other multimeric structures 0 High P84089 Enhancer of rudimentary homolog OS=Mus musculus OX=10090 GN=Erh PE=1 SV=1 0 41.375 61 8 62 8 104 12.3 5.92 2 8 8 8 3 19 21 19 7227168 400960351.3 636017358.6 591246570 5 8 8 8 Met-loss+Acetyl [N-Term] cell differentiation;metabolic process;regulation of biological process membrane DNA binding;nucleotide binding;RNA binding Pf01133 13877 ENSMUSG00000021131.14; ENSMUSG00000063412.4 Erh 12; 8 0 High P98086 Complement C1q subcomponent subunit A OS=Mus musculus OX=10090 GN=C1qa PE=1 SV=2 0 44.263 38 8 61 8 245 26 9.11 8 4 4 5 22 12 12 15 464387863.1 406471000 486545443.5 351672564.5 8 6 6 5 defense response;metabolic process;regulation of biological process;response to stimulus extracellular;membrane protein binding "Pf00229, Pf00386" 12259 ENSMUSG00000036887.5 C1qa 4 Regulation of Complement cascade; Classical antibody-mediated complement activation Chagas disease (American trypanosomiasis); Staphylococcus aureus infection; Complement and coagulation cascades; Pertussis; Prion diseases; Systemic lupus erythematosus 0 High Q6P3A8 "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial OS=Mus musculus OX=10090 GN=Bckdhb PE=1 SV=2" 0 111.689 63 15 59 15 390 42.9 6.7 13 5 6 8 25 8 11 15 100508872.6 48909747 74557018 98402969.75 12 9 10 9 metabolic process membrane;mitochondrion;organelle lumen catalytic activity;protein binding "Pf02779, Pf02780" 12040 ENSMUSG00000032263.14 Bckdhb 9 Glyoxylate metabolism and glycine degradation; Branched-chain amino acid catabolism "Valine, leucine and isoleucine degradation; Metabolic pathways; Propanoate metabolism" 0 High Q6IFZ6 "Keratin, type II cytoskeletal 1b OS=Mus musculus OX=10090 GN=Krt77 PE=1 SV=1" 0 27.57 8 6 59 1 572 61.3 8.02 4 4 3 5 21 9 9 20 69859296 21424458 22380020 133094600 1 1 1 1 cytoskeleton protein binding;structural molecule activity "Pf00038, Pf09728, Pf13166" 406220 ENSMUSG00000067594.5 Krt77 15 Formation of the cornified envelope 0 High A0A1W2P7F1 "Complement component 1, s subcomponent 2 OS=Mus musculus OX=10090 GN=C1s2 PE=1 SV=1" 0 78.381 25 14 59 1 694 77.2 4.94 13 6 8 4 27 10 15 7 11385135.25 3808210.75 10269429 2990827.75 1 1 1 1 defense response;metabolic process;regulation of biological process;response to stimulus extracellular catalytic activity;metal ion binding;protein binding "Pf00084, Pf00089, Pf00431, Pf07645, Pf14670" 317677 ENSMUSG00000079343.4 Gm5077; C1s2 6 Staphylococcus aureus infection; Complement and coagulation cascades; Pertussis; Systemic lupus erythematosus 0 High P62702 "40S ribosomal protein S4, X isoform OS=Mus musculus OX=10090 GN=Rps4x PE=1 SV=2" 0 56.188 63 18 59 18 263 29.6 10.15 8 12 13 15 11 12 17 19 22646260.5 81370223 97783923 153537922 12 15 15 15 development;metabolic process;regulation of biological process cytoplasm;membrane;nucleus;ribosome RNA binding;structural molecule activity "Pf00900, Pf08071" 20102 ENSMUSG00000031320.9 Rps4x X "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High A0A0A6YY53 Immunoglobulin heavy constant gamma 2C (Fragment) OS=Mus musculus OX=10090 GN=Ighg2c PE=1 SV=1 0 70.555 35 7 59 6 335 36.5 8.02 6 4 5 3 24 11 16 8 69229755.63 39799289.25 73580117.5 8304341.75 6 6 6 2 defense response;response to stimulus Pf07654 ENSMUSG00000076612.7 LOC100048855 12 Regulation of Complement cascade; Role of phospholipids in phagocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR activation; Classical antibody-mediated complement activation 0 High P35700 Peroxiredoxin-1 OS=Mus musculus OX=10090 GN=Prdx1 PE=1 SV=1 0 35.29 73 13 58 13 199 22.2 8.12 9 7 9 10 17 13 13 15 59288234.75 59942964 77837969 165551120.6 11 9 9 10 cell proliferation;cellular homeostasis;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;mitochondrion;nucleus;organelle lumen antioxidant activity;catalytic activity;protein binding;RNA binding "Pf00578, Pf08534, Pf10417" 18477 ENSMUSG00000028691.12 Prdx1 4 Detoxification of Reactive Oxygen Species; TP53 Regulates Metabolic Genes Peroxisome 0 High O08749 "Dihydrolipoyl dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Dld PE=1 SV=2" 0 77.645 39 17 56 17 509 54.2 7.9 9 4 5 16 15 6 7 28 41587594.63 28486263.5 58888238.5 190731075.5 14 9 15 17 cellular homeostasis;metabolic process;regulation of biological process mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf00070, Pf00890, Pf01134, Pf01946, Pf02852, Pf03486, Pf07992, Pf12831, Pf13450" 13382 ENSMUSG00000020664.10 Dld 12 Glycine degradation; Signaling by Retinoic Acid; Citric acid cycle (TCA cycle); Lysine catabolism; Regulation of pyruvate dehydrogenase (PDH) complex; Branched-chain amino acid catabolism "Pyruvate metabolism; Citrate cycle (TCA cycle); Valine, leucine and isoleucine degradation; Metabolic pathways; Glycine, serine and threonine metabolism; Glycolysis / Gluconeogenesis; Propanoate metabolism; Carbon metabolism; Glyoxylate and dicarboxylate metabolism" 0 High Q8R0Y8 Mitochondrial coenzyme A transporter SLC25A42 OS=Mus musculus OX=10090 GN=Slc25a42 PE=1 SV=1 0 123.557 60 16 55 16 318 35.2 10.05 2 1 6 16 3 2 7 43 6965647.469 27306421.5 42124285.25 548253014.8 6 7 8 17 Met-loss [N-Term] transport membrane;mitochondrion;nucleus catalytic activity;transporter activity Pf00153 73095 ENSMUSG00000002346.16 Slc25a42 8 0 High P59913 Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 OS=Mus musculus OX=10090 GN=Pcmtd1 PE=1 SV=1 0 48.183 48 15 55 15 357 40.7 5.66 15 6 7 5 27 8 12 8 112231406.4 64174081.75 85883267 87926579.5 11 9 9 8 metabolic process cytoplasm;membrane catalytic activity "Pf01135, Pf12847, Pf13847" 319263 ENSMUSG00000051285.17 Pcmtd1 1 0 High Q9Z1A1 TFG protein OS=Mus musculus OX=10090 GN=Tfg PE=1 SV=1 0 52.463 36 8 55 8 397 43 5.1 8 6 6 5 22 12 9 12 108915599.6 109356720.1 60122089.13 82417098.5 8 8 7 6 cell organization and biogenesis;regulation of biological process;response to stimulus;transport membrane protein binding;signal transducer activity "Pf00564, Pf08232" 21787 ENSMUSG00000022757.18 Tfg 16 COPII (Coat Protein 2) Mediated Vesicle Transport 0 High P11499 Heat shock protein HSP 90-beta OS=Mus musculus OX=10090 GN=Hsp90ab1 PE=1 SV=3 0 97.935 35 22 52 20 724 83.2 5.03 1 2 3 22 1 3 4 44 4961184.656 3539224.25 13432943.13 167912590.4 10 2 6 18 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;cytosol;extracellular;membrane;mitochondrion;nucleus enzyme regulator activity;nucleotide binding;protein binding;RNA binding "Pf00183, Pf02518, Pf13589" 15516 ENSMUSG00000023944.14 Hsp90ab1 17 The role of GTSE1 in G2/M progression after G2 checkpoint; HSF1 activation; Attenuation phase; Neutrophil degranulation; The NLRP3 inflammasome; HSP90 chaperone cycle for steroid hormone receptors (SHR); Regulation of actin dynamics for phagocytic cup formation; Aryl hydrocarbon receptor signalling; Sema3A PAK dependent Axon repulsion Progesterone-mediated oocyte maturation; NOD-like receptor signaling pathway; Pathways in cancer; Antigen processing and presentation; PI3K-Akt signaling pathway; Protein processing in endoplasmic reticulum; Estrogen signaling pathway; Prostate cancer 0 High Q62425 Cytochrome c oxidase subunit NDUFA4 OS=Mus musculus OX=10090 GN=Ndufa4 PE=1 SV=2 0 42.127 87 9 51 9 82 9.3 9.52 5 6 5 9 9 9 10 23 52652338.36 128897002.6 157431375 1574292653 6 6 6 10 metabolic process;transport membrane;mitochondrion catalytic activity;protein binding;transporter activity Pf06522 17992 ENSMUSG00000029632.7 Ndufa4 6 Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High A2AJW4 "Protein phosphatase 1, regulatory subunit 3D OS=Mus musculus OX=10090 GN=Ppp1r3d PE=1 SV=1" 0 55.619 61 14 51 14 279 30.5 8.25 14 7 11 30 10 11 176073119.2 62286403 2738973 108461000.5 14 11 1 10 metabolic process;regulation of biological process catalytic activity;protein binding Pf03370 228966 ENSMUSG00000049999.4 Ppp1r3d 2 Insulin signaling pathway; Insulin resistance 0 High Q8C2Q7 Heterogeneous nuclear ribonucleoprotein H OS=Mus musculus OX=10090 GN=Hnrnph1 PE=1 SV=1 0 75.851 39 14 51 4 472 51.2 6.8 13 6 7 7 25 8 10 8 79725901.44 45494044.44 50106823.01 45904967.92 13 11 11 9 Acetyl [N-Term] metabolic process;regulation of biological process cytosol;membrane;nucleus;spliceosomal complex protein binding;RNA binding "Pf00076, Pf08080, Pf14259" 59013 ENSMUSG00000007850.16 Hnrnph1 11 10 High Q91YW3 DnaJ homolog subfamily C member 3 OS=Mus musculus OX=10090 GN=Dnajc3 PE=1 SV=1 0 164.784 60 27 50 27 504 57.4 5.85 27 50 2637755 4534309 277001312 1 2 19 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;endoplasmic reticulum;membrane;organelle lumen enzyme regulator activity;protein binding "Pf00226, Pf00515, Pf13371, Pf13414, Pf13424, Pf14559" 100037258 ENSMUSG00000022136.7 Dnajc3 14 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Neutrophil degranulation; Post-translational protein phosphorylation Influenza A; Protein processing in endoplasmic reticulum 0 High Q91YQ5 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Mus musculus OX=10090 GN=Rpn1 PE=1 SV=1 0 138.837 58 27 50 27 608 68.5 6.46 27 50 1495098.336 571465568 3 24 metabolic process cytosol;endoplasmic reticulum;membrane catalytic activity;RNA binding Pf04597 103963 ENSMUSG00000030062.7 Rpn1 6 Metabolic pathways; N-Glycan biosynthesis; Protein processing in endoplasmic reticulum 0 High A0A286YCQ5 Nidogen-2 (Fragment) OS=Mus musculus OX=10090 GN=Nid2 PE=1 SV=1 0 92.566 28 22 49 22 1171 128.4 5.76 21 4 3 1 39 6 3 1 91501433.81 32541749.88 25904473.88 7855447.5 22 13 10 3 0 High A0A0B4J1J7 Immunoglobulin heavy variable 1-82 OS=Mus musculus OX=10090 GN=Ighv1-82 PE=1 SV=1 0 28.743 64 5 49 3 98 10.6 9.29 5 3 4 4 22 8 10 9 205981937 181805066.3 166423564.5 106959813.3 4 3 4 2 Pf07686 16061 ENSMUSG00000095127.2 Igh-VJ558 12 0 High E9QQ30 Eukaryotic translation initiation factor 2-alpha kinase 3 OS=Mus musculus OX=10090 GN=Eif2ak3 PE=1 SV=1 0 97.285 35 27 49 27 1114 124.6 5.25 14 21 18 31 2240584.016 111167568.1 1357000.875 198727347.8 4 20 1 22 cell communication;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;membrane catalytic activity;nucleotide binding;protein binding "Pf00069, Pf07714, Pf13360, Pf14531" 13666 ENSMUSG00000031668.14 Eif2ak3 6 PERK regulates gene expression 0 High P68372 Tubulin beta-4B chain OS=Mus musculus OX=10090 GN=Tubb4b PE=1 SV=1 0 97.355 66 22 48 1 445 49.8 4.89 3 3 7 22 5 3 7 33 15604769.63 31639774.63 52786693.5 249202715.5 10 9 10 18 cell organization and biogenesis cytoplasm;cytoskeleton;nucleus catalytic activity;nucleotide binding;RNA binding;structural molecule activity "Pf00091, Pf03953, Pf10644" 227613 ENSMUSG00000036752.4 Tubb4b 2 Anchoring of the basal body to the plasma membrane; Intraflagellar transport; Hedgehog 'on' state; AURKA Activation by TPX2; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Hedgehog 'off' state; Regulation of PLK1 Activity at G2/M Transition; Neutrophil degranulation; Recruitment of NuMA to mitotic centrosomes Phagosome; Gap junction 17 High Q5FWX7 Oxysterol-binding protein OS=Mus musculus OX=10090 GN=Osbpl9 PE=1 SV=1 0 88.86 31 15 48 15 626 70.1 6.05 10 9 15 14 10 24 385821.5 52769367.25 39851148.94 113513985 1 13 11 14 Met-loss+Acetyl [N-Term] transport cytosol;endosome;Golgi;membrane Pf01237 100273 ENSMUSG00000028559.17 Osbpl9 4 0 High Q6P4T2 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Mus musculus OX=10090 GN=Snrnp200 PE=1 SV=1 0 97.683 19 26 47 26 2136 244.4 6.06 13 23 5 14 28 5 625037.125 31088575.59 68596855.31 23079914 1 14 16 8 cell differentiation;metabolic process membrane;nucleus;spliceosomal complex catalytic activity;DNA binding;nucleotide binding;protein binding;RNA binding "Pf00270, Pf00271, Pf02889, Pf04851" 320632 ENSMUSG00000003660.10 Snrnp200 2 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway Spliceosome 0 High Q9D0E1 Heterogeneous nuclear ribonucleoprotein M OS=Mus musculus OX=10090 GN=Hnrnpm PE=1 SV=3 0 60.969 31 20 47 20 729 77.6 8.63 2 15 14 7 2 19 18 8 7069274.25 100435213.5 101498162.8 76194100.75 11 17 16 16 metabolic process;regulation of biological process cell surface;membrane;nucleus;spliceosomal complex protein binding;RNA binding "Pf00076, Pf11532, Pf11608, Pf13893, Pf14259" 76936 ENSMUSG00000059208.14 Hnrnpm 17 mRNA Splicing - Major Pathway; FGFR2 alternative splicing Spliceosome 0 High A0A0B4J1H7 Immunoglobulin kappa variable 1-135 (Fragment) OS=Mus musculus OX=10090 GN=Igkv1-135 PE=4 SV=1 0 32.058 46 8 47 8 120 13.3 7.12 8 7 7 4 18 12 11 6 116198566.8 101469884 124701096 77625613.88 8 7 7 6 response to stimulus 243420 ENSMUSG00000096336.2 Igkv1-135 6 0 High P99024 Tubulin beta-5 chain OS=Mus musculus OX=10090 GN=Tubb5 PE=1 SV=1 0 83.25 61 21 46 4 444 49.6 4.89 3 2 5 21 5 2 5 34 1360184.969 23316555.5 2 3 cell organization and biogenesis cytoplasm;cytoskeleton;cytosol;membrane;nucleus catalytic activity;nucleotide binding;protein binding;structural molecule activity "Pf00091, Pf03953, Pf10644" 22154 ENSMUSG00000001525.10 Tubb5 17 Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Regulation of PLK1 Activity at G2/M Transition; Neutrophil degranulation; Recruitment of NuMA to mitotic centrosomes Phagosome; Gap junction 0 High Q8CC88 von Willebrand factor A domain-containing protein 8 OS=Mus musculus OX=10090 GN=Vwa8 PE=1 SV=2 0 85.968 19 28 46 28 1905 213.3 6.6 12 1 2 24 15 1 2 28 18613188.06 14176181.06 16566418.19 119218151.6 16 8 10 22 extracellular;mitochondrion catalytic activity;nucleotide binding "Pf00092, Pf07728, Pf13191, Pf13519, Pf13521" 219189 ENSMUSG00000058997.7 Vwa8 14 0 High Q922U2 "Keratin, type II cytoskeletal 5 OS=Mus musculus OX=10090 GN=Krt5 PE=1 SV=1" 0 40.23 21 18 45 10 580 61.7 7.75 9 9 4 11 13 12 6 14 235991792.1 303691080.1 270958160 1063104333 14 14 9 13 metabolic process cytoplasm;membrane;mitochondrion;nucleus catalytic activity;motor activity;protein binding;structural molecule activity "Pf00038, Pf01576, Pf03961, Pf04111, Pf05957" 110308 ENSMUSG00000061527.6 Krt5 15 Type I hemidesmosome assembly; Formation of the cornified envelope 8 High Q8BKZ9 "Pyruvate dehydrogenase protein X component, mitochondrial OS=Mus musculus OX=10090 GN=Pdhx PE=1 SV=1" 0 50.127 30 11 45 11 501 54 7.75 11 4 6 5 27 5 8 5 70937675.38 24527504.75 43943429.5 101547308.5 11 7 9 6 metabolic process mitochondrion;organelle lumen catalytic activity "Pf00198, Pf00364, Pf02817" 27402 ENSMUSG00000010914.10 Pdhx 2 Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Glyoxylate metabolism and glycine degradation Metabolic pathways 0 High Q9Z2Z6 Mitochondrial carnitine/acylcarnitine carrier protein OS=Mus musculus OX=10090 GN=Slc25a20 PE=1 SV=1 0 74.418 63 18 45 18 301 33 9.11 3 4 3 17 5 4 3 33 12555614.89 27324403.61 39394928 356287194 10 11 11 16 Met-loss+Acetyl [N-Term] transport cytosol;membrane;mitochondrion transporter activity Pf00153 57279 ENSMUSG00000032602.6 Slc25a20 9 Import of palmitoyl-CoA into the mitochondrial matrix 0 High Q9QWL7 "Keratin, type I cytoskeletal 17 OS=Mus musculus OX=10090 GN=Krt17 PE=1 SV=3" 0 30.027 20 11 45 2 433 48.1 5.06 5 11 3 5 11 17 6 11 101684902 194926297 114064936 302887491 2 4 1 3 cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytoskeleton catalytic activity;motor activity;protein binding;receptor activity;signal transducer activity;structural molecule activity "Pf00038, Pf01576, Pf07888" 16667 ENSMUSG00000035557.9 Krt17 11 Formation of the cornified envelope 3 High Q9DCD0 "6-phosphogluconate dehydrogenase, decarboxylating OS=Mus musculus OX=10090 GN=Pgd PE=1 SV=3" 0 113.151 51 22 44 22 483 53.2 7.23 22 44 529430.1719 722760885.1 2 22 metabolic process cytoplasm;nucleus catalytic activity;nucleotide binding "Pf00393, Pf03446" 110208 ENSMUSG00000028961.15 Pgd 4 Pentose phosphate pathway (hexose monophosphate shunt) Glutathione metabolism; Metabolic pathways; Pentose phosphate pathway; Carbon metabolism 0 High Q9JJZ4 Ubiquitin-conjugating enzyme E2 J1 OS=Mus musculus OX=10090 GN=Ube2j1 PE=1 SV=2 0 123.109 57 16 43 2 318 35 6.99 1 3 16 1 4 38 437773.5625 3925753.688 14465297.2 352241004 1 3 5 13 metabolic process;regulation of biological process cytoplasm;endoplasmic reticulum;membrane catalytic activity;nucleotide binding;protein binding Pf00179 56228 ENSMUSG00000028277.13 Ube2j1 4 Ubiquitin mediated proteolysis; Parkinson's disease; Protein processing in endoplasmic reticulum 11 High Q9DBG6 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Mus musculus OX=10090 GN=Rpn2 PE=1 SV=1 0 154.489 52 21 43 21 631 69 5.81 1 21 1 42 3893972.207 540514.4375 2943053.5 393306047.6 3 1 1 20 metabolic process;response to stimulus endoplasmic reticulum;membrane catalytic activity Pf05817 20014 ENSMUSG00000027642.15 Rpn2 2 Metabolic pathways; N-Glycan biosynthesis; Protein processing in endoplasmic reticulum 0 High G3UZ34 116 kDa U5 small nuclear ribonucleoprotein component OS=Mus musculus OX=10090 GN=Eftud2 PE=1 SV=1 0 75.683 27 19 43 18 962 108.3 5.02 14 16 7 15 21 7 1605938.563 50403409.06 92039495 46014022.39 4 14 14 10 catalytic activity;nucleotide binding "Pf00009, Pf00679, Pf03144, Pf03764, Pf14492" ENSMUSG00000020929.14 11 1 High Q6IFX2 "Keratin, type I cytoskeletal 42 OS=Mus musculus OX=10090 GN=Krt42 PE=1 SV=1" 0 30.491 29 12 43 5 452 50.1 5.16 6 10 3 5 11 16 7 9 110659161.4 174244762.5 76458824.13 205732166.8 10 9 5 8 cytoplasm structural molecule activity "Pf00038, Pf04156, Pf08317, Pf13166, Pf13514" 68239 ENSMUSG00000053654.7 Krt42 11 7 High P62869 Elongin-B OS=Mus musculus OX=10090 GN=Elob PE=1 SV=1 0 43.738 69 10 43 10 118 13.2 5.01 10 7 7 6 19 9 8 7 88086117.41 59522935.38 68340002 72511837.56 10 10 8 9 Acetyl [N-Term] metabolic process;regulation of biological process nucleus protein binding Pf00240 67673 ENSMUSG00000055839.5 Tceb2; Elob 17 RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Formation of RNA Pol II elongation complex ; Neddylation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Ubiquitin mediated proteolysis; HIF-1 signaling pathway; Pathways in cancer; Renal cell carcinoma 0 High J3QNW9 Kinesin-like protein KIF7 OS=Mus musculus OX=10090 GN=Kif7 PE=1 SV=1 0 7.427 2 1 42 1 1348 151.6 6.57 1 1 1 1 4 6 20 12 12661858895 7850213591 7402279933 7887659541 2 2 2 2 cellular component movement;regulation of biological process cytoplasm;cytoskeleton catalytic activity;motor activity;nucleotide binding;protein binding "Pf00225, Pf09726" 16576 ENSMUSG00000050382.14 Kif7 7 Hedgehog 'on' state; Hedgehog 'off' state Hedgehog signaling pathway 0 High Q9CZU6 "Citrate synthase, mitochondrial OS=Mus musculus OX=10090 GN=Cs PE=1 SV=1" 0 30.311 28 10 42 5 464 51.7 8.57 7 8 5 8 11 13 7 11 49701012.02 104086937 56115833 93606974.63 9 9 9 9 metabolic process mitochondrion;nucleus;organelle lumen catalytic activity;RNA binding Pf00285 12974 ENSMUSG00000005683.8 Cs 10 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Biosynthesis of amino acids; 2-Oxocarboxylic acid metabolism; Carbon metabolism; Glyoxylate and dicarboxylate metabolism 5 High Q61414 "Keratin, type I cytoskeletal 15 OS=Mus musculus OX=10090 GN=Krt15 PE=1 SV=2" 0 18.21 13 7 42 1 452 49.1 4.86 5 7 4 4 11 13 8 10 19285744 1 nucleus protein binding;structural molecule activity "Pf00038, Pf12128, Pf13514" 16665 Krt15 11 0 High Q91VT8 Small integral membrane protein 14 OS=Mus musculus OX=10090 GN=Smim14 PE=1 SV=1 0 67.204 100 5 42 5 99 10.7 5.73 3 4 5 4 6 32 17035799 38436747.5 1100494939 4 4 6 Met-loss [N-Term]; Met-loss+Acetyl [N-Term] endoplasmic reticulum;membrane Pf11027 68552 ENSMUSG00000037822.12 1110003E01Rik; Smim14 5 0 High P01027 Complement C3 OS=Mus musculus OX=10090 GN=C3 PE=1 SV=3 0 82.114 16 22 42 22 1663 186.4 6.73 17 3 9 5 24 3 10 5 46148379.84 24803709.25 37025827.75 35725717.75 19 9 12 11 cell organization and biogenesis;coagulation;defense response;metabolic process;regulation of biological process;response to stimulus extracellular enzyme regulator activity;protein binding "Pf00207, Pf01759, Pf01821, Pf01835, Pf07677, Pf07678, Pf07703, Pf10569, Pf11974" 12266 ENSMUSG00000024164.15 C3 17 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Regulation of Complement cascade; Peptide ligand-binding receptors; G alpha (i) signalling events; Activation of C3 and C5; Post-translational protein phosphorylation; Alternative complement activation; Neutrophil degranulation; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Herpes simplex infection; Chagas disease (American trypanosomiasis); Staphylococcus aureus infection; Tuberculosis; Phagosome; Complement and coagulation cascades; Pertussis; Legionellosis; Systemic lupus erythematosus; Leishmaniasis; Viral carcinogenesis 0 High Q61810 Latent-transforming growth factor beta-binding protein 3 OS=Mus musculus OX=10090 GN=Ltbp3 PE=1 SV=4 0 147.227 32 26 42 21 1253 134.3 6.18 26 42 1221537.672 237466253.5 2 19 3 High A0A0B4J1I0 Immunoglobulin kappa variable 1-110 (Fragment) OS=Mus musculus OX=10090 GN=Igkv1-110 PE=4 SV=5 0 35.012 39 4 42 1 119 13.1 8.91 4 3 3 3 16 8 11 7 322829588.6 194451671 421839697.5 215216591 5 4 5 3 response to stimulus Pf07686 628261; 381777 ENSMUSG00000093861.2 Bb1; Igkv1-110 6 3 High Q99PV0 Pre-mRNA-processing-splicing factor 8 OS=Mus musculus OX=10090 GN=Prpf8 PE=1 SV=2 0 89.248 14 26 40 26 2335 273.4 8.84 11 23 3 12 25 3 68703.40625 35613014.19 89240249.06 32772334 1 15 16 9 cell organization and biogenesis;metabolic process;response to stimulus membrane;nucleus;spliceosomal complex catalytic activity;protein binding;RNA binding "Pf01398, Pf08082, Pf08083, Pf08084, Pf10596, Pf10597, Pf10598, Pf12134" 192159 ENSMUSG00000020850.14 Prpf8 11 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway Spliceosome 0 High A0A140T8M0 Immunoglobulin kappa variable 1-117 (Fragment) OS=Mus musculus OX=10090 GN=Igkv1-117 PE=4 SV=2 0 32.858 39 4 40 1 119 13.1 8.48 4 3 3 3 13 7 13 7 18558950 7673996.5 31722006.5 15726735 2 1 2 1 "Pf07679, Pf07686" 16098 ENSMUSG00000094335.2 Igkv1-117 6 0 High P25444 40S ribosomal protein S2 OS=Mus musculus OX=10090 GN=Rps2 PE=1 SV=3 0 35.315 45 13 40 13 293 31.2 10.24 6 9 6 11 7 12 8 13 26435392 97389174.25 76270245 143022263 11 11 10 11 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity "Pf00333, Pf03719" 16898; 546298 ENSMUSG00000044533.15 Rps2; Rps2-ps13 17; X Ribosome 0 High P97351 40S ribosomal protein S3a OS=Mus musculus OX=10090 GN=Rps3a PE=1 SV=3 0 36.446 42 12 40 12 264 29.9 9.73 5 6 7 9 8 8 10 14 11927936.94 46720046.13 64645619 87042915.25 9 10 11 11 cell differentiation;metabolic process;regulation of biological process cytoplasm;cytosol;endoplasmic reticulum;nucleus;ribosome protein binding;RNA binding;structural molecule activity Pf01015 20091 ENSMUSG00000028081.6 Rps3a; Rps3a1 3 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High F6SPK0 Ubiquitin-conjugating enzyme E2 J1 (Fragment) OS=Mus musculus OX=10090 GN=Ube2j1 PE=1 SV=1 0 102.055 62 15 40 1 262 28.9 7.25 1 2 15 1 3 36 metabolic process;regulation of biological process membrane Pf00179 ENSMUSG00000028277.13 4 0 High P83940 Elongin-C OS=Mus musculus OX=10090 GN=Eloc PE=1 SV=1 0 40.084 66 7 39 7 112 12.5 4.78 7 4 6 4 16 7 9 7 74518939.25 49772771.75 62621819.25 56467932.25 7 6 7 6 metabolic process;regulation of biological process nucleus catalytic activity;protein binding Pf03931 67923; 102642819 ENSMUSG00000079658.9 Tceb1; Eloc; LOC101056616; LOC102642819 1; 2 RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Formation of RNA Pol II elongation complex ; Interleukin-7 signaling; Neddylation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Ubiquitin mediated proteolysis; HIF-1 signaling pathway; Pathways in cancer; Renal cell carcinoma 0 High P12970 60S ribosomal protein L7a OS=Mus musculus OX=10090 GN=Rpl7a PE=1 SV=2 0 31.096 37 11 39 11 266 30 10.56 4 8 9 7 5 12 11 11 12292136.8 59401219.25 46491955 84840822 8 9 9 9 metabolic process cytoplasm;membrane;nucleus;ribosome protein binding;RNA binding Pf01248 27176 ENSMUSG00000062647.16 Rpl7a 2 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q9R045 Angiopoietin-related protein 2 OS=Mus musculus OX=10090 GN=Angptl2 PE=2 SV=2 0 87.854 44 18 38 18 493 57.1 7.75 16 2 3 8 23 2 3 10 60191484.5 29423189.75 18277321.63 49674162.25 14 11 6 11 extracellular Pf00147 26360 ENSMUSG00000004105.8 Angptl2 2 0 High Q922Q4 Pyrroline-5-carboxylate reductase 2 OS=Mus musculus OX=10090 GN=Pycr2 PE=1 SV=1 0 52.393 51 13 38 13 320 33.6 7.77 1 7 11 10 1 8 16 13 9733593.344 67874024.38 119596618 170193771.5 6 10 12 12 Met-loss+Acetyl [N-Term] metabolic process;response to stimulus cytoplasm;mitochondrion catalytic activity;nucleotide binding "Pf01210, Pf03807, Pf10727, Pf14748" 69051 ENSMUSG00000026520.8 Pycr2 1 Amino acid synthesis and interconversion (transamination) Arginine and proline metabolism; Metabolic pathways; Biosynthesis of amino acids 0 High G5E902 "Phosphate carrier protein, mitochondrial OS=Mus musculus OX=10090 GN=Slc25a3 PE=1 SV=1" 0 49.911 31 13 38 13 358 39.7 9.29 1 1 3 13 1 2 3 32 4792263.672 17407867.63 22956420.63 489976911.1 5 6 7 15 transport membrane;mitochondrion protein binding;transporter activity Pf00153 18674 ENSMUSG00000061904.12 Slc25a3 10 0 High Q80X19 Collagen alpha-1(XIV) chain OS=Mus musculus OX=10090 GN=Col14a1 PE=1 SV=2 0 72.824 15 19 38 19 1797 192.9 5.1 18 4 5 3 24 6 5 3 44644201.47 23315548.78 30829095.63 23514620.38 17 9 10 7 cell organization and biogenesis;regulation of biological process extracellular protein binding;RNA binding "Pf00041, Pf00092, Pf01391, Pf13519" 12818 ENSMUSG00000022371.15 Col14a1 15 Collagen chain trimerization; Assembly of collagen fibrils and other multimeric structures 0 High Q8BH64 EH domain-containing protein 2 OS=Mus musculus OX=10090 GN=Ehd2 PE=1 SV=1 0 61.554 28 14 38 13 543 61.1 6.51 9 4 2 13 14 4 2 18 20052260.78 25017737.13 25831173.13 115081581.5 12 10 9 13 cell organization and biogenesis;regulation of biological process;transport cytoplasm;cytoskeleton;cytosol;endosome;membrane catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00350, Pf01926, Pf12763" 259300 ENSMUSG00000074364.6 Ehd2 7 Factors involved in megakaryocyte development and platelet production Endocytosis 1 High Q8CI95 Oxysterol-binding protein-related protein 11 OS=Mus musculus OX=10090 GN=Osbpl11 PE=1 SV=2 0 107.223 36 19 37 19 751 83.6 7.01 10 5 14 10 5 22 11870494.39 69890891.5 55214249 156613569.5 3 13 12 13 cell differentiation;regulation of biological process;transport endosome;Golgi;membrane "Pf00169, Pf01237, Pf15409" 106326 Osbpl11 16 0 High P70333 Heterogeneous nuclear ribonucleoprotein H2 OS=Mus musculus OX=10090 GN=Hnrnph2 PE=1 SV=1 0 39.728 33 11 37 2 449 49.2 6.3 10 5 5 5 18 6 7 6 cytosol;membrane;nucleus RNA binding "Pf00076, Pf08080, Pf14259" 56258 ENSMUSG00000045427.13 Hnrnph2 X mRNA Splicing - Major Pathway 0 High Q9D6F9 Tubulin beta-4A chain OS=Mus musculus OX=10090 GN=Tubb4a PE=1 SV=3 0 82.249 58 18 37 1 444 49.6 4.88 2 1 4 18 4 1 4 28 2550735.25 11635307 1 1 cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton;nucleus catalytic activity;metal ion binding;nucleotide binding;structural molecule activity "Pf00091, Pf03953, Pf10644" 22153 ENSMUSG00000062591.5 Tubb4a 17 Anchoring of the basal body to the plasma membrane; Intraflagellar transport; Hedgehog 'on' state; AURKA Activation by TPX2; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Hedgehog 'off' state; Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes Phagosome; Gap junction 0 High P35564 Calnexin OS=Mus musculus OX=10090 GN=Canx PE=1 SV=1 0 97.714 40 22 37 22 591 67.2 4.64 22 37 1557913.906 1777999 389182236 3 1 20 metabolic process;transport cytoplasm;endoplasmic reticulum;membrane;ribosome metal ion binding;protein binding;RNA binding Pf00262 12330 ENSMUSG00000020368.15 Canx 11 "Calnexin/calreticulin cycle; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; MHC class II antigen presentation; Interleukin-35 Signalling" HTLV-I infection; Thyroid hormone synthesis; Phagosome; Antigen processing and presentation; Protein processing in endoplasmic reticulum 0 High Q9JKR6 Hypoxia up-regulated protein 1 OS=Mus musculus OX=10090 GN=Hyou1 PE=1 SV=1 0 102.779 31 24 37 24 999 111.1 5.19 1 24 1 36 268020064 294597716 264421753.9 492744996.3 1 3 3 20 regulation of biological process;response to stimulus;transport endoplasmic reticulum;extracellular;membrane;organelle lumen nucleotide binding Pf00012 12282 ENSMUSG00000032115.14 Hyou1 9 Protein processing in endoplasmic reticulum 0 High P12382 "ATP-dependent 6-phosphofructokinase, liver type OS=Mus musculus OX=10090 GN=Pfkl PE=1 SV=4" 0 117.779 42 21 37 18 780 85.3 7.17 6 1 20 6 1 30 10087981.14 5288331.875 5423120.5 185322429.3 10 4 3 16 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane catalytic activity;metal ion binding;nucleotide binding;protein binding Pf00365 18641 ENSMUSG00000020277.10 Pfkl 10 Neutrophil degranulation; Glycolysis RNA degradation; Metabolic pathways; Biosynthesis of amino acids; Glycolysis / Gluconeogenesis; Pentose phosphate pathway; HIF-1 signaling pathway; AMPK signaling pathway; Carbon metabolism; Fructose and mannose metabolism; Galactose metabolism; Central carbon metabolism in cancer; Glucagon signaling pathway 3 High Q9QWK4 CD5 antigen-like OS=Mus musculus OX=10090 GN=Cd5l PE=1 SV=3 0 47.286 38 12 37 12 352 38.8 5.16 11 4 7 4 21 4 8 4 87994220.63 30580359.38 50479158.25 31264523.5 12 10 12 8 cell death;defense response;response to stimulus;transport cytoplasm;extracellular;membrane receptor activity "Pf00530, Pf15494" 11801 ENSMUSG00000015854.7 Cd5l 3 0 High A0A1L1SQU7 FAT atypical cadherin 1 OS=Mus musculus OX=10090 GN=Fat1 PE=1 SV=1 0 79.273 7 23 37 23 4645 511.9 5 17 7 11 18 7 12 1681049.906 54889941.5 53671466.88 45029759.5 5 13 14 10 cell organization and biogenesis cell surface;membrane;nucleus metal ion binding;protein binding "Pf00008, Pf00028, Pf00054, Pf02210, Pf05444, Pf06247, Pf07645, Pf07974, Pf12785, Pf12947" 14107 ENSMUSG00000070047.14 Fat1 8 0 High A0A075B5Q3 Immunoglobulin heavy variable 2-5 OS=Mus musculus OX=10090 GN=Ighv2-5 PE=4 SV=1 0 25.113 39 4 37 3 115 12.5 8.97 4 4 4 2 18 8 8 3 148527475.7 73272999.5 140406821 40533674.75 6 4 4 3 ENSMUSG00000096498.3 12 1 High Q61781 "Keratin, type I cytoskeletal 14 OS=Mus musculus OX=10090 GN=Krt14 PE=1 SV=2" 0 34.726 22 11 37 1 484 52.8 5.17 5 10 3 3 9 16 6 6 30756284 3019588.5 2 1 cell differentiation;cell organization and biogenesis;response to stimulus cytoplasm;nucleus protein binding;structural molecule activity "Pf00038, Pf13514" 16664 ENSMUSG00000045545.8 Krt14 11 Type I hemidesmosome assembly; Formation of the cornified envelope 1 High Q6P9N1 Hyccin OS=Mus musculus OX=10090 GN=Fam126a PE=1 SV=3 0 51.085 29 11 36 5 521 57.3 7.88 7 11 7 8 17 11 1297498.109 52015209.75 106527624.8 96002973 4 8 9 9 cell organization and biogenesis;metabolic process cytoplasm;cytosol;membrane Pf09790 84652 ENSMUSG00000028995.14 Fam126a 5 6 High Q9D0M3 "Cytochrome c1, heme protein, mitochondrial OS=Mus musculus OX=10090 GN=Cyc1 PE=1 SV=1" 0 74.764 58 12 36 12 325 35.3 9.16 6 3 4 12 7 4 4 21 53668565.3 58900210.19 61983805.88 183397185.5 8 6 5 11 metabolic process;response to stimulus;transport membrane;mitochondrion;nucleus metal ion binding;protein binding Pf02167 66445 ENSMUSG00000022551.7 Cyc1 15 Respiratory electron transport Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 High Q6DFZ1 Golgi-specific brefeldin A-resistance factor 1 OS=Mus musculus OX=10090 GN=Gbf1 PE=1 SV=1 0 87.197 17 21 36 21 1861 206.7 5.8 10 5 18 10 5 21 1240827.25 30786051.66 25289937 64360652.5 2 11 9 11 cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport cytosol;Golgi;membrane;mitochondrion;organelle lumen protein binding "Pf01369, Pf12783" 107338 ENSMUSG00000025224.14 Gbf1 19 Clathrin derived vesicle budding; VxPx cargo-targeting to cilium; COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic Endocytosis 0 High Q8K019 Bcl-2-associated transcription factor 1 OS=Mus musculus OX=10090 GN=Bclaf1 PE=1 SV=2 0 43.226 17 14 36 13 919 105.9 9.99 8 11 7 11 16 9 1000941.688 58816350.5 109373699.5 54358925 1 10 10 8 cell death;metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus DNA binding;protein binding;RNA binding Pf15440 72567 ENSMUSG00000037608.16 Bclaf1 10 0 High P84104 Serine/arginine-rich splicing factor 3 OS=Mus musculus OX=10090 GN=Srsf3 PE=1 SV=1 0 37.429 43 7 35 7 164 19.3 11.65 2 4 6 6 3 7 15 10 21941802.69 56035443.75 137859729.4 74140452.75 4 6 6 6 metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;nucleus protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 20383 ENSMUSG00000071172.12 Srsf3 17 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript Herpes simplex infection; Spliceosome 0 High P10493 Nidogen-1 OS=Mus musculus OX=10090 GN=Nid1 PE=1 SV=2 0 75.671 22 19 35 19 1245 136.5 5.44 19 1 1 1 32 1 1 1 55248830.59 8189394.875 12696473.38 1992813.125 19 3 5 1 cell organization and biogenesis;regulation of biological process cell surface;extracellular;membrane metal ion binding;protein binding "Pf00008, Pf00058, Pf00086, Pf06119, Pf06247, Pf07474, Pf07645, Pf12662, Pf12947, Pf14670" 18073 ENSMUSG00000005397.7 Nid1 13 Laminin interactions; Degradation of the extracellular matrix 0 High A0A0G2JE99 Immunoglobulin lambda constant 1 (Fragment) OS=Mus musculus OX=10090 GN=Iglc1 PE=4 SV=1 0 63.17 80 5 35 5 106 11.7 6.27 5 3 4 3 16 6 9 4 70319935.84 59574668 105709755.5 29356581 5 4 4 3 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding "Pf07654, Pf13927" ENSMUSG00000105906.1 16 Cell surface interactions at the vascular wall 0 High Q9Z0X1 "Apoptosis-inducing factor 1, mitochondrial OS=Mus musculus OX=10090 GN=Aifm1 PE=1 SV=1" 0 54.691 30 14 35 14 612 66.7 9.17 5 2 6 14 7 2 7 19 20483628.38 18723248.75 40206206 136099008.6 7 7 9 10 cell death;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;DNA binding;nucleotide binding;protein binding "Pf00070, Pf07992, Pf14721, Pf14962" 26926 ENSMUSG00000036932.14 Aifm1 X Apoptosis 0 High P11087 Collagen alpha-1(I) chain OS=Mus musculus OX=10090 GN=Col1a1 PE=1 SV=4 0 25.475 5 7 35 7 1453 137.9 5.85 7 6 5 4 14 8 8 5 62221164.63 47549920.63 52506935.75 34129286.25 8 7 7 6 cell communication;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;extracellular;Golgi metal ion binding;protein binding;structural molecule activity "Pf00093, Pf01391, Pf01410" 12842 ENSMUSG00000001506.10 Col1a1 11 Anchoring fibril formation; ECM proteoglycans; Cell surface interactions at the vascular wall; Platelet Aggregation (Plug Formation); Integrin cell surface interactions; Collagen degradation; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; Crosslinking of collagen fibrils; Collagen chain trimerization; GP1b-IX-V activation signalling; Platelet Adhesion to exposed collagen; MET activates PTK2 signaling; GPVI-mediated activation cascade; Non-integrin membrane-ECM interactions AGE-RAGE signaling pathway in diabetic complications; Focal adhesion; Protein digestion and absorption; Platelet activation; Proteoglycans in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway; Amoebiasis 0 High P43406 Integrin alpha-V OS=Mus musculus OX=10090 GN=Itgav PE=1 SV=2 0 92.535 30 25 34 25 1044 115.3 5.63 25 34 11224634.19 6621024.836 9897256 189315863 4 2 2 19 cell differentiation;cell growth;cell organization and biogenesis;cellular component movement;cellular homeostasis;defense response;development;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytosol;membrane;nucleus metal ion binding;protein binding;transporter activity "Pf01839, Pf08441, Pf13517" 16410 ENSMUSG00000027087.11 Itgav 2 ECM proteoglycans; Molecules associated with elastic fibres; Cross-presentation of particulate exogenous antigens (phagosomes); Integrin cell surface interactions; VEGFA-VEGFR2 Pathway; Neutrophil degranulation; Signal transduction by L1; Syndecan interactions Hypertrophic cardiomyopathy (HCM); Regulation of actin cytoskeleton; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Focal adhesion; Small cell lung cancer; Dilated cardiomyopathy; Cell adhesion molecules (CAMs); Phagosome; Proteoglycans in cancer; Thyroid hormone signaling pathway; Pathways in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway 0 High O35206 Collagen alpha-1(XV) chain OS=Mus musculus OX=10090 GN=Col15a1 PE=1 SV=2 0 51.825 10 11 34 11 1367 140.4 4.89 11 4 3 2 24 4 4 2 83020614.5 32196011.75 40713131 22475589.25 11 8 7 6 extracellular structural molecule activity "Pf01391, Pf06482, Pf13385" 12819 ENSMUSG00000028339.17 Col15a1 4 Collagen chain trimerization; Collagen degradation Protein digestion and absorption 0 High P62908 40S ribosomal protein S3 OS=Mus musculus OX=10090 GN=Rps3 PE=1 SV=1 0 36.326 48 12 34 12 243 26.7 9.66 3 4 7 11 4 6 9 15 6438513.188 48084119.63 54780627.63 95845337 6 9 10 10 cell death;cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;endoplasmic reticulum;membrane;mitochondrion;nucleus;organelle lumen;ribosome catalytic activity;DNA binding;protein binding;RNA binding;structural molecule activity "Pf00189, Pf07650" 27050 ENSMUSG00000030744.13 Rps3 7 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High O54988 STE20-like serine/threonine-protein kinase OS=Mus musculus OX=10090 GN=Slk PE=1 SV=2 0.007 1.905 1 1 34 1 1233 141.4 5.14 1 1 1 1 15 6 10 3 2657919991 2371260105 2380937700 1509946499 1 1 1 1 cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm catalytic activity;nucleotide binding;protein binding "Pf00069, Pf07714, Pf12474, Pf14531" 20874 ENSMUSG00000025060.14 Slk 19 Oocyte meiosis 0 High O54734 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Mus musculus OX=10090 GN=Ddost PE=1 SV=2 0 100.732 57 16 34 16 441 49 5.83 16 34 322831399.3 15 metabolic process;response to stimulus endoplasmic reticulum;membrane catalytic activity Pf03345 13200 ENSMUSG00000028757.4 Ddost 4 Neutrophil degranulation Metabolic pathways; N-Glycan biosynthesis; Protein processing in endoplasmic reticulum 0 High Q9CQR4 Acyl-coenzyme A thioesterase 13 OS=Mus musculus OX=10090 GN=Acot13 PE=1 SV=1 0 31.433 74 8 33 8 140 15.2 8.82 8 6 4 2 16 8 6 3 145698735.9 79419306.25 77423483.75 55756986.5 8 7 6 5 Met-loss+Acetyl [N-Term] cell organization and biogenesis cytoplasm;cytoskeleton;cytosol;mitochondrion;nucleus catalytic activity Pf03061 66834 ENSMUSG00000006717.6 Acot13 13 Mitochondrial Fatty Acid Beta-Oxidation 0 High P46978 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Mus musculus OX=10090 GN=Stt3a PE=1 SV=1 0 65.332 25 18 33 17 705 80.5 8.1 18 33 1334677.875 4934397 386549196.5 1 1 17 metabolic process endoplasmic reticulum;membrane catalytic activity;metal ion binding Pf02516 16430 ENSMUSG00000032116.18 Stt3a 9 Metabolic pathways; N-Glycan biosynthesis; Protein processing in endoplasmic reticulum 0 High E9Q4Z2 Acetyl-CoA carboxylase 2 OS=Mus musculus OX=10090 GN=Acacb PE=1 SV=1 0 54.71 7 14 33 8 2448 275.6 6.32 12 1 4 10 14 1 5 13 3845490.539 322976.0625 15729707.75 6 1 6 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00289, Pf00364, Pf01039, Pf02785, Pf02786, Pf08326, Pf13535, Pf15632" 100705 ENSMUSG00000042010.16 Acacb 5 ChREBP activates metabolic gene expression; Biotin transport and metabolism; Import of palmitoyl-CoA into the mitochondrial matrix Pyruvate metabolism; Insulin signaling pathway; Metabolic pathways; Insulin resistance; Propanoate metabolism; Adipocytokine signaling pathway; AMPK signaling pathway; Fatty acid biosynthesis; Glucagon signaling pathway 0 High P62270 40S ribosomal protein S18 OS=Mus musculus OX=10090 GN=Rps18 PE=1 SV=3 0 30.345 51 10 33 10 152 17.7 10.99 6 8 6 7 7 10 7 9 18738652.44 49723735.25 45742974.38 91840953.63 9 10 10 10 metabolic process cytoplasm;cytosol;membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity Pf00416 20084 ENSMUSG00000008668.14 Rps18 17 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High Q63918 Caveolae-associated protein 2 OS=Mus musculus OX=10090 GN=Cavin2 PE=1 SV=3 0 45.999 35 12 33 12 418 46.7 5.21 4 6 11 6 6 7 13 7 18459260.5 49425042.5 77563672.25 54865543.75 9 9 9 7 cell organization and biogenesis;regulation of biological process cytoplasm;cytosol;membrane protein binding Pf15237 20324 ENSMUSG00000045954.7 Sdpr; Cavin2 1 0 High Q99JR5 Tubulointerstitial nephritis antigen-like OS=Mus musculus OX=10090 GN=Tinagl1 PE=1 SV=1 0 80.116 42 11 33 11 466 52.6 6.77 10 7 5 2 18 8 5 2 54898303.44 33274048.5 20090646 14056524 11 7 5 4 metabolic process;response to stimulus;transport cytoplasm;extracellular;vacuole catalytic activity;protein binding;receptor activity "Pf00112, Pf01033" 94242 ENSMUSG00000028776.14 Tinagl1 4 0 High P47738 "Aldehyde dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Aldh2 PE=1 SV=1" 0 57.29 33 13 33 12 519 56.5 7.62 11 2 4 7 19 3 4 7 27950063 20387393.13 35325773.75 52933777.75 12 7 10 9 metabolic process;regulation of biological process mitochondrion;organelle lumen catalytic activity;nucleotide binding;protein binding Pf00171 11669 ENSMUSG00000029455.14 Aldh2 5 Metabolism of serotonin; Ethanol oxidation "Histidine metabolism; Pyruvate metabolism; Arginine and proline metabolism; Tryptophan metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Lysine degradation; Fatty acid degradation; Glycolysis / Gluconeogenesis; beta-Alanine metabolism; Ascorbate and aldarate metabolism; Glycerolipid metabolism; Pentose and glucuronate interconversions" 1 High Q60715 Prolyl 4-hydroxylase subunit alpha-1 OS=Mus musculus OX=10090 GN=P4ha1 PE=1 SV=2 0 94.338 46 19 33 5 534 60.9 5.9 19 33 13258423.81 10420541.75 10095262.25 260100257.8 4 2 2 16 cell organization and biogenesis;metabolic process endoplasmic reticulum;membrane;mitochondrion;organelle lumen catalytic activity;metal ion binding;protein binding "Pf03171, Pf08336" 18451 ENSMUSG00000019916.14 P4ha1 10 Collagen biosynthesis and modifying enzymes Arginine and proline metabolism; Metabolic pathways 13 High Q8R2R1 Protein O-mannosyl-transferase 1 OS=Mus musculus OX=10090 GN=Pomt1 PE=1 SV=1 0 82.514 25 13 33 13 746 85.2 8.29 13 33 358249.4063 3215090.5 7968126 206260589 1 1 2 11 cell organization and biogenesis;metabolic process;response to stimulus endoplasmic reticulum;membrane catalytic activity "Pf02366, Pf02815, Pf13231" 99011 ENSMUSG00000039254.16 Pomt1 2 O-linked glycosylation Other types of O-glycan biosynthesis 0 High A0A140T8Q3 Immunoglobulin kappa variable 6-17 (Fragment) OS=Mus musculus OX=10090 GN=Igkv6-17 PE=1 SV=2 0 20.268 40 4 33 1 115 12.8 5.81 4 4 4 4 11 6 9 7 14260917.75 7851379 14877675 9253522 1 1 1 1 response to stimulus Pf07686 667865 ENSMUSG00000095794.2 Igkv6-17 6 0 High Q64475 Histone H2B type 1-B OS=Mus musculus OX=10090 GN=H2bc3 PE=1 SV=3 0 21.31 52 7 33 7 126 13.9 10.32 6 6 5 6 11 6 8 8 74393201.41 46876038.92 75599403.5 88536571 6 6 6 7 cell organization and biogenesis chromosome;cytosol;nucleus DNA binding;protein binding "Pf00125, Pf00808" 319178 ENSMUSG00000075031.3 Hist1h2bb 13 HATs acetylate histones; E3 ubiquitin ligases ubiquitinate target proteins; Meiotic Recombination; Mus musculus biological processes; NoRC negatively regulates rRNA expression; Meiotic Synapsis Alcoholism; Systemic lupus erythematosus; Viral carcinogenesis 0 High Q91VC3 Eukaryotic initiation factor 4A-III OS=Mus musculus OX=10090 GN=Eif4a3 PE=1 SV=3 0 64.393 45 16 33 15 411 46.8 6.73 1 7 16 2 3 7 21 2 3249580.281 48184641.61 117012451 48772188 4 14 14 10 Met-loss+Acetyl [N-Term] metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;membrane;nucleus;spliceosomal complex catalytic activity;nucleotide binding;RNA binding "Pf00270, Pf00271" 192170 ENSMUSG00000025580.15 Eif4a3 11 mRNA 3'-end processing; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Cleavage of Growing Transcript in the Termination Region ; mRNA Splicing - Major Pathway; ISG15 antiviral mechanism; Transport of Mature mRNA derived from an Intron-Containing Transcript; Deadenylation of mRNA mRNA surveillance pathway; Spliceosome; RNA transport 1 High P01592 Immunoglobulin J chain OS=Mus musculus OX=10090 GN=Jchain PE=1 SV=4 0 24.031 28 5 33 5 159 18 4.89 5 5 3 2 15 9 6 3 68645471.75 51540398.75 44257521.75 32441823 5 5 5 5 defense response;regulation of biological process;response to stimulus extracellular DNA binding;protein binding Pf15097 16069 ENSMUSG00000067149.6 Igj; Jchain 5 Cell surface interactions at the vascular wall; Scavenging of heme from plasma 0 High Q8BGH2 Sorting and assembly machinery component 50 homolog OS=Mus musculus OX=10090 GN=Samm50 PE=1 SV=1 0 48.464 29 13 33 13 469 51.8 6.8 11 1 1 11 14 1 1 17 22311299.25 8565021.75 17173887.75 96354599.75 11 3 5 11 cell organization and biogenesis;transport cytoplasm;membrane;mitochondrion protein binding "Pf01103, Pf07244" 68653 ENSMUSG00000022437.6 Samm50 15 0 High P05213 Tubulin alpha-1B chain OS=Mus musculus OX=10090 GN=Tuba1b PE=1 SV=2 0 84.17 36 15 33 3 451 50.1 5.06 6 1 1 14 6 2 1 24 10168267.94 15901646.63 20363972.88 183956392 9 6 7 14 cell organization and biogenesis;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane catalytic activity;nucleotide binding;protein binding;RNA binding;structural molecule activity "Pf00091, Pf03953" 22143 ENSMUSG00000023004.8 Tuba1b 15 Intraflagellar transport; Hedgehog 'on' state; Hedgehog 'off' state Phagosome; Gap junction; Apoptosis 11 High A0A0R4J0D3 Dolichyl-diphosphooligosaccharide--protein glycotransferase OS=Mus musculus OX=10090 GN=Stt3b PE=1 SV=1 0 54.273 21 18 32 17 823 93.3 9 18 32 937478.7813 2999771.25 2328683.25 321600961.5 2 1 1 13 Met-loss+Acetyl [N-Term] metabolic process;response to stimulus endoplasmic reticulum;membrane catalytic activity;metal ion binding "Pf02516, Pf13231" 68292 ENSMUSG00000032437.10 Stt3b 9 Metabolic pathways; N-Glycan biosynthesis; Protein processing in endoplasmic reticulum 1 High A0A0G2JFA8 Immunoglobulin kappa variable 17-121 (Fragment) OS=Mus musculus OX=10090 GN=Igkv17-121 PE=4 SV=4 0 26.658 33 2 32 2 117 12.9 4.36 2 2 2 2 13 4 8 7 122684696.6 118909176.8 170183396.5 73076637 4 3 3 2 response to stimulus "Pf00047, Pf07686" 667435 ENSMUSG00000076514.3 Igkv17-121 6 0 High A0A075B5N4 Immunoglobulin kappa chain variable 8-27 OS=Mus musculus OX=10090 GN=Igkv8-27 PE=4 SV=1 0 34.592 61 5 32 2 100 11 7.96 5 5 5 2 9 9 9 5 12859291.94 32247955 15491852 2438871.75 3 3 2 1 Pf07686 ENSMUSG00000076580.3 6 0 High Q6GSS7 Histone H2A type 2-A OS=Mus musculus OX=10090 GN=Hist2h2aa1 PE=1 SV=3 0 18.42 46 6 32 2 130 14.1 10.9 5 4 4 4 12 7 7 6 67316907 36254524.99 50445585.57 35972684.48 5 5 5 5 cell organization and biogenesis;regulation of biological process chromosome;nucleus DNA binding;protein binding "Pf00125, Pf00808" 319192; 15267 ENSMUSG00000063954.7; ENSMUSG00000064220.6 Hist2h2aa2; Hist2h2aa1 3 RMTs methylate histone arginines; Meiotic Recombination; Mus musculus biological processes; Ub-specific processing proteases; NoRC negatively regulates rRNA expression; UCH proteinases; Metalloprotease DUBs; Meiotic Synapsis Alcoholism; Systemic lupus erythematosus 4 High O70325 Phospholipid hydroperoxide glutathione peroxidase OS=Mus musculus OX=10090 GN=Gpx4 PE=1 SV=4 0 42.401 56 12 32 12 197 22.2 8.46 6 3 6 9 8 3 6 15 19597152.97 38277089.13 59601150 138560769.8 12 10 12 12 cell organization and biogenesis;development;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus antioxidant activity;catalytic activity;protein binding Pf00255 625249 ENSMUSG00000075706.10 Gpx4 10 Synthesis of 12-eicosatetraenoic acid derivatives; Synthesis of 15-eicosatetraenoic acid derivatives Glutathione metabolism 0 High A0A140T8M5 Immunoglobulin kappa variable 6-15 (Fragment) OS=Mus musculus OX=10090 GN=Igkv6-15 PE=1 SV=2 0 19.463 40 4 32 3 115 12.7 4.96 4 4 4 3 12 6 7 7 77499751.75 61629749 84248818 84160354.88 3 3 3 3 "Pf00047, Pf07679, Pf07686" 108022 ENSMUSG00000094797.1 Igkv6-15 6 0 High F8VQJ3 Laminin subunit gamma-1 OS=Mus musculus OX=10090 GN=Lamc1 PE=1 SV=1 0 98.247 23 22 31 22 1607 177.1 5.19 22 31 49909595.19 5233464.875 6269554.5 6691728.375 20 4 4 3 cell organization and biogenesis;cellular component movement;regulation of biological process cytoskeleton;extracellular catalytic activity;motor activity;protein binding;structural molecule activity "Pf00052, Pf00053, Pf00055, Pf00261, Pf01576, Pf04012, Pf05262, Pf05483, Pf05557, Pf05701, Pf06008, Pf06160, Pf08317, Pf10174, Pf12795, Pf13514, Pf13868, Pf13949" 226519 ENSMUSG00000026478.14 Lamc1 1 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); MET activates PTK2 signaling; Laminin interactions; Post-translational protein phosphorylation Focal adhesion; Toxoplasmosis; Small cell lung cancer; Pathways in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway; Prion diseases; Amoebiasis 0 High A0A140T8M3 Immunoglobulin kappa chain variable 8-30 (Fragment) OS=Mus musculus OX=10090 GN=Igkv8-30 PE=4 SV=2 0 22.274 50 6 31 3 121 13.3 6.49 6 6 4 2 12 8 6 5 85124891 83989638.75 116057514 65032113.64 6 6 6 6 Pf07686 384419 ENSMUSG00000076577.2 Igkv8-30 6 3 High P62281 40S ribosomal protein S11 OS=Mus musculus OX=10090 GN=Rps11 PE=1 SV=3 0 31.743 52 9 31 9 158 18.4 10.3 6 5 5 7 8 5 8 10 10953641.88 55443836.31 59152970.75 103031091.6 6 8 8 9 cell differentiation;metabolic process cytoplasm;membrane;ribosome RNA binding;structural molecule activity Pf00366 27207 ENSMUSG00000003429.11 Rps11 7 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High Q9Z2E9 Seipin OS=Mus musculus OX=10090 GN=Bscl2 PE=1 SV=2 0 44.662 31 8 31 1 383 43.1 6.14 3 5 6 8 5 5 12 9 295217.5625 885770.875 1671484.375 1 1 1 Met-loss [N-Term]; Acetyl [N-Term] cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process endoplasmic reticulum;membrane Pf06775 14705 ENSMUSG00000071657.12 Bscl2 19 0 High Q9D6M3 Mitochondrial glutamate carrier 1 OS=Mus musculus OX=10090 GN=Slc25a22 PE=1 SV=1 0 92.896 55 14 31 14 323 34.6 9.09 2 2 2 13 2 3 2 24 4006379.961 5545087.438 9001679.484 201857909.8 8 4 5 14 transport membrane;mitochondrion transporter activity Pf00153 68267 ENSMUSG00000019082.18 Slc25a22 7 Organic anion transporters 0 High Q9CRB9 MICOS complex subunit Mic19 OS=Mus musculus OX=10090 GN=Chchd3 PE=1 SV=1 0 60.614 59 14 31 14 227 26.3 8.37 6 2 3 13 8 2 3 18 36491362.57 12171462.59 24388026.5 186078828.5 12 5 8 12 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;membrane;mitochondrion;nucleus protein binding;structural molecule activity "Pf05300, Pf06747" 66075 ENSMUSG00000053768.13 Chchd3 6 0 High Q9QYC7 Vitamin K-dependent gamma-carboxylase OS=Mus musculus OX=10090 GN=Ggcx PE=1 SV=1 0 67.411 22 17 31 17 757 87.1 8.02 17 31 676663.875 345270327 1 15 metabolic process endoplasmic reticulum;membrane catalytic activity Pf05090 56316 ENSMUSG00000053460.8; ENSMUSG00000103019.2 Ggcx 6; CHR_MG184_PATCH Gamma-carboxylation of protein precursors Ubiquinone and other terpenoid-quinone biosynthesis 0 High P03977 Ig kappa chain V-III region 50S10.1 OS=Mus musculus OX=10090 PE=1 SV=1 0 39.232 68 4 30 1 111 12 5.06 4 2 1 2 12 10 3 5 101282883.5 165777044.3 133991003.8 77049023.75 4 4 3 3 Pf07686 3 High P27659 60S ribosomal protein L3 OS=Mus musculus OX=10090 GN=Rpl3 PE=1 SV=3 0 26.33 28 11 30 11 403 46.1 10.21 3 7 8 8 3 7 10 10 5305793.688 40603327 31626953.75 43303850.5 3 7 7 6 cell organization and biogenesis;metabolic process;response to stimulus cytoplasm;cytosol;nucleus;ribosome RNA binding;structural molecule activity Pf00297 27367 ENSMUSG00000060036.13 Rpl3 15 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q8BFU2 Histone H2A type 3 OS=Mus musculus OX=10090 GN=H2aw PE=1 SV=3 0 19.426 46 6 30 2 130 14.1 11.05 5 3 3 4 12 6 6 6 1949785.875 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus chromosome;nucleus DNA binding;protein binding "Pf00125, Pf00808" 319162 ENSMUSG00000078851.4 Hist3h2a 11 RMTs methylate histone arginines; Meiotic Recombination; Mus musculus biological processes; Ub-specific processing proteases; NoRC negatively regulates rRNA expression; UCH proteinases; Metalloprotease DUBs; Meiotic Synapsis Alcoholism; Systemic lupus erythematosus 0 High A0A075B5L0 Immunoglobulin kappa variable 10-95 OS=Mus musculus OX=10090 GN=Igkv10-95 PE=4 SV=7 0 33.242 36 2 30 1 95 10.4 4.94 2 1 1 1 23 2 3 2 1526878.25 1 Acetyl [N-Term] "Pf00047, Pf07679, Pf07686" ENSMUSG00000094902.2 6 0 High P01655 Ig kappa chain V-III region PC 7132 OS=Mus musculus OX=10090 PE=1 SV=1 0 46.597 80 4 30 1 112 12 5.34 3 3 1 2 10 12 3 5 9932580 3202440.25 4575413 1 1 1 response to stimulus Pf07686 626583 Igkv3-2 6 0 High G3UYD5 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase OS=Mus musculus OX=10090 GN=Gne PE=1 SV=1 0 42.259 31 12 30 12 479 53.4 7.37 5 9 9 7 10 13 808643.5 29875052.63 33454524.88 60935168.63 1 7 6 8 metabolic process catalytic activity "Pf02350, Pf07085" ENSMUSG00000028479.18 4 0 High Q6ZWN5 40S ribosomal protein S9 OS=Mus musculus OX=10090 GN=Rps9 PE=1 SV=3 0 18.07 45 11 29 11 194 22.6 10.65 3 6 7 5 4 9 10 6 14044499.69 59835299 66921894 87375363 8 9 9 11 metabolic process;regulation of biological process cytoplasm;membrane;nucleus;ribosome RNA binding;structural molecule activity;translation regulator activity "Pf00163, Pf01479" 76846 ENSMUSG00000006333.14 Rps9 7 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High Q61425 "Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Hadh PE=1 SV=2" 0 46.593 41 7 29 7 314 34.4 8.65 5 4 4 6 5 10 6 8 11932383.63 28751505.47 16962990.94 44844995.38 7 7 6 7 metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf00070, Pf00725, Pf01266, Pf02737, Pf13450" 15107 ENSMUSG00000027984.8 Hadh 3 Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA "Fatty acid metabolism; Tryptophan metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Lysine degradation; Fatty acid degradation; Butanoate metabolism; Fatty acid elongation" 0 High P06328 Ig heavy chain V region 1-72 OS=Mus musculus OX=10090 GN=Ighv1-72 PE=1 SV=2 0 23.329 56 5 29 3 117 12.9 9.29 5 3 4 2 14 5 6 4 85117783.59 42306311 93798875 38058315.75 4 3 4 3 2 High Q8R081 Heterogeneous nuclear ribonucleoprotein L OS=Mus musculus OX=10090 GN=Hnrnpl PE=1 SV=2 0 61.81 36 13 29 13 586 63.9 8.1 12 3 5 2 19 3 5 2 31895650.03 16033753.38 36008462.38 14169643.5 11 4 9 4 cell communication;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;nucleus DNA binding;protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 15388 ENSMUSG00000015165.16 Hnrnpl 7 mRNA Splicing - Major Pathway 0 High A0A0A0MQA5 Tubulin alpha chain (Fragment) OS=Mus musculus OX=10090 GN=Tuba4a PE=1 SV=1 0 59.964 26 13 28 1 477 52.9 5.19 5 1 12 5 2 21 cell organization and biogenesis catalytic activity;nucleotide binding;protein binding;structural molecule activity "Pf00091, Pf03953" ENSMUSG00000026202.13 1 0 High O70503 Very-long-chain 3-oxoacyl-CoA reductase OS=Mus musculus OX=10090 GN=Hsd17b12 PE=1 SV=1 0 46.261 41 10 28 10 312 34.7 9.52 6 2 4 8 7 3 4 14 26493359.06 15316683 29680003.25 227137916.3 9 5 6 11 cell organization and biogenesis;metabolic process;regulation of biological process endoplasmic reticulum;membrane catalytic activity;protein binding "Pf00106, Pf02719, Pf08659, Pf13460" 56348 ENSMUSG00000027195.10 Hsd17b12 2 Synthesis of very long-chain fatty acyl-CoAs Fatty acid metabolism; Steroid hormone biosynthesis; Metabolic pathways; Fatty acid elongation; Biosynthesis of unsaturated fatty acids 0 High Q921R2 40S ribosomal protein S13 OS=Mus musculus OX=10090 GN=Rps13 PE=1 SV=1 0 24.935 48 7 28 7 140 16.1 10.71 3 6 5 4 5 10 6 7 11220579.5 41188505.25 40114156.25 44976177.5 4 6 5 5 metabolic process;regulation of biological process membrane;nucleus;ribosome RNA binding;structural molecule activity "Pf00312, Pf08069" 68052 ENSMUSG00000090862.3 Rps13 7 0 High P70302 Stromal interaction molecule 1 OS=Mus musculus OX=10090 GN=Stim1 PE=1 SV=2 0 83.563 31 18 28 15 685 77.5 6.54 18 28 911142.6719 7471140.375 150489516 2 3 13 cell differentiation;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;endoplasmic reticulum;membrane metal ion binding;protein binding;transporter activity "Pf00430, Pf04111, Pf07647" 20866 ENSMUSG00000030987.5 Stim1 7 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Ion homeostasis Platelet activation; Calcium signaling pathway 1 High Q9CR68 "Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Mus musculus OX=10090 GN=Uqcrfs1 PE=1 SV=1" 0 43.891 25 7 28 7 274 29.3 8.7 6 4 3 4 14 6 4 4 32457955.17 20343131.13 17618526.88 47267259.38 7 6 4 5 metabolic process;response to stimulus;transport membrane;mitochondrion catalytic activity;metal ion binding;protein binding;transporter activity "Pf00355, Pf02921, Pf09165" 66694 ENSMUSG00000038462.3 Uqcrfs1 13 Respiratory electron transport Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 High P61358 60S ribosomal protein L27 OS=Mus musculus OX=10090 GN=Rpl27 PE=1 SV=2 0 26.523 43 6 28 6 136 15.8 10.56 4 4 5 5 6 5 10 7 12561066.44 26712826.63 45135445.25 40977127 7 6 7 6 metabolic process membrane;nucleus;ribosome RNA binding;structural molecule activity "Pf00467, Pf01777" 19942; 108167922 ENSMUSG00000063316.13; ENSMUSG00000073640.2 Rpl27; LOC108167922 11; 18 Ribosome 0 High P56501 Mitochondrial uncoupling protein 3 OS=Mus musculus OX=10090 GN=Ucp3 PE=1 SV=1 0 66.601 54 15 28 15 308 33.9 9.55 2 15 2 26 5428353.574 3977393.828 9809582.375 200229233.5 6 2 6 15 Met-loss [N-Term] metabolic process;response to stimulus;transport membrane;mitochondrion transporter activity Pf00153 22229 ENSMUSG00000032942.14 Ucp3 7 The proton buffering model; The fatty acid cycling model 0 High Q8BX70 Vacuolar protein sorting-associated protein 13C OS=Mus musculus OX=10090 GN=Vps13c PE=1 SV=2 0 64.807 7 19 27 19 3748 419.8 6.81 3 12 10 3 12 12 5419869.109 13400107.44 37842813.88 59708896.5 6 7 11 13 cell organization and biogenesis cytosol;membrane;mitochondrion "Pf06650, Pf12624" 320528 ENSMUSG00000035284.10 Vps13c 9 0 High Q8BKI2 Trinucleotide repeat-containing gene 6B protein OS=Mus musculus OX=10090 GN=Tnrc6b PE=1 SV=2 0 62.867 17 18 27 18 1810 191.8 6.3 18 1 1 25 1 1 28082115.38 9029981 2358477.25 1518711.375 16 5 2 1 regulation of biological process cytoplasm RNA binding "Pf10427, Pf13893" 213988 ENSMUSG00000047888.9 Tnrc6b 15 Post-transcriptional silencing by small RNAs 0 High A0A0R4J225 Seipin OS=Mus musculus OX=10090 GN=Bscl2 PE=1 SV=1 0 31.922 23 8 27 1 443 49.6 6.64 3 4 6 7 5 4 10 8 18902620.75 92706456.5 122772339 151910433.4 4 6 6 7 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process endoplasmic reticulum;membrane Pf06775 14705 ENSMUSG00000071657.12 Bscl2 19 7 High Q8C2Q8 ATP synthase subunit gamma OS=Mus musculus OX=10090 GN=Atp5c1 PE=1 SV=1 0 53.823 53 13 27 13 274 30.2 8.84 1 1 4 13 2 1 4 20 6159040.656 11006450.63 22965970 155587228 5 5 7 10 metabolic process;transport membrane;mitochondrion catalytic activity;RNA binding;transporter activity Pf00231 11949 ENSMUSG00000025781.14 Atp5c1 2 0 High Q9DB15 "39S ribosomal protein L12, mitochondrial OS=Mus musculus OX=10090 GN=Mrpl12 PE=1 SV=2" 0 38.741 56 9 27 9 201 21.7 9.29 1 3 4 9 1 3 6 17 3317855.75 24510548.75 36293515.75 245709405.4 3 6 6 7 cell organization and biogenesis;metabolic process;regulation of biological process mitochondrion;ribosome structural molecule activity Pf00542 56282 ENSMUSG00000039640.7 Mrpl12 11 Mitochondrial translation termination; Mitochondrial translation elongation Ribosome 0 High P01635 Ig kappa chain V-V region K2 (Fragment) OS=Mus musculus OX=10090 PE=1 SV=1 0 21.931 41 4 27 2 115 12.6 8.31 3 4 3 4 12 6 4 5 144380228.5 65423683.5 71331269.5 55711138 3 3 3 3 "Pf00047, Pf07679, Pf07686, Pf13927" 619960 ENSMUSG00000095007.1 Igkv12-41 6 1 High A0A0A6YYE7 Immunoglobulin kappa variable 4-57 (Fragment) OS=Mus musculus OX=10090 GN=Igkv4-57 PE=4 SV=2 0 24.918 39 3 27 1 117 12.7 8.91 3 2 3 3 10 4 8 5 44778272.5 36619136.63 68373386.5 35591242.5 2 2 2 2 response to stimulus "Pf00047, Pf07686" 235952 ENSMUSG00000076556.3 Igkv4-57 6 1 High Q01853 Transitional endoplasmic reticulum ATPase OS=Mus musculus OX=10090 GN=Vcp PE=1 SV=4 0 44.104 16 10 27 10 806 89.3 5.26 7 5 7 3 8 7 9 3 30644860.16 31306070.75 56833483.88 33349120.75 10 9 10 9 Met-loss+Acetyl [N-Term] cell communication;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;endoplasmic reticulum;membrane;nucleus;proteasome catalytic activity;enzyme regulator activity;nucleotide binding;protein binding;RNA binding "Pf00004, Pf00910, Pf01057, Pf01078, Pf02359, Pf02933, Pf05496, Pf05673, Pf06068, Pf07724, Pf07726, Pf07728, Pf09336, Pf13191, Pf13207, Pf13401" 269523 ENSMUSG00000028452.7 Vcp 4 N-glycan trimming in the ER and Calnexin/Calreticulin cycle; Protein methylation; Translesion Synthesis by POLH; HSF1 activation; Ovarian tumor domain proteases; Hedgehog ligand biogenesis; ABC-family proteins mediated transport; Neutrophil degranulation Legionellosis; Protein processing in endoplasmic reticulum 0 High A0A075B5R5 Immunoglobulin heavy variable 4-1 (Fragment) OS=Mus musculus OX=10090 GN=Ighv4-1 PE=1 SV=7 0 18.794 49 6 27 5 116 12.9 8.9 6 4 4 4 11 5 6 5 54563222.38 36213533 57865266.5 35337019 6 4 5 4 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000076655.2 LOC668418 12 1 High Q9DBB9 Carboxypeptidase N subunit 2 OS=Mus musculus OX=10090 GN=Cpn2 PE=1 SV=2 0 71.506 33 14 27 14 547 60.4 5.88 14 27 763460.4063 122516105.8 2 9 extracellular protein binding "Pf12799, Pf13306, Pf13855" 71756 ENSMUSG00000023176.8 Cpn2 16 Regulation of Complement cascade 0 High O70423 Membrane primary amine oxidase OS=Mus musculus OX=10090 GN=Aoc3 PE=1 SV=3 0 76.01 24 12 27 12 765 84.5 6.42 12 27 5176210.297 3855675.75 3777170.625 225349720.5 5 1 2 11 cellular component movement;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;endoplasmic reticulum;endosome;Golgi;membrane catalytic activity;metal ion binding;protein binding "Pf01179, Pf02727, Pf02728" 11754 ENSMUSG00000019326.14 Aoc3 11 Phase I - Functionalization of compounds "Metabolic pathways; Glycine, serine and threonine metabolism; beta-Alanine metabolism; Phenylalanine metabolism; Tyrosine metabolism" 0 High Q9CQ62 "2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial OS=Mus musculus OX=10090 GN=Decr1 PE=1 SV=1" 0 41.743 34 9 27 9 335 36.2 8.95 6 2 2 8 9 4 3 11 23092274.25 34023073.5 21620764.38 78685980 6 6 4 7 cell organization and biogenesis;metabolic process cytosol;mitochondrion;nucleus catalytic activity;nucleotide binding "Pf00106, Pf08659, Pf13561" 67460 ENSMUSG00000028223.8 Decr1 4 mitochondrial fatty acid beta-oxidation of unsaturated fatty acids 0 High E9Q7B0 Procollagen-proline 4-dioxygenase OS=Mus musculus OX=10090 GN=P4ha1 PE=1 SV=1 0 74.472 41 16 26 2 454 51.7 6.71 16 26 16317351 1 cell organization and biogenesis;metabolic process endoplasmic reticulum;membrane;mitochondrion catalytic activity;metal ion binding;protein binding "Pf03171, Pf08336, Pf13640" 18451 ENSMUSG00000019916.14 P4ha1 10 0 High E9QN70 Laminin subunit beta-1 OS=Mus musculus OX=10090 GN=Lamb1 PE=1 SV=1 0 61.127 12 17 26 17 1834 202.3 5.01 17 1 25 1 23382245.61 1633224.922 2643772.625 13480831.5 17 2 2 7 cell differentiation;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport extracellular;nucleus catalytic activity;motor activity;protein binding;structural molecule activity "Pf00038, Pf00053, Pf00055, Pf01442, Pf01576, Pf05557, Pf05698, Pf06008, Pf07111, Pf08317, Pf08647, Pf09731, Pf13476, Pf13868, Pf15346" 16777 ENSMUSG00000002900.16 Lamb1 12 Focal adhesion; Toxoplasmosis; Small cell lung cancer; Pathways in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway; Amoebiasis 0 High P01633 Ig kappa chain V19-17 OS=Mus musculus OX=10090 GN=Igk-V19-17 PE=1 SV=1 0 13.536 31 4 26 1 149 16.4 6.92 4 4 4 3 8 5 8 5 14523719 11718530 18828746 9343644 1 1 1 1 response to stimulus membrane Pf07686 667865 Igkv6-17 6 1 High O54991 Contactin-associated protein 1 OS=Mus musculus OX=10090 GN=Cntnap1 PE=1 SV=2 0 59.411 14 17 26 17 1385 156.2 7.06 17 26 668044.25 157897452.5 2 15 cell organization and biogenesis membrane protein binding "Pf00054, Pf00147, Pf00754, Pf02210" 53321 ENSMUSG00000017167.6 Cntnap1 11 Cell adhesion molecules (CAMs) 0 High P01631 Ig kappa chain V-II region 26-10 OS=Mus musculus OX=10090 PE=1 SV=1 0 20.244 39 4 26 1 113 12.3 8.88 3 2 3 2 7 6 9 4 6404819.5 5278884.5 4702217.5 1 1 1 metal ion binding Pf07686 16098 Igkv1-117 6 0 High P47911 60S ribosomal protein L6 OS=Mus musculus OX=10090 GN=Rpl6 PE=1 SV=3 0 25.395 33 9 26 9 296 33.5 10.7 2 9 6 7 3 9 6 8 12319622.38 51092703.25 49042126.75 60050347.25 7 7 7 7 cell organization and biogenesis;metabolic process cytoplasm;membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity "Pf01159, Pf03868" 19988 ENSMUSG00000029614.13 Rpl6 5 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q80X68 Citrate synthase OS=Mus musculus OX=10090 GN=Csl PE=1 SV=1 0 17.406 13 6 26 1 466 52.3 8.79 4 5 2 5 6 10 3 7 2377746.75 5949282.5 2623664.75 8978827 1 1 1 1 metabolic process mitochondrion catalytic activity Pf00285 71832 ENSMUSG00000046934.5 Csl 10 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Biosynthesis of amino acids; 2-Oxocarboxylic acid metabolism; Carbon metabolism; Glyoxylate and dicarboxylate metabolism 0 High P27773 Protein disulfide-isomerase A3 OS=Mus musculus OX=10090 GN=Pdia3 PE=1 SV=2 0 76.765 47 18 26 18 505 56.6 6.21 18 26 610773.6875 938832.9375 147426089.5 1 1 14 cell communication;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;endoplasmic reticulum;extracellular;membrane;mitochondrion;nucleus;organelle lumen catalytic activity;protein binding;RNA binding "Pf00085, Pf13098, Pf13848, Pf13899, Pf13905" 14827 ENSMUSG00000027248.13 Pdia3 2 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Calnexin/calreticulin cycle; ER-Phagosome pathway" Antigen processing and presentation; Protein processing in endoplasmic reticulum 0 High P67778 Prohibitin OS=Mus musculus OX=10090 GN=Phb PE=1 SV=1 0 88.573 64 13 26 13 272 29.8 5.76 13 26 1214947.75 1517829.875 385845793 3 1 11 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;endosome;membrane;mitochondrion;nucleus DNA binding;protein binding Pf01145 18673 ENSMUSG00000038845.11 Phb 11 RAF activation; Interleukin-20 family signaling; Processing of SMDT1 0 High G3UYC6 Synaptotagmin-like protein 4 (Fragment) OS=Mus musculus OX=10090 GN=Sytl4 PE=1 SV=8 0.006 2.111 5 1 26 1 185 21.6 9.07 1 1 1 1 6 8 6 6 496108449.6 770161795 655037268.6 667512208 1 1 1 1 regulation of biological process;transport protein binding Pf02318 ENSMUSG00000031255.14 X 0 High H7BX95 Serine/arginine-rich splicing factor 1 OS=Mus musculus OX=10090 GN=Srsf1 PE=1 SV=1 0 27.951 36 8 26 8 253 28.3 10.08 2 4 5 6 2 5 11 8 6961361.25 58373322 110823423 63361748.75 4 6 7 6 metabolic process nucleus protein binding;RNA binding "Pf00076, Pf13893, Pf14259" ENSMUSG00000018379.17; ENSMUSG00000098301.6 11; CHR_MG3829_PATCH 0 High P56480 "ATP synthase subunit beta, mitochondrial OS=Mus musculus OX=10090 GN=Atp5f1b PE=1 SV=2" 0 93.624 50 18 26 18 529 56.3 5.34 18 26 3482277.469 4364402 3974274.25 149561502.2 7 2 2 14 cell differentiation;cellular homeostasis;metabolic process;regulation of biological process;transport cell surface;membrane;mitochondrion;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding;receptor activity;transporter activity "Pf00006, Pf00306, Pf02874" 11947 ENSMUSG00000025393.12 Atp5b 10 Cristae formation; Formation of ATP by chemiosmotic coupling Metabolic pathways; Huntington's disease; Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High A0A0A0MQ73 [Histone H3]-lysine(4) N-trimethyltransferase OS=Mus musculus OX=10090 GN=Kmt2d PE=1 SV=1 0 51.419 5 21 26 21 5588 599.9 5.78 21 26 28183980.16 3418100.25 19 2 cell growth;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus nucleus catalytic activity;DNA binding;metal ion binding;protein binding "Pf00505, Pf00628, Pf00856, Pf05964, Pf05965, Pf13639, Pf13771, Pf13832, Pf15446" 381022 ENSMUSG00000048154.16 Kmt2d; Mll2 15 Lysine degradation 0 High F8WJ41 40S ribosomal protein S15a (Fragment) OS=Mus musculus OX=10090 GN=Rps15a PE=1 SV=1 0 16.603 53 7 26 7 108 12.3 10.15 2 4 6 7 2 4 8 12 6081883.813 27913891.38 46001598.75 87730416 5 6 7 7 metabolic process mitochondrion;ribosome structural molecule activity Pf00410 ENSMUSG00000008683.16 7 0 High Q60668 Heterogeneous nuclear ribonucleoprotein D0 OS=Mus musculus OX=10090 GN=Hnrnpd PE=1 SV=2 0 31.043 30 9 26 8 355 38.3 7.81 9 3 3 3 15 3 4 4 73943919.63 46809378.63 50188899.25 48865610.25 8 7 7 7 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;nucleus DNA binding;protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 11991 ENSMUSG00000000568.15 Hnrnpd 5 mRNA Splicing - Major Pathway; AUF1 (hnRNP D0) binds and destabilizes mRNA 1 High P61982 14-3-3 protein gamma OS=Mus musculus OX=10090 GN=Ywhag PE=1 SV=2 0 31.092 49 11 25 8 247 28.3 4.89 3 4 4 9 4 5 5 11 16812464.77 53381168.99 47800387.5 93087593.5 8 10 8 9 metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;membrane catalytic activity;protein binding;RNA binding Pf00244 22628 ENSMUSG00000051391.9 Ywhag 5 Translocation of GLUT4 to the plasma membrane; Anchoring of the basal body to the plasma membrane; Activation of BAD and translocation to mitochondria ; AURKA Activation by TPX2; RHO GTPases activate PKNs; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex Epstein-Barr virus infection; Hippo signaling pathway; Oocyte meiosis; Cell cycle; PI3K-Akt signaling pathway; Viral carcinogenesis 3 High P15864 Histone H1.2 OS=Mus musculus OX=10090 GN=H1-2 PE=1 SV=2 0 36.062 41 11 25 3 212 21.3 11 8 5 6 4 10 5 6 4 35554111.19 45622825.13 42840826 70613921 8 6 7 7 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process chromosome;nucleus DNA binding;protein binding;RNA binding Pf00538 50708 ENSMUSG00000036181.2 Hist1h1c 13 7 High Q924L1 LETM1 domain-containing protein 1 OS=Mus musculus OX=10090 GN=Letmd1 PE=1 SV=1 0 35.061 27 8 25 8 360 41.7 10.54 3 1 5 8 6 2 7 10 18033432.63 20382527.63 47151959.38 93470265.5 7 5 7 7 cellular homeostasis membrane;mitochondrion Pf07766 68614 ENSMUSG00000037353.8 Letmd1 15 0 High A0A0G2JH12 Hyccin OS=Mus musculus OX=10090 GN=Fam126a PE=1 SV=1 0 50.429 37 8 25 2 338 37.2 8.51 5 7 5 5 11 9 18692823 25744096 30066409 2 2 2 Pf09790 ENSMUSG00000028995.14 5 0 High Q8JZU2 "Tricarboxylate transport protein, mitochondrial OS=Mus musculus OX=10090 GN=Slc25a1 PE=1 SV=1" 0 59.22 61 15 25 15 311 33.9 9.89 2 15 2 23 3592490.125 8243269.063 35318069 529881051 3 5 8 14 transport membrane;mitochondrion;nucleus transporter activity Pf00153 13358 ENSMUSG00000003528.14 Slc25a1 16 Gluconeogenesis; Fatty acyl-CoA biosynthesis 0 High Q3UV17 "Keratin, type II cytoskeletal 2 oral OS=Mus musculus OX=10090 GN=Krt76 PE=1 SV=1" 0 13.716 6 6 25 1 594 62.8 8.43 6 4 3 3 11 6 4 4 73109824 54235028 66022744 352908192 1 1 1 1 nucleus catalytic activity;motor activity;protein binding;structural molecule activity "Pf00038, Pf01576, Pf10473" 77055 ENSMUSG00000075402.1 Krt76 15 Formation of the cornified envelope 0 High P14131 40S ribosomal protein S16 OS=Mus musculus OX=10090 GN=Rps16 PE=1 SV=4 0 17.682 48 8 25 8 146 16.4 10.21 4 4 5 5 7 6 6 6 5703072.344 28507309.75 30558785.25 49229658 6 7 7 7 Met-loss [N-Term] metabolic process membrane;ribosome RNA binding;structural molecule activity Pf00380 100039355; 20055 ENSMUSG00000037563.15 Rps16-ps2; Rps16 5; 7 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High A0A140T8P7 Immunoglobulin kappa variable 8-21 (Fragment) OS=Mus musculus OX=10090 GN=Igkv8-21 PE=1 SV=2 0 12.808 33 4 25 1 120 13.1 8.28 4 4 4 2 8 6 6 5 8845202 6696675.5 7154646.5 2899774.25 1 1 1 1 Pf07686 620400 ENSMUSG00000076586.2 Igkv8-21 6 0 High A0A075B5N3 Immunoglobulin kappa variable 8-28 OS=Mus musculus OX=10090 GN=Igkv8-28 PE=1 SV=7 0 26.413 60 5 25 3 101 10.9 5.94 5 3 5 2 9 3 11 2 48942522.44 27752194 127905897 15873801.25 4 4 4 2 "Pf07679, Pf07686" ENSMUSG00000094356.2 6 1 High A0A3B2WDD2 Ribosomal protein OS=Mus musculus OX=10090 GN=Rpl10a PE=1 SV=1 0 29.514 37 7 25 7 190 21.6 9.98 4 4 5 7 7 5 5 8 9541728.375 36899668 32958010.25 47799947.5 5 5 6 6 0 High Q61136 Serine/threonine-protein kinase PRP4 homolog OS=Mus musculus OX=10090 GN=Prpf4b PE=1 SV=3 0 50.709 14 13 25 13 1007 116.9 10.23 7 10 7 8 10 7 245800.3438 30757332.06 59077653.94 27322087.88 1 11 12 8 Met-loss+Acetyl [N-Term] metabolic process chromosome;nucleus;spliceosomal complex catalytic activity;nucleotide binding;RNA binding "Pf00069, Pf07714" 19134 ENSMUSG00000021413.8 Prpf4b 13 0 High Q60932 Voltage-dependent anion-selective channel protein 1 OS=Mus musculus OX=10090 GN=Vdac1 PE=1 SV=3 0 29.403 33 8 24 8 296 32.3 8.43 8 3 3 6 11 3 3 7 21320620.25 19851332.25 17486914.5 55874695 7 6 5 7 cell communication;cell death;cell differentiation;defense response;regulation of biological process;response to stimulus;transport membrane;mitochondrion;nucleus nucleotide binding;protein binding;transporter activity Pf01459 22333 ENSMUSG00000020402.11 Vdac1 11 Pink/Parkin Mediated Mitophagy NOD-like receptor signaling pathway; HTLV-I infection; Huntington's disease; Parkinson's disease; cGMP-PKG signaling pathway; Calcium signaling pathway; Influenza A 0 High P06330 Ig heavy chain V region AC38 205.12 OS=Mus musculus OX=10090 PE=1 SV=1 0 24.988 65 5 24 3 118 12.9 7.11 2 4 3 3 5 8 8 3 171826515.5 156769184 126011136.5 80310296 2 1 2 1 "Pf00047, Pf07686" 380820 IghmAC38.205.12 12 0 High A0A075B5N7 Immunoglobulin kappa variable 6-13 OS=Mus musculus OX=10090 GN=Igkv6-13 PE=1 SV=7 0 17.499 58 5 24 3 95 10.4 6.51 5 5 3 3 9 5 6 4 145952926.6 87974573.5 154855689.5 100500788.5 6 5 5 5 "Pf00047, Pf07679, Pf07686" ENSMUSG00000076594.2 6 2 High A0A2R8VHP3 Predicted pseudogene 5478 OS=Mus musculus OX=10090 GN=Gm5478 PE=1 SV=1 0 15.166 9 6 24 2 535 57.9 6.2 4 2 2 5 9 4 3 8 25636437 12149755.25 21056517 70203167 2 2 2 2 0 High P62242 40S ribosomal protein S8 OS=Mus musculus OX=10090 GN=Rps8 PE=1 SV=2 0 28.238 51 9 24 9 208 24.2 10.32 1 4 6 7 1 4 9 10 7849898.125 38496511.13 39964913 69255899 3 5 5 6 metabolic process cytoplasm;cytosol;endoplasmic reticulum;membrane;nucleus;ribosome RNA binding;structural molecule activity Pf01201 20116; 100040298 ENSMUSG00000047675.15 Rps8; Gm15501 4; 7 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High P43274 Histone H1.4 OS=Mus musculus OX=10090 GN=H1-4 PE=1 SV=2 0 29.575 33 8 24 2 219 22 11.11 6 5 5 5 7 5 6 6 8113297.5 7022703.5 12402836.5 14456984.5 2 2 2 2 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process chromosome;nucleus DNA binding;metal ion binding;nucleotide binding;protein binding;RNA binding Pf00538 50709 ENSMUSG00000051627.2 Hist1h1e 13 0 High Q9QYB2 Dachshund homolog 1 OS=Mus musculus OX=10090 GN=Dach1 PE=1 SV=1 0 31.096 13 10 24 10 751 77.9 8.53 8 8 4 9 10 5 518584.5938 53209009 51260786.5 52863363 1 8 7 7 cell organization and biogenesis;cell proliferation;development;metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus DNA binding;protein binding Pf02437 13134 ENSMUSG00000055639.16 Dach1 14 0 High P50446 "Keratin, type II cytoskeletal 6A OS=Mus musculus OX=10090 GN=Krt6a PE=1 SV=3" 0 30.148 15 10 24 1 553 59.3 7.94 6 6 2 4 9 9 2 4 736966.125 3177817.25 1549251.25 2345129.5 1 1 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus catalytic activity;motor activity;structural molecule activity "Pf00038, Pf01576, Pf04111, Pf05957, Pf12128, Pf13166" 16687 ENSMUSG00000058354.6 Krt6a 15 Formation of the cornified envelope 0 High A0A0R4J038 Bradykinin OS=Mus musculus OX=10090 GN=Kng1 PE=1 SV=1 0 46.482 26 12 24 12 661 73.1 6.6 6 9 6 7 9 8 879055.4219 20254391.75 52124041.5 32845308 3 6 7 6 cellular homeostasis;coagulation;defense response;regulation of biological process;response to stimulus extracellular enzyme regulator activity;protein binding Pf00031 16644 ENSMUSG00000022875.17 Kng1 16 Complement and coagulation cascades 0 High P01746 Ig heavy chain V region 93G7 OS=Mus musculus OX=10090 PE=2 SV=1 0 11.524 17 2 24 1 140 15.5 8.4 2 2 2 2 6 5 8 5 103357144 97156472 112890416 65746400 1 1 1 1 Pf07686 238440 LOC238440 12 0 High A0A140T8M4 Immunoglobulin kappa variable 8-19 OS=Mus musculus OX=10090 GN=Igkv8-19 PE=1 SV=2 0 17.209 60 5 24 2 101 11.1 5.25 5 4 4 2 8 5 6 5 8109805.5 6414515.25 2654346.5 3 2 1 "Pf07679, Pf07686, Pf13927" ENSMUSG00000096594.2 6 0 High Q8BUE4 Ferroptosis suppressor protein 1 OS=Mus musculus OX=10090 GN=Aifm2 PE=1 SV=1 0 47.672 39 13 23 13 373 40.6 8.98 2 1 1 13 4 1 1 17 60322588.53 59630681.75 54391345.63 160577146.5 6 3 5 9 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;cytosol;membrane;mitochondrion catalytic activity;DNA binding;nucleotide binding "Pf00070, Pf07992" 71361 ENSMUSG00000020085.15 Aifm2 10 0 High Q04857 Collagen alpha-1(VI) chain OS=Mus musculus OX=10090 GN=Col6a1 PE=1 SV=1 0 40.185 14 11 23 11 1025 108.4 5.36 11 3 3 17 3 3 41559197.38 21955648.5 31602062.63 11 8 9 cell differentiation;cell organization and biogenesis;response to stimulus extracellular;membrane protein binding "Pf00092, Pf01391, Pf13519, Pf13768" 12833 ENSMUSG00000001119.7 Col6a1 10 ECM proteoglycans; Collagen chain trimerization; Integrin cell surface interactions; NCAM1 interactions; Collagen degradation; Signaling by PDGF; Assembly of collagen fibrils and other multimeric structures Focal adhesion; Protein digestion and absorption; ECM-receptor interaction; PI3K-Akt signaling pathway 0 High P04940 Ig kappa chain V-VI region NQ2-17.4.1 OS=Mus musculus OX=10090 PE=2 SV=1 0 23.25 34 4 23 2 107 11.6 9.36 4 4 3 3 7 7 4 5 46226852.5 66106772 139155367 28426310 4 4 4 4 "Pf00047, Pf07679, Pf07686" 2 High P14873 Microtubule-associated protein 1B OS=Mus musculus OX=10090 GN=Map1b PE=1 SV=2 0 57.655 12 18 23 18 2464 270.1 4.83 18 23 27464018.59 17 Met-loss+Acetyl [N-Term] cell growth;cell organization and biogenesis;cellular component movement;regulation of biological process;transport cytoplasm;cytoskeleton;cytosol;membrane protein binding 17755 ENSMUSG00000052727.5 Map1b; Mtap1b 13 0 High A0A140T8M2 Immunoglobulin kappa variable 12-44 (Fragment) OS=Mus musculus OX=10090 GN=Igkv12-44 PE=4 SV=2 0 15.046 41 4 23 1 115 12.5 7.87 4 4 3 3 7 6 6 4 142869308 73790548.5 107684212.5 59928348 4 4 4 3 "Pf00047, Pf07679, Pf07686" 545851 ENSMUSG00000096422.2 Igkv12-44 6 3 High A0A140T8N9 Immunoglobulin kappa variable 6-32 (Fragment) OS=Mus musculus OX=10090 GN=Igkv6-32 PE=4 SV=2 0 20.099 40 4 23 3 115 12.6 7.85 4 3 4 3 7 4 8 4 24218759 22749081 65093448 26765194.5 3 2 3 3 "Pf00047, Pf07679, Pf07686" 434039 ENSMUSG00000076576.2 Igkv6-32 6 0 High Q9D023 Mitochondrial pyruvate carrier 2 OS=Mus musculus OX=10090 GN=Mpc2 PE=1 SV=1 0 31.195 40 6 23 6 127 14.3 10.61 2 3 6 3 3 17 2993025.219 14368832.38 28153084.13 135612512.5 4 4 5 7 regulation of biological process;transport membrane;mitochondrion;nucleus transporter activity Pf03650 70456 ENSMUSG00000026568.6 Mpc2 1 0 High A6BLY7 "Keratin, type I cytoskeletal 28 OS=Mus musculus OX=10090 GN=Krt28 PE=1 SV=1" 0 6.618 3 2 23 1 462 50.3 5.29 2 2 2 2 6 5 5 7 75298336.25 89259620.88 59415763.5 194968055 3 3 3 3 cytoplasm structural molecule activity Pf00038 70843 ENSMUSG00000055937.1 Krt28 11 Formation of the cornified envelope 0 High A0A075B5R0 Immunoglobulin heavy variable 5-16 OS=Mus musculus OX=10090 GN=Ighv5-16 PE=1 SV=1 0 19.565 33 3 23 3 116 13.2 7.81 3 3 3 3 7 6 6 4 46067453.63 61936818.88 44318106.63 21347957 4 3 3 3 Pf07686 ENSMUSG00000094194.2 12 0 High P97352 Protein S100-A13 OS=Mus musculus OX=10090 GN=S100a13 PE=1 SV=1 0 19.772 42 6 23 6 98 11.2 6.13 4 3 5 1 13 3 6 1 55506700.25 15650463 31031055.5 6139653.75 6 4 5 2 regulation of biological process;transport cytoplasm;cytosol;extracellular;membrane;nucleus metal ion binding;protein binding Pf01023 20196 S100a13 3 0 High A0A140T8P5 Immunoglobulin kappa chain variable 8-24 (Fragment) OS=Mus musculus OX=10090 GN=Igkv8-24 PE=4 SV=2 0 15.706 36 4 23 2 121 13.3 5.94 4 4 4 3 7 6 6 4 14735686 20984122 23745672.25 15439598.25 2 2 2 2 Pf07679 677858 ENSMUSG00000076583.1 Igkv8-24 6 0 High Q8BL97 Serine/arginine-rich splicing factor 7 OS=Mus musculus OX=10090 GN=Srsf7 PE=1 SV=1 0 22.674 25 6 23 6 267 30.8 11.9 3 4 6 5 3 6 9 5 7485510.188 42760537.5 95498265 54949706.25 5 6 5 6 metabolic process;regulation of biological process;transport cytoplasm;nucleus metal ion binding;protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 225027 Srsf7 17 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript Herpes simplex infection; Spliceosome 0 High A0A075B5Y4 Immunoglobulin heavy variable 1-81 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-81 PE=4 SV=1 0 28.62 48 6 23 2 117 13 8.79 6 3 3 2 10 4 6 3 50858419.63 29304942 52430877.13 48053034.75 5 3 4 5 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000094689.1 12 3 High Q9DB20 "ATP synthase subunit O, mitochondrial OS=Mus musculus OX=10090 GN=Atp5po PE=1 SV=1" 0 33.915 47 9 23 9 213 23.3 9.99 2 1 4 7 3 1 5 14 3167420.625 11891007.63 32782994.5 200297906 3 4 6 8 metabolic process;transport membrane;mitochondrion;nucleus catalytic activity;protein binding;transporter activity Pf00213 28080; 102641678 ENSMUSG00000022956.10 Atp5o; LOC100047429; LOC102641678 16; 3 Cristae formation; Formation of ATP by chemiosmotic coupling Metabolic pathways; Huntington's disease; Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High Q62087 Serum paraoxonase/lactonase 3 OS=Mus musculus OX=10090 GN=Pon3 PE=1 SV=2 0 59.882 36 9 23 9 354 39.3 5.74 9 23 597931.0625 165525989.3 1 9 metabolic process;regulation of biological process;response to stimulus extracellular catalytic activity;metal ion binding;protein binding "Pf01731, Pf03088" 269823 ENSMUSG00000029759.9 Pon3 6 Synthesis of 5-eicosatetraenoic acids Metabolic pathways 0 High A0A075B5V7 Immunoglobulin heavy variable V1-43 OS=Mus musculus OX=10090 GN=Ighv1-43 PE=4 SV=1 0 25.052 53 5 23 3 98 10.8 8.98 2 4 3 3 6 7 7 3 15078360 17689769.5 16333469 10306629.5 3 3 2 2 Pf07686 ENSMUSG00000095859.2 12 1 High P50172 Corticosteroid 11-beta-dehydrogenase isozyme 1 OS=Mus musculus OX=10090 GN=Hsd11b1 PE=1 SV=3 0 62.425 69 18 23 18 292 32.3 8.46 18 23 77233.38281 255941864.5 1 16 Met-loss [N-Term] metabolic process;regulation of biological process cytoplasm;endoplasmic reticulum;membrane catalytic activity;nucleotide binding "Pf00106, Pf08643, Pf08659, Pf13460, Pf13561" 15483 ENSMUSG00000016194.14 Hsd11b1 1 Glucocorticoid biosynthesis Steroid hormone biosynthesis; Metabolic pathways; Chemical carcinogenesis; Metabolism of xenobiotics by cytochrome P450 0 High Q62167 ATP-dependent RNA helicase DDX3X OS=Mus musculus OX=10090 GN=Ddx3x PE=1 SV=3 0 33.482 18 10 23 10 662 73.1 7.18 9 3 5 4 9 3 6 5 9644318.656 9186296.375 23517657.56 16559736.63 10 7 9 7 cell death;cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;DNA binding;enzyme regulator activity;nucleotide binding;protein binding;RNA binding "Pf00270, Pf00271, Pf04851" 13205 ENSMUSG00000000787.12 Ddx3x X Neutrophil degranulation RIG-I-like receptor signaling pathway; Hepatitis B; Viral carcinogenesis 0 High A0A075B5U7 Immunoglobulin heavy variable 1-22 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-22 PE=1 SV=1 0 26.908 41 6 23 4 117 13 8.76 6 1 1 1 13 4 5 1 170796335.8 147437348 155506871.8 94124438 6 4 4 4 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000094561.1 LOC673196 12 2 High P99027 60S acidic ribosomal protein P2 OS=Mus musculus OX=10090 GN=Rplp2 PE=1 SV=3 0 61.858 81 7 23 7 115 11.6 4.54 3 5 4 5 3 6 5 9 11211760.94 42881246.5 39494966.88 53754979.75 4 6 6 5 metabolic process membrane;ribosome structural molecule activity Pf00428 67186 ENSMUSG00000025508.13 Rplp2 7 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q8BGZ7 "Keratin, type II cytoskeletal 75 OS=Mus musculus OX=10090 GN=Krt75 PE=1 SV=1" 0 23.899 14 10 23 1 551 59.7 8.31 7 5 2 4 10 7 2 4 1289983.859 48105772.25 4783935.5 2 3 1 cell differentiation;metabolic process;transport catalytic activity;motor activity;protein binding;structural molecule activity;transporter activity "Pf00012, Pf00038, Pf01496, Pf01576, Pf04111, Pf04156, Pf09728, Pf13166" 109052 ENSMUSG00000022986.5 Krt75 15 Formation of the cornified envelope 2 High Q9JK53 Prolargin OS=Mus musculus OX=10090 GN=Prelp PE=1 SV=2 0 38.409 31 11 22 11 378 43.3 9.54 1 7 9 1 9 12 4521484.344 2531702.125 46162350.25 71874604.25 5 2 8 9 cell organization and biogenesis extracellular protein binding;structural molecule activity "Pf01462, Pf12799, Pf13855" 116847 ENSMUSG00000041577.5 Prelp 1 Keratan sulfate degradation; Keratan sulfate biosynthesis 0 High E9Q1Z0 Keratin 90 OS=Mus musculus OX=10090 GN=Krt90 PE=1 SV=1 0 18.358 9 7 22 2 538 58.2 8.25 6 6 3 2 9 7 3 3 98759176 84395641 106547340 343493816 2 2 2 2 cell organization and biogenesis;metabolic process catalytic activity;motor activity;protein binding;structural molecule activity "Pf00038, Pf01576, Pf04111, Pf06810, Pf09728, Pf12128, Pf13166, Pf13514" 239673 ENSMUSG00000048699.4 4732456N10Rik; Krt90 15 0 High P43277 Histone H1.3 OS=Mus musculus OX=10090 GN=H1-3 PE=1 SV=2 0 33.622 37 10 22 1 221 22.1 11.03 6 5 4 5 8 5 4 5 2483340.75 1689263.125 1369434.5 6007075 1 1 1 2 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process chromosome;nucleus DNA binding;protein binding;RNA binding Pf00538 14957 ENSMUSG00000052565.6 Hist1h1d 13 1 High P58252 Elongation factor 2 OS=Mus musculus OX=10090 GN=Eef2 PE=1 SV=2 0 38.269 17 11 22 10 858 95.3 6.83 5 3 1 10 5 3 2 12 6718488.172 5554470.063 7149842.313 39717697.75 7 5 4 8 Met-loss [N-Term] cell differentiation;cell proliferation;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;nucleus;ribosome catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00009, Pf00679, Pf03144, Pf03764, Pf14492" 13629 ENSMUSG00000034994.10 Eef2 10 Peptide chain elongation; Neutrophil degranulation; Protein methylation; Synthesis of diphthamide-EEF2 Oxytocin signaling pathway; AMPK signaling pathway 0 High A0A140T8N5 Immunoglobulin kappa variable 6-23 (Fragment) OS=Mus musculus OX=10090 GN=Igkv6-23 PE=4 SV=2 0 13.501 34 3 22 1 115 12.8 5.73 3 2 2 2 8 3 5 6 13108795.38 2373842.5 6319248.5 5843056.5 1 1 1 1 "Pf00047, Pf07679, Pf07686, Pf13927" 637227 ENSMUSG00000095630.2 Igkv6-23 6 0 High P68254 14-3-3 protein theta OS=Mus musculus OX=10090 GN=Ywhaq PE=1 SV=1 0 25.162 44 7 22 4 245 27.8 4.78 4 4 4 5 5 5 5 7 2131587.648 2623551.344 3061306.688 5567113.125 4 3 3 3 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;Golgi;membrane catalytic activity;DNA binding;protein binding Pf00244 22630; 102634437; 214444 ENSMUSG00000076432.12 Ywhaq; LOC102634437; Gm11226; Ywhaq-ps3; Cdk5rap2 12; 4 Translocation of GLUT4 to the plasma membrane; Activation of BAD and translocation to mitochondria ; RHO GTPases activate PKNs; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex Epstein-Barr virus infection; Hippo signaling pathway; Hepatitis B; Oocyte meiosis; Cell cycle; PI3K-Akt signaling pathway; Viral carcinogenesis 0 High P14148 60S ribosomal protein L7 OS=Mus musculus OX=10090 GN=Rpl7 PE=1 SV=2 0 33.918 33 9 22 9 270 31.4 10.89 1 5 5 7 1 5 7 9 6516004.125 28452255.5 34107634.38 46511945.5 6 6 7 7 Acetyl [N-Term] metabolic process cytoplasm;membrane;nucleus;ribosome DNA binding;protein binding;RNA binding;structural molecule activity "Pf00327, Pf08079" 19989 ENSMUSG00000043716.13 Rpl7 1 Ribosome 0 High P62806 Histone H4 OS=Mus musculus OX=10090 GN=H4c1 PE=1 SV=2 0 22.994 52 6 22 6 103 11.4 11.36 6 2 3 2 12 2 5 3 70527971.78 19395415.23 35408603.93 28871135 6 4 4 4 cell organization and biogenesis;metabolic process;regulation of biological process chromosome;membrane;nucleus DNA binding;protein binding;RNA binding "Pf00125, Pf02969, Pf15630" 320332; 326619; 319160; 319155; 319158; 319161; 69386; 319157; 319159; 326620; 100041230; 319156; 97122; 102641229 ENSMUSG00000096010.2; ENSMUSG00000091405.2; ENSMUSG00000060981.6; ENSMUSG00000069274.3; ENSMUSG00000061482.6; ENSMUSG00000067455.5; ENSMUSG00000064288.4; ENSMUSG00000060678.4; ENSMUSG00000069306.5; ENSMUSG00000069305.3; ENSMUSG00000069266.5; ENSMUSG00000060093.6; ENSMUSG00000060639.5 Hist4h4; Hist1h4a; Hist1h4k; Hist1h4c; Hist1h4i; Hist1h4n; Hist1h4h; Hist1h4f; Hist1h4j; Hist1h4b; Hist1h4m; Hist1h4d; Hist2h4; LOC100862646; LOC102641229 6; 13; 3 Transcriptional regulation by small RNAs; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HATs acetylate histones; Meiotic Recombination; HDMs demethylate histones; Deposition of new CENPA-containing nucleosomes at the centromere; Formation of the beta-catenin:TCF transactivating complex; PRC2 methylates histones and DNA; SUMOylation of chromatin organization proteins; Nonhomologous End-Joining (NHEJ); RMTs methylate histone arginines; NoRC negatively regulates rRNA expression; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Oxidative Stress Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); DNA Damage/Telomere Stress Induced Senescence; SIRT1 negatively regulates rRNA expression; Condensation of Prophase Chromosomes; B-WICH complex positively regulates rRNA expression; RNA Polymerase I Promoter Opening; NoRC negatively regulates rRNA expression; Meiotic Synapsis; G2/M DNA damage checkpoint; PKMTs methylate histone lysines; Mus musculus biological processes; RNA Polymerase I Chain Elongation Alcoholism; Systemic lupus erythematosus; Viral carcinogenesis 0 High Q8K3K7 1-acyl-sn-glycerol-3-phosphate acyltransferase beta OS=Mus musculus OX=10090 GN=Agpat2 PE=1 SV=1 0 55.811 41 10 22 10 278 31 8.88 10 22 565713.6406 1816837.125 209203721 2 1 11 metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;membrane catalytic activity Pf01553 67512 ENSMUSG00000026922.13 Agpat2 2 Neutrophil degranulation; Synthesis of PA Phospholipase D signaling pathway; Fat digestion and absorption; Metabolic pathways; Glycerophospholipid metabolism; Glycerolipid metabolism 0 High Q9CQF3 Cleavage and polyadenylation specificity factor subunit 5 OS=Mus musculus OX=10090 GN=Nudt21 PE=1 SV=1 0 40.686 50 9 22 9 227 26.2 8.82 7 2 4 3 8 2 9 3 26783490.56 19186313.03 87931793.23 106759474.7 9 4 9 6 cell organization and biogenesis;metabolic process nucleus catalytic activity;protein binding;RNA binding Pf13869 68219 ENSMUSG00000031754.10 Nudt21 8 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Processing of Intronless Pre-mRNAs; Cleavage of Growing Transcript in the Termination Region mRNA surveillance pathway 0 High P62918 60S ribosomal protein L8 OS=Mus musculus OX=10090 GN=Rpl8 PE=1 SV=2 0 28.815 40 10 22 10 257 28 11.03 2 8 3 5 2 9 5 6 11555058.19 64074034.75 37999080.75 76683368 6 10 7 8 metabolic process;response to stimulus cytoplasm;membrane;ribosome protein binding;RNA binding;structural molecule activity "Pf00181, Pf03947" 26961 ENSMUSG00000003970.8 Rpl8 15 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q9D7N9 Adipocyte plasma membrane-associated protein OS=Mus musculus OX=10090 GN=Apmap PE=1 SV=1 0 82.385 50 16 22 16 415 46.4 6.32 16 22 191462.9063 52708.23047 3482505 89491784.25 1 1 1 11 metabolic process cell surface;endoplasmic reticulum;membrane catalytic activity "Pf03088, Pf08450" 71881 ENSMUSG00000033096.7 Apmap 2 0 High A0A0B4J1G0 Low affinity immunoglobulin gamma Fc region receptor IV OS=Mus musculus OX=10090 GN=Fcgr4 PE=1 SV=1 0 23.242 22 6 22 6 249 28.4 8.09 6 4 2 5 10 4 3 5 21943010.63 19165441.5 22224838.38 31833231.75 6 5 5 4 regulation of biological process;response to stimulus cell surface;membrane protein binding;receptor activity;signal transducer activity "Pf00047, Pf07679, Pf07686, Pf13895, Pf13927" 246256 ENSMUSG00000059089.4 Fcgr4 1 Role of phospholipids in phagocytosis; Post-translational modification: synthesis of GPI-anchored proteins; Neutrophil degranulation; Regulation of actin dynamics for phagocytic cup formation; FCGR activation Staphylococcus aureus infection; Tuberculosis; Osteoclast differentiation; Phagosome; Natural killer cell mediated cytotoxicity; Systemic lupus erythematosus; Leishmaniasis 0 High Q8BJ56 Patatin-like phospholipase domain-containing protein 2 OS=Mus musculus OX=10090 GN=Pnpla2 PE=1 SV=1 0 69.938 37 14 22 14 486 53.6 6.46 1 14 1 21 1419377.898 429809.4688 142997702.5 3 1 11 cell organization and biogenesis;metabolic process;regulation of biological process cytosol;membrane catalytic activity;protein binding Pf01734 66853 ENSMUSG00000025509.15 Pnpla2 7 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Acyl chain remodeling of DAG and TAG Regulation of lipolysis in adipocytes; Metabolic pathways; Glycerolipid metabolism 0 High Q9Z2K1 "Keratin, type I cytoskeletal 16 OS=Mus musculus OX=10090 GN=Krt16 PE=1 SV=3" 0 23.212 16 7 22 2 469 51.6 5.2 3 7 2 1 5 9 5 3 4718855 1 cell differentiation;cell organization and biogenesis;cellular component movement;defense response;regulation of biological process;response to stimulus cytoskeleton;nucleus protein binding;structural molecule activity "Pf00038, Pf13514" 16666 ENSMUSG00000053797.10 Krt16 11 Formation of the cornified envelope 0 High Q925U4 ER degradation-enhancing alpha-mannosidase-like protein 1 OS=Mus musculus OX=10090 GN=Edem1 PE=1 SV=1 0 66.003 35 15 21 15 652 73.7 6.15 15 21 3610213.75 4873297.375 151815170.5 1 2 10 metabolic process;response to stimulus endoplasmic reticulum;membrane catalytic activity;metal ion binding;protein binding Pf01532 192193 ENSMUSG00000030104.9 Edem1 6 ER Quality Control Compartment (ERQC) Protein processing in endoplasmic reticulum 0 High O09164 Extracellular superoxide dismutase [Cu-Zn] OS=Mus musculus OX=10090 GN=Sod3 PE=1 SV=1 0 52.125 36 8 21 8 251 27.4 6.84 8 21 506971.5313 6163116 186402524.5 1 2 8 metabolic process;response to stimulus cytoplasm;extracellular;nucleus;organelle lumen antioxidant activity;catalytic activity;metal ion binding;protein binding Pf00080 20657 ENSMUSG00000072941.5 Sod3 5 Detoxification of Reactive Oxygen Species 0 High Q3THW5 Histone H2A.V OS=Mus musculus OX=10090 GN=H2az2 PE=1 SV=3 0 8.641 23 3 21 1 128 13.5 10.58 3 2 2 2 8 4 5 4 743314.6875 1 regulation of biological process chromosome;nucleus DNA binding;protein binding Pf00125 77605 ENSMUSG00000041126.16 H2afv 11 Meiotic Recombination; Mus musculus biological processes; NoRC negatively regulates rRNA expression; Meiotic Synapsis Alcoholism; Systemic lupus erythematosus 0 High A0A075B5R7 Immunoglobulin heavy variable 14-2 (Fragment) OS=Mus musculus OX=10090 GN=Ighv14-2 PE=4 SV=1 0 12.621 32 5 21 2 117 13 6.04 5 3 4 2 9 4 6 2 58607412.25 50526190.5 65351428 52370960.75 5 3 4 3 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding "Pf00047, Pf07686" ENSMUSG00000095583.1 LOC674140 12 3 High P99029 "Peroxiredoxin-5, mitochondrial OS=Mus musculus OX=10090 GN=Prdx5 PE=1 SV=2" 0 24.105 43 7 21 7 210 21.9 8.85 5 3 4 2 7 4 6 4 28393161.63 13166724.25 19809701.63 18986521.5 7 5 5 5 cell death;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;mitochondrion;nucleus;organelle lumen antioxidant activity;catalytic activity;DNA binding;enzyme regulator activity;protein binding "Pf00578, Pf08534" 54683 ENSMUSG00000024953.16 Prdx5 19 Detoxification of Reactive Oxygen Species; TP53 Regulates Metabolic Genes Peroxisome 0 High O54784 Death-associated protein kinase 3 OS=Mus musculus OX=10090 GN=Dapk3 PE=1 SV=1 0 31.054 24 11 21 11 448 51.4 8.7 7 7 5 8 7 6 1087559.719 43719399.63 53836301.5 41126433 2 8 8 6 cell death;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus chromosome;cytoplasm;cytoskeleton;membrane;nucleus catalytic activity;nucleotide binding;protein binding "Pf00069, Pf06293, Pf07714" 13144 ENSMUSG00000034974.13 Dapk3 10 Pathways in cancer; Bladder cancer 0 High A0A0A6YX66 Immunoglobulin heavy variable V1-20 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-20 PE=4 SV=1 0 18.744 37 4 21 2 117 13.1 8.43 3 2 1 2 9 5 5 2 12037431.25 1119580.5 1582901.25 3 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000095761.6 LOC672918 12 0 High P62855 40S ribosomal protein S26 OS=Mus musculus OX=10090 GN=Rps26 PE=1 SV=3 0 21.583 50 5 21 5 115 13 11 4 4 4 5 7 9 6620764.563 76775060 121351926.6 132351145.5 4 5 5 4 metabolic process;regulation of biological process membrane;ribosome protein binding;RNA binding;structural molecule activity Pf01283 27370; 100042812 ENSMUSG00000025362.6 Rps26; Rps26-ps1 10; 8 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High Q8BJD1 Inter-alpha-trypsin inhibitor heavy chain H5 OS=Mus musculus OX=10090 GN=Itih5 PE=1 SV=1 0 37.684 17 13 21 13 952 106.7 8.16 7 1 8 11 1 9 16112054.53 6908105.625 5199828.125 44929387.38 9 2 2 8 metabolic process;regulation of biological process extracellular enzyme regulator activity "Pf00092, Pf06668, Pf08487, Pf10138, Pf13519, Pf13768" 209378 ENSMUSG00000025780.7 Itih5 2 0 High Q6ZQI3 Malectin OS=Mus musculus OX=10090 GN=Mlec PE=1 SV=2 0 40.91 41 11 21 11 291 32.3 6.05 11 21 256526197.5 12 metabolic process endoplasmic reticulum;membrane protein binding Pf11721 109154 ENSMUSG00000048578.11 Mlec 5 N-glycan trimming in the ER and Calnexin/Calreticulin cycle; Neutrophil degranulation 0 High E9Q4M2 Hormone-sensitive lipase OS=Mus musculus OX=10090 GN=Lipe PE=1 SV=1 0 65.411 22 18 21 18 1072 117.2 6.83 1 18 1 20 2068854.828 6431674.625 3947633 95290671.5 5 5 2 12 metabolic process cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;protein binding;RNA binding "Pf06350, Pf07859, Pf10340, Pf12695" 16890 ENSMUSG00000003123.15 Lipe 7 0 High A0A075B5R4 Immunoglobulin heavy variable 14-1 (Fragment) OS=Mus musculus OX=10090 GN=Ighv14-1 PE=4 SV=1 0 17.8 38 5 20 1 117 13 4.93 4 2 4 3 9 3 5 3 12141191.13 7508085.75 9957666.25 7227544 2 2 2 2 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding "Pf00047, Pf07686" ENSMUSG00000094509.1 12 1 High Q02788 Collagen alpha-2(VI) chain OS=Mus musculus OX=10090 GN=Col6a2 PE=1 SV=3 0 32.273 10 8 20 8 1034 110.3 6.42 8 2 4 14 2 4 32678152.75 18184386.75 25164209.5 8 7 7 cell organization and biogenesis;response to stimulus extracellular;membrane "Pf00092, Pf01391, Pf13519" 12834 ENSMUSG00000020241.13 Col6a2 10 ECM proteoglycans; Collagen chain trimerization; Integrin cell surface interactions; NCAM1 interactions; Collagen degradation; Signaling by PDGF; Assembly of collagen fibrils and other multimeric structures Focal adhesion; Protein digestion and absorption; ECM-receptor interaction; PI3K-Akt signaling pathway 0 High G3X9M0 "28S ribosomal protein S29, mitochondrial OS=Mus musculus OX=10090 GN=Dap3 PE=1 SV=1" 0 28.33 23 7 20 7 396 45.3 9.11 1 4 6 6 1 6 7 6 790427.6563 16507082.13 25277705.38 25623962.25 2 5 6 6 cell death;cell organization and biogenesis mitochondrion;organelle lumen;ribosome RNA binding;structural molecule activity "Pf05673, Pf10236" 65111 ENSMUSG00000068921.14 Dap3 3 0 High Q80XR6 Heterogeneous nuclear ribonucleoprotein A/B OS=Mus musculus OX=10090 GN=Hnrnpab PE=1 SV=1 0 23.027 24 8 20 7 311 33.8 5.83 6 2 3 3 9 2 5 4 16119125.88 13879331.13 12298359.75 14537201.5 5 4 4 4 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;nucleus DNA binding;protein binding;RNA binding "Pf00076, Pf08143, Pf13893, Pf14259" 15384 ENSMUSG00000020358.17 Hnrnpab 11 0 High Z4YKM2 "CDGSH iron-sulfur domain-containing protein 3, mitochondrial OS=Mus musculus OX=10090 GN=Cisd3 PE=1 SV=1" 0 33.184 58 7 20 7 115 13.1 9.83 1 2 2 7 1 2 3 14 4773077.75 9245277.5 20033113.88 95927224.5 4 3 5 7 mitochondrion metal ion binding Pf09360 217149 ENSMUSG00000078695.8 Cisd3 11 0 High A0A075B5S2 Immunoglobulin heavy variable 7-1 (Fragment) OS=Mus musculus OX=10090 GN=Ighv7-1 PE=1 SV=2 0 16.481 40 5 20 5 121 13.6 8.29 5 4 3 3 7 5 5 3 59829397.25 34117842 33252459.75 16245446.5 5 4 4 3 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000076665.4 LOC674141 12 0 High C0HK80 Adipocyte-related X-chromosome expressed sequence 2 OS=Mus musculus OX=10090 GN=Arxes2 PE=1 SV=1 0 28.509 40 8 20 8 180 20.1 9.6 8 20 1078861.406 531621743 2 8 cell differentiation;metabolic process;transport endoplasmic reticulum;membrane catalytic activity Pf04573 76219; 76976 ENSMUSG00000048040.8; ENSMUSG00000048355.2 Arxes1; Arxes2 X Protein export 0 High P01899 "H-2 class I histocompatibility antigen, D-B alpha chain OS=Mus musculus OX=10090 GN=H2-D1 PE=1 SV=2" 0 38.833 38 12 20 6 362 40.8 6.73 12 20 449254.5176 2197565.396 20806.10352 251160939 3 2 1 11 regulation of biological process;response to stimulus cell surface;endoplasmic reticulum;Golgi;membrane protein binding;RNA binding "Pf00129, Pf06623, Pf07654, Pf08205" 14964 ENSMUSG00000073411.11 H2-D1 17 Endocytosis; Herpes simplex infection; Allograft rejection; Epstein-Barr virus infection; Cell adhesion molecules (CAMs); HTLV-I infection; Phagosome; Graft-versus-host disease; Viral myocarditis; Antigen processing and presentation; Type I diabetes mellitus; Natural killer cell mediated cytotoxicity; Autoimmune thyroid disease; Viral carcinogenesis 6 High A0A0A0MQ68 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Gcdh PE=1 SV=1" 0 27.089 27 9 20 9 447 49.5 8.72 7 4 2 3 10 5 2 3 17957416 20339330.5 24239028.25 35571790 5 5 6 5 metabolic process membrane;mitochondrion catalytic activity;nucleotide binding "Pf00441, Pf02770, Pf02771, Pf08028" 270076 ENSMUSG00000003809.14 Gcdh 8 Tryptophan metabolism; Metabolic pathways; Lysine degradation; Fatty acid degradation 0 High Q9Z2X1 Heterogeneous nuclear ribonucleoprotein F OS=Mus musculus OX=10090 GN=Hnrnpf PE=1 SV=3 0 33.586 25 7 20 4 415 45.7 5.49 4 3 3 5 6 4 4 6 3177245.75 6878235.5 7178940 10633050.5 2 2 2 2 metabolic process;regulation of biological process cytosol;membrane;nucleus;spliceosomal complex protein binding;RNA binding "Pf00076, Pf08080, Pf14259" 98758 ENSMUSG00000042079.13 Hnrnpf 6 mRNA Splicing - Major Pathway; FGFR2 alternative splicing 0 High P97807 "Fumarate hydratase, mitochondrial OS=Mus musculus OX=10090 GN=Fh PE=1 SV=3" 0 50.079 33 9 20 9 507 54.3 9.04 6 3 5 3 9 3 5 3 17434949.44 14653395.19 14930839.06 31496418.38 6 4 5 7 metabolic process cytoplasm;mitochondrion catalytic activity "Pf00206, Pf10415" 14194 ENSMUSG00000026526.14 Fh1 1 Citric acid cycle (TCA cycle) Pyruvate metabolism; Citrate cycle (TCA cycle); Metabolic pathways; Pathways in cancer; Renal cell carcinoma; Carbon metabolism 0 High O70571 "[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial OS=Mus musculus OX=10090 GN=Pdk4 PE=1 SV=1" 0 33.287 32 11 20 11 412 46.6 7.08 4 2 1 10 5 2 1 12 5560208.188 3463140.5 6838310.75 55543153 7 2 2 8 cell communication;metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf02518, Pf10436" 27273 ENSMUSG00000019577.6 Pdk4 6 Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid 0 High P35979 60S ribosomal protein L12 OS=Mus musculus OX=10090 GN=Rpl12 PE=1 SV=2 0 33.322 50 6 20 6 165 17.8 9.42 2 2 3 5 4 5 5 6 7594875.219 29475266 24867703.88 44164461.88 5 6 4 6 cell organization and biogenesis;metabolic process cytoplasm;membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity "Pf00298, Pf03946" 269261 ENSMUSG00000038900.17 Rpl12 2 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High P49312 Heterogeneous nuclear ribonucleoprotein A1 OS=Mus musculus OX=10090 GN=Hnrnpa1 PE=1 SV=2 0 43.017 27 8 20 5 320 34.2 9.23 5 4 4 2 6 5 4 5 6792424 11486108.75 7470122.5 6493385 4 2 2 2 metabolic process;transport cytoplasm;nucleus;spliceosomal complex DNA binding;RNA binding "Pf00076, Pf13893, Pf14259" 15382 ENSMUSG00000046434.15 Hnrnpa1 15 mRNA Splicing - Major Pathway; FGFR2 alternative splicing Spliceosome 0 High E9Q0F0 Keratin 78 OS=Mus musculus OX=10090 GN=Krt78 PE=1 SV=1 0 12.209 1 2 20 2 1068 112.2 7.97 2 2 1 2 6 3 2 9 60107610 36555881.5 49797629.5 352741816 3 3 3 3 cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;transport cytoskeleton;Golgi;membrane catalytic activity;motor activity;protein binding;structural molecule activity;transporter activity "Pf00038, Pf01576, Pf02050, Pf02321, Pf02403, Pf03280, Pf03938, Pf04111, Pf04156, Pf04740, Pf04977, Pf05008, Pf05103, Pf05335, Pf05483, Pf05557, Pf05622, Pf05642, Pf05667, Pf05911, Pf06013, Pf06133, Pf06160, Pf06810, Pf07321, Pf07926, Pf08614, Pf09606, Pf09726, Pf09731, Pf09755, Pf11559, Pf11932, Pf12128, Pf12325, Pf12329, Pf12795, Pf13514, Pf13851, Pf14362, Pf15070, Pf15397" 332131 ENSMUSG00000050463.8 Krt78 15 Formation of the cornified envelope 0 High Q60994 Adiponectin OS=Mus musculus OX=10090 GN=Adipoq PE=1 SV=2 0 33.666 30 7 20 7 247 26.8 5.57 2 7 2 18 1012408.344 829665.6875 271127277.6 2 1 7 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cell surface;endoplasmic reticulum;extracellular protein binding "Pf00386, Pf01391" 11450 ENSMUSG00000022878.5 Adipoq 16 AMPK inhibits chREBP transcriptional activation activity PPAR signaling pathway; Type II diabetes mellitus; Longevity regulating pathway; Non-alcoholic fatty liver disease (NAFLD); Adipocytokine signaling pathway; AMPK signaling pathway 0 High Q9CPQ1 Cytochrome c oxidase subunit 6C OS=Mus musculus OX=10090 GN=Cox6c PE=1 SV=3 0 15.35 63 6 20 6 76 8.5 10.14 4 4 2 6 5 5 2 8 5551783.125 19364633.25 13057184.38 48815283.5 6 5 5 6 Met-loss+Acetyl [N-Term] metabolic process;transport membrane;mitochondrion catalytic activity;transporter activity Pf02937 12864 ENSMUSG00000014313.14 Cox6c 15 Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 High Q9EPR2 Group XIIA secretory phospholipase A2 OS=Mus musculus OX=10090 GN=Pla2g12a PE=1 SV=2 0 79.09 65 8 20 8 192 21.3 7.15 8 20 225070.5156 219714277.5 1 8 metabolic process;transport cytoplasm;endoplasmic reticulum;extracellular;Golgi catalytic activity;metal ion binding Pf06951 66350 ENSMUSG00000027999.15 Pla2g12a 3 Acyl chain remodelling of PI; Acyl chain remodelling of PG; Acyl chain remodelling of PC; Synthesis of PA; Acyl chain remodelling of PS; Acyl chain remodelling of PE Pancreatic secretion; Ras signaling pathway; Fat digestion and absorption; Metabolic pathways; Linoleic acid metabolism; Ether lipid metabolism; Glycerophospholipid metabolism; alpha-Linolenic acid metabolism; Vascular smooth muscle contraction; Arachidonic acid metabolism 0 High A0A140T8P6 Immunoglobulin kappa variable 12-46 (Fragment) OS=Mus musculus OX=10090 GN=Igkv12-46 PE=1 SV=2 0 19.699 41 3 20 2 115 12.6 5.91 3 2 3 3 9 3 4 4 9354524.5 3177016.5 11864941 7942314 2 1 2 2 protein binding "Pf00047, Pf07679, Pf07686, Pf13895" 692245 ENSMUSG00000076564.2 Igkv12-46 6 0 High P18531 Ig heavy chain V region 3-6 OS=Mus musculus OX=10090 GN=Ighv3-6 PE=1 SV=1 0 12.783 22 3 20 2 116 13.1 8.78 3 3 3 1 8 3 8 1 33875799.59 17601382.5 41955905.25 20264081.38 4 3 3 3 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 780829 ENSMUSG00000076672.7 Gm16932; Ighv3-6 12 Regulation of Complement cascade; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Cell surface interactions at the vascular wall; FCERI mediated NF-kB activation; Role of LAT2/NTAL/LAB on calcium mobilization; Role of phospholipids in phagocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR activation; Classical antibody-mediated complement activation; FCERI mediated Ca+2 mobilization; FCERI mediated MAPK activation; CD22 mediated BCR regulation; Scavenging of heme from plasma 2 High P18528 Ig heavy chain V region 6.96 OS=Mus musculus OX=10090 PE=4 SV=1 0 28.34 31 2 20 1 98 11 7.93 2 2 2 1 6 5 6 3 48627432 29922121 66196537 26430457.75 1 1 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 777688 Gm16971; Ighv5-4 12 0 High Q9CZX8 40S ribosomal protein S19 OS=Mus musculus OX=10090 GN=Rps19 PE=1 SV=3 0 16.96 39 6 19 6 145 16.1 10.4 4 4 4 4 5 5 5 4 5353185.625 21025247.38 18386093.25 33995970.75 5 3 5 4 cell differentiation;cell organization and biogenesis;cellular component movement;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;ribosome protein binding;RNA binding;structural molecule activity Pf01090 20085 ENSMUSG00000040952.16 Rps19 7 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High P14211 Calreticulin OS=Mus musculus OX=10090 GN=Calr PE=1 SV=1 0 38.084 40 12 19 12 416 48 4.49 12 19 575025.625 1176285 107600786.5 1 1 10 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;cytosol;endoplasmic reticulum;extracellular;Golgi;membrane;nucleus;organelle lumen metal ion binding;protein binding;RNA binding Pf00262 12317 ENSMUSG00000003814.8 Calr 8 "Calnexin/calreticulin cycle; Scavenging by Class A Receptors; ER-Phagosome pathway; Antigen Presentation: Folding, assembly and peptide loading of class I MHC" Chagas disease (American trypanosomiasis); HTLV-I infection; Phagosome; Antigen processing and presentation; Protein processing in endoplasmic reticulum 0 High A0A0R4J0Z1 Protein disulfide-isomerase A4 OS=Mus musculus OX=10090 GN=Pdia4 PE=1 SV=1 0 47.84 23 13 19 13 641 72.3 5.22 13 19 57247.85156 1170044.875 74804657.75 1 1 8 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cell surface;endoplasmic reticulum;organelle lumen catalytic activity;metal ion binding;RNA binding "Pf00085, Pf01216, Pf13098, Pf13848, Pf13905" 12304 ENSMUSG00000025823.9 Pdia4 6 Thyroid hormone synthesis; Protein processing in endoplasmic reticulum 0 High Q8K297 Procollagen galactosyltransferase 1 OS=Mus musculus OX=10090 GN=Colgalt1 PE=1 SV=2 0 54.309 20 12 19 12 617 71 7.28 1 12 1 18 3959735 1265407 154732501.5 6 1 11 endoplasmic reticulum;membrane;organelle lumen catalytic activity Pf01755 234407 ENSMUSG00000034807.9 Glt25d1; Colgalt1 8 Collagen biosynthesis and modifying enzymes Lysine degradation; Other types of O-glycan biosynthesis 0 High P01642 Ig kappa chain V-V region L7 (Fragment) OS=Mus musculus OX=10090 GN=Gm10881 PE=1 SV=1 0 16.081 18 2 19 2 115 12.6 5.94 2 2 2 2 6 4 6 3 32822300 23035894.88 36349877.5 27828082 2 2 2 2 response to stimulus "Pf00047, Pf07679, Pf07686" 619846; 434037 ENSMUSG00000076563.2 Igkv5-48; Igkv12-47 6 0 High G3UX26 Outer mitochondrial membrane protein porin 2 OS=Mus musculus OX=10090 GN=Vdac2 PE=1 SV=1 0 38.808 43 10 19 10 283 30.4 7.58 5 1 3 8 6 1 3 9 8035590.063 10694179.63 15962881 76811148.5 6 3 5 7 transport membrane transporter activity Pf01459 ENSMUSG00000021771.13 14 0 High Q8VED5 "Keratin, type II cytoskeletal 79 OS=Mus musculus OX=10090 GN=Krt79 PE=1 SV=2" 0 15.988 8 6 19 1 531 57.5 7.69 3 4 2 4 6 5 3 5 21182834 65000300 25131594 51943016 1 1 1 1 catalytic activity;motor activity;protein binding;structural molecule activity "Pf00038, Pf01576, Pf13166" 223917 ENSMUSG00000061397.7 Krt79 15 Formation of the cornified envelope 0 High Q9ESP1 Stromal cell-derived factor 2-like protein 1 OS=Mus musculus OX=10090 GN=Sdf2l1 PE=1 SV=2 0 66.814 75 11 19 11 221 23.6 7.42 11 19 312802312 8 metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;membrane;organelle lumen catalytic activity;protein binding Pf02815 64136 ENSMUSG00000022769.7 Sdf2l1 16 0 High D3YXK2 Scaffold attachment factor B1 OS=Mus musculus OX=10090 GN=Safb PE=1 SV=2 0 35.936 17 9 19 4 937 105 5.35 8 5 1 13 5 1 15683496.69 16412657.38 9845758.25 16360136.25 7 4 3 3 metabolic process;regulation of biological process;response to stimulus nucleus DNA binding;protein binding;RNA binding "Pf00076, Pf02037, Pf13893, Pf14259" 224903 ENSMUSG00000071054.12 Safb 17 4 High Q8VIJ6 "Splicing factor, proline- and glutamine-rich OS=Mus musculus OX=10090 GN=Sfpq PE=1 SV=1" 0 30.812 20 11 19 10 699 75.4 9.44 10 2 2 1 13 2 3 1 33731579.25 12401359.13 26534218 22886553.25 10 5 8 6 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus chromosome;cytoplasm;nucleus DNA binding;protein binding;RNA binding "Pf00076, Pf08075, Pf13893, Pf14259" 71514 ENSMUSG00000028820.13 Sfpq 4 PTK6 Regulates Proteins Involved in RNA Processing 1 High P62264 40S ribosomal protein S14 OS=Mus musculus OX=10090 GN=Rps14 PE=1 SV=3 0 36.516 43 9 18 9 151 16.3 10.05 3 1 2 8 3 1 3 11 8910376.031 14962190.88 24912040.13 93036143 8 5 7 9 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process membrane;mitochondrion;ribosome RNA binding;structural molecule activity;translation regulator activity Pf00411 20044 ENSMUSG00000024608.10 Rps14 18 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High Q9R0E1 Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 OS=Mus musculus OX=10090 GN=Plod3 PE=1 SV=1 0 41.312 16 10 18 9 741 84.9 6.23 2 10 2 16 3798573.75 106265847 6 8 cell organization and biogenesis;metabolic process;response to stimulus endoplasmic reticulum;Golgi;membrane catalytic activity;metal ion binding Pf03171 26433 ENSMUSG00000004846.10 Plod3 5 Collagen biosynthesis and modifying enzymes Lysine degradation; Other types of O-glycan biosynthesis 1 High Q62261 "Spectrin beta chain, non-erythrocytic 1 OS=Mus musculus OX=10090 GN=Sptbn1 PE=1 SV=2" 0 42.726 8 14 18 14 2363 274.1 5.58 14 18 16529068.81 1373475.25 13 1 cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;membrane;nucleus protein binding;RNA binding;structural molecule activity "Pf00169, Pf00307, Pf00435, Pf11971, Pf12128, Pf15410" 20742 ENSMUSG00000020315.18 Spnb2; Sptbn1 11 RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Interaction between L1 and Ankyrins; COPI-mediated anterograde transport; Interleukin-20 family signaling Tight junction 0 High A0A0G2JDE1 Immunoglobulin heavy variable V8-12 (Fragment) OS=Mus musculus OX=10090 GN=Ighv8-12 PE=1 SV=1 0 18.828 31 3 18 2 119 13.3 9.17 3 1 3 1 7 2 8 1 29756317.25 13088358.88 58035835.88 2400807.25 3 1 3 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000076731.3 12 Regulation of Complement cascade; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Cell surface interactions at the vascular wall; FCERI mediated NF-kB activation; Role of LAT2/NTAL/LAB on calcium mobilization; Role of phospholipids in phagocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR activation; Classical antibody-mediated complement activation; FCERI mediated Ca+2 mobilization; FCERI mediated MAPK activation; CD22 mediated BCR regulation; Scavenging of heme from plasma 1 High Q9D6Y9 "1,4-alpha-glucan-branching enzyme OS=Mus musculus OX=10090 GN=Gbe1 PE=1 SV=1" 0 39.018 17 9 18 9 702 80.3 6.43 9 4 14 4 21584725.13 16319727.63 20225327.88 7640099.5 7 6 6 4 metabolic process catalytic activity "Pf00128, Pf02806, Pf02922" 74185 ENSMUSG00000022707.16 Gbe1 16 Glycogen synthesis Metabolic pathways; Starch and sucrose metabolism 0 High A0A140T8P1 Immunoglobulin kappa variable 6-14 (Fragment) OS=Mus musculus OX=10090 GN=Igkv6-14 PE=4 SV=2 0 12.792 29 3 18 2 115 12.8 6.51 3 1 2 1 10 1 5 2 16870290.75 2448907 18380637 5373124.5 2 1 2 1 structural molecule activity "Pf00047, Pf01410, Pf07679, Pf07686" 667881 ENSMUSG00000096844.1 Igkv6-14 6 0 High Q99KV1 DnaJ homolog subfamily B member 11 OS=Mus musculus OX=10090 GN=Dnajb11 PE=1 SV=1 0 39.363 28 10 18 10 358 40.5 6.32 10 18 363470.8125 120832452.8 1 10 metabolic process;regulation of biological process cytoplasm;endoplasmic reticulum;membrane;nucleus;organelle lumen protein binding "Pf00226, Pf01556" 67838 ENSMUSG00000004460.16 Dnajb11 16 Protein processing in endoplasmic reticulum 0 High P31324 cAMP-dependent protein kinase type II-beta regulatory subunit OS=Mus musculus OX=10090 GN=Prkar2b PE=1 SV=3 0 53.289 33 11 18 11 416 46.1 4.98 4 1 1 10 4 1 1 12 6886375.188 1665969.125 3504961.375 64428862.75 7 1 2 9 metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane enzyme regulator activity;nucleotide binding;protein binding "Pf00027, Pf02197" 19088 ENSMUSG00000002997.15 Prkar2b 12 PKA activation; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Signaling by GPCR; Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes; PKA activation in glucagon signalling; DARPP-32 events; Hedgehog 'off' state; Vasopressin regulates renal water homeostasis via Aquaporins; Factors involved in megakaryocyte development and platelet production Insulin signaling pathway 0 High A0A075B5K2 Immunoglobulin kappa chain variable 9-124 OS=Mus musculus OX=10090 GN=Igkv9-124 PE=1 SV=7 0 31.621 58 5 18 5 95 10.4 5.01 5 2 4 1 9 2 5 2 36531878.75 12839647.88 38964840.75 11811687.5 5 3 4 2 "Pf00047, Pf07679, Pf07686" ENSMUSG00000096632.2 6 0 High Q5SWT3 Solute carrier family 25 member 35 OS=Mus musculus OX=10090 GN=Slc25a35 PE=1 SV=2 0 56.697 46 11 18 11 300 32.6 9.52 1 11 1 17 1967296.844 1624718.25 2357686 68117072.47 3 1 1 8 transport membrane;mitochondrion transporter activity Pf00153 71998 ENSMUSG00000018740.14 Slc25a35 11 0 High Q9CZ13 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Mus musculus OX=10090 GN=Uqcrc1 PE=1 SV=2" 0 34.94 25 7 18 7 480 52.8 6.21 3 6 2 5 4 7 2 5 6376057.656 19673448.38 7646468.875 14408502.75 4 5 3 3 metabolic process;response to stimulus;transport cytosol;membrane;mitochondrion catalytic activity;metal ion binding;protein binding "Pf00675, Pf05193, Pf08367" 22273 ENSMUSG00000025651.14; ENSMUSG00000107235.3 Uqcrc1 9; CHR_MG117_PATCH Respiratory electron transport Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 High Q8C0C7 Phenylalanine--tRNA ligase alpha subunit OS=Mus musculus OX=10090 GN=Farsa PE=1 SV=1 0 29.958 23 10 18 10 508 57.6 8.28 10 1 2 3 10 1 3 4 8877981.688 2629635.125 2263455.125 21263121 8 2 2 6 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process cytoplasm;membrane catalytic activity;nucleotide binding;RNA binding "Pf00152, Pf01409, Pf08279" 66590 ENSMUSG00000003808.18 Farsa 8 Aminoacyl-tRNA biosynthesis 0 High P01898 "H-2 class I histocompatibility antigen, Q10 alpha chain OS=Mus musculus OX=10090 GN=H2-Q10 PE=1 SV=3" 0 42.342 44 11 18 8 325 37.2 5.25 11 18 46843.40625 126570324.3 1 7 cell surface;endoplasmic reticulum;Golgi;membrane protein binding;RNA binding "Pf00129, Pf07654, Pf08205" 15007 ENSMUSG00000067235.14 H2-Q10 17 Endocytosis; Herpes simplex infection; Allograft rejection; Epstein-Barr virus infection; Cell adhesion molecules (CAMs); HTLV-I infection; Phagosome; Graft-versus-host disease; Viral myocarditis; Antigen processing and presentation; Type I diabetes mellitus; Autoimmune thyroid disease; Viral carcinogenesis 0 High A0A075B5L1 Immunoglobulin kappa variable 10-94 (Fragment) OS=Mus musculus OX=10090 GN=Igkv10-94 PE=4 SV=7 0 17.621 37 2 18 2 115 12.6 5.9 1 1 2 1 7 2 6 3 42232677 16395313.88 45310635.25 16827000 2 2 2 1 response to stimulus "Pf00047, Pf07679, Pf07686" ENSMUSG00000096490.1 6 0 High A0A0B4J1J6 Immunoglobulin heavy variable 10-1 (Fragment) OS=Mus musculus OX=10090 GN=Ighv10-1 PE=4 SV=1 0 18.539 28 4 18 2 119 13.5 8.59 4 2 4 2 7 3 6 2 21788575.75 12638433 33486178 37894760.25 4 3 3 3 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding 16050 ENSMUSG00000095981.1 Igh-V10 12 2 High O55143 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 OS=Mus musculus OX=10090 GN=Atp2a2 PE=1 SV=2 0 48.009 17 14 17 7 1044 114.8 5.34 14 17 697567.625 4260244 6301642.5 67940549.75 3 1 1 8 cell organization and biogenesis;cellular homeostasis;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;membrane catalytic activity;metal ion binding;nucleotide binding;protein binding;transporter activity "Pf00122, Pf00689, Pf00690, Pf00702, Pf08282, Pf12710, Pf13246" 11938 ENSMUSG00000029467.15 Atp2a2 5 Ion transport by P-type ATPases; Ion homeostasis; Reduction of cytosolic Ca++ levels Hypertrophic cardiomyopathy (HCM); Pancreatic secretion; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Dilated cardiomyopathy; Thyroid hormone signaling pathway; cGMP-PKG signaling pathway; Calcium signaling pathway; Alzheimer's disease; Cardiac muscle contraction; cAMP signaling pathway; Adrenergic signaling in cardiomyocytes 5 High P01801 Ig heavy chain V-III region J606 OS=Mus musculus OX=10090 PE=1 SV=1 0 37.178 47 6 17 3 115 12.8 7.12 4 3 5 2 4 6 5 2 66131344.25 40431345.5 46346512 30895704.13 5 4 4 4 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 238427 Ighv6-6 12 4 High A2AGH8 Mediator of RNA polymerase II transcription subunit 12 OS=Mus musculus OX=10090 GN=Med12 PE=1 SV=1 0 45.614 10 15 17 15 2157 240.7 7.17 14 1 16 1 13500826.19 11506807.38 2241638 5866557.75 12 6 1 2 Met-loss+Acetyl [N-Term] metabolic process;regulation of biological process;response to stimulus membrane;nucleus catalytic activity;DNA binding;protein binding;receptor activity "Pf09497, Pf09606, Pf12144, Pf12145" 59024 ENSMUSG00000079487.11 Med12 X 0 High Q8C0T5 Signal-induced proliferation-associated 1-like protein 1 OS=Mus musculus OX=10090 GN=Sipa1l1 PE=1 SV=2 0 30.286 8 8 17 8 1782 196.9 8.13 7 5 2 10 5 2 294562.0625 33875785 28520212 17913430 1 6 5 4 cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane enzyme regulator activity;protein binding "Pf00595, Pf02145, Pf11881" 217692 ENSMUSG00000042700.15 Sipa1l1 12 Rap1 signaling pathway 0 High Q3TQC7 Ectonucleoside triphosphate diphosphohydrolase 5 OS=Mus musculus OX=10090 GN=Entpd5 PE=1 SV=1 0 45.156 33 12 17 12 452 49.8 5.47 12 17 84222233.5 7 cell growth;cell proliferation;metabolic process;regulation of biological process endoplasmic reticulum;extracellular;membrane catalytic activity Pf01150 12499 ENSMUSG00000021236.16 Entpd5 12 0 High Q99NB1 "Acetyl-coenzyme A synthetase 2-like, mitochondrial OS=Mus musculus OX=10090 GN=Acss1 PE=1 SV=1" 0 28.047 12 7 17 7 682 74.6 6.98 5 2 4 2 7 3 4 3 6387636.789 5515811.719 6598924.203 74934229.94 8 5 5 6 metabolic process mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf00501, Pf13193" 68738 ENSMUSG00000027452.11 Acss1 2 Ethanol oxidation Pyruvate metabolism; Metabolic pathways; Glycolysis / Gluconeogenesis; Propanoate metabolism; Carbon metabolism 0 High A0A140T8P2 Immunoglobulin kappa variable 6-20 (Fragment) OS=Mus musculus OX=10090 GN=Igkv6-20 PE=4 SV=2 0 9.856 40 4 17 3 115 12.6 5.01 4 3 2 2 7 4 4 2 35263834 21002854.5 15203151 15929995 2 2 2 2 "Pf00047, Pf07679, Pf07686, Pf13927" 108024 ENSMUSG00000076587.3 Igkv6-20 6 0 High Q01149 Collagen alpha-2(I) chain OS=Mus musculus OX=10090 GN=Col1a2 PE=1 SV=2 0 12.585 4 6 17 6 1372 129.5 9.19 5 4 5 2 6 4 5 2 31731886.25 35710296 44324904 26106257 6 6 6 5 cell organization and biogenesis;regulation of biological process;response to stimulus endoplasmic reticulum;extracellular metal ion binding;protein binding;structural molecule activity "Pf01391, Pf01410" 12843 ENSMUSG00000029661.16 Col1a2 6 Anchoring fibril formation; ECM proteoglycans; Cell surface interactions at the vascular wall; Platelet Aggregation (Plug Formation); Integrin cell surface interactions; Collagen degradation; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; Crosslinking of collagen fibrils; Collagen chain trimerization; GP1b-IX-V activation signalling; Platelet Adhesion to exposed collagen; MET activates PTK2 signaling; GPVI-mediated activation cascade; Non-integrin membrane-ECM interactions AGE-RAGE signaling pathway in diabetic complications; Focal adhesion; Protein digestion and absorption; Platelet activation; Proteoglycans in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway; Amoebiasis 0 High A0A075B5Q4 Immunoglobulin heavy variable 5-12 (Fragment) OS=Mus musculus OX=10090 GN=Ighv5-12 PE=4 SV=1 0 11.993 31 3 17 1 117 13.1 8.85 3 3 3 1 6 4 6 1 51902874.5 31703668 26034552.25 7767962.125 3 3 3 2 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000095429.1 LOC674114 12 2 High A0A0B4J1J2 Immunoglobulin kappa chain variable 5-43 (Fragment) OS=Mus musculus OX=10090 GN=Igkv5-43 PE=1 SV=1 0 23.051 29 3 17 2 115 12.6 6.51 3 1 2 2 7 1 5 4 144786021.7 58190949.5 130598397.8 98728230.5 4 3 4 3 response to stimulus "Pf00047, Pf07679, Pf07686, Pf13927" 381783 ENSMUSG00000094433.2 Igkv5-43 6 2 High P62830 60S ribosomal protein L23 OS=Mus musculus OX=10090 GN=Rpl23 PE=1 SV=1 0 32.102 46 6 17 6 140 14.9 10.51 2 1 3 6 2 1 4 10 6510610.688 14011160.63 21701619 81684292.63 5 5 4 5 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;ribosome protein binding;RNA binding;structural molecule activity Pf00238 65019; 100044627; 100862455 ENSMUSG00000071415.6 Rpl23; LOC100044627; LOC100862455 11; 17 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q99M87 "DnaJ homolog subfamily A member 3, mitochondrial OS=Mus musculus OX=10090 GN=Dnaja3 PE=1 SV=1" 0 47.082 25 8 17 8 480 52.4 9.22 2 1 1 8 2 1 1 13 14179108.53 7712762.5 11165251.63 81510163.75 6 3 4 6 cell death;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus;organelle lumen enzyme regulator activity;metal ion binding;nucleotide binding;protein binding "Pf00226, Pf00684, Pf01556" 83945 ENSMUSG00000004069.16 Dnaja3 16 Viral carcinogenesis 0 High P17751 Triosephosphate isomerase OS=Mus musculus OX=10090 GN=Tpi1 PE=1 SV=5 0 40.066 50 9 17 9 249 26.7 7.3 8 2 1 5 9 2 1 5 16273135.31 10055945 20162153.38 23804132.5 7 3 5 5 development;metabolic process cytosol;nucleus catalytic activity;protein binding Pf00121 21991 Tpi1 6 0 High P61979 Heterogeneous nuclear ribonucleoprotein K OS=Mus musculus OX=10090 GN=Hnrnpk PE=1 SV=1 0 29.057 23 8 17 8 463 50.9 5.54 4 1 6 4 5 1 7 4 14481175.38 12033156.25 20727464 32590767.75 7 4 5 7 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus;spliceosomal complex DNA binding;protein binding;RNA binding "Pf00013, Pf08067, Pf13014, Pf13083" 15387 ENSMUSG00000021546.17 Hnrnpk 13 mRNA Splicing - Major Pathway Herpes simplex infection; MicroRNAs in cancer; Spliceosome; Viral carcinogenesis 0 High Q6GT24 Peroxiredoxin-6 OS=Mus musculus OX=10090 GN=Prdx6 PE=1 SV=1 0 20.568 30 7 17 7 224 24.8 6.37 6 3 4 1 9 3 4 1 11921674.63 15275976.25 6548086.125 17545044.63 7 7 4 6 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus;vacuole antioxidant activity;catalytic activity;protein binding "Pf00578, Pf08534, Pf10417" 11758 ENSMUSG00000026701.15 Prdx6 1 Neutrophil degranulation; Detoxification of Reactive Oxygen Species Metabolic pathways 0 High Q3TWW8 Serine/arginine-rich splicing factor 6 OS=Mus musculus OX=10090 GN=Srsf6 PE=1 SV=1 0 13.035 15 6 17 4 339 39 11.46 1 2 6 2 2 3 9 3 3694335.5 41068236.25 87668056 45435426 2 6 6 4 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus nucleus protein binding;RNA binding "Pf00076, Pf08777, Pf13893, Pf14259" 67996 ENSMUSG00000016921.14 Srsf6 2 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript Herpes simplex infection; Spliceosome 2 High E9QP99 Golgin subfamily A member 3 OS=Mus musculus OX=10090 GN=Golga3 PE=1 SV=1 0 41.003 13 15 17 15 1487 167.2 5.38 4 13 4 13 4740233.375 34201090.63 7 9 cell differentiation;development;metabolic process;regulation of biological process cytoplasm;cytosol;Golgi;membrane;nucleus protein binding "Pf02463, Pf04111, Pf04156, Pf05557, Pf07888, Pf09726, Pf10186, Pf12128, Pf13166" 269682 ENSMUSG00000029502.14 Golga3 5 0 High H3BKG0 Caveolin-1 OS=Mus musculus OX=10090 GN=Cav1 PE=1 SV=1 0 15.097 47 4 17 4 93 10.4 6.05 1 3 3 4 2 4 6 5 7008142.688 36002285.38 53467958 63195861.25 3 4 4 4 cell differentiation;cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport endoplasmic reticulum;Golgi;membrane enzyme regulator activity;protein binding;structural molecule activity Pf01146 ENSMUSG00000007655.16 6 0 High A0A075B680 Immunoglobulin heavy variable 1-62-2 OS=Mus musculus OX=10090 GN=Ighv1-62-2 PE=4 SV=1 0 26.745 58 4 17 3 100 11.2 8.43 3 1 4 1 7 2 7 1 44675306.19 29183215.75 52240820.75 9441439.5 3 3 4 2 "Pf00047, Pf07686" ENSMUSG00000096078.2; ENSMUSG00000096577.2 12 1 High Q6NVF9 Cleavage and polyadenylation specificity factor subunit 6 OS=Mus musculus OX=10090 GN=Cpsf6 PE=1 SV=1 0 35.554 17 7 17 7 551 59.1 7.15 6 1 3 2 10 1 4 2 19543956.69 4874629.281 22355359.63 13653884.75 5 3 4 4 cell organization and biogenesis;metabolic process membrane;nucleus RNA binding "Pf00076, Pf14259" 432508 ENSMUSG00000055531.12 Cpsf6 10 mRNA surveillance pathway 0 High Q9CZM2 60S ribosomal protein L15 OS=Mus musculus OX=10090 GN=Rpl15 PE=1 SV=4 0 18.44 39 8 17 8 204 24.1 11.62 2 5 3 6 2 6 3 6 26634283.38 53306605.25 119837609.4 536935114.9 3 7 7 7 metabolic process membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity Pf00827 66480 ENSMUSG00000012405.15 Rpl15 14 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High A0A140T8N0 Immunoglobulin kappa chain variable 9-120 (Fragment) OS=Mus musculus OX=10090 GN=Igkv9-120 PE=1 SV=2 0 19.844 32 4 17 4 117 12.8 4.88 3 1 4 1 8 2 5 2 33268651.38 17824389.5 49361736.5 22585163 3 3 3 2 "Pf07679, Pf07686" ENSMUSG00000094872.1 6 0 High A0A075B5M4 Immunoglobulin kappa variable 4-57-1 (Fragment) OS=Mus musculus OX=10090 GN=Igkv4-57-1 PE=4 SV=1 0 17.573 32 3 17 2 119 12.7 7.11 3 1 3 3 8 1 3 5 21974188.88 8628735.75 28542402 13591465.25 3 2 3 3 response to stimulus Pf07686 ENSMUSG00000076555.3 LOC675950 6 1 High Q8BW75 Amine oxidase [flavin-containing] B OS=Mus musculus OX=10090 GN=Maob PE=1 SV=4 0 43.709 25 10 17 10 520 58.5 8.29 10 17 166249.1719 57316927 1 6 metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion catalytic activity;nucleotide binding;protein binding "Pf01593, Pf13450" 109731 ENSMUSG00000040147.14 Maob X Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB "Histidine metabolism; Arginine and proline metabolism; Tryptophan metabolism; Dopaminergic synapse; Drug metabolism - cytochrome P450; Metabolic pathways; Amphetamine addiction; Glycine, serine and threonine metabolism; Cocaine addiction; Alcoholism; Phenylalanine metabolism; Tyrosine metabolism; Serotonergic synapse" 0 High A0A140T8M9 Immunoglobulin kappa chain variable 1-122 (Fragment) OS=Mus musculus OX=10090 GN=Igkv1-122 PE=4 SV=2 0 6.043 17 2 17 1 119 13.1 7.99 1 1 2 1 4 4 6 3 3577838.5 6808526 1 1 Pf07686 434024 ENSMUSG00000095497.2 Igkv1-122 6 0 High Q9CQ69 Cytochrome b-c1 complex subunit 8 OS=Mus musculus OX=10090 GN=Uqcrq PE=1 SV=3 0 22.094 74 5 17 5 82 9.8 10.26 2 2 5 4 2 11 4951431.563 8042340.703 10435147.47 59493143 3 4 4 5 metabolic process;transport membrane;mitochondrion catalytic activity;transporter activity Pf02939 22272 ENSMUSG00000044894.14 Uqcrq 11 Respiratory electron transport Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 High Q8BHD8 Protein-L-isoaspartate O-methyltransferase domain-containing protein 2 OS=Mus musculus OX=10090 GN=Pcmtd2 PE=2 SV=1 0 15.476 17 7 16 7 359 40.7 6.46 7 16 15410349.69 9201894.625 21849399.75 16167079.75 7 2 4 3 metabolic process cytoplasm catalytic activity "Pf01135, Pf12847, Pf13847" 245867 ENSMUSG00000027589.14 Pcmtd2 2 0 High Q91VT4 3-oxoacyl-[acyl-carrier-protein] reductase OS=Mus musculus OX=10090 GN=Cbr4 PE=1 SV=2 0 26.477 29 6 16 6 236 25.4 9.69 3 1 6 3 1 12 6473845.313 5261756.25 10412315.5 104292742 5 2 4 6 cell organization and biogenesis;metabolic process mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf00106, Pf03435, Pf08659, Pf13561" 234309 ENSMUSG00000031641.14 Cbr4 8 Fatty acyl-CoA biosynthesis 0 High A0A0R4J0L1 Beta-galactosidase OS=Mus musculus OX=10090 GN=Glb1l2 PE=1 SV=1 0 56.487 25 14 16 14 652 73.9 7.87 14 16 1401619.688 140749142.8 2 14 metabolic process extracellular;vacuole catalytic activity "Pf01301, Pf02449" 244757 ENSMUSG00000036395.15 Glb1l2 9 0 High P62843 40S ribosomal protein S15 OS=Mus musculus OX=10090 GN=Rps15 PE=1 SV=2 0 29.26 64 5 16 5 145 17 10.39 1 3 4 3 1 6 6 3 2226266.641 16460255.66 19556107 20690707.5 4 4 3 4 cell differentiation;cell organization and biogenesis;metabolic process;transport membrane;ribosome protein binding;RNA binding;structural molecule activity Pf00203 20054 ENSMUSG00000063457.14 Rps15 10 Ribosome 0 High A0A0B4J1I9 Immunoglobulin kappa variable 4-55 (Fragment) OS=Mus musculus OX=10090 GN=Igkv4-55 PE=1 SV=1 0 17.766 27 2 16 1 117 12.7 6.48 2 1 2 2 7 3 4 2 15493649 2342134.5 7766538.5 5039414 1 1 1 1 response to stimulus "Pf00047, Pf07686" 385253 ENSMUSG00000096833.2 Igkv4-55 6 0 High P46412 Glutathione peroxidase 3 OS=Mus musculus OX=10090 GN=Gpx3 PE=1 SV=2 0 19.729 35 7 16 7 226 25.4 8.22 1 7 1 15 1235264.234 159477022 4 7 cell organization and biogenesis;metabolic process;response to stimulus extracellular antioxidant activity;catalytic activity Pf00255 14778 ENSMUSG00000018339.11 Gpx3 11 Detoxification of Reactive Oxygen Species Glutathione metabolism; Thyroid hormone synthesis; Arachidonic acid metabolism 0 High Q8CGK3 "Lon protease homolog, mitochondrial OS=Mus musculus OX=10090 GN=Lonp1 PE=1 SV=2" 0 52.633 19 12 16 12 949 105.8 6.57 4 1 10 4 1 11 5146555.039 5646575.57 45318775 8 6 9 cell organization and biogenesis;metabolic process;response to stimulus cytosol;membrane;mitochondrion;nucleus;organelle lumen catalytic activity;DNA binding;nucleotide binding;protein binding;RNA binding "Pf00004, Pf00910, Pf01695, Pf02190, Pf05362, Pf05496, Pf07724, Pf07726, Pf07728, Pf08298, Pf13173, Pf13191, Pf13207, Pf13401, Pf13541" 74142 ENSMUSG00000041168.9 Lonp1 17 0 High P10605 Cathepsin B OS=Mus musculus OX=10090 GN=Ctsb PE=1 SV=2 0 33.409 29 8 16 8 339 37.3 5.91 2 4 8 2 4 10 2957662.875 10440469.25 22547911.34 3 3 4 cell differentiation;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;extracellular;membrane;mitochondrion;vacuole catalytic activity;protein binding "Pf00112, Pf08127" 13030 ENSMUSG00000021939.7 Ctsb 14 Neutrophil degranulation; Collagen degradation; Trafficking and processing of endosomal TLR NOD-like receptor signaling pathway; Lysosome; Antigen processing and presentation; Renin secretion; Apoptosis 0 High P47963 60S ribosomal protein L13 OS=Mus musculus OX=10090 GN=Rpl13 PE=1 SV=3 0 15.617 36 7 16 7 211 24.3 11.55 3 4 3 3 4 5 3 4 7911637.5 33837714.13 24575895.5 33462927 6 7 5 6 metabolic process membrane;nucleus;ribosome RNA binding;structural molecule activity Pf01294 270106 ENSMUSG00000000740.12 Rpl13 8 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q4ZJN1 Complement C1q and tumor necrosis factor-related protein 9 OS=Mus musculus OX=10090 GN=C1qtnf9 PE=1 SV=1 0 19.412 19 5 16 5 333 34.5 7.91 5 1 2 12 2 2 15974094.69 11144496 9380958.125 3467133.25 5 3 3 1 regulation of biological process;response to stimulus extracellular;membrane protein binding "Pf00229, Pf00386, Pf01391" 239126 ENSMUSG00000071347.3 C1qtnf9 14 0 High A0A0G2JFZ3 Immunoglobulin kappa chain variable 19-93 (Fragment) OS=Mus musculus OX=10090 GN=Igkv19-93 PE=1 SV=4 0 14.958 21 2 16 2 115 12.8 8.29 2 2 2 2 5 4 4 3 36375779 33884554 47408665.75 29043767.5 2 2 2 2 response to stimulus "Pf00047, Pf07679, Pf07686" 692161 ENSMUSG00000098814.2 Igkv19-93 6 0 High P70428 Exostosin-2 OS=Mus musculus OX=10090 GN=Ext2 PE=1 SV=2 0 42.543 21 12 16 12 718 82 6.65 12 16 6013491 2390461 2985280 86882639 4 1 1 9 cell differentiation;metabolic process endoplasmic reticulum;Golgi;membrane catalytic activity;metal ion binding;protein binding "Pf03016, Pf09258" 14043 ENSMUSG00000027198.16 Ext2 2 HS-GAG biosynthesis Metabolic pathways; Glycosaminoglycan biosynthesis - heparan sulfate / heparin 0 High P84244 Histone H3.3 OS=Mus musculus OX=10090 GN=H3-3a PE=1 SV=2 0 15.647 43 5 16 5 136 15.3 11.27 5 1 3 2 10 1 3 2 36043032.75 9357593.438 19365023.81 16462496.5 5 5 5 4 cell differentiation;cell organization and biogenesis;cell proliferation;regulation of biological process;response to stimulus chromosome;nucleus DNA binding;protein binding "Pf00125, Pf15630" 15078; 15081 ENSMUSG00000016559.14; ENSMUSG00000060743.12 H3f3a; H3f3b 1; 11 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Transcriptional regulation by small RNAs; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Oxidative Stress Induced Senescence; Meiotic Recombination; Senescence-Associated Secretory Phenotype (SASP); SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; B-WICH complex positively regulates rRNA expression; RNA Polymerase I Promoter Opening; NoRC negatively regulates rRNA expression; Meiotic Synapsis; Mus musculus biological processes; RNA Polymerase I Chain Elongation; NoRC negatively regulates rRNA expression; Factors involved in megakaryocyte development and platelet production Transcriptional misregulation in cancer; Alcoholism; Systemic lupus erythematosus 0 Medium Q6P5H2 Nestin OS=Mus musculus OX=10090 GN=Nes PE=1 SV=1 0.017 1.342 0 1 16 1 1864 207 4.34 1 1 1 1 4 3 3 6 69214456 47125524 57508364 310252480 1 1 1 1 cell organization and biogenesis;cell proliferation;development;regulation of biological process cytoplasm;cytoskeleton protein binding;structural molecule activity "Pf00038, Pf02463" 18008 ENSMUSG00000004891.16 Nes 3 0 High Q9CQM8 60S ribosomal protein L21 OS=Mus musculus OX=10090 GN=Rpl21 PE=1 SV=1 0 20.266 26 4 16 4 160 18.6 10.49 2 4 3 4 2 5 4 5 4258072.281 20645168.25 19423239.88 30135913.38 3 4 4 4 metabolic process membrane;ribosome protein binding;RNA binding;structural molecule activity Pf01157 19933; 676253; 100503563; 675278 ENSMUSG00000041453.12 Rpl21; Gm14648; Gm10240; Rpl21-ps15 5; X; 15 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High P85094 Isochorismatase domain-containing protein 2A OS=Mus musculus OX=10090 GN=Isoc2a PE=1 SV=1 0 49.73 52 5 16 5 206 22.4 8.02 3 5 1 3 4 8 1 3 6497836.359 11485842.69 1703222 5537077 3 3 1 1 metabolic process;regulation of biological process cytoplasm;mitochondrion;nucleus catalytic activity Pf00857 664994 ENSMUSG00000086784.2 Isoc2a 7 0 High P08249 "Malate dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Mdh2 PE=1 SV=3" 0 23.95 28 9 16 9 338 35.6 8.68 6 8 2 6 8 2 10845187.88 36056397.75 10671269.63 28560205.13 8 7 4 7 metabolic process membrane;mitochondrion;nucleus;organelle lumen catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00056, Pf01073, Pf01118, Pf02866, Pf13460" 17448 ENSMUSG00000019179.10 Mdh2 5 Gluconeogenesis; Citric acid cycle (TCA cycle) Pyruvate metabolism; Citrate cycle (TCA cycle); Metabolic pathways; Cysteine and methionine metabolism; Carbon metabolism; Glyoxylate and dicarboxylate metabolism 0 High Q9CR62 Mitochondrial 2-oxoglutarate/malate carrier protein OS=Mus musculus OX=10090 GN=Slc25a11 PE=1 SV=3 0 27.024 30 9 16 9 314 34.1 9.94 1 1 9 2 1 13 1686118.844 6316476.75 6006921.5 113799564.8 2 2 2 7 Met-loss+Acetyl [N-Term] transport membrane;mitochondrion;nucleus RNA binding;transporter activity Pf00153 67863 ENSMUSG00000014606.14 Slc25a11 11 Gluconeogenesis 0 High Q14C51 "Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Mus musculus OX=10090 GN=Ptcd3 PE=1 SV=2" 0 39.539 19 9 15 9 685 77.7 5.88 5 6 1 6 8 1 2699290.25 13303233.37 9733833.172 15905828.31 3 6 4 5 cell organization and biogenesis;metabolic process;regulation of biological process cytosol;membrane;mitochondrion;ribosome RNA binding "Pf12854, Pf13041" 69956 ENSMUSG00000063884.6 Ptcd3 6 Mitochondrial translation termination; Mitochondrial translation elongation 0 High H7BX88 Carnitine O-acetyltransferase OS=Mus musculus OX=10090 GN=Crat PE=1 SV=1 0 29.304 22 9 15 9 605 68.6 8.07 3 3 1 7 3 3 1 8 2106560 5390626 8158361.625 9460470.5 3 3 3 2 mitochondrion catalytic activity Pf00755 ENSMUSG00000026853.15 2 0 High A0A0G2JFE9 Immunoglobulin heavy variable 1-76 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-76 PE=1 SV=1 0 18.528 33 3 15 3 117 13 9.07 3 2 2 8 5 2 37441122.25 22544386.25 40423128.63 17402544.5 3 3 3 2 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding "Pf00047, Pf07686" ENSMUSG00000093896.2 12 0 High Q9CQX8 "28S ribosomal protein S36, mitochondrial OS=Mus musculus OX=10090 GN=Mrps36 PE=1 SV=1" 0 37.583 71 4 15 4 102 11.1 9.99 4 2 2 1 9 2 3 1 36030847.25 22849898.75 24940817 16771543.13 4 4 4 4 mitochondrion;ribosome Pf10937 66128 ENSMUSG00000061474.11 Mrps36 13 Mitochondrial translation termination; Mitochondrial translation elongation 0 High F7AEH4 40S ribosomal protein S12 OS=Mus musculus OX=10090 GN=Rps12 PE=1 SV=1 0 27.594 54 5 15 5 137 15.2 8.35 1 3 3 5 1 4 4 6 2216246.938 8434336.469 14555413.84 27095298.25 3 3 3 4 Met-loss+Acetyl [N-Term] metabolic process cytosol;membrane;ribosome RNA binding;structural molecule activity Pf01248 20042 ENSMUSG00000061983.7 Rps12 10 0 High Q9Z2I8 "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial OS=Mus musculus OX=10090 GN=Suclg2 PE=1 SV=3" 0 34.683 32 12 15 12 433 46.8 7.02 1 1 12 1 1 13 3463689.063 4953704.75 11045955.25 79741613 5 2 6 8 metabolic process membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00549, Pf01071, Pf08442, Pf13549" 20917 ENSMUSG00000061838.7 Suclg2 6 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Propanoate metabolism; Carbon metabolism 0 High O70165 Ficolin-1 OS=Mus musculus OX=10090 GN=Fcn1 PE=1 SV=1 0 30.917 34 7 15 7 334 36.3 6.52 7 4 1 1 9 4 1 1 30361535.19 13340297.13 15918613.25 8538006.25 8 4 5 2 defense response;metabolic process;regulation of biological process;response to stimulus extracellular;membrane metal ion binding;protein binding;receptor activity;signal transducer activity "Pf00147, Pf01391, Pf14513" 14133 ENSMUSG00000026938.10 Fcna 2 0 High A0A075B677 Immunoglobulin kappa variable 4-53 OS=Mus musculus OX=10090 GN=Igkv4-53 PE=1 SV=1 0 39.02 64 3 15 3 97 10.4 5.1 2 3 3 1 4 5 5 1 47531618.88 17598419.88 48737778 7091083 4 4 4 1 ENSMUSG00000095753.2 6 0 High Q61554 Fibrillin-1 OS=Mus musculus OX=10090 GN=Fbn1 PE=1 SV=2 0 34.306 7 13 15 12 2873 312.1 4.92 12 1 14 1 10904447.66 30734938 43143504 10 2 1 metabolic process;regulation of biological process;response to stimulus cell surface;extracellular;membrane metal ion binding;protein binding;structural molecule activity "Pf00683, Pf06247, Pf07645, Pf12662, Pf12947, Pf14670" 14118 ENSMUSG00000027204.13 Fbn1 2 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Molecules associated with elastic fibres; Degradation of the extracellular matrix; Post-translational protein phosphorylation; Integrin cell surface interactions 1 High A0A075B5Y1 Immunoglobulin heavy variable V1-74 OS=Mus musculus OX=10090 GN=Ighv1-74 PE=4 SV=1 0 22.774 42 4 15 2 116 12.9 8.88 3 3 2 2 8 3 2 2 17152876.44 2973457 12695190 2697349.25 3 1 2 1 Pf07686 ENSMUSG00000094124.5 12 0 High Q8K310 Matrin-3 OS=Mus musculus OX=10090 GN=Matr3 PE=1 SV=1 0 33.316 9 5 15 5 846 94.6 6.25 3 2 3 2 4 3 6 2 2974164.344 6962345.771 13329093.21 5784351 4 5 5 4 defense response;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus metal ion binding;protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 17184 ENSMUSG00000037236.14 Matr3 18 0 High Q8CGV5 Matrix metallopeptidase 28 (Epilysin) OS=Mus musculus OX=10090 GN=Mmp28 PE=1 SV=1 0 34.809 21 9 15 9 510 57.3 9.47 9 15 8518758 11066026 12758737.25 93252491.25 1 1 2 9 metabolic process;regulation of biological process cytoplasm catalytic activity;metal ion binding "Pf00045, Pf00413, Pf01471, Pf13574, Pf13688" 118453 ENSMUSG00000020682.17 Mmp28 11 0 High A0A075B5P8 Immunoglobulin heavy variable 2-2 (Fragment) OS=Mus musculus OX=10090 GN=Ighv2-2 PE=4 SV=1 0 11.45 19 2 15 1 116 12.6 8.48 2 1 2 2 5 3 4 3 4871417 3353439.5 7434848.5 3299761.75 1 1 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000096464.2 LOC674126 12 0 High A0A140T8N3 Immunoglobulin kappa chain variable 13-84 (Fragment) OS=Mus musculus OX=10090 GN=Igkv13-84 PE=4 SV=2 0 12.871 32 3 15 3 115 12.6 6.51 2 2 3 2 3 3 5 4 20996076.75 14292395.5 40632145 24813627 3 3 3 3 "Pf00047, Pf07686" 692152 ENSMUSG00000076538.1 Igkv13-84 6 0 High Q9D883 Splicing factor U2AF 35 kDa subunit OS=Mus musculus OX=10090 GN=U2af1 PE=1 SV=4 0 24.509 42 7 15 7 239 27.8 8.81 2 3 5 4 2 3 6 4 2851429.594 11708917.75 35238601.5 16628009.75 4 4 6 5 Met-loss+Acetyl [N-Term] metabolic process nucleus;spliceosomal complex metal ion binding;protein binding;RNA binding "Pf00076, Pf00642, Pf13893" 108121 ENSMUSG00000061613.12 U2af1 17 Spliceosome 0 High A0A075B5Q9 Immunoglobulin heavy variable 5-15 OS=Mus musculus OX=10090 GN=Ighv5-15 PE=4 SV=1 0 12.28 33 3 15 1 116 12.9 8.28 3 2 2 1 6 3 5 1 3515314 1 ENSMUSG00000094134.2 12 0 High Q9D8E6 60S ribosomal protein L4 OS=Mus musculus OX=10090 GN=Rpl4 PE=1 SV=3 0 20.852 22 8 15 8 419 47.1 11 1 5 5 4 1 5 5 4 5817802.891 26787884.74 27728347 35874767.06 6 7 7 7 metabolic process;regulation of biological process cytoplasm;endoplasmic reticulum;membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity "Pf00573, Pf14374" 67891 ENSMUSG00000032399.8 Rpl4 9 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High O35129 Prohibitin-2 OS=Mus musculus OX=10090 GN=Phb2 PE=1 SV=1 0 34.157 40 11 15 11 299 33.3 9.83 2 11 2 13 2643287.375 4702579.375 46352861 4 2 6 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;membrane;mitochondrion;nucleus protein binding Pf01145 12034 ENSMUSG00000004264.17 Phb2 6 Processing of SMDT1 0 High H7BX01 "Dynamin-like 120 kDa protein, form S1 OS=Mus musculus OX=10090 GN=Opa1 PE=1 SV=1" 0 38.625 20 13 15 13 978 113.2 7.33 3 2 2 8 3 2 2 8 3961420.281 3424266.25 5241177.25 32907007.5 7 3 4 9 cell death;cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytosol;membrane;mitochondrion catalytic activity;nucleotide binding;protein binding "Pf00350, Pf01926" 74143 ENSMUSG00000038084.16 Opa1 16 0 High P62267 40S ribosomal protein S23 OS=Mus musculus OX=10090 GN=Rps23 PE=1 SV=3 0 15.311 30 5 15 5 143 15.8 10.49 3 4 5 3 4 8 2851467.563 32593132.5 41935966 58935497.5 3 5 5 5 cell organization and biogenesis;metabolic process membrane;ribosome RNA binding;structural molecule activity Pf00164 66475 ENSMUSG00000049517.7 Rps23 13 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High A0A1B0GSX0 L-lactate dehydrogenase OS=Mus musculus OX=10090 GN=Ldha PE=1 SV=1 0 19.916 23 7 14 7 361 39.7 8.35 1 1 2 7 2 1 2 9 7399082.938 3978546.875 8836420.875 41673930.75 6 2 4 6 cell communication;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;nucleotide binding;protein binding "Pf00056, Pf02866" 16828 ENSMUSG00000063229.15 Ldha 7 0 High P01638 Ig kappa chain V-V region L6 (Fragment) OS=Mus musculus OX=10090 PE=4 SV=1 0 16.574 29 2 14 2 115 13 7.81 2 1 2 1 7 3 3 1 37611555.5 16994175.25 26220193.75 7721088.5 3 2 2 1 "Pf00047, Pf07679, Pf07686" 16129; 545847 Igk-V9; Igkv14-111 6 0 High F8VPL5 Mitogen-activated protein kinase kinase kinase kinase 4 OS=Mus musculus OX=10090 GN=Map4k4 PE=1 SV=2 0 25.703 10 10 14 1 1238 141.7 7.44 10 1 13 1 929221.625 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm catalytic activity;nucleotide binding;protein binding;signal transducer activity "Pf00069, Pf00780, Pf07714" 26921 ENSMUSG00000026074.14 Map4k4 1 0 High A0A2I3BQ03 14-3-3 protein zeta/delta (Fragment) OS=Mus musculus OX=10090 GN=Ywhaz PE=1 SV=1 0 6.503 16 3 14 1 166 19.1 5.52 2 3 2 2 3 4 3 4 0 High P97927 Laminin subunit alpha-4 OS=Mus musculus OX=10090 GN=Lama4 PE=1 SV=2 0 34.131 10 12 14 12 1816 201.7 6.21 11 1 13 1 43249152.56 28578923.13 19997733.88 22928190.63 11 3 5 2 cell differentiation;cell organization and biogenesis;regulation of biological process cytoskeleton;extracellular protein binding "Pf00053, Pf00054, Pf02210, Pf03302, Pf04849, Pf05149, Pf05483, Pf06008, Pf06009, Pf06160, Pf10174, Pf12128, Pf13385, Pf13514" 16775 ENSMUSG00000019846.11 Lama4 10 MET activates PTK2 signaling; Laminin interactions African trypanosomiasis; Focal adhesion; Toxoplasmosis; Small cell lung cancer; Pathways in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway; Amoebiasis 0 High P54071 "Isocitrate dehydrogenase [NADP], mitochondrial OS=Mus musculus OX=10090 GN=Idh2 PE=1 SV=3" 0 31.305 24 9 14 9 452 50.9 8.69 5 2 4 8 2 4 10476210.31 16110193.13 6246573.125 23373889 7 6 4 5 metabolic process;regulation of biological process cytosol;membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding Pf00180 269951 ENSMUSG00000030541.16 Idh2 7 Transcriptional activation of mitochondrial biogenesis; Citric acid cycle (TCA cycle) Glutathione metabolism; Citrate cycle (TCA cycle); Metabolic pathways; Biosynthesis of amino acids; 2-Oxocarboxylic acid metabolism; Carbon metabolism; Peroxisome 0 High A0A075B5T2 Immunoglobulin heavy variable 6-3 (Fragment) OS=Mus musculus OX=10090 GN=Ighv6-3 PE=4 SV=7 0 21.562 51 5 14 2 118 13.3 7.84 4 3 3 1 6 4 3 1 14298004 8241712.25 15241633.5 11397844 2 2 2 2 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding "Pf07679, Pf07686" ENSMUSG00000076677.1 12 0 High A0A0A6YW53 Mitogen-activated protein kinase kinase kinase kinase 4 OS=Mus musculus OX=10090 GN=Map4k4 PE=1 SV=1 0 23.224 9 10 14 1 1288 146.6 7.49 10 1 13 1 24822883.44 8980562.5 12159005.88 8738465.5 9 4 4 3 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm catalytic activity;nucleotide binding;protein binding;signal transducer activity "Pf00069, Pf00780, Pf07714" 26921 ENSMUSG00000026074.14 Map4k4 1 8 High P63276 40S ribosomal protein S17 OS=Mus musculus OX=10090 GN=Rps17 PE=1 SV=2 0 32.519 40 5 14 5 135 15.5 9.85 1 3 1 5 1 4 3 6 2303920.313 10669596.5 9141432.875 25989554.5 2 2 2 3 cell organization and biogenesis;metabolic process membrane;ribosome RNA binding;structural molecule activity Pf00833 20068 ENSMUSG00000061787.15 Rps17 7 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High P14869 60S acidic ribosomal protein P0 OS=Mus musculus OX=10090 GN=Rplp0 PE=1 SV=3 0 30.78 28 7 14 7 317 34.2 6.25 3 3 3 4 3 3 4 4 3722368.5 17319850.5 21962170.5 37497824.25 4 4 6 6 response to stimulus;transport cytoplasm;cytosol;endoplasmic reticulum;membrane;nucleus;ribosome RNA binding;structural molecule activity "Pf00428, Pf00466" 11837 ENSMUSG00000067274.10 Rplp0 5 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High P01663 Ig kappa chain V-III region PC 4050 OS=Mus musculus OX=10090 PE=1 SV=1 0 37.084 53 3 14 1 111 12 5.06 3 1 2 5 4 5 67661555.38 103622146 121671747.3 54006549 2 2 2 1 "Pf00047, Pf07679, Pf07686, Pf13927" 0 High Q08857 Platelet glycoprotein 4 OS=Mus musculus OX=10090 GN=Cd36 PE=1 SV=2 0 32.754 20 9 14 9 472 52.7 8.35 2 1 9 2 1 11 5011549.188 9476218 11452463.5 158986851.5 4 5 4 7 cell organization and biogenesis;cellular homeostasis;defense response;metabolic process;regulation of biological process;response to stimulus;transport cell surface;endoplasmic reticulum;Golgi;membrane;mitochondrion protein binding;receptor activity;signal transducer activity Pf01130 12491 ENSMUSG00000002944.15 Cd36 5 Scavenging by Class B Receptors; Cross-presentation of particulate exogenous antigens (phagosomes); Regulation of TLR by endogenous ligand; Neutrophil degranulation; Platelet degranulation PPAR signaling pathway; Fat digestion and absorption; Insulin resistance; Phagosome; Adipocytokine signaling pathway; ECM-receptor interaction; AMPK signaling pathway; Hematopoietic cell lineage; Malaria 0 High P35980 60S ribosomal protein L18 OS=Mus musculus OX=10090 GN=Rpl18 PE=1 SV=3 0 10.281 21 4 14 4 188 21.6 11.78 2 3 3 4 2 4 4 4 2771229.375 19718520 19588785.75 22349788 2 3 3 3 metabolic process cytoplasm;cytosol;endoplasmic reticulum;membrane;nucleus;ribosome RNA binding;structural molecule activity Pf00828 19899 ENSMUSG00000059070.16 Rpl18 7 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High E9PWT4 "H-2 class I histocompatibility antigen, Q7 alpha chain OS=Mus musculus OX=10090 GN=H2-Q7 PE=3 SV=2" 0 40.235 40 10 14 4 310 35.2 6.13 10 14 20402395.25 2 response to stimulus cell surface;endoplasmic reticulum;Golgi;membrane protein binding;RNA binding "Pf00129, Pf07654, Pf08205" 15018 ENSMUSG00000060550.15 H2-Q7 17 1 High P54116 Stomatin OS=Mus musculus OX=10090 GN=Stom PE=1 SV=3 0 31.081 36 8 14 8 284 31.4 6.93 2 1 1 7 2 1 1 10 3868867.609 2168089.766 2177714.797 266109208.1 5 2 2 6 cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton;cytosol;endoplasmic reticulum;membrane;mitochondrion protein binding Pf01145 13830 ENSMUSG00000026880.11 Stom 2 Neutrophil degranulation 0 High Q99N87 "28S ribosomal protein S5, mitochondrial OS=Mus musculus OX=10090 GN=Mrps5 PE=1 SV=1" 0 25.334 23 10 14 10 432 48.2 10.14 3 4 6 3 5 6 1521273.234 21905427.99 22224091.75 40324253 3 7 6 7 metabolic process mitochondrion;ribosome RNA binding;structural molecule activity Pf03719 77721 ENSMUSG00000027374.12 Mrps5 2 Mitochondrial translation termination; Mitochondrial translation elongation Ribosome 0 High Q9QWR8 Alpha-N-acetylgalactosaminidase OS=Mus musculus OX=10090 GN=Naga PE=1 SV=2 0 31.613 25 9 14 4 415 47.2 6.44 2 9 2 12 16652044.33 49740342.53 6 7 metabolic process cytoplasm;vacuole catalytic activity;protein binding Pf02065 17939 ENSMUSG00000022453.7 Naga 15 Glycosphingolipid biosynthesis - globo and isoglobo series; Lysosome 5 High Q9Z204 Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Mus musculus OX=10090 GN=Hnrnpc PE=1 SV=1 0 16.975 19 7 14 7 313 34.4 5.05 3 4 4 2 3 4 5 2 6474590.125 18474491.25 38730197.25 21522589 5 5 7 5 Met-loss+Acetyl [N-Term] cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process cytoskeleton;cytosol;extracellular;membrane;nucleus;spliceosomal complex DNA binding;enzyme regulator activity;protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 15381 ENSMUSG00000060373.14 Hnrnpc 14 mRNA Splicing - Major Pathway; SUMOylation of RNA binding proteins Spliceosome 0 High A0A075B5M7 Immunoglobulin kappa variable 5-39 OS=Mus musculus OX=10090 GN=Igkv5-39 PE=1 SV=7 0 15.418 32 2 14 1 95 10.3 6.25 2 2 2 2 3 2 4 5 10764055 3587107.25 8527667 5783601 1 1 1 1 "Pf00047, Pf07679, Pf07686" ENSMUSG00000076569.3 6 0 High Q8JZR0 Long-chain-fatty-acid--CoA ligase 5 OS=Mus musculus OX=10090 GN=Acsl5 PE=1 SV=1 0 44.467 21 12 14 9 683 76.2 7.09 1 12 1 13 1285268.375 19063585.5 1 4 metabolic process;regulation of biological process;transport endoplasmic reticulum;membrane;mitochondrion;nucleus catalytic activity;nucleotide binding Pf00501 433256 ENSMUSG00000024981.5 Acsl5 19 Synthesis of very long-chain fatty acyl-CoAs PPAR signaling pathway; Fatty acid metabolism; Metabolic pathways; Fatty acid degradation; Adipocytokine signaling pathway; Fatty acid biosynthesis; Peroxisome 0 High A0A075B5R9 Immunoglobulin heavy variable V14-3 (Fragment) OS=Mus musculus OX=10090 GN=Ighv14-3 PE=4 SV=1 0 10.672 26 3 14 1 117 13 8.84 3 1 2 2 7 2 3 2 1897828.25 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding "Pf00047, Pf07686" ENSMUSG00000095642.3 LOC544904 12 0 High F8WJG3 Transformer-2 protein homolog beta OS=Mus musculus OX=10090 GN=Tra2b PE=1 SV=1 0 17.524 29 5 14 5 188 21.9 10.15 3 3 4 3 4 7 4427548.625 26448489.13 53525074.75 22455901.63 4 4 5 3 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus membrane;nucleus;spliceosomal complex protein binding;RNA binding "Pf00076, Pf08777, Pf13893, Pf14259" 20462 ENSMUSG00000022858.15 Tra2b 16 0 High P62754 40S ribosomal protein S6 OS=Mus musculus OX=10090 GN=Rps6 PE=1 SV=1 0 16.08 22 5 14 5 249 28.7 10.84 2 3 4 4 4 6 6297709.75 22430051 36878144.5 50504378.5 2 2 4 4 cell death;cell differentiation;cell proliferation;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity Pf01092 667739; 20104; 105244208 ENSMUSG00000028495.14 Rps6-ps4; Rps6; LOC105244208 2; 4 mTOR signaling pathway; Ribosome; Insulin signaling pathway; Proteoglycans in cancer; HIF-1 signaling pathway; PI3K-Akt signaling pathway; EGFR tyrosine kinase inhibitor resistance 0 High A0A075B5T6 Immunoglobulin heavy variable V10-3 (Fragment) OS=Mus musculus OX=10090 GN=Ighv10-3 PE=4 SV=1 0 8.804 26 3 14 1 119 13.5 8.87 3 2 2 1 6 3 4 1 1025662.813 2771419 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000095700.2 LOC633728 12 0 High A2ADH1 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1 OS=Mus musculus OX=10090 GN=Magt1 PE=1 SV=1 0 17.069 17 8 14 8 368 41.6 10.05 8 14 641023.5 302114614 1 8 metabolic process;transport endoplasmic reticulum;membrane catalytic activity;transporter activity Pf04756 67075 ENSMUSG00000031232.16 Magt1 X Neutrophil degranulation; Miscellaneous transport and binding events 0 High P60867 40S ribosomal protein S20 OS=Mus musculus OX=10090 GN=Rps20 PE=1 SV=1 0 17.633 29 4 14 4 119 13.4 9.94 2 2 3 3 2 2 3 7 7292916.625 24728655.5 28470803.75 49407582 4 4 4 4 metabolic process cytoplasm;membrane;ribosome RNA binding;structural molecule activity Pf00338 67427 ENSMUSG00000028234.6 Rps20 4 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High Q8BK72 "28S ribosomal protein S27, mitochondrial OS=Mus musculus OX=10090 GN=Mrps27 PE=1 SV=2" 0 20.682 19 6 13 6 415 47.7 5.5 4 6 2 5 6 2 689748.0938 15585963.5 16667221.75 15214608.25 3 4 4 3 cell proliferation;regulation of biological process cytoplasm;mitochondrion;ribosome protein binding;RNA binding "Pf10037, Pf13041" 218506 ENSMUSG00000041632.5 Mrps27 13 Mitochondrial translation termination; Mitochondrial translation elongation 0 High Q9CYH2 Peroxiredoxin-like 2A OS=Mus musculus OX=10090 GN=Prxl2a PE=1 SV=2 0 36.722 48 11 13 11 218 24.4 9.17 11 13 1752988.313 124252406 3 10 metabolic process;regulation of biological process cytoplasm;extracellular;mitochondrion antioxidant activity;catalytic activity "Pf00578, Pf13911" 70564 ENSMUSG00000021792.15 5730469M10Rik; Fam213a 14 0 High A0A075B5N9 Immunoglobulin kappa variable 3-7 OS=Mus musculus OX=10090 GN=Igkv3-7 PE=4 SV=7 0 27.511 56 3 13 2 99 10.8 6.25 3 1 2 1 5 2 4 2 20732551.75 5816106 34000949.5 6406424 2 1 2 1 "Pf00047, Pf07679, Pf07686" ENSMUSG00000076598.3 6 0 High Q8VIB3 "Type 2 lactosamine alpha-2,3-sialyltransferase OS=Mus musculus OX=10090 GN=St3gal6 PE=2 SV=3" 0 39.397 28 9 13 9 329 37.8 9.16 9 13 54894102 6 metabolic process;response to stimulus Golgi;membrane catalytic activity Pf00777 54613 ENSMUSG00000022747.16 St3gal6 16 Keratan sulfate biosynthesis; Sialic acid metabolism Metabolic pathways; Glycosphingolipid biosynthesis - lacto and neolacto series 0 High P12787 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Mus musculus OX=10090 GN=Cox5a PE=1 SV=2" 0 18.662 32 4 13 4 146 16.1 6.54 2 3 2 3 2 4 2 5 4841509.75 17058460.75 6459600.75 27315869 3 3 2 3 metabolic process;transport membrane;mitochondrion catalytic activity;metal ion binding;transporter activity Pf02284 12858 ENSMUSG00000000088.7 Cox5a 9 Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 High P54923 [Protein ADP-ribosylarginine] hydrolase OS=Mus musculus OX=10090 GN=Adprh PE=1 SV=1 0 54.336 37 10 13 10 362 40 5.76 10 13 65308257.5 6 metabolic process;regulation of biological process;transport catalytic activity;enzyme regulator activity;metal ion binding;protein binding Pf03747 11544 ENSMUSG00000002844.8 Adprh 16 0 High A0A1L1SQA8 40S ribosomal protein S25 OS=Mus musculus OX=10090 GN=Rps25 PE=1 SV=1 0 7.951 28 3 13 3 93 10.3 9.99 1 3 3 2 1 4 4 4 6585141.75 27500725 29140804.5 54004347 3 3 3 3 Pf03297 ENSMUSG00000009927.9 9 0 High D3Z7R9 Cell cycle progression protein 1 OS=Mus musculus OX=10090 GN=Ccpg1 PE=1 SV=1 0 38.146 16 11 13 11 778 89.1 6.06 11 13 37434733.5 5 regulation of biological process membrane protein binding 72278 ENSMUSG00000034563.16 Ccpg1 9 0 High D3Z0M9 RNA helicase OS=Mus musculus OX=10090 GN=Ddx23 PE=1 SV=1 0 32.352 16 10 13 10 819 95.4 9.58 1 10 1 1 11 1 351051.4063 16869047.5 29966129.75 14678828.38 2 6 6 5 metabolic process cytoplasm;nucleus;spliceosomal complex catalytic activity;DNA binding;nucleotide binding;RNA binding "Pf00270, Pf00271, Pf04851" 74351 ENSMUSG00000003360.14 Ddx23 15 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway Spliceosome 0 High A0A075B5V8 Immunoglobulin heavy variable 1-47 OS=Mus musculus OX=10090 GN=Ighv1-47 PE=4 SV=1 0 18.862 38 3 13 2 98 11.1 8.4 1 2 2 5 3 5 2493037 11455686 11569729 1 2 2 Pf07686 ENSMUSG00000076709.2 LOC634759 12 0 High P54818 Galactocerebrosidase OS=Mus musculus OX=10090 GN=Galc PE=1 SV=2 0 25.135 14 6 13 6 684 77.2 6.74 2 1 4 4 2 1 4 6 5851551.875 5542580.359 18711090.25 36441404.5 3 5 5 5 metabolic process mitochondrion;vacuole catalytic activity Pf02057 14420 ENSMUSG00000021003.9 Galc 12 Glycosphingolipid metabolism Metabolic pathways; Lysosome; Sphingolipid metabolism 0 High Q9D9N8 Protease-associated domain-containing protein 1 OS=Mus musculus OX=10090 GN=Pradc1 PE=1 SV=1 0 19.53 45 7 13 7 188 21.1 5.72 1 7 1 12 282702.1563 1299045.5 15136524.63 111023713 1 1 5 5 extracellular Pf02225 73327 ENSMUSG00000030008.9 Pradc1 6 0 High Q80SW1 S-adenosylhomocysteine hydrolase-like protein 1 OS=Mus musculus OX=10090 GN=Ahcyl1 PE=1 SV=1 0 28.965 19 8 13 8 530 58.9 6.89 8 1 12 1 14444717.56 3994201.5 4405939.875 12596063.63 8 2 2 4 Met-loss+Acetyl [N-Term] metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;endoplasmic reticulum;membrane catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00670, Pf01262, Pf01488, Pf02254, Pf02826, Pf05221" 229709 ENSMUSG00000027893.14 Ahcyl1 3 Ion homeostasis Metabolic pathways; Cysteine and methionine metabolism 0 High Q9CR57 60S ribosomal protein L14 OS=Mus musculus OX=10090 GN=Rpl14 PE=1 SV=3 0 16.187 21 4 13 4 217 23.5 11.02 1 3 2 3 2 4 3 4 10044856 33005111.5 26574281.25 32378519 4 4 4 3 metabolic process membrane;ribosome protein binding;RNA binding;structural molecule activity Pf01929 67115 ENSMUSG00000025794.9 Rpl14 9 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q8BP67 60S ribosomal protein L24 OS=Mus musculus OX=10090 GN=Rpl24 PE=1 SV=2 0 15.276 35 6 13 6 157 17.8 11.25 1 3 3 4 1 4 3 5 5351392.031 15851935.25 17927274.25 26150319 4 4 4 4 cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process cytoplasm;membrane;ribosome protein binding;RNA binding;structural molecule activity Pf01246 68193 ENSMUSG00000098274.7 Rpl24 16 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q8R404 MICOS complex subunit MIC13 OS=Mus musculus OX=10090 GN=Micos13 PE=1 SV=1 0 31.432 56 4 12 4 119 13.4 8.63 1 1 1 4 1 2 1 8 1718532.375 4971767.313 5320874.875 75323195.5 3 3 3 4 cell organization and biogenesis membrane;mitochondrion 224904 ENSMUSG00000049760.5 2410015M20Rik 17 0 High E9Q0B5 Fc fragment of IgG-binding protein OS=Mus musculus OX=10090 GN=Fcgbp PE=1 SV=1 0.003 3.23 0 1 12 1 2583 275 5.03 1 1 1 1 3 3 2 4 68968517.47 41694972 55370952 274087072 2 1 1 1 protein binding "Pf00094, Pf01826, Pf08742, Pf12714" ENSMUSG00000047730.17 7 0 High P14115 60S ribosomal protein L27a OS=Mus musculus OX=10090 GN=Rpl27a PE=1 SV=5 0 15.799 24 4 12 4 148 16.6 11.12 2 2 2 4 3 2 2 5 4017620 15275058 15582150.25 27403950 3 3 3 4 metabolic process cytosol;endoplasmic reticulum;membrane;ribosome RNA binding;structural molecule activity Pf00828 26451 ENSMUSG00000046364.14 Rpl27a 7 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 Medium Q3TCN2 Putative phospholipase B-like 2 OS=Mus musculus OX=10090 GN=Plbd2 PE=1 SV=2 0.016 1.432 1 1 12 1 594 66.2 6.13 1 1 1 1 5 2 3 2 6697748 9086541 11662126 13975817 1 1 1 1 metabolic process organelle lumen;vacuole catalytic activity Pf04916 71772 ENSMUSG00000029598.12 Plbd2 5 0 High Q542V3 Serine/arginine-rich-splicing factor 4 OS=Mus musculus OX=10090 GN=Srsf4 PE=1 SV=1 0 6.227 5 3 12 1 491 56.2 11.37 1 2 3 2 2 3 4 3 461821.6875 2711006.5 6192454.5 3252925 1 1 1 1 cell differentiation;metabolic process;regulation of biological process;response to stimulus nucleus RNA binding "Pf00076, Pf13893, Pf14259" 57317 ENSMUSG00000028911.16 Srsf4 4 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript Herpes simplex infection; Spliceosome 0 High B1ARA5 60S ribosomal protein L26 OS=Mus musculus OX=10090 GN=Rpl26 PE=1 SV=1 0 5.301 17 3 12 3 143 17 10.55 3 2 2 2 4 3 2 3 3947156.438 9765468 13592640.75 21430711.5 3 2 3 3 metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;ribosome protein binding;RNA binding;structural molecule activity 19941 ENSMUSG00000060938.14 Rpl26 11 0 High Q3UVK0 Endoplasmic reticulum metallopeptidase 1 OS=Mus musculus OX=10090 GN=Ermp1 PE=1 SV=2 0 54.277 13 8 12 8 898 100.1 7.49 8 12 545703.9063 1374790.625 63280236 2 1 5 metabolic process endoplasmic reticulum;membrane catalytic activity;metal ion binding "Pf04389, Pf14264" 226090 ENSMUSG00000046324.12 Ermp1 19 0 High Q99LT0 Protein dpy-30 homolog OS=Mus musculus OX=10090 GN=Dpy30 PE=1 SV=1 0 13.538 45 3 12 3 99 11.2 4.88 3 1 3 1 5 2 4 1 4349454.641 1570454.156 5046715 3623894.125 3 2 3 2 cell organization and biogenesis;metabolic process;regulation of biological process;transport Golgi;nucleus catalytic activity;protein binding Pf05186 66310 ENSMUSG00000024067.13 Dpy30 17 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; PKMTs methylate histone lysines 0 High D3Z1Y1 RING-type E3 ubiquitin transferase OS=Mus musculus OX=10090 GN=Syvn1 PE=1 SV=1 0 12.966 14 7 12 7 608 66.9 7.08 2 7 3 9 382183.5313 24833471.13 62229482.22 8132993.5 1 6 7 3 metabolic process membrane catalytic activity;metal ion binding;protein binding "Pf00097, Pf12678, Pf12861, Pf12906, Pf13445, Pf13639, Pf13920, Pf13923, Pf14634" ENSMUSG00000024807.17 19 Hedgehog ligand biogenesis; ER Quality Control Compartment (ERQC) 0 High V9GX38 Predicted gene 17190 OS=Mus musculus OX=10090 GN=Gm17190 PE=1 SV=1 0 15.811 8 3 12 2 357 37.7 8.85 1 3 2 2 1 6 3 2 RNA binding "Pf00076, Pf13893, Pf14259" ENSMUSG00000099115.1 LOC625454 13 0 High D3Z1S8 40S ribosomal protein S5 (Fragment) OS=Mus musculus OX=10090 GN=Rps5 PE=1 SV=1 0 18.446 27 5 12 5 189 21.1 9.52 2 2 3 4 2 3 3 4 3801438.688 23305406.25 28330855.5 51699446.5 2 5 5 5 metabolic process ribosome RNA binding;structural molecule activity Pf00177 ENSMUSG00000012848.15 7 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" 0 High Q99LF4 RNA-splicing ligase RtcB homolog OS=Mus musculus OX=10090 GN=Rtcb PE=1 SV=1 0 18.002 17 8 12 8 505 55.2 7.23 6 2 1 2 6 2 2 2 5559258.75 5590531.727 11871058 24162839.13 7 4 5 8 metabolic process cytoplasm;cytosol;membrane;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding;RNA binding Pf01139 28088 ENSMUSG00000001783.3 D10Wsu52e; Rtcb 10 0 High P26443 "Glutamate dehydrogenase 1, mitochondrial OS=Mus musculus OX=10090 GN=Glud1 PE=1 SV=1" 0 16.834 15 8 12 8 558 61.3 8 5 1 1 4 5 1 1 5 10674980.57 10656603.19 7877542.297 40196585.38 6 4 3 5 metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding;protein binding "Pf00208, Pf02812" 14661 ENSMUSG00000021794.15 Glud1 14 Transcriptional activation of mitochondrial biogenesis; Amino acid synthesis and interconversion (transamination) "Metabolic pathways; Nitrogen metabolism; Proximal tubule bicarbonate reclamation; Carbon metabolism; D-Glutamine and D-glutamate metabolism; Alanine, aspartate and glutamate metabolism; Arginine biosynthesis" 0 High Q9JK42 "[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial OS=Mus musculus OX=10090 GN=Pdk2 PE=1 SV=2" 0 17.941 15 6 12 6 407 46 6.61 3 1 1 6 4 1 1 6 3958117.813 2407395.75 8444683.25 25675330.5 4 2 4 5 cell communication;metabolic process;regulation of biological process;response to stimulus cytosol;mitochondrion;organelle lumen catalytic activity;nucleotide binding;protein binding "Pf02518, Pf10436" 18604 ENSMUSG00000038967.13 Pdk2 11 Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid 0 High P10922 Histone H1.0 OS=Mus musculus OX=10090 GN=H1-0 PE=2 SV=4 0 11.444 21 4 12 4 194 20.8 10.9 2 2 2 4 3 3 2 4 16162754.75 19618650.25 24725731 32340618.5 4 4 4 4 cell organization and biogenesis chromosome;cytoskeleton;Golgi;nucleus DNA binding;RNA binding Pf00538 14958 ENSMUSG00000096210.1 H1f0 15 Activation of DNA fragmentation factor; Formation of Senescence-Associated Heterochromatin Foci (SAHF) 0 High P50427 Steryl-sulfatase OS=Mus musculus OX=10090 GN=Sts PE=1 SV=1 0 42.853 16 8 12 8 624 66.5 8.5 8 12 26579781.13 4 metabolic process endoplasmic reticulum;membrane catalytic activity;metal ion binding "Pf00884, Pf01663, Pf14707" 20905 Sts X|Y Steroid hormone biosynthesis 0 High F7CUP3 Amidohydrolase domain-containing protein 2 OS=Mus musculus OX=10090 GN=Amdhd2 PE=1 SV=2 0 18.883 17 5 12 5 446 47.1 6.87 2 4 3 2 6 4 262449.0625 11012561.25 18931148 17758032.25 1 3 3 3 0 High Q791V5 Mitochondrial carrier homolog 2 OS=Mus musculus OX=10090 GN=Mtch2 PE=1 SV=1 0 48.483 27 6 12 6 303 33.5 8.25 1 6 1 11 2931524.75 5206718 5743886.875 81857867.25 4 3 3 7 Met-loss+Acetyl [N-Term] cell death;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport membrane;mitochondrion;nucleus Pf00153 56428 ENSMUSG00000027282.17; ENSMUSG00000111714.1 Mtch2 2; CHR_MG191_PATCH 0 High A0A075B5S6 Immunoglobulin heavy variable 3-1 (Fragment) OS=Mus musculus OX=10090 GN=Ighv3-1 PE=4 SV=1 0 9.795 19 2 12 1 116 13.1 8.02 2 1 2 1 6 1 4 1 4996127 2688116 7101268.5 1 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000093838.1 LOC674136 12 Regulation of Complement cascade; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Cell surface interactions at the vascular wall; FCERI mediated NF-kB activation; Role of LAT2/NTAL/LAB on calcium mobilization; Role of phospholipids in phagocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR activation; Classical antibody-mediated complement activation; FCERI mediated Ca+2 mobilization; FCERI mediated MAPK activation; CD22 mediated BCR regulation; Scavenging of heme from plasma 0 High P08607 C4b-binding protein OS=Mus musculus OX=10090 GN=C4bpa PE=1 SV=3 0 29.048 19 7 12 7 469 51.5 7.15 7 2 10 2 16544804.63 2702459 11547812.25 1977841.25 7 1 4 1 defense response;metabolic process;regulation of biological process;response to stimulus extracellular protein binding;RNA binding Pf00084 12269 ENSMUSG00000026405.14 C4bp 1 Complement and coagulation cascades; Pertussis 0 High Q6ZWZ4 60S ribosomal protein L36 OS=Mus musculus OX=10090 GN=Rpl36 PE=1 SV=1 0 8.422 30 3 12 3 105 12.2 11.59 2 2 3 2 2 3 3 4 4857981.375 19495713 15966379.75 28804025 3 3 3 3 metabolic process ribosome RNA binding;structural molecule activity Pf01158 54217 ENSMUSG00000057863.5 Rpl36 17 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High A0A075B5T3 Immunoglobulin heavy variable 6-6 (Fragment) OS=Mus musculus OX=10090 GN=Ighv6-6 PE=4 SV=1 0 15.844 39 4 12 1 119 13.3 7.08 3 1 2 2 6 2 2 2 18420821 9370563.75 15928839.5 10141804.75 2 2 2 2 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000076680.1 LOC677040 12 1 High Q9CPX7 "28S ribosomal protein S16, mitochondrial OS=Mus musculus OX=10090 GN=Mrps16 PE=1 SV=1" 0 20.395 40 4 12 4 135 15.2 9.67 1 3 2 3 1 4 3 4 668585.3125 12233041.5 13863075.25 13753952.5 1 2 3 2 cell organization and biogenesis;metabolic process cytosol;mitochondrion;ribosome structural molecule activity Pf00886 66242 ENSMUSG00000049960.3 Mrps16 14 Mitochondrial translation termination; Mitochondrial translation elongation Ribosome 0 High Q9CXE7 Transmembrane emp24 domain-containing protein 5 OS=Mus musculus OX=10090 GN=Tmed5 PE=1 SV=1 0 24.213 22 6 12 6 229 26.2 4.93 6 12 141313056.5 5 cell organization and biogenesis;transport endoplasmic reticulum;Golgi;membrane Pf01105 73130 ENSMUSG00000063406.11 Tmed5 5 WNT ligand biogenesis and trafficking 0 High A2APT9 Kelch domain-containing protein 7A OS=Mus musculus OX=10090 GN=Klhdc7a PE=1 SV=3 0 39.014 15 9 12 9 773 83.5 6.33 1 9 1 11 174431.3359 404799.2734 581239.625 34249426.38 1 1 1 5 metabolic process membrane catalytic activity;protein binding "Pf01344, Pf13964" 242721 ENSMUSG00000078234.6 Klhdc7a 4 0 High P01724 Ig lambda-1 chain V regions MOPC 104E/RPC20/J558/S104 OS=Mus musculus OX=10090 PE=1 SV=1 0 7.942 33 2 12 2 129 13.5 7.28 2 1 1 1 6 3 2 1 111812010.8 82971528 133155664 16660925 2 1 1 1 response to stimulus Pf07686 16142 Iglv1 16 0 High P18242 Cathepsin D OS=Mus musculus OX=10090 GN=Ctsd PE=1 SV=1 0 26.724 23 7 12 7 410 44.9 7.15 7 12 174289.375 3384081.438 133039862.5 1 2 7 cell organization and biogenesis;metabolic process extracellular;membrane;mitochondrion;vacuole catalytic activity "Pf00026, Pf07966, Pf14541, Pf14543" 13033 ENSMUSG00000007891.16 Ctsd 7 MHC class II antigen presentation; Neutrophil degranulation; Collagen degradation Tuberculosis; Lysosome; Sphingolipid signaling pathway; Apoptosis 0 High Q80YR5 Scaffold attachment factor B2 OS=Mus musculus OX=10090 GN=Safb2 PE=1 SV=2 0 35.246 10 7 12 2 991 111.8 6.38 6 3 9 3 2987576.625 1712612.25 2 1 cell differentiation;metabolic process;regulation of biological process cytoplasm;nucleus DNA binding;protein binding;RNA binding "Pf00076, Pf02037, Pf13893, Pf14259" 224902 ENSMUSG00000042625.16 Safb2 17 0 High P62315 Small nuclear ribonucleoprotein Sm D1 OS=Mus musculus OX=10090 GN=Snrpd1 PE=1 SV=1 0 20.869 45 3 11 3 119 13.3 11.56 2 2 2 2 2 3 3 3 1582887.25 6279928.563 13835408.13 14213252.63 2 2 2 2 cell organization and biogenesis;metabolic process cytoplasm;cytosol;nucleus;spliceosomal complex RNA binding Pf01423 20641 ENSMUSG00000002477.4 Snrpd1 18 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; snRNP Assembly Spliceosome; Systemic lupus erythematosus 0 High P60843 Eukaryotic initiation factor 4A-I OS=Mus musculus OX=10090 GN=Eif4a1 PE=1 SV=1 0 19.23 14 4 11 1 406 46.1 5.48 4 1 1 1 6 1 3 1 metabolic process;regulation of biological process cytoplasm;membrane catalytic activity;DNA binding;nucleotide binding;protein binding;RNA binding "Pf00270, Pf00271, Pf04851" 13681 ENSMUSG00000059796.16 Eif4a1 11 L13a-mediated translational silencing of Ceruloplasmin expression; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ISG15 antiviral mechanism; Translation initiation complex formation; Deadenylation of mRNA RNA transport 0 High P79568 Class Ib MHC antigen Qa-2 OS=Mus musculus OX=10090 GN=H2-Q6 PE=1 SV=1 0 22.9 25 8 11 2 326 37.4 6.24 8 11 2520806.25 10406399 1 1 cell surface;endoplasmic reticulum;Golgi;membrane protein binding;RNA binding "Pf00129, Pf07654, Pf08205" 110557 ENSMUSG00000073409.12 H2-Q6 17 Endocytosis; Herpes simplex infection; Allograft rejection; Epstein-Barr virus infection; Cell adhesion molecules (CAMs); HTLV-I infection; Phagosome; Graft-versus-host disease; Viral myocarditis; Antigen processing and presentation; Type I diabetes mellitus; Autoimmune thyroid disease; Viral carcinogenesis 0 High P01660 Ig kappa chain V-III region PC 3741/TEPC 111 OS=Mus musculus OX=10090 PE=1 SV=1 0 25.475 49 3 11 1 111 12.1 5.38 3 1 2 1 5 1 3 2 15155349 11436989 49356192 8298355.5 1 1 1 1 "Pf00047, Pf07679, Pf07686" LOC676215 0 High A0A0A6YXN4 Immunoglobulin heavy variable V1-18 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-18 PE=1 SV=1 0 15.738 41 4 11 2 117 12.9 7.94 2 2 2 2 2 3 3 3 16435136.5 10778341 22483489 9098107 2 1 2 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000076695.7 12 0 High P01636 Ig kappa chain V-V region MOPC 149 OS=Mus musculus OX=10090 PE=1 SV=1 0 11.56 35 3 11 1 108 12 7.28 3 2 1 1 4 3 3 1 1765712.125 1 metabolic process Pf00330 545851 Igkv12-44 6 0 High D3Z3N4 Heterogeneous nuclear ribonucleoprotein H3 OS=Mus musculus OX=10090 GN=Hnrnph3 PE=1 SV=1 0 13.132 16 5 11 4 346 36.8 6.87 4 4 1 5 5 1 11697352.5 11774459.25 1693482.875 3 3 1 cell differentiation nucleus RNA binding "Pf00076, Pf14259" 432467 ENSMUSG00000020069.16 Hnrnph3 10 0 High A2AJR5 Receptor protein serine/threonine kinase OS=Mus musculus OX=10090 GN=Acvr1c PE=3 SV=1 0 31.04 20 7 11 7 413 46.1 7.46 7 11 532517.9844 75611010.5 2 7 cell death;cell differentiation;cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;membrane catalytic activity;metal ion binding;nucleotide binding;protein binding;receptor activity;signal transducer activity "Pf00069, Pf01064, Pf07714, Pf08515" 269275 ENSMUSG00000026834.13 Acvr1c 2 0 High O88441 Metaxin-2 OS=Mus musculus OX=10090 GN=Mtx2 PE=1 SV=1 0 26.801 49 7 11 7 263 29.7 5.63 4 1 4 5 1 5 5152992.969 169534.6094 4089344.578 20113005.75 4 1 3 5 Met-loss+Acetyl [N-Term] transport membrane;mitochondrion "Pf11801, Pf13410, Pf14497" 53375 ENSMUSG00000027099.9 Mtx2 2 0 High Q8BTU6 RNA helicase OS=Mus musculus OX=10090 GN=Eif4a2 PE=1 SV=1 0 18.259 13 4 11 1 362 41.3 5.64 4 1 1 1 6 1 3 1 2554191.094 1368363 3281286.375 3 1 2 metabolic process;regulation of biological process cytoplasm catalytic activity;DNA binding;nucleotide binding;RNA binding "Pf00270, Pf00271, Pf04851" 13682 ENSMUSG00000022884.14 Eif4a2 16 2 High A0A075B5P9 Immunoglobulin heavy variable 5-4 (Fragment) OS=Mus musculus OX=10090 GN=Ighv5-4 PE=4 SV=1 0 8.292 19 2 11 1 117 13 8.6 2 2 2 3 4 4 3392884.75 6491590.25 5649097.25 2312650 1 1 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000095612.2 LOC674129 12 0 High Q7TNC4 Putative RNA-binding protein Luc7-like 2 OS=Mus musculus OX=10090 GN=Luc7l2 PE=1 SV=1 0 23.958 20 7 11 7 392 46.6 10.1 1 5 4 1 6 4 720527.75 10570736.63 29291385.75 12930836.38 1 5 5 4 cell organization and biogenesis nucleus;spliceosomal complex protein binding;RNA binding Pf03194 192196 ENSMUSG00000029823.16 Luc7l2 6 0 High Q9D8L3 Signal sequence receptor subunit delta OS=Mus musculus OX=10090 GN=Ssr4 PE=1 SV=1 0 30.939 37 6 11 6 173 19 5.78 6 11 873842.7344 208439206 2 5 endoplasmic reticulum;membrane Pf05404 20832 ENSMUSG00000002014.12 Ssr4 X 0 High A0A0B4J1H6 Immunoglobulin kappa chain variable 2-137 (Fragment) OS=Mus musculus OX=10090 GN=Igkv2-137 PE=4 SV=1 0 7.502 20 2 11 2 120 13.1 7.24 2 2 1 2 3 4 2 2 30895247 24029128 35530349.5 16781657.5 2 2 2 2 response to stimulus "Pf00047, Pf07686" 692187 ENSMUSG00000076501.2 Igkv2-137 6 0 High P62317 Small nuclear ribonucleoprotein Sm D2 OS=Mus musculus OX=10090 GN=Snrpd2 PE=1 SV=1 0 14.224 47 6 11 6 118 13.5 9.91 1 1 6 2 1 2 6 2 2963447.688 29659107 71768533.25 32466533.5 3 5 6 6 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process cytoplasm;cytosol;nucleus;spliceosomal complex RNA binding Pf01423 107686 ENSMUSG00000040824.3 Snrpd2 7 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; snRNP Assembly Spliceosome 0 High Q9WUA5 Laforin OS=Mus musculus OX=10090 GN=Epm2a PE=1 SV=2 0 25.774 29 7 11 7 330 36.9 6.32 7 1 10 1 38846785.25 4469498.375 2390134.75 11528816.5 6 2 1 3 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;endoplasmic reticulum;membrane;nucleus catalytic activity;protein binding;receptor activity;signal transducer activity "Pf00686, Pf00782, Pf05222" 13853 ENSMUSG00000055493.4 Epm2a 10 Glycogen synthesis 0 High P83093 Stromal interaction molecule 2 OS=Mus musculus OX=10090 GN=Stim2 PE=1 SV=2 0 37.246 20 11 11 11 746 83.9 6.79 11 11 295125.0625 25272382.5 1 4 cellular homeostasis;regulation of biological process;transport endoplasmic reticulum;membrane metal ion binding;protein binding;transporter activity "Pf00536, Pf07647, Pf13868" 116873 ENSMUSG00000039156.19 Stim2 5 Calcium signaling pathway 0 High A0A075B5K7 Immunoglobulin kappa chain variable 14-100 OS=Mus musculus OX=10090 GN=Igkv14-100 PE=4 SV=7 0 8.546 14 1 11 1 116 12.6 4.78 1 1 1 1 4 3 3 1 15195795.75 6620657 14998073.5 11085786.75 1 1 1 1 "Pf00047, Pf07679, Pf07686" ENSMUSG00000096515.5 6 0 High Q9CXW4 60S ribosomal protein L11 OS=Mus musculus OX=10090 GN=Rpl11 PE=1 SV=4 0 11.476 20 3 11 3 178 20.2 9.6 1 1 2 3 2 2 3 4 5148169.125 17707520.25 16935855 29046385.5 2 3 3 3 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity "Pf00281, Pf00673" 67025 ENSMUSG00000059291.15 Rpl11 4 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q9D1R9 60S ribosomal protein L34 OS=Mus musculus OX=10090 GN=Rpl34 PE=1 SV=2 0 7.35 28 4 11 4 117 13.3 11.47 1 3 4 1 1 4 5 1 3462264.75 16580612.5 19061607.75 15508527.5 2 3 3 2 metabolic process mitochondrion;ribosome protein binding;RNA binding;structural molecule activity Pf01199 619547; 68436; 100043876 ENSMUSG00000062006.12 Rpl34-ps1; Rpl34; Gm4705 6; 3; 17 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High A0A0B4J1I3 Immunoglobulin kappa variable 4-74 (Fragment) OS=Mus musculus OX=10090 GN=Igkv4-74 PE=4 SV=1 0 22.854 64 3 11 2 119 12.9 8.02 3 2 1 6 2 3 5420344.375 2386553.25 6163029.25 2 1 2 response to stimulus Pf07686 236047 ENSMUSG00000076543.2 Igkv4-74 6 0 High E9Q317 18 kDa Sin3-associated polypeptide OS=Mus musculus OX=10090 GN=Sap18 PE=1 SV=1 0 13.993 28 6 11 6 172 19.6 9.8 3 6 3 8 187932.6094 15088424 23196397.5 6067664 1 3 3 2 regulation of biological process cytosol protein binding;RNA binding Pf06487 20220; 100041953 ENSMUSG00000021963.16; ENSMUSG00000061104.5 Sap18; Gm10094; Sap18b 14; 8 mRNA surveillance pathway; RNA transport 0 High P24270 Catalase OS=Mus musculus OX=10090 GN=Cat PE=1 SV=4 0 29.023 19 9 11 9 527 59.8 7.88 9 11 8690142.625 1876919.25 3867097.875 8 1 2 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytosol;endoplasmic reticulum;Golgi;membrane;mitochondrion;vacuole antioxidant activity;catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00199, Pf06628" 12359 ENSMUSG00000027187.10 Cat 2 Neutrophil degranulation; Detoxification of Reactive Oxygen Species FoxO signaling pathway; Tryptophan metabolism; Amyotrophic lateral sclerosis (ALS); Longevity regulating pathway; Carbon metabolism; Glyoxylate and dicarboxylate metabolism; Longevity regulating pathway - multiple species; Peroxisome 0 High A0A0A6YVW3 Immunoglobulin heavy variable V1-23 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-23 PE=4 SV=1 0 18.696 28 4 11 1 117 12.9 6.51 4 1 1 1 6 3 1 1 8953703.938 11611316.38 4945471.5 3441064.75 1 1 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000103290.1 12 0 High Q6P6J9 Thioredoxin domain-containing protein 15 OS=Mus musculus OX=10090 GN=Txndc15 PE=1 SV=1 0 37.372 31 6 11 6 344 38.1 4.77 6 11 97505135.5 4 cellular homeostasis;regulation of biological process membrane Pf00085 69672 ENSMUSG00000021497.9 Txndc15 13 0 High P55096 ATP-binding cassette sub-family D member 3 OS=Mus musculus OX=10090 GN=Abcd3 PE=1 SV=2 0 40.92 23 11 11 11 659 75.4 9.26 11 11 481094.0469 55258480.5 2 10 cell organization and biogenesis;metabolic process;response to stimulus;transport membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding;protein binding;transporter activity "Pf00005, Pf06472" 19299 ENSMUSG00000028127.10 Abcd3 3 ABC transporters in lipid homeostasis ABC transporters; Peroxisome 0 Medium Q6AXE3 Abca3 protein OS=Mus musculus OX=10090 GN=Abca3 PE=1 SV=1 0.017 1.363 1 1 11 1 1449 163.4 7.83 1 1 1 1 4 2 3 2 29956644 28862521 36075157.5 43872428 1 1 1 1 transport membrane catalytic activity;nucleotide binding;transporter activity "Pf00005, Pf03193, Pf12698, Pf13304, Pf13476" 27410 ENSMUSG00000024130.15 Abca3 17 ABC transporters 0 High P34914 Bifunctional epoxide hydrolase 2 OS=Mus musculus OX=10090 GN=Ephx2 PE=1 SV=2 0 21.693 25 9 10 9 554 62.5 6.19 8 1 1 8 1 1 8149251.516 1747754.313 1737402.625 9185467.25 8 2 1 2 defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol catalytic activity;metal ion binding;protein binding "Pf00561, Pf00702, Pf12146, Pf12695, Pf12697, Pf13242, Pf13419" 13850 ENSMUSG00000022040.7 Ephx2 14 Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) Metabolic pathways; Arachidonic acid metabolism; Peroxisome 0 High J3QK03 Immunoglobulin heavy variable V6-5 OS=Mus musculus OX=10090 GN=Ighv6-5 PE=4 SV=1 0 17.672 39 3 10 0 99 11.1 5.12 3 1 2 7 1 2 ENSMUSG00000096407.2 12 0 High A0A2R8VHY9 Poly(rC)-binding protein 2 (Fragment) OS=Mus musculus OX=10090 GN=Pcbp2 PE=1 SV=1 0 15.216 22 4 10 2 249 26.4 7.77 3 2 3 5 2 3 6907870.375 1319882.75 6577035.75 5038636 3 1 2 1 2 High A0A075B684 Immunoglobulin heavy variable 1-62-1 OS=Mus musculus OX=10090 GN=Ighv1-62-1 PE=4 SV=1 0 11.137 63 1 10 1 30 3.2 9.04 1 1 1 1 3 3 3 1 20321950.25 17663032.25 16602100.13 21285789 1 1 1 1 ENSMUSG00000102313.1 12 0 High Q9DAM5 Mitochondrial thiamine pyrophosphate carrier OS=Mus musculus OX=10090 GN=Slc25a19 PE=1 SV=1 0 28.283 28 9 10 9 318 35.6 9.2 9 10 174543.7969 46793683.5 1 6 transport membrane;mitochondrion;nucleus transporter activity Pf00153 67283 ENSMUSG00000020744.13 Slc25a19 11 Vitamin B1 (thiamin) metabolism 0 High Q9CPR4 60S ribosomal protein L17 OS=Mus musculus OX=10090 GN=Rpl17 PE=1 SV=3 0 16.908 29 4 10 4 184 21.4 10.18 2 2 1 4 2 2 1 5 1403553.75 15028113.25 17603999.5 22280339.5 1 3 3 3 metabolic process;regulation of biological process nucleus;ribosome protein binding;RNA binding;structural molecule activity Pf00237 319195 Rpl17 18 0 High O35326 Serine/arginine-rich splicing factor 5 OS=Mus musculus OX=10090 GN=Srsf5 PE=1 SV=2 0 7.184 12 3 10 2 269 30.9 11.56 1 2 2 1 2 3 3 2 206792.7813 2890275.5 1 1 metabolic process;regulation of biological process;response to stimulus nucleus protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 20384 ENSMUSG00000021134.17 Srsf5 12 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript Herpes simplex infection; Spliceosome 0 High A0A075B5S9 Immunoglobulin heavy variable 9-4 OS=Mus musculus OX=10090 GN=Ighv9-4 PE=4 SV=1 0 6.225 35 3 10 2 98 10.9 9.07 2 3 2 1 3 3 3 1 11589717.25 7266409.375 20389457.63 10008191.5 2 2 3 2 "Pf00047, Pf07686" ENSMUSG00000094322.2 12 1 High Q3TRM4 Patatin-like phospholipase domain-containing protein 6 OS=Mus musculus OX=10090 GN=Pnpla6 PE=1 SV=2 0 34.268 9 7 10 7 1355 149.4 7.83 2 5 3 2 5 3 5569370.625 17463643.5 11009350 3 4 3 metabolic process endoplasmic reticulum;membrane catalytic activity "Pf00027, Pf01734" 50767 Pnpla6 8 Glycerophospholipid catabolism Glycerophospholipid metabolism 0 High A0A0B4J1M0 Immunoglobulin heavy variable 1-77 OS=Mus musculus OX=10090 GN=Ighv1-77 PE=1 SV=1 0 9.332 41 3 10 2 98 10.7 9.22 3 1 1 1 6 1 2 1 13509794.63 1175207.625 2 1 "Pf00047, Pf07686" 16061 ENSMUSG00000096452.2 Igh-VJ558 12 0 High Q80X85 "28S ribosomal protein S7, mitochondrial OS=Mus musculus OX=10090 GN=Mrps7 PE=1 SV=1" 0 24.077 32 8 10 8 242 28 9.94 4 3 3 4 3 3 8491521.5 13017599 14806264.5 3 3 3 cell organization and biogenesis;metabolic process mitochondrion;ribosome RNA binding;structural molecule activity Pf00177 50529 ENSMUSG00000046756.10 Mrps7 11 Mitochondrial translation termination; Mitochondrial translation elongation Ribosome 0 High Q91VR5 ATP-dependent RNA helicase DDX1 OS=Mus musculus OX=10090 GN=Ddx1 PE=1 SV=1 0 19.187 11 6 10 6 740 82.4 7.21 2 3 2 2 3 3 2 2 3073917.219 4919141.313 8754009.5 3481124.75 4 3 4 2 development;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;nucleus catalytic activity;DNA binding;nucleotide binding;protein binding;RNA binding "Pf00270, Pf00271, Pf00622" 104721 ENSMUSG00000037149.9 Ddx1 12 0 High Q9WUA2 Phenylalanine--tRNA ligase beta subunit OS=Mus musculus OX=10090 GN=Farsb PE=1 SV=2 0 21.063 18 9 10 9 589 65.7 7.12 8 1 9 1 13167957.25 4984313.875 10345248.25 12363822.25 8 3 4 4 cell organization and biogenesis;metabolic process cytoplasm;membrane catalytic activity;metal ion binding;nucleotide binding;RNA binding "Pf03483, Pf03484" 23874 ENSMUSG00000026245.16 Farsb 1 Aminoacyl-tRNA biosynthesis 0 High Q60714 Long-chain fatty acid transport protein 1 OS=Mus musculus OX=10090 GN=Slc27a1 PE=1 SV=1 0 39.524 17 7 10 7 646 71.2 8.38 7 10 565851.6875 2173649.313 46850131.75 1 2 5 metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;membrane;mitochondrion catalytic activity;nucleotide binding;protein binding;transporter activity "Pf00501, Pf13193" 26457 ENSMUSG00000031808.7 Slc27a1 8 Transport of fatty acids PPAR signaling pathway; Insulin resistance 0 High Q8R2Z5 von Willebrand factor A domain-containing protein 1 OS=Mus musculus OX=10090 GN=Vwa1 PE=1 SV=1 0 36.082 27 6 10 6 415 44.7 6.54 6 2 1 7 2 1 17397037.25 5423765.375 7553405.5 5 3 3 cell organization and biogenesis;response to stimulus extracellular protein binding "Pf00041, Pf00092, Pf13519" 246228 ENSMUSG00000042116.3 Vwa1 4 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation 0 High P60335 Poly(rC)-binding protein 1 OS=Mus musculus OX=10090 GN=Pcbp1 PE=1 SV=1 0 11.421 12 3 10 1 356 37.5 7.09 3 2 2 5 2 3 2445214.5 2437392.75 4447739 9056668 1 1 1 1 metabolic process;regulation of biological process cytoplasm;cytosol;membrane;nucleus DNA binding;protein binding;RNA binding;translation regulator activity "Pf00013, Pf13014" 23983 ENSMUSG00000051695.6 Pcbp1 6 mRNA Splicing - Major Pathway Spliceosome 0 High Q6P5E4 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Mus musculus OX=10090 GN=Uggt1 PE=1 SV=4 0 37.972 8 9 10 9 1551 176.3 5.62 9 10 4276881 1 metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;organelle lumen catalytic activity;protein binding Pf06427 320011 ENSMUSG00000037470.14 Uggt1 1 ER Quality Control Compartment (ERQC) Protein processing in endoplasmic reticulum 0 High A0A075B5M1 Immunoglobulin kappa variable 4-63 OS=Mus musculus OX=10090 GN=Igkv4-63 PE=1 SV=1 0 30.944 48 3 10 2 95 10.2 5.87 3 1 2 1 3 2 3 2 7887206.25 5367913.25 4875470 4191040 1 1 1 1 "Pf00047, Pf07679, Pf07686" ENSMUSG00000076550.3 6 0 High Q00PI9 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Mus musculus OX=10090 GN=Hnrnpul2 PE=1 SV=2 0 11.156 9 6 10 6 745 84.9 4.89 4 2 1 2 5 2 1 2 22876827.13 25745143.75 15306746.63 10880709.5 5 4 4 2 membrane;nucleus protein binding;RNA binding "Pf00622, Pf02037, Pf13671" 68693 ENSMUSG00000071659.3 Hnrnpul2 19 0 High Q62093 Serine/arginine-rich splicing factor 2 OS=Mus musculus OX=10090 GN=Srsf2 PE=1 SV=4 0 9.459 19 5 10 5 221 25.5 11.85 1 1 5 1 2 1 6 1 3807983.438 18376691 49655602.75 16850103.75 2 3 5 2 metabolic process;regulation of biological process;response to stimulus cytosol;nucleus;spliceosomal complex protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 20382 ENSMUSG00000034120.18 Srsf2 11 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript Herpes simplex infection; Spliceosome 0 High A0A0B4J1I1 Immunoglobulin kappa variable 16-104 (Fragment) OS=Mus musculus OX=10090 GN=Igkv16-104 PE=4 SV=1 0 13.536 23 2 10 2 116 12.9 7.08 2 2 1 2 4 3 1 2 20263629.25 14198144 18505714 6858355.5 3 2 2 2 response to stimulus "Pf00047, Pf07679, Pf07686" 381778 ENSMUSG00000076522.2 Igkv16-104 6 0 High A0A0G2JFS5 Immunoglobulin heavy variable 1-69 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-69 PE=4 SV=1 0 15.533 40 3 10 2 117 12.9 7.87 3 2 2 2 4 2 2 2 16639316 6033284 16049219 6471753 2 1 2 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000094502.5 12 0 High P82349 Beta-sarcoglycan OS=Mus musculus OX=10090 GN=Sgcb PE=1 SV=1 0 34.873 31 6 10 6 320 34.9 8.6 6 10 465139.5313 2035906.625 29747312 1 1 4 Met-loss+Acetyl [N-Term] cell organization and biogenesis cytoplasm;cytoskeleton;membrane Pf04790 24051 ENSMUSG00000029156.11 Sgcb 5 Hypertrophic cardiomyopathy (HCM); Arrhythmogenic right ventricular cardiomyopathy (ARVC); Dilated cardiomyopathy; Viral myocarditis 0 High O89023 Tripeptidyl-peptidase 1 OS=Mus musculus OX=10090 GN=Tpp1 PE=1 SV=2 0 31.448 18 5 10 5 562 61.3 6.57 4 3 6 4 353879.4375 28394160.34 21451237.63 1 3 4 cell differentiation;cell organization and biogenesis;metabolic process mitochondrion;vacuole catalytic activity;metal ion binding;protein binding "Pf00082, Pf09286" 12751 ENSMUSG00000030894.5 Tpp1 7 Lysosome 0 High P16546 "Spectrin alpha chain, non-erythrocytic 1 OS=Mus musculus OX=10090 GN=Sptan1 PE=1 SV=4" 0 24.465 6 10 10 10 2472 284.4 5.33 10 10 8447793.25 8 cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton;membrane metal ion binding;protein binding "Pf00018, Pf00036, Pf00435, Pf07653, Pf08239, Pf08726, Pf12128, Pf13405, Pf13499, Pf14604" 20740 ENSMUSG00000057738.13 Spna2; Sptan1 2 NCAM signaling for neurite out-growth; Interaction between L1 and Ankyrins; COPI-mediated anterograde transport; Neutrophil degranulation; Interleukin-20 family signaling; RAF/MAP kinase cascade; Caspase-mediated cleavage of cytoskeletal proteins 0 High P27048 Small nuclear ribonucleoprotein-associated protein B OS=Mus musculus OX=10090 GN=Snrpb PE=1 SV=1 0 11.97 16 4 10 4 231 23.6 10.9 1 1 4 2 2 6 3405161.094 10159036.25 26752442.25 11030874.25 3 2 4 3 cell organization and biogenesis;metabolic process cytoplasm;cytosol;nucleus;spliceosomal complex protein binding;RNA binding Pf01423 20638 ENSMUSG00000027404.15 Snrpb 2 mRNA Splicing - Minor Pathway; Cleavage of Growing Transcript in the Termination Region ; mRNA Splicing - Major Pathway; snRNP Assembly; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs; SLBP independent Processing of Histone Pre-mRNAs Spliceosome; Systemic lupus erythematosus 0 High Q61733 "28S ribosomal protein S31, mitochondrial OS=Mus musculus OX=10090 GN=Mrps31 PE=1 SV=1" 0 22.217 15 5 10 5 384 43.9 8.51 4 3 1 5 4 1 195964.7656 11680474.5 11643230.13 12081031.75 1 3 3 3 mitochondrion;ribosome protein binding;RNA binding;structural molecule activity Pf15433 57312 ENSMUSG00000031533.4 Mrps31 8 Mitochondrial translation termination; Mitochondrial translation elongation 0 High A0A1D5RME4 60S ribosomal protein L18a (Fragment) OS=Mus musculus OX=10090 GN=Rpl18a PE=1 SV=1 0 13.063 28 3 10 3 123 14.4 10.61 1 3 2 2 1 4 3 2 12253646.25 12373953.75 16541339.5 3 3 3 metabolic process ribosome structural molecule activity Pf01775 ENSMUSG00000045128.9 8 0 High Q6ZWV7 60S ribosomal protein L35 OS=Mus musculus OX=10090 GN=Rpl35 PE=1 SV=1 0 8.184 26 3 10 3 123 14.5 11.05 2 2 2 2 2 3 2 3 4779308.625 14233338.5 9495379 11535659 3 3 2 2 metabolic process;response to stimulus membrane;ribosome RNA binding;structural molecule activity Pf00831 66489 ENSMUSG00000078193.2; ENSMUSG00000062997.6 Rpl35 2; 1 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High A0A2R8VHC0 Alpha-galactosidase (Fragment) OS=Mus musculus OX=10090 GN=Naga PE=1 SV=1 0 25.94 27 6 10 1 237 27 5.25 2 6 2 8 5157768 1 Met-loss [N-Term] 0 High A0A1Y7VN19 Dehydrogenase/reductase SDR family member 7 (Fragment) OS=Mus musculus OX=10090 GN=Dhrs7 PE=1 SV=1 0 30.334 25 6 10 6 362 40.7 8.32 6 10 2588732.656 1844295.125 1721352.625 35003104 4 1 1 5 metabolic process catalytic activity "Pf00106, Pf08659, Pf13561" 0 High P86048 60S ribosomal protein L10-like OS=Mus musculus OX=10090 GN=Rpl10l PE=2 SV=1 0 16.695 18 4 10 4 214 24.5 10.11 1 1 3 4 1 1 4 4 1924073.375 25706481 28361277 35651935.25 2 4 4 4 cell organization and biogenesis;metabolic process membrane;nucleus;ribosome RNA binding;structural molecule activity Pf00252 238217 ENSMUSG00000060499.7 Rpl10l 12 0 High P62849 40S ribosomal protein S24 OS=Mus musculus OX=10090 GN=Rps24 PE=1 SV=1 0 15.03 29 4 9 4 133 15.4 10.78 2 1 1 4 3 1 1 4 2498423.188 8929881.25 9584049 10940943 3 3 3 3 metabolic process membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity Pf01282 20088; 102642752 ENSMUSG00000025290.16 Rps24; LOC677113; LOC102642752 14; 16 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High Q00612 Glucose-6-phosphate 1-dehydrogenase X OS=Mus musculus OX=10090 GN=G6pdx PE=1 SV=3 0 19.685 16 7 9 7 515 59.2 6.49 7 2 7 2 11732788.78 6161926 7 3 Met-loss+Acetyl [N-Term] metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;nucleus catalytic activity;nucleotide binding;protein binding "Pf00479, Pf02781" 14381 ENSMUSG00000031400.10 G6pdx X Pentose phosphate pathway (hexose monophosphate shunt); TP53 Regulates Metabolic Genes Glutathione metabolism; Metabolic pathways; Pentose phosphate pathway; Carbon metabolism; Central carbon metabolism in cancer 0 High Q99K48 Non-POU domain-containing octamer-binding protein OS=Mus musculus OX=10090 GN=Nono PE=1 SV=3 0 7.336 9 4 9 3 473 54.5 8.95 4 1 1 1 5 1 2 1 2898652 1922901.125 3 1 defense response;metabolic process;regulation of biological process;response to stimulus membrane;nucleus DNA binding;protein binding;RNA binding "Pf00076, Pf08075, Pf13893, Pf14259" 53610 ENSMUSG00000031311.17 Nono X 0 High A0A0B4J1K5 Immunoglobulin lambda variable 3 (Fragment) OS=Mus musculus OX=10090 GN=Iglv3 PE=4 SV=1 0.003 3.045 8 1 9 1 122 13.4 5.76 1 1 1 1 1 2 2 4 7447781.5 69922600 143800544 54971252 1 1 1 1 response to stimulus "Pf07679, Pf07686" 404743 ENSMUSG00000076939.2 Iglv3; LOC102641542 16 0 High Q6IME9 "Keratin, type II cytoskeletal 72 OS=Mus musculus OX=10090 GN=Krt72 PE=3 SV=1" 0 6.796 4 3 9 1 520 56.7 7.4 2 1 2 5 2 2 1230514 1592683.375 3922607.5 1 1 1 catalytic activity;motor activity;protein binding;structural molecule activity "Pf00038, Pf01576, Pf09728, Pf12128, Pf13514" 105866 ENSMUSG00000056605.6 Krt72; Krt72-ps 15 Formation of the cornified envelope 0 High Q9D7N3 "28S ribosomal protein S9, mitochondrial OS=Mus musculus OX=10090 GN=Mrps9 PE=1 SV=3" 0 25.947 19 6 9 6 390 44.9 8.81 2 2 4 2 3 4 11750470 15005846.13 23495813 4 5 5 metabolic process mitochondrion;ribosome RNA binding;structural molecule activity Pf00380 69527 ENSMUSG00000060679.14 Mrps9 1 Mitochondrial translation termination; Mitochondrial translation elongation Ribosome 0 High Q91Y06 Protocadherin beta 13 OS=Mus musculus OX=10090 GN=Pcdhb13 PE=2 SV=1 0.003 2.99 3 1 9 1 796 87.5 4.86 1 1 8 1 3278741662 1693535411 1662851345 1643181431 1 1 1 1 cell communication;cell organization and biogenesis membrane metal ion binding "Pf00028, Pf08266" 93884 ENSMUSG00000047307.2 Pcdhb13 18 0 High P18529 Ig heavy chain V region 5-76 OS=Mus musculus OX=10090 PE=1 SV=1 0 4.894 15 2 9 1 117 13 8.91 2 1 1 4 2 3 2924757.75 1298205.25 1 1 Pf07686 0 High Q9R013 Cathepsin F OS=Mus musculus OX=10090 GN=Ctsf PE=1 SV=1 0 23.807 13 4 9 4 462 51.6 6.55 4 1 8 1 714249.7266 53375703.5 12418164.5 3 4 3 metabolic process vacuole catalytic activity "Pf00112, Pf08246" 56464 ENSMUSG00000083282.2 Ctsf 19 MHC class II antigen presentation Lysosome; Apoptosis 0 High Q9DCT5 Stromal cell-derived factor 2 OS=Mus musculus OX=10090 GN=Sdf2 PE=1 SV=1 0 20.881 29 6 9 6 211 23.1 7.33 6 9 248169824 135053432 96471464 220869865.3 1 1 1 6 metabolic process;response to stimulus extracellular;membrane catalytic activity Pf02815 20316 Sdf2 11 0 High O55142 60S ribosomal protein L35a OS=Mus musculus OX=10090 GN=Rpl35a PE=1 SV=2 0 9.42 38 5 9 5 110 12.5 10.89 1 2 2 4 1 2 2 4 1179910.5 8087943.75 11314555.5 12539770.5 1 2 3 3 metabolic process membrane;mitochondrion;ribosome RNA binding;structural molecule activity Pf01247 100043423; 57808; 100042363; 100302576; 100040169; 100046034; 100048620 ENSMUSG00000060636.13 Rpl35a-ps4; Rpl35a; Rpl35a-ps2; Gm10243; Rpl35a-ps5; LOC100862595; Gm14279; LOC100048620 2; 16; 1; 6; 5 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High E0CX32 Coiled-coil domain-containing protein 85A OS=Mus musculus OX=10090 GN=Ccdc85a PE=1 SV=1 0 19.29 12 6 9 6 545 59.6 8.68 1 5 3 1 5 3 3807550.19 9379790.25 10343318.25 3 3 3 Pf10226 216613 ENSMUSG00000032878.16 Ccdc85a 11 0 High P52480 Pyruvate kinase PKM OS=Mus musculus OX=10090 GN=Pkm PE=1 SV=4 0 18.431 18 6 9 6 531 57.8 7.47 4 1 3 5 1 3 7713372 5294602.25 1082451.5 23851595.5 4 3 1 4 Met-loss [N-Term] cell death;cell organization and biogenesis;metabolic process;response to stimulus cytoplasm;cytosol;mitochondrion;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding;RNA binding "Pf00224, Pf02887" 18746 ENSMUSG00000032294.17 Pkm 9 Neutrophil degranulation; Glycolysis Pyruvate metabolism; Type II diabetes mellitus; Metabolic pathways; Biosynthesis of amino acids; Purine metabolism; Glycolysis / Gluconeogenesis; Carbon metabolism; Central carbon metabolism in cancer; Glucagon signaling pathway; Viral carcinogenesis 0 High A0A1B0GS68 60S ribosomal protein L13a OS=Mus musculus OX=10090 GN=Gm45713 PE=2 SV=1 0 6.651 6 3 9 3 446 50.8 10.23 1 2 3 2 1 3 3 2 5771043.031 22394833 20404316 32499632.5 3 3 3 3 metabolic process;regulation of biological process membrane;ribosome protein binding;structural molecule activity "Pf00572, Pf02947" ENSMUSG00000089989.10 7 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane 0 High D3Z4R1 Probable ATP-dependent DNA helicase HFM1 OS=Mus musculus OX=10090 GN=Hfm1 PE=3 SV=2 0.009 1.822 0 1 9 1 1434 161.3 7.85 1 1 1 1 3 2 2 2 34374040 29583790 23465678 40879568 1 1 1 1 cell differentiation;metabolic process cytoplasm catalytic activity;DNA binding;nucleotide binding "Pf00270, Pf00271, Pf02889, Pf04851" 330149 ENSMUSG00000043410.16 Hfm1 5 0 High Q9WTX5 S-phase kinase-associated protein 1 OS=Mus musculus OX=10090 GN=Skp1 PE=1 SV=3 0 24.031 55 6 9 6 163 18.7 4.54 6 9 1142935.375 1483045.375 1201724.5 26379410.72 1 1 1 4 cell organization and biogenesis;metabolic process cytoplasm;cytosol;nucleus catalytic activity;protein binding "Pf01466, Pf03931" 21402 ENSMUSG00000036309.14 Skp1a 11 NIK-->noncanonical NF-kB signaling; Degradation of beta-catenin by the destruction complex; Prolactin receptor signaling; SCF-beta-TrCP mediated degradation of Emi1; Regulation of RUNX2 expression and activity; SCF(Skp2)-mediated degradation of p27/p21; Neddylation; GLI3 is processed to GLI3R by the proteasome; Dectin-1 mediated noncanonical NF-kB signaling; Activation of NF-kappaB in B cells; Activated TLR4 signalling; Antigen processing: Ubiquitination & Proteasome degradation; Degradation of GLI1 by the proteasome; FCERI mediated NF-kB activation; Regulation of PLK1 Activity at G2/M Transition; Downstream TCR signaling; Cyclin D associated events in G1; Interleukin-1 family signaling; Iron uptake and transport; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; MAP3K8 (TPL2)-dependent MAPK1/3 activation Herpes simplex infection; Wnt signaling pathway; Ubiquitin mediated proteolysis; Circadian rhythm; Oocyte meiosis; Cell cycle; TGF-beta signaling pathway; Protein processing in endoplasmic reticulum 0 High Q8C0L0 Thioredoxin-related transmembrane protein 4 OS=Mus musculus OX=10090 GN=Tmx4 PE=1 SV=2 0 27.763 18 5 9 5 335 37.1 4.37 5 9 76741261 5 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport endoplasmic reticulum;membrane catalytic activity Pf00085 52837 ENSMUSG00000034723.11 Tmx4 2 0 High A0A1L1SSC7 Tetratricopeptide repeat domain 13 OS=Mus musculus OX=10090 GN=Ttc13 PE=1 SV=1 0 33.445 16 9 9 9 844 95 6.96 9 9 1735816.25 21621924.75 1 4 protein binding "Pf00515, Pf07719, Pf13181, Pf13414, Pf13424, Pf13432, Pf14559" 234875 ENSMUSG00000037300.18 Ttc13 8 0 High A0A140T8P3 Immunoglobulin kappa chain variable 15-103 (Fragment) OS=Mus musculus OX=10090 GN=Igkv15-103 PE=4 SV=2 0 8.091 10 1 9 1 115 12.5 7.8 1 1 1 1 3 1 3 2 19013458 13195250 35923238 35338038 1 1 1 1 Pf07686 692169 ENSMUSG00000076523.2 Igkv15-103 6 0 High Q9CY27 Very-long-chain enoyl-CoA reductase OS=Mus musculus OX=10090 GN=Tecr PE=1 SV=1 0 14.154 18 6 9 6 308 36.1 9.55 6 9 686004.125 1859661.75 1443754.75 73233519.5 1 1 1 6 metabolic process cytoplasm;endoplasmic reticulum;membrane;nucleus catalytic activity Pf02544 106529 ENSMUSG00000031708.16 Tecr 8 Synthesis of very long-chain fatty acyl-CoAs Fatty acid metabolism; Fatty acid elongation; Biosynthesis of unsaturated fatty acids 0 High Q9D9Q6 Calreticulin-3 OS=Mus musculus OX=10090 GN=Calr3 PE=1 SV=2 0 25.611 20 8 9 8 380 44.2 6.43 8 9 39757710 4 cell differentiation;metabolic process endoplasmic reticulum;organelle lumen metal ion binding;protein binding Pf00262 73316 ENSMUSG00000019732.14 Calr3 8 0 High Q91WS0 CDGSH iron-sulfur domain-containing protein 1 OS=Mus musculus OX=10090 GN=Cisd1 PE=1 SV=1 0 13.744 34 3 9 3 108 12.1 9.06 1 2 3 1 2 6 3454688.313 9928768.75 13354767.5 74171170 3 3 3 3 regulation of biological process membrane;mitochondrion metal ion binding;protein binding Pf09360 52637 ENSMUSG00000037710.8 Cisd1 10 0 High Q9DB77 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Mus musculus OX=10090 GN=Uqcrc2 PE=1 SV=1" 0 21.266 20 5 9 5 453 48.2 9.25 2 3 4 2 3 4 4759244.75 14454016.75 1801029.5 20175730.5 4 4 1 4 metabolic process;transport membrane;mitochondrion catalytic activity;metal ion binding;protein binding "Pf00675, Pf05193" 67003 ENSMUSG00000030884.12 Uqcrc2 7 Respiratory electron transport Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 High Q9WVL0 Maleylacetoacetate isomerase OS=Mus musculus OX=10090 GN=Gstz1 PE=1 SV=1 0 32.888 32 5 9 5 216 24.3 7.85 1 5 1 8 48623220 4 metabolic process cytoplasm;mitochondrion catalytic activity;protein binding "Pf00043, Pf02798, Pf13409, Pf13417" 14874 ENSMUSG00000021033.10 Gstz1 12 Phenylalanine and tyrosine catabolism; Glutathione conjugation Metabolic pathways; Tyrosine metabolism 0 High A0A075B5R1 Immunoglobulin heavy variable 5-17 (Fragment) OS=Mus musculus OX=10090 GN=Ighv5-17 PE=1 SV=1 0 7.624 19 2 9 1 117 12.9 8.28 2 1 1 4 2 3 10235076 4907520.5 10999568 2982414.75 1 1 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000095571.2 12 0 High Q8BHN3 Neutral alpha-glucosidase AB OS=Mus musculus OX=10090 GN=Ganab PE=1 SV=1 0 20.103 9 8 9 8 944 106.8 6.06 8 9 23712422.5 4 metabolic process endoplasmic reticulum;Golgi;membrane catalytic activity;protein binding;RNA binding "Pf01055, Pf13802" 14376 Ganab 19 Calnexin/calreticulin cycle Metabolic pathways; N-Glycan biosynthesis; Protein processing in endoplasmic reticulum 0 High P16332 "Methylmalonyl-CoA mutase, mitochondrial OS=Mus musculus OX=10090 GN=Mmut PE=1 SV=2" 0 38.338 15 6 9 6 748 82.8 6.89 2 2 5 2 2 5 3308407.063 6909124.125 16360770.75 3 4 3 metabolic process mitochondrion;organelle lumen catalytic activity;metal ion binding "Pf01642, Pf02310" 17850 ENSMUSG00000023921.8 Mut 17 "Propionyl-CoA catabolism; Cobalamin (Cbl, vitamin B12) transport and metabolism" "Valine, leucine and isoleucine degradation; Metabolic pathways; Propanoate metabolism; Carbon metabolism; Glyoxylate and dicarboxylate metabolism" 0 High P0DP27 Calmodulin-2 OS=Mus musculus OX=10090 GN=Calm2 PE=1 SV=1 0 18.898 27 3 8 3 149 16.8 4.22 1 2 3 2 2 4 5188412.844 4937453 16311376.25 27730751.13 3 1 3 3 regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;nucleus enzyme regulator activity;metal ion binding;protein binding "Pf00036, Pf08726, Pf12763, Pf13202, Pf13405, Pf13499, Pf13833, Pf14658" 12315; 12313; 12314 ENSMUSG00000001175.13; ENSMUSG00000036438.12; ENSMUSG00000019370.10 Calm3; Calm1; Calm2 7; 12; 17 Oxytocin signaling pathway; Dopaminergic synapse; Ras signaling pathway; Insulin signaling pathway; Long-term potentiation; Amphetamine addiction; Tuberculosis; Melanogenesis; Oocyte meiosis; Pertussis; Neurotrophin signaling pathway; cGMP-PKG signaling pathway; Rap1 signaling pathway; Calcium signaling pathway; Salivary secretion; Alzheimer's disease; Alcoholism; cAMP signaling pathway; Vascular smooth muscle contraction; Aldosterone synthesis and secretion; GnRH signaling pathway; Olfactory transduction; Phototransduction; Gastric acid secretion; Renin secretion; Circadian entrainment; Glioma; Estrogen signaling pathway; Glucagon signaling pathway; Phosphatidylinositol signaling system; Adrenergic signaling in cardiomyocytes; Inflammatory mediator regulation of TRP channels 0 High A0A075B5M3 Immunoglobulin kappa variable 4-58 OS=Mus musculus OX=10090 GN=Igkv4-58 PE=1 SV=1 0 5.375 30 2 8 1 97 10.3 7.28 1 1 1 2 2 2 2 2 23738600 18830708 16916506 10730133 1 1 1 1 Pf07686 ENSMUSG00000095633.2 6 1 High Q8CIZ8 von Willebrand factor OS=Mus musculus OX=10090 GN=Vwf PE=1 SV=2 0 13.216 3 6 8 6 2813 309.1 5.5 6 8 4457729.281 904049.8125 5 1 cell organization and biogenesis;coagulation cytoplasm;endoplasmic reticulum;extracellular protein binding "Pf00092, Pf00093, Pf00094, Pf01826, Pf08742" 22371 Vwf 6 Focal adhesion; Platelet activation; Complement and coagulation cascades; ECM-receptor interaction; PI3K-Akt signaling pathway 0 High Q9CY16 "28S ribosomal protein S28, mitochondrial OS=Mus musculus OX=10090 GN=Mrps28 PE=1 SV=1" 0 17.746 32 5 8 5 186 20.5 8.92 3 1 4 3 1 4 422661.125 5114883.188 3934856.813 10214780.5 1 2 2 3 mitochondrion;ribosome RNA binding Pf10246 66230 ENSMUSG00000040269.5 Mrps28 3 Mitochondrial translation termination; Mitochondrial translation elongation 0 High Q9JIK9 "28S ribosomal protein S34, mitochondrial OS=Mus musculus OX=10090 GN=Mrps34 PE=1 SV=1" 0 9.769 15 3 8 3 218 25.8 10.43 2 2 3 2 2 4 474955.5 10647746.5 9152649.25 19132039 1 2 2 2 cell organization and biogenesis;metabolic process mitochondrion;ribosome structural molecule activity 79044 ENSMUSG00000038880.13 Mrps34 17 Mitochondrial translation termination; Mitochondrial translation elongation 0 High O35083 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha OS=Mus musculus OX=10090 GN=Agpat1 PE=1 SV=1 0 19.157 18 3 8 3 285 31.7 9.14 1 1 3 1 1 6 248823.1641 210466.875 192179.75 24761819.5 2 1 1 3 metabolic process;regulation of biological process endoplasmic reticulum;membrane catalytic activity Pf01553 55979 Agpat1 17 Phospholipase D signaling pathway; Fat digestion and absorption; Metabolic pathways; Glycerophospholipid metabolism; Glycerolipid metabolism 0 High Q99M74 "Keratin, type II cuticular Hb2 OS=Mus musculus OX=10090 GN=Krt82 PE=1 SV=2" 0.006 2.129 2 2 8 2 516 57.1 6.25 1 2 1 1 1 2 3 2 30607131.38 93593899 33341434 95938366.5 2 2 1 2 structural molecule activity Pf00038 114566 ENSMUSG00000049548.8 Krt82 15 Formation of the cornified envelope 0 High Q9WTI7 Unconventional myosin-Ic OS=Mus musculus OX=10090 GN=Myo1c PE=1 SV=2 0 12.097 5 5 8 5 1063 121.9 9.35 5 1 1 1 5 1 1 1 4261020.688 2579965.5 3656288.375 11171612.25 5 2 2 4 cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;membrane;nucleus catalytic activity;motor activity;nucleotide binding;protein binding "Pf00063, Pf06017" 17913 ENSMUSG00000017774.19 Myo1c 11 Regulation of actin dynamics for phagocytic cup formation; B-WICH complex positively regulates rRNA expression 0 High Q9EQH2 Endoplasmic reticulum aminopeptidase 1 OS=Mus musculus OX=10090 GN=Erap1 PE=1 SV=2 0 25.897 9 8 8 8 930 106.5 6.2 8 8 730130.3125 1958162.875 35884109.5 1 1 4 cell communication;metabolic process;regulation of biological process;response to stimulus cytoplasm;endoplasmic reticulum;extracellular;membrane;organelle lumen catalytic activity;metal ion binding;protein binding "Pf01433, Pf11838, Pf13485" 80898 ENSMUSG00000021583.6 Erap1 13 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC" 0 High Q8VEK0 Cell cycle control protein 50A OS=Mus musculus OX=10090 GN=Tmem30a PE=1 SV=1 0 18.157 13 4 8 4 364 41 8.37 4 8 521085.5938 39437524 1 2 cell organization and biogenesis;regulation of biological process;transport endoplasmic reticulum;Golgi;membrane protein binding;transporter activity Pf03381 69981 ENSMUSG00000032328.12 Tmem30a 9 Neutrophil degranulation 0 High Q8R429 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 OS=Mus musculus OX=10090 GN=Atp2a1 PE=1 SV=1 0 20.963 9 8 8 1 994 109.4 5.22 8 8 cell organization and biogenesis;cellular homeostasis;regulation of biological process;response to stimulus;transport endoplasmic reticulum;membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding;transporter activity "Pf00122, Pf00689, Pf00690, Pf00702, Pf08282, Pf12710, Pf13246" 11937 ENSMUSG00000030730.12 Atp2a1 7 Ion transport by P-type ATPases; Ion homeostasis; Reduction of cytosolic Ca++ levels Pancreatic secretion; cGMP-PKG signaling pathway; Calcium signaling pathway; Alzheimer's disease 0 High Q9D8T0 Protein FAM3A OS=Mus musculus OX=10090 GN=Fam3a PE=2 SV=1 0 24.043 32 5 8 5 230 25.4 8.44 5 8 29545095 3 defense response;response to stimulus extracellular;membrane 66294 ENSMUSG00000031399.15 Fam3a X 0 High P82347 Delta-sarcoglycan OS=Mus musculus OX=10090 GN=Sgcd PE=1 SV=1 0 11.183 13 4 8 4 289 32.1 9.1 3 4 3 5 721861.9063 14982414.88 21671671.25 2 3 3 cell organization and biogenesis cytoplasm;cytoskeleton;membrane protein binding Pf04790 24052 ENSMUSG00000020354.15 Sgcd 11 Hypertrophic cardiomyopathy (HCM); Arrhythmogenic right ventricular cardiomyopathy (ARVC); Dilated cardiomyopathy; Viral myocarditis 0 High Q9CYD3 Cartilage-associated protein OS=Mus musculus OX=10090 GN=Crtap PE=1 SV=3 0 22.391 16 6 8 6 400 46.1 5.71 6 8 45225138.5 5 metabolic process;regulation of biological process endoplasmic reticulum;extracellular protein binding 56693 ENSMUSG00000032431.6 Crtap 9 Collagen biosynthesis and modifying enzymes 0 High Q9D880 Mitochondrial import inner membrane translocase subunit TIM50 OS=Mus musculus OX=10090 GN=Timm50 PE=1 SV=1 0 17.015 14 5 8 5 353 39.8 8.13 1 1 5 1 1 6 1234054.625 4738797.375 10092315.75 59974905 2 2 4 5 cell organization and biogenesis;metabolic process;transport membrane;mitochondrion catalytic activity;protein binding Pf03031 66525 ENSMUSG00000003438.17 Timm50 7 0 High P56391 Cytochrome c oxidase subunit 6B1 OS=Mus musculus OX=10090 GN=Cox6b1 PE=1 SV=2 0 9.874 37 4 8 4 86 10.1 8.72 3 3 2 3 3 2 4945354.5 7053037.75 6585731.625 21041561.5 4 3 3 4 membrane;mitochondrion catalytic activity;transporter activity Pf02297 110323 ENSMUSG00000036751.7 Cox6b1 7 Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 High A0A075B5M2 Immunoglobulin kappa chain variable 4-61 OS=Mus musculus OX=10090 GN=Igkv4-61 PE=4 SV=7 0 4.979 31 2 8 1 94 10.1 7.96 1 1 2 1 2 2 3 1 5941220.5 6209424.5 1 1 ENSMUSG00000076552.3 6 0 High Q9WTP6 "Adenylate kinase 2, mitochondrial OS=Mus musculus OX=10090 GN=Ak2 PE=1 SV=5" 0 21.144 27 4 8 4 239 26.5 7.39 4 1 1 1 4 1 1 2 4381817.688 2824528.25 3466942 6126929.75 4 2 2 2 metabolic process cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;nucleotide binding "Pf00406, Pf05191" 11637 ENSMUSG00000028792.14 Ak2 4 Interconversion of nucleotide di- and triphosphates Thiamine metabolism; Metabolic pathways; Purine metabolism 0 High P01679 Ig kappa chain V-VI region J539 OS=Mus musculus OX=10090 PE=1 SV=1 0 9.295 37 3 8 2 107 11.5 8.46 3 1 1 5 1 2 5299264.75 1751902.625 1918527.375 2 1 1 Pf07686 0 High A0A6I8MX27 L-lactate dehydrogenase OS=Mus musculus OX=10090 GN=Ldhb PE=1 SV=1 0 9.625 10 3 8 3 341 37.3 6.25 1 1 2 2 2 1 3 2 4713158.375 6060427 6691800.875 10219270.75 3 3 3 3 0 High Q9Z2V4 "Phosphoenolpyruvate carboxykinase, cytosolic [GTP] OS=Mus musculus OX=10090 GN=Pck1 PE=1 SV=1" 0 17.916 9 6 8 6 622 69.3 6.6 6 8 1252381.813 27363048 3 4 cell communication;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol catalytic activity;metal ion binding;nucleotide binding Pf00821 18534 ENSMUSG00000027513.11 Pck1 2 Gluconeogenesis FoxO signaling pathway; PPAR signaling pathway; Pyruvate metabolism; Citrate cycle (TCA cycle); Insulin signaling pathway; Metabolic pathways; Insulin resistance; Glycolysis / Gluconeogenesis; Proximal tubule bicarbonate reclamation; Adipocytokine signaling pathway; PI3K-Akt signaling pathway; AMPK signaling pathway; Glucagon signaling pathway 0 High O70302 Cell death activator CIDE-A OS=Mus musculus OX=10090 GN=Cidea PE=1 SV=2 0 13.379 24 6 8 6 217 24.7 9.36 1 6 1 7 1164921.938 2510020.75 1659849.125 36763393 3 2 1 5 cell death;metabolic process;regulation of biological process;response to stimulus cytoplasm;mitochondrion;nucleus protein binding Pf02017 12683 ENSMUSG00000024526.8 Cidea 18 Lipid particle organization 0 High P16045 Galectin-1 OS=Mus musculus OX=10090 GN=Lgals1 PE=1 SV=3 0 16.962 40 4 8 4 135 14.9 5.49 4 1 1 6 1 1 3021337.5 2075007.375 2724353.25 7789809.125 3 1 2 3 Met-loss+Acetyl [N-Term] cell death;cell differentiation;cellular homeostasis;regulation of biological process;response to stimulus cell surface;cytoplasm;cytosol;extracellular;nucleus protein binding;RNA binding;signal transducer activity Pf00337 16852 ENSMUSG00000068220.5 Lgals1 15 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation 0 High A0A0B4J1J1 Immunoglobulin kappa chain variable 5-45 (Fragment) OS=Mus musculus OX=10090 GN=Igkv5-45 PE=1 SV=1 0 12.256 23 2 8 1 115 12.7 7.28 2 1 1 1 2 1 2 3 5430013 2132499.5 4991208.5 1 1 1 response to stimulus "Pf00047, Pf07679, Pf07686, Pf13927" 545850 ENSMUSG00000094094.2 Igkv5-45 6 0 High D3YTT4 "Isobutyryl-CoA dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Acad8 PE=1 SV=1" 0 15.949 14 4 8 4 413 45 8.02 1 1 2 4 1 1 2 4 8137393.281 13666684.75 13124468.75 21847856.38 3 3 3 3 metabolic process catalytic activity;nucleotide binding "Pf00441, Pf02770, Pf02771, Pf08028" ENSMUSG00000031969.16 9 Branched-chain amino acid catabolism 0 High P50171 (3R)-3-hydroxyacyl-CoA dehydrogenase OS=Mus musculus OX=10090 GN=Hsd17b8 PE=1 SV=2 0 29.435 25 4 8 4 259 26.6 6.54 4 1 3 4 1 3 4718377.625 7604927 9008250.75 29271391 2 2 2 2 cell organization and biogenesis;metabolic process membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf00106, Pf08659, Pf13561" 14979 ENSMUSG00000073422.10 H2-Ke6 17 Fatty acyl-CoA biosynthesis Steroid hormone biosynthesis; Metabolic pathways 0 High Q2HXL6 ER degradation-enhancing alpha-mannosidase-like protein 3 OS=Mus musculus OX=10090 GN=Edem3 PE=1 SV=2 0 25.427 9 6 8 6 931 104.1 5.06 6 8 58995764.5 5 metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;membrane;organelle lumen catalytic activity;metal ion binding "Pf01532, Pf02225" 66967 ENSMUSG00000043019.12 Edem3 1 ER Quality Control Compartment (ERQC) Protein processing in endoplasmic reticulum 0 High A0A0U1RNL7 Protein-serine/threonine kinase OS=Mus musculus OX=10090 GN=Bckdk PE=1 SV=1 0 11.839 16 4 8 4 335 38 9.42 4 1 2 5 1 2 11956106.75 1187443 8866087.625 8674831.5 4 1 3 3 metabolic process mitochondrion catalytic activity Pf10436 ENSMUSG00000030802.14 7 0 High Q2TPA8 Hydroxysteroid dehydrogenase-like protein 2 OS=Mus musculus OX=10090 GN=Hsdl2 PE=1 SV=1 0 11.721 17 4 8 4 490 54.2 6.74 3 1 1 3 3 1 1 3 4996171.313 1683145.375 5105115.875 27288881.5 4 1 2 4 metabolic process membrane;mitochondrion catalytic activity "Pf00106, Pf02036, Pf14864" 72479 ENSMUSG00000028383.17 Hsdl2 4 0 High P15331 Peripherin OS=Mus musculus OX=10090 GN=Prph PE=1 SV=2 0 11.758 11 5 8 2 475 54.2 5.52 4 1 1 2 4 1 1 2 1504602 1063338.75 2 1 cell organization and biogenesis membrane protein binding;structural molecule activity "Pf00038, Pf04732" 19132 Prph 15 0 High A0A075B664 Immunoglobulin lambda variable 2 OS=Mus musculus OX=10090 GN=Iglv2 PE=1 SV=1 0 24.757 36 2 8 2 116 12.2 5.74 2 1 1 6 1 1 124852616 85932495.75 133155664 16660925 2 2 1 1 Pf07686 ENSMUSG00000076940.3 16 0 High Q6PCP5 Mitochondrial fission factor OS=Mus musculus OX=10090 GN=Mff PE=1 SV=1 0 21.566 38 6 8 6 291 32.9 6.83 6 2 6 2 cell organization and biogenesis;regulation of biological process;transport membrane;mitochondrion protein binding Pf05644 75734 ENSMUSG00000026150.14 Mff 1 0 High P03953 Complement factor D OS=Mus musculus OX=10090 GN=Cfd PE=1 SV=1 0 25.055 23 4 8 4 259 28 6.67 4 8 55167417 3 defense response;metabolic process;regulation of biological process;response to stimulus extracellular catalytic activity "Pf00089, Pf09342" 11537 ENSMUSG00000061780.6 Cfd 10 Alternative complement activation; Platelet degranulation ; Neutrophil degranulation Staphylococcus aureus infection; Complement and coagulation cascades 0 High P01665 Ig kappa chain V-III region PC 7043 OS=Mus musculus OX=10090 PE=1 SV=1 0 25.83 53 3 8 2 111 12 4.61 2 1 2 4 1 3 7019229.5 1932287.875 3975117.75 4211802.5 2 1 1 1 "Pf00047, Pf07679, Pf07686" 626347 Igkv3-4 6 0 High P19783 "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Mus musculus OX=10090 GN=Cox4i1 PE=1 SV=2" 0 7.083 14 3 8 3 169 19.5 9.23 2 1 3 2 2 4 3590069.313 11808228.38 5304547.375 22708198 3 3 2 2 metabolic process;response to stimulus;transport membrane;mitochondrion;nucleus catalytic activity;transporter activity Pf02936 12857 ENSMUSG00000031818.12 Cox4i1 8 Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 High Q8C165 N-fatty-acyl-amino acid synthase/hydrolase PM20D1 OS=Mus musculus OX=10090 GN=Pm20d1 PE=1 SV=1 0 23.339 17 6 8 6 503 55.6 6.43 6 8 95427.60156 40615731.5 1 4 metabolic process;regulation of biological process extracellular catalytic activity;metal ion binding "Pf01546, Pf07687" 212933 ENSMUSG00000042251.12 Pm20d1 1 0 High Q9CQU0 Thioredoxin domain-containing protein 12 OS=Mus musculus OX=10090 GN=Txndc12 PE=1 SV=1 0 12.562 32 6 7 6 170 19 5.26 6 7 82482973.5 4 cell differentiation;cellular homeostasis;metabolic process;regulation of biological process endoplasmic reticulum;organelle lumen catalytic activity "Pf00085, Pf13098, Pf13899" 66073 ENSMUSG00000028567.8 Txndc12 4 Glutathione metabolism 0 High D3YYS6 Monoglyceride lipase OS=Mus musculus OX=10090 GN=Mgll PE=1 SV=1 0 23.175 23 6 7 6 331 36.6 7.21 6 7 1055995.844 3393408.75 31881044.5 2 2 5 metabolic process catalytic activity "Pf00561, Pf00756, Pf00975, Pf01764, Pf12146, Pf12695, Pf12697" ENSMUSG00000033174.17 6 0 High Q62318 Transcription intermediary factor 1-beta OS=Mus musculus OX=10090 GN=Trim28 PE=1 SV=3 0 18.482 11 5 7 5 834 88.8 5.77 1 4 2 1 4 2 3818854.063 7621257.125 3589504 3 3 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus chromosome;nucleus catalytic activity;DNA binding;metal ion binding;protein binding;RNA binding "Pf00628, Pf00643" 21849 ENSMUSG00000005566.14 Trim28 7 Generic Transcription Pathway 0 High A0A075B5Q6 Immunoglobulin heavy variable 5-9-1 OS=Mus musculus OX=10090 GN=Ighv5-9-1 PE=1 SV=1 0 10.138 33 3 7 3 116 13.1 8.87 2 2 1 3 2 2 11509769.25 16381824 22019262 9352369.5 3 2 2 2 ENSMUSG00000095210.2 12 0 High P70372 ELAV-like protein 1 OS=Mus musculus OX=10090 GN=Elavl1 PE=1 SV=2 0 12.022 22 6 7 6 326 36.1 9.04 3 4 3 4 7405642.125 4179356.125 10490021.88 6306830.5 3 2 3 2 Met-loss+Acetyl [N-Term] regulation of biological process cytoplasm;cytosol;membrane;nucleus protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 15568 ENSMUSG00000040028.10 Elavl1 8 mRNA Splicing - Major Pathway; HuR (ELAVL1) binds and stabilizes mRNA AMPK signaling pathway 0 High P15208 Insulin receptor OS=Mus musculus OX=10090 GN=Insr PE=1 SV=2 0 16.191 5 7 7 6 1372 155.5 5.95 7 7 48212.82422 18669459.25 1 4 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytosol;endosome;membrane;nucleus;organelle lumen catalytic activity;nucleotide binding;protein binding;receptor activity;signal transducer activity "Pf00041, Pf00069, Pf00757, Pf01030, Pf07714, Pf14843" 16337 ENSMUSG00000005534.10 Insr 8 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; IRS activation; Signal attenuation; Insulin receptor recycling" FoxO signaling pathway; mTOR signaling pathway; Phospholipase D signaling pathway; Type II diabetes mellitus; Ras signaling pathway; Regulation of lipolysis in adipocytes; Ovarian steroidogenesis; Insulin signaling pathway; Insulin resistance; Longevity regulating pathway; Adherens junction; Non-alcoholic fatty liver disease (NAFLD); cGMP-PKG signaling pathway; Rap1 signaling pathway; HIF-1 signaling pathway; PI3K-Akt signaling pathway; AMPK signaling pathway; Longevity regulating pathway - multiple species; Aldosterone-regulated sodium reabsorption 1 High P38060 "Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Mus musculus OX=10090 GN=Hmgcl PE=1 SV=2" 0 17.476 20 4 7 4 325 34.2 8.41 4 1 1 5 1 1 1933866.063 951190.25 570432.125 3 1 1 cell organization and biogenesis;metabolic process;response to stimulus membrane;mitochondrion;organelle lumen catalytic activity;metal ion binding;protein binding Pf00682 15356 ENSMUSG00000028672.13 Hmgcl 4 Synthesis of Ketone Bodies "Valine, leucine and isoleucine degradation; Metabolic pathways; Butanoate metabolism; Synthesis and degradation of ketone bodies; Peroxisome" 0 Medium Q8R4D5 Transient receptor potential cation channel subfamily M member 8 OS=Mus musculus OX=10090 GN=Trpm8 PE=1 SV=3 0.021 1.331 1 1 7 1 1104 127.6 6.92 1 1 1 1 2 2 1 2 29925550 14298540 11191388 17377414 1 1 1 1 cell organization and biogenesis;cellular homeostasis;response to stimulus;transport membrane catalytic activity;protein binding;transporter activity "Pf00520, Pf01757" 171382 ENSMUSG00000036251.16 Trpm8 1 TRP channels Inflammatory mediator regulation of TRP channels 0 High A0A075B5Q2 Immunoglobulin heavy variable 5-9 (Fragment) OS=Mus musculus OX=10090 GN=Ighv5-9 PE=4 SV=1 0 6.619 19 2 7 1 117 12.8 8.92 2 1 2 1 3 1 2 1 1599668.25 2485808.75 5817239 1 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000095285.2 LOC674130 12 0 High A0A075B5W3 Immunoglobulin heavy variable 1-53 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-53 PE=4 SV=1 0 12.655 42 3 7 1 117 12.8 8.88 2 1 2 1 3 1 2 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000093894.1 AB069917 12 0 High Q9QZN4 F-box only protein 6 OS=Mus musculus OX=10090 GN=Fbxo6 PE=1 SV=1 0 13.809 17 5 7 5 295 34.5 8.18 5 7 19442783.5 2 metabolic process;response to stimulus cytoplasm catalytic activity;protein binding "Pf00646, Pf04300, Pf12937" 50762 ENSMUSG00000055401.14 Fbxo6 4 Neddylation; Antigen processing: Ubiquitination & Proteasome degradation Protein processing in endoplasmic reticulum 0 High P01901 "H-2 class I histocompatibility antigen, K-B alpha chain OS=Mus musculus OX=10090 GN=H2-K1 PE=1 SV=1" 0 15.607 19 5 7 2 369 41.3 6.39 5 7 14339153.5 2 defense response;regulation of biological process;response to stimulus cell surface;endoplasmic reticulum;Golgi;membrane protein binding;RNA binding "Pf00129, Pf06623, Pf07654" 14972 ENSMUSG00000061232.15 H2-K1 17 Endocytosis; Herpes simplex infection; Allograft rejection; Epstein-Barr virus infection; Cell adhesion molecules (CAMs); HTLV-I infection; Phagosome; Graft-versus-host disease; Viral myocarditis; Antigen processing and presentation; Type I diabetes mellitus; Natural killer cell mediated cytotoxicity; Autoimmune thyroid disease; Viral carcinogenesis 0 High P08122 Collagen alpha-2(IV) chain OS=Mus musculus OX=10090 GN=Col4a2 PE=1 SV=4 0 8.197 2 3 7 3 1707 167.2 8.48 2 2 1 3 2 2 23681068.38 9792923 12509918.5 4984757.25 3 2 2 2 cell differentiation;metabolic process;regulation of biological process;response to stimulus extracellular structural molecule activity "Pf01391, Pf01413" 12827 ENSMUSG00000031503.13 Col4a2 8 Anchoring fibril formation; Laminin interactions; Crosslinking of collagen fibrils; Collagen chain trimerization; Integrin cell surface interactions; NCAM1 interactions; Collagen degradation; Non-integrin membrane-ECM interactions; Signaling by PDGF AGE-RAGE signaling pathway in diabetic complications; Focal adhesion; Protein digestion and absorption; Small cell lung cancer; Pathways in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway; Amoebiasis 0 High Q80TS5 Zinc finger protein 423 OS=Mus musculus OX=10090 GN=Znf423 PE=1 SV=2 0 16.654 7 6 7 6 1292 145.3 6.95 1 6 1 6 5233234.5 11003688.25 2796247.5 2 3 1 cell differentiation;development;metabolic process;regulation of biological process;response to stimulus nucleus DNA binding;metal ion binding;protein binding 94187 ENSMUSG00000045333.15 Zfp423 8 0 High A0A0R4J0I9 Prolow-density lipoprotein receptor-related protein 1 OS=Mus musculus OX=10090 GN=Lrp1 PE=1 SV=1 0 24.072 2 6 7 6 4545 504.4 5.36 6 7 3994949.25 1 cell proliferation;development;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;endosome;membrane;nucleus metal ion binding;protein binding;receptor activity;RNA binding "Pf00057, Pf00058, Pf07645, Pf12662, Pf14670" 16971 ENSMUSG00000040249.15 Lrp1 10 Signaling by GPCR; Retinoid metabolism and transport; Scavenging of heme from plasma Alzheimer's disease; Malaria 0 High P47955 60S acidic ribosomal protein P1 OS=Mus musculus OX=10090 GN=Rplp1 PE=1 SV=1 0 28.631 29 2 7 2 114 11.5 4.32 1 1 2 1 3 3 1633453.781 2258881.438 2 2 Met-loss+Acetyl [N-Term] metabolic process;regulation of biological process ribosome enzyme regulator activity;structural molecule activity Pf00428 56040 ENSMUSG00000007892.8 Rplp1 9 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q9CXW2 "28S ribosomal protein S22, mitochondrial OS=Mus musculus OX=10090 GN=Mrps22 PE=1 SV=1" 0 8.053 8 3 7 3 359 41.2 8.56 1 2 2 2 1 2 2 2 1054338.813 22525491.5 23415333.75 12634981.5 2 3 3 2 mitochondrion;ribosome structural molecule activity Pf10245 64655 ENSMUSG00000032459.9 Mrps22 9 Mitochondrial translation termination; Mitochondrial translation elongation 0 High E9Q557 Desmoplakin OS=Mus musculus OX=10090 GN=Dsp PE=1 SV=1 0 17.394 2 7 7 7 2883 332.7 6.8 1 6 1 6 1302693.563 1499006 26563213 2 1 3 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane;nucleus catalytic activity;motor activity;protein binding;RNA binding;structural molecule activity "Pf00038, Pf00681, Pf01576, Pf02463, Pf04111, Pf04156, Pf05483, Pf05557, Pf05622, Pf06637, Pf06705, Pf07888, Pf10174, Pf12128" 109620 ENSMUSG00000054889.9 Dsp 13 Formation of the cornified envelope; Neutrophil degranulation Arrhythmogenic right ventricular cardiomyopathy (ARVC) 0 High Q8R1S0 "Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial OS=Mus musculus OX=10090 GN=Coq6 PE=1 SV=3" 0 20.258 13 5 7 5 476 51.4 7.17 5 7 16071035.5 3 metabolic process Golgi;membrane;mitochondrion catalytic activity;nucleotide binding Pf01494 217707 ENSMUSG00000021235.13 Coq6 12 Ubiquinone and other terpenoid-quinone biosynthesis; Metabolic pathways 0 High P62320 Small nuclear ribonucleoprotein Sm D3 OS=Mus musculus OX=10090 GN=Snrpd3 PE=1 SV=1 0 6.048 15 2 7 2 126 13.9 10.32 1 2 2 1 2 2 2 1 2031587.125 11572245.75 29959786 9796343 1 2 2 1 cell organization and biogenesis;metabolic process cytoplasm;cytosol;nucleus;spliceosomal complex protein binding;RNA binding Pf01423 67332 ENSMUSG00000020180.10 Snrpd3 10 mRNA Splicing - Minor Pathway; Cleavage of Growing Transcript in the Termination Region ; mRNA Splicing - Major Pathway; snRNP Assembly; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs; SLBP independent Processing of Histone Pre-mRNAs Spliceosome; Systemic lupus erythematosus 0 High A0A1W2P6G5 Myosin light polypeptide 6 OS=Mus musculus OX=10090 GN=Myl6 PE=1 SV=1 0 10.093 32 3 7 3 139 15.4 4.54 3 1 1 1 4 1 1 1 5792447 2588029.25 2929534.25 5381498.75 3 1 1 2 metal ion binding Pf13499 ENSMUSG00000090841.2 10 0 High Q99KQ4 Nicotinamide phosphoribosyltransferase OS=Mus musculus OX=10090 GN=Nampt PE=1 SV=1 0 14.52 14 4 7 4 491 55.4 7.15 2 1 4 2 1 4 4421065.188 4175098.75 13546799 3 2 3 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;extracellular;nucleus catalytic activity;protein binding Pf04095 59027 ENSMUSG00000020572.8 Nampt 12 "Circadian Clock; Mus musculus biological processes; Nicotinamide salvaging; Bmal1:Clock,Npas2 activates circadian gene expression" NOD-like receptor signaling pathway; Metabolic pathways; Nicotinate and nicotinamide metabolism 0 High P14206 40S ribosomal protein SA OS=Mus musculus OX=10090 GN=Rpsa PE=1 SV=4 0 6.318 13 3 7 3 295 32.8 4.87 3 2 1 3 2 2 3816846.5 8665316.25 12907276 17889012.5 2 2 2 2 cell differentiation;cell organization and biogenesis;metabolic process;transport cytoplasm;cytosol;membrane;nucleus;ribosome protein binding;receptor activity;RNA binding;structural molecule activity Pf00318 16785; 100045332; 102642689 ENSMUSG00000032518.6 Rpsa; LOC100045332; LOC100505031; LOC102642689 9; 19 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High Q8BXX3 GPI-anchor transamidase OS=Mus musculus OX=10090 GN=Pigk PE=1 SV=1 0 23.905 25 6 7 6 364 41 5.54 6 7 7405593.5 1 metabolic process endoplasmic reticulum;membrane catalytic activity Pf01650 329777 ENSMUSG00000039047.17 Pigk 3 0 High Q8VHQ9 Acyl-coenzyme A thioesterase 11 OS=Mus musculus OX=10090 GN=Acot11 PE=1 SV=1 0 16.046 10 5 7 5 594 67.3 6.8 2 1 4 2 1 4 4641106.625 2218760 8114871.375 21143551.25 5 1 4 5 Acetyl [N-Term] metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol catalytic activity "Pf01852, Pf03061, Pf10604" 329910 ENSMUSG00000034853.16 Acot11 4 Mitochondrial Fatty Acid Beta-Oxidation 0 High Q3TUQ5 Pinin OS=Mus musculus OX=10090 GN=Pnn PE=1 SV=1 0 14.676 7 5 7 5 726 82.5 7.01 5 7 5650838.5 8399438.75 2289206.75 2 2 1 metabolic process;regulation of biological process cytoplasm;membrane;nucleus;spliceosomal complex DNA binding;RNA binding "Pf04696, Pf04697" 18949 ENSMUSG00000020994.5 Pnn 12 mRNA surveillance pathway; RNA transport 0 High Q6NZQ4 PAX-interacting protein 1 OS=Mus musculus OX=10090 GN=Paxip1 PE=1 SV=1 0 13.967 8 6 7 6 1056 119.2 7.2 6 1 6 1 3316782.094 466926.5625 489294.3125 5 1 1 cell differentiation;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus chromosome;nucleus protein binding "Pf00533, Pf12738" 55982 ENSMUSG00000002221.11 Paxip1 5 Nonhomologous End-Joining (NHEJ) 0 High Q9WVK4 EH domain-containing protein 1 OS=Mus musculus OX=10090 GN=Ehd1 PE=1 SV=1 0 5.513 3 2 7 1 534 60.6 6.83 1 1 1 2 2 1 1 3 3522843 1 cell organization and biogenesis;regulation of biological process;response to stimulus;transport endosome;membrane metal ion binding;nucleotide binding;protein binding "Pf00350, Pf01926, Pf12763" 13660 ENSMUSG00000024772.9; ENSMUSG00000107039.1 Ehd1 19; CHR_MG4249_PATCH Factors involved in megakaryocyte development and platelet production Endocytosis 0 High Q91YR7 Pre-mRNA-processing factor 6 OS=Mus musculus OX=10090 GN=Prpf6 PE=1 SV=1 0 20.964 9 7 7 7 941 106.7 8.09 1 6 1 6 4287005.375 11975104.25 2274328 2 3 1 cell organization and biogenesis;metabolic process;regulation of biological process membrane;nucleus;spliceosomal complex protein binding;RNA binding "Pf06424, Pf13414, Pf14559" 68879 ENSMUSG00000002455.14 Prpf6 2 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway Spliceosome 0 High P10639 Thioredoxin OS=Mus musculus OX=10090 GN=Txn PE=1 SV=3 0 9.935 32 3 7 3 105 11.7 4.92 2 1 1 1 4 1 1 1 6412090.125 2423655.75 9694035.875 16917072.25 3 1 3 3 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;extracellular;mitochondrion;nucleus antioxidant activity;catalytic activity;protein binding;RNA binding "Pf00085, Pf13098, Pf13899, Pf13905" 22166 ENSMUSG00000028367.5 Txn1 4 Interconversion of nucleotide di- and triphosphates; Protein repair; Detoxification of Reactive Oxygen Species; TP53 Regulates Metabolic Genes; Oxidative Stress Induced Senescence; The NLRP3 inflammasome NOD-like receptor signaling pathway 0 High A0A087WSN5 Phosphatidylinositol-glycan biosynthesis class X protein OS=Mus musculus OX=10090 GN=Pigx PE=1 SV=2 0 28.226 29 5 7 5 252 28.4 6.4 5 7 2137137.75 47621481 1 5 0 High A0A075B674 Immunoglobulin heavy variable 1-78 OS=Mus musculus OX=10090 GN=Ighv1-78 PE=1 SV=1 0 11.735 44 3 7 2 98 11 8.43 2 2 1 4 2 1 4255838.125 3270873.5 4376528.125 1 1 1 "Pf00047, Pf07686" ENSMUSG00000096326.2 12 0 High A0A087WR97 TAR DNA-binding protein 43 (Fragment) OS=Mus musculus OX=10090 GN=Tardbp PE=1 SV=1 0 16.255 26 3 7 3 243 26.7 7.77 3 2 1 4 2 1 4698001.75 7754894.75 5887101 7681758 2 3 2 2 metabolic process;regulation of biological process RNA binding "Pf00076, Pf14259" ENSMUSG00000041459.15 4 0 High Q61656 Probable ATP-dependent RNA helicase DDX5 OS=Mus musculus OX=10090 GN=Ddx5 PE=1 SV=2 0 12.868 8 5 7 5 614 69.2 8.92 3 2 2 3 2 2 5606126.188 2402797.25 8825196.5 12896160.88 5 1 4 4 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus;spliceosomal complex catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00270, Pf00271, Pf08061" 13207 Ddx5 11 0 High P62911 60S ribosomal protein L32 OS=Mus musculus OX=10090 GN=Rpl32 PE=1 SV=2 0 9.424 33 4 7 4 135 15.9 11.33 1 3 1 1 1 4 1 1 1595388.625 11758805.75 10591355.75 14846427 1 2 2 2 metabolic process;response to stimulus membrane;ribosome RNA binding;structural molecule activity Pf01655 19951; 652989 ENSMUSG00000057841.5 Rpl32; Rpl32p 6; X L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q99M28 RNA-binding protein with serine-rich domain 1 OS=Mus musculus OX=10090 GN=Rnps1 PE=1 SV=1 0 9.16 10 3 7 3 305 34.2 11.84 3 2 5 2 294143.2188 8160510.078 20924464.59 10237028.63 1 3 3 3 metabolic process;regulation of biological process cytoplasm;nucleus RNA binding "Pf00076, Pf08777, Pf11608, Pf13893, Pf14259" 19826 ENSMUSG00000034681.16 Rnps1 17 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA surveillance pathway; RNA transport 0 High Q61702 Inter-alpha-trypsin inhibitor heavy chain H1 OS=Mus musculus OX=10090 GN=Itih1 PE=1 SV=2 0 13.258 5 5 7 5 907 101 6.96 5 7 7209316.375 4190507.875 4470339 2296411.5 5 2 2 1 metabolic process;regulation of biological process extracellular enzyme regulator activity "Pf00092, Pf06668, Pf08487, Pf13519, Pf13768" 16424 ENSMUSG00000006529.14 Itih1 14 0 High Q9Z2I0 Mitochondrial proton/calcium exchanger protein OS=Mus musculus OX=10090 GN=Letm1 PE=1 SV=1 0 30.138 15 6 7 6 738 82.9 6.52 6 7 275236.7188 2886583.5 1 1 cell organization and biogenesis;cellular homeostasis;transport membrane;mitochondrion metal ion binding;transporter activity Pf07766 56384 ENSMUSG00000005299.6 Letm1 5 0 High A0A075B5X3 Immunoglobulin heavy variable 1-64 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-64 PE=4 SV=1 0 13.581 42 3 7 1 117 12.9 9.06 2 1 2 1 3 1 2 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000094088.2 12 0 High P00405 Cytochrome c oxidase subunit 2 OS=Mus musculus OX=10090 GN=Mtco2 PE=1 SV=1 0 9.632 16 3 7 3 227 26 4.73 1 2 1 3 1 2 1 3 4028161 14370321 9799986.5 46385843 2 2 2 3 metabolic process;response to stimulus;transport membrane;mitochondrion catalytic activity;metal ion binding;transporter activity "Pf00116, Pf02790" 17709; 3338897 ENSMUSG00000064354.1 COX2 MT Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 High D6RG69 Coiled-coil domain-containing protein 167 OS=Mus musculus OX=10090 GN=Ccdc167 PE=1 SV=1 0 22.357 52 4 7 4 54 6.1 8.16 4 7 2062025.75 57317743.5 2 5 Pf15188 ENSMUSG00000024018.17 17 0 High Q9D172 "Glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrial OS=Mus musculus OX=10090 GN=Gatd3a PE=1 SV=1" 0 13.502 19 4 7 4 266 28.1 8.78 1 1 1 3 2 1 1 3 2557736.5 4579690 3108368.125 9314318.25 1 2 2 2 mitochondrion Pf01965 28295; 102641949 ENSMUSG00000053329.7 D10Jhu81e; LOC100046684; LOC102641949 10 0 High G3UYV7 40S ribosomal protein S28 (Fragment) OS=Mus musculus OX=10090 GN=Rps28 PE=1 SV=1 0 6.52 38 2 7 2 56 6.3 9.96 1 1 2 2 1 2 2 2 4471649.875 8898923.5 12676344 20036211 2 2 2 2 metabolic process ribosome structural molecule activity Pf01200 ENSMUSG00000067288.12 17 0 High Q9D517 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma OS=Mus musculus OX=10090 GN=Agpat3 PE=1 SV=2 0 12.299 14 5 7 5 376 43.3 8.51 5 7 295143.25 32120405 1 4 metabolic process endoplasmic reticulum;membrane;nucleus catalytic activity Pf01553 28169 ENSMUSG00000001211.15 Agpat3 10 Synthesis of PA; COPI-independent Golgi-to-ER retrograde traffic Phospholipase D signaling pathway; Metabolic pathways; Glycerophospholipid metabolism; Glycerolipid metabolism 0 High A0A075B5R2 Immunoglobulin heavy variable 7-3 (Fragment) OS=Mus musculus OX=10090 GN=Ighv7-3 PE=4 SV=2 0 13.388 31 3 7 3 120 13.4 8.6 3 1 1 5 1 1 35118578.38 12362888.75 23405772.75 9364351.75 4 3 2 2 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000076652.4 12 0 High A0A494BBP4 Latent-transforming growth factor beta-binding protein 3 (Fragment) OS=Mus musculus OX=10090 GN=Ltbp3 PE=1 SV=1 0 21.252 23 6 7 1 415 45.8 4.88 6 7 0 High Q91WP0 Mannan-binding lectin serine protease 2 OS=Mus musculus OX=10090 GN=Masp2 PE=1 SV=1 0 14.702 7 4 7 4 685 75.5 6.07 4 7 7492717.375 1417395.375 1916556.5 2256344.5 4 1 1 1 defense response;metabolic process;regulation of biological process;response to stimulus extracellular catalytic activity;metal ion binding;protein binding "Pf00084, Pf00089, Pf00431, Pf07645, Pf12662, Pf14670" 17175 ENSMUSG00000028979.17 Masp2 4 Ficolins bind to repetitive carbohydrate structures on the target cell surface; Lectin pathway of complement activation Staphylococcus aureus infection; Complement and coagulation cascades 0 High Q8VCB3 "Glycogen [starch] synthase, liver OS=Mus musculus OX=10090 GN=Gys2 PE=1 SV=2" 0 7.905 3 3 7 2 704 80.8 6.89 3 1 1 5 1 1 1483826.625 2 metabolic process;response to stimulus cytoplasm;cytoskeleton;cytosol catalytic activity "Pf00534, Pf05693" 232493 ENSMUSG00000030244.7 Gys2 6 Glycogen synthesis Insulin signaling pathway; Metabolic pathways; Insulin resistance; Starch and sucrose metabolism; PI3K-Akt signaling pathway; AMPK signaling pathway; Glucagon signaling pathway 0 Medium F6T4M4 Serine/arginine repetitive matrix protein 1 (Fragment) OS=Mus musculus OX=10090 GN=Srrm1 PE=1 SV=1 0.044 1.033 6 1 7 1 140 16.2 5.38 1 1 1 2 3 2 214785315 175419247 207143292 136192267.3 1 1 1 1 metabolic process Pf01480 ENSMUSG00000028809.16 4 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript 0 High Q8R0X7 Sphingosine-1-phosphate lyase 1 OS=Mus musculus OX=10090 GN=Sgpl1 PE=1 SV=1 0 16.216 10 5 7 5 568 63.6 9.1 1 5 1 6 238042.7813 3033464.813 30924540.5 1 2 4 cell death;cell differentiation;cellular component movement;metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;membrane catalytic activity "Pf00155, Pf00266, Pf00282, Pf01212, Pf05889" 20397 ENSMUSG00000020097.14 Sgpl1 10 Sphingolipid de novo biosynthesis Metabolic pathways; Sphingolipid signaling pathway; Sphingolipid metabolism 0 High P00329 Alcohol dehydrogenase 1 OS=Mus musculus OX=10090 GN=Adh1 PE=1 SV=2 0 9.84 11 5 7 5 375 39.7 8.1 4 3 4 3 4788276.438 3882243.063 1901902.125 20611851.75 4 3 1 5 metabolic process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00107, Pf08240" 11522 ENSMUSG00000074207.10 Adh1 3 RA biosynthesis pathway; Ethanol oxidation; Abacavir metabolism Drug metabolism - cytochrome P450; Retinol metabolism; Metabolic pathways; Fatty acid degradation; Glycolysis / Gluconeogenesis; Chemical carcinogenesis; Tyrosine metabolism; Metabolism of xenobiotics by cytochrome P450 0 High Q80ZS3 "28S ribosomal protein S26, mitochondrial OS=Mus musculus OX=10090 GN=Mrps26 PE=1 SV=1" 0 15.181 25 4 7 4 200 23.4 9.96 2 2 3 2 2 3 3528019.25 3659385 4050293.25 1 1 1 mitochondrion;ribosome RNA binding Pf14943 99045 ENSMUSG00000037740.8 Mrps26 2 Mitochondrial translation termination; Mitochondrial translation elongation 0 High P47758 Signal recognition particle receptor subunit beta OS=Mus musculus OX=10090 GN=Srprb PE=1 SV=1 0 28.859 38 7 7 7 269 29.6 9.28 7 7 regulation of biological process;response to stimulus cytoplasm;endoplasmic reticulum;membrane nucleotide binding;protein binding "Pf00009, Pf00025, Pf01926, Pf09439" 20818 ENSMUSG00000032553.14 Srprb 9 Protein export 0 High P26151 High affinity immunoglobulin gamma Fc receptor I OS=Mus musculus OX=10090 GN=Fcgr1 PE=1 SV=1 0 10.444 9 3 6 3 404 44.9 6.09 3 1 5 1 6786096.5 1255901.375 2008819.25 3261875.25 3 1 1 1 cell organization and biogenesis;defense response;regulation of biological process;response to stimulus;transport membrane protein binding;receptor activity;signal transducer activity "Pf00047, Pf10066, Pf13895, Pf13927" 14129 ENSMUSG00000015947.10 Fcgr1 3 Cross-presentation of soluble exogenous antigens (endosomes); Role of phospholipids in phagocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR activation Staphylococcus aureus infection; Tuberculosis; Osteoclast differentiation; Phagosome; Transcriptional misregulation in cancer; Fc gamma R-mediated phagocytosis; Systemic lupus erythematosus; Leishmaniasis; Hematopoietic cell lineage 0 High E9Q1W3 Nebulin OS=Mus musculus OX=10090 GN=Neb PE=1 SV=1 0 4.001 0 1 6 1 7152 828.1 9.07 1 1 2 4 1579944418 683805853 1411394834 597966623 2 2 3 2 cell organization and biogenesis;regulation of biological process protein binding "Pf00880, Pf14604" 17996 ENSMUSG00000026950.17 Neb 2 Striated Muscle Contraction 0 High P26369 Splicing factor U2AF 65 kDa subunit OS=Mus musculus OX=10090 GN=U2af2 PE=1 SV=3 0 15.004 21 5 6 5 475 53.5 9.09 1 4 1 5 metabolic process;regulation of biological process nucleus;spliceosomal complex protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 22185 ENSMUSG00000030435.16 U2af2 7 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript Spliceosome 0 High Q9D136 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 OS=Mus musculus OX=10090 GN=Ogfod3 PE=2 SV=1 0 14.642 15 4 6 4 315 35.4 6.74 4 6 1391210.25 39002264 1 4 metabolic process membrane catalytic activity;metal ion binding Pf13640 66179 ENSMUSG00000025169.6 1110031I02Rik; Ogfod3 11 0 High Q9JHP7 Protein O-glucosyltransferase 2 OS=Mus musculus OX=10090 GN=Poglut2 PE=1 SV=1 0 23.838 13 5 6 5 502 57.9 7.9 5 6 11918204.25 3 metabolic process endoplasmic reticulum;organelle lumen catalytic activity;protein binding "Pf00630, Pf05686, Pf13524" 72050 ENSMUSG00000026047.13 Kdelc1 1 0 High A0A494B9A7 "Cofilin, non-muscle isoform OS=Mus musculus OX=10090 GN=Cfl1 PE=1 SV=1" 0 10.812 21 4 6 3 178 19.7 8.59 1 4 1 5 1665316.5 4215849.875 23816032 2 2 3 Met-loss+Acetyl [N-Term] 1 High P84099 60S ribosomal protein L19 OS=Mus musculus OX=10090 GN=Rpl19 PE=1 SV=1 0 7.239 17 3 6 3 196 23.5 11.47 2 1 1 2 2 1 1 2 1411975.75 7300721 6709310.5 10612113 1 1 1 1 metabolic process membrane;ribosome RNA binding;structural molecule activity Pf01280 19921; 100041511 ENSMUSG00000017404.12 Rpl19; Rpl19-ps11 11; 8 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q8BPT6 Mitochondrial inner membrane protease subunit 2 OS=Mus musculus OX=10090 GN=Immp2l PE=1 SV=1 0 10.814 17 4 6 4 175 19.6 9.54 4 6 52127444.5 3 cell organization and biogenesis;metabolic process;response to stimulus membrane;mitochondrion catalytic activity "Pf00717, Pf10502" 93757 ENSMUSG00000056899.10 Immp2l 12 Protein export 0 High Q9DCX2 "ATP synthase subunit d, mitochondrial OS=Mus musculus OX=10090 GN=Atp5pd PE=1 SV=3" 0 20.168 48 5 6 5 161 18.7 5.69 1 5 1 5 700910 6569929 1 1 metabolic process;transport cytosol;membrane;mitochondrion catalytic activity;transporter activity Pf05873 71679 ENSMUSG00000034566.10 Atp5h 11 Cristae formation; Formation of ATP by chemiosmotic coupling Metabolic pathways; Huntington's disease; Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High Q8CJG0 Protein argonaute-2 OS=Mus musculus OX=10090 GN=Ago2 PE=1 SV=3 0 13.396 8 5 6 2 860 97.2 9.19 3 1 1 1 3 1 1 1 7234578.5 6264581.625 3396024.125 4894439 3 3 2 1 cell differentiation;cell organization and biogenesis;development;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;DNA binding;metal ion binding;protein binding;RNA binding "Pf02170, Pf02171, Pf08699" 239528 ENSMUSG00000036698.10 Ago2; Eif2c2 15 MicroRNA (miRNA) biogenesis; Transcriptional regulation by small RNAs; Post-transcriptional silencing by small RNAs; Small interfering RNA (siRNA) biogenesis 3 High G3UXT7 RNA-binding protein FUS (Fragment) OS=Mus musculus OX=10090 GN=Fus PE=1 SV=1 0 14.053 36 5 6 5 130 14 8.97 5 6 6377128.5 4956866.25 8348786.5 4 2 2 regulation of biological process cytoplasm;nucleus metal ion binding;RNA binding "Pf00076, Pf00641, Pf13893, Pf14259" ENSMUSG00000030795.18 7 0 High A2AEX6 Four and a half LIM domains protein 1 OS=Mus musculus OX=10090 GN=Fhl1 PE=1 SV=1 0 13.958 20 5 6 5 309 35.1 8.44 5 6 5039698.563 4 cell differentiation;development;regulation of biological process cytoplasm;cytosol;membrane;nucleus metal ion binding;protein binding Pf00412 14199 ENSMUSG00000023092.16 Fhl1 X 0 High Q8VE22 "28S ribosomal protein S23, mitochondrial OS=Mus musculus OX=10090 GN=Mrps23 PE=1 SV=1" 0 11.682 23 3 6 3 177 20.3 8.59 3 2 1 3 2 1 1188268.75 10841618 10368209 9814850.25 2 2 2 2 metabolic process cytoskeleton;membrane;mitochondrion;ribosome RNA binding;structural molecule activity "Pf10484, Pf13741" 64656 ENSMUSG00000023723.17; ENSMUSG00000098375.6 Mrps23 11; CHR_MG3829_PATCH Mitochondrial translation termination; Mitochondrial translation elongation 0 High Q8VDD5 Myosin-9 OS=Mus musculus OX=10090 GN=Myh9 PE=1 SV=4 0 15.909 3 5 6 5 1960 226.2 5.66 5 1 5 1 3997016.531 5 cell differentiation;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;cytosol;extracellular;membrane;nucleus catalytic activity;motor activity;nucleotide binding;protein binding;RNA binding;transporter activity "Pf00063, Pf01442, Pf01496, Pf01576, Pf01765, Pf02463, Pf02736, Pf03962, Pf04111, Pf04156, Pf05667, Pf05911, Pf06160, Pf06637, Pf07111, Pf07888, Pf08317, Pf09726, Pf09731, Pf10498, Pf11559, Pf11917, Pf12128, Pf13094, Pf13166" 17886 ENSMUSG00000022443.16 Myh9 15 RHO GTPases activate PAKs Regulation of actin cytoskeleton; Tight junction 0 High Q8CJG1 Protein argonaute-1 OS=Mus musculus OX=10090 GN=Ago1 PE=1 SV=2 0 11.93 8 5 6 2 857 97.2 9.16 4 1 1 4 1 1 470486.5938 1 Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;nucleus DNA binding;protein binding;RNA binding "Pf02170, Pf02171, Pf08699" 236511 ENSMUSG00000041530.16 Ago1; Eif2c1 4 Transcriptional regulation by small RNAs; Post-transcriptional silencing by small RNAs 0 High Q9JJL8 "Serine--tRNA ligase, mitochondrial OS=Mus musculus OX=10090 GN=Sars2 PE=1 SV=2" 0 15.763 11 3 6 3 518 58.3 7.9 1 3 2 4 314184.6875 5610236 7669416.75 1 2 2 metabolic process cytoplasm;mitochondrion;organelle lumen catalytic activity;nucleotide binding;RNA binding Pf00587 71984 ENSMUSG00000070699.5 Sars2 7 Aminoacyl-tRNA biosynthesis 0 High Q8VCD5 Mediator of RNA polymerase II transcription subunit 17 OS=Mus musculus OX=10090 GN=Med17 PE=1 SV=1 0 13.211 12 6 6 6 649 72.4 7.3 4 1 1 4 1 1 3466296.789 1784310.219 147995.9375 5 2 1 metabolic process;regulation of biological process;response to stimulus membrane;nucleus catalytic activity;protein binding;receptor activity Pf10156 234959 ENSMUSG00000031935.9 Med17 9 Generic Transcription Pathway; Mus musculus biological processes; Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes Thyroid hormone signaling pathway 0 High A0A1W2P7J1 Coenzyme Q10A OS=Mus musculus OX=10090 GN=Coq10a PE=1 SV=1 0 15.603 24 5 6 5 249 27.9 9.99 5 6 406098.4063 5264601.5 1 1 metabolic process mitochondrion Pf03364 210582 ENSMUSG00000039914.6 Coq10a 10 0 High Q62376 U1 small nuclear ribonucleoprotein 70 kDa OS=Mus musculus OX=10090 GN=Snrnp70 PE=1 SV=2 0 8.918 9 4 6 4 448 52 9.94 1 1 4 1 1 4 656964.375 2011406.375 7065104.5 4465984.875 1 1 2 2 metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus;spliceosomal complex RNA binding "Pf00076, Pf12220, Pf13893, Pf14259" 20637 ENSMUSG00000063511.11 Snrnp70 7 mRNA Splicing - Major Pathway Spliceosome 0 High P08121 Collagen alpha-1(III) chain OS=Mus musculus OX=10090 GN=Col3a1 PE=1 SV=4 0 23.805 5 5 6 5 1464 138.9 6.52 4 1 5 1 5734723.625 1787586.75 2642137.5 2 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus extracellular metal ion binding;protein binding;structural molecule activity "Pf00093, Pf01391, Pf01410, Pf14828" 12825 ENSMUSG00000026043.18 Col3a1 1 ECM proteoglycans; Collagen chain trimerization; Integrin cell surface interactions; MET activates PTK2 signaling; NCAM1 interactions; Collagen degradation; Non-integrin membrane-ECM interactions; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; Signaling by PDGF; Assembly of collagen fibrils and other multimeric structures AGE-RAGE signaling pathway in diabetic complications; Protein digestion and absorption; Platelet activation; Amoebiasis 0 High A0A494B9H1 Nucleotide exchange factor SIL1 OS=Mus musculus OX=10090 GN=Sil1 PE=1 SV=1 0 25.899 18 4 6 4 417 46.8 6 4 6 0 High P70349 Histidine triad nucleotide-binding protein 1 OS=Mus musculus OX=10090 GN=Hint1 PE=1 SV=3 0 15.995 30 2 6 2 126 13.8 6.87 2 1 5 1 7956091 1785370 2 1 cell death;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;nucleus catalytic activity;nucleotide binding "Pf01230, Pf11969" 15254 ENSMUSG00000020267.6 Hint1 11 0 High P63030 Mitochondrial pyruvate carrier 1 OS=Mus musculus OX=10090 GN=Mpc1 PE=1 SV=1 0 12.2 39 4 6 4 109 12.4 9.61 1 4 1 5 590997.0625 1409860.125 4745689.5 62848408 1 1 1 3 metabolic process;transport membrane;mitochondrion catalytic activity;transporter activity "Pf01483, Pf03650" 55951 ENSMUSG00000023861.17 Mpc1 17 0 High A0A0R3P9C8 "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial OS=Mus musculus OX=10090 GN=Ndufa9 PE=1 SV=1" 0 15.859 18 6 6 6 373 42.1 9.09 1 5 1 5 1650991.75 311173.375 20816971 3 1 5 metabolic process membrane;mitochondrion catalytic activity "Pf01073, Pf01370, Pf05368, Pf13460" ENSMUSG00000000399.10 6 0 High P50543 Protein S100-A11 OS=Mus musculus OX=10090 GN=S100a11 PE=1 SV=1 0 20.907 74 4 6 4 98 11.1 5.45 4 6 1086668.875 1855330.5 16239575.5 1 1 3 regulation of biological process cytoplasm;extracellular;nucleus metal ion binding;protein binding "Pf00036, Pf01023, Pf13499, Pf13833" 20195 ENSMUSG00000027907.4 S100a11 3 Neutrophil degranulation 0 High P80315 T-complex protein 1 subunit delta OS=Mus musculus OX=10090 GN=Cct4 PE=1 SV=3 0 11.952 12 4 6 4 539 58 8.02 3 1 1 3 2 1 2344509.375 460005.9375 1231995 2763055.75 4 1 1 1 metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;cytosol nucleotide binding;protein binding;RNA binding Pf00118 12464 ENSMUSG00000007739.10 Cct4 11 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Association of TriC/CCT with target proteins during biosynthesis 0 High P62983 Ubiquitin-40S ribosomal protein S27a OS=Mus musculus OX=10090 GN=Rps27a PE=1 SV=2 0 10.433 16 2 6 2 156 17.9 9.64 1 1 2 2 1 1 2 2 963082.625 4402542.5 4094673.5 5873133.5 1 1 1 1 metabolic process cytoplasm;cytosol;membrane;nucleus;ribosome metal ion binding;protein binding;RNA binding;structural molecule activity "Pf00240, Pf01599, Pf11976, Pf13019, Pf13881, Pf14560" 78294; 619900; 100042019 ENSMUSG00000020460.15 Rps27a; Rps27a-ps2; LOC100042019 11; 9 "Termination of translesion DNA synthesis; PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1; NOD1/2 Signaling Pathway; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Ovarian tumor domain proteases; UCH proteinases; Stimuli-sensing channels; p75NTR recruits signalling complexes; Josephin domain DUBs; Spry regulation of FGF signaling; SRP-dependent cotranslational protein targeting to membrane; Ub-specific processing proteases; IKK complex recruitment mediated by RIP1; IRAK2 mediated activation of TAK1 complex; Activation of NF-kappaB in B cells; EGFR downregulation; Regulation of necroptotic cell death; Regulation of signaling by CBL; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Formation of a pool of free 40S subunits; Regulation of TP53 Degradation; Regulation of TP53 Activity through Phosphorylation; NF-kB is activated and signals survival; Downstream TCR signaling; Association of licensing factors with the pre-replicative complex; Autodegradation of Cdh1 by Cdh1:APC/C; TRAF6-mediated induction of TAK1 complex within TLR4 complex; Asymmetric localization of PCP proteins; Interleukin-1 family signaling; TNFR1-induced NFkappaB signaling pathway; G2/M Checkpoints; Regulation of PTEN localization; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Mus musculus biological processes; Regulation of PTEN stability and activity; APC-Cdc20 mediated degradation of Nek2A; Formation of the ternary complex, and subsequently, the 43S complex; Regulation of TP53 Activity through Methylation; E3 ubiquitin ligases ubiquitinate target proteins; Translesion synthesis by POLI; Interleukin-20 family signaling; Downregulation of ERBB4 signaling; Dual Incision in GG-NER; ER Quality Control Compartment (ERQC); Neddylation; Negative regulators of DDX58/IFIH1 signaling; Gap-filling DNA repair synthesis and ligation in TC-NER; APC/C:Cdc20 mediated degradation of Securin; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Antigen processing: Ubiquitination & Proteasome degradation; Translesion Synthesis by POLH; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; TAK1 activates NFkB by phosphorylation and activation of IKKs complex; Oxidative Stress Induced Senescence; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Regulation of PLK1 Activity at G2/M Transition; Senescence-Associated Secretory Phenotype (SASP); Oncogene Induced Senescence; Formation of TC-NER Pre-Incision Complex; AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of expression of SLITs and ROBOs; APC/C:Cdc20 mediated degradation of Cyclin B; Translation initiation complex formation; Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon; Regulation of FZD by ubiquitination; Recognition of DNA damage by PCNA-containing replication complex; Translesion synthesis by REV1; Circadian Clock; Degradation of DVL; Degradation of AXIN; The role of GTSE1 in G2/M progression after G2 checkpoint; CDT1 association with the CDC6:ORC:origin complex; Endosomal Sorting Complex Required For Transport (ESCRT); Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Degradation of beta-catenin by the destruction complex; NRIF signals cell death from the nucleus; Autodegradation of the E3 ubiquitin ligase COP1; MAPK6/MAPK4 signaling; SCF-beta-TrCP mediated degradation of Emi1; CDK-mediated phosphorylation and removal of Cdc6; Separation of Sister Chromatids; SCF(Skp2)-mediated degradation of p27/p21; Regulation of innate immune responses to cytosolic DNA; GLI3 is processed to GLI3R by the proteasome; Translesion synthesis by POLK; Activated TLR4 signalling; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); DNA Damage Recognition in GG-NER; Degradation of GLI1 by the proteasome; FCERI mediated NF-kB activation; Formation of Incision Complex in GG-NER; Gap-filling DNA repair synthesis and ligation in GG-NER; Hedgehog ligand biogenesis; Regulation of RAS by GAPs; Activated NOTCH1 Transmits Signal to the Nucleus; Cyclin D associated events in G1; Dual incision in TC-NER; Negative regulation of MAPK pathway; Pink/Parkin Mediated Mitophagy; Cargo recognition for clathrin-mediated endocytosis; Ubiquitin-dependent degradation of Cyclin D1; Metalloprotease DUBs; MAP3K8 (TPL2)-dependent MAPK1/3 activation; NIK-->noncanonical NF-kB signaling; Removal of licensing factors from origins; IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation; M/G1 Transition; Negative regulation of MET activity; L13a-mediated translational silencing of Ceruloplasmin expression; Downregulation of ERBB2:ERBB3 signaling; activated TAK1 mediates p38 MAPK activation; Regulation of RUNX2 expression and activity; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ABC-family proteins mediated transport; Regulation of DNA replication; Glycogen synthesis; Dectin-1 mediated noncanonical NF-kB signaling; Downregulation of SMAD2/3:SMAD4 transcriptional activity; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Orc1 removal from chromatin; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition); Regulation of TNFR1 signaling; Regulation of RUNX3 expression and activity; Hedgehog 'on' state; Fanconi Anemia Pathway; HDR through Homologous Recombination (HRR); Iron uptake and transport; JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Signalling by NGF; Downregulation of TGF-beta receptor signaling" Ribosome 0 High P62889 60S ribosomal protein L30 OS=Mus musculus OX=10090 GN=Rpl30 PE=1 SV=2 0 14.832 37 3 6 3 115 12.8 9.63 1 1 1 3 1 1 1 3 3905749.813 7500427.375 11025598.25 12490010.25 2 2 2 2 defense response;metabolic process;response to stimulus membrane;nucleus;ribosome RNA binding;structural molecule activity Pf01248 19946; 667779; 666899 ENSMUSG00000058600.13 Rpl30; Rpl30-ps8; Gm12191 15; 12; 11 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q3TFP0 Serine/arginine-rich-splicing factor 10 OS=Mus musculus OX=10090 GN=Srsf10 PE=1 SV=1 0 8.088 21 3 6 3 182 22.1 10.33 1 2 2 1 2 3 659192.875 3646032.313 4606852.5 1642141.375 1 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;transport cytosol;nucleus protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 14105 ENSMUSG00000028676.17 Srsf10 4 0 High Q6ZWU9 40S ribosomal protein S27 OS=Mus musculus OX=10090 GN=Rps27 PE=1 SV=3 0 12.533 39 4 6 1 84 9.5 9.45 1 4 1 5 6244009.594 3954422 8537399.5 66535037 3 1 2 3 cell organization and biogenesis;metabolic process ribosome metal ion binding;protein binding;structural molecule activity Pf01667 57294; 100043813 ENSMUSG00000090733.6; ENSMUSG00000050621.7 Rps27; Gm9846; Rps27rt 3; 9 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Formation of a pool of free 40S subunits; Translation initiation complex formation; L13a-mediated translational silencing of Ceruloplasmin expression; Resolution of Sister Chromatid Cohesion; Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal; Separation of Sister Chromatids; Ribosomal scanning and start codon recognition; RHO GTPases Activate Formins; GTP hydrolysis and joining of the 60S ribosomal subunit; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex" Ribosome 3 High P20108 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Mus musculus OX=10090 GN=Prdx3 PE=1 SV=1" 0 12.43 22 5 6 5 257 28.1 7.58 4 1 1 4 1 1 6686595.688 2638975.25 7172559.75 3633839 5 1 3 1 cell death;cell differentiation;cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;endosome;mitochondrion antioxidant activity;catalytic activity;enzyme regulator activity;protein binding "Pf00578, Pf08534, Pf10417, Pf13905" 11757 ENSMUSG00000024997.7 Prdx3 19 Detoxification of Reactive Oxygen Species 0 High A0A075B5W2 Immunoglobulin heavy variable 1-52 OS=Mus musculus OX=10090 GN=Ighv1-52 PE=4 SV=1 0 9.906 21 2 6 1 116 13 7.88 2 1 1 1 3 1 1 1 Pf07686 ENSMUSG00000095204.6 12 0 High P50428 Arylsulfatase A OS=Mus musculus OX=10090 GN=Arsa PE=1 SV=2 0 18.526 19 5 6 5 506 53.7 5.87 5 6 323557.3125 19819250 1 2 metabolic process;response to stimulus cytoplasm;endosome;membrane;vacuole catalytic activity;metal ion binding "Pf00884, Pf07394, Pf14707" 11883 ENSMUSG00000022620.14 Arsa 15 Neutrophil degranulation; Glycosphingolipid metabolism; The activation of arylsulfatases Lysosome; Sphingolipid metabolism 0 High Q6PE01 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Mus musculus OX=10090 GN=Snrnp40 PE=1 SV=1 0 20.827 15 3 6 3 358 39.3 8.1 2 2 3 3 11377145.88 18348814.5 1863047.125 3 3 1 metabolic process cytosol;nucleus;spliceosomal complex protein binding;RNA binding Pf00400 66585 ENSMUSG00000074088.6; ENSMUSG00000106911.1 Snrnp40 4; CHR_MG4265_PATCH mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway Spliceosome 0 High P01671 Ig kappa chain V-III region PC 7175 OS=Mus musculus OX=10090 PE=1 SV=1 0 18.691 41 3 6 1 111 12 7.37 3 1 4 2 2227305.5 2889672 1 1 "Pf00047, Pf07679, Pf07686" 0 High A0A1B0GQZ3 Stromal interaction molecule 1 (Fragment) OS=Mus musculus OX=10090 GN=Stim1 PE=1 SV=1 0 19.565 29 4 6 1 207 23.6 6.54 4 6 4521381 1 regulation of biological process ENSMUSG00000030987.5 7 0 High Q99LR1 Lysophosphatidylserine lipase ABHD12 OS=Mus musculus OX=10090 GN=Abhd12 PE=1 SV=2 0 18.278 19 6 6 6 398 45.2 8.72 6 6 142986.4531 7630816.125 1 2 metabolic process;response to stimulus cytoplasm;membrane;mitochondrion catalytic activity "Pf00326, Pf00561, Pf12146, Pf12695, Pf12697" 76192 ENSMUSG00000032046.15 Abhd12 2 Gastrin-CREB signalling pathway via PKC and MAPK; Arachidonate production from DAG 0 High Q61292 Laminin subunit beta-2 OS=Mus musculus OX=10090 GN=Lamb2 PE=1 SV=2 0 17.331 4 5 6 5 1799 196.5 6.67 5 6 3667937.563 4 cell differentiation;cell growth;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;transport cytoplasm;extracellular protein binding "Pf00053, Pf00055, Pf00769, Pf01442, Pf04012, Pf06008, Pf07111, Pf11740, Pf12128, Pf13514, Pf14662, Pf15558" 16779 ENSMUSG00000052911.9 Lamb2 9 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); MET activates PTK2 signaling; Laminin interactions; Post-translational protein phosphorylation Focal adhesion; Toxoplasmosis; Small cell lung cancer; Pathways in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway; Amoebiasis 0 High Q8C7E9 Cleavage stimulation factor subunit 2 tau variant OS=Mus musculus OX=10090 GN=Cstf2t PE=1 SV=2 0 12.625 8 2 6 1 632 65.8 7.25 1 1 2 1 2 3 metabolic process nucleus RNA binding "Pf00076, Pf13893, Pf14259, Pf14304, Pf14327" 83410 ENSMUSG00000053536.6 Cstf2t 19 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Processing of Intronless Pre-mRNAs; Cleavage of Growing Transcript in the Termination Region mRNA surveillance pathway 0 High Q9QUK9 TESP4 OS=Mus musculus OX=10090 GN=Try5 PE=1 SV=1 0 6.105 8 1 6 1 246 26.3 5.3 1 1 1 1 2 1 1 2 3756527.75 9699878 1 1 metabolic process catalytic activity;metal ion binding Pf00089 103964 ENSMUSG00000036938.17 Try5 6 "Cobalamin (Cbl, vitamin B12) transport and metabolism; Neutrophil degranulation; Collagen degradation; Antimicrobial peptides; Activation of Matrix Metalloproteinases" Pancreatic secretion; Protein digestion and absorption; Influenza A; Neuroactive ligand-receptor interaction 0 High Q6ZWY3 40S ribosomal protein S27-like OS=Mus musculus OX=10090 GN=Rps27l PE=1 SV=3 0 12.071 39 4 6 1 84 9.5 9.45 1 4 1 5 1534045.875 2527895.5 10274989 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus nucleus;ribosome enzyme regulator activity;metal ion binding;RNA binding;structural molecule activity;translation regulator activity Pf01667 67941 ENSMUSG00000036781.13 Rps27l 9 0 High O08756 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Mus musculus OX=10090 GN=Hsd17b10 PE=1 SV=4 0 18.69 32 5 6 5 261 27.4 8.41 3 1 2 3 1 2 3157638.25 1778515.5 1920772.375 8452707 3 1 1 2 cell organization and biogenesis;metabolic process endoplasmic reticulum;membrane;mitochondrion catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00106, Pf08659, Pf13561" 15108 Hsd17b10 X 0 High D3YWI1 Fructose-bisphosphate aldolase (Fragment) OS=Mus musculus OX=10090 GN=Aldoa PE=1 SV=8 0 13.11 20 4 6 4 236 25.8 7.14 1 4 2 4 3438715.813 6544072.25 1970848.875 15396656.75 3 3 1 3 metabolic process catalytic activity Pf00274 ENSMUSG00000030695.14 7 0 High P29341 Polyadenylate-binding protein 1 OS=Mus musculus OX=10090 GN=Pabpc1 PE=1 SV=2 0 13.316 10 6 6 6 636 70.6 9.5 6 6 5455735.313 1588566.375 2838536 3930088.875 6 1 2 2 metabolic process;regulation of biological process cytoplasm;cytosol;membrane;nucleus;spliceosomal complex protein binding;RNA binding "Pf00076, Pf00658, Pf13893, Pf14259" 18458 ENSMUSG00000022283.14 Pabpc1 15 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); AUF1 (hnRNP D0) binds and destabilizes mRNA; Translation initiation complex formation; Deadenylation of mRNA mRNA surveillance pathway; RNA degradation; RNA transport 0 High P70451 Tyrosine-protein kinase Fer OS=Mus musculus OX=10090 GN=Fer PE=1 SV=2 0 12.953 4 2 6 2 823 94.5 7.05 2 2 3 3 12705403.75 7533685.75 13333389.75 2 2 3 cell communication;cell organization and biogenesis;cell proliferation;cellular component movement;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;nucleus catalytic activity;nucleotide binding;protein binding "Pf00017, Pf00069, Pf00611, Pf07714" 14158 ENSMUSG00000000127.14 Fert2; Fer 17 Signaling by SCF-KIT Adherens junction 0 High P51175 Protoporphyrinogen oxidase OS=Mus musculus OX=10090 GN=Ppox PE=1 SV=1 0 10.419 10 4 6 4 477 50.8 8.84 3 1 2 3 1 2 5581729.25 4019538 1711032 15856050 4 1 1 4 metabolic process;response to stimulus membrane;mitochondrion catalytic activity "Pf01266, Pf01593, Pf13450" 19044 ENSMUSG00000062729.11 Ppox 1 Heme biosynthesis Metabolic pathways; Porphyrin and chlorophyll metabolism 0 High P19157 Glutathione S-transferase P 1 OS=Mus musculus OX=10090 GN=Gstp1 PE=1 SV=2 0 10.751 27 4 6 4 210 23.6 7.87 4 1 5 1 5573814.875 3841305.25 3 2 cell communication;cell proliferation;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus antioxidant activity;catalytic activity;enzyme regulator activity;protein binding "Pf00043, Pf02798" 14870 ENSMUSG00000060803.5; ENSMUSG00000097830.3 Gstp1 19; CHR_MG153_PATCH Glutathione conjugation; Neutrophil degranulation; Detoxification of Reactive Oxygen Species Glutathione metabolism; Platinum drug resistance; Drug metabolism - cytochrome P450; Chemical carcinogenesis; Metabolism of xenobiotics by cytochrome P450; Prostate cancer 0 High Q8VFG4 Olfactory receptor OS=Mus musculus OX=10090 GN=Olfr1370 PE=2 SV=1 0.007 2.001 3 1 6 1 316 35.3 8.9 1 1 1 1 1 1 2 2 212863284.3 336601068.5 328664076 406766854.5 2 2 2 2 Met-loss [N-Term] regulation of biological process;response to stimulus membrane receptor activity;signal transducer activity "Pf00001, Pf13853" 258528 ENSMUSG00000042869.2 Olfr1370 13 Olfactory transduction 0 High F6RYG0 All-trans retinoic acid-induced differentiation factor (Fragment) OS=Mus musculus OX=10090 GN=Atraid PE=1 SV=1 0 15.588 31 5 6 5 183 19.7 5.1 5 6 258906.4531 184050255.1 1 5 ENSMUSG00000013622.15 5 0 High Q8BJZ4 "28S ribosomal protein S35, mitochondrial OS=Mus musculus OX=10090 GN=Mrps35 PE=1 SV=2" 0 6.898 11 3 6 3 320 36 8.59 3 3 3 3 687070.7813 7324488 5724969.5 12691103 2 2 2 2 mitochondrion;ribosome RNA binding;structural molecule activity Pf10213 232536 Mrps35 6 0 High Q8BIQ5 Cleavage stimulation factor subunit 2 OS=Mus musculus OX=10090 GN=Cstf2 PE=1 SV=2 0 9.278 6 2 6 1 580 61.3 6.83 1 2 1 1 3 2 237615.6875 183132.9375 3956045.375 3351400.25 1 1 2 2 metabolic process;response to stimulus nucleus RNA binding "Pf00076, Pf13893, Pf14259, Pf14304, Pf14327" 108062 ENSMUSG00000031256.11 Cstf2 X mRNA Splicing - Major Pathway; mRNA 3'-end processing; Processing of Intronless Pre-mRNAs; Cleavage of Growing Transcript in the Termination Region mRNA surveillance pathway 1 High P47857 "ATP-dependent 6-phosphofructokinase, muscle type OS=Mus musculus OX=10090 GN=Pfkm PE=1 SV=3" 0 10.786 5 4 6 1 780 85.2 8 1 3 1 5 444610.875 2837626.5 1 1 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process cytoplasm;cytosol;membrane;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding Pf00365 18642 ENSMUSG00000033065.13 Pfkm 15 Glycolysis RNA degradation; Metabolic pathways; Biosynthesis of amino acids; Glycolysis / Gluconeogenesis; Pentose phosphate pathway; AMPK signaling pathway; Carbon metabolism; Fructose and mannose metabolism; Galactose metabolism; Central carbon metabolism in cancer 0 High Q8BFZ9 Erlin-2 OS=Mus musculus OX=10090 GN=Erlin2 PE=1 SV=1 0 15.159 16 5 6 5 340 37.8 5.5 5 6 416881.25 20790472.25 2 3 metabolic process;regulation of biological process;response to stimulus cytosol;endoplasmic reticulum;membrane protein binding Pf01145 244373 ENSMUSG00000031483.8 Erlin2 8 ABC-family proteins mediated transport 0 High A2ABV5 Mediator of RNA polymerase II transcription subunit 14 OS=Mus musculus OX=10090 GN=Med14 PE=1 SV=1 0 13.926 3 4 6 4 1459 160.9 8.53 3 1 1 3 2 1 2171640.133 968634.3125 4 1 metabolic process;regulation of biological process;response to stimulus membrane;nucleus receptor activity "Pf08638, Pf15449" 26896 ENSMUSG00000064127.13 Med14 X Generic Transcription Pathway; Mus musculus biological processes; Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes Thyroid hormone signaling pathway 0 High Q9DCA2 "28S ribosomal protein S11, mitochondrial OS=Mus musculus OX=10090 GN=Mrps11 PE=1 SV=2" 0 6.862 14 2 6 2 191 20.2 10.77 1 2 1 2 1 2 1 2 223958.3906 3591552.75 4685397.5 5605403.5 1 1 1 1 cell organization and biogenesis;metabolic process mitochondrion;ribosome RNA binding;structural molecule activity Pf00411 67994 Mrps11 7 0 High Q3UVD5 Leucine-rich repeat-containing G-protein coupled receptor 6 OS=Mus musculus OX=10090 GN=Lgr6 PE=2 SV=1 0 18.835 8 5 5 5 967 104.2 6.07 5 5 6632784.5 1 regulation of biological process;response to stimulus membrane protein binding;receptor activity;signal transducer activity "Pf12799, Pf13306, Pf13855" 329252 ENSMUSG00000042793.13 Lgr6 1 Regulation of FZD by ubiquitination 0 High Q8BSF4 "Phosphatidylserine decarboxylase proenzyme, mitochondrial OS=Mus musculus OX=10090 GN=Pisd PE=2 SV=1" 0 10.003 10 4 5 4 406 45.9 9.57 4 5 344792.25 999968.5625 1396981.125 24456717 1 1 1 3 metabolic process membrane;mitochondrion;nucleus catalytic activity Pf02666 320951 ENSMUSG00000023452.18 Pisd 5 Metabolic pathways; Glycerophospholipid metabolism 0 High P52825 "Carnitine O-palmitoyltransferase 2, mitochondrial OS=Mus musculus OX=10090 GN=Cpt2 PE=1 SV=2" 0 12.418 8 5 5 5 658 73.9 8.37 5 5 385910.8438 1387577.75 3283576.25 1 1 1 metabolic process;transport membrane;mitochondrion catalytic activity Pf00755 12896 ENSMUSG00000028607.16 Cpt2 4 Import of palmitoyl-CoA into the mitochondrial matrix PPAR signaling pathway; Fatty acid metabolism; Fatty acid degradation 0 High A0A075B5S1 Immunoglobulin heavy variable 9-1 OS=Mus musculus OX=10090 GN=Ighv9-1 PE=4 SV=1 0 4.927 22 2 5 1 98 11.1 7.94 2 1 1 1 2 1 1 1 1102690.125 1 "Pf00047, Pf07686" ENSMUSG00000096805.2 12 0 High Q924T2 "28S ribosomal protein S2, mitochondrial OS=Mus musculus OX=10090 GN=Mrps2 PE=1 SV=1" 0 13.83 20 3 5 3 291 32.3 9.14 1 2 2 1 2 2 876299.1875 3816020 6292199 1 1 2 cell organization and biogenesis;metabolic process mitochondrion;ribosome structural molecule activity Pf00318 118451 ENSMUSG00000035772.11 Mrps2 2 Mitochondrial translation termination; Mitochondrial translation elongation Ribosome 0 High Q9D0L4 AarF domain-containing protein kinase 1 OS=Mus musculus OX=10090 GN=Adck1 PE=1 SV=1 0 22.354 10 4 5 4 525 59.7 8.05 4 5 10005557.75 2 metabolic process extracellular;mitochondrion catalytic activity;enzyme regulator activity;nucleotide binding;receptor activity;signal transducer activity Pf03109 72113 ENSMUSG00000021044.14 Adck1 12 0 High G5E8T6 Membrane-associated guanylate kinase inverted 3 OS=Mus musculus OX=10090 GN=Magi3 PE=1 SV=1 0 9.092 4 4 5 4 1476 161.5 8.05 1 3 1 1 3 1 761510.8125 6140938.875 9764323.75 9588997 1 3 3 3 metabolic process;regulation of biological process;response to stimulus membrane;nucleus catalytic activity;nucleotide binding;protein binding;structural molecule activity "Pf00397, Pf00595, Pf00625, Pf04094, Pf13180" 99470 ENSMUSG00000052539.15 Magi3 3 0 High P61164 Alpha-centractin OS=Mus musculus OX=10090 GN=Actr1a PE=1 SV=1 0 14.746 18 5 5 5 376 42.6 6.64 5 5 812704.25 1218030 13466810 1 1 1 cytoplasm;cytoskeleton nucleotide binding Pf00022 54130 ENSMUSG00000025228.4 Actr1a 19 Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; COPI-mediated anterograde transport; Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes; HSP90 chaperone cycle for steroid hormone receptors (SHR); COPI-independent Golgi-to-ER retrograde traffic; MHC class II antigen presentation 0 High Q9DBL7 Bifunctional coenzyme A synthase OS=Mus musculus OX=10090 GN=Coasy PE=1 SV=2 0 17.466 11 5 5 5 563 62 7.11 5 5 153867.4531 20022264.5 1 3 metabolic process cytoplasm;mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf01121, Pf01467, Pf13207, Pf13238, Pf13671" 71743 ENSMUSG00000001755.12 Coasy 11 Coenzyme A biosynthesis Metabolic pathways; Pantothenate and CoA biosynthesis 0 High Q8BPB5 EGF-containing fibulin-like extracellular matrix protein 1 OS=Mus musculus OX=10090 GN=Efemp1 PE=1 SV=1 0 31.545 17 4 5 4 493 54.9 5.14 4 5 metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;extracellular;membrane catalytic activity;metal ion binding;protein binding;receptor activity;signal transducer activity "Pf06247, Pf07645, Pf12662, Pf12947, Pf14670" 216616 ENSMUSG00000020467.15 Efemp1 11 Molecules associated with elastic fibres 0 High P24549 Retinal dehydrogenase 1 OS=Mus musculus OX=10090 GN=Aldh1a1 PE=1 SV=5 0 4.211 4 2 5 1 501 54.4 7.8 2 1 1 3 1 1 555993 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;nucleus catalytic activity;nucleotide binding;protein binding "Pf00171, Pf05893, Pf07368" 11668 ENSMUSG00000053279.6 Aldh1a1 19 RA biosynthesis pathway; Ethanol oxidation; Fructose catabolism Retinol metabolism; Metabolic pathways 0 High E9Q616 AHNAK nucleoprotein (desmoyokin) OS=Mus musculus OX=10090 GN=Ahnak PE=1 SV=1 0 9.453 6 4 5 4 5656 603.9 6.3 3 1 4 1 1442895.938 1560479.375 2201362.5 3225425.25 3 1 1 1 cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton;cytosol;membrane;nucleus protein binding;RNA binding;structural molecule activity 66395 ENSMUSG00000069833.12 Ahnak 19 0 High Q91VM9 "Inorganic pyrophosphatase 2, mitochondrial OS=Mus musculus OX=10090 GN=Ppa2 PE=1 SV=1" 0 8.306 11 2 5 2 330 38.1 6.98 2 1 4 1 2754108.188 1594632.5 1265194.75 2 1 1 metabolic process cytoplasm;mitochondrion catalytic activity;metal ion binding Pf00719 74776 ENSMUSG00000028013.16 Ppa2 3 Mitochondrial tRNA aminoacylation; Pyrophosphate hydrolysis Oxidative phosphorylation 0 High Q9WTZ2 Membrane-bound transcription factor site-1 protease OS=Mus musculus OX=10090 GN=Mbtps1 PE=1 SV=1 0 15.082 6 4 5 4 1052 117.4 8.76 4 5 cell organization and biogenesis;metabolic process;regulation of biological process endoplasmic reticulum;Golgi;membrane;organelle lumen catalytic activity "Pf00082, Pf14258" 56453 ENSMUSG00000031835.16 Mbtps1 8 CREB3 factors activate genes; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Regulation of cholesterol biosynthesis by SREBP (SREBF); ATF6 (ATF6-alpha) activates chaperones Protein processing in endoplasmic reticulum 0 High Q6PKB0 Fcgrt protein OS=Mus musculus OX=10090 GN=Fcgrt PE=1 SV=1 0 9.103 19 5 5 5 369 40.5 5.54 5 5 19416330.25 4 membrane protein binding;receptor activity;signal transducer activity "Pf00129, Pf07654" 14132 ENSMUSG00000003420.8 Fcgrt 7 0 High A0A1Y7VJH3 Apoptosis-stimulating of p53 protein 1 (Fragment) OS=Mus musculus OX=10090 GN=Ppp1r13b PE=1 SV=1 0 17.377 6 3 5 3 964 104.4 7.23 1 2 2 1 2 2 787405.6875 3142193.25 4500827 1 1 1 cell death;regulation of biological process;response to stimulus protein binding "Pf00018, Pf00023, Pf02463, Pf07653, Pf10498, Pf11711, Pf12795, Pf12796, Pf13606, Pf13637, Pf13857, Pf13863, Pf14604, Pf15324" 0 High Q8CJF9 Protein argonaute-3 OS=Mus musculus OX=10090 GN=Ago3 PE=2 SV=2 0 14.15 7 4 5 2 860 97.2 9.1 4 1 4 1 1055476.219 689642.0625 2 1 Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus chromosome;cytoplasm;membrane protein binding;RNA binding "Pf02170, Pf02171, Pf08699" 214150 ENSMUSG00000028842.15 Ago3; Eif2c3 4 Post-transcriptional silencing by small RNAs 0 High P70168 Importin subunit beta-1 OS=Mus musculus OX=10090 GN=Kpnb1 PE=1 SV=2 0 5.167 2 2 5 2 876 97.1 4.78 2 1 1 1 2 1 1 1 230067.875 268216.0625 590070 889948.3125 2 1 1 1 Acetyl [N-Term] cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;membrane;nucleus protein binding;RNA binding;transporter activity "Pf02985, Pf03810, Pf13513" 16211 ENSMUSG00000001440.5 Kpnb1 11 Activation of DNA fragmentation factor; Neutrophil degranulation; Regulation of cholesterol biosynthesis by SREBP (SREBF) RNA transport 0 High P62960 Y-box-binding protein 1 OS=Mus musculus OX=10090 GN=Ybx1 PE=1 SV=3 0 11.359 27 3 5 3 322 35.7 9.88 3 5 3677098.281 3 Met-loss+Acetyl [N-Term] metabolic process;regulation of biological process cytoplasm;cytosol;extracellular;membrane;nucleus;spliceosomal complex DNA binding;protein binding;RNA binding Pf00313 22608 ENSMUSG00000028639.14 Ybx1 4 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway 0 High Q68FD5 Clathrin heavy chain 1 OS=Mus musculus OX=10090 GN=Cltc PE=1 SV=3 0 14.149 4 5 5 5 1675 191.4 5.69 4 1 4 1 4094561.5 2847668.484 1397681 3647034.375 5 3 2 2 cell differentiation;cell division;cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;cytosol;endosome;membrane;mitochondrion;vacuole protein binding;RNA binding;structural molecule activity "Pf00637, Pf01394, Pf04053, Pf09268, Pf13838" 67300 ENSMUSG00000047126.17 Cltc 11 "WNT5A-dependent internalization of FZD4; Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis; VLDLR internalisation and degradation; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Recycling pathway of L1; MHC class II antigen presentation; Cargo recognition for clathrin-mediated endocytosis; LDL clearance" Endocytosis; Endocrine and other factor-regulated calcium reabsorption; Lysosome; Huntington's disease; Synaptic vesicle cycle; Bacterial invasion of epithelial cells 0 High A0A2R8VK76 Cleavage and polyadenylation-specificity factor subunit 1 OS=Mus musculus OX=10090 GN=Cpsf1 PE=1 SV=1 0 9.21 4 5 5 5 1450 161.7 6.58 4 1 4 1 2956363.438 923138.5 3401304.375 2221339.75 4 1 2 1 0 High K3W4S6 Glycogenin OS=Mus musculus OX=10090 GN=Gyg PE=1 SV=1 0 7.364 8 3 5 3 377 41.9 6.02 3 1 4 1 5366589.563 1139158.375 2642730.75 3 1 1 catalytic activity Pf01501 ENSMUSG00000019528.18 3 0 High Q64435 UDP-glucuronosyltransferase 1-6 OS=Mus musculus OX=10090 GN=Ugt1a6 PE=1 SV=1 0 21.501 15 4 5 1 531 60.4 8.62 4 5 metabolic process endoplasmic reticulum;membrane catalytic activity;protein binding "Pf00201, Pf04101" 94284 ENSMUSG00000090124.7; ENSMUSG00000054545.17 Ugt1a6a 1 Glucuronidation Steroid hormone biosynthesis; Drug metabolism - cytochrome P450; Retinol metabolism; Metabolic pathways; Drug metabolism - other enzymes; Ascorbate and aldarate metabolism; Chemical carcinogenesis; Porphyrin and chlorophyll metabolism; Pentose and glucuronate interconversions; Metabolism of xenobiotics by cytochrome P450 0 High Q8BTI8 Serine/arginine repetitive matrix protein 2 OS=Mus musculus OX=10090 GN=Srrm2 PE=1 SV=3 0 14.38 2 5 5 5 2703 294.7 12.03 1 2 2 1 2 2 6819.488281 91425.17188 3161989.922 3946139 1 1 2 2 metabolic process nucleus;spliceosomal complex protein binding;RNA binding 75956 ENSMUSG00000039218.16 Srrm2 17 mRNA Splicing - Major Pathway 0 High P62862 40S ribosomal protein S30 OS=Mus musculus OX=10090 GN=Fau PE=1 SV=1 0 6.201 32 3 5 3 59 6.6 12.15 2 1 1 3 1 1 2257595.438 3239778.75 7614627.75 7527361.25 2 1 2 2 defense response;metabolic process;response to stimulus ribosome protein binding;RNA binding;structural molecule activity Pf04758 14109 Fau 19 0 High E9Q6R7 Utrophin OS=Mus musculus OX=10090 GN=Utrn PE=1 SV=1 0 17.875 2 4 5 4 3430 392.5 5.33 2 2 1 2 2 1 1606048.813 1027085 5269600.125 2491693.25 2 1 2 1 cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane metal ion binding;protein binding "Pf00307, Pf00397, Pf00435, Pf00569, Pf09068, Pf09069, Pf11971" 22288 ENSMUSG00000019820.10 Utrn 10 0 High Q9D7B7 Probable glutathione peroxidase 8 OS=Mus musculus OX=10090 GN=Gpx8 PE=1 SV=1 0 11.847 16 3 5 3 209 24.1 9.36 3 5 20707456 2 metabolic process;response to stimulus membrane antioxidant activity;catalytic activity "Pf00255, Pf00578" 69590 ENSMUSG00000021760.3 Gpx8 13 Detoxification of Reactive Oxygen Species Glutathione metabolism; Thyroid hormone synthesis; Arachidonic acid metabolism 0 High Q99JB2 "Stomatin-like protein 2, mitochondrial OS=Mus musculus OX=10090 GN=Stoml2 PE=1 SV=1" 0 12.645 13 4 5 4 353 38.4 8.87 4 1 4 1 6746101.875 2086746.625 1893593.625 9304774.5 4 1 1 3 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;membrane;mitochondrion protein binding Pf01145 66592 ENSMUSG00000028455.15 Stoml2 4 Processing of SMDT1 0 High A0A1Y7VM91 Ribitol-5-phosphate transferase OS=Mus musculus OX=10090 GN=Fktn PE=1 SV=1 0 15.64 13 5 5 5 500 58.2 8.41 5 5 9220886 2 cellular component movement;metabolic process;regulation of biological process endoplasmic reticulum;Golgi;membrane;nucleus catalytic activity Pf04991 246179 Fktn 4 0 High Q9QYR9 "Acyl-coenzyme A thioesterase 2, mitochondrial OS=Mus musculus OX=10090 GN=Acot2 PE=1 SV=2" 0 8.572 6 2 5 2 453 49.6 7.36 1 2 2 1 2 2 1851635.656 4021495.75 6485469.5 3 2 3 metabolic process;response to stimulus mitochondrion;organelle lumen catalytic activity;protein binding "Pf01738, Pf04775, Pf08840" 171210 ENSMUSG00000021226.7 Acot2 12 Mitochondrial Fatty Acid Beta-Oxidation Ovarian steroidogenesis; Metabolic pathways; Fatty acid elongation; Biosynthesis of unsaturated fatty acids 0 High A0A2I3BPG9 "Ribosomal protein L36A, pseudogene 1 OS=Mus musculus OX=10090 GN=Rpl36a-ps1 PE=3 SV=1" 0 5.282 18 2 5 2 106 12.4 10.51 2 2 2 3 1412370.5 9085861.25 7983713.75 15739551 1 2 2 2 0 High Q8BRK9 Alpha-mannosidase 2x OS=Mus musculus OX=10090 GN=Man2a2 PE=1 SV=2 0 19.793 5 5 5 4 1152 130.6 6.87 5 5 16909512.5 2 metabolic process Golgi;membrane catalytic activity;metal ion binding "Pf01074, Pf07748, Pf09261" 140481 ENSMUSG00000038886.10 Man2a2 7 Reactions specific to the complex N-glycan synthesis pathway Metabolic pathways; N-Glycan biosynthesis 1 High O08553 Dihydropyrimidinase-related protein 2 OS=Mus musculus OX=10090 GN=Dpysl2 PE=1 SV=2 0 10.576 10 5 5 5 572 62.2 6.38 5 5 2550120.594 1102762.875 1932936.625 4 1 1 cell differentiation;cell organization and biogenesis;cellular component movement;development;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;membrane;mitochondrion catalytic activity;protein binding "Pf01979, Pf07969, Pf13147, Pf13594" 12934 ENSMUSG00000022048.8 Dpysl2 14 Recycling pathway of L1; CRMPs in Sema3A signaling Axon guidance 0 High Q91WU0 Carboxylesterase 1F OS=Mus musculus OX=10090 GN=Ces1f PE=1 SV=1 0 7.828 6 3 5 2 561 61.6 6.48 3 5 metabolic process cytoplasm;cytosol;endoplasmic reticulum catalytic activity "Pf00135, Pf00326, Pf00756, Pf07859, Pf12695" 234564 ENSMUSG00000031725.8 Ces1f 8 Phase I - Functionalization of compounds 0 High Q62351 Transferrin receptor protein 1 OS=Mus musculus OX=10090 GN=Tfrc PE=1 SV=1 0 13.295 7 5 5 5 763 85.7 6.57 5 5 11309575.5 2 cell communication;cell differentiation;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;endosome;extracellular;membrane;mitochondrion;nucleus protein binding;receptor activity;RNA binding;transporter activity "Pf02225, Pf04253, Pf04389" 22042 ENSMUSG00000022797.15 Tfrc 16 Golgi Associated Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis; Transferrin endocytosis and recycling Endocytosis; Phagosome; HIF-1 signaling pathway; Hematopoietic cell lineage 0 High Q9DAW6 U4/U6 small nuclear ribonucleoprotein Prp4 OS=Mus musculus OX=10090 GN=Prpf4 PE=1 SV=1 0 13.013 10 4 5 4 521 58.3 7.28 1 4 1 4 2873001.25 9900109 1746822 1 2 1 metabolic process nucleus;spliceosomal complex protein binding;RNA binding "Pf00400, Pf08799" 70052 ENSMUSG00000066148.3 Prpf4 4 mRNA Splicing - Major Pathway Spliceosome 0 High K9J7B2 UDP-glucuronosyltransferase OS=Mus musculus OX=10090 GN=Ugt1a6b PE=1 SV=1 0 20.55 15 4 5 1 531 60.5 8.69 4 5 29135681.22 4 metabolic process endoplasmic reticulum;membrane catalytic activity;protein binding "Pf00201, Pf04101" 394435 ENSMUSG00000090145.7 Ugt1a6b 1 Glucuronidation Steroid hormone biosynthesis; Drug metabolism - cytochrome P450; Retinol metabolism; Metabolic pathways; Drug metabolism - other enzymes; Ascorbate and aldarate metabolism; Chemical carcinogenesis; Porphyrin and chlorophyll metabolism; Pentose and glucuronate interconversions; Metabolism of xenobiotics by cytochrome P450 3 High Q9D9V3 Ethylmalonyl-CoA decarboxylase OS=Mus musculus OX=10090 GN=Echdc1 PE=1 SV=2 0 7.44 8 3 5 3 322 35.4 7.01 1 3 1 4 1886977.875 2177229 12517668 2 1 2 metabolic process cytoplasm;cytosol;mitochondrion catalytic activity Pf00378 52665 ENSMUSG00000019883.11 Echdc1 10 Propanoate metabolism 0 High A0A0G2JF72 Cold shock domain-containing protein E1 OS=Mus musculus OX=10090 GN=Csde1 PE=1 SV=1 0 9.633 7 5 5 5 668 74.4 6.18 5 5 metabolic process;regulation of biological process cytoplasm;cytosol;Golgi;membrane DNA binding;RNA binding "Pf00313, Pf12901" 229663 ENSMUSG00000068823.10 Csde1 3 0 High Q9CXI0 "2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Mus musculus OX=10090 GN=Coq5 PE=1 SV=2" 0 21.08 22 5 5 5 327 37.3 7.49 5 5 489766.1875 10492218 1 2 metabolic process membrane;mitochondrion;organelle lumen catalytic activity "Pf01170, Pf01209, Pf08241, Pf08242, Pf12847, Pf13649, Pf13659, Pf13847" 52064 ENSMUSG00000041733.10 Coq5 5 Ubiquinone and other terpenoid-quinone biosynthesis; Metabolic pathways 0 High Q9D0S9 "Histidine triad nucleotide-binding protein 2, mitochondrial OS=Mus musculus OX=10090 GN=Hint2 PE=1 SV=1" 0 20.966 40 4 5 4 163 17.3 9.82 3 1 4 1 12266271.94 7079263.625 4809831.5 6335832.5 4 3 2 2 cell death;metabolic process;regulation of biological process mitochondrion catalytic activity;nucleotide binding "Pf01230, Pf11969" 68917 ENSMUSG00000028470.10 Hint2 4 0 High E9Q1K3 Alpha-adducin OS=Mus musculus OX=10090 GN=Add1 PE=1 SV=1 0 8.484 7 3 5 3 660 72.9 6.32 2 2 1 2 2 1 1395647.438 1628446.625 5156226.25 5206660.375 2 1 2 2 cell differentiation;cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane;nucleus protein binding;RNA binding;structural molecule activity Pf00596 11518 ENSMUSG00000029106.14 Add1 5 0 High A0A338P731 40S ribosomal protein S10 (Fragment) OS=Mus musculus OX=10090 GN=Rps10 PE=1 SV=1 0 5.597 15 2 5 2 107 12.8 10.04 1 1 1 2 1 1 1 2 6612184.5 9793738 23622761 1 1 2 0 High A0A075B5K6 Immunoglobulin kappa variable 2-109 (Fragment) OS=Mus musculus OX=10090 GN=Igkv2-109 PE=4 SV=4 0 3.978 11 1 5 1 120 13 7.12 1 1 1 1 2 1 1 1 13272665 6276168.5 9136637 5434413.5 1 1 1 1 response to stimulus "Pf07679, Pf07686" 628268 ENSMUSG00000105606.1 Igkv2-109 6 0 High Q5SUF2 Luc7-like protein 3 OS=Mus musculus OX=10090 GN=Luc7l3 PE=1 SV=1 0 11.768 9 3 5 3 432 51.4 9.77 1 3 1 1 3 1 51357.83203 131530.1211 3119723.75 71393.38281 1 2 2 1 Acetyl [N-Term] cell organization and biogenesis;metabolic process nucleus;spliceosomal complex DNA binding;RNA binding Pf03194 67684 ENSMUSG00000020863.15 Luc7l3 11 0 High Q8R180 ERO1-like protein alpha OS=Mus musculus OX=10090 GN=Ero1a PE=1 SV=2 0 12.627 10 4 5 4 464 54.1 6.54 4 5 9431832 1 cell death;cell differentiation;cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport endoplasmic reticulum;membrane catalytic activity Pf04137 50527 ENSMUSG00000021831.8 Ero1l 14 Insulin processing; Detoxification of Reactive Oxygen Species Protein processing in endoplasmic reticulum 0 High Q3U367 4-trimethylaminobutyraldehyde dehydrogenase OS=Mus musculus OX=10090 GN=Aldh9a1 PE=1 SV=1 0 12.565 7 3 5 3 518 55.9 7.46 3 2 3 2 3690282.625 1033002.625 10254817.5 3 1 3 metabolic process cytoplasm;cytosol;mitochondrion catalytic activity;nucleotide binding;protein binding Pf00171 56752 ENSMUSG00000026687.14 Aldh9a1 1 Carnitine synthesis "Histidine metabolism; Pyruvate metabolism; Arginine and proline metabolism; Tryptophan metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Lysine degradation; Fatty acid degradation; Glycolysis / Gluconeogenesis; beta-Alanine metabolism; Ascorbate and aldarate metabolism; Glycerolipid metabolism" 0 High Q99LI7 Cleavage stimulation factor subunit 3 OS=Mus musculus OX=10090 GN=Cstf3 PE=1 SV=1 0 15.218 8 4 5 4 717 82.8 8.12 1 3 1 1 3 1 717956.875 2371262.75 8944627 5032794 2 1 2 1 metabolic process nucleus protein binding;RNA binding Pf05843 228410 ENSMUSG00000027176.8 Cstf3 2 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Processing of Intronless Pre-mRNAs; Cleavage of Growing Transcript in the Termination Region mRNA surveillance pathway 0 High Q60710 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 OS=Mus musculus OX=10090 GN=Samhd1 PE=1 SV=3 0 15.566 8 3 5 3 658 75.8 7.93 2 1 2 2 1 2 206515.8594 1858377.75 3784851.75 1 1 2 0 High P62751 60S ribosomal protein L23a OS=Mus musculus OX=10090 GN=Rpl23a PE=1 SV=1 0 4.477 8 1 5 1 156 17.7 10.45 1 1 1 1 2 2 3607626.25 7478331.5 9465357 9714716 1 1 1 1 cell organization and biogenesis;metabolic process nucleus;ribosome protein binding;RNA binding;structural molecule activity "Pf00276, Pf03939" 268449 ENSMUSG00000058546.8 Rpl23a 11 Ribosome 0 Medium Q9ES03 T-box transcription factor TBX20 OS=Mus musculus OX=10090 GN=Tbx20 PE=2 SV=3 0.02 1.34 3 1 5 1 445 49.1 7.71 1 1 2 3 6497053 10320193 23230700 50598312 1 1 1 1 Acetyl [N-Term] cell differentiation;cell proliferation;cellular component movement;development;metabolic process;regulation of biological process cytoplasm;nucleus DNA binding;protein binding "Pf00907, Pf05872" 57246 ENSMUSG00000031965.15 Tbx20 9 0 High P58064 "28S ribosomal protein S6, mitochondrial OS=Mus musculus OX=10090 GN=Mrps6 PE=1 SV=3" 0 6.945 22 3 5 3 125 14.3 9.5 2 1 2 2 1 2 481596.4375 5364282.5 4381507.375 5227116.375 2 2 2 2 cell organization and biogenesis;metabolic process mitochondrion;ribosome RNA binding;structural molecule activity Pf01250 121022 ENSMUSG00000039680.9 Mrps6 16 Mitochondrial translation termination; Mitochondrial translation elongation Ribosome 0 High Q02257 Junction plakoglobin OS=Mus musculus OX=10090 GN=Jup PE=1 SV=3 0 19.76 12 5 5 5 745 81.7 6.14 1 4 1 4 1536134.5 1376886.625 13877083 2 1 4 cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane;nucleus protein binding;signal transducer activity;structural molecule activity Pf00514 16480 ENSMUSG00000001552.14 Jup 11 Formation of the cornified envelope; VEGFR2 mediated vascular permeability; Neutrophil degranulation; Adherens junctions interactions Acute myeloid leukemia; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Transcriptional misregulation in cancer; Pathways in cancer 0 High O35488 Very long-chain acyl-CoA synthetase OS=Mus musculus OX=10090 GN=Slc27a2 PE=1 SV=2 0 23.023 15 5 5 5 620 70.4 8.9 5 5 174426.1563 2698125.375 1 2 metabolic process;transport endoplasmic reticulum;membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding;protein binding;transporter activity "Pf00501, Pf13193" 26458 ENSMUSG00000027359.16 Slc27a2 2 Alpha-oxidation of phytanate; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; Neutrophil degranulation; Synthesis of bile acids and bile salts via 24-hydroxycholesterol PPAR signaling pathway; Insulin resistance; Peroxisome 0 High Q5SX75 Procollagen-proline 4-dioxygenase OS=Mus musculus OX=10090 GN=P4ha2 PE=1 SV=1 0 15.104 9 4 5 4 537 61 5.9 4 5 277147.0313 11105289 1 3 metabolic process cytosol;endoplasmic reticulum catalytic activity;metal ion binding;protein binding "Pf03171, Pf08336, Pf13640" 18452 ENSMUSG00000018906.14 P4ha2 11 Arginine and proline metabolism; Metabolic pathways 0 High A2A8U2 Transmembrane protein 201 OS=Mus musculus OX=10090 GN=Tmem201 PE=1 SV=1 0 13.032 8 5 5 5 664 72.5 9.2 1 4 1 4 2963608.75 11373815.5 1 2 cell organization and biogenesis;cellular component movement membrane;nucleus protein binding "Pf09779, Pf10476" 230917 ENSMUSG00000044700.15 Tmem201 4 0 High Q8VCW8 "Medium-chain acyl-CoA ligase ACSF2, mitochondrial OS=Mus musculus OX=10090 GN=Acsf2 PE=1 SV=1" 0 16.512 11 5 5 5 615 67.9 8.18 1 4 1 4 660505.375 1297137.625 8855609.5 1 1 2 metabolic process mitochondrion catalytic activity;nucleotide binding "Pf00501, Pf13193" 264895 ENSMUSG00000076435.3 Acsf2 11 Mitochondrial Fatty Acid Beta-Oxidation 0 High Q7TN22 Thioredoxin domain-containing protein 16 OS=Mus musculus OX=10090 GN=Txndc16 PE=2 SV=1 0 15.871 7 5 5 5 820 92 5.31 5 5 4077723.188 2 cellular homeostasis;regulation of biological process endoplasmic reticulum;extracellular;organelle lumen "Pf00085, Pf13848" 70561 ENSMUSG00000021830.13 Txndc16 14 0 High P62307 Small nuclear ribonucleoprotein F OS=Mus musculus OX=10090 GN=Snrpf PE=1 SV=1 0 10.506 50 3 5 3 86 9.7 4.67 1 1 3 1 1 3 858883.375 9093003 28968561 155782264.1 1 2 2 2 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process cytoplasm;cytosol;nucleus;spliceosomal complex RNA binding Pf01423 69878 ENSMUSG00000020018.6 Snrpf 10 mRNA Splicing - Minor Pathway; Cleavage of Growing Transcript in the Termination Region ; mRNA Splicing - Major Pathway; snRNP Assembly; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs; SLBP independent Processing of Histone Pre-mRNAs Spliceosome 0 High Q9EP89 "Serine beta-lactamase-like protein LACTB, mitochondrial OS=Mus musculus OX=10090 GN=Lactb PE=1 SV=1" 0 7.104 7 4 5 4 551 60.7 8.9 4 5 3224347.813 1505730.625 3 1 metabolic process;regulation of biological process cytosol;membrane;mitochondrion catalytic activity;protein binding Pf00144 80907 ENSMUSG00000032370.8 Lactb 9 0 Medium Q7SIG6 "Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 OS=Mus musculus OX=10090 GN=Asap2 PE=1 SV=3" 0.017 1.375 1 1 5 1 958 106.7 6.65 1 1 1 1 1 3 46577416 44574812 55257640 343346624 1 1 1 1 regulation of biological process cytoplasm;Golgi;membrane enzyme regulator activity;metal ion binding;protein binding "Pf00018, Pf00023, Pf00169, Pf01412, Pf07653, Pf12796, Pf13637, Pf13857, Pf14604" 211914 ENSMUSG00000052632.15 Asap2 12 Endocytosis; Fc gamma R-mediated phagocytosis 0 High Q99KP6 Pre-mRNA-processing factor 19 OS=Mus musculus OX=10090 GN=Prpf19 PE=1 SV=1 0 9.928 8 3 5 3 504 55.2 6.61 2 2 2 3 600354.4688 6404153.25 8911135 2328376.5 2 3 3 1 cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane;nucleus;spliceosomal complex catalytic activity;metal ion binding;protein binding "Pf00400, Pf04564, Pf08606, Pf11789" 28000 ENSMUSG00000024735.13 Prpf19 19 mRNA Splicing - Major Pathway; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of TC-NER Pre-Incision Complex Ubiquitin mediated proteolysis; Spliceosome 0 High P99028 "Cytochrome b-c1 complex subunit 6, mitochondrial OS=Mus musculus OX=10090 GN=Uqcrh PE=1 SV=2" 0 12.277 20 1 5 1 89 10.4 4.87 1 1 1 1 1 1 2 1 6471700.5 4293990 18008484 1 1 1 cell organization and biogenesis;metabolic process;transport membrane;mitochondrion catalytic activity;protein binding;transporter activity Pf02320 66576 ENSMUSG00000063882.12 Uqcrh 4 Respiratory electron transport Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 High P28798 Progranulin OS=Mus musculus OX=10090 GN=Grn PE=1 SV=2 0 19.483 14 4 5 4 589 63.4 6.8 1 3 1 4 12066611 29198168 16813348 1701208 1 1 1 1 cell proliferation;regulation of biological process;response to stimulus;transport endoplasmic reticulum;endosome;extracellular;mitochondrion;vacuole protein binding;RNA binding Pf00396 14824 Grn 11 0 High F6ZKZ3 "Sulfide:quinone oxidoreductase, mitochondrial OS=Mus musculus OX=10090 GN=Sqor PE=1 SV=1" 0 14.396 12 4 5 4 300 33.1 8.95 4 5 4127481.75 1780483.125 2820531.75 21907285.75 1 1 1 4 metabolic process catalytic activity "Pf07992, Pf13738" ENSMUSG00000005803.14 2 0 High P60882 Multiple epidermal growth factor-like domains protein 8 OS=Mus musculus OX=10090 GN=Megf8 PE=1 SV=2 0 15.765 2 5 5 5 2789 297.3 6.8 5 5 7117419.5 2 cellular component movement;regulation of biological process;response to stimulus membrane;nucleus metal ion binding;protein binding "Pf00053, Pf00431, Pf01344, Pf07645, Pf12947, Pf13415, Pf13418, Pf13854" 269878 ENSMUSG00000045039.9 Megf8 7 0 High A0A075B5W7 Immunoglobulin heavy variable 1-56 OS=Mus musculus OX=10090 GN=Ighv1-56 PE=4 SV=1 0 9.661 19 1 5 1 98 10.8 8.47 1 1 1 2 1 2 3027716.5 4635475 3880651.25 1785849.25 1 1 1 1 Pf07686 ENSMUSG00000094862.2 LOC673634 12 0 High E9PVB5 Tetratricopeptide repeat protein 17 OS=Mus musculus OX=10090 GN=Ttc17 PE=1 SV=1 0 9.755 6 4 4 4 1198 135.4 6.47 4 4 306719.7813 9154294 1 2 cell organization and biogenesis cytoplasm;cytoskeleton;cytosol;membrane catalytic activity;nucleotide binding;protein binding "Pf00515, Pf02841, Pf13414, Pf13424, Pf13432" 74569 ENSMUSG00000027194.16 Ttc17 2 0 High Q922B1 ADP-ribose glycohydrolase MACROD1 OS=Mus musculus OX=10090 GN=Macrod1 PE=1 SV=2 0 13.522 16 2 4 2 323 35.3 8.85 1 1 1 1 1 1 1 1 509843.7813 1 metabolic process;response to stimulus mitochondrion;nucleus catalytic activity Pf01661 107227 ENSMUSG00000036278.6 Macrod1 19 0 High Q99LC2 Cleavage stimulation factor subunit 1 OS=Mus musculus OX=10090 GN=Cstf1 PE=1 SV=1 0 12.94 14 4 4 4 431 48.4 6.58 4 4 1113518.375 11184795.5 7676786.25 1 3 2 metabolic process nucleus protein binding;RNA binding "Pf00400, Pf11768" 67337 ENSMUSG00000027498.14 Cstf1 2 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Processing of Intronless Pre-mRNAs; Cleavage of Growing Transcript in the Termination Region mRNA surveillance pathway 0 High Q60972 Histone-binding protein RBBP4 OS=Mus musculus OX=10090 GN=Rbbp4 PE=1 SV=5 0 10.117 7 2 4 2 425 47.6 4.89 1 2 1 1 2 1 398975.1563 2795369.25 5104999.5 4097985.5 1 1 1 1 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytosol;nucleus catalytic activity;DNA binding;protein binding "Pf00400, Pf12265" 19646 ENSMUSG00000057236.10 Rbbp4 4 Oxidative Stress Induced Senescence; Deposition of new CENPA-containing nucleosomes at the centromere; RNA Polymerase I Transcription Initiation; PRC2 methylates histones and DNA; G0 and Early G1; NoRC negatively regulates rRNA expression; Regulation of PTEN gene transcription; Regulation of TP53 Activity through Acetylation; PKMTs methylate histone lysines; Mus musculus biological processes; Transcriptional Regulation by E2F6 0 High O35218 Cleavage and polyadenylation specificity factor subunit 2 OS=Mus musculus OX=10090 GN=Cpsf2 PE=1 SV=1 0 8.619 5 4 4 4 782 88.3 5.11 3 1 3 1 1620956.5 3519202 10444082 2 2 1 metabolic process membrane;nucleus RNA binding "Pf00753, Pf07521, Pf10996, Pf12706, Pf13299" 51786 ENSMUSG00000041781.8 Cpsf2 12 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Processing of Intronless Pre-mRNAs; Cleavage of Growing Transcript in the Termination Region mRNA surveillance pathway 0 High F6RDI8 Serine and arginine-rich-splicing factor 11 (Fragment) OS=Mus musculus OX=10090 GN=Srsf11 PE=1 SV=1 0 8.318 8 3 4 3 500 55.8 10.61 3 4 metabolic process RNA binding "Pf00076, Pf13893, Pf14259" ENSMUSG00000055436.18 3 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript 0 High P41105 60S ribosomal protein L28 OS=Mus musculus OX=10090 GN=Rpl28 PE=1 SV=2 0 10.516 28 4 4 4 137 15.7 12.02 4 4 1708263.25 7442141 8069850.25 27340994.5 1 2 2 4 Met-loss+Acetyl [N-Term] metabolic process;regulation of biological process membrane;ribosome RNA binding;structural molecule activity Pf01778 19943 ENSMUSG00000030432.12 Rpl28 7 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q99LC9 Peroxisome assembly factor 2 OS=Mus musculus OX=10090 GN=Pex6 PE=1 SV=1 0 9.964 3 3 4 3 981 104.5 7.34 3 4 cell organization and biogenesis;regulation of biological process;transport cytoplasm;cytosol;membrane catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00004, Pf00910, Pf05729, Pf07724, Pf13086, Pf13191, Pf13207, Pf13245" 224824 ENSMUSG00000002763.16 Pex6 17 Peroxisome 0 High Q99JR1 Sideroflexin-1 OS=Mus musculus OX=10090 GN=Sfxn1 PE=1 SV=3 0 19.787 23 4 4 4 322 35.6 9.23 4 4 315051.2422 179003.5469 16624824.5 2 1 4 cell differentiation;transport membrane;mitochondrion transporter activity Pf03820 14057 ENSMUSG00000021474.8 Sfxn1 13 0 High D3YUM1 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Mus musculus OX=10090 GN=Ndufv1 PE=1 SV=1" 0 7.312 6 3 4 3 455 49.9 8.07 2 2 2 2 2069194.563 1064654.375 9978664.5 3 1 2 metabolic process;transport membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding "Pf01512, Pf10531, Pf10589" ENSMUSG00000037916.13 19 0 High Q9CQS3 Fin bud initiation factor homolog OS=Mus musculus OX=10090 GN=Fibin PE=2 SV=1 0 12.274 16 3 4 3 217 24.7 5.66 1 3 1 3 764732.4844 11929252 2 2 response to stimulus endoplasmic reticulum;extracellular;Golgi protein binding 67606 ENSMUSG00000074971.4 Fibin 2 0 High Q06185 "ATP synthase subunit e, mitochondrial OS=Mus musculus OX=10090 GN=Atp5me PE=1 SV=2" 0 3.914 17 1 4 1 71 8.2 9.35 1 1 1 3 825537.9375 1282339.125 2217385.5 12619566 1 1 1 1 metabolic process;transport membrane;mitochondrion catalytic activity;transporter activity Pf05680 11958 ENSMUSG00000050856.16 Atp5k 5 Cristae formation; Formation of ATP by chemiosmotic coupling Metabolic pathways; Oxidative phosphorylation 0 High P26039 Talin-1 OS=Mus musculus OX=10090 GN=Tln1 PE=1 SV=2 0 11.583 3 4 4 4 2541 269.7 6.18 3 1 3 1 1139251.875 2 cell organization and biogenesis;regulation of biological process;response to stimulus cell surface;cytoplasm;cytoskeleton;membrane protein binding;structural molecule activity "Pf00373, Pf01608, Pf02174, Pf08913, Pf09141, Pf09379" 21894 ENSMUSG00000028465.16 Tln1 4 p130Cas linkage to MAPK signaling for integrins; GRB2:SOS provides linkage to MAPK signaling for Integrins ; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion; Platelet degranulation ; Smooth Muscle Contraction Focal adhesion; Platelet activation; HTLV-I infection; Rap1 signaling pathway 0 High Q8K4Z3 NAD(P)H-hydrate epimerase OS=Mus musculus OX=10090 GN=Naxe PE=1 SV=1 0 7.955 11 3 4 3 282 31 7.69 3 4 199020.625 26922030.5 1 3 cell organization and biogenesis;metabolic process cytosol;extracellular;mitochondrion;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding Pf03853 246703 ENSMUSG00000028070.7 Apoa1bp; Naxe 3 Nicotinamide salvaging 0 High P63085 Mitogen-activated protein kinase 1 OS=Mus musculus OX=10090 GN=Mapk1 PE=1 SV=3 0 5.971 8 3 4 3 358 41.2 6.98 3 4 2124884.313 730451.1875 1033258.313 3072258.25 3 1 1 1 Met-loss+Acetyl [N-Term] cell communication;cell death;cell differentiation;cell proliferation;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;endosome;Golgi;membrane;mitochondrion;nucleus catalytic activity;nucleotide binding;protein binding;signal transducer activity "Pf00069, Pf01636, Pf07714" 26413 ENSMUSG00000063358.15 Mapk1 16 "NCAM signaling for neurite out-growth; MAP2K and MAPK activation; Spry regulation of FGF signaling; Signal transduction by L1; FCERI mediated MAPK activation; phospho-PLA2 pathway; Regulation of HSF1-mediated heat shock response; Activated TLR4 signalling; Signaling by GPCR; Neutrophil degranulation; Gastrin-CREB signalling pathway via PKC and MAPK; MAPK1 (ERK2) activation; Recycling pathway of L1; Thrombin signalling through proteinase activated receptors (PARs); RHO GTPases Activate WASPs and WAVEs; Golgi Cisternae Pericentriolar Stack Reorganization; Interleukin-20 family signaling; RSK activation; Regulation of actin dynamics for phagocytic cup formation; Activation of the AP-1 family of transcription factors; Growth hormone receptor signaling; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Oxidative Stress Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); Oncogene Induced Senescence; ERKs are inactivated; Negative feedback regulation of MAPK pathway" Oxytocin signaling pathway; ErbB signaling pathway; FoxO signaling pathway; Acute myeloid leukemia; AGE-RAGE signaling pathway in diabetic complications; mTOR signaling pathway; Cholinergic synapse; Platinum drug resistance; Chagas disease (American trypanosomiasis); T cell receptor signaling pathway; Phospholipase D signaling pathway; Retrograde endocannabinoid signaling; Regulation of actin cytoskeleton; MAPK signaling pathway; Type II diabetes mellitus; Progesterone-mediated oocyte maturation; Ras signaling pathway; Prolactin signaling pathway; TNF signaling pathway; VEGF signaling pathway; Focal adhesion; NOD-like receptor signaling pathway; Insulin signaling pathway; Endometrial cancer; Long-term potentiation; Toxoplasmosis; Chemokine signaling pathway; Breast cancer; Melanoma; Platelet activation; Signaling pathways regulating pluripotency of stem cells; Tuberculosis; Melanogenesis; Hepatitis B; Axon guidance; Oocyte meiosis; Osteoclast differentiation; Non-small cell lung cancer; Adherens junction; Sphingolipid signaling pathway; B cell receptor signaling pathway; Dorso-ventral axis formation; Glutamatergic synapse; Toll-like receptor signaling pathway; Pertussis; Proteoglycans in cancer; Salmonella infection; Fc gamma R-mediated phagocytosis; Thyroid hormone signaling pathway; Neurotrophin signaling pathway; Long-term depression; cGMP-PKG signaling pathway; TGF-beta signaling pathway; Rap1 signaling pathway; HIF-1 signaling pathway; Pathways in cancer; Influenza A; Hepatitis C; Alzheimer's disease; Alcoholism; Pancreatic cancer; Thyroid cancer; PI3K-Akt signaling pathway; cAMP signaling pathway; Vascular smooth muscle contraction; Renal cell carcinoma; GnRH signaling pathway; Natural killer cell mediated cytotoxicity; Prion diseases; Gap junction; Circadian entrainment; Glioma; Fc epsilon RI signaling pathway; EGFR tyrosine kinase inhibitor resistance; Leishmaniasis; Central carbon metabolism in cancer; Choline metabolism in cancer; Estrogen signaling pathway; Th1 and Th2 cell differentiation; Colorectal cancer; Viral carcinogenesis; Chronic myeloid leukemia; Serotonergic synapse; Adrenergic signaling in cardiomyocytes; Prostate cancer; Endocrine resistance; Bladder cancer; Aldosterone-regulated sodium reabsorption; Apoptosis 0 High D3YVC9 Graves disease carrier protein homolog (Fragment) OS=Mus musculus OX=10090 GN=Slc25a16 PE=1 SV=1 0 9.912 9 3 4 3 322 34.9 9.95 3 4 268828.0625 13939551.5 1 2 transport membrane;mitochondrion Pf00153 ENSMUSG00000071253.8 10 0 High E9Q3W4 Plectin OS=Mus musculus OX=10090 GN=Plec PE=1 SV=1 0 7.977 1 4 4 4 4386 498.8 5.68 4 4 1358065.094 3 cell organization and biogenesis;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane protein binding;RNA binding;structural molecule activity "Pf00307, Pf00681, Pf07812, Pf11971" 18810 ENSMUSG00000022565.15 Plec 15 0 High Q91VS7 Microsomal glutathione S-transferase 1 OS=Mus musculus OX=10090 GN=Mgst1 PE=1 SV=3 0 8.936 12 2 4 2 155 17.5 9.66 1 2 1 3 662282.9375 7039577.25 1 1 cell organization and biogenesis;metabolic process;response to stimulus endoplasmic reticulum;membrane;mitochondrion;nucleus antioxidant activity;catalytic activity;protein binding Pf01124 56615 ENSMUSG00000008540.11 Mgst1 6 Glutathione conjugation; Aflatoxin activation and detoxification; Neutrophil degranulation Glutathione metabolism; Platinum drug resistance; Drug metabolism - cytochrome P450; Chemical carcinogenesis; Metabolism of xenobiotics by cytochrome P450 0 High Q3TIX9 U4/U6.U5 tri-snRNP-associated protein 2 OS=Mus musculus OX=10090 GN=Usp39 PE=1 SV=2 0 12.445 9 3 4 3 564 65.1 8.9 1 3 1 3 223947.8906 1701443.375 1 1 cell division;cell organization and biogenesis;metabolic process nucleus;spliceosomal complex catalytic activity;metal ion binding "Pf00443, Pf02148" 28035 ENSMUSG00000056305.4; ENSMUSG00000104250.2 Usp39 6; CHR_MG184_PATCH mRNA Splicing - Major Pathway Spliceosome 0 High Q8R0Y6 Cytosolic 10-formyltetrahydrofolate dehydrogenase OS=Mus musculus OX=10090 GN=Aldh1l1 PE=1 SV=1 0 5.82 4 3 4 3 902 98.6 5.91 3 4 1752902.5 2 metabolic process cytoplasm;cytosol;mitochondrion catalytic activity;protein binding "Pf00171, Pf00550, Pf00551, Pf02911" 107747 ENSMUSG00000030088.15 Aldh1l1 6 Metabolism of folate and pterines One carbon pool by folate 0 High Q62264 Thyroid hormone-inducible hepatic protein OS=Mus musculus OX=10090 GN=Thrsp PE=1 SV=1 0 11.241 26 2 4 2 150 17.1 4.98 2 1 3 1 2839451.188 1244279.125 2510127.125 2 1 2 metabolic process;regulation of biological process cytoplasm;cytosol;nucleus protein binding Pf07084 21835 ENSMUSG00000035686.8 Thrsp 7 Import of palmitoyl-CoA into the mitochondrial matrix 0 High Q02053 Ubiquitin-like modifier-activating enzyme 1 OS=Mus musculus OX=10090 GN=Uba1 PE=1 SV=1 0 11.811 5 4 4 4 1058 117.7 5.66 4 4 354087.25 1597208.25 1601271.375 7621714.25 2 1 1 2 metabolic process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00899, Pf02134, Pf09358, Pf10585" 22201 ENSMUSG00000001924.15 Uba1 X Antigen processing: Ubiquitination & Proteasome degradation; Synthesis of active ubiquitin: roles of E1 and E2 enzymes Ubiquitin mediated proteolysis; Parkinson's disease 0 High A0A0A6YXQ0 Immunoglobulin heavy variable 8-8 (Fragment) OS=Mus musculus OX=10090 GN=Ighv8-8 PE=4 SV=1 0 7.272 18 2 4 1 119 13.2 8.84 2 1 1 2 1 1 5333204.5 4499558.5 4057821.75 1 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000104452.1 12 Regulation of Complement cascade; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Cell surface interactions at the vascular wall; FCERI mediated NF-kB activation; Role of LAT2/NTAL/LAB on calcium mobilization; Role of phospholipids in phagocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR activation; Classical antibody-mediated complement activation; FCERI mediated Ca+2 mobilization; FCERI mediated MAPK activation; CD22 mediated BCR regulation; Scavenging of heme from plasma 0 High Q64442 Sorbitol dehydrogenase OS=Mus musculus OX=10090 GN=Sord PE=1 SV=3 0 8.37 10 3 4 3 357 38.2 7.02 3 4 3769221.938 1848317.375 3 1 Met-loss+Acetyl [N-Term] cellular component movement;metabolic process;response to stimulus membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00107, Pf08240" 20322 ENSMUSG00000027227.7 Sord 2 Fructose biosynthesis; Catabolism of glucuronate to xylulose-5-phosphate Metabolic pathways; Fructose and mannose metabolism; Pentose and glucuronate interconversions 0 High D3Z7X0 "Acyl-Coenzyme A dehydrogenase family, member 12 OS=Mus musculus OX=10090 GN=Acad12 PE=1 SV=1" 0 7.792 7 3 4 3 555 61.4 9.36 2 1 1 2 1 1 1603210.063 4450329.125 1905659.25 2756047.75 2 2 1 1 metabolic process mitochondrion catalytic activity;nucleotide binding "Pf00441, Pf02770, Pf02771, Pf08028" 338350 ENSMUSG00000042647.13 Acad12 5 Mitochondrial Fatty Acid Beta-Oxidation 0 High P43024 "Cytochrome c oxidase subunit 6A1, mitochondrial OS=Mus musculus OX=10090 GN=Cox6a1 PE=1 SV=2" 0 9.158 61 3 4 3 111 12.3 9.98 3 4 554967 7098513.25 1 2 metabolic process;regulation of biological process;transport membrane;mitochondrion catalytic activity;enzyme regulator activity;transporter activity Pf02046 12861 Cox6a1 5 Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 High E0CYC4 Cyclin-dependent kinase 8 (Fragment) OS=Mus musculus OX=10090 GN=Cdk8 PE=1 SV=1 0 10.631 18 4 4 4 245 28.5 8.98 4 4 4635211.875 1614691.125 4 1 metabolic process catalytic activity;nucleotide binding "Pf00069, Pf07714" ENSMUSG00000029635.15 5 0 High Q7TQG0 Zinc finger and BTB domain-containing protein 5 OS=Mus musculus OX=10090 GN=Zbtb5 PE=2 SV=1 0 8.255 7 2 4 2 670 73.2 6.25 2 1 1 2 1 1 494773.7813 1 metabolic process;regulation of biological process nucleus DNA binding;metal ion binding;protein binding "Pf00096, Pf00651, Pf13465" 230119 ENSMUSG00000049657.9 Zbtb5 4 0 High F6VT60 AFG1-like ATPase (Fragment) OS=Mus musculus OX=10090 GN=Afg1l PE=1 SV=1 0 8.558 12 3 4 3 348 40 6.87 3 4 429500.25 680766.875 15577252 1 1 2 mitochondrion nucleotide binding Pf03969 ENSMUSG00000038302.14 10 0 High Q07417 "Short-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Acads PE=1 SV=2" 0 7.108 9 2 4 2 412 44.9 8.47 1 2 1 1 2 1 1270253.75 2191186.25 3184901.25 2 1 1 cell organization and biogenesis;metabolic process membrane;mitochondrion;nucleus;organelle lumen catalytic activity;nucleotide binding "Pf00441, Pf02770, Pf02771, Pf08028" 11409 ENSMUSG00000029545.13 Acads 5 Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA "Fatty acid metabolism; Valine, leucine and isoleucine degradation; Metabolic pathways; Fatty acid degradation; Butanoate metabolism; Carbon metabolism" 0 Medium F8VPV0 Pericentrin OS=Mus musculus OX=10090 GN=Pcnt PE=1 SV=1 0.047 1.025 0 1 4 1 2916 331.1 5.38 1 1 1 1 2 1 1000941.688 7421411.5 15769446 8961587 1 1 1 1 cell organization and biogenesis;cell proliferation;cellular component movement;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane protein binding;structural molecule activity "Pf09731, Pf10495" 18541 ENSMUSG00000001151.10 Pcnt 10 Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes 0 High Q99J47 Dehydrogenase/reductase SDR family member 7B OS=Mus musculus OX=10090 GN=Dhrs7b PE=1 SV=1 0 15.969 18 4 4 4 323 35 9.63 4 4 19698703.5 3 cell differentiation;metabolic process endoplasmic reticulum;membrane catalytic activity "Pf00106, Pf08659, Pf13460, Pf13561" 216820 ENSMUSG00000042569.13 Dhrs7b 11 0 High Q3UXJ2 Transforming growth factor-beta-induced protein ig-h3 OS=Mus musculus OX=10090 GN=Tgfbi PE=1 SV=1 0 10.249 6 3 4 3 651 70.9 7.03 3 4 3743141.438 3085169.375 1746535 1695463.125 3 2 1 1 cell organization and biogenesis;cell proliferation extracellular protein binding "Pf02469, Pf07546" 21810 Tgfbi 13 0 Low U5KVR9 Centrosomal protein of 63 kDa OS=Mus musculus OX=10090 GN=Cep63 PE=1 SV=1 0.078 0.807 1 1 4 1 596 68.9 5.74 1 1 1 3 3772340.5 11704850 112759576 1 1 1 cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytoskeleton protein binding 28135 ENSMUSG00000032534.18 Cep63 9 0 High P97315 Cysteine and glycine-rich protein 1 OS=Mus musculus OX=10090 GN=Csrp1 PE=1 SV=3 0 10.311 29 3 4 3 193 20.6 8.57 3 4 2563471.75 2 cell organization and biogenesis cytoskeleton;nucleus metal ion binding;protein binding;RNA binding Pf00412 13007 ENSMUSG00000026421.14 Csrp1 1 0 High Q9R1E6 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 OS=Mus musculus OX=10090 GN=Enpp2 PE=1 SV=3 0 11.681 5 4 4 4 862 98.8 7.27 4 4 11021956 2 cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;extracellular;Golgi;ribosome catalytic activity;metal ion binding;receptor activity;structural molecule activity "Pf01033, Pf01223, Pf01663" 18606 ENSMUSG00000022425.15 Enpp2 15 Ether lipid metabolism 0 High Q9R233 Tapasin OS=Mus musculus OX=10090 GN=Tapbp PE=1 SV=2 0 9.283 6 3 4 3 465 49.7 8.5 3 4 85364.50781 13377284.5 1 2 defense response;metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;membrane protein binding Pf07654 21356 Tapbp 17 Antigen processing and presentation 0 High E9Q5L3 "Short/branched chain-specific acyl-CoA dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Acadsb PE=1 SV=1" 0 11.571 9 3 4 3 465 51.8 8.32 1 2 2 2 2425845.719 11581931 3 3 metabolic process membrane catalytic activity;nucleotide binding "Pf00441, Pf02770, Pf02771, Pf08028" ENSMUSG00000030861.15 7 0 High Q99LP6 "GrpE protein homolog 1, mitochondrial OS=Mus musculus OX=10090 GN=Grpel1 PE=1 SV=1" 0 8.871 24 4 4 4 217 24.3 8.38 1 2 1 1 2 1 2009078.813 1719995.25 3472428.75 2 1 1 metabolic process;regulation of biological process;transport mitochondrion;nucleus;organelle lumen enzyme regulator activity;nucleotide binding;protein binding Pf01025 17713 ENSMUSG00000029198.3 Grpel1 5 0 High P61750 ADP-ribosylation factor 4 OS=Mus musculus OX=10090 GN=Arf4 PE=1 SV=2 0 9.331 19 3 4 3 180 20.4 7.14 3 4 657101.7969 3060945.75 133526.6719 24136195.02 2 2 1 3 cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;Golgi;membrane catalytic activity;nucleotide binding;protein binding;signal transducer activity "Pf00025, Pf00071, Pf00503, Pf04670, Pf08477, Pf09439" 11843 ENSMUSG00000021877.11 Arf4 14 VxPx cargo-targeting to cilium; COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic 0 High D3Z494 "Aldo-keto reductase family 1, member B10 (aldose reductase) OS=Mus musculus OX=10090 GN=Akr1b10 PE=1 SV=1" 0 3.902 4 1 4 1 288 32.7 7.01 1 1 1 1 1 1 1 1 398786.375 518366.6563 409883.6563 818929.125 1 1 1 1 Met-loss+Acetyl [N-Term] metabolic process mitochondrion catalytic activity Pf00248 ENSMUSG00000061758.13 6 Estrogen biosynthesis; Signaling by GPCR; Retinoid metabolism and transport 0 High Q99LB2 Dehydrogenase/reductase SDR family member 4 OS=Mus musculus OX=10090 GN=Dhrs4 PE=1 SV=3 0 8.229 12 4 4 4 279 29.9 9.38 4 4 5782530.125 4725423.875 6860475.75 10828088.75 4 3 3 4 cell organization and biogenesis;metabolic process membrane;mitochondrion;nucleus catalytic activity;protein binding "Pf00106, Pf08659, Pf13561" 28200 ENSMUSG00000022210.6 Dhrs4 14 RA biosynthesis pathway Retinol metabolism; Metabolic pathways; Peroxisome 0 High P58059 "28S ribosomal protein S21, mitochondrial OS=Mus musculus OX=10090 GN=Mrps21 PE=1 SV=1" 0 5.188 23 2 4 2 87 10.6 10.32 2 2 2 2 4525098 6898455 5441359 1 1 1 cell organization and biogenesis;metabolic process membrane;mitochondrion;ribosome RNA binding;structural molecule activity 66292 ENSMUSG00000054312.6 Mrps21 3 Ribosome 0 High Q8BWM0 Prostaglandin E synthase 2 OS=Mus musculus OX=10090 GN=Ptges2 PE=1 SV=3 0 14.219 15 4 4 4 384 43.3 9 4 4 304141.7188 16107261 1 2 cellular homeostasis;metabolic process;regulation of biological process;transport cytoplasm;cytosol;Golgi;membrane;mitochondrion;nucleus catalytic activity;DNA binding;protein binding "Pf00462, Pf13409, Pf13417, Pf14497" 96979 ENSMUSG00000026820.5 Ptges2 2 Neutrophil degranulation; Synthesis of Prostaglandins (PG) and Thromboxanes (TX) Metabolic pathways; Arachidonic acid metabolism 0 Medium P28481 Collagen alpha-1(II) chain OS=Mus musculus OX=10090 GN=Col2a1 PE=1 SV=2 0.016 1.485 2 1 4 1 1487 141.9 6.92 1 1 1 3 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;extracellular metal ion binding;protein binding;structural molecule activity "Pf00093, Pf01391, Pf01410, Pf14828" 12824 ENSMUSG00000022483.16 Col2a1 15 ECM proteoglycans; Collagen chain trimerization; Integrin cell surface interactions; MET activates PTK2 signaling; NCAM1 interactions; Collagen degradation; Non-integrin membrane-ECM interactions; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; Signaling by PDGF; Assembly of collagen fibrils and other multimeric structures Focal adhesion; Protein digestion and absorption; ECM-receptor interaction; PI3K-Akt signaling pathway 0 High A0A3B2WCC1 Mediator of ErbB2-driven cell motility 1 (Fragment) OS=Mus musculus OX=10090 GN=Memo1 PE=1 SV=1 0 6.073 20 2 4 2 107 11.8 9.1 2 4 1613369.75 2 0 High Q3TE00 Mediator of RNA polymerase II transcription subunit 15 OS=Mus musculus OX=10090 GN=Med15 PE=1 SV=1 0 10.29 6 4 4 4 766 83.7 9.36 3 1 3 1 3116528.188 4412212.25 3611842.875 3 2 2 metabolic process;regulation of biological process cytoplasm;nucleus Pf09606 94112 Med15 16 0 High D6RI22 Lactase-like protein OS=Mus musculus OX=10090 GN=Lctl PE=3 SV=1 0 6.902 11 3 4 3 235 26.6 6.73 3 4 23821119 3 metabolic process endoplasmic reticulum catalytic activity Pf00232 ENSMUSG00000032401.15 9 0 High B1AV77 Aldehyde dehydrogenase OS=Mus musculus OX=10090 GN=Aldh3a2 PE=1 SV=1 0 13.945 11 4 4 4 487 54.3 8.48 4 4 8237821.25 2 metabolic process;response to stimulus cytosol;endoplasmic reticulum;membrane;mitochondrion;nucleus catalytic activity Pf00171 11671 ENSMUSG00000010025.19 Aldh3a2 11 0 High A0A0G2JGX4 Sodium/potassium-transporting ATPase subunit alpha OS=Mus musculus OX=10090 GN=Atp1a3 PE=1 SV=1 0 11.877 4 4 4 4 1026 112.9 5.41 1 3 1 3 1756296.5 12990301 3 3 cellular homeostasis;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;Golgi;membrane;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding;transporter activity "Pf00122, Pf00689, Pf00690, Pf00702, Pf08282, Pf12710, Pf13246" 232975 ENSMUSG00000040907.15 Atp1a3 7 0 High Q3UNZ8 Quinone oxidoreductase-like protein 2 OS=Mus musculus OX=10090 GN=Cryzl2 PE=1 SV=1 0 17.513 17 4 4 4 350 37.8 8.9 4 4 342321.4375 4792208 1 1 metabolic process mitochondrion catalytic activity "Pf00107, Pf08240, Pf13602" 226527 ENSMUSG00000033488.11 BC026585; Cryzl2 1 0 High Q3USZ8 Divergent protein kinase domain 2A OS=Mus musculus OX=10090 GN=Dipk2a PE=1 SV=2 0 14.756 12 4 4 4 430 49.4 8.63 4 4 226488.2344 1493662.125 15365529.5 1 1 3 cell proliferation;regulation of biological process extracellular;Golgi;membrane Pf12260 68861 ENSMUSG00000045414.7 1190002N15Rik 9 0 High A0A0R4J0X2 5-aminolevulinate synthase OS=Mus musculus OX=10090 GN=Alas1 PE=1 SV=1 0 11.306 12 4 4 4 641 70.9 8.53 4 4 4428269.313 3 metabolic process cytosol;mitochondrion;organelle lumen catalytic activity;protein binding "Pf00155, Pf01053, Pf09029" 11655 ENSMUSG00000032786.16 Alas1 9 0 High P62900 60S ribosomal protein L31 OS=Mus musculus OX=10090 GN=Rpl31 PE=1 SV=1 0.001 3.566 7 1 4 1 125 14.5 10.54 1 1 1 1 1 1 1 1 2823317 9114339 8699060 12533205 1 1 1 1 metabolic process membrane;ribosome protein binding;RNA binding;structural molecule activity Pf01198 114641 ENSMUSG00000073702.11 Rpl31 1 Ribosome 0 High Q91V77 Protein S100 OS=Mus musculus OX=10090 GN=S100a1 PE=1 SV=1 0 5.924 23 1 4 1 94 10.5 4.59 1 1 1 1 1 1 1 1 243473.7656 690387.75 528167.625 6762385.5 1 1 1 1 Met-loss+Acetyl [N-Term] regulation of biological process cytoplasm;endoplasmic reticulum;nucleus metal ion binding;protein binding Pf01023 20193 ENSMUSG00000044080.9 S100a1 3 Regulation of TLR by endogenous ligand 0 High E9QAQ3 Rho GTPase-activating protein 26 OS=Mus musculus OX=10090 GN=Arhgap26 PE=1 SV=1 0 10.813 6 4 4 4 759 85.9 6.74 2 2 2 2 4108037 4190679.25 1 1 cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytoskeleton enzyme regulator activity;protein binding "Pf00018, Pf00169, Pf00620, Pf03114, Pf07653, Pf08397, Pf14604" 71302 ENSMUSG00000036452.17 Arhgap26 18 0 High A0A075B5U0 Immunoglobulin heavy variable V1-12 OS=Mus musculus OX=10090 GN=Ighv1-12 PE=4 SV=1 0 5.807 24 2 4 1 98 10.8 9.07 1 1 1 1 1 1 1 1 1406322.25 3140096 1 1 Pf07686 ENSMUSG00000095416.6 12 0 High P61514 60S ribosomal protein L37a OS=Mus musculus OX=10090 GN=Rpl37a PE=1 SV=2 0 6.862 38 3 4 3 92 10.3 10.43 1 1 1 1 1 1 1 1 943256.9375 1434230.875 1 1 metabolic process nucleus;ribosome metal ion binding;RNA binding;structural molecule activity Pf01780 19981 ENSMUSG00000046330.10 Rpl37a 1 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High K3W4Q8 Basigin OS=Mus musculus OX=10090 GN=Bsg PE=1 SV=1 0 9.13 14 3 4 3 218 24.1 5.36 3 4 484366.7188 1877626.438 1107121.5 25096012.5 1 2 1 3 cell organization and biogenesis membrane;mitochondrion protein binding "Pf00047, Pf07679, Pf13927" 12215 ENSMUSG00000023175.15 Bsg 10 0 High Q9JMG2 C1GALT1-specific chaperone 1 OS=Mus musculus OX=10090 GN=C1galt1c1 PE=2 SV=1 0 13.379 9 2 4 2 316 36 6.74 2 4 18503117 2 cell organization and biogenesis;metabolic process;regulation of biological process membrane catalytic activity 59048 ENSMUSG00000048970.9 C1galt1c1 X O-linked glycosylation of mucins Metabolic pathways; Mucin type O-glycan biosynthesis 0 High Q5HZI9 Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51 OS=Mus musculus OX=10090 GN=Slc25a51 PE=1 SV=1 0 11.223 12 3 4 3 298 33.7 9.66 3 4 transport membrane;mitochondrion transporter activity Pf00153 230125 ENSMUSG00000045973.18 Mcart1; Slc25a51 4 0 High Q8R0N6 "Hydroxyacid-oxoacid transhydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Adhfe1 PE=1 SV=2" 0 13.169 9 2 4 2 465 49.9 7.58 2 1 1 2 1 1 7462339.75 8150703.25 8681122 2 2 1 metabolic process;transport cytosol;mitochondrion catalytic activity;metal ion binding "Pf00465, Pf13685" 76187 ENSMUSG00000025911.14 Adhfe1 1 Interconversion of 2-oxoglutarate and 2-hydroxyglutarate 0 High Q9CQQ7 "ATP synthase F(0) complex subunit B1, mitochondrial OS=Mus musculus OX=10090 GN=Atp5pb PE=1 SV=1" 0 5.734 12 3 4 3 256 28.9 9.06 3 4 2347498.219 2996011.75 17535102.75 2 1 3 metabolic process;transport membrane;mitochondrion;nucleus catalytic activity;transporter activity Pf05405 11950 ENSMUSG00000000563.17 Atp5f1 3 Cristae formation; Formation of ATP by chemiosmotic coupling Metabolic pathways; Huntington's disease; Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High A0A075B5L7 Immunoglobulin kappa variable 4-80 (Fragment) OS=Mus musculus OX=10090 GN=Igkv4-80 PE=4 SV=2 0.001 3.616 14 1 4 1 116 12.6 5.15 1 1 1 1 1 2 8283213 14137868 10384441 1 1 1 response to stimulus "Pf00047, Pf07679, Pf07686" 545848 ENSMUSG00000076540.3 Igkv4-80 6 0 High A2AJ88 Patatin-like phospholipase domain-containing protein 7 OS=Mus musculus OX=10090 GN=Pnpla7 PE=1 SV=1 0 13.344 3 3 4 3 1352 150.4 6.92 3 1 3 1 5991936.75 5153933.25 2 2 metabolic process endoplasmic reticulum;membrane;mitochondrion;nucleus;vacuole catalytic activity "Pf00027, Pf01734" 241274 ENSMUSG00000036833.16 Pnpla7 2 Glycerophospholipid metabolism 0 High Q9CZJ2 Heat shock 70 kDa protein 12B OS=Mus musculus OX=10090 GN=Hspa12b PE=1 SV=1 0 6.771 9 3 3 3 685 76.1 8.47 3 3 351387.7813 2923051.5 1 1 Acetyl [N-Term] nucleotide binding 72630 ENSMUSG00000074793.10 Hspa12b 2 0 High P09411 Phosphoglycerate kinase 1 OS=Mus musculus OX=10090 GN=Pgk1 PE=1 SV=4 0 8.678 12 3 3 3 417 44.5 7.9 3 3 2896115.625 3 cell differentiation;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane catalytic activity;nucleotide binding Pf00162 18655 ENSMUSG00000062070.12 Pgk1 X Gluconeogenesis; Glycolysis Metabolic pathways; Biosynthesis of amino acids; Glycolysis / Gluconeogenesis; HIF-1 signaling pathway; Carbon metabolism 0 High A0A0N4SV00 T-complex protein 1 subunit eta OS=Mus musculus OX=10090 GN=Cct7 PE=1 SV=1 0 3.952 5 3 3 3 502 55 7.83 2 1 2 1 5487603.156 2146587.281 6430527.438 11498551 3 2 2 1 Acetyl [N-Term] metabolic process;transport cytoplasm;mitochondrion nucleotide binding;protein binding Pf00118 ENSMUSG00000030007.8 6 0 High P01819 Ig heavy chain V region MOPC 141 OS=Mus musculus OX=10090 PE=4 SV=1 0.003 3.225 8 1 3 1 144 15.7 8.43 1 1 1 1 1 1 4490899 11303219 9906012 3811226 1 1 1 1 Pf07686 0 High Q8BKT7 THO complex subunit 5 homolog OS=Mus musculus OX=10090 GN=Thoc5 PE=1 SV=2 0 11.806 7 3 3 3 683 78.6 7.12 3 3 206122 2223868.5 3321852 1 1 1 cell differentiation;cell division;cell organization and biogenesis;metabolic process;regulation of biological process;transport chromosome;cytoplasm;nucleus protein binding;RNA binding Pf09766 107829 Thoc5 11 RNA transport 0 High A0A0R4J0Q4 Lysyl oxidase homolog OS=Mus musculus OX=10090 GN=Loxl1 PE=1 SV=1 0 9.741 7 3 3 3 607 66.5 7.33 3 3 1417846.75 20422852.5 1 2 metabolic process;response to stimulus cytoplasm;extracellular catalytic activity;metal ion binding;protein binding Pf01186 16949 ENSMUSG00000032334.10 Loxl1 9 Elastic fibre formation; Crosslinking of collagen fibrils 0 High Q9DBB8 "Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase OS=Mus musculus OX=10090 GN=Dhdh PE=1 SV=1" 0 18.255 10 3 3 3 333 36.3 6.44 3 3 11861296.25 3 metabolic process catalytic activity "Pf01408, Pf02894, Pf03807" 71755 ENSMUSG00000011382.8 Dhdh 7 Pentose and glucuronate interconversions; Metabolism of xenobiotics by cytochrome P450 0 High H3BL49 CCT-theta OS=Mus musculus OX=10090 GN=Cct8 PE=1 SV=1 0 7.685 7 3 3 3 489 53 5.5 3 3 1669562.188 3 cell organization and biogenesis;metabolic process;transport nucleotide binding;protein binding Pf00118 ENSMUSG00000025613.13 16 0 High Q5SWW4 Mediator of RNA polymerase II transcription subunit 13 OS=Mus musculus OX=10090 GN=Med13 PE=1 SV=1 0 10.091 3 3 3 3 2171 238.4 5.67 2 1 2 1 360968.9375 1 Met-loss+Acetyl [N-Term] metabolic process;regulation of biological process;response to stimulus membrane;nucleus protein binding;receptor activity "Pf06333, Pf11597" 327987 ENSMUSG00000034297.14 Med13 11 Generic Transcription Pathway; Mus musculus biological processes; Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes Thyroid hormone signaling pathway 0 High Q925N0 Sideroflexin-5 OS=Mus musculus OX=10090 GN=Sfxn5 PE=1 SV=2 0 10.157 11 3 3 3 342 37.3 9.44 3 3 transport membrane;mitochondrion transporter activity Pf03820 94282 ENSMUSG00000033720.12 Sfxn5 6 0 High Q9Z1Z2 Serine-threonine kinase receptor-associated protein OS=Mus musculus OX=10090 GN=Strap PE=1 SV=2 0 11.185 12 3 3 3 350 38.4 5.12 3 3 3373349.75 1 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;cytosol;nucleus catalytic activity;protein binding;RNA binding Pf00400 20901 ENSMUSG00000030224.10 Strap 6 Downregulation of TGF-beta receptor signaling RNA transport 0 Low Q6IE21 OTU domain-containing protein 6A OS=Mus musculus OX=10090 GN=Otud6a PE=1 SV=1 0.053 1.008 3 1 3 1 290 33.7 7.34 1 3 21620118 1 metabolic process catalytic activity "Pf02338, Pf10275" 408193 ENSMUSG00000051582.2 Otud6a X 0 High O35295 Transcriptional activator protein Pur-beta OS=Mus musculus OX=10090 GN=Purb PE=1 SV=3 0 7.635 9 3 3 3 324 33.9 5.43 3 3 2674128.438 946558.6875 3918666.125 4566294.25 3 1 2 2 cell death;cell differentiation;cell proliferation;metabolic process;regulation of biological process nucleus DNA binding;protein binding;RNA binding;translation regulator activity Pf04845 19291 ENSMUSG00000094483.2 Purb 11 0 High E9Q852 Afadin OS=Mus musculus OX=10090 GN=Afdn PE=1 SV=2 0 7.213 3 3 3 3 1805 204.4 6.24 1 1 1 1 1 1 326684.0625 5165888.5 1 1 cell differentiation;cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm protein binding "Pf00498, Pf00595, Pf00788, Pf01843" ENSMUSG00000068036.14 17 0 High Q9DC71 "28S ribosomal protein S15, mitochondrial OS=Mus musculus OX=10090 GN=Mrps15 PE=1 SV=2" 0.004 2.365 3 1 3 1 258 29.4 10.13 1 1 1 1 1 1 472164.1875 4385349.5 4771590 4467019 1 1 1 1 cell organization and biogenesis;metabolic process mitochondrion;nucleus;ribosome RNA binding;structural molecule activity Pf00312 66407 ENSMUSG00000028861.13 Mrps15 4 Mitochondrial translation termination; Mitochondrial translation elongation Ribosome 0 High A0A2R8VHF9 Myosin-11 OS=Mus musculus OX=10090 GN=Myh11 PE=1 SV=1 0 9.114 2 3 3 3 1938 223.2 5.5 3 3 1792601.125 2 0 High Q9Z2A7 Diacylglycerol O-acyltransferase 1 OS=Mus musculus OX=10090 GN=Dgat1 PE=1 SV=1 0 14.988 11 3 3 3 498 56.8 9.39 3 3 12210759 2 cell organization and biogenesis;metabolic process;regulation of biological process;transport endoplasmic reticulum;membrane catalytic activity "Pf03062, Pf13813" 13350 ENSMUSG00000022555.11 Dgat1 15 Triglyceride biosynthesis; Neutrophil degranulation; Acyl chain remodeling of DAG and TAG Retinol metabolism; Fat digestion and absorption; Metabolic pathways; Glycerolipid metabolism 0 High Q91VD9 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Mus musculus OX=10090 GN=Ndufs1 PE=1 SV=2" 0.001 3.353 3 2 3 2 727 79.7 5.72 2 3 785194.3125 1011619.75 2024600.875 1 1 1 cell organization and biogenesis;metabolic process;transport membrane;mitochondrion catalytic activity;metal ion binding "Pf00111, Pf00384, Pf09326, Pf10588, Pf13510" 227197 ENSMUSG00000025968.16 Ndufs1 1 Complex I biogenesis Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High Q9DC61 Mitochondrial-processing peptidase subunit alpha OS=Mus musculus OX=10090 GN=Pmpca PE=1 SV=1 0 5.812 3 1 3 1 524 58.2 6.83 1 1 1 1 1 1 51723.10938 183050.1719 753828.875 1 1 1 metabolic process membrane;mitochondrion;organelle lumen catalytic activity;metal ion binding "Pf00675, Pf05193" 66865 ENSMUSG00000026926.14 Pmpca 2 Processing of SMDT1 0 High Q9EP72 ER membrane protein complex subunit 7 OS=Mus musculus OX=10090 GN=Emc7 PE=1 SV=1 0 12.628 22 3 3 3 241 26.3 9.23 3 3 12453122 2 membrane Pf09430 73024 ENSMUSG00000055943.5 Emc7 2 0 High Q9DBH5 Vesicular integral-membrane protein VIP36 OS=Mus musculus OX=10090 GN=Lman2 PE=1 SV=2 0 4.308 5 2 3 2 358 40.4 6.95 2 3 199061.3906 13074265.5 1 2 regulation of biological process;transport cell surface;Golgi;membrane metal ion binding;protein binding Pf03388 66890 ENSMUSG00000021484.7 Lman2 13 Protein processing in endoplasmic reticulum 0 High P17563 Methanethiol oxidase OS=Mus musculus OX=10090 GN=Selenbp1 PE=1 SV=2 0 5.879 9 3 3 3 472 52.5 6.29 3 3 1058458.375 1 cell differentiation;transport cytoplasm;cytosol;membrane;nucleus "Pf05694, Pf10282" 20341 ENSMUSG00000068874.13 Selenbp1 3 0 High Q6ZWQ7 Signal peptidase complex subunit 3 OS=Mus musculus OX=10090 GN=Spcs3 PE=1 SV=1 0 6.373 12 2 3 2 180 20.3 8.62 2 3 39189656 1 metabolic process endoplasmic reticulum;membrane catalytic activity Pf04573 76687 ENSMUSG00000054408.9 Spcs3 8 "Synthesis, secretion, and deacylation of Ghrelin" Protein export 0 High P62274 40S ribosomal protein S29 OS=Mus musculus OX=10090 GN=Rps29 PE=1 SV=2 0 4.906 34 2 3 2 56 6.7 10.13 1 2 1 2 566528.5625 2190877.5 5061278 1 1 1 Met-loss [N-Term] metabolic process;regulation of biological process ribosome metal ion binding;structural molecule activity Pf00253 20090 ENSMUSG00000034892.8 Rps29 12 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High P17665 "Cytochrome c oxidase subunit 7C, mitochondrial OS=Mus musculus OX=10090 GN=Cox7c PE=1 SV=1" 0.004 2.558 14 1 3 1 63 7.3 11 1 1 1 1 1 1 1147487 3364696 5860933.5 1 1 1 metabolic process;transport membrane;mitochondrion catalytic activity;transporter activity Pf02935 12867; 654359; 102642884 ENSMUSG00000017778.14 Cox7c; Gm12338; LOC100048613; LOC102642884 13; 11; 2 Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 Medium Q9QZZ4 Unconventional myosin-XV OS=Mus musculus OX=10090 GN=Myo15a PE=1 SV=2 0.017 1.363 0 1 3 1 3511 395.4 9.16 1 1 1 2 3935277 12584822 13408466 15764587 1 1 1 1 response to stimulus cytoplasm;cytoskeleton catalytic activity;motor activity;nucleotide binding;protein binding "Pf00063, Pf00373, Pf00784, Pf07653" 17910 ENSMUSG00000042678.16 Myo15 11 0 High A0A0A0MQM2 Phosphoinositide phospholipase C OS=Mus musculus OX=10090 GN=Plch1 PE=1 SV=1 0.01 1.773 1 1 3 1 1073 122.5 7.72 1 3 310678107 1 metabolic process;regulation of biological process;response to stimulus catalytic activity;metal ion binding;protein binding;signal transducer activity "Pf00036, Pf00168, Pf00387, Pf00388, Pf09279, Pf13499, Pf14788" ENSMUSG00000036834.16 3 0 High P56392 "Cytochrome c oxidase subunit 7A1, mitochondrial OS=Mus musculus OX=10090 GN=Cox7a1 PE=1 SV=1" 0.003 2.997 16 1 3 1 80 9 9.79 1 1 1 1 1 1 496256.3125 2952841 3906774.75 10275064 1 1 1 1 metabolic process;transport membrane;mitochondrion catalytic activity;transporter activity Pf02238 12865 ENSMUSG00000074218.3 Cox7a1 7 Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 High P28654 Decorin OS=Mus musculus OX=10090 GN=Dcn PE=1 SV=1 0.001 3.368 3 1 3 1 354 39.8 8.68 1 3 2062475.25 1215205.375 2358056.75 1 1 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;extracellular enzyme regulator activity;protein binding;RNA binding "Pf01462, Pf12799, Pf13306, Pf13855" 13179 ENSMUSG00000019929.16 Dcn 10 A tetrasaccharide linker sequence is required for GAG synthesis; ECM proteoglycans; CS/DS degradation; Degradation of the extracellular matrix; Dermatan sulfate biosynthesis; Chondroitin sulfate biosynthesis Proteoglycans in cancer; TGF-beta signaling pathway 0 High P97450 "ATP synthase-coupling factor 6, mitochondrial OS=Mus musculus OX=10090 GN=Atp5pf PE=1 SV=1" 0 12.35 44 3 3 3 108 12.5 9.36 3 3 6441704.5 1 metabolic process;transport membrane;mitochondrion catalytic activity;transporter activity Pf05511 11957 ENSMUSG00000022890.13 Atp5j 16 Cristae formation; Formation of ATP by chemiosmotic coupling Metabolic pathways; Huntington's disease; Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High Q9DBN5 "Lon protease homolog 2, peroxisomal OS=Mus musculus OX=10090 GN=Lonp2 PE=1 SV=1" 0 11.275 5 3 3 3 852 94.5 7.23 3 3 261711.8125 8083212 1 2 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;membrane;nucleus;organelle lumen catalytic activity;nucleotide binding;protein binding "Pf00004, Pf01202, Pf02190, Pf04124, Pf05362, Pf07726, Pf07728, Pf13191, Pf13541" 66887 ENSMUSG00000047866.18 Lonp2 8 0 High Q8C2Q3 RNA-binding protein 14 OS=Mus musculus OX=10090 GN=Rbm14 PE=1 SV=1 0 12.684 7 2 3 2 669 69.4 9.67 2 3 77935.21875 107780.3516 223098.3906 5658067.438 1 1 1 2 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus RNA binding "Pf00076, Pf13893, Pf14259" 56275 ENSMUSG00000006456.10 Rbm14 19 RUNX2 regulates bone development 0 High G3UZI2 Heterogeneous nuclear ribonucleoprotein Q OS=Mus musculus OX=10090 GN=Syncrip PE=1 SV=1 0 6.514 4 2 3 2 527 58.7 7.56 1 2 1 2 888118.7188 720121.6875 3159422.5 1575859.25 2 1 2 1 RNA binding "Pf00076, Pf13893, Pf14259" ENSMUSG00000032423.12 9 0 High Q80U72 Protein scribble homolog OS=Mus musculus OX=10090 GN=Scrib PE=1 SV=2 0 5.405 2 3 3 3 1612 174 5.12 3 3 cell death;cell differentiation;cell organization and biogenesis;cell proliferation;cellular component movement;development;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;membrane catalytic activity;protein binding "Pf00595, Pf12799, Pf13180, Pf13855, Pf14580" 105782 ENSMUSG00000022568.16 Scrib 15 Hippo signaling pathway; Viral carcinogenesis 0 High Q7TPH6 E3 ubiquitin-protein ligase MYCBP2 OS=Mus musculus OX=10090 GN=Mycbp2 PE=1 SV=3 0 6.315 1 3 3 3 4749 520.9 7.09 3 3 744892.5781 353797.2188 3 1 0 Medium A2A432 Cullin-4B OS=Mus musculus OX=10090 GN=Cul4b PE=1 SV=1 0.01 1.684 1 1 3 1 970 110.6 8.37 1 1 1 2 14187195.5 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytosol;nucleus catalytic activity;DNA binding;protein binding "Pf00888, Pf10557" 72584 ENSMUSG00000031095.15 Cul4b X Dual incision in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; DNA Damage Recognition in GG-NER; Formation of Incision Complex in GG-NER; Neddylation; Formation of TC-NER Pre-Incision Complex; Gap-filling DNA repair synthesis and ligation in TC-NER Ubiquitin mediated proteolysis; Nucleotide excision repair 0 High Q9Z315 U4/U6.U5 tri-snRNP-associated protein 1 OS=Mus musculus OX=10090 GN=Sart1 PE=1 SV=1 0 12.364 5 3 3 3 806 90.8 5.82 3 3 1961175.125 1 cell organization and biogenesis;metabolic process;regulation of biological process Golgi;nucleus;spliceosomal complex RNA binding Pf03343 20227 ENSMUSG00000039148.4 Sart1 19 mRNA Splicing - Major Pathway Spliceosome 0 High Q9R0E2 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 OS=Mus musculus OX=10090 GN=Plod1 PE=1 SV=1" 0 5.884 3 3 3 2 728 83.5 6.54 3 3 6316156 1 metabolic process;response to stimulus endoplasmic reticulum;membrane catalytic activity;metal ion binding;protein binding Pf03171 18822 ENSMUSG00000019055.15 Plod1 4 Collagen biosynthesis and modifying enzymes Lysine degradation 0 High A0A2R8VK72 Methyltransferase-like 7A1 OS=Mus musculus OX=10090 GN=Mettl7a1 PE=1 SV=1 0 12.119 17 2 3 2 193 22.5 8 2 3 12838117 2 0 High Q61555 Fibrillin-2 OS=Mus musculus OX=10090 GN=Fbn2 PE=1 SV=2 0.001 3.631 1 2 3 1 2907 313.6 4.84 2 3 regulation of biological process cell surface;extracellular;membrane metal ion binding;protein binding;structural molecule activity "Pf00028, Pf00683, Pf06247, Pf07645, Pf12662, Pf12947, Pf14670" 14119 ENSMUSG00000024598.8 Fbn2 18 Molecules associated with elastic fibres; Degradation of the extracellular matrix 0 High A0A0G2JGD2 Protein S100-A4 (Fragment) OS=Mus musculus OX=10090 GN=S100a4 PE=1 SV=1 0 5.493 23 1 3 1 78 9.1 5.21 1 1 1 1 1 1 99882.38281 537751.6875 827333.5625 6565765.5 1 1 1 1 Met-loss+Acetyl [N-Term] metal ion binding;protein binding Pf01023 ENSMUSG00000001020.8 3 0 High A3KGW5 Inactive glycosyltransferase 25 family member 3 OS=Mus musculus OX=10090 GN=Cercam PE=3 SV=1 0 8.282 5 3 3 3 592 67.6 6.76 3 3 endoplasmic reticulum;organelle lumen Pf01755 99151 ENSMUSG00000039787.13 Cercam 2 0 High A0A075B5N5 Immunoglobulin kappa variable 8-26 (Fragment) OS=Mus musculus OX=10090 GN=Igkv8-26 PE=4 SV=7 0.003 2.735 7 1 3 1 123 13.8 6.9 1 1 1 2 694394.75 7774304 1 1 response to stimulus "Pf07679, Pf07686" ENSMUSG00000076581.1 6 0 High Q5U4D9 THO complex subunit 6 homolog OS=Mus musculus OX=10090 GN=Thoc6 PE=1 SV=1 0 10.916 13 3 3 3 341 37.3 7.12 1 2 1 2 Acetyl [N-Term] cell death;development;metabolic process;regulation of biological process;transport nucleus protein binding;RNA binding Pf00400 386612 ENSMUSG00000041319.13 Thoc6 17 mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript RNA transport 0 High Q9QY76 Vesicle-associated membrane protein-associated protein B OS=Mus musculus OX=10090 GN=Vapb PE=1 SV=3 0 9.62 13 3 3 3 243 26.9 7.78 3 3 11217010 2 cell organization and biogenesis;cellular homeostasis;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;Golgi;membrane protein binding Pf00635 56491 Vapb 2 0 High Q9JI95 CPN10-like protein OS=Mus musculus OX=10090 GN=Hspe1-rs1 PE=3 SV=1 0 3.733 20 2 3 2 102 11 8.92 1 2 1 2 2731372.188 5035725.25 1439610.625 3876618 2 2 1 1 metabolic process cytoplasm Pf00166 628438 Hspe1-rs1 18 0 High Q78IK2 "ATP synthase membrane subunit K, mitochondrial OS=Mus musculus OX=10090 GN=Atp5mk PE=1 SV=1" 0 10.543 29 2 3 2 58 6.4 9.83 2 3 168501.3906 1360753.75 18445593 1 1 2 Met-loss [N-Term] membrane;mitochondrion Pf14960 66477; 102642507 ENSMUSG00000071528.3 Usmg5; LOC100504912; LOC102642507 19; 4 0 High P17225 Polypyrimidine tract-binding protein 1 OS=Mus musculus OX=10090 GN=Ptbp1 PE=1 SV=2 0 6.034 6 3 3 2 527 56.4 8.34 1 2 1 2 2320200.688 2718405.5 5151797.125 4541446 3 2 3 1 metabolic process;regulation of biological process cytoplasm;membrane;nucleus catalytic activity;DNA binding;protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 19205 Ptbp1 10 1 Medium G3X9Y4 Rho-related GTP-binding protein RhoD OS=Mus musculus OX=10090 GN=Rhod PE=1 SV=1 0.017 1.359 4 1 3 1 200 22.3 9.04 1 1 1 1 1 1 760785.125 4068285.75 8036976.5 5692681 1 1 1 1 cell organization and biogenesis;regulation of biological process;response to stimulus;transport endosome;membrane catalytic activity;nucleotide binding;protein binding "Pf00025, Pf00071, Pf04670, Pf08477" 11854 ENSMUSG00000041845.10 Rhod 19 0 High Q8C7E7 Starch-binding domain-containing protein 1 OS=Mus musculus OX=10090 GN=Stbd1 PE=1 SV=1 0 6.888 8 3 3 3 338 36.1 5.99 3 3 2927240.125 3 metabolic process;transport cytosol;endoplasmic reticulum;membrane protein binding Pf00686 52331 ENSMUSG00000047963.7 Stbd1 5 Neutrophil degranulation 0 High A0A075B5K9 Immunoglobulin kappa variable 12-98 OS=Mus musculus OX=10090 GN=Igkv12-98 PE=4 SV=7 0 6.634 25 2 3 2 114 12.3 7.83 2 1 2 1 3409927.5 2 Pf07686 ENSMUSG00000076526.6 6 0 High Q9DC70 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial OS=Mus musculus OX=10090 GN=Ndufs7 PE=1 SV=1" 0 11.055 18 2 3 2 224 24.7 9.92 1 1 1 1 1 1 206782.8594 2598084.75 1 1 cell organization and biogenesis;metabolic process;transport membrane;mitochondrion catalytic activity;metal ion binding;protein binding Pf01058 75406 ENSMUSG00000020153.14 Ndufs7 10 Complex I biogenesis Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High A0A0A6YW37 Immunoglobulin heavy variable V1-9 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-9 PE=4 SV=1 0 11.893 21 1 3 1 117 13 7.28 1 1 2 1 8735313 2344262 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000094694.6 12 0 High Q61646 Haptoglobin OS=Mus musculus OX=10090 GN=Hp PE=1 SV=1 0 7.42 8 3 3 3 347 38.7 6.29 3 3 12369748 2 defense response;metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;extracellular;Golgi antioxidant activity;catalytic activity;protein binding "Pf00084, Pf00089" 15439 ENSMUSG00000031722.10 Hp 8 Neutrophil degranulation; Scavenging of heme from plasma 0 High F6V6T4 Transmembrane emp24 domain-containing protein 2 (Fragment) OS=Mus musculus OX=10090 GN=Tmed2 PE=1 SV=1 0 9.047 20 2 3 2 176 20 9.07 2 3 8844771 1 regulation of biological process;transport membrane Pf01105 ENSMUSG00000029390.13 5 0 High Q6P8J7 "Creatine kinase S-type, mitochondrial OS=Mus musculus OX=10090 GN=Ckmt2 PE=1 SV=1" 0.003 2.975 8 2 3 2 419 47.4 8.4 2 3 1360016.25 1 metabolic process membrane;mitochondrion catalytic activity;nucleotide binding "Pf00217, Pf02807" 76722 ENSMUSG00000021622.3 Ckmt2 13 Creatine metabolism Arginine and proline metabolism; Metabolic pathways 0 High F6Q269 JmjC domain-containing protein 8 OS=Mus musculus OX=10090 GN=Jmjd8 PE=1 SV=2 0 8.09 13 2 3 2 186 20.9 7.3 2 3 34881714 2 0 High Q9CQB4 Cytochrome b-c1 complex subunit 7 OS=Mus musculus OX=10090 GN=Uqcrb PE=1 SV=1 0 4.056 15 2 3 2 111 13.6 9.11 1 2 1 2 1484394.75 5203018.125 1027318.125 4373564.75 2 2 1 2 cell organization and biogenesis;metabolic process;transport membrane;mitochondrion catalytic activity;transporter activity Pf02271 67530 ENSMUSG00000021520.4 Uqcrb 13 Respiratory electron transport Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 High Q9D952 Envoplakin OS=Mus musculus OX=10090 GN=Evpl PE=1 SV=3 0.006 2.147 1 1 3 1 2035 231.9 6.6 1 1 1 1 1 1 98900046.63 72569491.5 62995094.5 54848632 1 1 1 1 cell differentiation;metabolic process cytoplasm;cytoskeleton;cytosol protein binding;structural molecule activity Pf00681 14027 ENSMUSG00000034282.3 Evpl 11 Formation of the cornified envelope 0 High P35487 "Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial OS=Mus musculus OX=10090 GN=Pdha2 PE=1 SV=1" 0 6.697 10 2 3 2 391 43.4 8.5 2 1 2 1 9206668 10270746 10397604 31978484 1 1 1 1 metabolic process mitochondrion;organelle lumen catalytic activity Pf00676 18598 ENSMUSG00000047674.2 Pdha2 3 Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Glyoxylate metabolism and glycine degradation Pyruvate metabolism; Citrate cycle (TCA cycle); Metabolic pathways; Glycolysis / Gluconeogenesis; HIF-1 signaling pathway; Carbon metabolism; Central carbon metabolism in cancer; Glucagon signaling pathway 0 High Q9D8T7 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Mus musculus OX=10090 GN=Slirp PE=1 SV=2" 0 6.364 25 3 3 3 112 12.6 9.82 3 3 678698.75 5568949 1 1 cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process cytoplasm;mitochondrion;nucleus RNA binding "Pf00076, Pf05172, Pf13893, Pf14259" 380773 ENSMUSG00000021040.15 Slirp 12 0 High O89017 Legumain OS=Mus musculus OX=10090 GN=Lgmn PE=1 SV=1 0 11.525 9 3 3 3 435 49.3 6.39 3 3 4380540 1 metabolic process;regulation of biological process;response to stimulus endosome;vacuole catalytic activity Pf01650 19141 ENSMUSG00000021190.14 Lgmn 12 MHC class II antigen presentation; Vitamin D (calciferol) metabolism; Trafficking and processing of endosomal TLR Lysosome; Antigen processing and presentation 0 High Q3UJB0 "Splicing factor 3b, subunit 2 OS=Mus musculus OX=10090 GN=Sf3b2 PE=1 SV=1" 0 8.563 4 3 3 3 878 98.1 5.62 3 3 409482.7969 1212105.875 7934028.5 1575828.875 2 1 3 1 metabolic process nucleus;spliceosomal complex protein binding;RNA binding "Pf02037, Pf04037, Pf04046" 319322 ENSMUSG00000024853.9 Sf3b2 19 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway Spliceosome 0 High Q8BMS4 "Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Mus musculus OX=10090 GN=Coq3 PE=1 SV=1" 0 10.798 12 3 3 3 370 40.9 7.96 3 3 288199.5 9844396 1 1 metabolic process;regulation of biological process membrane;mitochondrion catalytic activity "Pf01209, Pf02353, Pf06325, Pf08003, Pf08241, Pf08242, Pf09445, Pf12847, Pf13489, Pf13649, Pf13659, Pf13847" 230027 ENSMUSG00000028247.2 Coq3 4 Ubiquinol biosynthesis Ubiquinone and other terpenoid-quinone biosynthesis; Metabolic pathways 0 High P42208 Septin-2 OS=Mus musculus OX=10090 GN=Septin2 PE=1 SV=2 0 7.246 9 3 3 3 361 41.5 6.55 3 3 3578455.563 1895667.75 3 1 cell differentiation;cell division;cell organization and biogenesis;regulation of biological process;response to stimulus cell surface;chromosome;cytoplasm;cytoskeleton;cytosol;membrane;nucleus catalytic activity;enzyme regulator activity;nucleotide binding;protein binding;structural molecule activity "Pf00071, Pf00735, Pf01926" 18000 ENSMUSG00000026276.18; ENSMUSG00000112508.1 Sept2 1 Anchoring of the basal body to the plasma membrane Bacterial invasion of epithelial cells 0 High E9Q7G1 Transmembrane p24-trafficking protein 7 OS=Mus musculus OX=10090 GN=Tmed7 PE=1 SV=1 0 10.215 22 3 3 3 188 21.3 6.2 3 3 3322273.5 2339194.5 3069303 1 1 1 transport endoplasmic reticulum;Golgi;membrane Pf01105 ENSMUSG00000033184.14 18 COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic 0 High A0A087WRA1 Actin-like protein 3 (Fragment) OS=Mus musculus OX=10090 GN=Actr3 PE=1 SV=1 0.003 3.271 12 2 3 2 216 24.1 5 1 1 1 1 1 1 95462.82031 170011.125 154497.5 1111150.25 1 1 1 1 cell organization and biogenesis;regulation of biological process nucleotide binding Pf00022 ENSMUSG00000026341.16 1 0 High A2BDX2 Dolichol-phosphate mannosyltransferase subunit 1 OS=Mus musculus OX=10090 GN=Dpm1 PE=1 SV=1 0 11.426 16 3 3 3 208 23.4 9.31 3 3 16169920 2 metabolic process endoplasmic reticulum;membrane;nucleus catalytic activity "Pf00535, Pf10111, Pf13641, Pf13704, Pf13712" 13480 ENSMUSG00000078919.10 Dpm1 2 0 High Q9CQE3 "28S ribosomal protein S17, mitochondrial OS=Mus musculus OX=10090 GN=Mrps17 PE=1 SV=1" 0 4.272 8 1 3 1 120 13.4 9.89 1 1 1 1 1 1 291629.2813 2871599.75 3886902 5617443.5 1 1 1 1 cell organization and biogenesis;metabolic process mitochondrion;ribosome RNA binding;structural molecule activity Pf00366 66258 ENSMUSG00000034211.14 Mrps17 5 Mitochondrial translation termination; Mitochondrial translation elongation Ribosome 0 High Q99P87 Resistin OS=Mus musculus OX=10090 GN=Retn PE=1 SV=1 0 4.452 17 2 3 2 114 12.5 7.75 1 2 1 2 3531292.875 10974151 2 2 cell differentiation;regulation of biological process;response to stimulus extracellular;nucleus protein binding Pf06954 57264 ENSMUSG00000012705.16 Retn 8 Neutrophil degranulation 0 High A0A0G2JG10 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Mus musculus OX=10090 GN=Dhx15 PE=1 SV=1 0 5.24 3 2 3 2 608 68.5 6.8 1 1 1 1 1 1 743768.625 2617413.25 10657118.25 4823945.875 2 2 2 2 catalytic activity;nucleotide binding "Pf00270, Pf00271, Pf04408, Pf13401" ENSMUSG00000029169.11 5 0 High P23242 Gap junction alpha-1 protein OS=Mus musculus OX=10090 GN=Gja1 PE=1 SV=2 0 8.488 14 3 3 3 382 43 8.76 3 3 1304390.625 2 cell communication;cell death;cell differentiation;cell organization and biogenesis;cellular component movement;cellular homeostasis;defense response;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;endoplasmic reticulum;endosome;Golgi;membrane;mitochondrion;vacuole protein binding;signal transducer activity;transporter activity "Pf00029, Pf03508, Pf10582" 14609 ENSMUSG00000050953.10 Gja1 10 Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Formation of annular gap junctions; c-src mediated regulation of Cx43 function and closure of gap junctions Arrhythmogenic right ventricular cardiomyopathy (ARVC); Gap junction 0 High Q60737 Casein kinase II subunit alpha OS=Mus musculus OX=10090 GN=Csnk2a1 PE=1 SV=2 0 4.807 4 1 3 1 391 45.1 7.74 1 1 1 1 1 1 544208.1875 2698916 3642423.75 3524866.25 1 1 1 1 cell death;metabolic process;regulation of biological process;response to stimulus chromosome;cytoplasm;membrane;nucleus catalytic activity;enzyme regulator activity;nucleotide binding;protein binding "Pf00069, Pf01633, Pf01636, Pf07714" 12995 ENSMUSG00000101523.1; ENSMUSG00000074698.10 Csnk2a1 2; 1 WNT mediated activation of DVL; Regulation of TP53 Activity through Phosphorylation; Synthesis of PC; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Condensation of Prometaphase Chromosomes; Receptor Mediated Mitophagy; Regulation of PTEN stability and activity; Signal transduction by L1; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Herpes simplex infection; Wnt signaling pathway; Epstein-Barr virus infection; Adherens junction; Ribosome biogenesis in eukaryotes; NF-kappa B signaling pathway; Tight junction; Measles 0 High P17427 AP-2 complex subunit alpha-2 OS=Mus musculus OX=10090 GN=Ap2a2 PE=1 SV=2 0 3.944 2 1 3 1 938 104 6.93 1 1 1 1 1 1 237293.8125 272807.625 571428.5 1 1 1 regulation of biological process;transport Golgi;membrane protein binding;transporter activity "Pf01602, Pf02296, Pf02883, Pf13646" 11772 ENSMUSG00000002957.11 Ap2a2 7 "WNT5A-dependent internalization of FZD4; Trafficking of GluR2-containing AMPA receptors; Neutrophil degranulation; VLDLR internalisation and degradation; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Recycling pathway of L1; MHC class II antigen presentation; Cargo recognition for clathrin-mediated endocytosis; LDL clearance" Endocytosis; Endocrine and other factor-regulated calcium reabsorption; Huntington's disease; Synaptic vesicle cycle 0 High A0A0G2JFX7 RNA-binding protein 8A OS=Mus musculus OX=10090 GN=Rbm8a PE=1 SV=1 0 8.294 23 3 3 1 171 19.1 4.97 3 3 metabolic process;transport cytoplasm;nucleus RNA binding "Pf00076, Pf08777, Pf13893, Pf14259" ENSMUSG00000038374.10 3 0 High P19536 "Cytochrome c oxidase subunit 5B, mitochondrial OS=Mus musculus OX=10090 GN=Cox5b PE=1 SV=1" 0 6.354 27 3 3 3 128 13.8 8.38 1 2 1 2 1829502.75 13774390 5415872.625 41101340 1 3 2 3 metabolic process;transport membrane;mitochondrion catalytic activity;metal ion binding;transporter activity Pf01215 12859 Cox5b 1 0 High O35343 Importin subunit alpha-3 OS=Mus musculus OX=10090 GN=Kpna4 PE=1 SV=1 0 5.069 3 1 3 1 521 57.9 4.94 1 1 1 2 176084.2109 302649.8125 1 1 response to stimulus;transport cytoplasm;cytosol;nucleus protein binding;transporter activity "Pf00514, Pf01602, Pf01749, Pf13513, Pf13646" 16649 ENSMUSG00000027782.10 Kpna4 3 0 High Q99LC3 "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Mus musculus OX=10090 GN=Ndufa10 PE=1 SV=1" 0 8.068 8 3 3 3 355 40.6 7.78 3 3 826327.8125 7619327.5 1 2 cell organization and biogenesis;metabolic process;transport mitochondrion;organelle lumen catalytic activity "Pf01712, Pf02223" 67273 ENSMUSG00000026260.12 Ndufa10 1 Complex I biogenesis Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High A0A0N4SUH6 RNA-binding protein 8A OS=Mus musculus OX=10090 GN=Rbm8a2 PE=3 SV=1 0 5.452 22 3 3 1 174 19.9 6.43 3 3 2573202 14674202.5 1980485.875 1 3 1 metabolic process;regulation of biological process;transport cytoplasm;nucleus;spliceosomal complex RNA binding "Pf00076, Pf08777, Pf13893, Pf14259" 545388 ENSMUSG00000078184.1 B020018G12Rik; Rbm8a2 1 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript 2 High O55222 Integrin-linked protein kinase OS=Mus musculus OX=10090 GN=Ilk PE=1 SV=2 0.001 3.382 3 2 3 2 452 51.3 8.07 2 1 2 1 989355.9063 1772804.875 2 1 cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane catalytic activity;nucleotide binding;protein binding;signal transducer activity "Pf00023, Pf00069, Pf07714, Pf12796, Pf13606, Pf13637, Pf13857" 16202 ENSMUSG00000030890.16 Ilk 7 Localization of the PINCH-ILK-PARVIN complex to focal adhesions PPAR signaling pathway; Focal adhesion; Endometrial cancer; Axon guidance; Bacterial invasion of epithelial cells 0 High Q9WTP7 "GTP:AMP phosphotransferase AK3, mitochondrial OS=Mus musculus OX=10090 GN=Ak3 PE=1 SV=3" 0 3.714 9 2 3 2 227 25.4 8.84 2 3 2390898.25 2 cell organization and biogenesis;metabolic process mitochondrion;organelle lumen catalytic activity;nucleotide binding;protein binding "Pf00406, Pf05191, Pf13207, Pf13238, Pf13671" 56248 ENSMUSG00000024782.7 Ak3 19 Factors involved in megakaryocyte development and platelet production Purine metabolism 0 High Q9CQL1 Protein mago nashi homolog 2 OS=Mus musculus OX=10090 GN=Magohb PE=2 SV=1 0 8.643 22 3 3 3 146 17.1 6.39 3 3 261295.3281 4831895.5 12880858.75 1 1 2 metabolic process;transport nucleus;spliceosomal complex RNA binding Pf02792 66441 Magohb 6 mRNA surveillance pathway; Spliceosome; RNA transport 0 High A0A0A6YWI9 Immunoglobulin heavy variable V1-11 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-11 PE=4 SV=1 0 5.992 24 2 3 2 117 12.9 8.28 2 3 2202278.375 2 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000102888.1 12 0 High A0A1L1SUN1 60S ribosomal protein L29 (Fragment) OS=Mus musculus OX=10090 GN=Rpl29 PE=1 SV=1 0 8.877 20 2 3 2 94 10.5 11.72 1 1 1 1 1 1 2638827 16599940.25 13223619.5 6388890.25 2 2 2 2 metabolic process ribosome structural molecule activity ENSMUSG00000048758.14 9 0 High Q99L13 "3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Hibadh PE=1 SV=1" 0 8.496 8 2 3 2 335 35.4 8.13 2 1 2 1 4051489.625 2043455.75 4237035.5 2 1 1 metabolic process;transport mitochondrion catalytic activity;nucleotide binding "Pf02254, Pf02826, Pf03446, Pf03807, Pf14833" 58875 ENSMUSG00000029776.11 Hibadh 6 Branched-chain amino acid catabolism "Valine, leucine and isoleucine degradation; Metabolic pathways" 0 High K3W4L3 Prosaposin OS=Mus musculus OX=10090 GN=Psap PE=1 SV=1 0 8.413 4 2 3 2 556 61.3 5.24 1 2 1 2 274686.1563 362927.5938 8674433.5 1 1 2 metabolic process vacuole "Pf02199, Pf03489, Pf05184" ENSMUSG00000004207.14 10 0 High A0A0R4J1J1 Probable hydrolase PNKD OS=Mus musculus OX=10090 GN=Pnkd PE=1 SV=1 0 5.059 20 2 3 2 142 15.6 10.27 1 2 1 2 9544942 1 metabolic process;regulation of biological process cytoplasm;membrane;mitochondrion;nucleus catalytic activity;metal ion binding;protein binding 56695 ENSMUSG00000026179.14 Pnkd 1 0 High P09055 Integrin beta-1 OS=Mus musculus OX=10090 GN=Itgb1 PE=1 SV=1 0 5.927 3 2 3 2 798 88.2 5.94 2 3 cell differentiation;cell growth;cell organization and biogenesis;cellular component movement;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;endosome;membrane metal ion binding;protein binding;receptor activity "Pf00362, Pf07965, Pf08725" 16412 ENSMUSG00000025809.15 Itgb1 8 ECM proteoglycans; Molecules associated with elastic fibres; Laminin interactions; Integrin cell surface interactions; Localization of the PINCH-ILK-PARVIN complex to focal adhesions; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; MET interacts with TNS proteins; MET activates PTK2 signaling; Signal transduction by L1; Syndecan interactions; Fibronectin matrix formation; Basigin interactions Leukocyte transendothelial migration; Hypertrophic cardiomyopathy (HCM); Regulation of actin cytoskeleton; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Focal adhesion; Toxoplasmosis; Platelet activation; Small cell lung cancer; Dilated cardiomyopathy; Axon guidance; Cell adhesion molecules (CAMs); Phagosome; Pertussis; Proteoglycans in cancer; Rap1 signaling pathway; Pathways in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway; Leishmaniasis; Bacterial invasion of epithelial cells 0 Medium Q3UFY0 Ribosomal RNA processing protein 36 homolog OS=Mus musculus OX=10090 GN=Rrp36 PE=1 SV=1 0.016 1.418 3 1 3 1 244 28.6 10.56 1 1 1 1 1 1 29604892 38888704 10627990.5 7473897.5 1 1 1 1 metabolic process nucleus RNA binding Pf06102 224823 Rrp36 17 0 High P62897 "Cytochrome c, somatic OS=Mus musculus OX=10090 GN=Cycs PE=1 SV=2" 0 3.949 10 1 3 1 105 11.6 9.58 1 1 2 1 1148254.375 2076249.625 1 1 cell death;metabolic process;regulation of biological process;transport cytosol;mitochondrion;nucleus metal ion binding;protein binding "Pf00034, Pf13442, Pf14495" 13063; 672195 ENSMUSG00000058927.5; ENSMUSG00000063694.5 Cycs; Gm10053 6; 19 Activation of caspases through apoptosome-mediated cleavage; Formation of apoptosome; Transcriptional activation of mitochondrial biogenesis; Cytochrome c-mediated apoptotic response; Detoxification of Reactive Oxygen Species; Release of apoptotic factors from the mitochondria; Respiratory electron transport; Apoptotic factor-mediated response Herpes simplex infection; Platinum drug resistance; p53 signaling pathway; Amyotrophic lateral sclerosis (ALS); Toxoplasmosis; Metabolic pathways; Small cell lung cancer; Tuberculosis; Hepatitis B; Huntington's disease; Sulfur metabolism; Apoptosis - multiple species; Non-alcoholic fatty liver disease (NAFLD); Parkinson's disease; Legionellosis; Pathways in cancer; Influenza A; Alzheimer's disease; Viral myocarditis; Colorectal cancer; Apoptosis 0 High Q8CEE7 Retinol dehydrogenase 13 OS=Mus musculus OX=10090 GN=Rdh13 PE=1 SV=1 0 6.703 11 3 3 3 334 36.4 8.85 3 3 3429280 1 metabolic process;response to stimulus mitochondrion catalytic activity "Pf00106, Pf03435, Pf08659" 108841 ENSMUSG00000008435.15 Rdh13 7 RA biosynthesis pathway 0 High Q9JHU4 Cytoplasmic dynein 1 heavy chain 1 OS=Mus musculus OX=10090 GN=Dync1h1 PE=1 SV=2 0 6.737 1 3 3 3 4644 531.7 6.42 2 1 2 1 1248305.875 1071585.875 1209899.625 2725222 2 1 1 1 cell division;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;membrane catalytic activity;motor activity;nucleotide binding;protein binding;RNA binding "Pf00769, Pf03028, Pf03915, Pf04156, Pf07246, Pf07728, Pf08385, Pf08393, Pf12774, Pf12775, Pf12777, Pf12780, Pf12781, Pf13173, Pf13207, Pf13401" 13424 ENSMUSG00000018707.13 Dync1h1 12 Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; COPI-mediated anterograde transport; Regulation of PLK1 Activity at G2/M Transition; Neutrophil degranulation; Recruitment of NuMA to mitotic centrosomes; HSP90 chaperone cycle for steroid hormone receptors (SHR); Resolution of Sister Chromatid Cohesion; Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal; COPI-independent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; RHO GTPases Activate Formins; MHC class II antigen presentation Phagosome; Salmonella infection; Vasopressin-regulated water reabsorption 0 High A0A1W2P7B7 T-complex protein 1 subunit beta (Fragment) OS=Mus musculus OX=10090 GN=Cct2 PE=1 SV=1 0.003 3.24 10 2 3 2 217 22.9 6.06 2 1 2 1 1436730.813 801294.5625 2 1 Met-loss+Acetyl [N-Term] metabolic process nucleotide binding;protein binding Pf00118 ENSMUSG00000034024.8 10 0 Medium G3UZX4 Casein kinase II subunit beta OS=Mus musculus OX=10090 GN=Csnk2b PE=1 SV=1 0.034 1.1 3 1 3 1 257 29.2 6.25 1 1 1 1 1 1 4258062 15248227.5 17510485.5 10191979.25 1 1 1 1 metabolic process;regulation of biological process;response to stimulus chromosome;cytoplasm;membrane;nucleus catalytic activity;enzyme regulator activity;metal ion binding;protein binding Pf01214 13001 ENSMUSG00000024387.13 Csnk2b 17 0 High Q8CFX1 GDH/6PGL endoplasmic bifunctional protein OS=Mus musculus OX=10090 GN=H6pd PE=1 SV=2 0 8.446 5 3 3 3 789 88.9 6.93 3 3 2968113.5 1 metabolic process cytoplasm;endoplasmic reticulum;mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf00479, Pf01182, Pf02781" 100198 ENSMUSG00000028980.14 H6pd 4 Metabolic pathways; Pentose phosphate pathway; Carbon metabolism 0 High Q9JII5 DAZ-associated protein 1 OS=Mus musculus OX=10090 GN=Dazap1 PE=1 SV=2 0 6.237 13 3 3 3 406 43.2 8.56 3 3 3564466.188 1170910.875 3 1 cell differentiation;cell proliferation;development;regulation of biological process cytoplasm;cytosol;nucleus RNA binding "Pf00076, Pf13893, Pf14259" 70248 ENSMUSG00000069565.12 Dazap1 10 mRNA surveillance pathway 0 High Q60675 Laminin subunit alpha-2 OS=Mus musculus OX=10090 GN=Lama2 PE=1 SV=2 0 6.659 2 3 3 3 3118 343.6 6.09 3 3 1387612.344 3 cell differentiation;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;extracellular;Golgi;membrane catalytic activity;motor activity;protein binding;structural molecule activity;transporter activity "Pf00038, Pf00052, Pf00053, Pf00054, Pf00055, Pf00261, Pf00435, Pf00769, Pf00804, Pf01442, Pf01496, Pf01576, Pf02210, Pf02463, Pf02996, Pf03302, Pf03343, Pf03938, Pf03999, Pf04582, Pf04615, Pf04778, Pf05130, Pf05384, Pf05483, Pf05557, Pf05622, Pf05667, Pf05701, Pf06008, Pf06009, Pf06160, Pf06810, Pf07926, Pf08317, Pf08429, Pf09486, Pf09728, Pf09730, Pf09731, Pf09755, Pf10174, Pf10473, Pf12128, Pf12325, Pf12718, Pf13166, Pf13385, Pf13514, Pf13851, Pf13949, Pf14643, Pf14662, Pf14817, Pf15397, Pf15450, Pf15619" 16773 ENSMUSG00000019899.16 Lama2 10 MET activates PTK2 signaling; Laminin interactions Hypertrophic cardiomyopathy (HCM); Arrhythmogenic right ventricular cardiomyopathy (ARVC); Focal adhesion; Toxoplasmosis; Small cell lung cancer; Dilated cardiomyopathy; Pathways in cancer; Viral myocarditis; ECM-receptor interaction; PI3K-Akt signaling pathway; Amoebiasis 0 High Q9JJI8 60S ribosomal protein L38 OS=Mus musculus OX=10090 GN=Rpl38 PE=1 SV=3 0 11.581 36 2 3 2 70 8.2 10.1 1 1 1 2 1016137.688 4873429.5 10614198 1 2 2 cell organization and biogenesis;metabolic process;regulation of biological process ribosome RNA binding;structural molecule activity Pf01781 67671; 625646; 664868 ENSMUSG00000057322.12 Rpl38; Rpl38-ps1; Rpl38-ps2 11; 4; 6 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High P08207 Protein S100-A10 OS=Mus musculus OX=10090 GN=S100a10 PE=1 SV=2 0 10.278 29 2 3 2 97 11.2 6.77 2 3 14651571 1 Met-loss [N-Term] cell organization and biogenesis;regulation of biological process;response to stimulus endoplasmic reticulum;extracellular;membrane metal ion binding;protein binding Pf01023 20194 ENSMUSG00000041959.14 S100a10 3 Dissolution of Fibrin Clot 0 High P09103 Protein disulfide-isomerase OS=Mus musculus OX=10090 GN=P4hb PE=1 SV=2 0 14.455 7 3 3 3 509 57 4.88 3 3 22284791 2 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;membrane;organelle lumen catalytic activity;metal ion binding;protein binding;RNA binding "Pf00085, Pf01216, Pf13098, Pf13848, Pf13899, Pf13905" 18453 ENSMUSG00000025130.11 P4hb 11 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Detoxification of Reactive Oxygen Species; Chylomicron assembly; Interleukin-12 family signaling; VLDL assembly; Hedgehog ligand biogenesis; Collagen biosynthesis and modifying enzymes Protein processing in endoplasmic reticulum 0 High Q8K426 Resistin-like gamma OS=Mus musculus OX=10090 GN=Retnlg PE=1 SV=1 0 7.951 38 3 3 3 117 12.5 7.39 2 1 2 1 3433785.75 1381942 1 1 cellular component movement;regulation of biological process;response to stimulus extracellular protein binding Pf06954 245195 ENSMUSG00000022651.5 Retnlg 16 0 High P48758 Carbonyl reductase [NADPH] 1 OS=Mus musculus OX=10090 GN=Cbr1 PE=1 SV=3 0 9.416 13 3 3 3 277 30.6 8.31 1 2 1 2 1799641.469 1698101.5 12388063.75 3 1 3 Met-loss+Acetyl [N-Term] metabolic process cytoplasm;membrane;nucleus catalytic activity "Pf00106, Pf01370, Pf08659, Pf13561" 12408 ENSMUSG00000051483.8 Cbr1 16 Synthesis of Prostaglandins (PG) and Thromboxanes (TX) Metabolic pathways; Arachidonic acid metabolism; Chemical carcinogenesis; Metabolism of xenobiotics by cytochrome P450 0 High Q8JZQ2 AFG3-like protein 2 OS=Mus musculus OX=10090 GN=Afg3l2 PE=1 SV=1 0 8.297 3 3 3 3 802 89.5 8.6 3 3 3682225.875 1442409 4115066 15773747.5 2 1 2 2 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00004, Pf01434, Pf05496, Pf06068, Pf06480, Pf07724, Pf07728, Pf13191, Pf13401" 69597 ENSMUSG00000024527.9 Afg3l2 18 Processing of SMDT1 0 High A0A075B5Q5 Immunoglobulin heavy variable 2-9 (Fragment) OS=Mus musculus OX=10090 GN=Ighv2-9 PE=4 SV=1 0 9.927 14 1 3 1 116 12.5 8.16 1 1 2 1 2587703 1626849.75 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000096638.2 LOC674142 12 0 High Q9D5T0 Outer mitochondrial transmembrane helix translocase OS=Mus musculus OX=10090 GN=Atad1 PE=1 SV=1 0 11.41 12 2 3 2 361 40.7 6.9 2 3 75030.69531 1427377.25 1 1 metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion;nucleus catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00004, Pf00910, Pf01078, Pf05496, Pf06068, Pf07724, Pf07726, Pf13173, Pf13191, Pf13207, Pf13479" 67979 ENSMUSG00000013662.5 Atad1 19 0 Medium Q9CQX0 Ubiquitin thioesterase OTUB2 OS=Mus musculus OX=10090 GN=Otub2 PE=1 SV=1 0.042 1.045 3 1 3 1 234 27.3 6.28 1 1 1 1 1 1 14148972 26853720 23503146 34401380 1 1 1 1 metabolic process nucleus catalytic activity;protein binding Pf10275 68149 ENSMUSG00000021203.15 Otub2 12 0 High A0A075B5T5 Immunoglobulin heavy variable V1-5 OS=Mus musculus OX=10090 GN=Ighv1-5 PE=4 SV=1 0 10.923 19 1 3 1 98 10.8 9.07 1 1 2 1 4020431.813 1466227.5 7776355 1 1 1 ENSMUSG00000096499.2 LOC671380 12 0 High P47962 60S ribosomal protein L5 OS=Mus musculus OX=10090 GN=Rpl5 PE=1 SV=3 0 7.955 9 2 3 2 297 34.4 9.77 1 2 1 2 746189.0625 4980912.5 2861926.25 5535381.5 1 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity "Pf00861, Pf14204" 100503670 ENSMUSG00000058558.12 Rpl5 5 L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane Ribosome 0 High Q9CQ39 Mediator of RNA polymerase II transcription subunit 21 OS=Mus musculus OX=10090 GN=Med21 PE=1 SV=1 0 6.352 14 1 3 1 144 15.6 4.53 1 1 1 2 55027.94531 444914.2188 220897.5313 429990.0313 1 1 1 1 metabolic process;regulation of biological process nucleus catalytic activity;protein binding Pf11221 108098 ENSMUSG00000030291.12 Med21 6 Mus musculus biological processes; Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes 0 High Q7TNG8 "Probable D-lactate dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Ldhd PE=1 SV=1" 0 12.197 9 2 3 2 484 51.8 6.62 1 2 1 2 1161819.375 2354664.906 1743755.625 5334156.375 1 2 1 2 metabolic process membrane;mitochondrion catalytic activity;nucleotide binding;protein binding "Pf01565, Pf02913" 52815 ENSMUSG00000031958.16 Ldhd 8 Pyruvate metabolism 0 High Q91ZP3 Phosphatidate phosphatase LPIN1 OS=Mus musculus OX=10090 GN=Lpin1 PE=1 SV=1 0 16.486 7 3 3 3 924 101.9 6.74 3 3 585077.4375 8664741.75 1 2 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;endoplasmic reticulum;membrane;mitochondrion;nucleus catalytic activity;protein binding "Pf04571, Pf08235, Pf15017" 14245 Lpin1 12 mTOR signaling pathway; Metabolic pathways; Glycerophospholipid metabolism; Glycerolipid metabolism 0 High Q7TMG7 Atrial natriuretic peptide receptor 3 OS=Mus musculus OX=10090 GN=Npr3 PE=1 SV=1 0 7.502 6 3 3 3 535 59.7 7.09 3 3 8434574.75 2 cell proliferation;regulation of biological process;response to stimulus;transport membrane protein binding;receptor activity;signal transducer activity Pf01094 18162 Npr3 15 0 High O70472 Transmembrane protein 131 OS=Mus musculus OX=10090 GN=Tmem131 PE=2 SV=2 0 13.969 3 3 3 3 1877 204.5 8.54 3 3 membrane Pf12371 56030 ENSMUSG00000026116.11 Tmem131 1 0 High Q9D819 Inorganic pyrophosphatase OS=Mus musculus OX=10090 GN=Ppa1 PE=1 SV=1 0 14.368 16 3 3 3 289 32.6 5.6 1 2 1 2 612699.875 1699138.5 2538622 5475772.5 1 1 1 1 metabolic process cytoplasm catalytic activity;metal ion binding Pf00719 67895 ENSMUSG00000020089.8 Ppa1 10 Cytosolic tRNA aminoacylation; Pyrophosphate hydrolysis Oxidative phosphorylation 0 High Q76MZ3 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Mus musculus OX=10090 GN=Ppp2r1a PE=1 SV=3 0 6.024 9 3 3 3 589 65.3 5.11 1 1 1 1 1 1 506727.6563 287941.8125 575725.0625 865399.75 2 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process chromosome;cytoplasm;cytosol;membrane catalytic activity;enzyme regulator activity;protein binding "Pf02985, Pf13513, Pf13646" 51792 ENSMUSG00000007564.14 Ppp2r1a 17 "Loss of Nlp from mitotic centrosomes; RAF activation; Resolution of Sister Chromatid Cohesion; Separation of Sister Chromatids; Spry regulation of FGF signaling; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Activated TLR4 signalling; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Signaling by GPCR; Regulation of TP53 Degradation; Negative regulation of MAPK pathway; RHO GTPases Activate Formins; Recruitment of NuMA to mitotic centrosomes; Cyclin A/B1/B2 associated events during G2/M transition; Interleukin-20 family signaling; Beta-catenin phosphorylation cascade; Recruitment of mitotic centrosome proteins and complexes; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Regulation of PLK1 Activity at G2/M Transition; CTLA4 inhibitory signaling; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal; ERKs are inactivated; DARPP-32 events; Initiation of Nuclear Envelope Reformation" mRNA surveillance pathway; Chagas disease (American trypanosomiasis); Dopaminergic synapse; Hippo signaling pathway; Oocyte meiosis; Sphingolipid signaling pathway; Long-term depression; TGF-beta signaling pathway; Hepatitis C; PI3K-Akt signaling pathway; AMPK signaling pathway; Tight junction; Adrenergic signaling in cardiomyocytes 0 High Q91VW0 Adenine nucleotide translocase lysine N-methyltransferase OS=Mus musculus OX=10090 GN=Antkmt PE=2 SV=1 0 10.974 28 3 3 3 151 16.2 8.12 3 3 12639262 2 membrane 214917 Fam173a 17 0 High A0A0R4J0I6 Acyl-CoA dehydrogenase family member 11 OS=Mus musculus OX=10090 GN=Acad11 PE=1 SV=1 0 8.282 4 3 3 3 779 87.3 8.43 2 1 2 1 3177261.875 700480.6875 1432151.625 9556738.625 3 1 1 3 metabolic process membrane;mitochondrion;nucleus catalytic activity;nucleotide binding "Pf00441, Pf01636, Pf02770, Pf02771, Pf08028" 102632 ENSMUSG00000090150.10 Acad11 9 Mitochondrial Fatty Acid Beta-Oxidation 0 High O88587 Catechol O-methyltransferase OS=Mus musculus OX=10090 GN=Comt PE=1 SV=2 0 14.08 19 3 3 3 265 29.5 5.83 3 3 304808.2813 833120.8125 14631025 1 1 2 cell communication;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion catalytic activity;metal ion binding "Pf01596, Pf12847, Pf13578, Pf13659" 12846 ENSMUSG00000000326.12; ENSMUSG00000098892.8 Comt 16; CHR_MG3833_MG4220_PATCH Enzymatic degradation of Dopamine by monoamine oxidase; Enzymatic degradation of dopamine by COMT; Methylation Steroid hormone biosynthesis; Dopaminergic synapse; Metabolic pathways; Tyrosine metabolism 0 High Q52KG9 "Chaperonin containing Tcp1, subunit 6a (Zeta) OS=Mus musculus OX=10090 GN=Cct6a PE=2 SV=1" 0 9.161 5 2 3 2 531 58 6.9 1 1 1 1 1 1 532541.2344 122125.8594 645210.25 2 1 1 metabolic process;regulation of biological process;transport cytoplasm;cytosol;membrane nucleotide binding;protein binding;RNA binding "Pf00118, Pf05504" 12466 Cct6a 5 0 High B7ZN28 Papilin OS=Mus musculus OX=10090 GN=Papln PE=1 SV=1 0 3.721 2 2 2 2 1302 141.3 7.81 2 2 2035042.375 5670869 2 1 metabolic process;regulation of biological process extracellular catalytic activity;enzyme regulator activity;metal ion binding;protein binding "Pf00014, Pf00047, Pf00090, Pf05986, Pf07679, Pf07686, Pf08686, Pf13895, Pf13927" 170721 ENSMUSG00000021223.13 Papln 12 0 High E9Q705 BolA-like protein 3 OS=Mus musculus OX=10090 GN=Bola3 PE=1 SV=1 0.006 2.129 7 1 2 1 95 10.8 8.31 1 2 834480.5625 3304421 1 1 Pf01722 ENSMUSG00000045160.14 6 0 High D6RGU1 Nucleolysin TIAR OS=Mus musculus OX=10090 GN=Tial1 PE=1 SV=1 0.006 2.229 6 1 2 1 135 15 6.07 1 2 1153691.5 991637.8125 1 1 cell division;regulation of biological process cytoplasm;nucleus RNA binding "Pf00076, Pf13893, Pf14259" ENSMUSG00000030846.15 7 0 High B0V2N5 Annexin (Fragment) OS=Mus musculus OX=10090 GN=Anxa2 PE=1 SV=1 0 7.083 15 2 2 2 272 31.2 8.29 1 1 1 1 1371279.25 1251706 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cell surface;cytoplasm;cytosol;endosome;extracellular;membrane;nucleus enzyme regulator activity;metal ion binding;protein binding;RNA binding Pf00191 12306 ENSMUSG00000032231.14 Anxa2 9 0 High D3YZJ1 Sequestosome-1 OS=Mus musculus OX=10090 GN=Sqstm1 PE=1 SV=1 0.003 3.061 12 2 2 2 382 41.7 7.72 2 2 2091436.75 2 metal ion binding;protein binding "Pf00564, Pf00569" ENSMUSG00000015837.15 11 0 High Q3U7R1 Extended synaptotagmin-1 OS=Mus musculus OX=10090 GN=Esyt1 PE=1 SV=2 0.004 2.432 2 2 2 2 1092 121.5 5.95 2 2 807142.2031 2 transport endoplasmic reticulum;membrane metal ion binding;protein binding Pf00168 23943 ENSMUSG00000025366.8 Esyt1 10 Glycosphingolipid metabolism 0 High Q61838 Pregnancy zone protein OS=Mus musculus OX=10090 GN=Pzp PE=1 SV=3 0 4.644 2 2 2 2 1495 165.7 6.68 2 2 1564661.5 1594055.25 1 1 regulation of biological process extracellular enzyme regulator activity;protein binding "Pf00207, Pf01835, Pf07677, Pf07678, Pf07703, Pf10569, Pf11974, Pf13249" 11287 ENSMUSG00000030359.14 Pzp 6 0 High A0A0R4J002 Nuclear receptor-binding protein 2 OS=Mus musculus OX=10090 GN=Nrbp2 PE=1 SV=1 0.004 2.532 4 1 2 1 258 29.6 6.27 1 2 7833046.5 1 cell differentiation;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol catalytic activity;nucleotide binding Pf00069 223649 ENSMUSG00000075590.2 Nrbp2 15 0 High Q8BGX2 Mitochondrial import inner membrane translocase subunit Tim29 OS=Mus musculus OX=10090 GN=Timm29 PE=1 SV=1 0 5.397 6 2 2 2 266 29.4 6.73 2 2 7071727.5 1 cell organization and biogenesis;transport membrane;mitochondrion Pf10171 69773 ENSMUSG00000048429.10 1810026J23Rik; Timm29 9 0 High E9Q4F4 Small nuclear ribonucleoprotein E OS=Mus musculus OX=10090 GN=Snrpe PE=1 SV=1 0 7.307 40 2 2 2 91 10.9 8.48 2 2 1338687.125 5491068.25 12243190 4471358.125 1 2 2 2 metabolic process spliceosomal complex Pf01423 ENSMUSG00000090553.8 1 0 High J3QK17 "Glucose transporter type 4, insulin-responsive OS=Mus musculus OX=10090 GN=Slc2a4 PE=1 SV=1" 0.006 2.15 3 2 2 2 480 50.8 9.33 2 2 1997136.055 4095713.75 5165987 16561012.5 2 1 1 2 transport membrane transporter activity Pf00083 ENSMUSG00000018566.14 11 0 High Q61249 Immunoglobulin-binding protein 1 OS=Mus musculus OX=10090 GN=Igbp1 PE=1 SV=1 0 8.366 8 2 2 2 340 38.9 6.18 1 1 1 1 regulation of biological process;response to stimulus cytoplasm;cytosol enzyme regulator activity;protein binding Pf04177 18518 ENSMUSG00000031221.7 Igbp1 X 0 High A2AFI3 "RNA-binding motif protein, X chromosome OS=Mus musculus OX=10090 GN=Rbmx PE=1 SV=1" 0 4.384 4 1 2 1 301 32.7 9.88 1 1 1 1 1245657.25 2095093.375 5679568.5 2205972.75 1 1 1 1 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus membrane;nucleus;spliceosomal complex DNA binding;protein binding;RNA binding "Pf00076, Pf08081, Pf13893, Pf14259" 19655 ENSMUSG00000031134.16 Rbmx X 0 High Q6P8N8 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Mus musculus OX=10090 GN=Clpx PE=1 SV=1" 0 9.346 4 2 2 2 620 67.3 7.55 2 2 3640831.25 1 metabolic process;regulation of biological process cytosol;membrane;mitochondrion;organelle lumen catalytic activity;enzyme regulator activity;metal ion binding;nucleotide binding;protein binding "Pf00004, Pf00158, Pf01078, Pf05729, Pf07724, Pf07726, Pf07728, Pf10431, Pf13191, Pf13401, Pf14532" 270166 ENSMUSG00000015357.10 Clpx 9 0 High Q8CCM6 Mitochondrial import inner membrane translocase subunit Tim21 OS=Mus musculus OX=10090 GN=Timm21 PE=1 SV=2 0 6.319 12 2 2 2 244 27.9 9.95 2 2 4015272 1 0 High Q9D1Q6 Endoplasmic reticulum resident protein 44 OS=Mus musculus OX=10090 GN=Erp44 PE=1 SV=1 0 5.462 5 2 2 2 406 46.8 5.27 2 2 4729246 1 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cell surface;endoplasmic reticulum;membrane;organelle lumen catalytic activity;metal ion binding;protein binding "Pf00085, Pf01216, Pf07449, Pf13098, Pf13848" 76299 ENSMUSG00000028343.10 Erp44 4 Neutrophil degranulation 0 High Q3UNH6 Cyclic AMP-responsive element-binding protein 3 OS=Mus musculus OX=10090 GN=Creb3 PE=2 SV=1 0 7.277 7 2 2 2 379 42.4 4.98 2 2 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;endoplasmic reticulum;Golgi;membrane;nucleus DNA binding;protein binding "Pf00170, Pf03131, Pf07716" 12913 ENSMUSG00000028466.15 Creb3 4 CREB3 factors activate genes Cholinergic synapse; Dopaminergic synapse; TNF signaling pathway; Amphetamine addiction; Insulin resistance; Melanogenesis; Hepatitis B; Thyroid hormone synthesis; Longevity regulating pathway; Huntington's disease; Cocaine addiction; cGMP-PKG signaling pathway; Alcoholism; PI3K-Akt signaling pathway; cAMP signaling pathway; AMPK signaling pathway; Aldosterone synthesis and secretion; Vasopressin-regulated water reabsorption; Insulin secretion; Estrogen signaling pathway; Glucagon signaling pathway; Viral carcinogenesis; Adrenergic signaling in cardiomyocytes; Prostate cancer 0 Medium A6H6A9 Rab GTPase-activating protein 1-like OS=Mus musculus OX=10090 GN=Rabgap1l PE=1 SV=1 0.027 1.177 1 1 2 1 815 92.3 5.31 1 1 1 1 785930.125 41805356 1 1 regulation of biological process;transport endosome;Golgi;nucleus enzyme regulator activity;protein binding "Pf00566, Pf00640, Pf12473" 29809 ENSMUSG00000026721.15 Rabgap1l 1 0 High Q9CWY4 Gem-associated protein 7 OS=Mus musculus OX=10090 GN=Gemin7 PE=2 SV=1 0.007 2.042 12 1 2 1 129 14.2 7.52 1 1 1 1 182413.0625 245560.4531 1 1 Acetyl [N-Term] cell organization and biogenesis;metabolic process cytoplasm;cytosol;nucleus protein binding Pf11095 69731 ENSMUSG00000044709.6 Gemin7 7 snRNP Assembly RNA transport 0 High Q8R1I1 Cytochrome b-c1 complex subunit 9 OS=Mus musculus OX=10090 GN=Uqcr10 PE=1 SV=1 0.009 1.823 11 1 2 1 64 7.4 9.19 1 1 1 1 cell organization and biogenesis;metabolic process;transport membrane;mitochondrion catalytic activity;transporter activity Pf05365 66152 ENSMUSG00000059534.8 Uqcr10 11 Respiratory electron transport Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Cardiac muscle contraction 0 High Q9R0P5 Destrin OS=Mus musculus OX=10090 GN=Dstn PE=1 SV=3 0 4.615 12 2 2 1 165 18.5 7.97 1 1 1 1 1096362.5 1753121.625 1 1 Met-loss+Acetyl [N-Term] cell organization and biogenesis;cellular component movement;regulation of biological process cytoplasm;cytoskeleton protein binding Pf00241 56431 ENSMUSG00000015932.8 Dstn 2 0 High Q64516 Glycerol kinase OS=Mus musculus OX=10090 GN=Gk PE=1 SV=2 0 5.428 4 2 2 2 559 61.2 5.87 1 1 1 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;nucleotide binding;protein binding "Pf00370, Pf02782" 14933 ENSMUSG00000025059.16 Gyk; Gk X Triglyceride biosynthesis PPAR signaling pathway; Metabolic pathways; Glycerolipid metabolism 0 High E9Q1S3 Protein transport protein SEC23 OS=Mus musculus OX=10090 GN=Sec23a PE=1 SV=1 0 6.207 4 2 2 2 736 82.9 7.46 1 1 1 1 2069377.5 3948199.75 2681039 2 2 1 transport cytoplasm;membrane metal ion binding "Pf00626, Pf04810, Pf04811, Pf04815, Pf08033" ENSMUSG00000020986.13 12 0 High Q9JIX8 Apoptotic chromatin condensation inducer in the nucleus OS=Mus musculus OX=10090 GN=Acin1 PE=1 SV=3 0 7.898 2 2 2 2 1338 150.6 5.91 1 1 1 1 cell death;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process cytosol;membrane;nucleus RNA binding "Pf02037, Pf13893" 56215 ENSMUSG00000022185.18 Acin1 14 Apoptotic cleavage of cellular proteins mRNA surveillance pathway; Spliceosome; RNA transport 0 High Q9D7W5 Mediator of RNA polymerase II transcription subunit 8 OS=Mus musculus OX=10090 GN=Med8 PE=1 SV=1 0 6.02 9 2 2 2 268 29.2 6.95 2 2 2181219.625 1962911.125 1653408.5 2378976.75 2 1 1 1 metabolic process;regulation of biological process nucleus protein binding Pf10232 80509 ENSMUSG00000006392.16 Med8 4 Generic Transcription Pathway; Mus musculus biological processes; Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes Herpes simplex infection 0 High Q9CQQ4 Gem-associated protein 2 OS=Mus musculus OX=10090 GN=Gemin2 PE=2 SV=1 0 4.438 6 1 2 1 269 30.4 5.53 1 2 244327.9375 325843.875 344041.25 1 1 1 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process cytoplasm;cytosol;nucleus;spliceosomal complex Pf04938 66603 ENSMUSG00000060121.15 Gemin2; Sip1 12 snRNP Assembly RNA transport 0 High A0A1W2P7X3 Acid phosphatase OS=Mus musculus OX=10090 GN=Acp1 PE=1 SV=1 0.003 3.049 8 1 2 1 114 12.6 7.81 1 1 1 1 1303733.25 1947018.5 2654113 10730257 1 1 1 1 metabolic process catalytic activity Pf01451 ENSMUSG00000044573.15 12 0 High Q9CQE8 "RNA transcription, translation and transport factor protein OS=Mus musculus OX=10090 GN=RTRAF PE=1 SV=1" 0.004 2.439 4 1 2 1 244 28.1 6.89 1 1 1 1 1081254.25 962634.1875 2793277.75 1 1 1 metabolic process;regulation of biological process cytoplasm;cytoskeleton;cytosol;nucleus protein binding;RNA binding Pf10036 68045 ENSMUSG00000021807.5 2700060E02Rik; Rtraf 14 0 High Q9D6J6 "NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Mus musculus OX=10090 GN=Ndufv2 PE=1 SV=2" 0 4.668 10 2 2 2 248 27.3 7.4 1 1 1 1 1154727.906 830688.4375 1930635.375 2 1 1 metabolic process;transport membrane;mitochondrion catalytic activity;metal ion binding Pf01257 72900 ENSMUSG00000024099.14 Ndufv2 17 Complex I biogenesis Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High A0A0G2JF45 Immunoglobulin kappa variable 14-130 (Fragment) OS=Mus musculus OX=10090 GN=Igkv14-130 PE=4 SV=4 0 4.401 11 1 2 1 117 13.1 4.56 1 2 1222122.375 13486988 2059219.75 1 1 1 response to stimulus "Pf00047, Pf07679, Pf07686, Pf13927" 628072 ENSMUSG00000096461.5 Igkv14-130 6 0 High Q80ZK0 "28S ribosomal protein S10, mitochondrial OS=Mus musculus OX=10090 GN=Mrps10 PE=1 SV=1" 0 6.879 19 2 2 2 160 18.7 8.84 1 1 1 1 155087.75 2770154.25 2123110.5 1 1 1 metabolic process mitochondrion;ribosome structural molecule activity Pf00338 64657 Mrps10 17 0 High P01629 Ig kappa chain V-II region 2S1.3 OS=Mus musculus OX=10090 PE=1 SV=1 0.006 2.18 26 2 2 2 112 12.2 7.94 2 2 25994251.5 2 "Pf07679, Pf07686" 0 Medium A2AQM9 Nuclear receptor coactivator 6 (Fragment) OS=Mus musculus OX=10090 GN=Ncoa6 PE=1 SV=8 0.011 1.631 0 1 2 1 1516 163 9.6 1 2 1825238.375 1 regulation of biological process nucleus "Pf09606, Pf09770, Pf13820" ENSMUSG00000038369.14 2 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 0 High P01887 Beta-2-microglobulin OS=Mus musculus OX=10090 GN=B2m PE=1 SV=2 0 6.158 16 2 2 2 119 13.8 8.44 2 2 442307.9688 7580457.5 1 1 cell differentiation;defense response;metabolic process;regulation of biological process;response to stimulus;transport cytosol;extracellular;Golgi;membrane protein binding Pf07654 12010 ENSMUSG00000060802.8 B2m 2 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Endosomal/Vacuolar pathway; Neutrophil degranulation; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; ER-Phagosome pathway; DAP12 signaling" Antigen processing and presentation 0 High P31786 Acyl-CoA-binding protein OS=Mus musculus OX=10090 GN=Dbi PE=1 SV=2 0 7.021 38 2 2 2 87 10 8.82 1 1 1 1 2854839.5 6492952 3618343.625 5530131 2 2 2 2 Met-loss+Acetyl [N-Term] cell proliferation;defense response;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;Golgi;membrane;mitochondrion;nucleus protein binding Pf00887 13167 ENSMUSG00000026385.16 Dbi 1 Mitochondrial Fatty Acid Beta-Oxidation PPAR signaling pathway 0 High A6H6E2 Multimerin-2 OS=Mus musculus OX=10090 GN=Mmrn2 PE=1 SV=1 0.003 2.861 3 2 2 2 943 105.1 5.57 2 2 1157473.219 2 cellular component movement;regulation of biological process extracellular protein binding "Pf00386, Pf07546" 105450 ENSMUSG00000041445.8 Mmrn2 14 0 High Q9R1Q9 V-type proton ATPase subunit S1 OS=Mus musculus OX=10090 GN=Atp6ap1 PE=1 SV=1 0 9.946 8 2 2 2 463 51 5.92 2 2 5589379 1 cell death;cell organization and biogenesis;cellular homeostasis;regulation of biological process;response to stimulus;transport endoplasmic reticulum;membrane catalytic activity;nucleotide binding;protein binding;transporter activity Pf05827 54411 ENSMUSG00000019087.13 Atp6ap1 X Ion channel transport; Transferrin endocytosis and recycling; Insulin receptor recycling Rheumatoid arthritis; Metabolic pathways; Tuberculosis; Hepatitis B; Lysosome; Phagosome; Oxidative phosphorylation 0 High Q8BXZ1 Protein disulfide-isomerase TMX3 OS=Mus musculus OX=10090 GN=Tmx3 PE=1 SV=2 0 5.339 6 2 2 2 456 51.8 5.16 2 2 5730951.5 1 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cell surface;endoplasmic reticulum;membrane catalytic activity "Pf00085, Pf13098, Pf13848, Pf13899" 67988 ENSMUSG00000024614.6 Tmx3 18 Platelet degranulation 0 High Q91VK2 Eef1d protein OS=Mus musculus OX=10090 GN=Eef1d PE=1 SV=1 0.003 3.296 4 1 2 1 276 30.6 4.98 1 2 1758681.375 1701276.625 1 1 Met-loss+Acetyl [N-Term] metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;endoplasmic reticulum;nucleus DNA binding;protein binding;RNA binding;signal transducer activity Pf00736 66656 ENSMUSG00000055762.15 Eef1d 15 Eukaryotic Translation Elongation 0 High A0A3Q4EC24 Mitochondrial carrier homolog 1 (Fragment) OS=Mus musculus OX=10090 GN=Mtch1 PE=1 SV=1 0 3.709 4 1 2 1 299 33.1 9.22 1 2 6474787.5 1 0 High P24369 Peptidyl-prolyl cis-trans isomerase B OS=Mus musculus OX=10090 GN=Ppib PE=1 SV=2 0 3.969 8 2 2 2 216 23.7 9.55 1 1 1 1 631593.1406 1798760.5 1064185.125 8559187.75 2 1 1 2 metabolic process;regulation of biological process endoplasmic reticulum;membrane;nucleus;organelle lumen catalytic activity;protein binding;RNA binding Pf00160 19035 ENSMUSG00000032383.7 Ppib 9 Collagen biosynthesis and modifying enzymes 0 High V9GX87 Double-stranded RNA-binding protein Staufen homolog 1 OS=Mus musculus OX=10090 GN=Stau1 PE=1 SV=1 0.003 2.708 2 1 2 1 436 48.7 9.86 1 2 1555786.75 1844632.375 1797449.875 6679905.5 1 1 1 1 RNA binding "Pf00035, Pf14709" ENSMUSG00000039536.16 2 0 High P51885 Lumican OS=Mus musculus OX=10090 GN=Lum PE=1 SV=2 0 4.469 5 2 2 2 338 38.2 6.43 2 2 1740747.813 1062665.75 2 1 cell organization and biogenesis;regulation of biological process;response to stimulus extracellular protein binding "Pf01462, Pf12799, Pf13855" 17022 ENSMUSG00000036446.5 Lum 10 Keratan sulfate degradation; Keratan sulfate biosynthesis; Integrin cell surface interactions Proteoglycans in cancer 0 High G3UXA6 Polypyrimidine tract-binding protein 3 OS=Mus musculus OX=10090 GN=Ptbp3 PE=1 SV=1 0 3.933 4 2 2 1 554 59.7 8.94 2 2 65944.21875 136333.0156 1 1 Acetyl [N-Term] cell differentiation;metabolic process;regulation of biological process nucleus RNA binding "Pf00076, Pf13893, Pf14259" 230257 ENSMUSG00000028382.15 Ptbp3; Rod1 4 0 High Q8R2L5 "28S ribosomal protein S18c, mitochondrial OS=Mus musculus OX=10090 GN=Mrps18c PE=1 SV=1" 0 8.365 19 2 2 2 143 16.3 9.41 2 2 1326348.875 1 cell organization and biogenesis;metabolic process mitochondrion;ribosome structural molecule activity Pf01084 68735 ENSMUSG00000016833.14 Mrps18c 5 Mitochondrial translation termination; Mitochondrial translation elongation Ribosome 0 High Q91VN4 MICOS complex subunit Mic25 OS=Mus musculus OX=10090 GN=Chchd6 PE=1 SV=2 0 4.117 5 1 2 1 273 29.8 8.41 1 1 1 1 1356346.75 1674645 5671026.5 1 1 1 cell organization and biogenesis;response to stimulus cytosol;membrane;mitochondrion "Pf05300, Pf06747" 66098 ENSMUSG00000030086.16 Chchd6 6 0 High Q9CRD2 ER membrane protein complex subunit 2 OS=Mus musculus OX=10090 GN=Emc2 PE=1 SV=1 0.007 1.885 4 1 2 1 297 34.9 6.81 1 2 metabolic process cytoplasm;endoplasmic reticulum;mitochondrion;nucleus protein binding "Pf13414, Pf13432, Pf14559" 66736 ENSMUSG00000022337.6 Emc2 15 0 High Q8C7H1 "Methylmalonic aciduria type A homolog, mitochondrial OS=Mus musculus OX=10090 GN=Mmaa PE=1 SV=1" 0 6.772 7 2 2 2 415 45.9 9.32 2 2 metabolic process mitochondrion catalytic activity;nucleotide binding "Pf02492, Pf03205, Pf03308, Pf12846" 109136 ENSMUSG00000037022.3 Mmaa 8 "Propionyl-CoA catabolism; Cobalamin (Cbl, vitamin B12) transport and metabolism" 0 High Q8CGB6 Tensin-2 OS=Mus musculus OX=10090 GN=Tns2 PE=1 SV=1 0 3.855 2 2 2 2 1400 151.9 8.48 2 2 805084.8438 2 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus membrane catalytic activity;metal ion binding;protein binding;receptor activity;signal transducer activity "Pf00017, Pf00130, Pf03154, Pf05109, Pf08416, Pf09770, Pf10409, Pf13388" 209039 ENSMUSG00000037003.15 Tenc1; Tns2 15 0 High Q01768 Nucleoside diphosphate kinase B OS=Mus musculus OX=10090 GN=Nme2 PE=1 SV=1 0.001 3.415 17 2 2 2 152 17.4 7.5 2 2 1390146.688 2 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding Pf00334 18103 ENSMUSG00000020857.11 Nme2 11 Interconversion of nucleotide di- and triphosphates; Neutrophil degranulation Metabolic pathways; Purine metabolism; Pyrimidine metabolism 0 Medium D6RGM2 O-phosphoseryl-tRNA(Sec) selenium transferase OS=Mus musculus OX=10090 GN=Sepsecs PE=1 SV=1 0.01 1.668 8 1 2 1 91 10.2 4.84 1 2 1249133.125 2773168 1 1 metabolic process;regulation of biological process cytoplasm;nucleus catalytic activity;RNA binding ENSMUSG00000029173.12 5 0 High Q8BG51 Mitochondrial Rho GTPase 1 OS=Mus musculus OX=10090 GN=Rhot1 PE=1 SV=1 0 5.196 3 2 2 2 631 72.2 6.49 2 2 552580.2813 8572035.5 2 2 cell organization and biogenesis;cellular component movement;cellular homeostasis;regulation of biological process;response to stimulus;transport membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding "Pf00071, Pf08355, Pf08356, Pf08477" 59040 ENSMUSG00000017686.16 Rhot1 11 Ub-specific processing proteases; Rho GTPase cycle 0 High Q9D5V5 Cullin-5 OS=Mus musculus OX=10090 GN=Cul5 PE=1 SV=3 0.003 3.128 2 2 2 2 780 90.9 7.81 2 2 455488.25 1 cellular component movement;cellular homeostasis;metabolic process;response to stimulus cytoplasm;membrane;nucleus catalytic activity;protein binding "Pf00888, Pf10557" 75717 Cul5 9 Ubiquitin mediated proteolysis 0 High P62892 60S ribosomal protein L39 OS=Mus musculus OX=10090 GN=Rpl39 PE=1 SV=2 0.004 2.43 20 1 2 1 51 6.4 12.56 1 1 1 1 1208286 1477623 2955431 1 1 1 defense response;metabolic process;response to stimulus ribosome protein binding;RNA binding;structural molecule activity Pf00832 67248 ENSMUSG00000079641.3 Rpl39 X Ribosome 0 High P14069 Protein S100-A6 OS=Mus musculus OX=10090 GN=S100a6 PE=1 SV=3 0.001 3.376 47 2 2 2 89 10 5.48 2 2 1011323.813 1486093.125 7397628.5 1 1 2 transport cytoplasm;cytosol;extracellular;membrane;nucleus metal ion binding;protein binding;transporter activity Pf01023 20200 ENSMUSG00000001025.8 S100a6 3 0 High P16110 Galectin-3 OS=Mus musculus OX=10090 GN=Lgals3 PE=1 SV=3 0 5.035 9 2 2 2 264 27.5 8.38 2 2 648532.1563 2 cell differentiation;cell organization and biogenesis;cellular component movement;defense response;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;extracellular;membrane;nucleus;spliceosomal complex protein binding;receptor activity;RNA binding;signal transducer activity Pf00337 16854 Lgals3 14 0 High G3UZG6 Cytochrome-b5 reductase (Fragment) OS=Mus musculus OX=10090 GN=Cyb5r1 PE=1 SV=1 0.003 2.959 6 1 2 1 176 19.4 9.51 1 2 metabolic process membrane;mitochondrion catalytic activity "Pf00175, Pf00970" 72017 ENSMUSG00000026456.18 Cyb5r1 1 0 High A0A338P7H5 Alpha-2-HS-glycoprotein OS=Mus musculus OX=10090 GN=Ahsg PE=1 SV=1 0 3.69 8 1 2 1 301 32.2 6.95 1 1 1 1 116810.7344 170815.875 478228.0625 1 1 1 0 High Q9WUR2 Enoyl-CoA delta isomerase 2 OS=Mus musculus OX=10090 GN=Eci2 PE=1 SV=2 0.003 3.108 4 2 2 2 391 43.2 8.92 1 1 1 1 1395752.563 6444531.25 2 2 metabolic process membrane;mitochondrion;organelle lumen catalytic activity;protein binding "Pf00378, Pf00887" 23986 ENSMUSG00000021417.14 Eci2 13 Beta-oxidation of very long chain fatty acids Fatty acid degradation; Peroxisome 0 Medium A2AGT5 Cytoskeleton-associated protein 5 OS=Mus musculus OX=10090 GN=Ckap5 PE=1 SV=1 0.01 1.68 2 2 2 2 2032 225.5 7.96 1 1 1 1 cell division;cell organization and biogenesis;transport chromosome;cytoplasm;cytoskeleton;membrane protein binding 75786 Ckap5 2 0 High Q69ZQ1 Myogenesis-regulating glycosidase OS=Mus musculus OX=10090 GN=Myorg PE=1 SV=2 0 5.647 3 2 2 2 716 81.3 8.29 2 2 4026823 1 metabolic process;regulation of biological process membrane catalytic activity;protein binding Pf01055 329828 ENSMUSG00000046312.4 AI464131 4 0 High Q62165 Dystroglycan OS=Mus musculus OX=10090 GN=Dag1 PE=1 SV=4 0 5.752 4 2 2 2 893 96.8 8.44 2 2 1571709.438 2 cell differentiation;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;extracellular;membrane;nucleus metal ion binding;protein binding;structural molecule activity Pf05454 13138 ENSMUSG00000039952.15 Dag1 9 Regulation of expression of SLITs and ROBOs; O-linked glycosylation; Integrin cell surface interactions Hypertrophic cardiomyopathy (HCM); Arrhythmogenic right ventricular cardiomyopathy (ARVC); Dilated cardiomyopathy; Viral myocarditis; ECM-receptor interaction 0 High A0A494BAK4 Endoplasmic reticulum-Golgi intermediate compartment protein 1 OS=Mus musculus OX=10090 GN=Ergic1 PE=1 SV=1 0.003 3.306 7 2 2 2 247 27.7 7.61 2 2 8482252 2 0 High P08228 Superoxide dismutase [Cu-Zn] OS=Mus musculus OX=10090 GN=Sod1 PE=1 SV=2 0 5.394 16 2 2 2 154 15.9 6.51 1 1 1 1 998462.4063 4994230.125 1716938.375 2 2 1 cell organization and biogenesis;cellular component movement;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;extracellular;membrane;mitochondrion;nucleus;vacuole antioxidant activity;catalytic activity;metal ion binding;protein binding Pf00080 20655 ENSMUSG00000022982.9 Sod1 16 Platelet degranulation ; Detoxification of Reactive Oxygen Species Amyotrophic lateral sclerosis (ALS); Huntington's disease; Prion diseases; Longevity regulating pathway - multiple species; Peroxisome 0 High Q9DB40 Mediator of RNA polymerase II transcription subunit 27 OS=Mus musculus OX=10090 GN=Med27 PE=2 SV=2 0 5.962 11 2 2 2 311 35.3 9.31 2 2 2085591.469 1916564.875 2 1 metabolic process;regulation of biological process cytosol;nucleus catalytic activity Pf11571 68975 ENSMUSG00000026799.15 Med27 2 Generic Transcription Pathway; Mus musculus biological processes; Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes Thyroid hormone signaling pathway 0 High Q64012 RNA-binding protein Raly OS=Mus musculus OX=10090 GN=Raly PE=1 SV=3 0.001 3.514 6 2 2 2 312 33.2 8.84 1 1 1 1 1340523.25 1438750.25 2480734.25 1719137.625 2 1 1 1 metabolic process;regulation of biological process nucleus;spliceosomal complex RNA binding "Pf00076, Pf13893, Pf14259" 19383 ENSMUSG00000027593.15 Raly 2 0 High A6PW47 Mediator complex subunit 24 OS=Mus musculus OX=10090 GN=Med24 PE=1 SV=1 0 4.609 3 2 2 2 1006 111.8 6.92 1 1 1 1 592325.875 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus nucleus catalytic activity;protein binding;receptor activity Pf11277 23989 ENSMUSG00000017210.14 Med24 11 0 High D3YXU8 Hyaluronidase OS=Mus musculus OX=10090 GN=Hyal1 PE=1 SV=1 0 12.628 11 2 2 2 432 49 6.73 2 2 9387082.5 2 metabolic process catalytic activity Pf01630 ENSMUSG00000010051.15 9 0 High O88456 Calpain small subunit 1 OS=Mus musculus OX=10090 GN=Capns1 PE=1 SV=1 0 3.974 3 1 2 1 269 28.4 5.63 1 1 1 1 246104.7188 444607.0313 941265.25 1 1 1 Acetyl [N-Term] metabolic process cytoplasm;cytosol;membrane catalytic activity;metal ion binding;protein binding Pf13833 12336 Capns1 7 0 High Q9CQR2 40S ribosomal protein S21 OS=Mus musculus OX=10090 GN=Rps21 PE=1 SV=1 0 4.395 28 2 2 2 83 9.1 8.51 1 1 1 1 749821.3125 1694345 2028611 2056775 1 1 1 1 metabolic process ribosome protein binding;RNA binding;structural molecule activity Pf01249 66481 ENSMUSG00000039001.12 Rps21 2 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High O08997 Copper transport protein ATOX1 OS=Mus musculus OX=10090 GN=Atox1 PE=1 SV=1 0.003 2.878 32 2 2 2 68 7.3 6.51 2 2 1152008.75 1 cellular homeostasis;response to stimulus;transport cytoplasm;cytosol metal ion binding;protein binding;transporter activity Pf00403 11927 ENSMUSG00000018585.9 Atox1 11 Ion influx/efflux at host-pathogen interface Mineral absorption 0 High Q9WTL4 Insulin receptor-related protein OS=Mus musculus OX=10090 GN=Insrr PE=1 SV=2 0.001 3.428 1 2 2 1 1300 144.8 6.64 2 2 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus membrane catalytic activity;nucleotide binding;protein binding;receptor activity;signal transducer activity "Pf00041, Pf00069, Pf00757, Pf01030, Pf05287, Pf07714" 23920 ENSMUSG00000005640.11 Insrr 3 Regulation of actin cytoskeleton; Prostate cancer 0 High Q99MQ4 Asporin OS=Mus musculus OX=10090 GN=Aspn PE=1 SV=1 0.006 2.304 3 1 2 1 373 42.5 8.57 1 1 1 1 1432637.875 1476258.125 2372302.75 1 1 1 regulation of biological process;response to stimulus;transport cytoplasm;extracellular enzyme regulator activity;metal ion binding;protein binding;transporter activity "Pf01462, Pf12799, Pf13855" 66695 ENSMUSG00000021388.14 Aspn 13 0 High Q61087 Laminin subunit beta-3 OS=Mus musculus OX=10090 GN=Lamb3 PE=1 SV=2 0 3.829 3 2 2 2 1168 128.8 7.47 1 1 1 1 1564661.5 1594055.25 1 1 cell differentiation extracellular protein binding "Pf00053, Pf00055" 16780 ENSMUSG00000026639.18 Lamb3 1 Anchoring fibril formation; Laminin interactions; Degradation of the extracellular matrix; Type I hemidesmosome assembly; MET activates PTK2 signaling Focal adhesion; Toxoplasmosis; Small cell lung cancer; Pathways in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway; Amoebiasis 0 High P61804 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 OS=Mus musculus OX=10090 GN=Dad1 PE=1 SV=3 0 5.135 19 2 2 2 113 12.5 7.08 2 2 9221914 1 Met-loss+Acetyl [N-Term] cell death;metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;membrane catalytic activity Pf02109 13135 ENSMUSG00000022174.8 Dad1 14 Metabolic pathways; N-Glycan biosynthesis; Protein processing in endoplasmic reticulum 0 High Q9QYI6 DnaJ homolog subfamily B member 9 OS=Mus musculus OX=10090 GN=Dnajb9 PE=1 SV=2 0 8.148 10 2 2 2 222 25.6 8.28 2 2 9788861 1 metabolic process cytoplasm;endoplasmic reticulum;organelle lumen protein binding Pf00226 27362 ENSMUSG00000014905.4 Dnajb9 12 0 High A0A0B4J1I7 Immunoglobulin kappa variable 4-68 (Fragment) OS=Mus musculus OX=10090 GN=Igkv4-68 PE=4 SV=1 0 4.648 17 1 2 1 117 12.7 7.96 1 1 1 1 6888300 5333169.5 2395857.75 1 1 1 response to stimulus "Pf00047, Pf07686" 384515 ENSMUSG00000076549.2 Igkv4-68 6 0 Medium Q9D125 "28S ribosomal protein S25, mitochondrial OS=Mus musculus OX=10090 GN=Mrps25 PE=1 SV=1" 0.025 1.237 5 1 2 1 171 19.9 9.23 1 1 1 1 2754392 3376499.5 5003927 1 1 1 cell organization and biogenesis;metabolic process mitochondrion;ribosome structural molecule activity Pf05047 64658 ENSMUSG00000014551.8 Mrps25 6 Mitochondrial translation termination; Mitochondrial translation elongation 0 High B7FAV1 "Filamin, alpha (Fragment) OS=Mus musculus OX=10090 GN=Flna PE=1 SV=1" 0 7.135 1 2 2 2 2583 274.5 5.97 2 2 1792178.063 2 cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;membrane;nucleus protein binding;RNA binding;signal transducer activity "Pf00307, Pf00630" 192176 ENSMUSG00000031328.15 Flna X 0 High A0A0A6YWN3 Immunoglobulin heavy variable 13-2 (Fragment) OS=Mus musculus OX=10090 GN=Ighv13-2 PE=4 SV=1 0 7.72 23 2 2 2 119 13.4 8.65 2 2 2822355.75 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000076671.5 12 0 High Q62189 U1 small nuclear ribonucleoprotein A OS=Mus musculus OX=10090 GN=Snrpa PE=1 SV=3 0.003 3.244 9 2 2 2 287 31.8 9.8 1 1 1 1 3655732.75 1859509.75 1 1 metabolic process nucleus;spliceosomal complex RNA binding "Pf00076, Pf13893, Pf14259" 53607 ENSMUSG00000061479.15 Snrpa 7 mRNA Splicing - Major Pathway Spliceosome 0 High A0A075B5S5 Immunoglobulin heavy variable 7-4 OS=Mus musculus OX=10090 GN=Ighv7-4 PE=4 SV=1 0 5.95 13 1 2 1 120 13.4 8.9 1 1 1 1 1598584.5 1496733.375 1 1 ENSMUSG00000076668.4 12 0 High P58019 CD59B glycoprotein OS=Mus musculus OX=10090 GN=Cd59b PE=2 SV=2 0 4.255 9 1 2 1 129 14.2 7.91 1 2 12219194 1 regulation of biological process;response to stimulus cell surface;extracellular;membrane protein binding Pf00021 333883 ENSMUSG00000068686.12 Cd59b 2 Regulation of Complement cascade; Cargo concentration in the ER; COPI-mediated anterograde transport; COPII (Coat Protein 2) Mediated Vesicle Transport; Neutrophil degranulation Complement and coagulation cascades; Hematopoietic cell lineage 0 High P23906 Interferon regulatory factor 2 OS=Mus musculus OX=10090 GN=Irf2 PE=1 SV=1 0 4.83 5 2 2 2 349 39.4 7.49 2 2 2774812.75 5412521 1 1 cell proliferation;defense response;metabolic process;regulation of biological process;response to stimulus cytosol;nucleus catalytic activity;DNA binding "Pf00605, Pf01126" 16363 ENSMUSG00000031627.9 Irf2 8 Factors involved in megakaryocyte development and platelet production; TRAF6 mediated IRF7 activation 0 High Q9CZ82 Mediator of RNA polymerase II transcription subunit 18 OS=Mus musculus OX=10090 GN=Med18 PE=1 SV=1 0.001 3.621 7 1 2 1 208 23.6 6.54 1 2 498004.7813 1 metabolic process;regulation of biological process nucleus catalytic activity Pf09637 67219 ENSMUSG00000066042.4 Med18 4 Mus musculus biological processes; Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes 0 High O54950 5'-AMP-activated protein kinase subunit gamma-1 OS=Mus musculus OX=10090 GN=Prkag1 PE=1 SV=2 0 8.681 6 1 2 1 330 37.5 7.14 1 2 73843.38281 1102161.969 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;transport cytosol;membrane;nucleus catalytic activity;nucleotide binding;protein binding Pf00571 19082 ENSMUSG00000067713.6 Prkag1 15 Macroautophagy; Regulation of TP53 Activity through Phosphorylation; Energy dependent regulation of mTOR by LKB1-AMPK; TP53 Regulates Metabolic Genes Oxytocin signaling pathway; FoxO signaling pathway; Hypertrophic cardiomyopathy (HCM); Insulin signaling pathway; Insulin resistance; Circadian rhythm; Longevity regulating pathway; Non-alcoholic fatty liver disease (NAFLD); Adipocytokine signaling pathway; AMPK signaling pathway; Glucagon signaling pathway; Longevity regulating pathway - multiple species 0 High Q922U1 U4/U6 small nuclear ribonucleoprotein Prp3 OS=Mus musculus OX=10090 GN=Prpf3 PE=1 SV=1 0 4.208 4 2 2 2 683 77.4 9.5 2 2 cell organization and biogenesis;metabolic process cytosol;nucleus;spliceosomal complex protein binding;RNA binding "Pf01480, Pf06544, Pf08572" 70767 ENSMUSG00000015748.13 Prpf3 3 mRNA Splicing - Major Pathway Spliceosome 0 High P80316 T-complex protein 1 subunit epsilon OS=Mus musculus OX=10090 GN=Cct5 PE=1 SV=1 0 8.826 5 1 2 1 541 59.6 6.02 1 1 1 1 193253.8594 530488.875 1568167.375 1 1 1 metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol nucleotide binding;protein binding;RNA binding Pf00118 12465 ENSMUSG00000022234.14 Cct5 15 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Association of TriC/CCT with target proteins during biosynthesis 0 High Q9D2R8 "28S ribosomal protein S33, mitochondrial OS=Mus musculus OX=10090 GN=Mrps33 PE=1 SV=1" 0 3.706 11 1 2 1 106 12.5 10.26 1 1 1 1 3729663.5 4110866.5 6391993.5 1 1 1 mitochondrion;ribosome Pf08293 14548 ENSMUSG00000029918.9 Mrps33 6 Mitochondrial translation termination; Mitochondrial translation elongation 0 High Q9D6I7 Divergent protein kinase domain 1A OS=Mus musculus OX=10090 GN=Dipk1a PE=2 SV=1 0 9.165 10 2 2 2 428 48.9 7.03 2 2 4862613 2 endoplasmic reticulum;membrane protein binding "Pf12260, Pf14875" 67266 ENSMUSG00000029270.10 Fam69a 5 0 High Q9WV55 Vesicle-associated membrane protein-associated protein A OS=Mus musculus OX=10090 GN=Vapa PE=1 SV=2 0.004 2.458 6 2 2 2 249 27.8 8.4 2 2 cell death;cell organization and biogenesis;regulation of biological process;response to stimulus;transport cytoskeleton;endoplasmic reticulum;membrane;nucleus protein binding;signal transducer activity Pf00635 30960 ENSMUSG00000024091.8 Vapa 17 Neutrophil degranulation; Sphingolipid de novo biosynthesis Tight junction 0 High P14152 "Malate dehydrogenase, cytoplasmic OS=Mus musculus OX=10090 GN=Mdh1 PE=1 SV=3" 0 7.945 9 2 2 2 334 36.5 6.58 2 2 2132787.688 1813708.5 3804363.5 2 1 1 metabolic process cytoplasm;cytosol;mitochondrion catalytic activity;nucleotide binding "Pf00056, Pf02866" 17449 ENSMUSG00000020321.15 Mdh1 11 Gluconeogenesis Pyruvate metabolism; Citrate cycle (TCA cycle); Metabolic pathways; Cysteine and methionine metabolism; Proximal tubule bicarbonate reclamation; Carbon metabolism; Glyoxylate and dicarboxylate metabolism 0 High Q8BR37 E3 ubiquitin-protein ligase NHLRC1 OS=Mus musculus OX=10090 GN=Nhlrc1 PE=2 SV=1 0 4.284 7 2 2 2 401 42.7 7.31 2 2 2638750.375 2 Met-loss+Acetyl [N-Term] metabolic process;regulation of biological process endoplasmic reticulum;nucleus catalytic activity;metal ion binding;protein binding 105193 ENSMUSG00000044231.2 Nhlrc1 13 Glycogen synthesis Ubiquitin mediated proteolysis 0 High A0A494B9P4 WD repeat-containing protein 7 OS=Mus musculus OX=10090 GN=Wdr7 PE=1 SV=1 0.003 3.081 3 1 2 1 488 53.8 6.13 1 1 1 1 116515.1094 315087.1875 1 1 Met-loss+Acetyl [N-Term] 0 High A0A338P6X2 Protein FAM162A OS=Mus musculus OX=10090 GN=Fam162a PE=1 SV=1 0 5.497 31 2 2 2 64 7.2 9.92 2 2 11985066 2 0 High Q921M3 Splicing factor 3B subunit 3 OS=Mus musculus OX=10090 GN=Sf3b3 PE=1 SV=1 0 3.741 1 2 2 2 1217 135.5 5.26 2 2 288602.5938 5887563.5 1 2 metabolic process;regulation of biological process nucleus;spliceosomal complex protein binding;RNA binding "Pf03178, Pf10433" 101943 ENSMUSG00000033732.10 Sf3b3 8 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway Spliceosome 0 High Q9CPP6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 OS=Mus musculus OX=10090 GN=Ndufa5 PE=1 SV=3 0.007 1.877 6 1 2 1 116 13.4 8.1 1 1 1 1 983466.3125 3917907.5 1 1 cell organization and biogenesis;metabolic process;transport membrane;mitochondrion catalytic activity Pf04716 68202 ENSMUSG00000023089.12 Ndufa5 6 Complex I biogenesis 0 High Q8BTZ5 Ankyrin repeat domain-containing protein 46 OS=Mus musculus OX=10090 GN=Ankrd46 PE=1 SV=1 0 8.403 12 2 2 2 228 25.2 5.73 2 2 5453672.5 1 membrane protein binding "Pf00023, Pf12796, Pf13606, Pf13637, Pf13857" 68839 ENSMUSG00000048307.7 Ankrd46 15 0 High A0A0R4J039 Histidine-rich glycoprotein OS=Mus musculus OX=10090 GN=Hrg PE=1 SV=1 0.006 2.248 7 2 2 2 536 60.4 7.61 1 1 1 1 357374.1563 251348.3594 1 1 coagulation;defense response;regulation of biological process;response to stimulus;transport cell surface;endosome;extracellular;membrane;vacuole enzyme regulator activity;metal ion binding;protein binding 94175 ENSMUSG00000022877.8 Hrg 16 Dissolution of Fibrin Clot; Platelet degranulation 0 High E9PUD2 Dynamin-1-like protein OS=Mus musculus OX=10090 GN=Dnm1l PE=1 SV=1 0 4.604 3 2 2 2 712 79.5 7.08 2 2 1298906.469 2 Acetyl [N-Term] cell death;cell organization and biogenesis;regulation of biological process;transport cytoplasm;cytoskeleton;cytosol;endoplasmic reticulum;Golgi;membrane;mitochondrion catalytic activity;nucleotide binding;protein binding "Pf00350, Pf01031, Pf02212" 74006 ENSMUSG00000022789.14 Dnm1l 16 0 High D3Z4A4 Peroxiredoxin-2 (Fragment) OS=Mus musculus OX=10090 GN=Prdx2 PE=1 SV=8 0.009 1.803 5 1 2 1 146 16 5.53 1 1 1 1 1591292 1834112.875 4595389 1 1 1 cell proliferation;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus mitochondrion antioxidant activity;catalytic activity "Pf00578, Pf08534" ENSMUSG00000005161.15 8 0 High Q91W59 "RNA-binding motif, single-stranded-interacting protein 1 OS=Mus musculus OX=10090 GN=Rbms1 PE=1 SV=1" 0.003 3.015 4 1 2 1 403 44 8.66 1 2 1129530.375 1 metabolic process nucleus DNA binding;RNA binding "Pf00076, Pf13893, Pf14259" 56878 ENSMUSG00000026970.16 Rbms1 2 0 High P54822 Adenylosuccinate lyase OS=Mus musculus OX=10090 GN=Adsl PE=1 SV=2 0 4.137 5 2 2 2 484 54.8 7.27 2 2 2918296.813 2955156.5 2 1 cell organization and biogenesis;metabolic process;response to stimulus cytosol;mitochondrion catalytic activity "Pf00206, Pf10397" 11564 ENSMUSG00000022407.9 Adsl 15 Purine ribonucleoside monophosphate biosynthesis "Metabolic pathways; Purine metabolism; Alanine, aspartate and glutamate metabolism" 0 Medium P62082 40S ribosomal protein S7 OS=Mus musculus OX=10090 GN=Rps7 PE=2 SV=1 0.016 1.468 4 1 2 1 194 22.1 10.1 1 2 1598671 3041617.5 4066405.5 2916971.25 1 1 1 1 cell differentiation;metabolic process;regulation of biological process cytoplasm;cytoskeleton;membrane;nucleus;ribosome protein binding;RNA binding;structural molecule activity Pf01251 20115 ENSMUSG00000061477.3 Rps7 12 "L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" Ribosome 0 High Q9QXK7 Cleavage and polyadenylation specificity factor subunit 3 OS=Mus musculus OX=10090 GN=Cpsf3 PE=1 SV=2 0 3.778 3 2 2 2 684 77.5 5.6 1 1 1 1 1268381.125 4808608.875 1459032.375 2 2 1 metabolic process nucleus catalytic activity;metal ion binding;RNA binding "Pf00753, Pf07521, Pf10996, Pf11718, Pf12706, Pf13483" 54451 ENSMUSG00000054309.8 Cpsf3 12 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Processing of Intronless Pre-mRNAs; Cleavage of Growing Transcript in the Termination Region mRNA surveillance pathway 0 Medium Q99LX0 Parkinson disease protein 7 homolog OS=Mus musculus OX=10090 GN=Park7 PE=1 SV=1 0.01 1.7 4 1 2 1 189 20 6.77 1 1 1 1 625210.125 4636893.5 1 1 cell communication;cell organization and biogenesis;cell proliferation;defense response;metabolic process;regulation of biological process;response to stimulus;transport chromosome;cytoplasm;cytosol;endoplasmic reticulum;membrane;mitochondrion;nucleus;organelle lumen antioxidant activity;catalytic activity;enzyme regulator activity;metal ion binding;protein binding;RNA binding "Pf01965, Pf13278" 57320 ENSMUSG00000028964.14 Park7 4 Parkinson's disease 0 High P48722 Heat shock 70 kDa protein 4L OS=Mus musculus OX=10090 GN=Hspa4l PE=1 SV=2 0 6.157 4 2 2 2 838 94.3 5.74 2 2 1930734.25 1 metabolic process;response to stimulus cytoplasm;cytosol;nucleus nucleotide binding;protein binding Pf00012 18415 ENSMUSG00000025757.12 Hspa4l 3 Protein processing in endoplasmic reticulum 0 Low P17426 AP-2 complex subunit alpha-1 OS=Mus musculus OX=10090 GN=Ap2a1 PE=1 SV=1 0.074 0.845 1 1 2 1 977 107.6 7.03 1 2 13774618.75 24831095 24787774.5 24471446 1 1 1 1 regulation of biological process;transport membrane protein binding;transporter activity "Pf01602, Pf02296, Pf02883, Pf13646" 11771 ENSMUSG00000060279.14 Ap2a1 7 "WNT5A-dependent internalization of FZD4; Trafficking of GluR2-containing AMPA receptors; VLDLR internalisation and degradation; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Recycling pathway of L1; MHC class II antigen presentation; Cargo recognition for clathrin-mediated endocytosis; LDL clearance" Endocytosis; Endocrine and other factor-regulated calcium reabsorption; Huntington's disease; Synaptic vesicle cycle 0 High Q922Q1 Mitochondrial amidoxime reducing component 2 OS=Mus musculus OX=10090 GN=Mtarc2 PE=1 SV=1 0.003 2.916 4 2 2 2 338 38.2 8.68 2 2 8528967 1 metabolic process membrane;mitochondrion catalytic activity;metal ion binding "Pf03473, Pf03476" 67247 ENSMUSG00000073481.9 Marc2; Mosc2 1 Phase I - Functionalization of compounds 0 High Q8BH73 Glutaminyl-peptide cyclotransferase-like protein OS=Mus musculus OX=10090 GN=Qpctl PE=1 SV=1 0 7.679 6 2 2 2 383 42.7 9.29 2 2 metabolic process Golgi;membrane catalytic activity;metal ion binding Pf04389 67369 ENSMUSG00000030407.2 Qpctl 7 0 High Q8VE95 UPF0598 protein C8orf82 homolog OS=Mus musculus OX=10090 PE=1 SV=1 0 4.843 12 2 2 2 218 24.3 8.7 2 2 620984.7031 260447.2969 189349.1719 6032886.625 2 1 1 2 regulation of biological process mitochondrion Pf14956 223665 ENSMUSG00000033707.8 C030006K11Rik 15 0 High Q78IK4 MICOS complex subunit Mic27 OS=Mus musculus OX=10090 GN=Apool PE=1 SV=1 0 9.367 10 2 2 2 265 29.2 9.31 2 2 1150846.875 8023704 2 2 cell organization and biogenesis membrane;mitochondrion Pf09769 68117 ENSMUSG00000025525.12 Apool X Platelet degranulation 0 High P22315 "Ferrochelatase, mitochondrial OS=Mus musculus OX=10090 GN=Fech PE=1 SV=2" 0.001 3.518 5 2 2 2 420 47.1 8.91 1 1 1 1 810938.8281 7087300.75 2 2 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion catalytic activity;metal ion binding;protein binding;RNA binding Pf00762 14151 Fech 18 0 High Q9CZB0 "Succinate dehydrogenase cytochrome b560 subunit, mitochondrial OS=Mus musculus OX=10090 GN=Sdhc PE=1 SV=1" 0 6.82 17 2 2 2 169 18.4 9.94 2 2 710109.375 4520646 1 1 metabolic process;transport membrane;mitochondrion catalytic activity;metal ion binding Pf01127 66052 ENSMUSG00000058076.12 Sdhc 1 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Carbon metabolism 0 High A0A4P8DYG6 Calsyntenin 3beta OS=Mus musculus OX=10090 GN=Clstn3 PE=2 SV=1 0 5.767 6 1 2 1 357 39.5 9.2 1 1 1 1 0 High B1AQH6 Mediator of RNA polymerase II transcription subunit 1 OS=Mus musculus OX=10090 GN=Med1 PE=1 SV=1 0 4.041 3 2 2 2 629 70.1 7.72 2 2 1872349.063 2686877.625 927052.875 2 2 1 cell differentiation;cell organization and biogenesis;cell proliferation;development;metabolic process;regulation of biological process;response to stimulus;transport chromosome;membrane;nucleus catalytic activity;DNA binding;protein binding;receptor activity Pf10744 19014 ENSMUSG00000018160.15 Med1 11 0 High Q6A0A9 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Mus musculus OX=10090 GN=FAM120A PE=1 SV=2 0 4.503 3 2 2 2 1112 121.6 8.92 2 2 1892752.813 1425012 2 1 cytoplasm;cytosol;membrane;nucleus RNA binding Pf13458 218236 ENSMUSG00000038014.7 Fam120a 13 0 High Q8VBZ3 Cleft lip and palate transmembrane protein 1 homolog OS=Mus musculus OX=10090 GN=Clptm1 PE=1 SV=1 0 10.249 4 1 2 1 664 75.2 6.3 1 2 cell differentiation;development;regulation of biological process membrane Pf05602 56457 ENSMUSG00000002981.10 Clptm1 7 0 High Q9CRA9 FGFR1 oncogene partner 2 homolog OS=Mus musculus OX=10090 GN=Fgfr1op2 PE=1 SV=1 0.003 2.984 5 1 2 1 253 29.4 5.83 1 1 1 1 Met-loss+Acetyl [N-Term] response to stimulus cytoplasm protein binding "Pf05769, Pf11262" 67529 ENSMUSG00000040242.14 Fgfr1op2 6 0 High Q9Z329 "Inositol 1,4,5-trisphosphate receptor type 2 OS=Mus musculus OX=10090 GN=Itpr2 PE=1 SV=4" 0 4.123 1 2 2 2 2701 307.3 6.44 1 1 1 1 115739.4688 627539.375 404905.9063 1 1 1 cellular homeostasis;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;membrane;nucleus metal ion binding;protein binding;receptor activity;signal transducer activity;transporter activity "Pf01365, Pf02815, Pf08454, Pf08709, Pf12670" 16439 ENSMUSG00000030287.15 Itpr2 6 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Ion homeostasis; Effects of PIP2 hydrolysis; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Gastrin-CREB signalling pathway via PKC and MAPK; Elevation of cytosolic Ca2+ levels Oxytocin signaling pathway; Cholinergic synapse; Retrograde endocannabinoid signaling; Pancreatic secretion; Dopaminergic synapse; NOD-like receptor signaling pathway; Long-term potentiation; Platelet activation; Thyroid hormone synthesis; Oocyte meiosis; Glutamatergic synapse; Proteoglycans in cancer; Long-term depression; cGMP-PKG signaling pathway; Calcium signaling pathway; Salivary secretion; Alzheimer's disease; Vascular smooth muscle contraction; Aldosterone synthesis and secretion; GnRH signaling pathway; Gastric acid secretion; Renin secretion; Gap junction; Estrogen signaling pathway; Glucagon signaling pathway; Phosphatidylinositol signaling system; Serotonergic synapse; Inflammatory mediator regulation of TRP channels; Apoptosis 0 Medium Q7TMG8 Glioblastoma amplified sequence OS=Mus musculus OX=10090 GN=Nipsnap2 PE=1 SV=1 0.021 1.331 3 1 2 1 281 32.9 9.33 1 2 1754366 3036587.5 3450632.5 1 1 1 metabolic process;regulation of biological process cytoplasm;membrane;mitochondrion Pf07978 14467 ENSMUSG00000029432.12 Gbas; Nipsnap2 5 0 High Q922Q8 Leucine-rich repeat-containing protein 59 OS=Mus musculus OX=10090 GN=Lrrc59 PE=1 SV=1 0 8.176 8 2 2 2 307 34.9 9.52 2 2 337466.25 3020170.75 1204024.75 8489713 1 2 1 2 endoplasmic reticulum;membrane;nucleus protein binding;RNA binding "Pf12799, Pf13855" 98238 ENSMUSG00000020869.8 Lrrc59 11 0 High B2RSU6 Cingulin-like 1 OS=Mus musculus OX=10090 GN=Cgnl1 PE=1 SV=1 0 5.905 3 2 2 2 1297 148.1 5.77 2 2 cell differentiation;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;Golgi catalytic activity;motor activity;protein binding;structural molecule activity;transporter activity "Pf00038, Pf00261, Pf00769, Pf01496, Pf01576, Pf02463, Pf03961, Pf03962, Pf04094, Pf04111, Pf04156, Pf05262, Pf05483, Pf05557, Pf05622, Pf05667, Pf05701, Pf05911, Pf06008, Pf06160, Pf06548, Pf06785, Pf06810, Pf07111, Pf07888, Pf07946, Pf09726, Pf09730, Pf10174, Pf12128, Pf13166, Pf13514, Pf13654, Pf13851, Pf13863, Pf13868, Pf15070, Pf15450, Pf15619" 68178 ENSMUSG00000032232.14 Cgnl1 9 0 High A2AVJ7 Ribosome-binding protein 1 OS=Mus musculus OX=10090 GN=Rrbp1 PE=1 SV=1 0.001 3.623 10 1 2 1 1464 158.3 9.19 1 1 1 1 2637619.25 1 cell differentiation;metabolic process;regulation of biological process;transport endoplasmic reticulum;membrane;ribosome protein binding;receptor activity;RNA binding;structural molecule activity "Pf00038, Pf03276, Pf03962, Pf04111, Pf04156, Pf05104, Pf08317, Pf09606, Pf09726, Pf10186, Pf12128, Pf13779" 81910 ENSMUSG00000027422.15 Rrbp1 2 Protein processing in endoplasmic reticulum 0 High A0A075B5W6 Immunoglobulin heavy variable 1-55 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-55 PE=1 SV=1 0 11.096 21 1 2 1 117 12.7 8.27 1 1 1 1 3598682.75 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding Pf07686 ENSMUSG00000095589.2 12 0 High Q9Z0N1 "Eukaryotic translation initiation factor 2 subunit 3, X-linked OS=Mus musculus OX=10090 GN=Eif2s3x PE=1 SV=2" 0 6.22 5 2 2 2 472 51 8.4 2 2 metabolic process cytoplasm catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00009, Pf03144, Pf09173" 26905 ENSMUSG00000035150.15 Eif2s3x X "L13a-mediated translational silencing of Ceruloplasmin expression; Recycling of eIF2:GDP; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ABC-family proteins mediated transport; Formation of the ternary complex, and subsequently, the 43S complex; Translation initiation complex formation" RNA transport 0 High F8WH20 Oxysterol-binding protein OS=Mus musculus OX=10090 GN=Osbpl3 PE=1 SV=1 0.009 1.799 1 1 2 1 819 93 6.54 1 2 1333509.5 2145756.25 1 1 transport cytoplasm;cytosol;endoplasmic reticulum;membrane;nucleus "Pf00169, Pf01237, Pf15409, Pf15413" 71720 ENSMUSG00000029822.15 Osbpl3 6 0 High Q8BZ03 Serine/threonine-protein kinase D2 OS=Mus musculus OX=10090 GN=Prkd2 PE=1 SV=1 0.007 2.041 2 1 2 1 875 96.5 6.89 1 2 709031.8125 1 cell death;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;Golgi;membrane;nucleus catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00069, Pf00130, Pf00169, Pf07714, Pf14531" 101540 ENSMUSG00000041187.16 Prkd2 7 Sphingolipid de novo biosynthesis Rap1 signaling pathway; Aldosterone synthesis and secretion 0 High Q8BTV2 Cleavage and polyadenylation specificity factor subunit 7 OS=Mus musculus OX=10090 GN=Cpsf7 PE=1 SV=2 0 4.094 5 1 2 1 471 52 8 1 1 1 1 264507.6875 284911.7188 1 1 cell organization and biogenesis;metabolic process membrane;nucleus RNA binding "Pf00076, Pf14259" 269061 ENSMUSG00000034820.3 Cpsf7 19 mRNA Splicing - Major Pathway; mRNA 3'-end processing; Processing of Intronless Pre-mRNAs; Cleavage of Growing Transcript in the Termination Region mRNA surveillance pathway 0 High Q9CQB2 MAPK regulated corepressor interacting protein 2 OS=Mus musculus OX=10090 GN=Mcrip2 PE=1 SV=1 0.003 3.093 31 2 2 2 160 17.9 7.3 2 2 1468371.75 2 cytoplasm;nucleus protein binding Pf14799 68241 ENSMUSG00000025732.5 Fam195a; Mcrip2 17 0 High A0A1D5RLZ5 Phospholipase A2 group XV OS=Mus musculus OX=10090 GN=Pla2g15 PE=1 SV=1 0 4.309 8 2 2 2 236 26.5 7.97 2 2 metabolic process extracellular;membrane;mitochondrion;vacuole catalytic activity Pf02450 192654 ENSMUSG00000031903.7 Pla2g15 8 0 High B1AZI6 THO complex subunit 2 OS=Mus musculus OX=10090 GN=Thoc2 PE=1 SV=1 0 5.899 1 2 2 2 1594 182.7 8.44 2 2 cell differentiation;cell division;cell organization and biogenesis;metabolic process;regulation of biological process;transport nucleus protein binding;RNA binding "Pf11262, Pf11732" 331401 ENSMUSG00000037475.15 Thoc2 X mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript Spliceosome; RNA transport 0 High F7CBX2 Uridine/cytidine kinase (Fragment) OS=Mus musculus OX=10090 GN=Uck1 PE=1 SV=1 0 5.871 11 2 2 2 208 23.4 7.5 2 2 636958.75 1422772.75 1 1 metabolic process catalytic activity;nucleotide binding Pf00485 ENSMUSG00000002550.16 2 Pyrimidine salvage 0 High P27046 Alpha-mannosidase 2 OS=Mus musculus OX=10090 GN=Man2a1 PE=1 SV=2 0.001 3.615 3 2 2 1 1150 131.5 8.03 2 2 cell organization and biogenesis;metabolic process;regulation of biological process Golgi;membrane catalytic activity;metal ion binding "Pf01074, Pf03065, Pf07748, Pf09261" 17158 ENSMUSG00000024085.13 Man2a1 17 Reactions specific to the complex N-glycan synthesis pathway Metabolic pathways; N-Glycan biosynthesis 0 High P62309 Small nuclear ribonucleoprotein G OS=Mus musculus OX=10090 GN=Snrpg PE=1 SV=1 0 3.723 26 2 2 2 76 8.5 8.88 2 2 2346381.25 5851985 7631591 1 1 1 cell organization and biogenesis;metabolic process cytoplasm;cytosol;nucleus;spliceosomal complex RNA binding;structural molecule activity "Pf01423, Pf03122" 68011 ENSMUSG00000049124.3; ENSMUSG00000057278.8 Snrpg 6; 17 mRNA Splicing - Minor Pathway; Cleavage of Growing Transcript in the Termination Region ; mRNA Splicing - Major Pathway; snRNP Assembly; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs; SLBP independent Processing of Histone Pre-mRNAs Spliceosome 0 High A0A0R4J094 Fumarylacetoacetate hydrolase domain-containing 2A OS=Mus musculus OX=10090 GN=Fahd2a PE=1 SV=1 0.003 2.818 4 1 2 1 313 34.7 8.16 1 2 1139770.75 1 metabolic process mitochondrion catalytic activity;metal ion binding Pf01557 68126 ENSMUSG00000027371.10 Fahd2a 2 0 High A0A075B6A7 Immunoglobulin heavy variable 2-6 (Fragment) OS=Mus musculus OX=10090 GN=Ighv2-6 PE=4 SV=1 0 5.675 14 1 2 1 116 12.6 8.48 1 1 1 1 1507740.75 1494351.75 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000096670.1 LOC674132 12 0 High A0A1L1SV25 Alpha-actinin-4 OS=Mus musculus OX=10090 GN=Actn4 PE=1 SV=1 0.003 3.111 3 2 2 2 932 107 5.36 2 2 319019.125 1 metal ion binding;protein binding "Pf00307, Pf00435, Pf08726, Pf11971, Pf13499, Pf13833" ENSMUSG00000054808.15 7 0 High Q3TWZ5 Thioredoxin domain-containing protein 11 OS=Mus musculus OX=10090 GN=Txndc11 PE=1 SV=1 0.001 3.545 4 2 2 2 639 70.4 7.31 2 2 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;membrane catalytic activity "Pf00085, Pf13905" 106200 ENSMUSG00000022498.16 Txndc11 16 0 High P03930 ATP synthase protein 8 OS=Mus musculus OX=10090 GN=Mtatp8 PE=1 SV=1 0.004 2.38 15 1 2 1 67 7.8 9.88 1 2 2059762 13673187 1 1 metabolic process;response to stimulus;transport membrane;mitochondrion catalytic activity;transporter activity Pf00895 17706; 3338900 ENSMUSG00000064356.3 ATP8 MT Cristae formation; Formation of ATP by chemiosmotic coupling Metabolic pathways; Huntington's disease; Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 Medium I7HJS4 Tissue-resident T-cell transcription regulator protein ZNF683 OS=Mus musculus OX=10090 GN=Znf683 PE=2 SV=1 0.043 1.038 2 1 2 1 458 50.4 8.92 1 2 686920.875 1 cell differentiation;defense response;metabolic process;regulation of biological process;response to stimulus nucleus DNA binding;metal ion binding "Pf00096, Pf13465" 100503878 ENSMUSG00000049410.8 Zfp683 4 0 High P53986 Monocarboxylate transporter 1 OS=Mus musculus OX=10090 GN=Slc16a1 PE=1 SV=1 0 5.168 7 2 2 2 493 53.2 7.47 2 2 998450.8125 3565598.25 33006720 1 1 2 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport membrane;mitochondrion protein binding;transporter activity "Pf00083, Pf07690" 20501 ENSMUSG00000032902.1 Slc16a1 3 Basigin interactions; Proton-coupled monocarboxylate transport; Pyruvate metabolism 0 High Q8CGC7 Bifunctional glutamate/proline--tRNA ligase OS=Mus musculus OX=10090 GN=Eprs1 PE=1 SV=4 0 3.76 2 2 2 2 1512 170 7.66 1 1 1 1 352842.125 2765535.25 1 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane catalytic activity;metal ion binding;nucleotide binding;protein binding;RNA binding "Pf00458, Pf00587, Pf00749, Pf01406, Pf03129, Pf03950, Pf09180, Pf14497" 107508 ENSMUSG00000026615.14 Eprs 1 Metabolic pathways; Aminoacyl-tRNA biosynthesis; Porphyrin and chlorophyll metabolism 0 High Z4YJS5 Agrin OS=Mus musculus OX=10090 GN=Agrn PE=1 SV=1 0 7.3 3 2 2 2 1151 121.8 5.44 2 2 cell communication;cell differentiation;cell organization and biogenesis;development;metabolic process;regulation of biological process;transport cell surface;cytosol;membrane enzyme regulator activity;metal ion binding;protein binding;transporter activity "Pf00050, Pf00053, Pf01390, Pf03137, Pf07648" 11603 ENSMUSG00000041936.18 Agrn 4 0 High Q8QZS1 "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Mus musculus OX=10090 GN=Hibch PE=1 SV=1" 0 5.389 9 2 2 2 385 43 8.06 1 1 1 1 874018.6875 1488339.625 1 1 metabolic process mitochondrion catalytic activity "Pf00378, Pf13766" 227095 ENSMUSG00000041426.12 Hibch 1 Branched-chain amino acid catabolism "Valine, leucine and isoleucine degradation; Metabolic pathways; beta-Alanine metabolism; Propanoate metabolism; Carbon metabolism" 0 Medium Q6VGS5 Protein Daple OS=Mus musculus OX=10090 GN=Ccdc88c PE=1 SV=1 0.023 1.293 0 1 2 1 2009 226.4 6.15 1 1 1 1 5906560 10829724 12925027 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol protein binding "Pf02463, Pf03938, Pf03962, Pf04111, Pf04156, Pf05557, Pf05622, Pf12128" 68339 ENSMUSG00000021182.14 Ccdc88c 12 0 High G5E866 Splicing factor 3B subunit 1 OS=Mus musculus OX=10090 GN=Sf3b1 PE=1 SV=1 0 7.154 2 1 2 1 1304 145.7 7.09 1 1 1 1 33910.82422 146502.75 305170.5625 318874.3438 1 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus chromosome;nucleus;spliceosomal complex DNA binding;protein binding;receptor activity;RNA binding;signal transducer activity "Pf02161, Pf08920, Pf12815, Pf13513" 81898 ENSMUSG00000025982.13 Sf3b1 1 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; B-WICH complex positively regulates rRNA expression Spliceosome 0 High A0A1B0GT04 Glutaredoxin-3 (Fragment) OS=Mus musculus OX=10090 GN=Glrx3 PE=1 SV=1 0 3.928 18 1 1 1 163 18.1 4.78 1 1 98835.28125 203996.1719 78322.03906 1 1 1 Met-loss+Acetyl [N-Term] cellular homeostasis;metabolic process;regulation of biological process spliceosomal complex catalytic activity "Pf00085, Pf00462, Pf02114, Pf02966, Pf13098, Pf13905" ENSMUSG00000031068.8 7 0 High Q9CXV1 "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial OS=Mus musculus OX=10090 GN=Sdhd PE=1 SV=2" 0.007 1.999 4 1 1 1 159 17 9.1 1 1 metabolic process;regulation of biological process;response to stimulus;transport membrane;mitochondrion catalytic activity;metal ion binding Pf05328 66925 ENSMUSG00000000171.5 Sdhd 9 Citric acid cycle (TCA cycle) Citrate cycle (TCA cycle); Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease; Carbon metabolism 0 Medium A0A0X1KG67 ER membrane protein complex subunit 10 OS=Mus musculus OX=10090 GN=Emc10 PE=1 SV=1 0.016 1.473 3 1 1 1 268 28.2 6.55 1 1 extracellular;membrane 69683 ENSMUSG00000008140.17 Emc10 7 0 Low Q9D0I8 mRNA turnover protein 4 homolog OS=Mus musculus OX=10090 GN=Mrto4 PE=1 SV=1 0.066 0.909 10 1 1 1 239 27.5 8.54 1 1 cell organization and biogenesis;metabolic process cytoplasm;nucleus RNA binding Pf00466 69902 ENSMUSG00000028741.13 Mrto4 4 0 High A0A1B0GT63 Transmembrane protein 143 OS=Mus musculus OX=10090 GN=Tmem143 PE=1 SV=1 0 3.892 10 1 1 1 453 51 9.14 1 1 1168970.875 1 cell differentiation membrane;mitochondrion 70209 ENSMUSG00000002781.19 Tmem143 7 0 Medium P05208 Chymotrypsin-like elastase family member 2A OS=Mus musculus OX=10090 GN=Cela2a PE=1 SV=1 0.041 1.052 3 1 1 1 271 28.9 8.62 1 1 metabolic process extracellular catalytic activity Pf00089 13706 ENSMUSG00000058579.5 Cela2a 4 Formation of the cornified envelope Pancreatic secretion; Protein digestion and absorption 0 High O08715 "A-kinase anchor protein 1, mitochondrial OS=Mus musculus OX=10090 GN=Akap1 PE=1 SV=4" 0 4.149 3 1 1 1 857 92.1 5.02 1 1 regulation of biological process endoplasmic reticulum;membrane;mitochondrion;organelle lumen protein binding;RNA binding;structural molecule activity "Pf00013, Pf00567, Pf13014" 11640 ENSMUSG00000018428.15 Akap1 11 Factors involved in megakaryocyte development and platelet production 0 High A0A140LIZ5 26S proteasome AAA-ATPase subunit RPT3 OS=Mus musculus OX=10090 GN=Psmc4 PE=1 SV=1 0.004 2.613 5 1 1 1 387 43.5 5.26 1 1 metabolic process;regulation of biological process;response to stimulus cytoplasm catalytic activity;nucleotide binding;RNA binding "Pf00004, Pf00006, Pf00910, Pf01057, Pf01078, Pf05496, Pf07724, Pf07726, Pf07728, Pf13191" ENSMUSG00000030603.16 7 0 High O89112 Glutathione S-transferase LANCL1 OS=Mus musculus OX=10090 GN=Lancl1 PE=1 SV=1 0.001 3.601 3 1 1 1 399 45.3 7.77 1 1 503771.4375 1 regulation of biological process;response to stimulus cytoplasm;membrane metal ion binding;protein binding Pf05147 14768 ENSMUSG00000026000.16 Lancl1 1 0 Low A0A571BFA7 Protein FAM83H OS=Mus musculus OX=10090 GN=Fam83h PE=1 SV=1 0.069 0.889 0 1 1 1 1409 153.1 6.9 1 1 485622.875 1799687.875 1561493.125 4248092.5 1 1 1 1 0 High Q9JKX6 ADP-sugar pyrophosphatase OS=Mus musculus OX=10090 GN=Nudt5 PE=1 SV=1 0.004 2.583 4 1 1 1 218 24 5.48 1 1 364199.2188 5761757.5 1 1 cell organization and biogenesis;metabolic process nucleus catalytic activity;metal ion binding;protein binding;RNA binding Pf00293 53893 ENSMUSG00000025817.12 Nudt5 2 Phosphate bond hydrolysis by NUDT proteins Purine metabolism 0 High O35492 Dual specificity protein kinase CLK3 OS=Mus musculus OX=10090 GN=Clk3 PE=1 SV=2 0 4.315 3 1 1 1 638 73.8 9.94 1 1 metabolic process;regulation of biological process cytoplasm;cytoskeleton;membrane;nucleus catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00069, Pf07714" 102414 ENSMUSG00000032316.8 Clk3 9 0 Medium O88477 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Mus musculus OX=10090 GN=Igf2bp1 PE=1 SV=1 0.01 1.688 2 1 1 1 577 63.4 9.2 1 1 3801998.5 4543500 3144026.25 2037148.5 1 1 1 1 cell proliferation;regulation of biological process;transport cytoplasm;cytosol;nucleus RNA binding;translation regulator activity "Pf00013, Pf00076, Pf13014, Pf13893, Pf14259" 140486 ENSMUSG00000013415.9 Igf2bp1 11 MicroRNAs in cancer 0 High A0A286YDK2 Growth hormone-inducible transmembrane protein (Fragment) OS=Mus musculus OX=10090 GN=Ghitm PE=1 SV=1 0.003 3.026 5 1 1 1 198 21.7 9.91 1 1 1688638.75 16050069 1 1 0 High Q99KJ6 Beta-glucuronidase OS=Mus musculus OX=10090 GN=Gusb PE=1 SV=1 0.001 3.486 4 1 1 1 250 28.5 6 1 1 metabolic process endoplasmic reticulum;membrane;vacuole catalytic activity;protein binding Pf02837 110006 ENSMUSG00000025534.17 Gusb 5 0 Medium B2RY56 RNA-binding protein 25 OS=Mus musculus OX=10090 GN=Rbm25 PE=1 SV=2 0.015 1.52 2 1 1 1 838 99.5 6.32 1 1 1877838.375 3962302.5 31311916 1 1 1 cell death;metabolic process;regulation of biological process cytoplasm;nucleus;spliceosomal complex RNA binding "Pf00076, Pf01480, Pf14259" 67039 ENSMUSG00000010608.15 Rbm25 12 Spliceosome 0 High B7ZNK6 Aga protein OS=Mus musculus OX=10090 GN=Aga PE=1 SV=1 0.004 2.636 4 1 1 1 336 35.9 5.95 1 1 5728861 1 metabolic process endoplasmic reticulum;vacuole catalytic activity;protein binding Pf01112 11593 ENSMUSG00000031521.5 Aga 8 0 Low Q9D1R2 Protein KTI12 homolog OS=Mus musculus OX=10090 GN=Kti12 PE=1 SV=1 0.073 0.875 5 1 1 1 351 38.4 6.92 1 1 nucleotide binding Pf08433 100087 ENSMUSG00000073775.4 Kti12 4 0 High Q3UBX0 Transmembrane protein 109 OS=Mus musculus OX=10090 GN=Tmem109 PE=1 SV=2 0.003 3.098 4 1 1 1 243 26.3 9.89 1 1 1782126.5 7305974.5 1 1 regulation of biological process;response to stimulus;transport endoplasmic reticulum;membrane;nucleus protein binding;transporter activity Pf14965 68539 ENSMUSG00000034659.14 Tmem109 19 0 Medium Q61235 Beta-2-syntrophin OS=Mus musculus OX=10090 GN=Sntb2 PE=1 SV=2 0.017 1.382 1 1 1 1 520 56.3 8.69 1 1 cytoplasm;cytoskeleton;membrane protein binding;RNA binding;structural molecule activity "Pf00169, Pf00595, Pf13180" 20650 ENSMUSG00000041308.6 Sntb2 8 0 Low E9Q9J5 "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (Fragment) OS=Mus musculus OX=10090 GN=Ndufb8 PE=1 SV=8" 0.055 0.979 7 1 1 1 138 15.6 7.61 1 1 388980.9063 1 metabolic process mitochondrion catalytic activity Pf05821 ENSMUSG00000025204.10 19 0 High Q8CCF0 U4/U6 small nuclear ribonucleoprotein Prp31 OS=Mus musculus OX=10090 GN=Prpf31 PE=1 SV=3 0 4.308 3 1 1 1 499 55.4 5.67 1 1 cell organization and biogenesis;metabolic process nucleus;spliceosomal complex RNA binding "Pf01798, Pf08060, Pf09785" 68988 ENSMUSG00000008373.16 Prpf31 7 mRNA Splicing - Major Pathway Spliceosome 0 Low Q9DCF9 Translocon-associated protein subunit gamma OS=Mus musculus OX=10090 GN=Ssr3 PE=1 SV=1 0.078 0.805 3 1 1 1 185 21.1 9.61 1 1 6558.473633 39500.83984 560705.75 1 1 1 cell organization and biogenesis;transport endoplasmic reticulum;membrane Pf07074 67437 ENSMUSG00000027828.12 Ssr3 3 Protein processing in endoplasmic reticulum 0 Medium Q9CXU1 Mediator of RNA polymerase II transcription subunit 31 OS=Mus musculus OX=10090 GN=Med31 PE=1 SV=2 0.015 1.518 5 1 1 1 131 15.8 8.54 1 1 611866.0625 1 metabolic process;regulation of biological process nucleus catalytic activity;protein binding Pf05669 67279 ENSMUSG00000020801.8 Med31 11 Generic Transcription Pathway; Mus musculus biological processes; Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes 0 High Q9QUH0 Glutaredoxin-1 OS=Mus musculus OX=10090 GN=Glrx PE=1 SV=3 0.007 1.949 8 1 1 1 107 11.9 8.37 1 1 355793.7813 1 Met-loss+Acetyl [N-Term] cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;mitochondrion;nucleus catalytic activity;protein binding "Pf00462, Pf13098, Pf13417" 93692 ENSMUSG00000021591.7 Glrx 13 Interconversion of nucleotide di- and triphosphates 0 Medium A0A0R4J023 "Methylglutaconyl-CoA hydratase, mitochondrial OS=Mus musculus OX=10090 GN=Auh PE=1 SV=1" 0.025 1.245 2 1 1 1 314 33.3 9.42 1 1 440367.9688 1 metabolic process mitochondrion catalytic activity;RNA binding Pf00378 11992 ENSMUSG00000021460.16 Auh 13 Branched-chain amino acid catabolism "Valine, leucine and isoleucine degradation; Metabolic pathways" 0 High Q9CXS4 Centromere protein V OS=Mus musculus OX=10090 GN=Cenpv PE=1 SV=2 0.004 2.609 8 1 1 1 252 27.5 9.79 1 1 419922.9063 1 cell division;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process chromosome;cytoplasm;cytoskeleton;cytosol;nucleus catalytic activity Pf04828 73139 ENSMUSG00000018509.8 Cenpv 11 0 High P56135 "ATP synthase subunit f, mitochondrial OS=Mus musculus OX=10090 GN=Atp5mf PE=1 SV=3" 0.007 1.953 11 1 1 1 88 10.3 9.95 1 1 295172.375 7226382.5 1 1 Met-loss+Acetyl [N-Term] metabolic process;transport membrane;mitochondrion;nucleus catalytic activity Pf10206 57423 ENSMUSG00000038690.15 Atp5j2 5 Cristae formation; Formation of ATP by chemiosmotic coupling Metabolic pathways; Oxidative phosphorylation 0 High Q91WD5 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Mus musculus OX=10090 GN=Ndufs2 PE=1 SV=1" 0.003 3.235 2 1 1 1 463 52.6 6.99 1 1 5285939.5 1 metabolic process;response to stimulus;transport membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding Pf00346 226646 ENSMUSG00000013593.12 Ndufs2 1 Complex I biogenesis Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High B1AUB9 Nuclear factor 1 OS=Mus musculus OX=10090 GN=Nfia PE=1 SV=1 0.004 2.47 5 1 1 1 487 53.6 9.01 1 1 Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process nucleus DNA binding;protein binding "Pf00859, Pf03165, Pf10524" 18027 ENSMUSG00000028565.18 Nfia 4 0 High A0A0A6YXA3 Immunoglobulin heavy variable V8-6 (Fragment) OS=Mus musculus OX=10090 GN=Ighv8-6 PE=4 SV=1 0.009 1.84 8 1 1 1 118 13.3 7.28 1 1 3059046.75 3653014 1 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000094505.2 12 Regulation of Complement cascade; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Cell surface interactions at the vascular wall; FCERI mediated NF-kB activation; Role of LAT2/NTAL/LAB on calcium mobilization; Role of phospholipids in phagocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR activation; Classical antibody-mediated complement activation; FCERI mediated Ca+2 mobilization; FCERI mediated MAPK activation; CD22 mediated BCR regulation; Scavenging of heme from plasma 0 High Q8R3N6 THO complex subunit 1 OS=Mus musculus OX=10090 GN=Thoc1 PE=1 SV=1 0.007 1.909 2 1 1 1 657 75.4 4.97 1 1 1804027.375 3640371.75 1672640.25 1 1 1 cell death;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;nucleus DNA binding;protein binding;RNA binding "Pf00531, Pf11957" 225160 ENSMUSG00000024287.7 Thoc1 18 mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript Spliceosome; RNA transport 0 High Q9CPZ8 COX assembly mitochondrial protein homolog OS=Mus musculus OX=10090 GN=Cmc1 PE=1 SV=1 0.003 3.296 10 1 1 1 106 12.5 8.24 1 1 1138628.625 4445903 1 1 Met-loss+Acetyl [N-Term] mitochondrion metal ion binding Pf08583 67899 ENSMUSG00000039163.10 Cmc1 9 0 High A0A3Q4EIF7 Ras-related protein Rab-18 OS=Mus musculus OX=10090 GN=Rab18 PE=1 SV=1 0.001 3.369 27 1 1 1 41 4.4 4.82 1 1 352416.875 8881125 1 1 0 High O70546 Lysine-specific demethylase 6A OS=Mus musculus OX=10090 GN=Kdm6a PE=1 SV=2 0.005 2.318 1 1 1 1 1401 154.3 7.39 1 1 855943.5625 1 cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus nucleus catalytic activity;DNA binding;metal ion binding;protein binding "Pf00515, Pf02373, Pf05109, Pf13414, Pf13424, Pf13431, Pf13432" 22289 ENSMUSG00000037369.16 Kdm6a X HDMs demethylate histones Transcriptional misregulation in cancer 0 Medium Q8R123 FAD synthase OS=Mus musculus OX=10090 GN=Flad1 PE=1 SV=1 0.034 1.102 1 1 1 1 492 54.7 6.64 1 1 370895.0313 1 metabolic process cytoplasm;cytosol;membrane catalytic activity;nucleotide binding "Pf00994, Pf01507" 319945 ENSMUSG00000042642.13 Flad1 3 Vitamin B2 (riboflavin) metabolism Metabolic pathways; Riboflavin metabolism 0 High Q61985 Endoplasmic reticulum membrane sensor NFE2L1 OS=Mus musculus OX=10090 GN=Nfe2l1 PE=1 SV=2 0.003 2.94 1 1 1 1 741 81.5 4.7 1 1 cell differentiation;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;endoplasmic reticulum;membrane;nucleus DNA binding;protein binding "Pf00170, Pf03131, Pf07716" 18023 ENSMUSG00000038615.17 Nfe2l1 11 0 High Q3TZA2 Cyclin-dependent kinase-like 4 OS=Mus musculus OX=10090 GN=Cdkl4 PE=2 SV=1 0.009 1.805 2 1 1 1 342 39.4 9.16 1 1 673270.25 1 metabolic process;regulation of biological process cytoplasm;nucleus catalytic activity;nucleotide binding "Pf00069, Pf01636, Pf07714" 381113 ENSMUSG00000033966.7 Cdkl4 17 0 High D3YU39 Cholinephosphotransferase 1 OS=Mus musculus OX=10090 GN=Chpt1 PE=1 SV=1 0 3.827 3 1 1 1 406 45.4 7.08 1 1 metabolic process Golgi;membrane catalytic activity;metal ion binding Pf01066 212862 ENSMUSG00000060002.14 Chpt1 10 0 Medium Q8K595 Mucolipin-2 OS=Mus musculus OX=10090 GN=Mcoln2 PE=1 SV=1 0.01 1.673 1 1 1 1 566 65.4 7.08 1 1 2318096.25 4637951 4324456 21207380 1 1 1 1 cell organization and biogenesis;cellular component movement;defense response;regulation of biological process;response to stimulus;transport endosome;membrane;vacuole transporter activity "Pf00520, Pf08016" 68279 ENSMUSG00000011008.13 Mcoln2 3 TRP channels 0 Medium A0A2I3BQZ9 Amyloid-beta A4 protein OS=Mus musculus OX=10090 GN=App PE=1 SV=1 0.041 1.054 1 1 1 1 751 84.6 4.79 1 1 3067544.75 4743827 3697599.25 6798640 1 1 1 1 0 High O88856 Protein-tyrosine sulfotransferase 2 OS=Mus musculus OX=10090 GN=Tpst2 PE=1 SV=1 0.001 3.463 3 1 1 1 376 42 9.35 1 1 2311362.25 3969272 1 1 cell organization and biogenesis;metabolic process;regulation of biological process endoplasmic reticulum;Golgi;membrane catalytic activity;protein binding "Pf00685, Pf04320, Pf13469" 22022 Tpst2 5 0 High Q91XX6 Protocadherin gamma B4 OS=Mus musculus OX=10090 GN=Pcdhgb4 PE=1 SV=1 0.007 1.879 2 1 1 1 912 99.2 5.01 1 1 2164324.5 2589228.5 1 1 cell communication membrane metal ion binding;protein binding "Pf00028, Pf08266" 93701 ENSMUSG00000103585.1 Pcdhgb4 18 0 Medium A0A338P6W9 ABI family member 3-binding protein OS=Mus musculus OX=10090 GN=Abi3bp PE=1 SV=1 0.031 1.148 1 1 1 1 884 97.2 9.54 1 1 30375168 18824578 16582265 21540118 1 1 1 1 0 High E9Q1G8 Septin OS=Mus musculus OX=10090 GN=Septin7 PE=1 SV=2 0.004 2.33 5 1 1 1 437 50.6 8.57 1 1 22413930 23729232 12590644 1 1 1 cell differentiation;cell division;cell growth;cell organization and biogenesis;regulation of biological process chromosome;cytoplasm;cytoskeleton;membrane;nucleus nucleotide binding;protein binding "Pf00735, Pf01926, Pf05368" 235072 ENSMUSG00000001833.17 Sept7 9 MAPK6/MAPK4 signaling 0 High E9Q0U7 Heat shock protein 105 kDa OS=Mus musculus OX=10090 GN=Hsph1 PE=1 SV=1 0.001 3.475 1 1 1 1 817 91.6 5.59 1 1 nucleotide binding Pf00012 ENSMUSG00000029657.15 5 0 Medium Q8BWJ3 "Phosphorylase b kinase regulatory subunit alpha, liver isoform OS=Mus musculus OX=10090 GN=Phka2 PE=1 SV=1" 0.021 1.322 1 1 1 1 1235 138.4 6.37 1 1 2185032.5 3323359 12171755 1 1 1 metabolic process membrane catalytic activity;protein binding Pf00723 110094 ENSMUSG00000031295.13 Phka2 X Glycogen breakdown (glycogenolysis) Insulin signaling pathway; Calcium signaling pathway; Glucagon signaling pathway 0 Medium Q9CR06 Aspartyl/asparaginyl beta-hydroxylase OS=Mus musculus OX=10090 GN=Asph PE=1 SV=1 0.012 1.593 4 1 1 1 207 22.7 9.77 1 1 13711.44629 62755.3125 100239.7969 1376066.375 1 1 1 1 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;endoplasmic reticulum;membrane catalytic activity;metal ion binding;protein binding Pf05279 65973 ENSMUSG00000028207.18 Asph 4 0 High Q9ERS2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 OS=Mus musculus OX=10090 GN=Ndufa13 PE=1 SV=3 0.003 2.755 9 1 1 1 144 16.8 9.48 1 1 cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;membrane;mitochondrion;nucleus catalytic activity;nucleotide binding Pf06212 67184 ENSMUSG00000036199.9 Ndufa13 8 Complex I biogenesis Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High O88829 "Lactosylceramide alpha-2,3-sialyltransferase OS=Mus musculus OX=10090 GN=St3gal5 PE=1 SV=2" 0.004 2.618 2 1 1 1 414 47.3 8.51 1 1 metabolic process Golgi;membrane catalytic activity Pf00777 20454 ENSMUSG00000056091.12 St3gal5 6 Sialic acid metabolism Metabolic pathways; Glycosphingolipid biosynthesis - ganglio series 0 High E0CZ30 "Myosin light chain 1/3, skeletal muscle isoform (Fragment) OS=Mus musculus OX=10090 GN=Myl1 PE=1 SV=1" 0.003 2.942 9 1 1 1 124 13.5 5.66 1 1 838735.9375 1 metal ion binding ENSMUSG00000061816.15 1 0 Medium Q05186 Reticulocalbin-1 OS=Mus musculus OX=10090 GN=Rcn1 PE=1 SV=1 0.026 1.208 6 1 1 1 325 38.1 4.84 1 1 693308.625 1 endoplasmic reticulum;organelle lumen metal ion binding Pf13499 19672 ENSMUSG00000005973.6 Rcn1 2 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation 0 High Q61001 Laminin subunit alpha-5 OS=Mus musculus OX=10090 GN=Lama5 PE=1 SV=4 0.009 1.834 0 1 1 1 3718 403.8 6.73 1 1 71546560 37696908 29804310 47181268 1 1 1 1 cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus;transport cytoplasm;extracellular;membrane;nucleus catalytic activity;motor activity;protein binding "Pf00052, Pf00053, Pf00054, Pf00055, Pf00529, Pf00769, Pf01576, Pf02210, Pf03302, Pf04156, Pf06008, Pf06009, Pf06188, Pf12718, Pf12795, Pf13514, Pf13779" 16776 ENSMUSG00000015647.9 Lama5 2 MET activates PTK2 signaling; Laminin interactions Focal adhesion; Toxoplasmosis; Metabolic pathways; Small cell lung cancer; Pathways in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway; Amoebiasis 0 Medium A0A1L1SQV7 Platelet-activating factor acetylhydrolase IB subunit alpha2 (Fragment) OS=Mus musculus OX=10090 GN=Pafah1b2 PE=1 SV=1 0.015 1.527 6 1 1 1 107 11.9 4.74 1 1 658821.125 1 Pf13472 ENSMUSG00000003131.7 9 0 High J3QP56 Acyl-protein thioesterase 1 OS=Mus musculus OX=10090 GN=Lypla1 PE=1 SV=1 0.009 1.843 5 1 1 1 224 23.7 7.06 1 1 994215.5 2731778 1 1 metabolic process;regulation of biological process cytoplasm;cytosol;mitochondrion catalytic activity "Pf00561, Pf02230, Pf03959, Pf07859, Pf12695, Pf12697" 18777 ENSMUSG00000025903.14 Lypla1 1 0 High P61166 Transmembrane protein 258 OS=Mus musculus OX=10090 GN=Tmem258 PE=1 SV=1 0.006 2.237 10 1 1 1 79 9.1 5.83 1 1 9121265 1 Acetyl [N-Term] metabolic process endoplasmic reticulum;membrane Pf05251 69038 ENSMUSG00000036372.14 1810006K21Rik; Tmem258 19 0 High Q8CHT0 "Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Aldh4a1 PE=1 SV=3" 0.003 2.706 3 1 1 1 562 61.8 8.24 1 1 1034797.563 1 cell organization and biogenesis;metabolic process mitochondrion;organelle lumen catalytic activity;protein binding "Pf00171, Pf06810" 212647 ENSMUSG00000028737.15 Aldh4a1 4 Proline catabolism; Glyoxylate metabolism and glycine degradation "Arginine and proline metabolism; Metabolic pathways; Alanine, aspartate and glutamate metabolism" 0 Medium Q9JMH6 "Thioredoxin reductase 1, cytoplasmic OS=Mus musculus OX=10090 GN=Txnrd1 PE=1 SV=3" 0.015 1.532 2 1 1 1 613 67 7.44 1 1 564362.125 1 cell organization and biogenesis;cell proliferation;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;mitochondrion;nucleus antioxidant activity;catalytic activity;metal ion binding;nucleotide binding;protein binding "Pf00070, Pf02852, Pf07992, Pf13738" 50493 ENSMUSG00000020250.10 Txnrd1 10 Interconversion of nucleotide di- and triphosphates; Metabolism of ingested MeSeO2H into MeSeH; Detoxification of Reactive Oxygen Species; TP53 Regulates Metabolic Genes Selenocompound metabolism; Pyrimidine metabolism 0 High F6RXI4 Chondroitin sulfate proteoglycan 4B OS=Mus musculus OX=10090 GN=Cspg4b PE=4 SV=2 0 5.232 1 1 1 1 2391 265.6 6.52 1 1 0 High Q99MR6 Serrate RNA effector molecule homolog OS=Mus musculus OX=10090 GN=Srrt PE=1 SV=1 0.006 2.071 1 1 1 1 875 100.4 5.97 1 1 2902065 1752430.625 1 1 cell proliferation;metabolic process;regulation of biological process cytoplasm;nucleus DNA binding;protein binding;RNA binding "Pf04959, Pf12066" 83701 ENSMUSG00000037364.11 Srrt 5 mRNA Splicing - Major Pathway; RNA polymerase II transcribes snRNA genes 0 High Q6NSR8 Probable aminopeptidase NPEPL1 OS=Mus musculus OX=10090 GN=Npepl1 PE=1 SV=1 0.003 3.043 2 1 1 1 524 55.9 6.84 1 1 603090.875 3217744.75 1 1 metabolic process cytoplasm;nucleus catalytic activity;metal ion binding Pf00883 228961 ENSMUSG00000039263.16 Npepl1 2 0 High E9QAT4 Protein transport protein Sec16A OS=Mus musculus OX=10090 GN=Sec16a PE=1 SV=1 0.006 2.15 2 1 1 1 2357 254 5.81 1 1 428773.8125 1 cell organization and biogenesis;transport cytosol;endoplasmic reticulum;Golgi;membrane catalytic activity "Pf10697, Pf12931, Pf12932" 227648 ENSMUSG00000026924.17 Sec16a 2 COPII (Coat Protein 2) Mediated Vesicle Transport 0 High Q9CQJ8 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 OS=Mus musculus OX=10090 GN=Ndufb9 PE=1 SV=3 0.01 1.752 5 1 1 1 179 22 7.8 1 1 cell organization and biogenesis;metabolic process;transport membrane;mitochondrion "Pf05347, Pf13232, Pf13233" 66218 ENSMUSG00000022354.3 Ndufb9 15 Complex I biogenesis Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High A2AIL4 "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 OS=Mus musculus OX=10090 GN=Ndufaf6 PE=1 SV=1" 0.003 3.272 6 1 1 1 333 38.3 9.44 1 1 cell organization and biogenesis;metabolic process cytoplasm;membrane;mitochondrion;nucleus catalytic activity Pf00494 76947 ENSMUSG00000050323.14 Ndufaf6 4 Complex I biogenesis 0 Medium Q8VDG5 Phosphopantothenate--cysteine ligase OS=Mus musculus OX=10090 GN=Ppcs PE=1 SV=1 0.017 1.377 2 1 1 1 311 33.8 6.55 1 1 2717319.75 3134523 1 1 metabolic process catalytic activity 106564 ENSMUSG00000028636.14 Ppcs 4 Coenzyme A biosynthesis Metabolic pathways; Pantothenate and CoA biosynthesis 0 High E9PXG5 Clusterin (Fragment) OS=Mus musculus OX=10090 GN=Clu PE=1 SV=1 0.004 2.583 7 1 1 1 233 26.9 6.64 1 1 802583.6875 1 regulation of biological process Pf01093 ENSMUSG00000022037.14 14 0 Medium F6WMD1 Alpha-2-macroglobulin receptor-associated protein (Fragment) OS=Mus musculus OX=10090 GN=Lrpap1 PE=1 SV=1 0.017 1.371 5 1 1 1 153 18.3 8.32 1 1 5071954.5 1 endoplasmic reticulum protein binding "Pf06400, Pf06401" ENSMUSG00000029103.16 5 0 Medium P07351 Interferon alpha-4 OS=Mus musculus OX=10090 GN=Ifna4 PE=3 SV=1 0.013 1.534 5 1 1 1 186 21.5 8.18 1 1 cell differentiation;cell proliferation;defense response;regulation of biological process;response to stimulus extracellular protein binding Pf00143 15967 ENSMUSG00000070904.4 Ifna4 4 Factors involved in megakaryocyte development and platelet production; Regulation of IFNA signaling; TRAF6 mediated IRF7 activation Herpes simplex infection; NOD-like receptor signaling pathway; Jak-STAT signaling pathway; RIG-I-like receptor signaling pathway; Tuberculosis; Hepatitis B; Toll-like receptor signaling pathway; Autophagy; Influenza A; Hepatitis C; Cytosolic DNA-sensing pathway; PI3K-Akt signaling pathway; Natural killer cell mediated cytotoxicity; Autoimmune thyroid disease; Cytokine-cytokine receptor interaction; Measles 0 Medium D3Z4Z0 Transcriptional adapter OS=Mus musculus OX=10090 GN=Tada2b PE=1 SV=1 0.016 1.441 2 1 1 1 420 48.5 7.83 1 1 1676533.125 2068608.375 1560495.125 2849326.75 1 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process nucleus catalytic activity;DNA binding;metal ion binding;protein binding "Pf00249, Pf04433, Pf13921" 231151 ENSMUSG00000029196.9 Tada2b 5 Ub-specific processing proteases 0 High G3UVU6 Mediator of RNA polymerase II transcription subunit 20 OS=Mus musculus OX=10090 GN=Gm20517 PE=3 SV=1 0.003 2.877 17 1 1 1 152 16.5 8 1 1 904281.5625 1 regulation of biological process Pf08612 ENSMUSG00000023984.17 17 Generic Transcription Pathway 0 High Q8VE80 THO complex subunit 3 OS=Mus musculus OX=10090 GN=Thoc3 PE=2 SV=1 0 6.338 9 1 1 1 351 38.7 6.09 1 1 Met-loss+Acetyl [N-Term] metabolic process;transport nucleus protein binding;RNA binding "Pf00400, Pf08662" 73666 ENSMUSG00000025872.5 Thoc3 13 mRNA 3'-end processing; Cleavage of Growing Transcript in the Termination Region ; Transport of Mature mRNA derived from an Intron-Containing Transcript Spliceosome; RNA transport 0 High F6TK14 Fibroblast growth factor receptor OS=Mus musculus OX=10090 GN=Fgfr3 PE=1 SV=1 0.003 2.724 1 1 1 1 801 87.7 6.32 1 1 cell communication;cell death;cell differentiation;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;endoplasmic reticulum;Golgi;membrane;nucleus;vacuole catalytic activity;nucleotide binding;protein binding;receptor activity;signal transducer activity "Pf00047, Pf00069, Pf07679, Pf07714, Pf13895, Pf13927" 14184 ENSMUSG00000054252.17 Fgfr3 5 "PI3K Cascade; Phospholipase C-mediated cascade; FGFR3; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; FRS-mediated FGFR3 signaling; SHC-mediated cascade:FGFR3; Interleukin-20 family signaling; Negative regulation of FGFR3 signaling; FRS-mediated FGFR2 signaling; RAF/MAP kinase cascade; FRS-mediated FGFR1 signaling; FGFR3c ligand binding and activation; FRS-mediated FGFR4 signaling; FGFR3b ligand binding and activation; PI-3K cascade:FGFR3" 0 High Q8CIV2 Membralin OS=Mus musculus OX=10090 GN=Tmem259 PE=1 SV=2 0.003 2.995 3 1 1 1 574 63.5 5.49 1 1 regulation of biological process;response to stimulus endoplasmic reticulum;membrane protein binding Pf09746 216157 ENSMUSG00000013858.14 ORF61; Tmem259 10 0 High Q91ZE0 "Trimethyllysine dioxygenase, mitochondrial OS=Mus musculus OX=10090 GN=Tmlhe PE=1 SV=2" 0.004 2.649 3 1 1 1 421 49.6 8.25 1 1 1046327.938 1527259.5 1647438.375 3282659.5 1 1 1 1 metabolic process;regulation of biological process mitochondrion;organelle lumen catalytic activity;metal ion binding "Pf02668, Pf06155" 192289 ENSMUSG00000079834.2 Tmlhe X Carnitine synthesis Lysine degradation 0 High G5E881 "Phosphatidate cytidylyltransferase, mitochondrial OS=Mus musculus OX=10090 GN=Tamm41 PE=1 SV=1" 0.004 2.647 4 1 1 1 337 37.9 9.11 1 1 Met-loss+Acetyl [N-Term] metabolic process membrane;mitochondrion catalytic activity Pf09139 68971 ENSMUSG00000030316.13 Tamm41 6 0 Low G3X9R7 RING finger protein 148 OS=Mus musculus OX=10090 GN=Rnf148 PE=2 SV=1 0.053 1.006 5 1 1 1 316 35.4 8.47 1 1 26433414 21513454 38631360 18900990 1 1 1 1 membrane metal ion binding;protein binding "Pf00097, Pf02225, Pf12678, Pf13639, Pf13920, Pf13923, Pf14634" 71300 ENSMUSG00000078179.1 Rnf148 6 0 High B1B1D8 "39S ribosomal protein L2, mitochondrial OS=Mus musculus OX=10090 GN=Mrpl2 PE=1 SV=1" 0.006 2.112 4 1 1 1 304 33.1 11.06 1 1 cell organization and biogenesis;metabolic process mitochondrion;ribosome catalytic activity;RNA binding;structural molecule activity "Pf00181, Pf03947" 27398 ENSMUSG00000002767.13 Mrpl2 17 0 High E9PWN2 Isoleucyl-tRNA synthetase OS=Mus musculus OX=10090 GN=Iars2 PE=1 SV=1 0 4.91 5 1 1 1 733 81.1 7.68 1 1 metabolic process;regulation of biological process cytoplasm;mitochondrion catalytic activity;nucleotide binding "Pf00133, Pf01921, Pf09334, Pf13603" ENSMUSG00000026618.11 1 0 Low Q3TEA8 Heterochromatin protein 1-binding protein 3 OS=Mus musculus OX=10090 GN=Hp1bp3 PE=1 SV=1 0.068 0.895 1 1 1 1 554 60.8 9.7 1 1 551952 1 cell organization and biogenesis;regulation of biological process;response to stimulus chromosome;nucleus DNA binding;protein binding Pf00538 15441 ENSMUSG00000028759.13 Hp1bp3 4 0 Medium Q9D404 "3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial OS=Mus musculus OX=10090 GN=Oxsm PE=1 SV=1" 0.025 1.261 2 1 1 1 459 48.6 7.06 1 1 metabolic process cytosol;mitochondrion catalytic activity "Pf00109, Pf02801" 71147 ENSMUSG00000021786.12 Oxsm 14 Fatty acid metabolism; Metabolic pathways; Biotin metabolism; Fatty acid biosynthesis 0 Medium A0A0R4J098 Zinc finger protein 326 OS=Mus musculus OX=10090 GN=Zfp326 PE=1 SV=1 0.03 1.151 2 1 1 1 580 65.1 5.21 1 1 443473.5938 1 metabolic process;regulation of biological process nucleus;spliceosomal complex DNA binding;metal ion binding;protein binding;RNA binding Pf04988 54367 ENSMUSG00000029290.12 Zfp326 5 0 High A0A140LIS5 Arginine and glutamate-rich protein 1 (Fragment) OS=Mus musculus OX=10090 GN=Arglu1 PE=1 SV=1 0.01 1.787 4 1 1 1 215 25.9 10.62 1 1 ENSMUSG00000040459.11 8 0 High Q9DCJ5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Mus musculus OX=10090 GN=Ndufa8 PE=1 SV=3 0 3.766 10 1 1 1 172 20 8.46 1 1 cell organization and biogenesis;metabolic process;transport membrane;mitochondrion protein binding Pf06747 68375 ENSMUSG00000026895.7 Ndufa8 2 Complex I biogenesis Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High P57784 U2 small nuclear ribonucleoprotein A' OS=Mus musculus OX=10090 GN=Snrpa1 PE=1 SV=2 0 4.324 5 1 1 1 255 28.3 8.62 1 1 metabolic process nucleus;spliceosomal complex protein binding;RNA binding "Pf12799, Pf13855, Pf14580" 68981 ENSMUSG00000030512.13 Snrpa1 7 mRNA Splicing - Major Pathway Spliceosome 0 High S4R1B3 "Serine protease HTRA2, mitochondrial OS=Mus musculus OX=10090 GN=Htra2 PE=1 SV=1" 0.007 2.052 4 1 1 1 328 34.8 9.45 1 1 450610.875 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion catalytic activity "Pf00089, Pf13365" ENSMUSG00000068329.12 6 0 High Q3UH45 Tectonin beta-propeller repeat-containing 2 OS=Mus musculus OX=10090 GN=Tecpr2 PE=1 SV=1 0 4.683 1 1 1 1 1423 154.8 5.38 1 1 574592.5625 4574020 1 1 protein binding Pf06462 104859 ENSMUSG00000021275.15 Tecpr2 12 0 Medium Q922B2 "Aspartate--tRNA ligase, cytoplasmic OS=Mus musculus OX=10090 GN=Dars1 PE=1 SV=2" 0.034 1.109 1 1 1 1 501 57.1 6.49 1 1 713611.1875 2416069 1 1 metabolic process cytoplasm;cytosol;membrane catalytic activity;nucleotide binding;RNA binding "Pf00152, Pf01336" 226414 ENSMUSG00000026356.15 Dars 1 Aminoacyl-tRNA biosynthesis 0 High A0A087WS46 Eukaryotic translation elongation factor 1 beta 2 OS=Mus musculus OX=10090 GN=Eef1b2 PE=1 SV=1 0.004 2.544 5 1 1 1 184 20.1 4.56 1 1 3738235.5 1 metabolic process RNA binding Pf00736 ENSMUSG00000025967.16 1 0 High Q9Z0M5 Lysosomal acid lipase/cholesteryl ester hydrolase OS=Mus musculus OX=10090 GN=Lipa PE=1 SV=2 0.006 2.26 3 1 1 1 397 45.3 8.07 1 1 3617770.5 1 cell organization and biogenesis;cell proliferation;defense response;metabolic process;response to stimulus vacuole catalytic activity "Pf00561, Pf04083, Pf12695, Pf12697" 16889 ENSMUSG00000024781.15 Lipa 19 LDL clearance Steroid biosynthesis; Lysosome 0 High Q6P069 Sorcin OS=Mus musculus OX=10090 GN=Sri PE=1 SV=1 0.006 2.271 6 1 1 1 198 21.6 5.59 1 1 metabolic process;regulation of biological process;transport cytoplasm;cytosol;endoplasmic reticulum;membrane;mitochondrion catalytic activity;metal ion binding;protein binding "Pf13405, Pf13499, Pf13833" 109552 ENSMUSG00000003161.15 Sri 5 Ion homeostasis; Ion transport by P-type ATPases; Stimuli-sensing channels; Sodium/Calcium exchangers; Reduction of cytosolic Ca++ levels 0 Medium P39876 Metalloproteinase inhibitor 3 OS=Mus musculus OX=10090 GN=Timp3 PE=1 SV=1 0.045 1.029 4 1 1 1 211 24.2 8.76 1 1 1051241.375 1 regulation of biological process;response to stimulus cytoplasm;extracellular;nucleus enzyme regulator activity;metal ion binding;protein binding Pf00965 21859 ENSMUSG00000020044.13 Timp3 10 Platelet degranulation MicroRNAs in cancer; Proteoglycans in cancer 0 High Q3U0S6 Ras-interacting protein 1 OS=Mus musculus OX=10090 GN=Rasip1 PE=1 SV=3 0.007 1.957 1 1 1 1 961 103.5 7.83 1 1 703656.75 1 cell differentiation;regulation of biological process;response to stimulus cytoplasm;Golgi protein binding "Pf00788, Pf01843" 69903 ENSMUSG00000044562.12 Rasip1 7 0 High A0A140T8N4 Immunoglobulin kappa variable 5-37 (Fragment) OS=Mus musculus OX=10090 GN=Igkv5-37 PE=4 SV=2 0 4.182 10 1 1 1 115 12.6 8 1 1 1448484.875 6392197.5 1 1 "Pf00047, Pf07679, Pf07686" 384417 ENSMUSG00000076571.2 Igkv5-37 6 0 Medium H7BWY5 Protein mono-ADP-ribosyltransferase PARP9 OS=Mus musculus OX=10090 GN=Parp9 PE=1 SV=1 0.027 1.163 2 1 1 1 597 66.9 6.24 1 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;enzyme regulator activity;nucleotide binding;protein binding Pf01661 80285 ENSMUSG00000022906.15 Parp9 16 0 High G3UX79 "28S ribosomal protein S18b, mitochondrial (Fragment) OS=Mus musculus OX=10090 GN=Mrps18b PE=1 SV=1" 0.003 3.087 5 1 1 1 188 21.5 7.43 1 1 2427634 2976332.75 4665132 1 1 1 metabolic process mitochondrion;ribosome structural molecule activity Pf01084 ENSMUSG00000024436.16 17 0 High O55013 Trafficking protein particle complex subunit 3 OS=Mus musculus OX=10090 GN=Trappc3 PE=1 SV=1 0.007 1.878 8 1 1 1 180 20.3 4.96 1 1 455773.875 1 transport cytosol;endoplasmic reticulum;Golgi;membrane protein binding Pf04051 27096 ENSMUSG00000028847.8 Trappc3 4 COPII (Coat Protein 2) Mediated Vesicle Transport; RAB GEFs exchange GTP for GDP on RABs 0 Medium Q9Z1J3 "Cysteine desulfurase, mitochondrial OS=Mus musculus OX=10090 GN=Nfs1 PE=1 SV=3" 0.012 1.575 3 1 1 1 459 50.5 8.16 1 1 cell organization and biogenesis;metabolic process cytoplasm;cytosol;mitochondrion;nucleus;organelle lumen catalytic activity;metal ion binding;protein binding "Pf00266, Pf00282, Pf01212" 18041 ENSMUSG00000027618.17 Nfs1 2 Mitochondrial iron-sulfur cluster biogenesis; Molybdenum cofactor biosynthesis Thiamine metabolism; Metabolic pathways; Sulfur relay system 0 High A0A0G2JDK2 Glucosylceramidase OS=Mus musculus OX=10090 GN=Gba PE=1 SV=1 0.01 1.729 2 1 1 1 388 43.3 8.75 1 1 3465530.5 1 cell communication;metabolic process;regulation of biological process;response to stimulus membrane;organelle lumen;vacuole catalytic activity;protein binding Pf02055 14466 ENSMUSG00000028048.11 Gba 3 0 High P61205 ADP-ribosylation factor 3 OS=Mus musculus OX=10090 GN=Arf3 PE=2 SV=2 0 5.276 8 1 1 1 181 20.6 7.43 1 1 regulation of biological process;response to stimulus;transport cytoplasm;Golgi catalytic activity;nucleotide binding;protein binding;signal transducer activity "Pf00025, Pf00071, Pf00503, Pf01926, Pf04670, Pf08477, Pf09439" 11842 ENSMUSG00000051853.9 Arf3 15 Synthesis of PIPs at the Golgi membrane Endocytosis 0 High Q3UJU9 Regulator of microtubule dynamics protein 3 OS=Mus musculus OX=10090 GN=Rmdn3 PE=1 SV=2 0 4.195 5 1 1 1 470 52 5.21 1 1 cell death;cell differentiation;cellular homeostasis cytoplasm;cytoskeleton;membrane;mitochondrion;nucleus protein binding 67809 ENSMUSG00000070730.11 Fam82a2; Rmdn3 2 0 High Q3UPL0 Protein transport protein Sec31A OS=Mus musculus OX=10090 GN=Sec31a PE=1 SV=2 0.003 3.216 2 1 1 1 1230 133.5 6.76 1 1 114712.3828 472487.6875 1 1 cell organization and biogenesis;response to stimulus;transport cytoplasm;cytosol;endoplasmic reticulum;endosome;membrane protein binding "Pf03154, Pf12931" 69162 ENSMUSG00000035325.16 Sec31a 5 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC; COPII (Coat Protein 2) Mediated Vesicle Transport; MHC class II antigen presentation" Protein processing in endoplasmic reticulum 0 High P03911 NADH-ubiquinone oxidoreductase chain 4 OS=Mus musculus OX=10090 GN=Mtnd4 PE=1 SV=1 0.003 3.224 4 1 1 1 459 51.8 9.38 1 1 63567.80078 348490.625 1556603.625 1 1 1 metabolic process;response to stimulus;transport membrane;mitochondrion catalytic activity "Pf00361, Pf01059" 17719; 3338899 ENSMUSG00000064363.1 ND4 MT Complex I biogenesis Metabolic pathways; Oxidative phosphorylation; Parkinson's disease 0 Medium O70479 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 OS=Mus musculus OX=10090 GN=Tnfaip1 PE=2 SV=1 0.027 1.158 2 1 1 1 316 36.1 7.84 1 1 210689.8438 2582879.75 2207019 1 1 1 cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus cytoplasm;endosome;nucleus catalytic activity;protein binding Pf02214 21927 ENSMUSG00000017615.12 Tnfaip1 11 0 High F6VY18 GMP reductase (Fragment) OS=Mus musculus OX=10090 GN=Gmpr PE=1 SV=1 0.01 1.73 3 1 1 1 290 31.2 6.46 1 1 509573.1563 1 metabolic process catalytic activity "Pf00478, Pf01645" ENSMUSG00000000253.12 13 0 High O35683 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 OS=Mus musculus OX=10090 GN=Ndufa1 PE=1 SV=1 0.004 2.658 14 1 1 1 70 8.1 9.48 1 1 cell organization and biogenesis;metabolic process;transport cytosol;membrane;mitochondrion 54405 ENSMUSG00000016427.7 Ndufa1 X Complex I biogenesis Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 Low A2AQQ8 Nuclear receptor subfamily 4 group A member 2 OS=Mus musculus OX=10090 GN=Nr4a2 PE=1 SV=1 0.078 0.807 2 1 1 1 535 59.8 8.31 1 1 cell communication;cell differentiation;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus DNA binding;metal ion binding;protein binding;receptor activity;signal transducer activity "Pf00104, Pf00105" 18227 ENSMUSG00000026826.13 Nr4a2 2 0 Low A0A0R4J2B7 Dedicator of cytokinesis protein 10 (Fragment) OS=Mus musculus OX=10090 GN=Dock10 PE=1 SV=1 0.074 0.827 1 1 1 1 1816 207.4 8.03 1 1 cell differentiation;cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus protein binding "Pf06920, Pf14429" 210293 ENSMUSG00000038608.15 Dock10 1 0 High Q91W39 Nuclear receptor coactivator 5 OS=Mus musculus OX=10090 GN=Ncoa5 PE=1 SV=1 0.003 3.282 5 1 1 1 579 65.3 9.82 1 1 1016759.625 1 metabolic process;regulation of biological process cytoskeleton;nucleus RNA binding 228869 ENSMUSG00000039804.15 Ncoa5 2 0 High O88393 Transforming growth factor beta receptor type 3 OS=Mus musculus OX=10090 GN=Tgfbr3 PE=1 SV=1 0.003 3.323 1 1 1 1 850 93.8 6 1 1 cell differentiation;cell growth;cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process;response to stimulus cell surface;cytoplasm;endoplasmic reticulum;extracellular;membrane catalytic activity;protein binding;receptor activity;signal transducer activity Pf00100 21814 Tgfbr3 5 0 Medium P41317 Mannose-binding protein C OS=Mus musculus OX=10090 GN=Mbl2 PE=1 SV=2 0.016 1.435 6 1 1 1 244 25.9 5.06 1 1 336225.25 1 defense response;metabolic process;regulation of biological process;response to stimulus extracellular metal ion binding;protein binding Pf00059 17195 ENSMUSG00000024863.5 Mbl2 19 Lectin pathway of complement activation Staphylococcus aureus infection; Phagosome; Complement and coagulation cascades 0 High A0A075B5S4 Immunoglobulin heavy variable V3-3 OS=Mus musculus OX=10090 GN=Ighv3-3 PE=4 SV=1 0 3.825 16 1 1 1 98 11.2 6.51 1 1 ENSMUSG00000094029.2 LOC671290 12 0 High Q8BGQ7 "Alanine--tRNA ligase, cytoplasmic OS=Mus musculus OX=10090 GN=Aars1 PE=1 SV=1" 0.01 1.788 1 1 1 1 968 106.8 5.67 1 1 metabolic process;regulation of biological process cytoplasm;cytosol;membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding;protein binding;RNA binding "Pf01411, Pf02272, Pf07973" 234734 ENSMUSG00000031960.14 Aars 8 Aminoacyl-tRNA biosynthesis 0 High P47757 F-actin-capping protein subunit beta OS=Mus musculus OX=10090 GN=Capzb PE=1 SV=3 0.006 2.258 4 1 1 1 277 31.3 5.74 1 1 958540.9375 1097980.375 2031588.25 1 1 1 cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton;membrane protein binding Pf01115 12345 ENSMUSG00000028745.18 Capzb 4 COPI-independent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; MHC class II antigen presentation; Factors involved in megakaryocyte development and platelet production; HSP90 chaperone cycle for steroid hormone receptors (SHR) Endocytosis 0 High S4R191 Small integral membrane protein 1 (Fragment) OS=Mus musculus OX=10090 GN=Smim1 PE=1 SV=8 0 3.894 50 1 1 1 24 2.8 4.89 1 1 1880365.875 1 Acetyl [N-Term] ENSMUSG00000078350.11 4 0 Medium Q6A078 Centrosomal protein of 290 kDa OS=Mus musculus OX=10090 GN=Cep290 PE=1 SV=2 0.016 1.4 0 1 1 1 2472 288.9 6.1 1 1 6330763.5 8372219.5 9758949 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;transport cytoplasm;cytoskeleton;cytosol;membrane;nucleus catalytic activity;metal ion binding;protein binding Pf00246 216274 ENSMUSG00000019971.10 Cep290 10 Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Regulation of PLK1 Activity at G2/M Transition; Neutrophil degranulation; Recruitment of NuMA to mitotic centrosomes 0 Medium Q91YT2 E3 ubiquitin-protein ligase RNF185 OS=Mus musculus OX=10090 GN=Rnf185 PE=2 SV=1 0.025 1.243 5 1 1 1 192 20.5 6.52 1 1 metabolic process;response to stimulus endoplasmic reticulum;membrane;mitochondrion catalytic activity;metal ion binding;protein binding "Pf00097, Pf12678, Pf12861, Pf13445, Pf13639, Pf13920, Pf13923, Pf14634, Pf15227" 193670 ENSMUSG00000020448.16 Rnf185 11 ABC-family proteins mediated transport; ER Quality Control Compartment (ERQC) Protein processing in endoplasmic reticulum 0 High Q8BGY2 Eukaryotic translation initiation factor 5A-2 OS=Mus musculus OX=10090 GN=Eif5a2 PE=1 SV=3 0.006 2.09 8 1 1 1 153 16.8 5.58 1 1 metabolic process;regulation of biological process;transport cytoplasm;endoplasmic reticulum;membrane;nucleus RNA binding Pf01287 208691 ENSMUSG00000050192.8 Eif5a2 3 Hypusine synthesis from eIF5A-lysine 0 High Q3URQ4 "Family with sequence similarity 8, member A1 OS=Mus musculus OX=10090 GN=Fam8a1 PE=1 SV=1" 0 6.064 9 1 1 1 399 42.3 6.71 1 1 5345834.5 1 membrane Pf06271 97863 ENSMUSG00000069237.8 C78339; Fam8a1 13 0 High Q921I1 Serotransferrin OS=Mus musculus OX=10090 GN=Tf PE=1 SV=1 0.003 2.751 2 1 1 1 697 76.7 7.18 1 1 340342.9063 735256.5 976728.9375 1 1 1 cell differentiation;cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cell surface;endosome;extracellular;membrane metal ion binding;protein binding;transporter activity "Pf00405, Pf12974" 22041 ENSMUSG00000032554.15 Trf 9 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Platelet degranulation ; Cargo recognition for clathrin-mediated endocytosis; Transferrin endocytosis and recycling Mineral absorption; HIF-1 signaling pathway 0 High A0A0G2JE46 HCLS1-associated protein X-1 OS=Mus musculus OX=10090 GN=Hax1 PE=1 SV=1 0.006 2.255 4 1 1 1 196 22.2 4.74 1 1 1004816.438 1 Met-loss+Acetyl [N-Term] cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;endoplasmic reticulum;membrane;mitochondrion;nucleus protein binding 23897 ENSMUSG00000027944.13 Hax1 3 0 High A0A2I3BS14 Carboxypeptidase Q (Fragment) OS=Mus musculus OX=10090 GN=Cpq PE=1 SV=1 0 4.775 7 1 1 1 198 22 9.07 1 1 0 High O09165 Calsequestrin-1 OS=Mus musculus OX=10090 GN=Casq1 PE=1 SV=3 0 4.218 4 1 1 1 405 46.3 4.12 1 1 cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;endoplasmic reticulum;Golgi;membrane;mitochondrion;organelle lumen metal ion binding;protein binding "Pf01216, Pf13848" 12372 ENSMUSG00000007122.11 Casq1 1 Stimuli-sensing channels; Ion homeostasis 0 High O08538 Angiopoietin-1 OS=Mus musculus OX=10090 GN=Angpt1 PE=1 SV=2 0.006 2.198 2 1 1 1 498 57.5 6.76 1 1 cell differentiation;cell organization and biogenesis;cellular component movement;development;metabolic process;regulation of biological process;response to stimulus extracellular;membrane protein binding "Pf00147, Pf13851" 11600 ENSMUSG00000022309.8 Angpt1 15 RAF/MAP kinase cascade; Interleukin-20 family signaling; Tie2 Signaling Ras signaling pathway; Rheumatoid arthritis; Rap1 signaling pathway; HIF-1 signaling pathway; PI3K-Akt signaling pathway 0 High Q9CQZ6 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 OS=Mus musculus OX=10090 GN=Ndufb3 PE=1 SV=1 0.001 3.583 11 1 1 1 104 11.7 9.04 1 1 cell organization and biogenesis;metabolic process;transport membrane;mitochondrion Pf08122 66495 ENSMUSG00000026032.8 Ndufb3 1 Complex I biogenesis Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High Q8BK64 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Mus musculus OX=10090 GN=Ahsa1 PE=1 SV=2 0 6.746 7 1 1 1 338 38.1 5.53 1 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;endoplasmic reticulum enzyme regulator activity;protein binding "Pf08327, Pf09229" 217737 ENSMUSG00000021037.6 Ahsa1 12 0 High P48678 Prelamin-A/C OS=Mus musculus OX=10090 GN=Lmna PE=1 SV=2 0.008 1.855 2 1 1 1 665 74.2 6.98 1 1 458015.0938 1 cell organization and biogenesis;regulation of biological process;response to stimulus;transport membrane;nucleus protein binding;structural molecule activity "Pf00038, Pf00932, Pf12128" 16905 ENSMUSG00000028063.15 Lmna 3 Clearance of Nuclear Envelope Membranes from Chromatin; Breakdown of the nuclear lamina; Depolymerisation of the Nuclear Lamina; Initiation of Nuclear Envelope Reformation Hypertrophic cardiomyopathy (HCM); Arrhythmogenic right ventricular cardiomyopathy (ARVC); Dilated cardiomyopathy; Apoptosis 0 High Q9D074 E3 ubiquitin-protein ligase MGRN1 OS=Mus musculus OX=10090 GN=Mgrn1 PE=1 SV=2 0 4.163 7 1 1 1 532 58.4 4.88 1 1 metabolic process;regulation of biological process;transport cytoplasm;endosome;membrane;nucleus catalytic activity;metal ion binding;protein binding "Pf00097, Pf13639, Pf13920, Pf13923, Pf14634" 17237 ENSMUSG00000022517.16 Mgrn1 16 Ubiquitin mediated proteolysis 0 Medium A0A0U1RPA7 Remodeling and spacing factor 1 (Fragment) OS=Mus musculus OX=10090 GN=Rsf1 PE=1 SV=1 0.043 1.04 33 1 1 1 109 11.6 5.41 1 1 223966.9063 300717.6875 1 1 cell organization and biogenesis;metabolic process;regulation of biological process nucleus protein binding ENSMUSG00000035623.14 7 Deposition of new CENPA-containing nucleosomes at the centromere 0 High A0A1W2P6N8 Collagen alpha-1(XVIII) chain (Fragment) OS=Mus musculus OX=10090 GN=Col18a1 PE=1 SV=1 0.007 1.967 4 1 1 1 225 23.6 9.64 1 1 374044.1563 1 structural molecule activity Pf06482 ENSMUSG00000001435.15 10 0 High G3X9T7 Galectin-9 OS=Mus musculus OX=10090 GN=Lgals9 PE=1 SV=1 0.003 2.948 4 1 1 1 353 40 9.31 1 1 regulation of biological process;response to stimulus cytoplasm;cytosol;extracellular;nucleus enzyme regulator activity;protein binding Pf00337 16859 ENSMUSG00000001123.15 Lgals9 11 0 Low P56404 Aquaporin-8 OS=Mus musculus OX=10090 GN=Aqp8 PE=2 SV=1 0.073 0.864 3 1 1 1 261 27.8 5.86 1 1 response to stimulus;transport membrane transporter activity Pf00230 11833 ENSMUSG00000030762.11 Aqp8 7 Passive transport by Aquaporins Bile secretion 0 High Q8K3J1 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial OS=Mus musculus OX=10090 GN=Ndufs8 PE=1 SV=1" 0.008 1.863 5 1 1 1 212 24 6.21 1 1 715485 2328528 1 1 cell organization and biogenesis;metabolic process;response to stimulus;transport membrane;mitochondrion catalytic activity;metal ion binding "Pf00037, Pf12797, Pf12837, Pf12838, Pf13183, Pf13187, Pf13237, Pf13459, Pf13484, Pf13534, Pf14697" 225887 ENSMUSG00000059734.6 Ndufs8 19 Complex I biogenesis Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High Q91Z38 Tetratricopeptide repeat protein 1 OS=Mus musculus OX=10090 GN=Ttc1 PE=1 SV=1 0.006 2.306 3 1 1 1 292 33.2 5.01 1 1 cytosol;membrane protein binding "Pf00515, Pf13371, Pf13414, Pf13432" 66827 ENSMUSG00000041278.10 Ttc1 11 0 High E9PW20 Chromatin target of PRMT1 protein OS=Mus musculus OX=10090 GN=Chtop PE=1 SV=1 0 4.074 6 1 1 1 203 22.1 11.97 1 1 metabolic process;regulation of biological process nucleus protein binding;RNA binding Pf13865 66511 ENSMUSG00000001017.15 Chtop 3 0 Medium Q62377 U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 OS=Mus musculus OX=10090 GN=Zrsr2 PE=1 SV=1 0.015 1.504 2 1 1 1 462 55.3 8.43 1 1 14451850 23995958 24344166 13257294 1 1 1 1 cell organization and biogenesis;metabolic process nucleus;spliceosomal complex metal ion binding;RNA binding "Pf00076, Pf00642, Pf13893, Pf14259" 22184 Zrsr2 X 0 High P58158 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 OS=Mus musculus OX=10090 GN=B3gat3 PE=1 SV=1 0.003 2.863 3 1 1 1 335 37 8.78 1 1 metabolic process;regulation of biological process Golgi;membrane catalytic activity;enzyme regulator activity;metal ion binding Pf03360 72727 ENSMUSG00000071649.5 B3gat3 19 A tetrasaccharide linker sequence is required for GAG synthesis Metabolic pathways; Glycosaminoglycan biosynthesis - heparan sulfate / heparin; Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate 0 Medium Q8BGS1 Band 4.1-like protein 5 OS=Mus musculus OX=10090 GN=Epb41l5 PE=1 SV=1 0.017 1.368 4 1 1 1 731 81.6 6.39 1 1 242118.8281 442516.0625 1 1 cell growth;cell organization and biogenesis;cellular component movement;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;membrane protein binding;structural molecule activity "Pf00373, Pf08736, Pf09379, Pf09380" 226352 ENSMUSG00000026383.14 Epb4.1l5; Epb41l5 1 Neurexins and neuroligins 0 High Q9D0I9 "Arginine--tRNA ligase, cytoplasmic OS=Mus musculus OX=10090 GN=Rars1 PE=1 SV=2" 0.003 2.726 2 1 1 1 660 75.6 7.55 1 1 790414.5625 20771824 1 1 metabolic process cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00750, Pf03485, Pf05746" 104458 ENSMUSG00000018848.4 Rars 11 Aminoacyl-tRNA biosynthesis 0 High Q9CQZ5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Mus musculus OX=10090 GN=Ndufa6 PE=1 SV=1 0.001 3.46 13 1 1 1 131 15.3 10.11 1 1 582624.1875 1 metabolic process;response to stimulus;transport membrane;mitochondrion "Pf05347, Pf13232, Pf13233" 67130 ENSMUSG00000022450.5 Ndufa6 15 Complex I biogenesis Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 Medium A2BGI9 Peptidyl-prolyl cis-trans isomerase OS=Mus musculus OX=10090 GN=Ppih PE=1 SV=1 0.011 1.651 7 1 1 1 134 14.5 7.99 1 1 481485.4688 2935611.25 1539288 1 1 1 metabolic process;regulation of biological process cytoplasm catalytic activity Pf00160 66101 ENSMUSG00000033036.9; ENSMUSG00000060288.13 Ppih 4; 5 0 High Q8C1Q6 Small integral membrane protein 4 OS=Mus musculus OX=10090 GN=Smim4 PE=1 SV=2 0.006 2.13 15 1 1 1 80 9.7 10.93 1 1 2895263 2747729.25 3671639.75 3256779.25 1 1 1 1 membrane;mitochondrion Pf15114 66487 ENSMUSG00000058351.10 2010107H07Rik; Smim4 14 0 High Q8CG76 Aflatoxin B1 aldehyde reductase member 2 OS=Mus musculus OX=10090 GN=Akr7a2 PE=1 SV=3 0.003 3.264 3 1 1 1 367 40.6 8.12 1 1 metabolic process cytoplasm;cytosol;Golgi;mitochondrion catalytic activity Pf00248 110198 ENSMUSG00000028743.7 Akr7a5 4 Aflatoxin activation and detoxification Metabolism of xenobiotics by cytochrome P450 0 High A0A1L1SRL0 SAFB-like transcription modulator OS=Mus musculus OX=10090 GN=Sltm PE=1 SV=1 0 6.006 34 1 1 1 62 6.6 10.73 1 1 Met-loss+Acetyl [N-Term] Pf02037 ENSMUSG00000032212.10 9 0 Low Q3URV1 Protein broad-minded OS=Mus musculus OX=10090 GN=Tbc1d32 PE=1 SV=2 0.053 1.001 1 1 1 1 1296 148 6.15 1 1 650259.625 1 cell organization and biogenesis;development;regulation of biological process;response to stimulus cytoplasm protein binding Pf14961 544696 ENSMUSG00000038122.9 D630037F22Rik; Tbc1d32 10 0 High H3BJI5 Peptidylprolyl isomerase OS=Mus musculus OX=10090 GN=Fkbp7 PE=1 SV=1 0 4.643 12 1 1 1 123 13.8 6.89 1 1 7775936.5 1 metabolic process endoplasmic reticulum catalytic activity;metal ion binding Pf00254 ENSMUSG00000002732.14 2 0 High Q9D1I6 "39S ribosomal protein L14, mitochondrial OS=Mus musculus OX=10090 GN=Mrpl14 PE=1 SV=1" 0 4.23 7 1 1 1 145 15.9 10.99 1 1 487899.3438 1 metabolic process mitochondrion;ribosome RNA binding;structural molecule activity Pf00238 68463 ENSMUSG00000023939.7 Mrpl14 17 Mitochondrial translation termination; Mitochondrial translation elongation Ribosome 0 High Q04750 DNA topoisomerase 1 OS=Mus musculus OX=10090 GN=Top1 PE=1 SV=2 0.004 2.579 1 1 1 1 767 90.8 9.33 1 1 cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus chromosome;cytoplasm;nucleus catalytic activity;DNA binding;nucleotide binding;protein binding;RNA binding "Pf01028, Pf02919, Pf14370" 21969 ENSMUSG00000070544.6 Top1 2 SUMOylation of DNA replication proteins 0 Medium Q7TNS2 MICOS complex subunit Mic10 OS=Mus musculus OX=10090 GN=Micos10 PE=1 SV=1 0.013 1.536 11 1 1 1 76 8.6 8.94 1 1 8374885 1 Met-loss+Acetyl [N-Term] membrane;mitochondrion Pf04418 433771 ENSMUSG00000050608.11 Minos1 4 0 Medium I7HJS2 Tafazzin family protein OS=Mus musculus OX=10090 GN=Taz PE=1 SV=1 0.015 1.522 5 1 1 1 263 30.4 8.95 1 1 cell organization and biogenesis;metabolic process;regulation of biological process cytoplasm;cytosol;membrane;mitochondrion;nucleus catalytic activity Pf01553 66826 ENSMUSG00000009995.17 Taz X Acyl chain remodeling of CL Glycerophospholipid metabolism 0 High Q80ZS7 Dynein light chain OS=Mus musculus OX=10090 GN=BC048507 PE=1 SV=1 0.003 2.91 12 1 1 1 89 10.4 8.27 1 1 1904718.5 3528289 1 1 cell organization and biogenesis;cellular component movement;regulation of biological process;transport catalytic activity;motor activity;protein binding Pf01221 408058 ENSMUSG00000064063.5 BC048507 13 0 Medium P02463 Collagen alpha-1(IV) chain OS=Mus musculus OX=10090 GN=Col4a1 PE=1 SV=4 0.01 1.673 1 1 1 1 1669 160.6 8.24 1 1 1620738.25 1990598.875 1 1 cell differentiation;cell organization and biogenesis;regulation of biological process;response to stimulus extracellular protein binding;structural molecule activity "Pf01391, Pf01413" 12826 ENSMUSG00000031502.11 Col4a1 8 Anchoring fibril formation; Laminin interactions; Crosslinking of collagen fibrils; Collagen chain trimerization; Integrin cell surface interactions; NCAM1 interactions; Collagen degradation; Non-integrin membrane-ECM interactions; Signaling by PDGF AGE-RAGE signaling pathway in diabetic complications; Focal adhesion; Protein digestion and absorption; Small cell lung cancer; Pathways in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway; Amoebiasis 0 Medium Q9DBE8 "Alpha-1,3/1,6-mannosyltransferase ALG2 OS=Mus musculus OX=10090 GN=Alg2 PE=1 SV=2" 0.025 1.262 1 1 1 1 415 47.4 7.97 1 1 3934458.75 1 metabolic process;response to stimulus cytoplasm;membrane;nucleus catalytic activity;protein binding "Pf00534, Pf13439, Pf13524, Pf13579, Pf13692" 56737 ENSMUSG00000039740.6 Alg2 4 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" Metabolic pathways; N-Glycan biosynthesis 0 High Q505D7 Optic atrophy 3 protein homolog OS=Mus musculus OX=10090 GN=Opa3 PE=1 SV=1 0 3.837 7 1 1 1 179 20.1 8.34 1 1 cell organization and biogenesis;regulation of biological process mitochondrion Pf07047 403187 ENSMUSG00000052214.9 Opa3 7 0 Medium Q8R2P8 Lysine--tRNA ligase OS=Mus musculus OX=10090 GN=Kars PE=1 SV=1 0.041 1.052 2 1 1 1 624 71.2 6.43 1 1 451827.8125 1 metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;extracellular;membrane;mitochondrion;nucleus catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00152, Pf00587, Pf01336" 85305 ENSMUSG00000031948.14 Kars 8 0 Medium Q5SRX1 TOM1-like protein 2 OS=Mus musculus OX=10090 GN=Tom1l2 PE=1 SV=1 0.01 1.673 4 1 1 1 507 55.6 4.82 1 1 Acetyl [N-Term] regulation of biological process;response to stimulus;transport protein binding "Pf00790, Pf01417, Pf03127" 216810 ENSMUSG00000000538.18 Tom1l2 11 0 High A0A0A6YXK7 Centrosomal protein of 170 kDa (Fragment) OS=Mus musculus OX=10090 GN=Cep170 PE=1 SV=1 0.01 1.74 1 1 1 1 787 85.9 8.63 1 1 Pf15308 ENSMUSG00000057335.11 1 0 High Q9Z2M7 Phosphomannomutase 2 OS=Mus musculus OX=10090 GN=Pmm2 PE=1 SV=1 0.001 3.551 7 1 1 1 242 27.6 6.42 1 1 143286.5625 213499.1719 1 1 Met-loss+Acetyl [N-Term] metabolic process;transport cytoplasm;cytosol;nucleus catalytic activity "Pf03332, Pf08282" 54128 ENSMUSG00000022711.15 Pmm2 16 Synthesis of GDP-mannose Metabolic pathways; Amino sugar and nucleotide sugar metabolism; Fructose and mannose metabolism 0 High A0A498WGK2 Asparagine--tRNA ligase OS=Mus musculus OX=10090 GN=Nars PE=1 SV=1 0.006 2.184 3 1 1 1 558 64.2 5.86 1 1 0 High E9PZG9 Small nuclear ribonucleoprotein E (Fragment) OS=Mus musculus OX=10090 GN=Snrpe PE=1 SV=1 0 4.878 100 1 1 1 25 2.9 4.44 1 1 Pf01423 ENSMUSG00000090553.8 1 0 High Q05DV2 Dihydroxyacetone phosphate acyltransferase (Fragment) OS=Mus musculus OX=10090 GN=Gnpat PE=1 SV=1 0.001 3.55 2 1 1 1 585 66.6 7.18 1 1 1325730.5 1 cell organization and biogenesis;metabolic process membrane;mitochondrion;organelle lumen catalytic activity;protein binding Pf01553 14712 ENSMUSG00000031985.9 Gnpat 8 0 High Q8BXQ2 GPI transamidase component PIG-T OS=Mus musculus OX=10090 GN=Pigt PE=1 SV=2 0.01 1.783 1 1 1 1 582 65.7 8.4 1 1 cell death;cell differentiation;metabolic process cytoplasm;endoplasmic reticulum;membrane catalytic activity Pf04113 78928 ENSMUSG00000017721.15 Pigt 2 Attachment of GPI anchor to uPAR Glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Metabolic pathways 0 Medium O88696 "ATP-dependent Clp protease proteolytic subunit, mitochondrial OS=Mus musculus OX=10090 GN=Clpp PE=1 SV=1" 0.025 1.228 3 1 1 1 272 29.8 7.47 1 1 1063142.375 1 cell organization and biogenesis;metabolic process mitochondrion;organelle lumen catalytic activity;protein binding Pf00574 53895 ENSMUSG00000002660.7 Clpp 17 0 High A2AR02 Peptidyl-prolyl cis-trans isomerase G OS=Mus musculus OX=10090 GN=Ppig PE=1 SV=1 0.007 2.026 1 1 1 1 752 88.3 10.27 1 1 8639.700195 26117.24609 112731.8359 1 1 1 metabolic process cytosol;nucleus catalytic activity;RNA binding Pf00160 228005 ENSMUSG00000042133.16 Ppig 2 0 High D4AFX7 DnaJ heat shock protein family (Hsp40) member C13 OS=Mus musculus OX=10090 GN=Dnajc13 PE=1 SV=1 0.003 2.741 1 1 1 1 2248 254.9 6.77 1 1 cell differentiation;cell organization and biogenesis;regulation of biological process;transport cytosol;membrane "Pf00226, Pf14237" 235567 ENSMUSG00000032560.14 Dnajc13 9 Neutrophil degranulation 0 High P59017 Bcl-2-like protein 13 OS=Mus musculus OX=10090 GN=Bcl2l13 PE=1 SV=2 0.006 2.101 3 1 1 1 434 46.7 4.59 1 1 cell death;regulation of biological process membrane;mitochondrion Pf00452 94044 ENSMUSG00000009112.4 Bcl2l13 6 Legionellosis 0 High A0A140LHQ9 Synemin OS=Mus musculus OX=10090 GN=Synm PE=1 SV=1 0 4.36 4 1 1 1 817 90 5.05 1 1 cell organization and biogenesis cytoskeleton;membrane protein binding;structural molecule activity ENSMUSG00000030554.16 7 0 High Q8VEA4 Mitochondrial intermembrane space import and assembly protein 40 OS=Mus musculus OX=10090 GN=Chchd4 PE=1 SV=1 0.003 3.076 17 1 1 1 139 15.5 4.32 1 1 1034865.188 10045874 1 1 metabolic process;regulation of biological process;response to stimulus;transport mitochondrion catalytic activity;protein binding Pf06747 72170 ENSMUSG00000034203.8 Chchd4 6 0 Medium Q9JHI5 "Isovaleryl-CoA dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Ivd PE=1 SV=1" 0.026 1.215 2 1 1 1 424 46.3 8.29 1 1 703404.625 1668798.875 1 1 metabolic process membrane;mitochondrion;organelle lumen catalytic activity;nucleotide binding "Pf00441, Pf02770, Pf02771, Pf08028" 56357 ENSMUSG00000027332.11 Ivd 2 Branched-chain amino acid catabolism "Valine, leucine and isoleucine degradation; Metabolic pathways" 0 Medium D3Z4W5 RIKEN cDNA 1700074P13 gene (Fragment) OS=Mus musculus OX=10090 GN=1700074P13Rik PE=4 SV=1 0.023 1.281 4 1 1 1 176 20.1 5.06 1 1 527332.0625 1 metabolic process Golgi catalytic activity Pf00089 ENSMUSG00000029883.12 6 0 High Q9WTS2 "Alpha-(1,6)-fucosyltransferase OS=Mus musculus OX=10090 GN=Fut8 PE=1 SV=2" 0.007 2.014 1 1 1 1 575 66.5 7.52 1 1 3057763.25 1 cellular component movement;metabolic process;regulation of biological process;response to stimulus cytosol;Golgi;membrane catalytic activity;protein binding "Pf00018, Pf02050, Pf14604" 53618 ENSMUSG00000021065.16 Fut8 12 Reactions specific to the complex N-glycan synthesis pathway Metabolic pathways; N-Glycan biosynthesis; Transcriptional misregulation in cancer; Glycosaminoglycan biosynthesis - keratan sulfate 0 High F6RJV6 LanC-like protein 2 (Fragment) OS=Mus musculus OX=10090 GN=Lancl2 PE=1 SV=1 0 5.349 4 1 1 1 441 49.7 7.14 1 1 Pf05147 ENSMUSG00000062190.12 6 0 Medium Q91Z40 Gbp6 protein OS=Mus musculus OX=10090 GN=Gbp7 PE=1 SV=2 0.039 1.064 1 1 1 1 638 72.7 6.33 1 1 4115930.5 4780470.5 3089459.5 4549230.5 1 1 1 1 defense response;response to stimulus catalytic activity;nucleotide binding "Pf02263, Pf02841, Pf05879" 229900 ENSMUSG00000040253.15 Gbp7 3 NOD-like receptor signaling pathway 0 High P43276 Histone H1.5 OS=Mus musculus OX=10090 GN=H1-5 PE=1 SV=2 0.007 1.955 5 1 1 1 223 22.6 10.92 1 1 1245603.875 1 cell organization and biogenesis chromosome;nucleus DNA binding;protein binding Pf00538 56702 ENSMUSG00000058773.2 Hist1h1b 13 0 Low Q8CDI6 Coiled-coil domain-containing protein 158 OS=Mus musculus OX=10090 GN=Ccdc158 PE=2 SV=1 0.08 0.784 2 1 1 1 1109 126.7 6.4 1 1 cell organization and biogenesis;metabolic process;regulation of biological process catalytic activity;motor activity;structural molecule activity "Pf00038, Pf01576, Pf02463, Pf04111, Pf05483, Pf05557, Pf05622, Pf07888, Pf12128, Pf12252, Pf13166" 320696 ENSMUSG00000050050.17 Ccdc158 5 0 Low A0A0R4J1T2 RING-type E3 ubiquitin transferase (Fragment) OS=Mus musculus OX=10090 GN=Ttc3 PE=1 SV=1 0.074 0.842 1 1 1 1 776 88.8 7.68 1 1 metabolic process;regulation of biological process cytosol;membrane;nucleus;vacuole catalytic activity;metal ion binding;protein binding "Pf00515, Pf13424, Pf13432" 22129 ENSMUSG00000040785.18 Ttc3 16 0 High P61924 Coatomer subunit zeta-1 OS=Mus musculus OX=10090 GN=Copz1 PE=1 SV=1 0.001 3.448 8 1 1 1 177 20.2 4.81 1 1 420637.2813 1 Acetyl [N-Term] transport cytoplasm;Golgi;membrane Pf01217 56447 ENSMUSG00000060992.8 Copz1 15 COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic 0 High A0A075B5P1 Immunoglobulin kappa variable 3-1 (Fragment) OS=Mus musculus OX=10090 GN=Igkv3-1 PE=1 SV=7 0 3.706 13 1 1 1 119 13 4.83 1 1 1874063.25 1 response to stimulus "Pf07679, Pf07686" ENSMUSG00000095682.1 6 0 Medium G3X972 "Sec24-related gene family, member C (S. cerevisiae) OS=Mus musculus OX=10090 GN=Sec24c PE=1 SV=1" 0.027 1.181 2 1 1 1 1096 118.5 6.84 1 1 cell organization and biogenesis;transport cytoplasm;cytosol;membrane metal ion binding;protein binding "Pf00626, Pf04810, Pf04811, Pf04815, Pf08033, Pf09770" 218811 ENSMUSG00000039367.9 Sec24c 14 "Cargo concentration in the ER; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; COPII (Coat Protein 2) Mediated Vesicle Transport; MHC class II antigen presentation" 0 Medium Q8BME9 Cerebellin-4 OS=Mus musculus OX=10090 GN=Cbln4 PE=1 SV=1 0.011 1.624 4 1 1 1 198 21.6 8.73 1 1 2588797.5 10356881 9291881 12650234 1 1 1 1 transport extracellular protein binding Pf00386 228942 ENSMUSG00000067578.3 Cbln4 2 0 High O08547 Vesicle-trafficking protein SEC22b OS=Mus musculus OX=10090 GN=Sec22b PE=1 SV=3 0.009 1.832 4 1 1 1 215 24.7 8.51 1 1 Met-loss [N-Term] cell organization and biogenesis;regulation of biological process;transport endoplasmic reticulum;Golgi;membrane protein binding "Pf00957, Pf13774" 20333 ENSMUSG00000027879.9 Sec22b 3 Cargo concentration in the ER; ER-Phagosome pathway; COPI-dependent Golgi-to-ER retrograde traffic; COPII (Coat Protein 2) Mediated Vesicle Transport Phagosome; SNARE interactions in vesicular transport; Legionellosis 0 Medium A0A0G2JEW0 Death domain-containing membrane protein NRADD (Fragment) OS=Mus musculus OX=10090 GN=Nradd PE=1 SV=1 0.03 1.15 12 1 1 1 59 6.7 9.88 1 1 2876993.5 3140579 3850810.25 1 1 1 membrane;nucleus ENSMUSG00000032491.14 9 0 Low A0A5F8MQ13 Transmembrane protein 178B OS=Mus musculus OX=10090 GN=Tmem178b PE=1 SV=1 0.079 0.796 3 1 1 1 294 33.3 9.17 1 1 7525523 5482553 4861169.5 1 1 1 0 High O35963 Ras-related protein Rab-33B OS=Mus musculus OX=10090 GN=Rab33b PE=1 SV=1 0.007 1.876 5 1 1 1 229 25.8 7.69 1 1 925377.5625 1992731.75 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport Golgi;membrane;organelle lumen catalytic activity;nucleotide binding;protein binding;signal transducer activity "Pf00025, Pf00071, Pf00503, Pf01926, Pf04670, Pf08477" 19338 ENSMUSG00000027739.9 Rab33b 3 Intra-Golgi traffic 0 High E9PVM9 Lysosomal thioesterase PPT2 (Fragment) OS=Mus musculus OX=10090 GN=Ppt2 PE=1 SV=1 0.006 2.105 9 1 1 1 102 11.5 7.59 1 1 metabolic process catalytic activity ENSMUSG00000015474.16 17 0 High Q9CQN1 "Heat shock protein 75 kDa, mitochondrial OS=Mus musculus OX=10090 GN=Trap1 PE=1 SV=1" 0 3.724 2 1 1 1 706 80.2 6.68 1 1 metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion;organelle lumen nucleotide binding;protein binding;RNA binding "Pf00183, Pf02518, Pf13589" 68015 ENSMUSG00000005981.11 Trap1 16 0 High Q91VD1 Galectin-12 OS=Mus musculus OX=10090 GN=Lgals12 PE=1 SV=2 0.009 1.821 4 1 1 1 314 35.4 8.6 1 1 412428.2813 1 cell death;regulation of biological process;response to stimulus mitochondrion;nucleus Pf00337 56072 ENSMUSG00000024972.16 Lgals12 19 0 High A0A0G2JFN9 Immunoglobulin heavy variable V1-67 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-67 PE=4 SV=1 0 4.832 11 1 1 1 117 12.9 8.27 1 1 1310423 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding ENSMUSG00000095863.2 LOC641089 12 0 High A0A2R8VHR3 Mannan-binding lectin serine protease 1 OS=Mus musculus OX=10090 GN=Masp1 PE=1 SV=1 0.004 2.485 3 1 1 1 385 44.1 4.68 1 1 654092.3125 1 0 High Q3UYI1 P2X purinoceptor OS=Mus musculus OX=10090 GN=P2rx5 PE=2 SV=1 0 4.27 3 1 1 1 455 51.3 7.93 1 1 4936449.5 1 cell organization and biogenesis;regulation of biological process;response to stimulus;transport cytosol;membrane metal ion binding;nucleotide binding;receptor activity;signal transducer activity;transporter activity Pf00864 94045 ENSMUSG00000005950.14 P2rx5 11 Elevation of cytosolic Ca2+ levels Calcium signaling pathway; Neuroactive ligand-receptor interaction 0 Medium Q921G7 "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial OS=Mus musculus OX=10090 GN=Etfdh PE=1 SV=1" 0.016 1.435 2 1 1 1 616 68 7.58 1 1 598881.1875 1938001.125 1 1 metabolic process;response to stimulus;transport membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding "Pf00890, Pf01266, Pf01494, Pf01946, Pf03486, Pf05187, Pf05834, Pf07992, Pf12831, Pf13450, Pf13454, Pf13738" 66841 ENSMUSG00000027809.14 Etfdh 3 Respiratory electron transport 0 High Q99JI6 Ras-related protein Rap-1b OS=Mus musculus OX=10090 GN=Rap1b PE=1 SV=2 0.004 2.568 6 1 1 1 184 20.8 5.78 1 1 cell proliferation;regulation of biological process;response to stimulus cytoplasm;cytosol;membrane catalytic activity;nucleotide binding;protein binding "Pf00009, Pf00071, Pf08477" 215449 ENSMUSG00000052681.8 Rap1b 10 p130Cas linkage to MAPK signaling for integrins; GRB2:SOS provides linkage to MAPK signaling for Integrins ; Neutrophil degranulation; MET activates RAP1 and RAC1; Rap1 signalling Leukocyte transendothelial migration; MAPK signaling pathway; Pancreatic secretion; Ras signaling pathway; Focal adhesion; Long-term potentiation; Chemokine signaling pathway; Platelet activation; Neurotrophin signaling pathway; Rap1 signaling pathway; cAMP signaling pathway; Renal cell carcinoma 0 Medium Q91WD1 DNA-directed RNA polymerase III subunit RPC4 OS=Mus musculus OX=10090 GN=Polr3d PE=2 SV=2 0.031 1.123 5 1 1 1 398 44.3 6.98 1 1 27787960 20138812 15233840 15901298 1 1 1 1 defense response;metabolic process;regulation of biological process;response to stimulus cytosol;nucleus catalytic activity;DNA binding Pf05132 67065 ENSMUSG00000000776.12 Polr3d 14 RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA polymerase; Epstein-Barr virus infection; Metabolic pathways; Purine metabolism; Pyrimidine metabolism; Cytosolic DNA-sensing pathway 0 High A0A1L1SRX5 Peptidyl-prolyl cis-trans isomerase A OS=Mus musculus OX=10090 GN=Ppia PE=1 SV=1 0.003 2.698 48 1 1 1 40 4.6 4.73 1 1 Met-loss+Acetyl [N-Term] ENSMUSG00000071866.12 11 0 High Q9WV54 Acid ceramidase OS=Mus musculus OX=10090 GN=Asah1 PE=1 SV=1 0 4.121 3 1 1 1 394 44.6 8.46 1 1 metabolic process;response to stimulus vacuole catalytic activity "Pf02275, Pf15508" 11886 ENSMUSG00000031591.14 Asah1 8 Neutrophil degranulation; Glycosphingolipid metabolism Metabolic pathways; Lysosome; Sphingolipid signaling pathway; Sphingolipid metabolism 0 High Q8K3H0 DCC-interacting protein 13-alpha OS=Mus musculus OX=10090 GN=Appl1 PE=1 SV=1 0.003 2.794 5 1 1 1 707 79.3 5.41 1 1 cell proliferation;regulation of biological process;response to stimulus cytosol;endosome;membrane;nucleus protein binding "Pf00169, Pf00640" 72993 ENSMUSG00000040760.10 Appl1 14 Ligand-independent caspase activation via DCC Longevity regulating pathway; Pathways in cancer; Colorectal cancer 0 Medium Q8R010 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 OS=Mus musculus OX=10090 GN=Aimp2 PE=1 SV=2 0.013 1.595 8 1 1 1 320 35.4 7.83 1 1 1010184.375 1 cell death;cell differentiation;cell organization and biogenesis;development;metabolic process;regulation of biological process cytoplasm;cytosol;membrane;nucleus protein binding;structural molecule activity "Pf00043, Pf13410, Pf14497" 231872 ENSMUSG00000029610.13 Aimp2 5 0 High Q91XD7 Protein disulfide isomerase Creld1 OS=Mus musculus OX=10090 GN=Creld1 PE=1 SV=1 0.004 2.508 3 1 1 1 420 45.7 5.02 1 1 membrane metal ion binding "Pf07645, Pf11938" 171508 ENSMUSG00000030284.11 Creld1 6 0 High Q8R084 UDP-glucuronosyltransferase OS=Mus musculus OX=10090 GN=Ugt2b1 PE=1 SV=1 0.001 3.429 2 1 1 1 529 60.1 8.37 1 1 11602977 1 metabolic process;response to stimulus membrane catalytic activity "Pf00201, Pf04101" 71773 ENSMUSG00000035836.2 Ugt2b1 5 Steroid hormone biosynthesis; Drug metabolism - cytochrome P450; Retinol metabolism; Metabolic pathways; Drug metabolism - other enzymes; Ascorbate and aldarate metabolism; Chemical carcinogenesis; Porphyrin and chlorophyll metabolism; Pentose and glucuronate interconversions; Metabolism of xenobiotics by cytochrome P450 0 High Q9Z0K8 Pantetheinase OS=Mus musculus OX=10090 GN=Vnn1 PE=1 SV=3 0.001 3.365 6 1 1 1 512 57.1 5.94 1 1 defense response;metabolic process;regulation of biological process;response to stimulus membrane catalytic activity Pf00795 22361 ENSMUSG00000037440.8 Vnn1 10 Post-translational modification: synthesis of GPI-anchored proteins; Neutrophil degranulation; Vitamin B5 (pantothenate) metabolism Pantothenate and CoA biosynthesis 0 High Q920A5 Retinoid-inducible serine carboxypeptidase OS=Mus musculus OX=10090 GN=Scpep1 PE=1 SV=2 0 4.199 3 1 1 1 452 50.9 5.66 1 1 53836.98047 1140961.125 990421.625 1 1 1 metabolic process cytosol;extracellular catalytic activity Pf00450 74617 ENSMUSG00000000278.10 Scpep1 11 0 High A0A0G2JEI7 Immunoglobulin kappa chain variable 12-38 (Fragment) OS=Mus musculus OX=10090 GN=Igkv12-38 PE=4 SV=4 0 3.8 11 1 1 1 115 12.5 4.72 1 1 1278357.125 1 response to stimulus "Pf00047, Pf07679, Pf07686" 620050 ENSMUSG00000076570.6 Igkv12-38 6 0 High A0A0B4J1E2 SNW domain-containing protein 1 OS=Mus musculus OX=10090 GN=Snw1 PE=1 SV=1 0 4.333 4 1 1 1 536 61.4 9.48 1 1 150131.0625 434299.3125 785326.25 1 1 1 Met-loss+Acetyl [N-Term] cell differentiation;cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process;response to stimulus chromosome;cytoplasm;nucleus;spliceosomal complex protein binding;RNA binding Pf02731 66354 ENSMUSG00000021039.8 Snw1 12 NOTCH1 Intracellular Domain Regulates Transcription; mRNA Splicing - Major Pathway; RUNX3 regulates NOTCH signaling; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Notch-HLH transcription pathway Epstein-Barr virus infection; Spliceosome; Notch signaling pathway; Viral carcinogenesis 0 High Q9WUU7 Cathepsin Z OS=Mus musculus OX=10090 GN=Ctsz PE=1 SV=1 0.006 2.15 3 1 1 1 306 34 6.6 1 1 metabolic process;regulation of biological process cell surface;endoplasmic reticulum;vacuole catalytic activity Pf00112 64138 ENSMUSG00000016256.10 Ctsz 2 Metabolism of Angiotensinogen to Angiotensins; Lysosome Vesicle Biogenesis; Cargo concentration in the ER; COPII (Coat Protein 2) Mediated Vesicle Transport; Neutrophil degranulation Lysosome; Apoptosis 0 Medium Q9ERR7 Selenoprotein F OS=Mus musculus OX=10090 GN=Selenof PE=1 SV=3 0.038 1.07 18 1 1 1 162 17.8 5.35 1 1 83413.60156 2498887.25 1 1 cell organization and biogenesis;metabolic process endoplasmic reticulum;organelle lumen antioxidant activity;catalytic activity;protein binding Pf08806 93684 Sep15; Selenof 3 0 Medium Q8VDM6 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Mus musculus OX=10090 GN=Hnrnpul1 PE=1 SV=1 0.012 1.579 1 1 1 1 859 95.9 6.58 1 1 782042.375 1 metabolic process;regulation of biological process;response to stimulus nucleus protein binding;RNA binding "Pf00622, Pf02037, Pf13671" 232989 ENSMUSG00000040725.13 Hnrnpul1 7 mRNA Splicing - Major Pathway Influenza A 0 Medium Q9JHJ0 Tropomodulin-3 OS=Mus musculus OX=10090 GN=Tmod3 PE=1 SV=1 0.015 1.525 3 1 1 1 352 39.5 5.14 1 1 459118.9375 1 cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton protein binding Pf03250 50875 ENSMUSG00000058587.8 Tmod3 9 0 High Q6PD26 GPI transamidase component PIG-S OS=Mus musculus OX=10090 GN=Pigs PE=1 SV=3 0.001 3.604 4 1 1 1 555 61.7 6.93 1 1 metabolic process endoplasmic reticulum;membrane catalytic activity Pf10510 276846 ENSMUSG00000041958.10 Pigs 11 Attachment of GPI anchor to uPAR Glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Metabolic pathways 0 Medium A2AQN4 Propionate--CoA ligase OS=Mus musculus OX=10090 GN=Acss2 PE=1 SV=1 0.023 1.289 2 1 1 1 714 80.3 6.95 1 1 444764.0625 1 metabolic process cytoplasm;cytosol;membrane catalytic activity;nucleotide binding "Pf00501, Pf13193" 60525 ENSMUSG00000027605.18 Acss2 2 0 High P55065 Phospholipid transfer protein OS=Mus musculus OX=10090 GN=Pltp PE=1 SV=1 0.003 2.774 2 1 1 1 493 54.4 6.62 1 1 8210043.5 1 cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;transport extracellular transporter activity "Pf01273, Pf02886" 18830 ENSMUSG00000017754.13 Pltp 2 HDL remodeling PPAR signaling pathway 0 High B1ARW4 Complex I-15 kDa (Fragment) OS=Mus musculus OX=10090 GN=Ndufs5 PE=1 SV=1 0.009 1.801 9 1 1 1 91 10.9 8.94 1 1 686622.125 2501631.75 1 1 Met-loss [N-Term] cell organization and biogenesis;metabolic process;transport membrane;mitochondrion "Pf08583, Pf10200" 595136 ENSMUSG00000028648.13 Ndufs5 4 0 High Q91XE4 N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) OS=Mus musculus OX=10090 GN=Acy3 PE=1 SV=1 0.007 1.988 3 1 1 1 318 35.3 5.5 1 1 303942.9375 1 metabolic process cytoplasm;membrane catalytic activity;metal ion binding;protein binding Pf04952 71670 ENSMUSG00000024866.9 Acy3 19 Aflatoxin activation and detoxification 0 High D3Z4M5 Fas-activated serine/threonine kinase OS=Mus musculus OX=10090 GN=Fastk PE=1 SV=1 0.009 1.8 1 1 1 1 516 57.9 9.73 1 1 509747.7188 1 metabolic process catalytic activity "Pf06743, Pf08368, Pf08373" ENSMUSG00000028959.14 5 0 Low Q3TVI8 Pre-B-cell leukemia transcription factor-interacting protein 1 OS=Mus musculus OX=10090 GN=Pbxip1 PE=1 SV=2 0.053 1.018 2 1 1 1 727 81.1 5.36 1 1 2713779.25 2961869.25 3646808.25 1 1 1 cell differentiation;regulation of biological process cytoplasm;cytoskeleton;nucleus 229534 ENSMUSG00000042613.9 Pbxip1 3 0 High Q8R3P0 Aspartoacylase OS=Mus musculus OX=10090 GN=Aspa PE=1 SV=2 0.009 1.825 4 1 1 1 312 35.3 6.58 1 1 318563.0938 1 metabolic process;regulation of biological process cytoplasm;cytosol;nucleus catalytic activity;metal ion binding;protein binding Pf04952 11484 ENSMUSG00000020774.9 Aspa 11 Amino acid synthesis and interconversion (transamination) "Histidine metabolism; Metabolic pathways; Alanine, aspartate and glutamate metabolism" 0 High D3Z3F1 FIP1-like 1 protein (Fragment) OS=Mus musculus OX=10090 GN=Fip1l1 PE=1 SV=2 0 4.794 4 1 1 1 434 46.4 4.74 1 1 677255.1875 1607294.625 1 1 Pf05182 ENSMUSG00000029227.15 5 0 Medium Q8K4Z5 Splicing factor 3A subunit 1 OS=Mus musculus OX=10090 GN=Sf3a1 PE=1 SV=1 0.017 1.37 1 1 1 1 791 88.5 5.22 1 1 136320.25 2251416.75 1 1 cell organization and biogenesis;metabolic process;regulation of biological process nucleus;spliceosomal complex protein binding;RNA binding "Pf00240, Pf01805, Pf12230, Pf14560" 67465 ENSMUSG00000002129.11 Sf3a1 11 mRNA Splicing - Major Pathway Spliceosome 0 High E9Q3B1 RCC1 and BTB domain-containing protein 2 OS=Mus musculus OX=10090 GN=Rcbtb2 PE=1 SV=1 0.01 1.718 3 1 1 1 517 56.3 5.47 1 1 603036.8125 1 protein binding "Pf00415, Pf00651, Pf13540" ENSMUSG00000022106.14 14 0 High Q3UEB3 Poly(U)-binding-splicing factor PUF60 OS=Mus musculus OX=10090 GN=Puf60 PE=1 SV=2 0 5.456 3 1 1 1 564 60.2 5.29 1 1 cell death;metabolic process;regulation of biological process nucleus DNA binding;protein binding;RNA binding "Pf00076, Pf13893, Pf14259" 67959 ENSMUSG00000002524.15 Puf60 15 mRNA Splicing - Major Pathway Spliceosome 0 High Q91YV9 Post-GPI attachment to proteins factor 4 OS=Mus musculus OX=10090 GN=Pgap4 PE=2 SV=1 0.004 2.429 2 1 1 1 403 46.6 7.39 1 1 5461320.5 1 membrane 67063 ENSMUSG00000039611.2 Tmem246 4 0 Medium O88967 ATP-dependent zinc metalloprotease YME1L1 OS=Mus musculus OX=10090 GN=Yme1l1 PE=1 SV=1 0.023 1.286 1 1 1 1 715 80 8.97 1 1 cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process;response to stimulus membrane;mitochondrion catalytic activity;metal ion binding;nucleotide binding "Pf00004, Pf01078, Pf01434, Pf05496, Pf06068, Pf07724, Pf07728, Pf13191, Pf13207, Pf13401, Pf13481" 27377 ENSMUSG00000026775.9 Yme1l1 2 Processing of SMDT1 0 Medium P97384 Annexin A11 OS=Mus musculus OX=10090 GN=Anxa11 PE=1 SV=2 0.015 1.493 2 1 1 1 503 54 7.66 1 1 315078.4375 1 cell division;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;membrane;nucleus;vacuole metal ion binding;protein binding;RNA binding Pf00191 11744 ENSMUSG00000021866.15 Anxa11 14 0 High A0A0R4J119 Cytoplasmic FMR1-interacting protein OS=Mus musculus OX=10090 GN=Cyfip1 PE=1 SV=1 0 3.781 1 1 1 1 1251 144.8 6.95 1 1 cell differentiation;cell growth;cell organization and biogenesis;development;regulation of biological process;response to stimulus cytoplasm protein binding;RNA binding "Pf05994, Pf07159" 20430 ENSMUSG00000030447.15 Cyfip1 7 0 Low Q3V362 Zinc finger protein 251 (Fragment) OS=Mus musculus OX=10090 GN=Zfp251 PE=2 SV=1 0.078 0.798 1 1 1 1 622 69.8 8.46 1 1 1164415.125 2785173.5 7874634.5 8028809.5 1 1 1 1 regulation of biological process metal ion binding "Pf00096, Pf01352, Pf13465" 71591 Zfp251 15 0 High P61620 Protein transport protein Sec61 subunit alpha isoform 1 OS=Mus musculus OX=10090 GN=Sec61a1 PE=1 SV=2 0.004 2.544 2 1 1 1 476 52.2 8.06 1 1 3528418.25 1 cell growth;cell organization and biogenesis;development;response to stimulus;transport endoplasmic reticulum;membrane transporter activity "Pf00344, Pf10559" 53421 ENSMUSG00000030082.14 Sec61a1 6 XBP1(S) activates chaperone genes Phagosome; Protein export; Protein processing in endoplasmic reticulum 0 Medium F2Z483 T-complex protein 1 subunit alpha OS=Mus musculus OX=10090 GN=Tcp1 PE=1 SV=1 0.034 1.117 10 1 1 1 103 11 4.67 1 1 3878059.25 4638083 3714668 9550597 1 1 1 1 metabolic process nucleotide binding;protein binding Pf00118 ENSMUSG00000068039.12 17 0 High E9PXX7 Thioredoxin domain-containing protein 5 OS=Mus musculus OX=10090 GN=Txndc5 PE=1 SV=1 0 7.957 6 1 1 1 344 38.5 5.39 1 1 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport endoplasmic reticulum;organelle lumen catalytic activity "Pf00085, Pf07449, Pf13098, Pf13905" 105245 ENSMUSG00000038991.16 Txndc5 13 0 Medium A0A571BEC9 Perilipin-4 OS=Mus musculus OX=10090 GN=Plin4 PE=1 SV=1 0.013 1.544 4 1 1 1 1601 158.6 8.76 1 1 0 Medium H3BK73 Prosalusin (Fragment) OS=Mus musculus OX=10090 GN=Tor2a PE=1 SV=1 0.012 1.619 7 1 1 1 268 30.2 7.9 1 1 cell organization and biogenesis organelle lumen nucleotide binding Pf06309 ENSMUSG00000009563.16 2 0 Medium Q80VD1 Protein FAM98B OS=Mus musculus OX=10090 GN=Fam98b PE=1 SV=1 0.011 1.634 3 1 1 1 429 45.3 8.5 1 1 metabolic process;regulation of biological process cytoplasm;nucleus catalytic activity;protein binding;RNA binding Pf10239 68215 ENSMUSG00000027349.5 Fam98b 2 0 Medium P47753 F-actin-capping protein subunit alpha-1 OS=Mus musculus OX=10090 GN=Capza1 PE=1 SV=4 0.016 1.446 5 1 1 1 286 32.9 5.55 1 1 cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton;membrane protein binding Pf01267 12340 Capza1 3 Endocytosis 0 High Q91WR3 Activating signal cointegrator 1 complex subunit 2 OS=Mus musculus OX=10090 GN=Ascc2 PE=1 SV=1 0 4.132 3 1 1 1 749 85.6 5.03 1 1 36854.75 214637.5781 427861.4375 1 1 1 metabolic process;regulation of biological process nucleus protein binding Pf02845 75452 ENSMUSG00000020412.16 Ascc2 11 0 High Q61191 Host cell factor 1 OS=Mus musculus OX=10090 GN=Hcfc1 PE=1 SV=2 0 4.901 1 1 1 1 2045 210.3 7.18 1 1 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus catalytic activity;protein binding "Pf01344, Pf13415, Pf13418, Pf13854, Pf13964" 15161 ENSMUSG00000031386.14 Hcfc1 X HATs acetylate histones; UCH proteinases Herpes simplex infection 0 High D6RGA5 Pre-mRNA-splicing factor SPF27 OS=Mus musculus OX=10090 GN=Bcas2 PE=1 SV=1 0.007 1.936 37 1 1 1 78 8.6 4.65 1 1 130005.2031 127596.2813 221144.0313 180107.5156 1 1 1 1 Met-loss+Acetyl [N-Term] metabolic process Pf05700 ENSMUSG00000005687.14 3 0 Low P28271 Cytoplasmic aconitate hydratase OS=Mus musculus OX=10090 GN=Aco1 PE=1 SV=3 0.053 0.994 2 1 1 1 889 98.1 7.5 1 1 605311.3125 1 cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytosol;endoplasmic reticulum;Golgi;mitochondrion catalytic activity;metal ion binding;RNA binding "Pf00330, Pf00694" 11428 ENSMUSG00000028405.9 Aco1 4 Iron uptake and transport Citrate cycle (TCA cycle); Metabolic pathways; Biosynthesis of amino acids; 2-Oxocarboxylic acid metabolism; Carbon metabolism; Glyoxylate and dicarboxylate metabolism 0 High E9Q265 Formylglycine-generating enzyme OS=Mus musculus OX=10090 GN=Sumf1 PE=1 SV=1 0.001 3.537 5 1 1 1 347 37.8 7.42 1 1 endoplasmic reticulum protein binding Pf03781 ENSMUSG00000030101.15 6 0 High Q61585 G0/G1 switch protein 2 OS=Mus musculus OX=10090 GN=G0s2 PE=1 SV=1 0.003 2.748 12 1 1 1 103 11.1 8.32 1 1 cell death;regulation of biological process;response to stimulus membrane;mitochondrion Pf15103 14373 ENSMUSG00000009633.3 G0s2 1 0 High P13020 Gelsolin OS=Mus musculus OX=10090 GN=Gsn PE=1 SV=3 0.007 2.009 1 1 1 1 780 85.9 6.18 1 1 623426.625 1 cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;extracellular;membrane;nucleus metal ion binding;protein binding Pf00626 227753 ENSMUSG00000026879.14 Gsn 2 Neutrophil degranulation; Caspase-mediated cleavage of cytoskeletal proteins Regulation of actin cytoskeleton; Fc gamma R-mediated phagocytosis; Viral carcinogenesis 0 Medium P62715 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform OS=Mus musculus OX=10090 GN=Ppp2cb PE=1 SV=1 0.017 1.375 3 1 1 1 309 35.6 5.43 1 1 257949.625 1376168.625 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus chromosome;cytoplasm;cytoskeleton;cytosol;nucleus catalytic activity;metal ion binding;protein binding Pf00149 19053 ENSMUSG00000009630.10 Ppp2cb 8 "RAF activation; Interleukin-20 family signaling; Cyclin A/B1/B2 associated events during G2/M transition; Resolution of Sister Chromatid Cohesion; Separation of Sister Chromatids; Spry regulation of FGF signaling; Beta-catenin phosphorylation cascade; Activated TLR4 signalling; Signaling by GPCR; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Regulation of TP53 Degradation; CTLA4 inhibitory signaling; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Negative regulation of MAPK pathway; Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal; RHO GTPases Activate Formins; ERKs are inactivated; DARPP-32 events" mRNA surveillance pathway; Chagas disease (American trypanosomiasis); Dopaminergic synapse; Hippo signaling pathway; Oocyte meiosis; Sphingolipid signaling pathway; Long-term depression; TGF-beta signaling pathway; Hepatitis C; PI3K-Akt signaling pathway; AMPK signaling pathway; Tight junction; Adrenergic signaling in cardiomyocytes 0 High A2AVA0 "Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 OS=Mus musculus OX=10090 GN=Svep1 PE=1 SV=1" 0.004 2.491 0 1 1 1 3567 387.2 5.57 1 1 cytoplasm;extracellular;membrane metal ion binding;protein binding "Pf00008, Pf00084, Pf00092, Pf00354, Pf02210, Pf02494, Pf07645, Pf07699, Pf12947, Pf13385, Pf13519" 64817 ENSMUSG00000028369.15 Svep1 4 0 High Q8BXA5 Cleft lip and palate transmembrane protein 1-like protein OS=Mus musculus OX=10090 GN=Clptm1l PE=1 SV=1 0 4.425 2 1 1 1 539 62.1 8.84 1 1 cell death membrane Pf05602 218335 ENSMUSG00000021610.7 Clptm1l 13 0 High A0A3B2W3I1 "Vomeronasal 2, receptor 3 OS=Mus musculus OX=10090 GN=Vmn2r3 PE=4 SV=1" 0.001 3.367 5 1 1 1 470 54 7.91 1 1 0 Medium Q9DB91 Mediator of RNA polymerase II transcription subunit 29 OS=Mus musculus OX=10090 GN=Med29 PE=2 SV=1 0.016 1.47 4 1 1 1 199 21 6.29 1 1 849142.3125 1 metabolic process;regulation of biological process nucleus Pf11568 67224 ENSMUSG00000003444.8 Med29 7 Mus musculus biological processes; Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes 0 High Q99KB8 "Hydroxyacylglutathione hydrolase, mitochondrial OS=Mus musculus OX=10090 GN=Hagh PE=1 SV=2" 0.001 3.617 5 1 1 1 309 34.1 7.75 1 1 660060.25 1 metabolic process cytoplasm;mitochondrion;organelle lumen catalytic activity;metal ion binding Pf00753 14651 Hagh 17 Pyruvate metabolism 0 Medium Q07076 Annexin A7 OS=Mus musculus OX=10090 GN=Anxa7 PE=1 SV=2 0.015 1.502 2 1 1 1 463 49.9 6.18 1 1 1243558.625 1 cell differentiation;cell organization and biogenesis;cell proliferation;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus cytosol;membrane;nucleus metal ion binding;protein binding;RNA binding Pf00191 11750 ENSMUSG00000021814.16 Anxa7 14 0 Medium B2LVG5 Cleavage and polyadenylation specificity factor subunit 4 OS=Mus musculus OX=10090 GN=Cpsf4 PE=1 SV=1 0.027 1.171 3 1 1 1 243 27.4 8.22 1 1 743903.5 1 metabolic process nucleus catalytic activity;metal ion binding;RNA binding 54188 ENSMUSG00000029625.16 Cpsf4 5 0 High P52850 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 OS=Mus musculus OX=10090 GN=Ndst2 PE=1 SV=1 0.006 2.073 1 1 1 1 883 101.1 8.7 1 1 2897694.75 1 metabolic process;regulation of biological process Golgi;membrane catalytic activity "Pf00685, Pf12062" 17423 ENSMUSG00000039308.5 Ndst2 14 HS-GAG biosynthesis Metabolic pathways; Glycosaminoglycan biosynthesis - heparan sulfate / heparin 0 Low Q03311 Cholinesterase OS=Mus musculus OX=10090 GN=Bche PE=1 SV=2 0.078 0.813 1 1 1 1 603 68.4 7.25 1 1 2513301 3945952.5 4297055 8635542 1 1 1 1 cell differentiation;metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;extracellular;membrane;organelle lumen catalytic activity;protein binding "Pf00135, Pf07859, Pf08674, Pf14476" 12038 ENSMUSG00000027792.11 Bche 3 "Synthesis, secretion, and deacylation of Ghrelin" 0 High Q8K2Y7 "39S ribosomal protein L47, mitochondrial OS=Mus musculus OX=10090 GN=Mrpl47 PE=1 SV=2" 0.004 2.342 6 1 1 1 252 29.7 10.21 1 1 cell organization and biogenesis;metabolic process mitochondrion;ribosome structural molecule activity Pf06984 74600 ENSMUSG00000037531.8 Mrpl47 3 Mitochondrial translation termination; Mitochondrial translation elongation 0 High Q8BYB9 Protein O-glucosyltransferase 1 OS=Mus musculus OX=10090 GN=Poglut1 PE=1 SV=2 0.004 2.568 2 1 1 1 392 46.4 8.85 1 1 development;metabolic process;regulation of biological process endoplasmic reticulum;organelle lumen catalytic activity;protein binding Pf05686 224143 ENSMUSG00000034064.14 Poglut1 16 Other types of O-glycan biosynthesis 0 High B1ATE0 N-sulfoglucosamine sulfohydrolase (sulfamidase) OS=Mus musculus OX=10090 GN=Sgsh PE=1 SV=1 0.001 3.547 3 1 1 1 422 46.3 7.66 1 1 5779196.5 1 metabolic process vacuole catalytic activity;protein binding "Pf00884, Pf01663" 27029 ENSMUSG00000005043.13 Sgsh 11 HS-GAG degradation 0 High A2AC13 Ras-related C3 botulinum toxin substrate 3 (Fragment) OS=Mus musculus OX=10090 GN=Rac3 PE=1 SV=1 0.003 3.199 5 1 1 1 185 20.7 8.22 1 1 cell communication;cell organization and biogenesis;regulation of biological process;response to stimulus cytoplasm;cytoskeleton;cytosol;membrane catalytic activity;nucleotide binding;protein binding "Pf00071, Pf08477" 170758 ENSMUSG00000018012.11 Rac3 11 0 High D3YTP8 U6 snRNA-associated Sm-like protein LSm4 (Fragment) OS=Mus musculus OX=10090 GN=Lsm4 PE=1 SV=8 0.006 2.303 8 1 1 1 96 11.1 8.88 1 1 75107.80469 364468.6875 188595.75 1 1 1 Acetyl [N-Term] metabolic process Pf01423 ENSMUSG00000031848.15; ENSMUSG00000110900.1 8; CHR_MG190_MG3751_PATCH mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease 0 High Q5SUT0 RNA-binding protein EWS OS=Mus musculus OX=10090 GN=Ewsr1 PE=1 SV=1 0.006 2.06 4 1 1 1 618 64.9 9.38 1 1 6834861 5286116.5 2683992.75 1 1 1 metabolic process;regulation of biological process cytoplasm;membrane;nucleus metal ion binding;protein binding;RNA binding "Pf00076, Pf00641, Pf14259" 14030 ENSMUSG00000009079.16 Ewsr1 11 0 High Q8BXL7 ADP-ribosylation factor-related protein 1 OS=Mus musculus OX=10090 GN=Arfrp1 PE=1 SV=2 0.006 2.224 5 1 1 1 201 22.6 6.55 1 1 Acetyl [N-Term] cell organization and biogenesis;regulation of biological process;response to stimulus;transport cytosol;Golgi;membrane catalytic activity;nucleotide binding;protein binding;signal transducer activity "Pf00025, Pf00071, Pf00503, Pf01926, Pf04670, Pf08477, Pf09439" 76688 ENSMUSG00000038671.15 Arfrp1 2 Retrograde transport at the Trans-Golgi-Network 0 High Q8C863 E3 ubiquitin-protein ligase Itchy OS=Mus musculus OX=10090 GN=Itch PE=1 SV=2 0.004 2.528 1 1 1 1 864 98.9 6.28 1 1 1443162.75 1309859.625 1 1 cell death;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;cytosol;endosome;membrane;nucleus catalytic activity;protein binding "Pf00168, Pf00397, Pf00632" 16396 ENSMUSG00000027598.16 Itch 2 Activated NOTCH1 Transmits Signal to the Nucleus; Hedgehog 'on' state; Downregulation of ERBB4 signaling; Degradation of GLI1 by the proteasome; NOD1/2 Signaling Pathway; RUNX1 regulates transcription of genes involved in differentiation of HSCs Endocytosis; Ubiquitin mediated proteolysis; TNF signaling pathway; Non-alcoholic fatty liver disease (NAFLD) 0 Medium E0CXZ0 Nucleolar protein 56 OS=Mus musculus OX=10090 GN=Nop56 PE=1 SV=1 0.012 1.554 8 1 1 1 261 29.1 7.18 1 1 299878.0313 690449.625 625483.6875 1 1 1 "Pf08060, Pf08156" ENSMUSG00000027405.16 2 0 High A0A338P6U4 "Presenilins-associated rhomboid-like protein, mitochondrial OS=Mus musculus OX=10090 GN=Parl PE=1 SV=1" 0.006 2.072 3 1 1 1 343 38.4 9.95 1 1 0 High A0A494B987 DNA damage-binding protein 1 OS=Mus musculus OX=10090 GN=Ddb1 PE=1 SV=1 0.007 1.988 2 1 1 1 451 50.5 5.24 1 1 333939.0938 1 0 Low Q9JIK5 Nucleolar RNA helicase 2 OS=Mus musculus OX=10090 GN=Ddx21 PE=1 SV=3 0.08 0.75 2 1 1 1 851 93.5 9.11 1 1 cell differentiation;metabolic process;response to stimulus cytoplasm;membrane;nucleus catalytic activity;nucleotide binding;protein binding;RNA binding "Pf00270, Pf00271, Pf08152, Pf14617" 56200 ENSMUSG00000020075.8 Ddx21 10 Major pathway of rRNA processing in the nucleolus and cytosol; B-WICH complex positively regulates rRNA expression 0 Medium Q78J03 "Methionine-R-sulfoxide reductase B2, mitochondrial OS=Mus musculus OX=10090 GN=Msrb2 PE=1 SV=1" 0.025 1.236 5 1 1 1 175 19.1 9.06 1 1 535026.8125 1 cell organization and biogenesis;metabolic process;response to stimulus mitochondrion catalytic activity;metal ion binding;protein binding Pf01641 76467 ENSMUSG00000023094.14 Msrb2 2 Protein repair 0 High Q921K8 TRPM8 channel-associated factor 2 OS=Mus musculus OX=10090 GN=Tcaf2 PE=1 SV=1 0.003 2.818 2 1 1 1 919 101.5 6.52 1 1 377647.375 1 cell differentiation;regulation of biological process;transport membrane protein binding Pf13402 232748 ENSMUSG00000029851.5 Fam115c; Tcaf2 6 0 High Q8BFW7 Lipoma-preferred partner homolog OS=Mus musculus OX=10090 GN=Lpp PE=1 SV=1 0.007 1.925 2 1 1 1 613 65.8 7.37 1 1 480161.1875 1 cytoplasm;cytosol;nucleus metal ion binding;protein binding "Pf00412, Pf02318" 210126 ENSMUSG00000033306.14 Lpp 16 0 High A0A075B5V5 Immunoglobulin heavy variable 1-39 (Fragment) OS=Mus musculus OX=10090 GN=Ighv1-39 PE=4 SV=1 0.003 3.237 13 1 1 1 117 12.9 8.41 1 1 2720381.5 1 cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus protein binding "Pf00047, Pf07686" ENSMUSG00000095130.1 12 0 High Q3U422 Complex I-9kD OS=Mus musculus OX=10090 GN=Ndufv3 PE=1 SV=1 0 3.723 7 1 1 1 468 50.5 8.97 1 1 885917.8125 1 metabolic process;transport membrane;mitochondrion RNA binding Pf10243 78330 ENSMUSG00000024038.16 Ndufv3 17 0 High A0A1L1ST61 "HIG1 domain family member 1A, mitochondrial (Fragment) OS=Mus musculus OX=10090 GN=Higd1a PE=1 SV=1" 0.003 2.697 25 1 1 1 76 8.2 9.91 1 1 Met-loss+Acetyl [N-Term] membrane Pf04588 ENSMUSG00000038412.8 9 0 High O09111 "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial OS=Mus musculus OX=10090 GN=Ndufb11 PE=1 SV=2" 0.004 2.56 7 1 1 1 151 17.4 5.22 1 1 652230.125 4902277 1 1 cell organization and biogenesis;metabolic process;transport membrane;mitochondrion Pf10183 104130 ENSMUSG00000031059.9 Ndufb11 X Complex I biogenesis Metabolic pathways; Huntington's disease; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinson's disease; Alzheimer's disease 0 High Q9EP52 Twisted gastrulation protein homolog 1 OS=Mus musculus OX=10090 GN=Twsg1 PE=1 SV=1 0 5.984 7 1 1 1 222 24.8 5.5 1 1 cell differentiation;development;regulation of biological process;response to stimulus extracellular protein binding Pf04668 65960 ENSMUSG00000024098.5 Twsg1 17 0 Medium D3Z5Y1 StAR-related lipid transfer protein 13 (Fragment) OS=Mus musculus OX=10090 GN=Stard13 PE=1 SV=1 0.031 1.126 6 1 1 1 111 13.1 8.69 1 1 29604892 38888704 8337609 1 1 1 protein binding Pf07647 ENSMUSG00000016128.14 5 0 High Q9CQ92 Mitochondrial fission 1 protein OS=Mus musculus OX=10090 GN=Fis1 PE=1 SV=1 0 5.271 10 1 1 1 152 17 8.53 1 1 Acetyl [N-Term] cell death;cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport endoplasmic reticulum;membrane;mitochondrion protein binding "Pf14852, Pf14853" 66437 ENSMUSG00000019054.13 Fis1 5 0 High P63037 DnaJ homolog subfamily A member 1 OS=Mus musculus OX=10090 GN=Dnaja1 PE=1 SV=1 0 4.002 3 1 1 1 397 44.8 7.08 1 1 cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;cytosol;endoplasmic reticulum;membrane;mitochondrion;nucleus enzyme regulator activity;metal ion binding;nucleotide binding;protein binding "Pf00226, Pf00684, Pf01556" 15502 ENSMUSG00000028410.13 Dnaja1 4 HSP90 chaperone cycle for steroid hormone receptors (SHR) Protein processing in endoplasmic reticulum 0 High Q8CIE6 Coatomer subunit alpha OS=Mus musculus OX=10090 GN=Copa PE=1 SV=2 0.004 2.352 1 1 1 1 1224 138.3 7.65 1 1 5152062.5 1 regulation of biological process;transport cytoplasm;extracellular;Golgi;membrane protein binding;structural molecule activity "Pf00400, Pf04053, Pf06957" 12847 ENSMUSG00000026553.17 Copa 1 COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic 0 Medium Q9CR63 "Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial OS=Mus musculus OX=10090 GN=Cox16 PE=3 SV=1" 0.01 1.665 8 1 1 1 106 12.3 9.82 1 1 membrane;mitochondrion Pf14138 66272 ENSMUSG00000091803.7 Cox16 12 0 High A0A0U1RP53 Dedicator of cytokinesis protein 7 (Fragment) OS=Mus musculus OX=10090 GN=Dock7 PE=1 SV=1 0.006 2.237 10 1 1 1 102 11.8 6.67 1 1 494759.5938 1 regulation of biological process;response to stimulus ENSMUSG00000028556.15 4 MET activates RAP1 and RAC1 0 Medium E9PU93 Set1/Ash2 histone methyltransferase complex subunit ASH2 OS=Mus musculus OX=10090 GN=Ash2l PE=1 SV=1 0.013 1.553 2 1 1 1 534 60.1 6.95 1 1 1896191.5 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus nucleus catalytic activity;DNA binding;metal ion binding;protein binding Pf00622 23808 ENSMUSG00000031575.18 Ash2l 8 0 High A0A0R4J139 Peptide-methionine (R)-S-oxide reductase OS=Mus musculus OX=10090 GN=Msrb3 PE=1 SV=1 0.003 2.692 5 1 1 1 186 20.2 6.71 1 1 3991045.5 1 metabolic process;response to stimulus endoplasmic reticulum;mitochondrion catalytic activity;metal ion binding Pf01641 320183 ENSMUSG00000051236.13 Msrb3 10 Protein repair 0 High P30275 "Creatine kinase U-type, mitochondrial OS=Mus musculus OX=10090 GN=Ckmt1 PE=1 SV=1" 0.003 2.734 2 1 1 1 418 47 8.16 1 1 1465357 1 metabolic process;regulation of biological process membrane;mitochondrion catalytic activity;nucleotide binding;protein binding "Pf00217, Pf02807" 12716 ENSMUSG00000000308.14 Ckmt1 2 Creatine metabolism Arginine and proline metabolism; Metabolic pathways 0 High O35657 Sialidase-1 OS=Mus musculus OX=10090 GN=Neu1 PE=1 SV=1 0 5.243 9 1 1 1 409 44.6 6.02 1 1 metabolic process;regulation of biological process cell surface;membrane;organelle lumen;vacuole catalytic activity;protein binding "Pf13088, Pf13859" 18010 ENSMUSG00000007038.5 Neu1 17 Neutrophil degranulation; Sialic acid metabolism; Glycosphingolipid metabolism Lysosome; Sphingolipid metabolism; Other glycan degradation 0 High Q9JKX3 Transferrin receptor protein 2 OS=Mus musculus OX=10090 GN=Tfr2 PE=1 SV=2 0.006 2.094 2 1 1 1 798 88.3 6.13 1 1 196513.4219 1 cellular homeostasis;defense response;regulation of biological process;response to stimulus;transport cytoplasm;membrane protein binding;receptor activity "Pf02225, Pf04253, Pf04389" 50765 ENSMUSG00000029716.13 Tfr2 5 Transferrin endocytosis and recycling 0 High P63005 Platelet-activating factor acetylhydrolase IB subunit beta OS=Mus musculus OX=10090 GN=Pafah1b1 PE=1 SV=2 0.007 1.85 2 1 1 1 410 46.6 7.37 1 1 5104955.5 1 cell communication;cell differentiation;cell division;cell organization and biogenesis;cell proliferation;cellular component movement;development;metabolic process;regulation of biological process;response to stimulus;transport chromosome;cytoplasm;cytoskeleton;cytosol;membrane;nucleus protein binding "Pf00400, Pf08513, Pf11715" 18472 ENSMUSG00000020745.15 Pafah1b1 11 Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes; Resolution of Sister Chromatid Cohesion; Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal; Separation of Sister Chromatids; COPI-independent Golgi-to-ER retrograde traffic; RHO GTPases Activate Formins Metabolic pathways; Ether lipid metabolism 0 High Q62241 U1 small nuclear ribonucleoprotein C OS=Mus musculus OX=10090 GN=Snrpc PE=1 SV=1 0 4.503 11 1 1 1 159 17.4 9.67 1 1 842145.0625 2346688 8939937 3148364 1 1 1 1 cell organization and biogenesis;metabolic process nucleus;spliceosomal complex metal ion binding;protein binding;RNA binding Pf06220 20630 ENSMUSG00000024217.9 Snrpc 17 mRNA Splicing - Major Pathway Spliceosome 0 High Q64133 Amine oxidase [flavin-containing] A OS=Mus musculus OX=10090 GN=Maoa PE=1 SV=3 0.006 2.063 2 1 1 1 526 59.6 7.81 1 1 96306.34375 6499512.5 1 1 metabolic process;transport membrane;mitochondrion catalytic activity;nucleotide binding;protein binding "Pf00070, Pf00890, Pf01266, Pf01494, Pf01593, Pf01946, Pf02254, Pf03486, Pf07992, Pf12831, Pf13450" 17161 ENSMUSG00000025037.6 Maoa X Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB; Metabolism of serotonin; Norepinephrine Neurotransmitter Release Cycle; Enzymatic degradation of Dopamine by monoamine oxidase; Enzymatic degradation of dopamine by COMT "Histidine metabolism; Arginine and proline metabolism; Tryptophan metabolism; Dopaminergic synapse; Drug metabolism - cytochrome P450; Metabolic pathways; Amphetamine addiction; Glycine, serine and threonine metabolism; Cocaine addiction; Alcoholism; Phenylalanine metabolism; Tyrosine metabolism; Serotonergic synapse" 0 High Q7TT50 Serine/threonine-protein kinase MRCK beta OS=Mus musculus OX=10090 GN=Cdc42bpb PE=1 SV=2 0.004 2.462 1 1 1 1 1713 194.6 6.46 1 1 352784.9063 3489291.75 1 1 cell differentiation;cell organization and biogenesis;cellular component movement;metabolic process;regulation of biological process;response to stimulus;transport cytoplasm;cytoskeleton;Golgi;membrane catalytic activity;metal ion binding;motor activity;nucleotide binding;protein binding "Pf00069, Pf00130, Pf00261, Pf00433, Pf00769, Pf00780, Pf00786, Pf01576, Pf02463, Pf03148, Pf03962, Pf04111, Pf04156, Pf04849, Pf05276, Pf05483, Pf05557, Pf05622, Pf05667, Pf05701, Pf06008, Pf06160, Pf07111, Pf07321, Pf07714, Pf07888, Pf07926, Pf08317, Pf08826, Pf09726, Pf09728, Pf09730, Pf09731, Pf09787, Pf10174, Pf10473, Pf10498, Pf12072, Pf12128, Pf12718, Pf12795, Pf13514, Pf13851, Pf13868, Pf13870, Pf14817, Pf14988, Pf14992, Pf15035, Pf15294, Pf15558, Pf15619" 217866 ENSMUSG00000021279.4 Cdc42bpb 12 0 High Q9DBG7 Signal recognition particle receptor subunit alpha OS=Mus musculus OX=10090 GN=Srpra PE=1 SV=1 0 4.394 2 1 1 1 636 69.6 8.95 1 1 cell organization and biogenesis;transport endoplasmic reticulum;membrane catalytic activity;nucleotide binding;RNA binding "Pf00448, Pf02881, Pf04086" 67398 ENSMUSG00000032042.11 Srpr 9 Protein export 0 Medium A0A1L1STE4 Interleukin enhancer-binding factor 3 OS=Mus musculus OX=10090 GN=Ilf3 PE=1 SV=1 0.017 1.36 1 1 1 1 908 97.4 8.92 1 1 278988.625 1 defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;extracellular;membrane;mitochondrion;nucleus DNA binding;protein binding;RNA binding "Pf00035, Pf07528, Pf14709" 16201 ENSMUSG00000032178.14 Ilf3 9 0 High Q8BUV3 Gephyrin OS=Mus musculus OX=10090 GN=Gphn PE=1 SV=2 0 4.084 2 1 1 1 769 83.2 5.6 1 1 639970.375 1 Met-loss+Acetyl [N-Term] cell organization and biogenesis;metabolic process;response to stimulus cytoplasm;cytoskeleton;membrane catalytic activity;metal ion binding;nucleotide binding;protein binding;structural molecule activity "Pf00994, Pf03453, Pf03454" 268566 ENSMUSG00000047454.12 Gphn 12 Molybdenum cofactor biosynthesis GABAergic synapse; Metabolic pathways; Folate biosynthesis 0 Medium A0A1Y7VN70 "Glutaredoxin-related protein 5, mitochondrial OS=Mus musculus OX=10090 GN=Glrx5 PE=1 SV=1" 0.026 1.195 7 1 1 1 118 12.2 7.18 1 1 473052.5625 1 cellular homeostasis;metabolic process;regulation of biological process catalytic activity Pf00462 0 High Q8C7D2 Protein cereblon OS=Mus musculus OX=10090 GN=Crbn PE=1 SV=1 0 5.746 9 1 1 1 445 50.8 5.33 1 1 652508 1 metabolic process;regulation of biological process cytoplasm;membrane;nucleus catalytic activity;metal ion binding Pf02190 58799 ENSMUSG00000005362.14 Crbn 6 0 Medium Q80UG5 Septin-9 OS=Mus musculus OX=10090 GN=Septin9 PE=1 SV=1 0.026 1.174 3 1 1 1 583 65.5 8.9 1 1 cell division;cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton catalytic activity;nucleotide binding;protein binding "Pf00735, Pf01926, Pf03193, Pf04548" 53860 ENSMUSG00000059248.13 Sept9 11 Bacterial invasion of epithelial cells 0 Medium Q569Z5 Probable ATP-dependent RNA helicase DDX46 OS=Mus musculus OX=10090 GN=Ddx46 PE=1 SV=2 0.043 1.038 1 1 1 1 1032 117.4 9.26 1 1 metabolic process;regulation of biological process cytoplasm;membrane;nucleus catalytic activity;nucleotide binding;RNA binding "Pf00270, Pf00271" 212880 ENSMUSG00000021500.15 Ddx46 13 mRNA Splicing - Major Pathway Spliceosome 0 Medium Q3TZ89 Protein transport protein Sec31B OS=Mus musculus OX=10090 GN=Sec31b PE=1 SV=2 0.039 1.062 1 1 1 1 1158 125.6 7.77 1 1 679316.0625 1 transport cytoplasm;endoplasmic reticulum;membrane protein binding Pf00400 240667 ENSMUSG00000051984.13 Sec31b 19 Protein processing in endoplasmic reticulum 0 High F6QSC4 Macrophage galactose N-acetyl-galactosamine-specific lectin 2 (Fragment) OS=Mus musculus OX=10090 GN=Mgl2 PE=1 SV=1 0.01 1.764 2 1 1 1 374 42.6 5.67 1 1 membrane catalytic activity;motor activity "Pf00059, Pf01576, Pf03954" ENSMUSG00000040950.13 11 0 Medium P59999 Actin-related protein 2/3 complex subunit 4 OS=Mus musculus OX=10090 GN=Arpc4 PE=1 SV=3 0.034 1.097 5 1 1 1 168 19.7 8.43 1 1 440936.6875 1 cell organization and biogenesis;regulation of biological process cytoplasm;cytoskeleton protein binding;structural molecule activity Pf05856 68089 ENSMUSG00000079426.13 Arpc4 6 RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling; Regulation of actin dynamics for phagocytic cup formation Endocytosis; Regulation of actin cytoskeleton; Salmonella infection; Fc gamma R-mediated phagocytosis; Bacterial invasion of epithelial cells 0 Medium A0A087WS31 Aspartyl aminopeptidase (Fragment) OS=Mus musculus OX=10090 GN=Dnpep PE=1 SV=1 0.012 1.554 5 1 1 1 222 24.8 9.39 1 1 543228.3125 1638102 1 1 metabolic process catalytic activity;metal ion binding Pf02127 ENSMUSG00000026209.15 1 0 Low E9Q3Z5 Supervillin OS=Mus musculus OX=10090 GN=Svil PE=1 SV=1 0.056 0.971 0 1 1 1 2056 230.3 6.62 1 1 cell organization and biogenesis protein binding "Pf00626, Pf02209" ENSMUSG00000024236.18 18 0 Medium P04370 Myelin basic protein OS=Mus musculus OX=10090 GN=Mbp PE=1 SV=2 0.011 1.652 5 1 1 1 250 27.2 9.58 1 1 1491522.5 4952568 2314189.75 1 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus cytoplasm;membrane;nucleus protein binding;structural molecule activity Pf01669 17196 ENSMUSG00000041607.16 Mbp 18 0 High Q9D1N9 "39S ribosomal protein L21, mitochondrial OS=Mus musculus OX=10090 GN=Mrpl21 PE=1 SV=1" 0.006 2.283 4 1 1 1 209 23.4 9.99 1 1 284648 1 metabolic process mitochondrion;ribosome RNA binding;structural molecule activity Pf00829 353242 ENSMUSG00000024829.12 Mrpl21 19 Mitochondrial translation termination; Mitochondrial translation elongation Ribosome 0 Low Q8C1C2 "Ribosome-releasing factor 2, mitochondrial OS=Mus musculus OX=10090 GN=Gfm2 PE=1 SV=1" 0.055 0.981 1 1 1 1 543 60.5 7.33 1 1 4691811.5 1 cell organization and biogenesis;metabolic process mitochondrion catalytic activity;nucleotide binding "Pf00009, Pf01926, Pf03144, Pf14492" 320806 ENSMUSG00000021666.16 Gfm2 13 0 High P56564 Excitatory amino acid transporter 1 OS=Mus musculus OX=10090 GN=Slc1a3 PE=1 SV=2 0.007 1.887 4 1 1 1 543 59.6 8.4 1 1 cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport cell surface;membrane metal ion binding;protein binding;transporter activity Pf00375 20512 ENSMUSG00000005360.14 Slc1a3 15 Transport of inorganic cations/anions and amino acids/oligopeptides; Astrocytic Glutamate-Glutamine Uptake And Metabolism; Glutamate Neurotransmitter Release Cycle Glutamatergic synapse 0 High Z4YJW0 ER membrane protein complex subunit 1 OS=Mus musculus OX=10090 GN=Emc1 PE=1 SV=1 0.001 3.625 1 1 1 1 997 111.5 7.43 1 1 6538208.5 1 "Pf07774, Pf13360" ENSMUSG00000078517.11 4 0 High Q64310 Surfeit locus protein 4 OS=Mus musculus OX=10090 GN=Surf4 PE=1 SV=1 0.007 1.985 4 1 1 1 269 30.4 7.78 1 1 185055.3281 10631790 1 1 cell organization and biogenesis;regulation of biological process endoplasmic reticulum;Golgi;membrane protein binding Pf02077 20932 ENSMUSG00000014867.9 Surf4 2 COPI-dependent Golgi-to-ER retrograde traffic; Neutrophil degranulation 0 High D3Z7V9 Tripartite motif-containing protein 3 (Fragment) OS=Mus musculus OX=10090 GN=Trim3 PE=1 SV=8 0.006 2.206 3 1 1 1 287 31.8 6.37 1 1 586417.0625 1 catalytic activity;metal ion binding;protein binding "Pf00097, Pf00643, Pf11740, Pf12861, Pf13445, Pf13639, Pf13920, Pf13923, Pf14634, Pf15227" ENSMUSG00000036989.16 7 0 Medium A0A1B0GX27 Branched-chain-amino-acid aminotransferase OS=Mus musculus OX=10090 GN=Bcat2 PE=1 SV=1 0.027 1.185 2 1 1 1 388 43.5 8.43 1 1 metabolic process catalytic activity Pf01063 ENSMUSG00000030826.19 7 0 Low Q8CCN1 "NACHT, LRR and PYD domains-containing protein 10 OS=Mus musculus OX=10090 GN=Nlrp10 PE=1 SV=1" 0.074 0.848 2 1 1 1 673 76.3 6.6 1 1 3237495.25 2404057.5 1 1 defense response;regulation of biological process;response to stimulus cytoplasm;membrane catalytic activity;nucleotide binding "Pf02758, Pf05729, Pf13191" 244202 ENSMUSG00000049709.4 Nlrp10 7 0 Medium A0A1Y7VNF4 ERO1-like protein beta OS=Mus musculus OX=10090 GN=Ero1b PE=1 SV=1 0.017 1.372 1 1 1 1 493 55.9 7.8 1 1 4004555.75 1 cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;transport endoplasmic reticulum;membrane catalytic activity Pf04137 67475 Ero1lb 13 0 High P01741 Ig heavy chain V region OS=Mus musculus OX=10090 PE=1 SV=1 0.001 3.628 11 1 1 1 114 12.5 5.06 1 1 1779303.5 4438427 1 1 Pf07686 0 Medium E9Q2H1 E3 ubiquitin-protein ligase UBR5 OS=Mus musculus OX=10090 GN=Ubr5 PE=1 SV=2 0.016 1.401 1 1 1 1 2792 308.1 5.83 1 1 Met-loss+Acetyl [N-Term] 0 Medium F6QZ47 Catenin beta-1 (Fragment) OS=Mus musculus OX=10090 GN=Ctnnb1 PE=1 SV=1 0.034 1.087 5 1 1 1 145 16.6 7.65 1 1 646840.125 4463899 1 1 protein binding ENSMUSG00000006932.17 9 0 High Q8QZY9 Splicing factor 3B subunit 4 OS=Mus musculus OX=10090 GN=Sf3b4 PE=1 SV=1 0 4.562 3 1 1 1 424 44.3 8.56 1 1 metabolic process;regulation of biological process nucleus;spliceosomal complex RNA binding "Pf00076, Pf13893, Pf14259" 107701 ENSMUSG00000068856.3 Sf3b4 3 mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway Spliceosome 0 Medium E9Q5X5 Galectin-3-binding protein (Fragment) OS=Mus musculus OX=10090 GN=Lgals3bp PE=1 SV=1 0.038 1.073 3 1 1 1 204 21.9 4.65 1 1 433143 2037385.75 1 1 transport membrane receptor activity Pf00530 ENSMUSG00000033880.11 11 0 High Q8BJT9 ER degradation-enhancing alpha-mannosidase-like protein 2 OS=Mus musculus OX=10090 GN=Edem2 PE=1 SV=1 0.001 3.421 2 1 1 1 577 64.6 5.55 1 1 1597598.375 4087583.5 1 1 metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;membrane catalytic activity;metal ion binding;protein binding Pf01532 108687 ENSMUSG00000038312.10 Edem2 2 ER Quality Control Compartment (ERQC) Protein processing in endoplasmic reticulum 0 High Q9QZS0 Collagen alpha-3(IV) chain OS=Mus musculus OX=10090 GN=Col4a3 PE=1 SV=2 0.001 3.444 1 1 1 1 1669 161.6 9.48 1 1 1402771.125 1 cell death;cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process;response to stimulus endoplasmic reticulum;extracellular protein binding;structural molecule activity Pf01413 12828 ENSMUSG00000079465.8 Col4a3 1 Anchoring fibril formation; Laminin interactions; Crosslinking of collagen fibrils; Collagen chain trimerization; Integrin cell surface interactions; NCAM1 interactions; Collagen degradation; Non-integrin membrane-ECM interactions; Signaling by PDGF AGE-RAGE signaling pathway in diabetic complications; Focal adhesion; Protein digestion and absorption; Small cell lung cancer; Pathways in cancer; ECM-receptor interaction; PI3K-Akt signaling pathway; Amoebiasis 0 High Q9ET22 Dipeptidyl peptidase 2 OS=Mus musculus OX=10090 GN=Dpp7 PE=1 SV=2 0.004 2.405 2 1 1 1 506 56.2 5.39 1 1 678686.25 1 metabolic process cytosol;extracellular;Golgi;vacuole catalytic activity "Pf00561, Pf05577" 83768 ENSMUSG00000026958.13 Dpp7 2 Neutrophil degranulation 0 High A2AGS0 E3 ubiquitin-protein ligase TRIM32 (Fragment) OS=Mus musculus OX=10090 GN=Trim32 PE=1 SV=1 0 6.201 12 1 1 1 136 14.9 7.71 1 1 1325870.125 1 Met-loss+Acetyl [N-Term] cell differentiation;cell organization and biogenesis;cellular homeostasis;defense response;metabolic process;regulation of biological process;response to stimulus cytoplasm;nucleus catalytic activity;metal ion binding;protein binding;RNA binding "Pf13445, Pf13639" 69807 ENSMUSG00000051675.13 Trim32 4 0